CN110618008A - Pathological section exhibition piece drags for piece integer machine - Google Patents
Pathological section exhibition piece drags for piece integer machine Download PDFInfo
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- CN110618008A CN110618008A CN201911015477.6A CN201911015477A CN110618008A CN 110618008 A CN110618008 A CN 110618008A CN 201911015477 A CN201911015477 A CN 201911015477A CN 110618008 A CN110618008 A CN 110618008A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
- G01N2001/2873—Cutting or cleaving
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- Sampling And Sample Adjustment (AREA)
Abstract
The invention provides a pathological section display and slide fishing and slicing machine which comprises a bottom plate, and a slicing mechanism, a display mechanism, a slide fishing mechanism and a slide glass receiving mechanism which are respectively arranged on the bottom plate. The device can realize automatic section, exhibition piece, drag for the whole process that the piece and slide glass were accomodate on an instrument, overcomes the defect that only has the product to single process on the market at present. The automatic continuous section of the large pathological tissue is realized, and the multi-angle, multi-level and multi-dimensional pathological tissue characteristic understanding is facilitated.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a pathological section display and slice fishing and arranging machine.
Background
Pathological sections, namely tissue sections, play a very important role in disease diagnosis in modern medicine, and the diagnosis of diseases through pathological sections requires that the thinner the pathological section is, the more accurate the diagnosis is. Since the pathological microtome is a key device for preparing pathological sections, the manufacturing accuracy of the pathological microtome is required to be higher and higher. The current devices are mostly in the research of pathological section devices, for example, patent 201720699606.8 discloses a pathological section machine, which can ensure that the temperature is not increased. According to the invention, the intelligent full-automatic pathological section machine disclosed by the patent 201811202719.8 realizes automation, visualization and intellectualization of the whole pathological section process of the pathological section machine, so that the thickness of a manufactured pathological section can be adjusted to reach the range of 0.5-100 mu m.
The preparation of the sample for pathological diagnosis comprises the steps of slicing, unfolding, fishing and dyeing, the operation process is complex and tedious, and at present, no integrated automatic mechanical equipment is designed for the slicing, unfolding and fishing parts in the market, so the work of making the tissue sample by the pathology department is heavy.
Automatic microtomes on the current market are limited to the section of fritter pathological tissue more, can't accomplish full automatization section, exhibition piece and drag for the piece as an organic whole to great pathological tissue, and the reason has following several: firstly, the large pathological tissues are difficult to slice uniformly; secondly, the pathological tissues are difficult to be completely spread and flattened after being cut into thin slices (about 5 mu m); third, because of the thin and large area special nature of the slices, it is difficult to achieve transfer after flattening. The above requirements are all difficult to achieve by the existing pathological microtomes. The Leica SM2500 slicer is a slicer for cutting large pathological tissues on the market at present, the maximum sample can reach 25 x 20cm, the adjusting range of the slicing speed and the retraction speed is 0.1 mm/sec-100 mm/sec, the slice thickness is adjustable between 0 mu m and 1000 mu m, the maximum sample introduction distance is 70 mm, the defects that the slicing for large samples cannot be automated, and the manual participation is needed for the slice unfolding and the slice fishing, so that the extra labor cost is greatly increased to delay the completion time, and the sample making efficiency is reduced.
With the acceleration of the aging society in China, the number of people needing pathological diagnosis is increased year by year, and how to realize the efficient completion of slicing, spreading and fishing on one device has important significance.
Disclosure of Invention
Aiming at the defects of the prior art, the invention aims to provide a pathological section display and fishing integrated machine which comprises:
1. the whole process of automatic slicing, film unfolding, film fishing and film integration is realized on one instrument, and the defect that products only aim at a single procedure in the market at present is overcome.
2. The continuous section of the large pathological tissue is realized, and the characteristics of the pathological tissue can be known from multiple angles, multiple levels and multiple dimensions.
