CN110545904A - 包含聚(噁唑啉)稳定剂的有机聚合物颗粒以及聚(噁唑啉)用于稳定有机聚合物颗粒的用途 - Google Patents

包含聚(噁唑啉)稳定剂的有机聚合物颗粒以及聚(噁唑啉)用于稳定有机聚合物颗粒的用途 Download PDF

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Publication number
CN110545904A
CN110545904A CN201880026806.4A CN201880026806A CN110545904A CN 110545904 A CN110545904 A CN 110545904A CN 201880026806 A CN201880026806 A CN 201880026806A CN 110545904 A CN110545904 A CN 110545904A
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CN
China
Prior art keywords
oxazoline
polymer particles
poly
organic polymer
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201880026806.4A
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English (en)
Chinese (zh)
Inventor
M·N·莱斯克
A·特拉格
U·S·舒伯特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Friedrich Schiller Universtaet Jena FSU
Original Assignee
Friedrich Schiller Universtaet Jena FSU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Friedrich Schiller Universtaet Jena FSU filed Critical Friedrich Schiller Universtaet Jena FSU
Publication of CN110545904A publication Critical patent/CN110545904A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L79/00—Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing nitrogen with or without oxygen or carbon only, not provided for in groups C08L61/00 - C08L77/00
    • C08L79/02—Polyamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0233—Polyamines derived from (poly)oxazolines, (poly)oxazines or having pendant acyl groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
    • C09D133/04—Homopolymers or copolymers of esters
    • C09D133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C09D133/062—Copolymers with monomers not covered by C09D133/06
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D167/00—Coating compositions based on polyesters obtained by reactions forming a carboxylic ester link in the main chain; Coating compositions based on derivatives of such polymers
    • C09D167/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
    • C09D7/40—Additives
    • C09D7/45—Anti-settling agents
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
    • C09D7/40—Additives
    • C09D7/65—Additives macromolecular
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C09K23/16—Amines or polyamines

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
CN201880026806.4A 2017-03-14 2018-03-12 包含聚(噁唑啉)稳定剂的有机聚合物颗粒以及聚(噁唑啉)用于稳定有机聚合物颗粒的用途 Pending CN110545904A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102017002454.5A DE102017002454A1 (de) 2017-03-14 2017-03-14 Organische Polymerpartikel enthaltend Poly(oxazolin)-Stabilisatoren und Verwendung von Poly(oxazolinen) zur Stabilisierung von organischen Polymerpartikeln
DE102017002454.5 2017-03-14
PCT/EP2018/000094 WO2018166651A1 (de) 2017-03-14 2018-03-12 Organische polymerpartikel enthaltend poly(oxazolin)-stabilisatoren und verwendung von poly(oxazolinen) zur stabilisierung von organischen polymerpartikeln

Publications (1)

Publication Number Publication Date
CN110545904A true CN110545904A (zh) 2019-12-06

Family

ID=61683735

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880026806.4A Pending CN110545904A (zh) 2017-03-14 2018-03-12 包含聚(噁唑啉)稳定剂的有机聚合物颗粒以及聚(噁唑啉)用于稳定有机聚合物颗粒的用途

Country Status (7)

Country Link
US (1) US11806355B2 (https=)
EP (1) EP3595804A1 (https=)
JP (1) JP7193470B2 (https=)
CN (1) CN110545904A (https=)
CA (1) CA3061034A1 (https=)
DE (1) DE102017002454A1 (https=)
WO (1) WO2018166651A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114940756A (zh) * 2022-06-02 2022-08-26 北京清科胜因生物科技有限公司 一种聚（2-噁唑啉）脂质与脂质纳米颗粒及应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11697746B2 (en) * 2013-03-15 2023-07-11 Conservation Technologies, Llc Protective water reversible clear coating for substrates

Citations (6)

