CN110613079A - Plum syrup effervescent tablet and preparation method thereof - Google Patents

Plum syrup effervescent tablet and preparation method thereof Download PDF

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Publication number
CN110613079A
CN110613079A CN201911098742.1A CN201911098742A CN110613079A CN 110613079 A CN110613079 A CN 110613079A CN 201911098742 A CN201911098742 A CN 201911098742A CN 110613079 A CN110613079 A CN 110613079A
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China
Prior art keywords
parts
plum
granules
portions
effervescent tablet
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CN201911098742.1A
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Chinese (zh)
Inventor
胡晓娟
刘洪生
王龙霞
李跃克
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Bokai Pharmaceutical Co Ltd
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Bokai Pharmaceutical Co Ltd
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Priority to CN201911098742.1A priority Critical patent/CN110613079A/en
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/385Concentrates of non-alcoholic beverages
    • A23L2/39Dry compositions
    • A23L2/395Dry compositions in a particular shape or form
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/40Effervescence-generating compositions
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention provides a plum syrup effervescent tablet and a preparation method thereof, relating to the technical field of effervescent tablets, wherein the plum syrup effervescent tablet comprises the following raw materials in parts by weight: 800 portions of plum fruit 200-. The effervescent tablet is convenient for carrying, and can be dissolved to obtain plum juice with good taste.

Description

Plum syrup effervescent tablet and preparation method thereof
Technical Field
The invention relates to the technical field of effervescent tablets, in particular to a plum syrup effervescent tablet and a preparation method thereof.
Background
The plum syrup is a traditional summer-heat relieving beverage, has the characteristics of removing oil and greasiness, stimulating appetite and tonifying spleen and good taste, can remove diseases and keep healthy and strong after being drunk frequently, can prevent a drinker from ingesting excessive sugar, and is a rare health-care beverage in hot summer. However, the current plum syrup belongs to decoction and is inconvenient to carry.
In view of the above, the present invention is particularly proposed.
Disclosure of Invention
The invention aims to provide a plum syrup effervescent tablet which is convenient to carry, short in disintegration time and stable in property, and can obtain a plum syrup with good taste after being dissolved.
The invention provides a plum syrup effervescent tablet which comprises the following raw materials in parts by weight:
800 portions of plum fruit 200-.
Further, the feed comprises the following raw materials in parts by weight:
400 portions of plum fruit, 480 portions of hawthorn fruit, 80 portions to 180 portions of Chinese date, 15 portions to 70 portions of menthol, 30 portions to 90 portions of passion fruit, 1850 portions of citric acid, and 490 portions of sodium carbonate, 410.
Further, the feed comprises the following raw materials in parts by weight:
600 parts of smoked plum 450-.
Further, the material also comprises at least one of the following raw materials:
lactose, glucose, maltodextrin, magnesium stearate, flavors, and sweeteners;
preferably, the feed also comprises at least one of the following raw materials in parts by weight: 50-200 parts of lactose, 100 parts of glucose, 50-300 parts of maltodextrin, 10-40 parts of magnesium stearate, 5-50 parts of essence and 5-50 parts of sweetener;
preferably, the sweetener comprises at least one of sucralose, thaumatin, and stevioside.
A method for preparing the plum syrup effervescent tablet comprises the following steps:
mixing the raw materials and tabletting to obtain the plum syrup effervescent tablet.
Further, comprising:
a) mixing hawthorn, jujube, sodium carbonate and part of smoked plum according to the formula amount, and performing first granulation to obtain first granules;
b) mixing citric acid with the rest of the smoked plum in the formula amount, and performing second granulation to obtain second granules;
c) mixing the passion fruit, the menthol, the first granules and the second granules, and tabletting to obtain the plum syrup effervescent tablet.
Further, step a) comprises the steps of:
mixing hawthorn, jujube, sodium carbonate, part of plum in formula amount and a first adhesive, and performing wet granulation to obtain a first wet granule;
sequentially performing first drying and first granulation on the first wet granules to obtain the first granules;
preferably, the first binder comprises ethanol in a volume fraction of 80-95%;
preferably, the temperature of the first drying is 50-70 ℃;
preferably, the first drying time is 1 to 3 hours;
preferably, the first wet granules after drying have a water content of less than 5%;
preferably, the first granulation is performed using a 16 or 18 mesh sieve;
preferably, the hawthorn, the jujube, the sodium carbonate, the lactose, the sweetener and a part of the formula amount of the plum are mixed with the first adhesive and then wet-granulated to obtain a first wet granule.
