CN110575481A - traditional Chinese medicine composition for treating gynecological leucorrhea and preparation method thereof - Google Patents
traditional Chinese medicine composition for treating gynecological leucorrhea and preparation method thereof Download PDFInfo
- Publication number
- CN110575481A CN110575481A CN201910895757.4A CN201910895757A CN110575481A CN 110575481 A CN110575481 A CN 110575481A CN 201910895757 A CN201910895757 A CN 201910895757A CN 110575481 A CN110575481 A CN 110575481A
- Authority
- CN
- China
- Prior art keywords
- parts
- traditional chinese
- chinese medicine
- medicine composition
- leucorrhea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 34
- 239000003814 drug Substances 0.000 title claims abstract description 31
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 29
- 241000132012 Atractylodes Species 0.000 claims abstract description 21
- 244000268590 Euryale ferox Species 0.000 claims abstract description 20
- 235000006487 Euryale ferox Nutrition 0.000 claims abstract description 20
- 241001278833 Rosa laevigata Species 0.000 claims abstract description 20
- 235000000661 Rosa laevigata Nutrition 0.000 claims abstract description 20
- 235000011034 Rubus glaucus Nutrition 0.000 claims abstract description 20
- 235000009122 Rubus idaeus Nutrition 0.000 claims abstract description 20
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 19
- 241000218176 Corydalis Species 0.000 claims abstract description 18
- 241000612118 Samolus valerandi Species 0.000 claims abstract description 18
- 235000014220 Rhus chinensis Nutrition 0.000 claims abstract description 14
- 240000003152 Rhus chinensis Species 0.000 claims abstract description 14
- 241000972672 Phellodendron Species 0.000 claims abstract description 12
- 210000000582 semen Anatomy 0.000 claims abstract description 8
- 240000007651 Rubus glaucus Species 0.000 claims abstract 5
- 239000000706 filtrate Substances 0.000 claims description 20
- 240000007371 Cuscuta campestris Species 0.000 claims description 14
- 238000002156 mixing Methods 0.000 claims description 12
- 238000001914 filtration Methods 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 241000212948 Cnidium Species 0.000 claims description 8
- 239000000829 suppository Substances 0.000 claims description 7
- 238000005303 weighing Methods 0.000 claims description 5
- 241000972673 Phellodendron amurense Species 0.000 claims description 3
- 239000006210 lotion Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 18
- 230000002159 abnormal effect Effects 0.000 abstract description 12
- 244000052769 pathogen Species 0.000 abstract description 5
- 230000001717 pathogenic effect Effects 0.000 abstract description 4
- 208000015181 infectious disease Diseases 0.000 abstract description 3
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 2
- 244000235659 Rubus idaeus Species 0.000 description 15
- 206010012735 Diarrhoea Diseases 0.000 description 10
- 210000000952 spleen Anatomy 0.000 description 9
- 210000003734 kidney Anatomy 0.000 description 8
- 241000218691 Cupressaceae Species 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 206010041497 Spermatorrhoea Diseases 0.000 description 5
- 210000004185 liver Anatomy 0.000 description 5
- 230000004048 modification Effects 0.000 description 5
- 238000012986 modification Methods 0.000 description 5
- 208000003251 Pruritus Diseases 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000027939 micturition Effects 0.000 description 4
- 238000005728 strengthening Methods 0.000 description 4
- 210000001215 vagina Anatomy 0.000 description 4
- 201000004624 Dermatitis Diseases 0.000 description 3
- 208000010668 atopic eczema Diseases 0.000 description 3
- 208000019902 chronic diarrheal disease Diseases 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 208000001848 dysentery Diseases 0.000 description 3
- 230000004438 eyesight Effects 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- 206010000242 Abortion threatened Diseases 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 241000721047 Danaus plexippus Species 0.000 description 2
- 208000008967 Enuresis Diseases 0.000 description 2
- 206010027514 Metrorrhagia Diseases 0.000 description 2
- 206010059013 Nocturnal emission Diseases 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 208000005985 Threatened Abortion Diseases 0.000 description 2
- 206010000210 abortion Diseases 0.000 description 2
- 231100000176 abortion Toxicity 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 208000022531 anorexia Diseases 0.000 description 2