* Cited by examiner, † Cited by third party
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EP0152551A1 (en) * 1983-11-15 1985-08-28 The Dow Chemical Company Miscible polymer blends containing poly(2-oxazoline)
EP0419793A1 (de) * 1989-09-26 1991-04-03 Hüls Aktiengesellschaft Polymere Costabilisatoren für Formmassen auf Basis von Polymerisaten des Vinylchlorids
CN101163725A (zh) * 2005-04-20 2008-04-16 株式会社日本触媒 反应性乳液及其生产方法
US20100041592A1 (en) * 2008-06-26 2010-02-18 Kabanov Alexander V Use of Amphiphilic Biocompatible Polymers for Solubilization of Hydrophobic Drugs
CN103429267A (zh) * 2011-01-09 2013-12-04 Anp科技公司 疏水分子诱导的支化聚合物集合体及其用途
US20140148523A1 (en) * 2012-11-28 2014-05-29 Mridula Nair Porous particles and methods of making them

Family Cites Families (12)

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JP2613384B2 (ja) * 1987-03-06 1997-05-28 コニカ株式会社 新規な界面活性剤を含有するハロゲン化銀写真感光材料
US5837768A (en) * 1994-12-08 1998-11-17 Hercules Incorporated Creping adhesives containing oxazoline polymers and methods of use thereof
JP4368183B2 (ja) 2003-11-06 2009-11-18 財団法人川村理化学研究所 ポリイオン会合体およびポリイオン会合体からなる生体物質キャリアー
US9028829B2 (en) 2004-02-20 2015-05-12 The Children's Hospital Of Philadelphia Uniform field magnetization and targeting of therapeutic formulations
JP2010511097A (ja) 2006-11-27 2010-04-08 マイクロアクティブ・コーポレイション 気体を徐放するための溶融加工可能な相溶性ポリマーブレンド
FR2975090B1 (fr) 2011-05-11 2017-12-15 Commissariat Energie Atomique Nanoparticules autodispersantes
CN102552146B (zh) 2012-02-13 2013-08-14 江西本草天工科技有限责任公司 表阿霉素脂质体及其制备和储存方法
WO2014172355A1 (en) * 2013-04-16 2014-10-23 Case Western Reserve University Neutrally-charged synthetic platelets to mitigate complement response
EP2842618A1 (en) 2013-09-02 2015-03-04 VITO NV (Vlaamse Instelling voor Technologisch Onderzoek NV) Apparatus and method for product recovery and electrical energy generation
CA2957764C (en) * 2014-08-13 2019-07-02 The Johns Hopkins University Glucocorticoid-loaded nanoparticles for prevention of corneal allograft rejection and neovascularization
WO2016061201A1 (en) * 2014-10-14 2016-04-21 The Brigham And Women's Hospital, Inc. Nanoparticles and methods of use
US10709645B2 (en) 2014-12-04 2020-07-14 Basf Se Microcapsules

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0152551A1 (en) * 1983-11-15 1985-08-28 The Dow Chemical Company Miscible polymer blends containing poly(2-oxazoline)
EP0419793A1 (de) * 1989-09-26 1991-04-03 Hüls Aktiengesellschaft Polymere Costabilisatoren für Formmassen auf Basis von Polymerisaten des Vinylchlorids
CN101163725A (zh) * 2005-04-20 2008-04-16 株式会社日本触媒 反应性乳液及其生产方法
US20100041592A1 (en) * 2008-06-26 2010-02-18 Kabanov Alexander V Use of Amphiphilic Biocompatible Polymers for Solubilization of Hydrophobic Drugs
CN103429267A (zh) * 2011-01-09 2013-12-04 Anp科技公司 疏水分子诱导的支化聚合物集合体及其用途
US20140148523A1 (en) * 2012-11-28 2014-05-29 Mridula Nair Porous particles and methods of making them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114940756A (zh) * 2022-06-02 2022-08-26 北京清科胜因生物科技有限公司 一种聚（2-噁唑啉）脂质与脂质纳米颗粒及应用
CN114940756B (zh) * 2022-06-02 2023-11-07 北京清科胜因生物科技有限公司 一种聚（2-噁唑啉）脂质与脂质纳米颗粒及应用

Also Published As

Publication number Publication date
JP2020512448A (ja) 2020-04-23
US20200122106A1 (en) 2020-04-23
CA3061034A1 (en) 2019-10-22
EP3595804A1 (de) 2020-01-22
US11806355B2 (en) 2023-11-07
WO2018166651A1 (de) 2018-09-20
DE102017002454A1 (de) 2018-09-20
JP7193470B2 (ja) 2022-12-20

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