CN110538075A - Method for decocting medicinal herbs by combining manual machine - Google Patents
Method for decocting medicinal herbs by combining manual machine Download PDFInfo
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Abstract
the application discloses a manual and mechanical combined decoction method, which comprises five steps of soaking, decocting, filtering and packaging, wherein the water consumption is calculated according to the water absorption rate, the combined evaporation capacity and the finished medicine amount of a single medicine, then a medicine soaking container with a corresponding size is selected according to the water addition amount, the medicine is placed in the medicine soaking container, and the medicine is soaked in pure cold water for 30 min. On the basis of scientific calculation and maintenance of the advantages of manual decoction and in combination with the mode of machine decoction and liquid medicine packaging, the advantages of the two are combined to establish a standard decoction flow; compared with the pure manual decoction, the tea is more convenient to store and drink; the invention can obtain the required dosage at one time through accurate calculation, control the water adding amount and without concentration, and has standard and fixed operation flow, thereby having high repeatability and further leading the effective components in the liquid medicine to be more stable.
Description
Technical Field
The application relates to the technical field of traditional Chinese medicine decoction, in particular to a manual and machine combined decoction method.
Background
With the returning of the visual field of the traditional Chinese medicine, the traditional Chinese medicine is favored by more and more people by the characteristics of treating roots and having small side effect, but compared with the convenience of direct oral administration of western medicines, the traditional Chinese medicine also needs to be decocted; the emerging machine decoction has the following defects:
(1) the special decocting method cannot be realized, the machine decocting is difficult to process the special decocting such as 'first decocting', 'later decocting', 'further decocting', 'adding', and the like, the animal A-piece type and ore type traditional Chinese medicines are hard in texture, and active ingredients are not easy to dissolve out, so the animal A-piece type and ore type traditional Chinese medicines need to be decocted for 30 minutes first, while the traditional Chinese medicines like mint, fructus amomi and the like which are easy to volatilize need to be put later, and the machine decocting is often 'one pot out', and the drug effect cannot reach the expected effect certainly;
(2) the traditional Chinese medicine cannot be decocted by open fire, the traditional Chinese medicine can be decocted as cooked rice, the taste can be better brought by the open fire, the requirements on duration of fire are also met, the traditional Chinese medicine is generally decocted quickly by the strong fire and then slowly by the small fire, the decocted decoction is mellow in medicine flavor and lasting in efficacy, and the traditional machine decocting cannot meet the requirements because the traditional machine decocting is electrically heated and decocted without the open fire;
(3) Effective component release is influenced by non-woven bag decoction, decoction pieces are required to be packed into the non-woven bag for decoction during machine decoction, stirring is not required, and the dissolution of the effective components is influenced by less medicine contact solution in the decoction process;
(4) The control of the water adding amount is difficult, and the liquid medicine with stable quality is difficult to obtain; in order to obtain a fixed amount of medicament, a large amount of water is required to be added in the decoction stage, and the concentration operation is performed after the decoction, so that the time and the labor are wasted, and a large amount of heat and water are wasted.
Disclosure of Invention
In order to solve the problems of manual decoction and machine decoction in the prior art, the invention provides a method for decocting medicines by combining a manual machine with a machine.