In order to realize the purpose of the invention, the technical scheme of the invention is as follows:
a pathological section developing machine drags for a piece collator, including the bottom plate, also include the slicing mechanism, developing mechanism, drags for the piece collator and the collator set up on the bottom plate;
the slicing mechanism comprises a bottom plate, a base arranged on the bottom plate and a pathological tissue placing frame connected with the base in a sliding manner, wherein the side wall of the pathological tissue placing frame is provided with at least one adjusting stud for fixing a wax block of the pathological tissue; the front end of the pathological tissue placing frame is connected with a first motor and used for pushing the pathological tissue placing frame to move back and forth on the slide way; the lifting device comprises a lifting base, a lifting rod is arranged at the bottom of the lifting base and connected with a fifth motor, the fifth motor is used for driving the lifting rod to move up and down, and the fifth motor is connected with a bottom plate; a blade holder is arranged at the front end of the lifting base, and a blade is arranged on the blade holder;
the sheet spreading mechanism comprises an aspirator, an aspirator lifting device, an aspirator moving device and a sheet spreading device;
the aspirator is used for sucking up the sliced pathological tissue slices and is arranged above the blade;
the aspirator lifting device is fixedly connected with the aspirator and is used for driving the aspirator to move up and down;
the aspirator moving device is fixedly connected with the aspirator lifting device and is used for driving the aspirator lifting device to move left and right;
the film unfolding device comprises a second conveyor belt, two second rotating shafts and a fourth motor, wherein the two second rotating shafts are arranged on the lifting base and are respectively positioned at the front end and the rear end of the lifting base, the second conveyor belt is arranged between the two second rotating shafts, the fourth motor is connected with any one of the second rotating shafts, and a film unfolding box is arranged on the second conveyor belt;
the piece fishing machine comprises piece fishing device supporting rods, a third rotating shaft is arranged between the two parallel piece fishing device supporting rods, a third conveying belt is arranged between the two third rotating shafts, and a second manipulator is arranged on any one piece fishing device supporting rod; the second manipulator is used for fishing out the glass slide in the slide display box on the second slide display box station and placing the glass slide on the third conveying belt;
the third conveyor belt is connected with the sheet-integrating machine;
the sheet arranging machine comprises a sheet arranging box, a sheet pushing device supporting rod, a thirteenth motor and a fourteenth motor, wherein the sheet arranging box is arranged on one side of a third conveying belt, and the sheet pushing device supporting rod is arranged on the other side of the third conveying belt and is opposite to the sheet arranging box; the sheet pushing device is characterized in that a thirteenth motor is arranged on the supporting rod of the sheet pushing device and connected with the sheet pushing device, a through hole is formed in the bottom plate below the whole sheet box, and a fourteenth motor is arranged at the hole and used for pushing the whole sheet box upwards.
In a further preferred scheme, the slide display device further comprises a slide display platform, a glass slide platform for placing a glass slide and a first manipulator, wherein the slide display platform is fixed on the side wall of the lifting base and is flush with a second conveying belt on the lifting base; the film unfolding platform and the second conveyor belt are provided with a first film unfolding box station, a second film unfolding box station, a third film unfolding box station and a fourth film unfolding box station, a seventh motor is arranged at the second film unfolding box station and used for pushing a film unfolding box on the second film unfolding box station to the third film unfolding box station, a sixth motor is arranged at the third film unfolding box station and used for pushing a film unfolding box on the third film unfolding box station to the fourth film unfolding box station, and a fifth motor is arranged at the fourth film unfolding box station and used for pushing a film unfolding box on the fourth film unfolding box station to the first film unfolding box station; the first manipulator is fixed beside the slide glass platform and is used for sucking and carrying a slide glass into a slide box on a first slide box station;
according to the preferable scheme, the four side walls of the pathological tissue placing frame are respectively provided with at least one adjusting stud, so that the pathological tissue wax block can be better fixed.
According to the preferred scheme, the aspirator is hollow, the bottom of the aspirator is provided with an air hole, one end of the aspirator is provided with a vacuum pump connecting piece, and the other end of the aspirator is fixedly connected with an aspirator lifting device.
The aspirator lifting device can be any existing equipment which can move an aspirator up and down, and further preferably adopts a scheme that the aspirator lifting device comprises a first conveyor belt, an upper connecting rod, a lower connecting rod, a second motor and two first rotating shafts which are respectively arranged at the upper end and the lower end of the upper connecting rod and the lower connecting rod, wherein the first conveyor belt is connected between the two first rotating shafts, one end of the aspirator is provided with a vacuum pump connecting piece, and the other end of the aspirator is fixedly connected with the first conveyor belt; the second motor is connected with any one of the first rotating shafts and drives the first conveyor belt to rotate.
Aspirator mobile device is as long as can wholly remove the current device that removes about aspirator or aspirator hoisting device is with aspirator, further preferred scheme, aspirator mobile device includes two parallel arrangement's vertical branch, sets up horizontal branch, left right transfer bar, third motor between vertical branch, control the transfer bar and be located the below of horizontal branch, and one end is connected on vertical branch, the other end and upper and lower connecting rod swing joint, the third motor is connected with controlling the transfer bar, and the transfer bar rotates about the drive, and the transfer bar direction is controlled in the extension of drive connecting rod about to the drive and moves.
Further preferred scheme, be equipped with the through-hole on the upper and lower connecting rod, be equipped with the screw thread in the through-hole, the conveying rod surface is equipped with the screw thread about, the other end of controlling the conveying rod passes the through-hole on the upper and lower connecting rod, and both pass through threaded connection.
Further preferred scheme, the bottom and the below horizontal branch swing joint of upper and lower connecting rod, also can top and bottom all swing joint. The specific movable connection scheme is preferably as follows: the upper surface of the transverse supporting rod positioned below is provided with a sliding rail, the top end and the bottom end of the upper connecting rod and the lower connecting rod are respectively provided with a sliding device matched with the sliding rail, and the upper connecting rod and the lower connecting rod are connected between the upper transverse supporting rod and the lower transverse supporting rod through the sliding devices. The mode of movably connecting the upper connecting rod and the lower connecting rod between the upper transverse supporting rod and the lower transverse supporting rod has a more stable structure.
Preferably, the lifting rod is provided with a damping device and is positioned above the fifth motor. The method is used for reducing vibration and improving slicing precision.