Further, step b) comprises the steps of:
mixing citric acid, the remaining formula amount of smoked plum and a second adhesive, and performing wet granulation to obtain a second wet granule;
sequentially performing second drying and second granulation on the second wet granules to obtain second granules;
preferably, the second binder comprises 85-95% by volume of ethanol;
preferably, the temperature of the second drying is 50-70 ℃;
preferably, the second drying time is 1 to 3 hours;
preferably, the second granulation is performed using a 16 or 18 mesh sieve;
preferably, the citric acid, the glucose, the maltodextrin and the remaining formula amount of the plum are mixed with the second binder and then subjected to wet granulation to obtain a second wet granule.
Further, step c) comprises the steps of:
mixing passion fruit and menthol with the first granules, then mixing with the second granules, and tabletting to obtain the plum syrup effervescent tablet;
preferably, the essence, the passion fruit, the menthol and the magnesium stearate are mixed with the first granule, then mixed with the second granule, and finally tableted;
preferably, the manner in which the flavor, passion fruit, menthol and magnesium stearate are mixed with the first granules comprises: respectively adding essence, passion fruit, menthol and magnesium stearate into the first granules by adopting an equivalent progressive method;
preferably, the essence, the passion fruit, the menthol and the magnesium stearate are mixed with the first granule, then mixed with the second granule for 25-35 minutes, and finally tabletted.
Further, part of the formula amount of the smoked plums in the step a) is half of the formula amount of the smoked plums;
preferably, the moisture content during tabletting is 40% or less, preferably 20% or less.
Compared with the prior art, the invention can at least obtain the following beneficial effects:
the raw materials in the plum juice effervescent tablet are matched with each other, so that the plum juice effervescent tablet is shorter in disintegration time and more suitable in pH value, is convenient to carry, is good in tablet shape and taste, has the functions of appetizing and tonifying spleen, is free of sticking, is uniform in solution after being dissolved, is more relieved for a drinker, is better in stability, and can keep constant weight and better taste for a longer time.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the following embodiments, and it should be understood that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In one aspect of the invention, the invention provides a plum syrup effervescent tablet, which comprises the following raw materials in parts by weight: 200-800 parts (for example, 200 parts, 400 parts, 600 parts or 800 parts, etc.) of smoked plum, 100-500 parts (for example, 100 parts, 200 parts, 300 parts, 400 parts or 500 parts, etc.) of hawthorn, 50-200 parts (for example, 50 parts, 100 parts, 150 parts or 200 parts, etc.) of jujube, 10-100 parts (for example, 10 parts, 20 parts, 40 parts, 60 parts, 80 parts or 100 parts, etc.) of menthol, 20-100 parts (for example, 20 parts, 40 parts, 60 parts, 80 parts or 100 parts, etc.) of passion fruit, 1600-1900 parts (for example, 1600 parts, 1700 parts, 1800 parts or 1900 parts, etc.) of citric acid, and 400-500 parts (for example, 400 parts, 420 parts, 440 parts, 460 parts, 480 parts or 500 parts, etc.) of sodium carbonate.
The raw materials in the plum juice effervescent tablet are matched with each other, so that the plum juice effervescent tablet is shorter in disintegration time and more suitable in pH value, is convenient to carry, is good in tablet shape and taste, has the functions of appetizing and tonifying spleen, is free of sticking, is uniform in solution after being dissolved, is more relieved for a drinker, is better in stability, and can keep constant weight and better taste for a longer time. The raw materials can achieve due effects only within the proportion range, and if the proportion of the plum or the hawthorn is too low or too high, the plum or the hawthorn can not achieve the optimal effect on strengthening spleen and stimulating appetite; if the proportion of the smoked plum, the hawthorn and the red date is too high, the large-scale production and the disintegration time of the tablets have poor results.
It should be noted that the smoked plum, the hawthorn, the date, the menthol and the passion fruit can be provided in the form of powder, such as smoked plum powder, hawthorn powder, date powder, menthol powder and passion fruit powder, and the date can be red date and the like.