in order to achieve the aim, a manual machine combined decocting method is provided, and the specific scheme is as follows:
a manual and machine combined medicine decocting method comprises the following steps:
(1) soaking, counting the water absorption data of the single medicine, establishing a single medicine water absorption database, calculating the water addition amount of the whole prescription according to the water absorption rate of the single medicine and the combination of the evaporation amount and the finished medicine amount, selecting a medicine soaking container with a corresponding size according to the water addition amount, placing the medicine in the medicine soaking container, and soaking for 30min by pure cold water;
wherein, the establishment steps of the single-medicine water absorption database are as follows:
a1. Accurately weighing a certain amount of Chinese medicinal decoction pieces, and taking 5 samples of the same Chinese medicinal decoction piece;
a2. The water absorption rate and the water adding amount of the single-medicine decoction are as follows: adding a certain amount of water, soaking for 30 minutes, decocting according to the first decoction method corresponding to the Chinese medicinal decoction pieces, filtering, and draining water, and weighing the weight of the first decoction wet residue and the weight of the first decoction filtered decoction when no decoction is filtered; the single medicine is characterized in that the first decoction water absorption rate is (weight of first decoction wet dregs-weight of decoction pieces)/weight of decoction pieces is 100 percent, the first decoction water absorption rate is (weight of first decoction wet dregs-weight of decoction pieces), and the first decoction evaporation rate is (weight of first decoction test water addition, first decoction water absorption rate, first decoction filtered decoction weight);
Performing a2 operation on the five traditional Chinese medicine decoction piece samples to obtain the average values of the first decoction water absorption rate, the first decoction water absorption amount and the first decoction evaporation amount of the single medicine, and recording the average values into a single medicine water absorption database;
a3. the water absorption rate of the single medicament and the second decoction is as follows: adding a certain amount of water, decocting according to a second decoction method corresponding to the Chinese medicinal decoction pieces, filtering, and draining, when no medicinal liquid is filtered out, weighing the second decoction dregs and the weight of the second decoction filtered out medicinal liquid; the first decoction water absorption rate of the single medicine is (weight of the second decoction wet decoction dregs-weight of the first decoction wet decoction dregs)/weight of the decoction pieces is 100 percent, the second decoction water absorption rate is (weight of the second decoction wet decoction dregs-weight of the first decoction wet decoction dregs), and the second decoction evaporation rate is (weight of the second decoction test water addition rate-the second decoction water absorption rate-the weight of the second decoction filtered decoction;
Performing a3 operation on the five Chinese medicinal decoction piece samples to obtain the average values of the two-decoction water absorption rate, the two-decoction water absorption amount and the two-decoction evaporation amount of the single medicament, and recording the average values into a single medicament water absorption database;
the data of the water absorption database of the single medicine is adopted for calculation, and the calculation formula of the water adding amount of the first-decocted single medicine is as follows: adding water into the first-decocted single medicine, namely the water absorption of the first-decocted medicine, the evaporation capacity of the first-decocted medicine and the required medicine decoction amount;
The water absorption database data of the single medicine is adopted for calculation, and the water adding amount calculation formula of the two-decoction single medicine is as follows: adding water into the two-decoction single medicine, namely the water absorption amount of the two-decoction, the evaporation amount of the two-decoction and the required medicine decoction amount;
Calculating by adopting the data of the single-medicine water absorption database, wherein the total prescription first-decocting water addition amount is the sum of the first-decocting water absorption amount of all single medicines in the prescription, the first-decocting evaporation amount and the required decoction amount;
calculating by adopting the data of the single-medicine water absorption database, wherein the water adding amount of the second decoction of the whole prescription is equal to the sum of the two water absorption amounts of all the single medicines of the prescription, the two evaporation amounts and the required decoction amount;
(2) Decocting, namely selecting a decocting pot with a corresponding volume according to the number of the decocted medicaments, determining the decocting times, time and duration according to the properties of the medicaments and the advice of doctors, and stirring for 2-3 times in the decocting process;
(3) Filtering, namely filtering the decoction dregs for 2-5 times by using a medicine sieve;
(4) And (3) packaging, pouring the decocted and filtered liquid medicine into the thoroughly cleaned machine decocting machine according to the flow of the machine decocting machine, then preheating the machine, adjusting the dosage of each package on a packaging machine according to the conventional or medical advice, opening a sub-packaging button for sub-packaging and filling, pouring the leaked packages into the packages again for packaging, determining that the labels on the packaged outer packages are consistent with the medicine picking list, and marking the packaged first bag and the packaged last bag of medicine.
preferably, in the step (2), the decocting comprises twice of first decocting and second decocting, wherein the first decocting is 15-20 minutes after the exterior-releasing medicines, the heat-clearing medicines and the aromatic medicines are boiled, and the second decocting is 10-15 minutes; boiling the nourishing medicine with strong fire, and then slowly decocting with slow fire, wherein the first decoction is decocted for 30-35 minutes, and the second decoction is decocted for 25-30 minutes; the rest medicines are boiled and decocted for 30 minutes in the first decoction, and 20 minutes in the second decoction.
Preferably, in the step (2), after the medicine is boiled, the medicine is stirred for 2 times, and each stirring time is 2-5 min.
