CN110522668A - A kind of micro-current antibacterial facial mask and preparation method thereof - Google Patents
A kind of micro-current antibacterial facial mask and preparation method thereof Download PDFInfo
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- CN110522668A CN110522668A CN201910747882.0A CN201910747882A CN110522668A CN 110522668 A CN110522668 A CN 110522668A CN 201910747882 A CN201910747882 A CN 201910747882A CN 110522668 A CN110522668 A CN 110522668A
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- 230000000844 anti-bacterial Effects 0.000 title claims abstract description 32
- 238000002360 preparation method Methods 0.000 title claims description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 39
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000004909 Moisturizer Substances 0.000 claims abstract description 13
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 13
- 230000001333 moisturizer Effects 0.000 claims abstract description 13
- 239000008213 purified water Substances 0.000 claims abstract description 13
- 239000002562 thickening agent Substances 0.000 claims abstract description 13
- 206010018987 Haemorrhage Diseases 0.000 claims abstract description 12
- 230000000740 bleeding Effects 0.000 claims abstract description 12
- 231100000319 bleeding Toxicity 0.000 claims abstract description 12
- 230000000694 effects Effects 0.000 claims abstract description 11
- 238000007689 inspection Methods 0.000 claims abstract description 5
- 230000001954 sterilising Effects 0.000 claims abstract description 5
- 238000003756 stirring Methods 0.000 claims abstract description 5
- 239000000758 substrate Substances 0.000 claims description 40
- 229920002674 hyaluronan Polymers 0.000 claims description 19
- 229960003160 hyaluronic acid Drugs 0.000 claims description 19
- MAKUBRYLFHZREJ-JWBQXVCJSA-M sodium;(2S,3S,4R,5R,6R)-3-[(2S,3R,5S,6R)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylate Chemical compound [Na+].CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C([O-])=O)O[C@@H](O)[C@H](O)[C@H]1O MAKUBRYLFHZREJ-JWBQXVCJSA-M 0.000 claims description 19
- 229910052709 silver Inorganic materials 0.000 claims description 10
- 239000004332 silver Substances 0.000 claims description 10
- 229920000642 polymer Polymers 0.000 claims description 8
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Tris Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 6
- 229960001631 Carbomer Drugs 0.000 claims description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 229920001888 polyacrylic acid Polymers 0.000 claims description 5
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical group CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 4
- 150000001875 compounds Chemical group 0.000 claims description 4
- 239000004744 fabric Substances 0.000 claims description 4
- 238000000265 homogenisation Methods 0.000 claims description 4
- 239000000463 material Substances 0.000 claims description 4
- 238000004806 packaging method and process Methods 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- ZZVUWRFHKOJYTH-UHFFFAOYSA-N Diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 claims 1
- 230000005611 electricity Effects 0.000 claims 1
- 230000032258 transport Effects 0.000 claims 1
- 230000002335 preservative Effects 0.000 abstract description 10
- 239000003755 preservative agent Substances 0.000 abstract description 10
- 230000001225 therapeutic Effects 0.000 abstract description 8
- 230000003020 moisturizing Effects 0.000 abstract description 5
- 230000029663 wound healing Effects 0.000 abstract description 5
- 239000004745 nonwoven fabric Substances 0.000 abstract description 4
- 231100000241 scar Toxicity 0.000 abstract description 4
- 239000003242 anti bacterial agent Substances 0.000 abstract description 3
- 230000002421 anti-septic Effects 0.000 abstract description 3
- 230000001580 bacterial Effects 0.000 abstract description 3
- 239000000969 carrier Substances 0.000 abstract description 3
- 210000003491 Skin Anatomy 0.000 description 24
- 238000011112 process operation Methods 0.000 description 12
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0606—Face
Abstract
The present invention provides a kind of micro-current antibacterial facial masks, including following components: thickener, moisturizer, bleeding agent, glycerol, tridecanoic peptide, neutralizer, and purified water, the carrier for carrying the above component is non-woven fabrics, addition stirring in order in a reservoir, sterilizing, bag is packed into after quality inspection is qualified, the functional components for solving existing antiseptic facial mask are antibacterial agent and preservative, general utility functions are to inhibit bacterial growth, function is more single, therapeutic effect is not ideal enough, and there are the security risks being used for a long time in a large amount of preservative addition, with antibacterial action, and there is moisturizing, promote wound healing, reduce the effect of scar, perfect in shape and function, and be free of preservative, it can be used for a long time, securely and reliably.
Description
Technical field
The present invention relates to facial mask field, in particular to a kind of micro-current antibacterial facial mask.
Background technique
After facial mask spreads on face, skin can be temporarily isolated from the outside, the substance in facial mask will tightly wrap skin
It wraps up in, allows skin and the air barrier in the external world to open, on the one hand allow moisture content gently to infiltrate through the cuticula of epidermis, allow the thin of cuticula
Born of the same parents " are full water " in wet environment, and deep layer cells is made to suction moisture content, such skin will softness get up, increase elasticity；With
This simultaneously, skin surface can also warm up, promote telangiectasis, be advantageous in this way be infected in pore the external world ash
Dirt, chemical pollutant and microorganism are removed, and are also beneficial to exclude the waste and accumulate that epidermal cell metabolism generates
More oil substances.