In some preferred embodiments of the present invention, the plum juice effervescent tablet comprises the following raw materials in parts by weight: 400 portions of plum fruit, 480 portions of hawthorn fruit, 80 portions to 180 portions of Chinese date, 15 portions to 70 portions of menthol, 30 portions to 90 portions of passion fruit, 1850 portions of citric acid, and 490 portions of sodium carbonate, 410.
In some more preferred embodiments of the present invention, the plum juice effervescent tablet comprises the following raw materials in parts by weight: 600 parts of smoked plum 450-.
In some embodiments of the present invention, the plum juice effervescent tablet further comprises at least one of the following raw materials: lactose, glucose, maltodextrin, magnesium stearate, flavors, and sweeteners. Therefore, the taste or tablet shape of the plum syrup effervescent tablet is further facilitated.
In some preferred embodiments of the present invention, the plum juice effervescent tablet further comprises at least one of the following raw materials in parts by weight: 50-200 parts (for example, 50 parts, 100 parts, 150 parts, 200 parts, etc.), 100 parts (for example, 100 parts, 200 parts, 300 parts, 400 parts, 500 parts, etc.) of glucose, 50-300 parts (for example, 50 parts, 100 parts, 150 parts, 200 parts, 250 parts, 300 parts, etc.), 10-40 parts (for example, 10 parts, 20 parts, 30 parts, 40 parts, etc.), 5-50 parts (for example, 5 parts, 10 parts, 20 parts, 30 parts, 40 parts, 50 parts, etc.), and 5-50 parts (for example, 5 parts, 10 parts, 20 parts, 30 parts, 40 parts, 50 parts, etc.) of magnesium stearate, and 5-50 parts (for example, 5 parts, 10 parts, 20 parts, 30 parts, 40 parts, 50 parts, etc.) of a sweetener.
In some embodiments of the invention, the sweetener comprises at least one of sucralose, thaumatin, and stevioside.
In another aspect of the present invention, the present invention provides a method for preparing the aforementioned plum juice effervescent tablet, comprising: mixing the raw materials and tabletting to obtain the plum syrup effervescent tablet.
In some embodiments of the present invention, a method for preparing a plum juice effervescent tablet includes:
a) mixing fructus crataegi, fructus Jujubae, sodium carbonate and part of fructus mume with formula amount, and performing first granulation to obtain first granule.
It should be noted that the hawthorn, the date, the sodium carbonate and the smoked plum are consistent with the foregoing description, and redundant description is omitted here.
In some embodiments of the invention, step a) comprises the steps of: mixing hawthorn, jujube, sodium carbonate, part of plum in formula amount and a first adhesive, and performing wet granulation to obtain a first wet granule; the first wet granules are subjected to first drying and first granulation in this order to obtain the first granules.
In some embodiments of the invention, the first binder comprises ethanol in a volume fraction of 80-95%. Therefore, the raw materials are bonded together, and the raw materials are easy to remove during subsequent drying.
In some embodiments of the invention, the temperature of the first drying is 50 to 70 ℃; the time of the first drying is 1 to 3 hours. Therefore, the drying effect is better.
In some embodiments of the invention, the first wet granules after drying have a water content of less than 5%.
The water content refers to the mass percentage of water in the first wet granules after the first drying.
In some embodiments of the invention, the first granulation is performed using a 16 or 18 mesh sieve.
In some preferred embodiments of the present invention, hawthorn, jujube, sodium carbonate, lactose, a sweetener, and a portion of the formulated amount of smoked plum are mixed with a first binder and then wet granulated to obtain a first wet granule. Therefore, the plum syrup effervescent tablets with better mouthfeel can be obtained.
In some preferred embodiments of the present invention, the amount of the prune in step a) is half of the amount of the prune.
b) Mixing citric acid with the rest of the smoked plum in the formula amount, and performing second granulation to obtain a second granule.
It should be noted that citric acid is consistent with the foregoing description and will not be described in too much detail herein.
In some embodiments of the invention, step b) comprises the steps of: mixing citric acid, the remaining formula amount of smoked plum and a second adhesive, and performing wet granulation to obtain a second wet granule; and subjecting the second wet granules to second drying and second granulation in this order to obtain the second granules.
