CN110585333A

CN110585333A - Hypertension medicine for nourishing yin and reducing liver fire and preparation method thereof

Info

Publication number: CN110585333A
Application number: CN201910860337.2A
Authority: CN
Inventors: 王兆建
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-09-11
Filing date: 2019-09-11
Publication date: 2019-12-20

Abstract

The invention discloses a hypertension drug for nourishing yin and lowering liver fire and a preparation method thereof, wherein the drug comprises the following components in parts by weight: 10-30 parts of adenophora stricta, 6-25 parts of asparagus, 9-30 parts of radix ophiopogonis, 5-20 parts of rhizoma anemarrhenae, 5-20 parts of cortex phellodendri, 10-25 parts of Chinese yam, 8-30 parts of radix rehmanniae, 10-30 parts of radix paeoniae alba and 6-18 parts of raw liquorice. The hypertension medicine for nourishing yin and lowering liver fire provided by the invention is used for treating liver yang hyperactivity causing hypertension, and is prepared by taking nourishing yin as a main part and combining the effects of tonifying spleen, eliminating dampness and astringing yin, so that the liver fire is lowered, and the blood pressure is lowered along with the liver fire; the hypertension can be basically controlled after continuous taking for a period of time, and no side effect is caused; after a longer period of conditioning, the hypertension is more ideally controlled, and the blood pressure does not rebound, thereby achieving the effect of healing.

Description

Hypertension medicine for nourishing yin and reducing liver fire and preparation method thereof

Technical Field

The invention belongs to the technical field of traditional Chinese medicines, and relates to a hypertension drug for nourishing yin and reducing liver fire and a preparation method thereof.

Background

Hypertension is a common clinical high-incidence disease, has serious harm to important organs such as heart, brain, kidney and the like, is about 2.7 hundred million for patients with hypertension nationwide at present, and is the primary cause of cardiovascular and cerebrovascular diseases. The fatality rate of cardiovascular and cerebrovascular diseases caused by hypertension in China is increased year by year, as for cerebral apoplexy, 160 more than ten thousand people are newly sent out every year in China, about 600 ten thousand people are accumulated as survivors, more than 75% of the survivors lose labor force, 45% of the survivors are severely disabled, and life cannot be managed by self.

Western medicines for treating hypertension lack medicines capable of regulating physique and regulating blood pressure (lowering blood pressure). The pressure reduction treatment in modern medicine is symptomatic treatment. The blood pressure lowering drugs commonly used at present comprise 5 types of Calcium Channel Blockers (CCB), Angiotensin Converting Enzyme Inhibitors (ACEI), angiotensin II receptor blockers (ARB), diuretics and beta blockers, and can not completely prevent the development of hypertension and the secondary diseases thereof. Most of the patients with hypertension need 2 or more antihypertensive medicines to reach the target blood pressure or are difficult to reach the target blood pressure, most of the patients need to take the medicine for life, the curative effect of the medicine is gradually reduced due to long-term administration, toxic and side effects are generated, and the problems are more prominent along with the prolonging of the service life. There is still a pressing need for new and more sophisticated therapeutic agents for the treatment of hypertension.

The existing traditional Chinese medicine conditioning method has certain advantages when being used for treating hypertension, but has serious defects. Especially, hypertension of liver-yang hyperactivity type, yin-deficiency and yang-hyperactivity type, yin-yang deficiency type, wind-phlegm obstruction type and qi-blood upward type causes great pain to patients, and has unstable blood pressure and great side effects.

Disclosure of Invention

The invention aims to solve the technical problem of providing a medicine for nourishing yin and lowering liver fire and a preparation method thereof.

The invention is realized by the following technical scheme:

the hypertension medicine for nourishing yin and reducing liver fire comprises the following components in parts by weight: 10-30 parts of adenophora stricta, 6-25 parts of asparagus, 9-30 parts of radix ophiopogonis, 5-20 parts of rhizoma anemarrhenae, 5-20 parts of cortex phellodendri, 10-25 parts of Chinese yam, 8-30 parts of radix rehmanniae, 10-30 parts of radix paeoniae alba and 6-18 parts of raw liquorice.

Further, the formula comprises: 10-20 parts of adenophora stricta, 10-20 parts of asparagus, 10-20 parts of radix ophiopogonis, 8-12 parts of rhizoma anemarrhenae, 8-12 parts of golden cypress, 10-22 parts of Chinese yam, 8-20 parts of radix rehmanniae, 10-25 parts of radix paeoniae alba and 6-15 parts of raw liquorice.