The optimized scheme further comprises a second conveyor belt, two second rotating shafts and a fourth motor, wherein the two second rotating shafts are arranged on the lifting base and are respectively located at the front end and the rear end of the lifting base, the second conveyor belt is arranged between the two second rotating shafts, and the fourth motor is connected with any one of the second rotating shafts. The conveying device is used for realizing the conveying work after the exhibition of the slices and the slicing.
Preferably, the lifting device further comprises 4 lifting base fixing rods, wherein the four lifting base fixing rods are located on the periphery of the lifting base and connected with the second rotating shaft. For further strengthening of the fixation.
Preferably, the second conveyor belt is further provided with a film box. For storing the slices aspirated by the aspirator.
According to the preferred scheme, N exhibition boxes are arranged among the first exhibition box station, the second exhibition box station, the third exhibition box station and the fourth exhibition box station, and N is larger than or equal to 0.
Preferably, the first mechanical arm comprises a vertical fixing rod, a vertical sliding rod, a cross arm connected between the vertical fixing rod and the vertical sliding rod, and a longitudinal arm crossed with the cross arm, wherein the sliding rod is arranged in the longitudinal arm, the sliding rod penetrates through the sliding piece, a mechanical arm is connected below the sliding piece, a sucker is arranged at the bottom of the mechanical arm, the mechanical arm is hollow inside and is connected with an external vacuum pump through a hole in the sliding piece.
According to the preferable scheme, a ninth motor is arranged on a vertical sliding rod of the first manipulator and used for controlling the cross arm to move up and down; and an eighth motor is arranged on the trailing arm of the first manipulator and used for controlling the sliding piece in the trailing arm to slide.
In the preferred scheme, a tenth motor is arranged on a vertical sliding rod of the second manipulator and used for controlling the cross arm to move up and down; and an eleventh motor is arranged on the trailing arm of the second manipulator and used for controlling the sliding piece in the trailing arm to slide.
Preferably, the first motor, the second motor, the third motor, the fourth motor, the fifth motor, the sixth motor, the seventh motor, the eighth motor, the ninth motor, the tenth motor, the eleventh motor, the twelfth motor, the thirteenth motor, the fourteenth motor, the fifteenth motor and the sixteenth motor are all stepping motors. The slicing precision and the displacement precision are convenient to control.
According to the prior scheme, the sheet-arranging machine is respectively provided with a first sheet-arranging box station, a second sheet-arranging box station, a third sheet-arranging box station and a fourth sheet-arranging box station, the fourth sheet-arranging box station is positioned on a sheet-arranging box platform, the third sheet-arranging box station is flush with the fourth sheet-arranging box station, and a sixteenth motor is arranged on one side of the third sheet-arranging box station and used for pushing the sheet-arranging box on the third sheet-arranging box station onto the fourth sheet-arranging box station; the second whole-piece box station is positioned below the third whole-piece box station, and a fourteenth motor is arranged below the second whole-piece box station and used for pushing the whole-piece box on the second whole-piece box station upwards to the third whole-piece box station; the first integral box station is located behind the second integral box station, and a fifteenth motor is arranged behind the first integral box station and used for pushing the empty integral box into the second integral box station.
The whole piece box is a box body with a hollow inner part, and a plurality of clamping grooves are formed in two side walls of the inner side of the box body and used for placing glass slides.
The invention is further explained and illustrated below
The invention can realize the integration and full automation of slicing, spreading and fishing, and overcomes the defect that the mechanical product only aims at a single procedure in the market at present. The continuous section of the large pathological tissue specimen can know the internal characteristics of pathological tissues in multiple angles, multiple levels and multiple dimensions, and provides guarantee for accurate pathological diagnosis.
The instrument adopts the design of aspirator after the section, can pass through the complete top of transmitting the exhibition piece box of transmitting the light and thin large pathological section of transfer orbit, and the even tiling of section realizes the process of automatic exhibition piece on the surface of water in the exhibition piece box.
The slice fishing is a very fine and labor cost consuming matter, the slice making work is heavier and heavier along with the annual increase of the number of patients, and the problem of how to realize intelligent and automatic slice fishing is worth solving. The fishing piece is used as a precise and complicated process, and the current market is lack of automatic fishing instrument equipment. The applicant realizes automatic salvaging of slices on the basis of automatic slicing and slice spreading, and fills the defects in the field. The design scheme is that after the pathological section is displayed in the display box, the mechanical arm clamps the bottom slide of the display box, and the automatic process of fishing the slide is realized. The slide box can form a closed cycle, thereby realizing the intelligent recycling of the slide box.
Automatically accommodating glass slides: because the area of each glass slide is bigger, the quality is heavier, and it can be more troublesome that the manual handling gets up, so we design an automatic containing box of taking in pathological section, connect automatic section system by the conveyer belt moreover, promote the slide to get into pathological section containing box, by a last lifting containing box of speed reduction control motor again, after waiting to take in the case and pack full load slide, promote containing box shift position. The whole process does not need any manual operation, and the function of automatically storing pathological sections can be completely realized.