Preferably, in the step (2), the first decocted herbs are prepared for the prescription, and the first decocted herbs are soaked and boiled for 30 minutes and then decocted with other herbs.
preferably, in the step (2), the medicines are added after the preparation of the medicines, and the medicines are added for decocting for 5-10 minutes when the other medicines are about to be decocted for a predetermined time.
preferably, in step (2), the melted and melted medicines are prepared, and after the other medicines are decocted to a predetermined amount and removed from the decoction, the decoction is placed into the decoction for slow fire decoction, stirring and dissolution.
preferably, in the step (2), the prescription is injected with another decocted medicine, the decoction is carried out for about 30 minutes in a decocting pot, the decoction is uniformly mixed with the decoction obtained by decocting other medicines in the prescription and then packaged, and the time for decocting and stewing and the proper amount of water can be specifically determined according to the characteristics of the medicine properties.
Preferably, in the step (2), the prescription is filled with the medicine to be decocted, and is filled into a bag for decocting, and then is decocted with other medicines after the bag is closed.
preferably, in the step (2), the prescription is injected with the medicine for blending and taking with water, and the blended and taken with water is added with a proper amount of decocted medicine juice or boiled water for taking with water.
Preferably, in the step (4), the size of the medicine sieve is 100 meshes.
The invention has the beneficial effects that:
1. The invention controls the water adding amount through accurate calculation, does not need concentration, can obtain the required medicament amount at one time, saves time and labor, and saves energy and water; the standard and fixed operation flow ensures high repeatability, and further, the effective components in the liquid medicine are more stable;
2. Compared with decoction by a machine, the decoction method provided by the invention has the advantages that the prepared liquid medicine is darker in color, thicker in decoction and thicker in medicinal flavor; the variable weight of the different chemical components between the two groups is measured according to various indexes, the result shows that the decocting method provided by the invention is obviously separated from the machine decocting group, and the content of the chemical components in the decocting method provided by the invention is identified to be obviously higher than that in the machine decoction under the positive and negative ion modes, which shows that the decocting method and the machine decocting mode provided by the invention can generate certain influence on the drug effect components of the decoction, and the main reason is that: firstly, when the decoction method provided by the invention is used for decocting the medicines, a non-woven bag is not required to be arranged, the effective stirring can be realized in the decoction process, the solution is fully contacted with decoction pieces, and the effective components are easier to dissolve; when the machine is used for decocting the medicines, the decoction pieces are required to be arranged in a non-woven bag for wrapping and decocting, the stirring cannot be carried out, the medicine contact solution is less in the decocting process, and the dissolution of effective components is influenced; the machine decocting is sealed and decocted for 1 time, the decocting method provided by the invention needs to decoct for 2 times, and new solvent is replaced for 2 times, which is beneficial to reestablishing concentration difference and promoting the dissolution of effective components, and the decocting times are important factors influencing the release of the medicinal components;
3. compared with the pure manual decoction, the decoction method provided by the invention has the advantages that the storage time is long, and the storage is convenient;
4. the invention establishes a standard decoction flow, can ensure the drug effect of the traditional Chinese medicine to the maximum extent and is convenient for patients to take.
Detailed Description
In order to make the technical solutions in the embodiments of the present application better understood, the technical solutions in the embodiments of the present application will be clearly and completely described below, and it is obvious that the described embodiments are only some embodiments of the present application, not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
The operation flow of the pharmacy on the aspect of decoction treatment is as follows:
first, the receiver audits
filling and printing decoction replacing labels by Chinese medicine professionals: the contents include names, decoction methods, special decoction methods and the like. The medicine is handed over to the operator for decocting the medicine along with the medicine, so as to avoid the poor circulation and the leakage.
Second, soaking
1. Checking the filling decoction records: the Chinese medicine is taken from the storage place of the Chinese medicine to be decocted, and when the Chinese medicine is taken, the medicine taking list and the decoction label must be checked, and the name, the dosage and the special decocting method of the patient must be checked. And (5) after checking, performing subsequent operation and filling the decoction record.
2. labeling a container: the medicine decocting container is distributed and attached to the container for soaking the medicine along with the medicine grabbing list and the decocting label, so that error accidents are avoided.