Further, the formula comprises: 12-18 parts of adenophora stricta, 12-18 parts of asparagus, 10-18 parts of radix ophiopogonis, 10-12 parts of rhizoma anemarrhenae, 10-12 parts of golden cypress, 10-20 parts of Chinese yam, 8-15 parts of radix rehmanniae, 10-20 parts of radix paeoniae alba and 10-15 parts of raw liquorice.

Furthermore, the formula comprises: 15 parts of adenophora stricta, 15 parts of asparagus, 15 parts of radix ophiopogonis, 10-12 parts of rhizoma anemarrhenae, 10-12 parts of phellodendron, 15 parts of Chinese yam, 10 parts of radix rehmanniae, 10-15 parts of radix paeoniae alba and 10-15 parts of raw liquorice.

The invention also provides a preparation method of the hypertension drug for nourishing yin and reducing liver fire, which comprises the following operations:

1) the preparation method comprises the following steps of respectively preparing the following traditional Chinese medicinal materials in parts by mass: 10-30 parts of adenophora stricta, 6-25 parts of asparagus, 9-30 parts of radix ophiopogonis, 5-20 parts of rhizoma anemarrhenae, 5-20 parts of phellodendron, 10-25 parts of Chinese yam, 8-30 parts of radix rehmanniae, 10-30 parts of radix paeoniae alba and 6-18 parts of raw liquorice;

2) soaking the medicinal materials in water for 20-50 min, and decocting for 20-50 min;

3) filtering, collecting decoction, and making into decoction for treating hypertension.

The preparation method of the hypertension medicine for nourishing yin and reducing liver fire comprises the following steps of decocting the medicinal materials for multiple times:

after filtering and collecting decoction, adding water into the medicinal materials again for soaking and decocting; the medicinal materials are decocted for 2-3 times and then the decoction is combined.

The invention also proposes the following applications:

the hypertension drug for nourishing yin and lowering liver fire is applied to the preparation of the medicine for treating hypertension.

The collected decoction is applied to the preparation of the medicine for treating hypertension.

Compared with the prior art, the invention has the following beneficial technical effects:

the hypertension medicine for nourishing yin and lowering liver fire provided by the invention is used for treating liver yang hyperactivity causing hypertension, and is prepared by taking nourishing yin as a main part and combining the effects of tonifying spleen, eliminating dampness and astringing yin, so that the liver fire is lowered, and the blood pressure is lowered along with the liver fire; wherein radix Adenophorae, radix asparagi, radix Ophiopogonis, and radix rehmanniae are effective in nourishing yin; rhizoma Dioscoreae has effects of invigorating spleen and eliminating dampness, and rhizoma anemarrhenae and cortex Phellodendri have effects of guiding fire to the source; especially, after nourishing yin, the white peony root can astringe yin, and finally the raw licorice root can coordinate the effects of the other drugs in the recipe.

The hypertension medicine for nourishing yin and lowering liver fire provided by the invention is prepared by soaking and decocting various medicinal materials into decoction, and is taken after breakfast and supper; generally, after five pairs of medicines are taken, the hypertension symptom is relieved, and the hypertension can be basically controlled after the medicines are taken continuously for a period of time without side effect; after a longer period of conditioning, the hypertension is more ideally controlled, and the blood pressure does not rebound, thereby achieving the effect of healing. The medicine provided by the invention has a plurality of clinical cure cases, the effective time varies from person to person in the taking process, the time of some people is longer, and the time of some people is shorter, but the treatment effect can be achieved.

Detailed Description

The present invention will now be described in further detail with reference to the following examples, which are intended to be illustrative, but not limiting, of the invention.

The invention is based on the following considerations: hypertension is a manifestation of liver-yang hyperactivity, and in order to treat liver-yang hyperactivity, medicines for nourishing yin are used, and spleen invigorating, dampness eliminating and yin astringing are combined for conditioning, so that the liver fire is reduced by guiding fire to the origin, and the blood pressure is reduced after the liver fire is reduced, so that the blood pressure is not high. Therefore, the hypertension drug provided by the invention is prepared by taking yin nourishing as a main material and combining the effects of tonifying spleen, eliminating dampness and astringing yin:

The preparation method of the hypertension medicine for nourishing yin and reducing liver fire comprises the following operations:

The hypertension drug provided by the invention is prepared by taking yin as a main part and combining spleen strengthening, dampness eliminating and yin astringing to guide fire to return to the source so as to reduce liver fire, and the blood pressure is reduced after the liver fire is reduced; wherein radix Adenophorae, radix asparagi, radix Ophiopogonis, and radix rehmanniae are effective in nourishing yin; rhizoma Dioscoreae has effects of invigorating spleen and eliminating dampness, and rhizoma anemarrhenae and cortex Phellodendri have effects of guiding fire to the source; especially, after nourishing yin, the white peony root can astringe yin, and finally the raw licorice root can coordinate the effects of the other drugs in the recipe.