Compared with the prior art, the invention has the advantages that:
this section exhibition piece drags for a whole piece machine:
1) the pathological tissue placing frame and the adjusting bolt are designed in the section part, so that pathological tissue wax blocks with any size can be placed, and the section of a large pathological tissue is realized.
2) The motor is used for accurately controlling the front and back movement of the pathological tissue placing frame and the up and down movement of the lifting device, so that the thickness of the slice is accurately controlled.
3) The slice mode adopts the flat push type design of pathological tissue wax block, the blade and the knife rest are stable, and the accurate and stable manufacture of each slice is facilitated.
4) The arrangement of the air aspirator of the slice unfolding part, the air aspirator lifting device and the air aspirator moving device can realize the controlled suction of the sliced pathological section and the transfer to the subsequent slice unfolding process, thereby realizing the integration of slicing and unfolding.
5) The design of exhibition piece device has realized the automatic exhibition piece after the section, need not manual operation, provides the guarantee for follow-up piece process of dragging for.
6) The pathological section automatic fishing machine part can realize automatic fishing of pathological sections and can be detached for use alone, and the front pathological section conveying device is connected with the pathological section conveying device.
7) The automatic collection of pathological section can be realized to the whole slice machine part, reduces artifical work.
8) The design of the integrated slicing, spreading and fishing machine enables the whole slicing process to be smoother, and the working efficiency cannot be influenced by the different proficiency degrees of different technicians.
Drawings
FIG. 1 is a first axial view of a pathological section spreading and scooping whole machine (partial structure) in the embodiment;
FIG. 2 is a second axial view of the pathological section spreading and scooping whole machine (partial structure) in the embodiment;
FIG. 3 is a third axial view of the pathological section spreading and scooping whole machine (partial structure) in the embodiment;
FIG. 4 is a right side view of the pathological section spreading and scooping whole machine (partial structure) in the embodiment;
fig. 5 is a left side view of the slice spreading and sorting machine (partially constructed) of the pathological section machine of the embodiment.
FIG. 6 is a first axial view of a slice spreading and sorting machine (partially constructed) of the pathological section machine of the exemplary embodiment;
FIG. 7 is a second axial view of a slice spreading and sorting machine (partially constructed) of the pathological section machine of the exemplary embodiment;
FIG. 8 is a third axial view of a slice spreading and sorting machine (partially constructed) of the pathological section machine of the exemplary embodiment;
fig. 9 is an axial view of the first robot;
fig. 10 is a top view of the first robot;
FIG. 11 is a view of the shaft of a drag blade of the development drag blade of the pathological section machine in the embodiment;
FIG. 12 is an axial view of a drag piece arranging machine (partially constructed) of the pathological section developing drag piece machine of the embodiment;
FIG. 13 is a shaft view of a drag piece arranging mechanism of the pathological section machine in an embodiment;
FIG. 14 is a shaft view of a drag piece arranging device of the pathological section machine in an embodiment;
FIG. 15 is a schematic view of a monolith box structure;
FIG. 16 is a shaft view of a drag piece arranging device of the pathological section machine in an embodiment;
FIG. 17 is a shaft view of a drag piece arranging device of the pathological section machine in an embodiment;
FIG. 18 is a shaft view of a drag piece arranging device of the pathological section machine in an embodiment;
FIG. 19 is a shaft view of a drag piece arranging mechanism of the pathological section machine in accordance with an exemplary embodiment;
FIG. 20 is a shaft view of a drag piece arranging mechanism of the pathological section machine in accordance with an exemplary embodiment;
FIG. 21 is a schematic view of a preferred embodiment of the present invention including the combination of an aspirator, aspirator lift, and aspirator movement means;
FIG. 22 is a left side view of FIG. 21;
FIG. 23 is a right side view of FIG. 21;
fig. 24 is a bottom view of fig. 21.
Detailed Description
The invention will be further explained and explained with reference to the drawings and the embodiments
As shown in fig. 1-24, a pathological section, exhibition and salvage machine comprises a bottom plate 1, a slicing mechanism, an exhibition mechanism, a salvage machine and a slicing machine arranged on the bottom plate 1;
the slicing mechanism comprises a bottom plate 1 and a base 2 arranged on the bottom plate 1, slide ways 22 are arranged on the inner sides of two side edges of the base 2, a pathological tissue placing frame 3 is arranged on the base 2, and the bottom of the pathological tissue placing frame 3 is connected with the base 2 in a sliding mode through the slide ways 22; the side wall of the pathological tissue placing frame 3 is provided with at least one adjusting stud 4 for fixing a pathological tissue wax block 5; the front end of the pathological tissue placing frame 3 is connected with a first motor 6 which is used for pushing the pathological tissue placing frame 3 to move back and forth on a slideway 5; the lifting device is characterized by further comprising a lifting base 11, wherein a lifting rod 23 is arranged at the bottom of the lifting base 11, the lifting rod 23 is connected with a fifth motor 25, the fifth motor 25 is used for driving the lifting rod 23 to move up and down, and the fifth motor 25 is connected with the bottom plate 1; the front end of the lifting base 11 is provided with a blade frame 9, and the blade frame 9 is provided with a blade 8.