In some embodiments of the invention, the second binder comprises 85-95% ethanol by volume fraction. Therefore, the raw materials are bonded together, and the raw materials are easy to remove during subsequent drying.
In some embodiments of the invention, the temperature of the second drying is 50 to 70 ℃; the time of the second drying is 1 to 3 hours.
In some embodiments of the invention, the second granulation is performed using a 16 or 18 mesh sieve.
In some preferred embodiments of the present invention, the second wet granules are obtained by wet granulation after mixing citric acid, glucose, maltodextrin and the remaining formulation amount of smoked plum with the second binder.
c) Mixing the passion fruit, the menthol, the first granules and the second granules, and tabletting to obtain the plum syrup effervescent tablet.
In some embodiments of the invention, step c) comprises the steps of: mixing the passion fruit and the menthol with the first granules, then mixing with the second granules, and tabletting to obtain the plum syrup effervescent tablet.
In some preferred embodiments of the present invention, the flavor, passion fruit, menthol and magnesium stearate are mixed with the first granule, then mixed with the second granule, and then tableted.
In some preferred embodiments of the present invention, the manner in which the flavor, passion fruit, menthol and magnesium stearate are mixed with the first granules comprises: the essence, the passion fruit, the menthol and the magnesium stearate are respectively added into the first granule by adopting an equivalent progressive method. Therefore, the raw materials are easily and uniformly mixed by adopting an equal-quantity increasing method.
In some preferred embodiments of the present invention, the flavor, passion fruit, menthol and magnesium stearate are mixed with the first granule and then mixed with the second granule for 25-35 minutes (e.g., 25 minutes, 30 minutes, 35 minutes, etc.), followed by tableting.
In some embodiments of the invention, the moisture content of the tablet is less than or equal to 40% (e.g., 5%, 10%, 20%, 30%, 40%, etc.). Thus, the compressed tablets are of higher quality. In some embodiments of the invention, the moisture content during tableting is 20% or less (e.g. 5%, 10%, 20%), the tablet does not absorb any moisture at all, the tablet face is particularly dry and does not stick, but in some embodiments of the invention, the moisture content during tableting is 20% or less, based on which the color of the tablet face is slightly darker without low-level drying of the tablet face at a moisture content of more than 20% (e.g. 30%, 40%), but the quality is not compromised overall.
In some embodiments of the present invention, a method for preparing an effervescent tablet of plum juice comprises the steps of:
(a) uniformly mixing hawthorn powder, red date powder, sodium carbonate, lactose, a sweetening agent and half of the formula amount of plum powder, then adding 80-95% ethanol solution, uniformly mixing, performing wet granulation to prepare first wet granules, drying the first wet granules at 50-70 ℃, wherein the drying time is 1-3 hours, so that the moisture content is less than 5% after the ethanol solution is completely evaporated, and then finishing granules by using a 16-mesh sieve to obtain first granules;
(b) uniformly mixing citric acid, glucose, maltodextrin and half of the formula amount of plum powder, then adding 85-95% ethanol solution, uniformly mixing, performing wet granulation to obtain a first wet granule, drying the first wet granule at 50-70 ℃, drying for 1-3 hours, completely evaporating the ethanol solution, and sieving with a 16-mesh sieve to obtain a second granule;
(c) and respectively weighing the essence, the passion fruit powder, the menthol powder and the magnesium stearate according to the formula ratio, respectively adding the essence, the passion fruit powder, the menthol powder and the magnesium stearate into the first granules by adopting an equivalent progressive method, then mixing the mixture with the second granules for 30 minutes, and tabletting to obtain the plum syrup effervescent tablet.
Some embodiments of the present invention will be described in detail below with reference to specific examples. The embodiments described below and the features of the embodiments can be combined with each other without conflict.
Examples
Example 1
The plum syrup effervescent tablet comprises the following raw materials in parts by weight:
500 parts of smoked plum powder, 500 parts of hawthorn powder, 80 parts of red date powder, 20 parts of menthol powder, 100 parts of lactose, 200 parts of maltodextrin, 20 parts of passion fruit powder, 30 parts of essence, 30 parts of sucralose, 1800 parts of citric acid, 200 parts of glucose, 500 parts of sodium carbonate and 20 parts of magnesium stearate.