3. Calculating the water adding amount: according to the water absorption of single medicine, the water absorption and water addition of the whole prescription decoction pieces are calculated, the water absorption of 300 single medicine decoction pieces is counted at present, a water absorption database of the single medicine decoction pieces is established, and the total water addition of the prescription, namely the optimal water consumption for decocting the medicines, is calculated by using system software in combination with the evaporation capacity and the finished medicine quantity.
the calculation method comprises the following steps:
The single-medicine water absorption database is established by the following steps:
a1. accurately weighing a certain amount of Chinese medicinal decoction pieces, and taking 5 samples of the same Chinese medicinal decoction piece;
a2. The water absorption rate and the water adding amount of the single-medicine decoction are as follows: adding a certain amount of water, soaking for 30 minutes, decocting according to the first decoction method corresponding to the Chinese medicinal decoction pieces, filtering, and draining water, and weighing the weight of the first decoction wet residue and the weight of the first decoction filtered decoction when no decoction is filtered; the single medicine is characterized in that the first decoction water absorption rate is (weight of first decoction wet dregs-weight of decoction pieces)/weight of decoction pieces is 100 percent, the first decoction water absorption rate is (weight of first decoction wet dregs-weight of decoction pieces), and the first decoction evaporation rate is (weight of first decoction test water addition, first decoction water absorption rate, first decoction filtered decoction weight);
performing a2 operation on the five traditional Chinese medicine decoction piece samples to obtain the average values of the first decoction water absorption rate, the first decoction water absorption amount and the first decoction evaporation amount of the single medicine, and recording the average values into a single medicine water absorption database;
a3. The water absorption rate of the single medicament and the second decoction is as follows: adding a certain amount of water, decocting according to a second decoction method corresponding to the Chinese medicinal decoction pieces, filtering, and draining, when no medicinal liquid is filtered out, weighing the second decoction dregs and the weight of the second decoction filtered out medicinal liquid; the first decoction water absorption rate of the single medicine is (weight of the second decoction wet decoction dregs-weight of the first decoction wet decoction dregs)/weight of the decoction pieces is 100 percent, the second decoction water absorption rate is (weight of the second decoction wet decoction dregs-weight of the first decoction wet decoction dregs), and the second decoction evaporation rate is (weight of the second decoction test water addition rate-the second decoction water absorption rate-the weight of the second decoction filtered decoction;
Performing a3 operation on the five Chinese medicinal decoction piece samples to obtain the average values of the two-decoction water absorption rate, the two-decoction water absorption amount and the two-decoction evaporation amount of the single medicament, and recording the average values into a single medicament water absorption database;
The data of the water absorption database of the single medicine is adopted for calculation, and the calculation formula of the water adding amount of the first-decocted single medicine is as follows: adding water into the first-decocted single medicine, namely the water absorption of the first-decocted medicine, the evaporation capacity of the first-decocted medicine and the required medicine decoction amount;
The water absorption database data of the single medicine is adopted for calculation, and the water adding amount calculation formula of the two-decoction single medicine is as follows: adding water into the two-decoction single medicine, namely the water absorption amount of the two-decoction, the evaporation amount of the two-decoction and the required medicine decoction amount;
Calculating by adopting the data of the single-medicine water absorption database, wherein the total prescription first-decocting water addition amount is the sum of the first-decocting water absorption amount of all single medicines in the prescription, the first-decocting evaporation amount and the required decoction amount;
The data of the single medicine water absorption database is adopted for calculation, and the water adding amount of the whole prescription II is equal to the sum of the two water absorption amounts of all the single medicines in the prescription, the two evaporation amounts and the required decoction amount.
4. Soaking time: placing the materials to be decocted in a clean stainless steel barrel, and soaking in pure cold water for 30 min.
Thirdly, decocting by hand
1. selecting a medicine decocting pot: the medicine decocting pot with proper volume is selected according to the number of the medicines to be decocted, the general number of the medicines is 7, and related documents are placed at a designated position near the medicine decocting pot.
2. determining the decoction time: the decoction time is determined according to the advice of the doctor. If no physician order is given, the herbs should be decocted for 30 minutes and 20 minutes after boiling. The exterior-releasing, heat-clearing and aromatic herbs should not be decocted for a long time, and after boiling, the first decoction is decocted for 15-20 minutes, and the second decoction is decocted for 10-15 minutes. The nourishing medicine is boiled by strong fire firstly, then is decocted by slow fire, the first decoction is decocted for 30-35 minutes, and the second decoction is decocted for 25-30 minutes.