The sheet spreading mechanism comprises an aspirator 7, an aspirator lifting device, an aspirator moving device and a sheet spreading device;
the aspirator 7 is used for sucking up the sliced pathological tissue slice, and the aspirator 7 is arranged above the blade 8; the aspirator 7 is hollow inside, and the bottom is equipped with the gas pocket, the one end of aspirator 7 is equipped with the vacuum pump connecting piece, the other end and aspirator hoisting device fixed connection.
The aspirator lifting device is fixedly connected with the aspirator 7 and is used for driving the aspirator to move up and down; the aspirator lifting device comprises a first conveyor belt 16, an upper connecting rod 26, a lower connecting rod 26, a second motor 21 and two first rotating shafts 18 which are respectively arranged at the upper end and the lower end of the upper connecting rod 26, wherein the first conveyor belt 16 is connected between the two first rotating shafts 18, and the other end of the aspirator 7 is fixedly connected with the first conveyor belt 16; the second motor 21 is connected to any one of the first rotating shafts 18 to drive the first conveyor belt 16 to rotate.
The aspirator moving device is fixedly connected with the aspirator lifting device and is used for driving the aspirator lifting device to move left and right; aspirator mobile device includes two parallel arrangement's vertical branch 17, sets up horizontal branch 19 between vertical branch 17, controls conveying pole 27, third motor 20, about, conveying pole 27 is located the below of horizontal branch 19, and one end is connected on vertical branch 17, the other end and upper and lower connecting rod 26 swing joint, third motor 20 with control conveying pole 27 and be connected, conveying pole 27 rotates about the drive, drives about connecting rod 26 prolong about conveying pole 27 direction and controls and remove.
The film unfolding device comprises a second conveyor belt 14, two second rotating shafts 13 and a fourth motor 15, wherein the two second rotating shafts 13 are arranged on the lifting base and are respectively positioned at the front end and the rear end of the lifting base, the second conveyor belt 14 is arranged between the two second rotating shafts 13, the fourth motor 15 is connected with any one of the second rotating shafts 13, and the second conveyor belt 14 is provided with a film unfolding box 10;
the slide display device further comprises a display platform 31, a slide glass platform 29 for placing a slide glass 28 and a first manipulator 30, wherein the display platform 31 is fixed on the side wall of the lifting base 11 and is flush with the second conveyor belt 14 on the lifting base 11; the film spreading platform 31 and the second conveyor 14 are provided with a first film spreading box station 32, a second film spreading box station 33, a third film spreading box station 34 and a fourth film spreading box station 35, the seventh motor 38 is arranged at the second film spreading box station 33 and used for pushing the film spreading boxes on the second film spreading box station 33 to the third film spreading box station 34, the sixth motor 37 is arranged at the third film spreading box station 34 and used for pushing the film spreading boxes on the third film spreading box station 34 to the fourth film spreading box station 35, and the fifth motor 36 is arranged at the fourth film spreading box station 35 and used for pushing the film spreading boxes on the fourth film spreading box station 35 to the first film spreading box station 32; the first robot 30 is mounted adjacent the slide platform 29 for drawing and carrying slides into a cassette at a first cassette station 32.
The upper connecting rod 26 and the lower connecting rod 26 are provided with through holes, threads are arranged in the through holes, threads are arranged on the surfaces of the left conveying rod 27 and the right conveying rod 27, the other ends of the left conveying rod 27 and the right conveying rod 27 penetrate through the through holes in the upper connecting rod 26 and the lower connecting rod 26, and the left conveying rod and the lower connecting rod are connected through.
And the lifting rod 23 is provided with a damping device 24 which is positioned above the fifth motor 25.
Still include 4 lifting pedestal dead levers 12, four lifting pedestal dead levers 12 are located lifting pedestal's position of being connected with second axis of rotation 13 respectively all around.
The shown piece dragging machine comprises a piece dragging device supporting rod 48, a third rotating shaft is arranged between the two parallel piece dragging device supporting rods 48, a third conveying belt 50 is arranged between the two third rotating shafts, and a second mechanical arm 49 is arranged on any one piece dragging device supporting rod 48.
The structure of the second manipulator 49 is the same as that of the first manipulator 30, and a tenth motor 51 is arranged on a vertical sliding rod of the second manipulator 49 and used for controlling the cross arm to move up and down; an eleventh motor 52 is arranged on the trailing arm of the second manipulator 49 and used for controlling the sliding of the sliding piece in the trailing arm. The second manipulator 49 is used for taking out the slide glass in the slide box on the second slide box station 33 and placing the slide glass on the third conveyor belt 50.
Any one of the third rotating shafts is connected with a twelfth motor 53 for controlling the rotating shafts to rotate.
The sheet arranging machine comprises a bottom plate 1, a conveying device for conveying glass slides, namely a third conveying belt 50, a sheet arranging box 55, a sheet pushing device 54, a sheet pushing device supporting rod 56, a thirteenth motor 57 and a fourteenth motor 58, wherein the sheet arranging box 55 is arranged on one side of the conveying belt, and the sheet pushing device supporting rod 56 is arranged on the other side of the conveying belt and is opposite to the position of the sheet arranging box 55; the piece pushing device supporting rod 56 is provided with a thirteenth motor 57, the thirteenth motor 57 is connected with the piece pushing device 54, a through hole is formed in the bottom plate 1 below the whole piece box 55, and a fourteenth motor 58 is arranged at the through hole and used for pushing the whole piece box 55 upwards.