- 235000019606 astringent taste Nutrition 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 206010061428 decreased appetite Diseases 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 206010029410 night sweats Diseases 0.000 description 2
- 230000036565 night sweats Effects 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 229940126673 western medicines Drugs 0.000 description 2
- 206010000234 Abortion spontaneous Diseases 0.000 description 1
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 241000437896 Corydalis bungeana Species 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- 208000015220 Febrile disease Diseases 0.000 description 1
- 208000007984 Female Infertility Diseases 0.000 description 1
- 206010016717 Fistula Diseases 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000037319 Hepatitis infectious Diseases 0.000 description 1
- 206010020741 Hyperpyrexia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010021928 Infertility female Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 206010026749 Mania Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 206010034038 Parotitis Diseases 0.000 description 1
- 208000012287 Prolapse Diseases 0.000 description 1
- 206010037083 Prurigo Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 206010046814 Uterine prolapse Diseases 0.000 description 1
- 208000012886 Vertigo Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 239000003212 astringent agent Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000003756 cervix mucus Anatomy 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 230000002920 convulsive effect Effects 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 230000003890 fistula Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 208000005252 hepatitis A Diseases 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 201000010727 rectal prolapse Diseases 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 210000004706 scrotum Anatomy 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/86—Violaceae (Violet family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Insects & Arthropods (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating gynecological leucorrhea, which comprises the following components in parts by weight: 25-45 parts of phellodendron, 35-45 parts of fructus cnidii, 35-45 parts of bighead atractylodes rhizome, 70-80 parts of semen cuscutae, 20-35 parts of bunge corydalis herb, 15-25 parts of dragon bone, 40-50 parts of Chinese gall, 45-60 parts of raspberry, 75-90 parts of cherokee rose fruit and 10-20 parts of gordon euryale seed. The invention also provides a preparation method of the traditional Chinese medicine composition for treating gynecological leucorrhea. The traditional Chinese medicine composition for treating gynecological leucorrhea provided by the invention can effectively treat abnormal leucorrhea caused by pathogen infection, and has small side effect.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating gynecological leucorrhea and a preparation method thereof.
Background
Leucorrhea is the discharge of vaginal discharge, and it is not only a natural barrier of women, keeps the vagina moist, prevents the invasion of pathogens, and reflects the health of the body.
Abnormal leucorrhea is a common gynecological inflammation, which disturbs many women for a long time, and the common abnormal leucorrhea mainly refers to the change of the amount, color, quality and taste of leucorrhea. At present, aiming at abnormal leucorrhea infected by pathogens, western medicines are mainly used for sterilization to achieve the treatment effect, but beneficial bacteria in the vagina are killed while pathogenic pathogens causing abnormal leucorrhea are killed, the self-cleaning function of the vagina is destroyed, and the western medicines easily cause stimulation to the vagina.
Disclosure of Invention
The invention provides a traditional Chinese medicine composition for treating gynecological leucorrhea, which can effectively treat abnormal leucorrhea caused by pathogen infection and has small side effect.
The invention provides a traditional Chinese medicine composition for treating gynecological leucorrhea, which comprises the following components in parts by weight: 25-45 parts of phellodendron, 35-45 parts of fructus cnidii, 35-45 parts of bighead atractylodes rhizome, 70-80 parts of semen cuscutae, 20-35 parts of bunge corydalis herb, 15-25 parts of dragon bone, 40-50 parts of Chinese gall, 45-60 parts of raspberry, 75-90 parts of cherokee rose fruit and 10-20 parts of gordon euryale seed.