3. determining the decocting times: the number of times of decoction is determined according to the advice of the doctor, and is 1 to 3 times. Decocting for 2 times without advice.
4. Stirring: stirring for 2-3 times in the decocting process. Especially, the medicine is stirred for a long time after being boiled.
5. The special decocting method comprises the following steps: all herbs that are indicated to have special requirements such as first decocted, then decocted, mixed and melted should be treated according to the physician's advice to ensure the quality of the decocted herbs.
(1) decocting the medicinal materials firstly: generally, the decoction is boiled for 30 minutes, then decocted with other herbs and soaked in the decoction.
(2) The following medicines are added: the first decoction is added for decocting for 5-10 minutes when the first decoction is about to be decocted for a predetermined time.
(3) Melting and melting the materials: decocting the other materials to a predetermined amount, removing residues, decocting with slow fire, stirring, and dissolving.
(4) decocting the other medicines: decocting for about 30 minutes in a decocting pan, mixing the decoction with decoction obtained by decocting other materials in the formula, and packaging. The time for decocting and stewing the special medicines can be determined according to the characteristics of the medicine properties, and a proper amount of water can be used.
(5) decocting the medicines in bags: it should be decocted with other herbs after being packed and decocted in a closed bag. The material of the bag for decoction should meet the requirement of medicinal use, and the bag is harmless to human body and has filtration function.
(6) mixing and taking the medicines after being infused with water: the medicine is taken after being mixed with water or mixed with proper amount of decocted medicine liquid or boiled water without decoction.
(7) there are other drugs that require special decocting: the operation is carried out according to the prescription requirement.
6. concentration:
(1) The requirement for children to take medicine is small and thick, so that the medicine can be conveniently taken, therefore, after the first decoction and the second decoction for pediatrics are combined, heating and concentrating are needed to be performed to a proper amount.
(2) the total water absorption and water addition amount of the prescription of the dosage of adults are calculated by a computer system, concentration is not needed, however, as some grass leaf medicines have high water absorption, in order to ensure that the medicines can fully roll during decoction, more water is added, and the medicines are properly concentrated according to the dosage requirement after decoction.
7. And (3) filtering: for better taste, the herb residue is filtered by a 100-mesh sieve for several times.
Four, machine packaging
1. preheating a machine: the method comprises the steps of packaging liquid medicine by using a machine decocting machine, pouring the liquid medicine decocted by hand into the machine decocting machine which is thoroughly cleaned according to the flow of the machine decocting machine, and then preheating the machine.
2. Subpackaging and filling: adjusting the dosage of each package on a packaging machine according to the conventional or medical advice, opening a split charging button, and subpackaging.
3. Checking the quality of a finished product: if leakage package exists, pouring again and packaging, labeling the packaged outer bag, checking whether the label is consistent with the prescription list, delivering to a medicine receiving and sending place, and placing a decoction storage area.
4. Marking the first and last bags of medicine: the first and last bags are marked to remind the patient to take the two bags first.
Cleaning container
Thoroughly removing the dregs, scrubbing, washing, boiling and scrubbing again. So as to ensure that the medicine soaking barrel, the medicine decocting pot and the packaging machine are cleaned to be clean and wait for the next use.
1. Treating medicine dregs: taking out the decoction dregs bag in the decoction pot, and placing the decoction dregs bag in a specified area.
2. Cleaning a medicine soaking barrel: cleaning with water until the product is clean, and waiting for next use.
3. Cleaning the frying pan: cleaning with water until the product is clean, and waiting for next use.
4. cleaning a packaging machine: cleaning a liquid storage barrel and a nozzle of the packaging machine, cleaning a liquid medicine conveying pipeline, operating according to the cleaning rules of a medicine decocting machine in a medicine decocting chamber, and waiting for the next use.
Sixthly, dispensing medicine
when the patient receives the decoction, the name and the signature of the patient are checked; if the soup is express, the phone checks the name, address and number of the express bill.
to further compare the method of decocting the medicine of the present invention with machine decocting, an example, 2 comparative examples are provided below to illustrate the present application in detail.