The hypertension medicine for nourishing yin and lowering liver fire provided by the invention is prepared into decoction to be taken after breakfast and supper; in preparation, the medicinal materials are decocted for a plurality of times: after filtering and collecting decoction, adding water into the medicinal materials again for soaking and decocting; the medicinal materials are decocted for 2-3 times and then the decoction is combined. The hypertension drug of the invention generally relieves the hypertension symptom after taking five drugs, can basically control the hypertension after taking for a period of time continuously, and has no side effect; after a longer period of conditioning, the hypertension is more ideally controlled, and the blood pressure does not rebound, thereby achieving the effect of healing.

Specific examples are given below.

Example 1

The hypertension medicine for nourishing yin and reducing liver fire comprises the following components in parts by weight:

10 parts of adenophora stricta, 6 parts of asparagus, 9 parts of dwarf lilyturf tuber, 5 parts of rhizoma anemarrhenae, 5 parts of phellodendron, 10 parts of Chinese yam, 8 parts of radix rehmanniae, 10 parts of white paeony root and 6 parts of raw liquorice.

During preparation, the medicinal materials are soaked in water for 20-50 min and then decocted for 20-50 min; filtering and collecting decoction; after the decoction is collected, the medicinal materials are added with water again for soaking and then decocted; the medicinal materials are decocted for 2-3 times, and then the decoction is combined to prepare the hypertension drug of decoction.

Example 2

30 parts of adenophora stricta, 25 parts of asparagus, 30 parts of dwarf lilyturf tuber, 20 parts of rhizoma anemarrhenae, 20 parts of phellodendron, 25 parts of Chinese yam, 30 parts of radix rehmanniae, 30 parts of white paeony root and 18 parts of raw liquorice.

During preparation, the medicinal materials are soaked in water for 20-50 min (the medicinal materials are submerged in water), and then decocted at 80-100 ℃ for 20-50 min; filtering and collecting decoction; after the decoction is collected, the medicinal materials are added with water again for soaking and then decocted; the medicinal materials are decocted for 2-3 times, and then the decoction is combined to prepare the hypertension drug of decoction.

Example 3

10 parts of adenophora stricta, 10 parts of asparagus, 10 parts of dwarf lilyturf tuber, 8 parts of rhizoma anemarrhenae, 8 parts of phellodendron, 10 parts of Chinese yam, 8 parts of radix rehmanniae, 10 parts of white paeony root and 6 parts of raw liquorice.

Example 4

20 parts of adenophora stricta, 20 parts of asparagus, 20 parts of dwarf lilyturf tuber, 12 parts of rhizoma anemarrhenae, 12 parts of amur corktree bark, 22 parts of Chinese yam, 20 parts of radix rehmanniae, 25 parts of white paeony root and 15 parts of raw liquoric root.

Example 5

12 parts of adenophora stricta, 12 parts of asparagus, 10 parts of dwarf lilyturf tuber, 10 parts of rhizoma anemarrhenae, 10 parts of amur corktree bark, 10 parts of Chinese yam, 8 parts of radix rehmanniae, 10 parts of white paeony root and 10 parts of raw liquoric root.

Example 6

18 parts of adenophora stricta, 18 parts of asparagus, 18 parts of dwarf lilyturf tuber, 12 parts of rhizoma anemarrhenae, 12 parts of amur corktree bark, 20 parts of Chinese yam, 15 parts of radix rehmanniae, 20 parts of white paeony root and 15 parts of raw liquoric root.

Example 7

15 parts of adenophora stricta, 15 parts of asparagus, 15 parts of dwarf lilyturf tuber, 10 parts of rhizoma anemarrhenae, 10 parts of amur corktree bark, 15 parts of Chinese yam, 10 parts of radix rehmanniae, 10 parts of white paeony root and 10 parts of raw liquoric root.

Example 8

15 parts of adenophora stricta, 15 parts of asparagus, 15 parts of dwarf lilyturf tuber, 12 parts of rhizoma anemarrhenae, 12 parts of amur corktree bark, 15 parts of Chinese yam, 10 parts of dried rehmannia root, 15 parts of white paeony root and 15 parts of raw liquoric root.

Specific use examples are given below.