Example 2
The plum syrup effervescent tablet comprises the following raw materials in parts by weight:
600 parts of smoked plum powder, 400 parts of hawthorn powder, 60 parts of red date powder, 20 parts of menthol powder, 100 parts of lactose, 300 parts of maltodextrin, 40 parts of passion fruit powder, 40 parts of essence, 25 parts of sucralose, 5 parts of stevioside, 1700 parts of citric acid, 200 parts of glucose, 500 parts of sodium carbonate and 10 parts of magnesium stearate.
Example 3
The plum syrup effervescent tablet comprises the following raw materials in parts by weight:
400 parts of smoked plum powder, 500 parts of hawthorn powder, 150 parts of red date powder, 20 parts of menthol powder, 100 parts of lactose, 200 parts of maltodextrin, 20 parts of passion fruit powder, 15 parts of essence, 25 parts of sucralose, 5 parts of stevioside, 1900 parts of citric acid, 200 parts of glucose, 450 parts of sodium carbonate and 15 parts of magnesium stearate.
Example 4
The plum syrup effervescent tablet comprises the following raw materials in parts by weight:
800 parts of smoked plum powder, 100 parts of hawthorn powder, 50 parts of red date powder, 100 parts of menthol powder, 100 parts of lactose, 200 parts of maltodextrin, 100 parts of passion fruit powder, 10 parts of essence, 25 parts of sucralose, 5 parts of stevioside, 1800 parts of citric acid, 290 parts of glucose, 400 parts of sodium carbonate and 20 parts of magnesium stearate.
Example 5
The plum syrup effervescent tablet comprises the following raw materials in parts by weight:
700 parts of smoked plum powder, 200 parts of hawthorn powder, 200 parts of red date powder, 30 parts of menthol powder, 150 parts of lactose, 250 parts of maltodextrin, 100 parts of passion fruit powder, 10 parts of essence, 25 parts of sucralose, 10 parts of stevioside, 15 parts of thaumatin, 1600 parts of citric acid, 300 parts of glucose, 400 parts of sodium carbonate and 10 parts of magnesium stearate.
Example 6
The plum syrup effervescent tablet comprises the following raw materials in parts by weight:
200 parts of smoked plum powder, 100 parts of hawthorn powder, 50 parts of red date powder, 10 parts of menthol powder, 20 parts of passion fruit powder, 1600 parts of citric acid, 30 parts of sucralose, 20 parts of thaumatin and 400 parts of sodium carbonate.
Example 7
The plum syrup effervescent tablet comprises the following raw materials in parts by weight:
800 parts of smoked plum powder, 500 parts of hawthorn powder, 200 parts of red date powder, 100 parts of menthol powder, 100 parts of passion fruit powder, 1900 parts of citric acid, 30 parts of sucralose, 30 parts of thaumatin and 500 parts of sodium carbonate.
Comparative example 1
The plum syrup effervescent tablet comprises the following raw materials in parts by weight:
150 parts of smoked plum powder, 250 parts of hawthorn powder, 300 parts of red date powder, 100 parts of menthol powder, 400 parts of lactose, 350 parts of maltodextrin, 200 parts of passion fruit powder, 50 parts of essence, 25 parts of sucralose, 10 parts of stevioside, 15 parts of thaumatin, 1500 parts of citric acid, 292 parts of glucose, 350 parts of sodium carbonate and 8 parts of magnesium stearate.
Comparative example 2
The plum syrup effervescent tablet comprises the following raw materials in parts by weight:
900 parts of smoked plum powder, 100 parts of hawthorn powder, 50 parts of red date powder, 5 parts of menthol powder, 200 parts of lactose, 300 parts of maltodextrin, 100 parts of passion fruit powder, 60 parts of essence, 25 parts of sucralose, 10 parts of stevioside, 45 parts of thaumatin, 1550 parts of citric acid, 300 parts of glucose, 350 parts of sodium carbonate and 5 parts of magnesium stearate.
Comparative example 3
The raw material composition of the plum syrup effervescent tablet is the same as that in example 1, except that the content of citric acid is 2000 parts by weight.