Example 1
Combining a manual machine with decoction: putting 75g of 1 dose of prescription decoction pieces into a clean stainless steel pot, wherein the required amount of 1 dose of prescription decoction pieces is 400ml, calculating according to software, adding 390g of water into the first decoction, soaking for 30min, heating with strong fire to boil, keeping the slightly boiling state with slow fire for 30min, filtering while hot, and collecting the filtrate. According to the software calculation, the water adding amount of the second decoction is 310g, the second decoction is heated by strong fire until boiling, then the second decoction is kept in a slightly boiling state by slow fire for 20min, the second decoction is filtered while hot, water is drained, the filtrate is collected, the filtrate for 2 times is combined, the volume is 402ml, one half of the filtrate is refrigerated in an open mode, and the other half of the filtrate is packaged into bags through a machine according to the requirements and is refrigerated. According to the above operation, 3 doses of the prescription are 1 sample, 10 batches of samples are prepared in total, the dose obtained by each prescription in 10 batches of samples is in the range of 397-404 ml, and the concentration operation is not needed.
comparative example 1
75g of 1 dose of prescription decoction pieces are uniformly mixed and then put into a non-woven fabric bag to be placed in a decocting machine. Adding water 10 times of the total amount of the decoction pieces, soaking in a non-woven bag for 30 min. The decocting process comprises heating with strong fire for 30min, heating with slow fire for 20min, filtering, concentrating in water bath to 400mL, and packaging. According to the above procedure, 3 doses were prescribed for 1 specimen, and 10 batches of samples were prepared in total.
Comparative example 2
Combining a manual machine with decoction: putting 75g of 1 dose of prescription decoction pieces into a clean stainless steel pot, wherein the required amount of 1 dose of prescription decoction piece is 500ml, soaking the decoction pieces for 30min with water which is 3cm above the surface of the decoction pieces according to the conventional operation, heating with strong fire until the decoction pieces are boiled, keeping the slightly boiling state for 30min with slow fire, filtering while the decoction pieces are hot, and collecting the filtrate. According to the calculation of software, the water adding amount of the second decoction is calculated according to the conventional operation, the second decoction is submerged 2cm above the surface of the decoction pieces, the second decoction is heated to boil by strong fire, then the second decoction is kept in a slightly boiling state for 20min by slow fire, the second decoction is filtered while the decoction pieces are hot, the water is drained, the filtrate is collected, the 2 times of filtrate with the volume of 576ml is combined, the second filtrate is concentrated to 400ml, one half of the second filtrate is refrigerated in an open mode, and the. According to the above procedure, 3 doses of the prescription were 1 specimen, 10 samples were prepared, and the dose obtained from each prescription in 10 samples was concentrated to 400 ml.
A. Example 1 and comparative example 1 will be compared
from the appearance of the decoction, compared with the decoction of comparative example 1, the decoction of example 1 has darker color, thicker decoction and stronger medicinal taste.
From the storage of the decoction, the taste of the decoction in the open refrigeration of the comparative example 1 is unchanged after 2 days of refrigeration, but the bacterial colony of the decoction is increased by 20 percent, and the taste of the decoction in the open refrigeration is deteriorated after 3 days of refrigeration; the bacterial colonies of the liquid medicines in the sealed and bag-shaped refrigeration of the example 1 and the sealed and bag-shaped refrigeration of the comparative example 1 are not obviously increased after being stored for 10 days, the bacterial colonies of the liquid medicines are increased by 20 percent after being stored for 17 days, and the taste of the liquid medicines is slightly deteriorated after being stored for 25 days, namely, the storage time of the liquid medicines in the sealed and bag-shaped refrigeration of the example 1 and the sealed and bag-shaped refrigeration of the comparative example 1 is basically consistent.
From the aspect of components, a proper amount of decoction of the example 1 and the decoction of the comparative example 1 are taken, the decoction is filtered by a 0.22 mu m microporous membrane, 10 mu L of filtrate is taken for sample injection analysis, the sample is purified by a chromatographic column and subjected to mass spectrometry, and mass spectrometry data are analyzed by Progenetics QI software, so that the obtained data show that the significant difference exists between the example 1 and the comparative example 1, and the existence of different chemical components has great influence on the 2 decoction modes. 40 chemical components are identified, and the content of the chemical components in the decoction method provided by the invention is obviously higher than that in machine decoction.