Preferably, the composition consists of the following components in parts by weight: 40 parts of phellodendron, 40 parts of common cnidium fruit, 40 parts of largehead atractylodes rhizome, 80 parts of south dodder seed, 30 parts of bunge corydalis herb, 20 parts of dragon bone, 50 parts of Chinese gall, 50 parts of raspberry, 80 parts of cherokee rose fruit and 20 parts of gordon euryale seed.
Preferably, the phellodendron bark and the white atractylodes rhizome are both roasted with salt.
The invention also provides a preparation method of the traditional Chinese medicine composition for treating gynecological leucorrhea, which specifically comprises the following steps:
Step 1, weighing 25-45 parts of phellodendron, 35-45 parts of fructus cnidii, 35-45 parts of bighead atractylodes rhizome, 70-80 parts of semen cuscutae, 20-35 parts of bunge corydalis herb, 15-25 parts of dragon bone, 40-50 parts of Chinese gall, 45-60 parts of raspberry, 75-90 parts of cherokee rose fruit and 10-20 parts of gordon euryale seed for later use;
Step 2, uniformly mixing the phellodendron, the fructus cnidii, the bighead atractylodes rhizome, the dodder, the bunge corydalis herb, the dragon bone, the gallnut, the raspberry, the cherokee rose fruit and the gordon euryale seed weighed in the step 1, adding water which is 8-12 times of the total weight of the mixture, decocting for 1.0-2.0h, filtering, and collecting first filtrate; adding water 6-8 times the total weight of the Chinese medicinal materials into the residue, decocting for 1.0-2.0 hr, filtering, collecting the second filtrate, mixing the first filtrate and the second filtrate, and concentrating to obtain soft extract.
the traditional Chinese medicine composition for treating gynecological leucorrhea provided by the invention can be prepared into pharmaceutically acceptable external preparations, including suppositories and lotions.
The effects of the raw materials of the invention are as follows:
Phellodendron bark: has the effects of clearing heat, eliminating dampness, purging fire, removing toxic substances, and removing bone-steaming. Can be used for treating leukorrhagia due to damp-heat, stranguria with astringency, dysentery due to damp-heat, jaundice, tinea pedis due to damp-heat, fistula, hectic fever due to yin deficiency, night sweat, spermatorrhea, pyocutaneous disease, toxic swelling, eczema, and pruritus.
Fructus cnidii: has the effects of warming kidney, strengthening yang, eliminating dampness, killing parasites, dispelling pathogenic wind and relieving itching. Can be used for treating male sexual impotence, scrotum wet itching, female infertility due to cold womb, leukorrhagia due to cold-dampness, pudendal pruritus, rheumatalgia, eczema, scabies, and tinea.
White atractylodes rhizome: invigorate spleen, replenish qi, dry dampness, induce diuresis, stop sweating, prevent abortion. Can be used for treating spleen deficiency, anorexia, abdominal distention, diarrhea, phlegm retention, dizziness, palpitation, edema, spontaneous perspiration, and threatened abortion. Tu Bai Zhu strengthens spleen, harmonizes stomach and prevents abortion. Can be used for treating spleen deficiency, anorexia, diarrhea, loose stool, and threatened abortion.
Dodder seed: has effects in nourishing liver and kidney, stopping nocturnal emission, arresting polyuria, preventing miscarriage, improving eyesight, and relieving diarrhea.
Corydalis Bungeana (L.) Merr: clearing away heat and toxic material. It can be used for treating febrile disease, hyperpyrexia, dysphoria, influenza, infectious hepatitis, nephritis, lymphoid tuberculosis, parotitis, furuncle, and other suppurative infections.
keel: has effects of relieving convulsion, tranquilizing mind, suppressing hyperactive liver, subsiding yang, astringing and inducing astringency. It can be used for treating unsteadiness of heart-mind, palpitation, insomnia, convulsive epilepsy, mania, vertigo, dizziness due to liver-yang, skin ulcer, prurigo, and unhealed ulcer.