Comparative example 4
The raw material composition of the plum syrup effervescent tablet is the same as that of example 1, except that the content of citric acid is 1400 parts by weight.
Comparative example 5
The raw material composition of the plum syrup effervescent tablet is the same as that in example 1, except that the content of sodium carbonate is 300 parts by weight.
Comparative example 6
The raw material composition of the plum syrup effervescent tablet is the same as that in example 1, except that the content of sodium carbonate is 600 parts by weight.
The plum syrup effervescent tablets of examples 1 to 7 and comparative examples 1 to 6 were prepared using the following method:
(a) uniformly mixing half of the formula amount of plum powder, hawthorn powder, red date powder, sodium carbonate, lactose and a sweetening agent, then adding 90% by volume of ethanol solution, uniformly mixing, carrying out wet granulation to obtain first wet granules, drying the first wet granules at 60 ℃ for 2 hours to ensure that the moisture is less than 5% after the ethanol solution is completely evaporated, and then carrying out granulation by using a 16-mesh sieve to obtain first granules;
(b) uniformly mixing citric acid, glucose, maltodextrin and half of the formula amount of plum powder, then adding 90% ethanol solution by volume fraction, uniformly mixing, performing wet granulation to obtain a first wet granule, drying the first wet granule at 60 ℃ for 2 hours, completely evaporating the ethanol solution, and sieving with a 16-mesh sieve to obtain a second granule;
(c) and respectively weighing the essence, the passion fruit powder, the menthol powder and the magnesium stearate according to the formula ratio, respectively adding the essence, the passion fruit powder, the menthol powder and the magnesium stearate into the first granules by adopting an equivalent progressive method, then mixing the mixture with the second granules for 30 minutes, and tabletting to obtain the plum syrup effervescent tablet.
In the preparation of the plum syrup effervescent tablets of examples 6 to 7 according to the above-mentioned method, the components not mentioned were not added.
The plum syrup effervescent tablets provided in the above examples 1 to 7 and comparative examples 1 to 6 were subjected to performance tests, and the test results are shown in the following table 1:
TABLE 1
As can be seen from Table 1, the plum syrup effervescent tablets provided by the embodiments 1-7 of the present invention have the advantages of good tablet shape, no sticky punch, uniform solution after dissolution, pH value between 3.9-4.1, rapid disintegration, disintegration time of 153-157s, substantially unchanged weight and taste within 3 months, and good stability.
As can be seen from the comparison between examples 1-7 and comparative examples 1-2, when the plum powder, hawthorn powder, red date powder, menthol powder, lactose, maltodextrin, passion fruit powder, essence, sweetener, citric acid, glucose, sodium carbonate and magnesium stearate are in a specific mass part range, the raw materials are cooperated with each other, and the prepared plum juice effervescent tablet is good in tablet shape, free of sticking, uniform in solution after dissolution and more relieved for drinkers.
In addition, the plum syrup effervescent tablets provided in examples 1 to 7 and comparative examples 1 to 2 were subjected to microbiological tests at month 1, month 2 and month 3, respectively, and no microorganism was found.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.

Claims (10)

1. The plum syrup effervescent tablet is characterized by comprising the following raw materials in parts by weight:
800 portions of plum fruit 200-.
2. The plum syrup effervescent tablet of claim 1, comprising the following raw materials in parts by weight:
400 portions of plum fruit, 480 portions of hawthorn fruit, 80 portions to 180 portions of Chinese date, 15 portions to 70 portions of menthol, 30 portions to 90 portions of passion fruit, 1850 portions of citric acid, and 490 portions of sodium carbonate, 410.
3. The plum syrup effervescent tablet of claim 1, comprising the following raw materials in parts by weight:
600 parts of smoked plum 450-.
4. The plum syrup effervescent tablet according to any one of claims 1 to 3, further comprising at least one of the following raw materials:
lactose, glucose, maltodextrin, magnesium stearate, flavors, and sweeteners;
preferably, the feed also comprises at least one of the following raw materials in parts by weight: 50-200 parts of lactose, 100 parts of glucose, 50-300 parts of maltodextrin, 10-40 parts of magnesium stearate, 5-50 parts of essence and 5-50 parts of sweetener;
preferably, the sweetener comprises at least one of sucralose, thaumatin, and stevioside.