In a further preferred scheme, the sheet integrating machine is respectively provided with a first sheet integrating box station 63, a second sheet integrating box station, a third sheet integrating box station 61 and a fourth sheet integrating box station 62, the fourth sheet integrating box station 62 is positioned on a sheet integrating box platform 64, the third sheet integrating box station 61 is flush with the fourth sheet integrating box station 62, and a sixteenth motor 60 is arranged on one side of the third sheet integrating box station 61 and used for pushing the sheet integrating box on the third sheet integrating box station 61 to the fourth sheet integrating box station 62; the second full-sheet box station is positioned below the third full-sheet box station 61, and a fourteenth motor 58 is arranged below the second full-sheet box station and is used for pushing the full-sheet box on the second full-sheet box station upwards to the third full-sheet box station 61; the first one-piece box station 63 is located behind the second one-piece box station, and a fifteenth motor 59 is arranged behind the first one-piece box station 63 and used for pushing the empty one-piece box into the second one-piece box station.
In a further preferred scheme, the top ends and the bottom ends of the upper connecting rod and the lower connecting rod are movably connected with the upper transverse supporting rod and the lower transverse supporting rod respectively. The concrete swing joint scheme is preferred, the lower surface of the transverse supporting rod located above is provided with a sliding rail, the upper surface of the transverse supporting rod located below is provided with a sliding rail b, the top end and the bottom end of the upper connecting rod and the lower connecting rod are respectively provided with a sliding device matched with the sliding rail, and the upper connecting rod and the lower connecting rod are connected between the upper transverse supporting rod and the lower transverse supporting rod through the sliding devices. The mode of movably connecting the upper connecting rod and the lower connecting rod between the upper transverse supporting rod and the lower transverse supporting rod has a more stable structure.
Description of the working process:
1. the embedded and molded pathological tissue wax block 1 is placed in a pathological tissue placing frame 3, and a pathological tissue wax block 5 is fixed by utilizing an adjusting stud 4; a toughening agent can be added into the wax block for embedding pathological tissues to increase the toughness of the section.
2. A slide way 22 is arranged below the pathological tissue placing frame 3, and the pathological tissue wax block can be regulated to move back and forth on the base through a first motor 6 to be sliced; after each slice is cut, the lifting rod is controlled by the fifth motor 25 to move downwards for a certain displacement, so that the next slice is convenient.
3. Aspirator 7 one end links to each other with outside vacuum pump, the other end is fixed to on first conveyer belt 16, open the vacuum pump, attract the pathological section of pathological tissue wax stone 5, drive first conveyer belt 16 through second motor 21 and upwards pull the motion, conveying rod 27 rotates about the drive of third motor 20 again, thereby drive aspirator hoisting device and remove about whole, with the section of pathological tissue wax stone 5 conveying in the exhibition box top of 32 on first exhibition box station completely, tile again in the box (at this moment the suction type manipulator has inhaled the slide glass in the exhibition box on first exhibition box station 32.
4. The first conveyor belt 16 conveys the slide cassettes on the first slide cassette station 32 to the second slide cassette station 33, and at this time, the slides in the slide cassettes on the second slide cassette station 33 are taken away by manual or other machine type equipment and enter the next procedure for taking out the slides.
5. The seventh motor starts, on pushing away the empty exhibition box fortune on the second exhibition box station 33 to third exhibition box station 34, sixth motor 37 starts again, it pushes away the empty exhibition box fortune on the third exhibition box station 34 to fourth exhibition box station 35, first manipulator puts into the exhibition box in the fourth exhibition box station 35 with the slide glass, fifth motor 36 starts, the exhibition box propelling movement that will put the slide glass is to first exhibition box station 32, aspirator 7 has inhaled pathological section to first exhibition box station 32 top this moment, place on the slide glass, so circulate, realize automatic section and exhibition piece.
6. The second manipulator 49 is used for fishing out the glass slides in the slide boxes on the second slide box station 33 and placing the glass slides on the third conveyor belt 50, and the twelfth motor 53 is used for controlling the conveying speed of the third conveyor belt 50 and conveying the fished glass slides to the subsequent whole-piece process, so that the automatic slide fishing function is realized.
7. The third conveyor belt 50 conveys the slide glass to the front position of the whole sheet box 55, the thirteenth motor 57 is started to push the sheet pusher 54 to push the slide glass into one grid of storage grooves in the whole sheet box 55, the fourteenth motor 58 is started to move the whole sheet box 55 upwards for one grid, and the steps are repeated to realize the automatic storage of the slide glass.