Gallnut: has effects of astringing lung, lowering fire, relieving cough, arresting sweating, relieving diarrhea with astringents, arresting seminal emission, astringing, arresting hemorrhage, eliminating dampness, and healing sore. Can be used for treating cough, hemoptysis, spontaneous perspiration, night sweat, chronic diarrhea, chronic dysentery, spermatorrhea, metrorrhagia, hematochezia, hemorrhoid, eczema, and toxic swelling.
Raspberry: has effects of consolidating semen, reducing urination, benefiting liver and kidney, and improving eyesight. It can be used for treating spermatorrhea, enuresis, frequent micturition, deficiency of liver and kidney, and dim and unclear vision.
cherokee rose fruit: has the effects of securing essence, reducing urination, stopping leukorrhagia, astringing intestine and stopping diarrhea. It can be used for treating spermatorrhea, enuresis, frequent micturition, leukorrhagia, chronic diarrhea, dysentery, metrorrhagia, prolapse of anus, and uterine prolapse.
Gorgon fruit: has effects in invigorating kidney, stopping nocturnal emission, invigorating spleen, relieving diarrhea, eliminating dampness, and stopping leukorrhagia. It is used for treating spermatorrhea, spleen deficiency, chronic diarrhea, and leukorrhagia.
The traditional Chinese medicine composition for treating the gynecological leucorrhea provided by the invention takes the golden cypress and the bighead atractylodes rhizome as monarch drugs, and has the effects of detoxifying, drying dampness, strengthening spleen and replenishing qi; the dragon bone, the common cnidium fruit, the bunge corydalis herb, the Chinese gall and the cherokee rose fruit are taken as ministerial drugs to assist the effect of the monarch drugs in drying dampness and strengthening spleen, and the dragon bone, the Chinese gall and the cherokee rose fruit have the function of astringing and can play a role in stopping leukorrhagia; the dodder seed, the raspberry and the gordon euryale seed are taken as adjuvant drugs, so that the liver and the kidney are nourished, the kidney function is recovered to be normal, and abnormal leucorrhea caused by kidney insecurity is prevented. The whole formula is compatible, and the effects of detoxifying and drying dampness, strengthening spleen and replenishing qi, tonifying kidney and securing essence are achieved together.
Detailed Description
In order to make the technical solutions of the present invention better understood and enable those skilled in the art to practice the present invention, the following embodiments are further described, but the present invention is not limited to the following embodiments.
Example 1
a traditional Chinese medicine composition for treating gynecological leucorrhea comprises the following components: 25g of stir-fried golden cypress, 35g of common cnidium fruit, 35g of stir-fried bighead atractylodes rhizome, 70g of south dodder seed, 20g of bunge corydalis herb, 15g of dragon bone, 40g of Chinese gall, 45g of raspberry, 75g of cherokee rose fruit and 10g of gordon euryale seed.
the preparation method comprises the following steps:
Step 1, weighing 25g of stir-fried golden cypress, 35g of common cnidium fruit, 35g of stir-fried bighead atractylodes rhizome, 70g of south dodder seed, 20g of bunge corydalis herb, 15g of dragon bone, 40g of Chinese gall, 45g of raspberry, 75g of cherokee rose fruit and 10g of gordon euryale seed for later use;
Step 2, uniformly mixing the phellodendron, the fructus cnidii, the bighead atractylodes rhizome, the dodder, the bunge corydalis herb, the dragon bone, the gallnut, the raspberry, the cherokee rose fruit and the gordon euryale seed weighed in the step 1, adding water which is 8 times of the total weight of the mixture, decocting for 1.0 hour, filtering, and collecting primary filtrate; adding water 6 times the total weight of the above residue into the residue, decocting for 1.0 hr, filtering, collecting the second filtrate, mixing the first filtrate and the second filtrate, and concentrating to obtain soft extract.
Heating and melting appropriate matrix, adding the Chinese medicinal composition, mixing, injecting into a mold, molding, demolding, and cooling to obtain suppository type Chinese medicinal preparation for treating gynecological leucorrhea.