5. A method for preparing the plum syrup effervescent tablet of any one of claims 1 to 4, comprising:
mixing the raw materials and tabletting to obtain the plum syrup effervescent tablet.
6. The method of claim 5, comprising:
a) mixing hawthorn, jujube, sodium carbonate and part of smoked plum according to the formula amount, and performing first granulation to obtain first granules;
b) mixing citric acid with the rest of the smoked plum in the formula amount, and performing second granulation to obtain second granules;
c) mixing the passion fruit, the menthol, the first granules and the second granules, and tabletting to obtain the plum syrup effervescent tablet.
7. The method of claim 6, wherein step a) comprises the steps of:
mixing hawthorn, jujube, sodium carbonate, part of plum in formula amount and a first adhesive, and performing wet granulation to obtain a first wet granule;
sequentially performing first drying and first granulation on the first wet granules to obtain the first granules;
preferably, the first binder comprises ethanol in a volume fraction of 80-95%;
preferably, the temperature of the first drying is 50-70 ℃;
preferably, the first drying time is 1 to 3 hours;
preferably, the first wet granules after drying have a water content of less than 5%;
preferably, the first granulation is performed using a 16 or 18 mesh sieve;
preferably, the hawthorn, the jujube, the sodium carbonate, the lactose, the sweetener and a part of the formula amount of the plum are mixed with the first adhesive and then wet-granulated to obtain a first wet granule.
8. The method for preparing according to claim 6 or 7, wherein step b) comprises the steps of:
mixing citric acid, the remaining formula amount of smoked plum and a second adhesive, and performing wet granulation to obtain a second wet granule;
sequentially performing second drying and second granulation on the second wet granules to obtain second granules;
preferably, the second binder comprises 85-95% by volume of ethanol;
preferably, the temperature of the second drying is 50-70 ℃;
preferably, the second drying time is 1 to 3 hours;
preferably, the second granulation is performed using a 16 or 18 mesh sieve;
preferably, the citric acid, the glucose, the maltodextrin and the remaining formula amount of the plum are mixed with the second binder and then subjected to wet granulation to obtain a second wet granule.
9. The method of claim 8, wherein step c) comprises the steps of:
mixing passion fruit and menthol with the first granules, then mixing with the second granules, and tabletting to obtain the plum syrup effervescent tablet;
preferably, the essence, the passion fruit, the menthol and the magnesium stearate are mixed with the first granule, then mixed with the second granule, and finally tableted;
preferably, the manner in which the flavor, passion fruit, menthol and magnesium stearate are mixed with the first granules comprises: respectively adding essence, passion fruit, menthol and magnesium stearate into the first granules by adopting an equivalent progressive method;
preferably, the essence, the passion fruit, the menthol and the magnesium stearate are mixed with the first granule, then mixed with the second granule for 25-35 minutes, and finally tabletted.
10. The method according to claim 6, 7 or 9, wherein the amount of the partially formulated amount of the pickled plum in the step a) is half of the amount of the formulated amount of the pickled plum;
preferably, the moisture content during tabletting is 40% or less, preferably 20% or less.
CN201911098742.1A 2019-11-11 2019-11-11 Plum syrup effervescent tablet and preparation method thereof Pending CN110613079A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104705762A (en) * 2015-03-07 2015-06-17 湖北卫尔康现代中药有限公司 Plum juice effervescent tablet
CN107212232A (en) * 2017-06-19 2017-09-29 苏州市李良济健康产业有限公司 A kind of preparation method of syrup of plum effervescent tablet
CN108815269A (en) * 2018-07-03 2018-11-16 郑州博凯医药保健品有限公司 Folic acid ferrous gluconate vitamin C effervescent tablet and its preparation method and application

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104705762A (en) * 2015-03-07 2015-06-17 湖北卫尔康现代中药有限公司 Plum juice effervescent tablet
CN107212232A (en) * 2017-06-19 2017-09-29 苏州市李良济健康产业有限公司 A kind of preparation method of syrup of plum effervescent tablet
CN108815269A (en) * 2018-07-03 2018-11-16 郑州博凯医药保健品有限公司 Folic acid ferrous gluconate vitamin C effervescent tablet and its preparation method and application

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Application publication date: 20191227