8. Furthermore, a plurality of integral box stations can be provided, the integral machine is respectively provided with a first integral box station 63, a second integral box station, a third integral box station 61 and a fourth integral box station 62, the fourth integral box station 62 is positioned on an integral box platform 64, the third integral box station 61 is flush with the fourth integral box station 62, and a sixteenth motor 60 is arranged on one side of the third integral box station 61 and used for pushing the integral box on the third integral box station 61 to the fourth integral box station 62; the second full-sheet box station is positioned below the third full-sheet box station 61, and a fourteenth motor 58 is arranged below the second full-sheet box station and is used for pushing the full-sheet box on the second full-sheet box station upwards to the third full-sheet box station 61; the first one-piece box station 63 is located behind the second one-piece box station, and a fifteenth motor 59 is arranged behind the first one-piece box station 63 and used for pushing the empty one-piece box into the second one-piece box station. The user only needs to place the empty whole box at the first whole box station 63 and take the empty whole box away after the whole box is fully filled and reaches the fourth whole box station 62.
The above description is for the purpose of illustrating the present invention and is not intended to limit the scope of the present invention, and any person skilled in the art can substitute or change the technical solution of the present invention and its conception within the technical scope of the present invention, and the technical solution and the concept of the present invention are also intended to be covered by the scope of the claims of the present invention.
Claims (10)
1. A pathological section display slice fishing and arranging machine comprises a bottom plate (1), and is characterized by also comprising a slicing mechanism, a slice displaying mechanism, a slice fishing machine and an arranging machine which are arranged on the bottom plate (1);
the slicing mechanism comprises a bottom plate (1), a base (2) arranged on the bottom plate (1) and a pathological tissue placing frame (3) connected with the base (2) in a sliding manner, wherein at least one adjusting stud (4) is arranged on the side wall of the pathological tissue placing frame (3) and used for fixing a wax block (5) of the pathological tissue; the front end of the pathological tissue placing frame (3) is connected with a first motor (6) which is used for pushing the pathological tissue placing frame (3) to move back and forth on the slide way (5); the lifting device is characterized by further comprising a lifting base (11), a lifting rod (23) is arranged at the bottom of the lifting base (11), the lifting rod (23) is connected with a fifth motor (25), the fifth motor (25) is used for driving the lifting rod (23) to move up and down, and the fifth motor (25) is connected with the bottom plate (1); a blade holder (9) is arranged at the front end of the lifting base (11), and a blade (8) is arranged on the blade holder (9);
the sheet unfolding mechanism comprises an aspirator (7), an aspirator lifting device, an aspirator moving device and a sheet unfolding device;
the aspirator (7) is used for sucking up the sliced pathological tissue slices, and the aspirator (7) is arranged above the blade (8);
the aspirator lifting device is fixedly connected with the aspirator (7) and is used for driving the aspirator to move up and down;
the aspirator moving device is fixedly connected with the aspirator lifting device and is used for driving the aspirator lifting device to move left and right;
the film spreading device comprises a second conveyor belt (14), two second rotating shafts (13) and a fourth motor (15), wherein the two second rotating shafts (13) are arranged on the lifting base and are respectively positioned at the front end and the rear end of the lifting base, the second conveyor belt (14) is arranged between the two second rotating shafts (13), the fourth motor (15) is connected with any one of the second rotating shafts (13), and a film spreading box (10) is arranged on the second conveyor belt (14);
the piece fishing machine comprises piece fishing device supporting rods (48), a third rotating shaft is arranged between the two parallel piece fishing device supporting rods (48), a third conveying belt (50) is arranged between the two third rotating shafts, and a second mechanical arm (49) is arranged on any one piece fishing device supporting rod (48); the second manipulator (49) is used for fishing out the glass slides in the slide display boxes on the second slide display box station (33) and placing the glass slides on the third conveyor belt (50); the third conveyor belt (50) is connected with the sheet-forming machine;
the sheet arranging machine comprises a sheet arranging box (55), a sheet pushing device (54), a sheet pushing device supporting rod (56), a thirteenth motor (57) and a fourteenth motor (58), wherein the sheet arranging box (55) is arranged on one side of a third conveyor belt (50), and the sheet pushing device supporting rod (56) is arranged on the other side of the third conveyor belt (50) and is opposite to the sheet arranging box (55); the piece pushing device is characterized in that a thirteenth motor (57) is arranged on the piece pushing device supporting rod (56), the thirteenth motor (57) is connected with the piece pushing device (54), a through hole is formed in the bottom plate (1) below the whole piece box (55), and a fourteenth motor (58) is arranged at the hole and used for pushing the whole piece box (55) upwards.
2. The pathological section, spreading and fishing machine according to claim 1, wherein the aspirator (7) is hollow, the bottom of the aspirator is provided with an air hole (c), one end of the aspirator (7) is provided with a vacuum pump connecting piece (a), and the other end of the aspirator is fixedly connected with an aspirator lifting device.
3. The pathological section spreading and fishing slicing machine as claimed in claim 1, wherein the aspirator lifting device comprises a first conveyor belt (16), an upper connecting rod (26), a lower connecting rod (26), a second motor (21) and two first rotating shafts (18) respectively arranged at the upper end and the lower end of the upper connecting rod (26) and the lower connecting rod (26), the first conveyor belt (16) is connected between the two first rotating shafts (18), one end of the aspirator (7) is provided with a vacuum pump connecting piece, and the other end of the aspirator is fixedly connected with the first conveyor belt (16); the second motor (21) is connected with any one first rotating shaft (18) to drive the first conveyor belt (16) to rotate.