Use example 1: guo of a certain female, 55 years old, Shaanxi baby chicken with symptoms of long-term hypertension accompanied by dizziness and higher hypertension; the hypertension decoction is taken for five months, and the blood pressure is basically controlled.

Use example 2: if a certain plum is a female, the female is 50 years old, and people in the Xian Changan district are diagnosed as hypertension in a hospital, and the hypertension is reduced by taking western medicines; blood pressure rebounds after medicine is stopped; after the decoction for treating hypertension is taken, the decoction can take effect after being taken for one month, and the decoction is stopped after being taken for half a year, so that the blood pressure is stable and does not rebound.

Use example 3: qiangzhi, male, 60 years old, New city people of Western Ann, the symptom is hypertension, coronary heart disease, take Western medicine to lower blood pressure for a long time; blood pressure rebounds after medicine stopping, chest distress and short breath; the hypertension decoction of the invention can be taken for half a year before taking the decoction, and has no coronary heart disease attack and stable blood pressure without rebound; after the medicine is taken for one year, the blood pressure can be kept stable only by taking the medicine intermittently.

Use example 4: wu-chi, male, 70 years old, Shanxi Weinan people, with symptoms of hypertension, takes effect after taking the hypertension decoction of the invention for three months, and keeps stable blood pressure after insisting on taking for half a year.

The above is an example of the present invention in a clinical setting for a wide range of uses.

The invention starts from the main reason of causing hypertension, takes yin nourishing as the main part and combines with spleen strengthening, dampness eliminating and yin astringing for conditioning, and the purpose of reducing liver fire is achieved by leading the fire to return to the source, and the blood pressure is reduced after the liver fire is reduced; the actual treatment effect is obvious.

Therefore, the hypertension drug for nourishing yin and lowering liver fire provided by the invention has the following applications:

The prepared decoction is applied to the preparation of the medicine for treating hypertension.

The embodiments given above are preferable examples for implementing the present invention, and the present invention is not limited to the above-described embodiments. Any non-essential addition and replacement made by the technical characteristics of the technical scheme of the invention by a person skilled in the art belong to the protection scope of the invention.

Claims

1. The hypertension drug for nourishing yin and lowering liver fire is characterized by comprising the following components in parts by weight: 10-30 parts of adenophora stricta, 6-25 parts of asparagus, 9-30 parts of radix ophiopogonis, 5-20 parts of rhizoma anemarrhenae, 5-20 parts of cortex phellodendri, 10-25 parts of Chinese yam, 8-30 parts of radix rehmanniae, 10-30 parts of radix paeoniae alba and 6-18 parts of raw liquorice.

2. The hypertension drug for nourishing yin and lowering liver fire according to claim 1, which comprises the following components in parts by weight: 10-20 parts of adenophora stricta, 10-20 parts of asparagus, 10-20 parts of radix ophiopogonis, 8-12 parts of rhizoma anemarrhenae, 8-12 parts of golden cypress, 10-22 parts of Chinese yam, 8-20 parts of radix rehmanniae, 10-25 parts of radix paeoniae alba and 6-15 parts of raw liquorice.

3. The hypertension drug for nourishing yin and lowering liver fire according to claim 1, which comprises the following components in parts by weight: 12-18 parts of adenophora stricta, 12-18 parts of asparagus, 10-18 parts of radix ophiopogonis, 10-12 parts of rhizoma anemarrhenae, 10-12 parts of golden cypress, 10-20 parts of Chinese yam, 8-15 parts of radix rehmanniae, 10-20 parts of radix paeoniae alba and 10-15 parts of raw liquorice.

4. The hypertension drug for nourishing yin and lowering liver fire according to claim 1, which comprises the following components in parts by weight: 15 parts of adenophora stricta, 15 parts of asparagus, 15 parts of radix ophiopogonis, 10-12 parts of rhizoma anemarrhenae, 10-12 parts of phellodendron, 15 parts of Chinese yam, 10 parts of radix rehmanniae, 10-15 parts of radix paeoniae alba and 10-15 parts of raw liquorice.

5. A preparation method of a hypertension drug for nourishing yin and reducing liver fire is characterized by comprising the following operations:

6. The method for preparing hypertension drug with yin nourishing and liver fire decreasing functions as claimed in claim 1, wherein the herbs are decocted for several times:

7. The use of the antihypertensive agent for nourishing yin to lower liver fire according to claim 1 for the preparation of a medicament for treating hypertension.

8. Use of the decoction collected in claim 5 for the preparation of a medicament for the treatment of hypertension.