B. Example 1 and comparative example 2 will be compared
From the appearance of the decoction, compared with the decoction of the comparative example 1, the appearance of the decoction of the example 1 is not obviously different;
From the storage of the decoction, the taste of the decoction in comparative example 2 is not changed after the cold storage for 2 days, but the bacterial colony of the decoction is increased by 20 percent, and the taste of the decoction in the cold storage is deteriorated after the cold storage for 3 days; the bacterial colony of the liquid medicine is not obviously increased after the liquid medicine is stored for 10 days in the sealed and bagged refrigeration mode in the comparative example 2, the bacterial colony of the liquid medicine is increased by 20 percent after the liquid medicine is stored for 17 days, and the taste of the liquid medicine is slightly deteriorated after the liquid medicine is stored for 25 days, namely the liquid medicine is stored for approximately consistent time in the sealed and bagged refrigeration mode in the example 1 and the sealed and bagged refrigeration mode in the comparative example;
From the aspect of components, a proper amount of the decoction of the example 1 and the decoction of the comparative example 2 are taken, filtered by a 0.22 mu m microporous membrane, 10 mu L of the filtrate is taken for sample injection analysis, purified by a chromatographic column and subjected to mass spectrometry, and mass spectrometry data are analyzed by Progenetics QI software, so that the obtained data show that a certain difference exists between the example 1 and the comparative example 2, and the existence of different chemical components has great influence on the 2 water adding modes. 40 chemical components are identified, the content of the chemical components in the example 1 is higher than that in the comparative example 2 in whole, the content of each main chemical component in 10 samples of the example 1 is within 1 percent, and the content of each main chemical component in 10 samples of the comparative example 2 is 3-5 percent.
the above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims (10)
1. A manual and machine combined medicine decocting method is characterized by comprising the following steps:
(1) Soaking, counting the water absorption data of the single medicine, establishing a single medicine water absorption database, calculating the water addition amount of the whole prescription according to the water absorption rate of the single medicine and the combination of the evaporation amount and the finished medicine amount, selecting a medicine soaking container with a corresponding size according to the water addition amount, placing the medicine in the medicine soaking container, and soaking for 30min by pure cold water;
wherein, the establishment steps of the single-medicine water absorption database are as follows:
a1. Accurately weighing a certain amount of Chinese medicinal decoction pieces, and taking 5 samples of the same Chinese medicinal decoction piece;
a2. The water absorption rate and the water adding amount of the single-medicine decoction are as follows: adding a certain amount of water, soaking for 30 minutes, decocting according to the first decoction method corresponding to the Chinese medicinal decoction pieces, filtering, and draining water, and weighing the weight of the first decoction wet residue and the weight of the first decoction filtered decoction when no decoction is filtered; the single medicine is characterized in that the first decoction water absorption rate is (weight of first decoction wet dregs-weight of decoction pieces)/weight of decoction pieces is 100 percent, the first decoction water absorption rate is (weight of first decoction wet dregs-weight of decoction pieces), and the first decoction evaporation rate is (weight of first decoction test water addition, first decoction water absorption rate, first decoction filtered decoction weight);
performing a2 operation on the five traditional Chinese medicine decoction piece samples to obtain the average values of the first decoction water absorption rate, the first decoction water absorption amount and the first decoction evaporation amount of the single medicine, and recording the average values into a single medicine water absorption database;
a3. The water absorption rate of the single medicament and the second decoction is as follows: adding a certain amount of water, decocting according to a second decoction method corresponding to the Chinese medicinal decoction pieces, filtering, and draining, when no medicinal liquid is filtered out, weighing the second decoction dregs and the weight of the second decoction filtered out medicinal liquid; the first decoction water absorption rate of the single medicine is (weight of the second decoction wet decoction dregs-weight of the first decoction wet decoction dregs)/weight of the decoction pieces is 100 percent, the second decoction water absorption rate is (weight of the second decoction wet decoction dregs-weight of the first decoction wet decoction dregs), and the second decoction evaporation rate is (weight of the second decoction test water addition rate-the second decoction water absorption rate-the weight of the second decoction filtered decoction;