4. The pathological section exhibition piece drags for piece integer machine according to claim 1, characterized by, aspirator mobile device includes two parallel arrangement's vertical branch (17), sets up horizontal branch (19) between vertical branch (17), controls transfer bar (27), third motor (20), control transfer bar (27) and be located the below of horizontal branch (19), and one end is connected on vertical branch (17), and the other end is connected with upper and lower connecting rod (26) swing joint, third motor (20) are connected with about transfer bar (27), and transfer bar (27) are rotated about the drive, and the direction is moved about transfer bar (27) is controlled in the extension of connecting rod (26) about the drive.
5. The pathological section, slide displaying and scooping full-length machine according to claim 1, wherein the slide displaying device further comprises a slide displaying platform (31), a slide displaying platform (29) for placing a slide (28) and a first manipulator (30), the slide displaying platform (31) is fixed on the side wall of the lifting base (11) and is flush with the second conveyor belt (14) on the lifting base (11); the film spreading platform (31) and the second conveyor belt (14) are provided with a first film spreading box station (32), a second film spreading box station (33), a third film spreading box station (34) and a fourth film spreading box station (35), a seventh motor (38) is arranged at the second film spreading box station (33) and used for pushing a film spreading box on the second film spreading box station (33) to the third film spreading box station (34), a sixth motor (37) is arranged at the third film spreading box station (34) and used for pushing the film spreading box on the third film spreading box station (34) to the fourth film spreading box station (35), and a fifth motor (36) is arranged at the fourth film spreading box station (35) and used for pushing the film spreading on the fourth film spreading box station (35) to the first film spreading box station (32); the first manipulator (30) is fixed beside the slide platform (29) and is used for sucking and carrying the slide into the slide box on the first slide box station (32).
6. The pathological section, exhibition and salvage slice whole machine of claim 5, wherein N exhibition boxes are arranged among the first exhibition box station (32), the second exhibition box station (33), the third exhibition box station (34) and the fourth exhibition box station (35), and N is more than or equal to 0.
7. The pathological section spreading and fishing slicer as claimed in claim 5, wherein the first manipulator (30) comprises a vertical fixing rod (42), a vertical sliding rod (41), a cross arm (44) connected between the vertical fixing rod (42) and the vertical sliding rod (41), and a longitudinal arm (43) crossed with the cross arm (44), wherein a sliding rod (46) is arranged in the longitudinal arm (43), the sliding rod penetrates through a sliding part (45), a mechanical arm (47) is connected below the sliding part (45), a suction cup is arranged at the bottom of the mechanical arm, the mechanical arm is hollow inside, and is connected with an external vacuum pump through a hole on the sliding part (45); a ninth motor (40) is arranged on a vertical sliding rod (41) of the first manipulator (30) and used for controlling a cross arm (44) to move up and down; and an eighth motor (39) is arranged on the trailing arm (43) and is used for controlling the sliding piece (45) in the trailing arm to slide.
8. The pathological section spreading and salvaging machine according to claim 7, wherein the structure of the second manipulator (49) is the same as that of the first manipulator (30), and a tenth motor (51) is arranged on a vertical sliding rod of the second manipulator (49) and used for controlling a cross arm to move up and down; an eleventh motor (52) is arranged on the trailing arm of the second manipulator (49) and used for controlling the sliding of the sliding piece in the trailing arm.
9. The pathological section, slice spreading and fetching flaking machine according to claim 1, characterized in that the flaking machine is respectively provided with a first flaking box station (63), a second flaking box station, a third flaking box station (61) and a fourth flaking box station (62), the fourth flaking box station (62) is positioned on a flaking box platform (64), the third flaking box station (61) is flush with the fourth flaking box station (62), and a sixteenth motor (60) is arranged on one side of the third flaking box station (61) and used for pushing the flaking box on the third flaking box station (61) to the fourth flaking box station (62); the second whole-piece box station is positioned below the third whole-piece box station (61), and a fourteenth motor (58) is arranged below the second whole-piece box station and used for pushing the whole-piece boxes on the second whole-piece box station upwards to the third whole-piece box station (61); the first integral box station (63) is located behind the second integral box station, and a fifteenth motor (59) is arranged behind the first integral box station (63) and used for pushing the empty integral box into the second integral box station.
10. The pathological section spreading and scooping slicing machine as claimed in claim 1, wherein the lifting rod (23) is provided with a damping device (24), and the damping device (24) is located above the fifth motor (25).
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| CN201911015477.6A CN110618008B (en) | 2019-10-24 | 2019-10-24 | Pathological section exhibition piece drags for piece integer machine |
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| CN201911015477.6A CN110618008B (en) | 2019-10-24 | 2019-10-24 | Pathological section exhibition piece drags for piece integer machine |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111190277A (en) * | 2020-03-10 | 2020-05-22 | 倪威武 | Medical inspection slide glass safety processing apparatus |
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