Example 2
A traditional Chinese medicine composition for treating gynecological leucorrhea comprises the following components: 45g of stir-fried golden cypress, 45g of common cnidium fruit, 45g of stir-fried bighead atractylodes rhizome, 80g of south dodder seed, 35g of bunge corydalis herb, 25g of dragon bone, 50g of Chinese gall, 60g of raspberry, 90g of cherokee rose fruit and 20g of gordon euryale seed.
The preparation method comprises the following steps:
Step 1, weighing 45g of stir-fried golden cypress, 45g of common cnidium fruit, 45g of stir-fried bighead atractylodes rhizome, 80g of south dodder seed, 35g of bunge corydalis herb, 25g of dragon bone, 50g of Chinese gall, 60g of raspberry, 90g of cherokee rose fruit and 20g of gordon euryale seed for later use;
Step 2, uniformly mixing the phellodendron, the fructus cnidii, the bighead atractylodes rhizome, the dodder, the bunge corydalis herb, the dragon bone, the gallnut, the raspberry, the cherokee rose fruit and the gordon euryale seed weighed in the step 1, adding water which is 12 times of the total weight of the mixture, decocting for 2.0h, filtering, and collecting primary filtrate; adding water in an amount which is 8 times of the total weight of the Chinese medicinal composition into the filter residue, decocting for 2.0h, filtering, collecting the second filtrate, mixing the first filtrate and the second filtrate, and concentrating to obtain a thick extract to obtain the Chinese medicinal composition.
Dissolving the above Chinese medicinal composition in water, adding appropriate adjuvant, filtering, and making into suspension to obtain lotion for treating gynecological leucorrhea.
Example 3
A traditional Chinese medicine composition for treating gynecological leucorrhea comprises the following components: 40g of stir-fried golden cypress, 40g of common cnidium fruit, 40g of stir-fried bighead atractylodes rhizome, 80g of south dodder seed, 30g of bunge corydalis herb, 20g of dragon bone, 50g of Chinese gall, 50g of raspberry, 80g of cherokee rose fruit and 20g of gordon euryale seed.
The preparation method comprises the following steps:
Step 1, weighing 40g of cortex phellodendri preparata, 40g of fructus cnidii, 40g of rhizoma atractylodis macrocephalae preparata, 80g of semen cuscutae, 30g of herba violae, 20g of keel, 50g of gallnut, 50g of raspberry, 80g of fructus rosae laevigatae and 20g of semen euryales for later use;
Step 2, uniformly mixing the phellodendron, the fructus cnidii, the bighead atractylodes rhizome, the dodder, the bunge corydalis herb, the dragon bone, the gallnut, the raspberry, the cherokee rose fruit and the gordon euryale seed weighed in the step 1, adding water which is 10 times of the total weight of the mixture, decocting for 1.5 hours, filtering, and collecting primary filtrate; adding water 7 times the total weight of the above residue into the residue, decocting for 1.5 hr, filtering, collecting the second filtrate, mixing the first filtrate and the second filtrate, and concentrating to obtain soft extract.
Heating and melting appropriate matrix, adding the Chinese medicinal composition, mixing, injecting into a mold, molding, demolding, and cooling to obtain suppository type Chinese medicinal preparation for treating gynecological leucorrhea.
Since the effect of the Chinese medicinal composition prepared in each example for treating abnormal leucorrhea is substantially the same, the product effect provided by the present invention will be described below only by using the Chinese medicinal composition prepared in example 3.
1 data and method
1.1 general data
80 patients with abnormal leucorrhea collected in 2016-2019 in 5 months are randomly selected. The patients were 18-49 years old, with the mean age being (35.8 ± 3.7) years.
1.2 methods
Randomly dividing 80 patients into control group and observation group, wherein each group comprises 40 patients, and the control group adopts gynecological gel once a day, one patient at a time; the observation group used the traditional Chinese medicine suppository obtained in example 3 once a day, one for each time. The sexual life is strictly prohibited in the treatment process of the patient, and the cervix is guaranteed not to be influenced by other factors. The control group and the observation group are continuously administered for 5 days, and the administration is stopped for 2 days, one treatment course is four weeks, and at least two treatment courses are administered. After stopping the drug, the patient is kept on follow-up observation for 6 months, and the relapse condition is recorded.