Performing a3 operation on the five Chinese medicinal decoction piece samples to obtain the average values of the two-decoction water absorption rate, the two-decoction water absorption amount and the two-decoction evaporation amount of the single medicament, and recording the average values into a single medicament water absorption database;
The data of the water absorption database of the single medicine is adopted for calculation, and the calculation formula of the water adding amount of the first-decocted single medicine is as follows: adding water into the first-decocted single medicine, namely the water absorption of the first-decocted medicine, the evaporation capacity of the first-decocted medicine and the required medicine decoction amount;
the water absorption database data of the single medicine is adopted for calculation, and the water adding amount calculation formula of the two-decoction single medicine is as follows: adding water into the two-decoction single medicine, namely the water absorption amount of the two-decoction, the evaporation amount of the two-decoction and the required medicine decoction amount;
calculating by adopting the data of the single-medicine water absorption database, wherein the total prescription first-decocting water addition amount is the sum of the first-decocting water absorption amount of all single medicines in the prescription, the first-decocting evaporation amount and the required decoction amount;
Calculating by adopting the data of the single-medicine water absorption database, wherein the water adding amount of the second decoction of the whole prescription is equal to the sum of the two water absorption amounts of all the single medicines of the prescription, the two evaporation amounts and the required decoction amount;
(2) decocting, namely selecting a decocting pot with a corresponding volume according to the number of the decocted medicaments, determining the decocting times, time and duration according to the properties of the medicaments and the advice of doctors, and stirring for 2-3 times in the decocting process;
(3) Filtering, namely filtering the decoction dregs for 2-5 times by using a medicine sieve;
(4) and (3) packaging, pouring the decocted and filtered liquid medicine into the thoroughly cleaned machine decocting machine according to the flow of the machine decocting machine, then preheating the machine, adjusting the dosage of each package on a packaging machine according to the conventional or medical advice, opening a sub-packaging button for sub-packaging and filling, pouring the leaked packages into the packages again for packaging, determining that the labels on the packaged outer packages are consistent with the medicine picking list, and marking the packaged first bag and the packaged last bag of medicine.
2. the method for decocting medicinal herbs according to claim 1, wherein in the step (2), the decoction comprises two times of first decoction and second decoction, wherein the first decoction is 15 to 20 minutes and the second decoction is 10 to 15 minutes after the exterior-releasing herbs, the heat-clearing herbs and the aromatic herbs are boiled; boiling the nourishing medicine with strong fire, and then slowly decocting with slow fire, wherein the first decoction is decocted for 30-35 minutes, and the second decoction is decocted for 25-30 minutes; the rest medicines are boiled and decocted for 30 minutes in the first decoction, and 20 minutes in the second decoction.
3. The decoction method according to claim 1, wherein in the step (2), the mixture is stirred for 2 times, each time for 2-5 min after the mixture is boiled.
4. The method for decocting medicinal herbs of claim 1, wherein in the step (2), the first decocted herbs are prepared, and the decoction is first soaked and boiled for 30 minutes and then decocted with other herbs.
5. The method of claim 1, wherein in step (2), the other drugs are decocted for 5-10 minutes when the other drugs are to be decocted for a predetermined time.
6. The method according to claim 1, wherein in the step (2), the melted and melted herbs are injected, and after the other herbs are decocted to a predetermined amount and removed from the decoction, the mixture is decocted with slow fire, stirred and dissolved.
7. The method for decocting medicinal herbs according to claim 1, wherein in the step (2), the prescription is filled with another medicine to be decocted, the decoction is decocted for about 30 minutes in a decocting pot, the decoction is uniformly mixed with the decoction obtained by decocting other medicines in the prescription and then packaged, and the time for decocting and stewing and the proper amount of water can be determined according to the characteristics of the medicine properties.
8. The decocting method of claim 1, wherein in step (2), the prescription is filled with the decoction-wrapped herbs, and the decoction-wrapped herbs are closed and decocted with other herbs.
9. the method for decocting medicinal herbs according to claim 1, wherein in the step (2), the prescription is prepared by adding the medicines for blending and taking with water, and the blended and taken with water is added with proper amount of decocted decoction or boiled water for taking with water.
10. the decoction method according to claim 1, wherein in the step (4), the size of the medicine sieve is 100 meshes.
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Application publication date: 20191206 |