1.3 therapeutic efficacy criteria
The appearance of the cure of the patient: all clinical symptoms have disappeared;
Patient improvement performance: the clinical symptoms of the patients are improved;
Manifestation of ineffective patient treatment: the clinical symptoms of the patients have no obvious change, and the disease condition is not improved or even worsened.
calculating the effective rate: effective rate (cured number + good revolutions)/total number 100%
2 results
See table 1.
Table 1 clinical therapeutic effect results of the traditional Chinese medicine suppository prepared in example 3 on gynecological leucorrhea
| Grouping | Number of patients | Cure of disease | Improvement of life | Invalidation | Recurrence of disease | Effective rate (%) |
| Control group | 40 | 15 | 18 | 7 | 5 | 82.5 |
| observation group | 40 | 22 | 16 | 2 | 1 | 95.0 |
As can be seen from Table 1, the effective rate of the drugs used in the observation group for treating gynecological abnormal leucorrhea is significantly higher than that of the control group, and the traditional Chinese medicine suppository used in the observation group can effectively prevent the recurrence of gynecological abnormal leucorrhea. The traditional Chinese medicine preparation provided by the invention has a good treatment effect on gynecological abnormal leucorrhea and can effectively prevent relapse.
it should be noted that when the following claims refer to numerical ranges, it should be understood that both endpoints of each numerical range and any numerical value between the two endpoints can be selected, and since the steps and methods adopted are the same as those in embodiments 1 to 3, the present invention describes preferred embodiments in order to prevent redundant description, but once a person skilled in the art knows the basic inventive concept, other changes and modifications can be made to these embodiments. Therefore, it is intended that the appended claims be interpreted as including preferred embodiments and all such alterations and modifications as fall within the scope of the invention.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.
Claims (6)
1. The traditional Chinese medicine composition for treating gynecological leucorrhea is characterized by comprising the following components in parts by weight: 25-45 parts of phellodendron, 35-45 parts of fructus cnidii, 35-45 parts of bighead atractylodes rhizome, 70-80 parts of semen cuscutae, 20-35 parts of bunge corydalis herb, 15-25 parts of dragon bone, 40-50 parts of Chinese gall, 45-60 parts of raspberry, 75-90 parts of cherokee rose fruit and 10-20 parts of gordon euryale seed.
2. The traditional Chinese medicine composition for treating gynecological leucorrhea according to claim 1, characterized by comprising the following components in parts by weight: 40 parts of phellodendron, 40 parts of common cnidium fruit, 40 parts of largehead atractylodes rhizome, 80 parts of south dodder seed, 30 parts of bunge corydalis herb, 20 parts of dragon bone, 50 parts of Chinese gall, 50 parts of raspberry, 80 parts of cherokee rose fruit and 20 parts of gordon euryale seed.
3. The traditional Chinese medicine composition for treating gynecological leucorrhea according to claim 1 or 2, wherein said phellodendron bark and said white atractylodes rhizome are both stir-fried with salt.
4. The preparation method of the traditional Chinese medicine composition for treating gynecological leucorrhea according to claim 1, characterized by comprising the following steps:
Step 1, weighing 25-45 parts of phellodendron, 35-45 parts of fructus cnidii, 35-45 parts of bighead atractylodes rhizome, 70-80 parts of semen cuscutae, 20-35 parts of bunge corydalis herb, 15-25 parts of dragon bone, 40-50 parts of Chinese gall, 45-60 parts of raspberry, 75-90 parts of cherokee rose fruit and 10-20 parts of gordon euryale seed for later use;
step 2, uniformly mixing the phellodendron, the fructus cnidii, the bighead atractylodes rhizome, the dodder, the bunge corydalis herb, the dragon bone, the gallnut, the raspberry, the cherokee rose fruit and the gordon euryale seed weighed in the step 1, adding water which is 8-12 times of the total weight of the mixture, decocting for 1.0-2.0h, filtering, and collecting first filtrate; adding water 6-8 times the total weight of the Chinese medicinal materials into the residue, decocting for 1.0-2.0 hr, filtering, collecting the second filtrate, mixing the first filtrate and the second filtrate, and concentrating to obtain soft extract.
5. the preparation method of the traditional Chinese medicine composition for treating gynecological leucorrhea according to claim 4, wherein the traditional Chinese medicine composition can be prepared into a pharmaceutically acceptable external preparation.
6. The preparation method of the traditional Chinese medicine composition for treating gynecological leucorrhea according to claim 5, wherein the external preparation is suppository or lotion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910895757.4A CN110575481A (en) | 2019-09-21 | 2019-09-21 | traditional Chinese medicine composition for treating gynecological leucorrhea and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910895757.4A CN110575481A (en) | 2019-09-21 | 2019-09-21 | traditional Chinese medicine composition for treating gynecological leucorrhea and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110575481A true CN110575481A (en) | 2019-12-17 |
Family
ID=68813361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910895757.4A Pending CN110575481A (en) | 2019-09-21 | 2019-09-21 | traditional Chinese medicine composition for treating gynecological leucorrhea and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110575481A (en) |
-
2019
- 2019-09-21 CN CN201910895757.4A patent/CN110575481A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101904977A (en) | Medicament for treating mastitis and preparation method thereof | |
| CN101244241A (en) | Cunt shrinking and maintaining agent for gynaecologic treatment | |
| CN112843196A (en) | Female vagina tightening capsule and preparation process thereof | |
| CN104873851A (en) | Internal and external traditional-Chinese-medicine composition for treating bedsore | |
| CN102579807B (en) | Chinese medicine composition for treating dental ulcer | |
| CN104147559A (en) | Traditional Chinese medicine preparation for treating gynecological endometritis | |
| CN103933393A (en) | Traditional Chinese medicine for treating suppurative arthritis and preparation method thereof | |
| CN103007093A (en) | Medicine for treating gynecological inflammation and preparation method thereof | |
| CN105232880A (en) | Traditional Chinese medicine additive treating heat-toxin exuberance type hysteritis of sows and preparation method thereof | |
| CN104288417A (en) | Traditional Chinese medicine composition for treating dysmenorrhea and preparation method thereof | |
| CN102973744B (en) | Ointment for external use for mixed hemorrhoids care | |
| CN110575481A (en) | traditional Chinese medicine composition for treating gynecological leucorrhea and preparation method thereof | |
| CN106309903A (en) | Medicinal decoction for treating deafness and tinnitus and preparation method thereof | |
| CN102204977B (en) | Preparation method and application of ointment composition for external use for treating tubal nowhere | |
| CN111743982A (en) | Vulva lotion and preparation method thereof | |
| CN104997918A (en) | Foot tinea treating traditional Chinese medicine composition | |
| CN104189489A (en) | Medicament with effect of treating chronic eczema and preparation method thereof | |
| CN103720749A (en) | Traditional Chinese medicinal preparation for treating elytritis | |
| CN103494991B (en) | Traditional Chinese medicine preparation for treating female metrorrhagia and preparation method thereof | |
| CN102688453A (en) | Traditional Chinese medicine composite for treating breast cancer | |
| CN103893328A (en) | Traditional Chinese medicine pill used for treating hyperplasia of mammary glands | |
| CN102302763B (en) | Medicament for treating chronic laryngitis | |
| CN105106905A (en) | Traditional Chinese medicine prescription for treating headache | |
| CN105816601A (en) | Medicine composition for treating viral keratitis | |
| CN104107374A (en) | Traditional Chinese medicine capsule for treating cervical erosion and preparation method of traditional Chinese medicine capsule |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20191217 |
|
| RJ01 | Rejection of invention patent application after publication |