The general main function ingredient of antiseptic facial mask type is antibacterial agent and preservative at present, and general utility functions are to inhibit
Bacterial growth, function is more single, and therapeutic effect is not ideal enough, and a large amount of preservative addition has the safety being used for a long time
Risk, and the mask substrate that conventional facial mask type dressing uses is only capable of playing the role of film liquid carrier for normal film cloth.
Summary of the invention
Present invention aim to address the functional components of existing antiseptic facial mask be antibacterial agent and preservative, generally
Function is to inhibit bacterial growth, and function is more single, and therapeutic effect is not ideal enough, and the addition of a large amount of preservative exists and makes for a long time
Security risks, and the mask substrate that conventional facial mask type dressing uses is only capable of playing the work of film liquid carrier for normal film cloth
With providing one kind has antibacterial action containing tridecanoic peptide and hyaluronic acid antibacterial facial mask, and has moisturizing, promotes wound healing
It closes, reduces the effect of scar, perfect in shape and function, and be free of preservative, can be used for a long time, securely and reliably, will be added in mask substrate
Conductive micro-current conducting wire, external wear biology micro-current generator make mask substrate have biological micro-current, promote face new
Old metabolism and blood circulation promote the absorption of substance in facial mask base fluid.
Technical solution provided by the invention are as follows:
A kind of micro-current antibacterial facial mask, including mask substrate, facial mask essence and the micro- electric generating system of biology, the facial mask
Essence includes thickener, moisturizer, bleeding agent, glycerol, tridecanoic peptide, neutralizer and purified water, arrangement in the mask substrate
There is micro-current conducting wire, the micro- electric generating system of the biology includes the micro- electric generator of biology and micro-current conducting wire.
Preferably, the mask substrate material is non-woven fabrics, and the micro-current conducting wire is the silver that diameter is 32 strands 2 μm
Silk is wrapped up by silk thread, and the micro-current conducting wire is uniformly embedded in mask substrate.
Preferably, the micro- electric generator of the biology issues micro-current and is divided into six sections, and respectively first low section, in second
Section, high section, the second middle section, second low section, ending segment.
Preferably, it is flowed 3 seconds for powers failure in 1 second of constant pressure 13.5V high current for described first low section, operation 5 minutes, described the
Two middle section constant pressure 13.5V high current power failures in 2 seconds, which are flowed 2 seconds, to be run 5 minutes, and the high section is constant pressure 13.5V high current power failure in 3 seconds stream
It runs 5 minutes within 1 second, the second middle section is that operation in 2 seconds 5 minutes is flowed in the power failure in 2 seconds of constant pressure 13.5V high current, and second low section is constant pressure
The power failure in 1 second of 13.5V high current, which is flowed 3 seconds, to be run 5 minutes, and ending segment is constant pressure 7V high current 5 minutes.
Preferably, it is provided with crimp head on the micro- electric generator positive and negative anodes of the biology, the crimp head is by conductive rubber
It is made.
Preferably, the wearing mode of the micro- electric generator of biology is supra-aural.
Preferably, the facial mask essence weight percentage, including following components: thickener 0.15-
1.5%, moisturizer: 0.1-1%, bleeding agent: 0.1-1%, glycerol: 5%, tridecanoic peptide 15-20%, neutralizer: 0.15%, remaining
Amount: purified water.
Preferably, the molecular formula of the tridecanoic peptide are as follows:
Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Ile-Cys-Tyr-Arg-Cys, the thickener are card wave
Nurse, the moisturizer are polymer hyaluronic acid and low molecular weight hyaluronic acid, and the bleeding agent is butanediol, and the neutralizer is
Triethanolamine.
A kind of production method preparing micro-current antibacterial facial mask, this method include the following steps:
Step 1
The preparation of facial mask essence；
Step 2
Filamentary silver is pressed into mask substrate；
Step 3
It is mixed with appropriate facial mask essence by mask substrate is compound, folding is put into packaging bag and is packaged.
Preferably, in the step 1 facial mask essence specific operation process are as follows:
1) tridecanoic peptide purified Activity determination；
2) purified water is added in a reservoir；
3) carbomer, polymer hyaluronic acid, low molecular weight hyaluronic acid are sequentially added into container, stir 10 minutes extremely
It is uniformly dispersed；
4) liquid of step 3 is added in homogenizer, temperature maintains 60-75 DEG C, and homogenizer carries out high speed homogenization 10 and divides
Clock, until whole system clear, grainless solid component, are cooled to room temperature；
5) glycerol is added into container, is sufficiently stirred 10 minutes to uniform；
6) tridecanoic peptide is added, is sufficiently stirred 10 minutes to uniform；
7) it is slowly added to triethanolamine into container, stirs while adding, stirs evenly；
8) 135 DEG C of high-temperature short-time sterilizations are used, quality inspection is carried out.
The invention has the following advantages:
1, the present invention is had verified that using tridecanoic peptide and hyaluronic acid antibacterial facial mask, tridecanoic peptide is contained with antibacterial action,
Preservative can be replaced, makes the present invention without preservative, can be used for a long time, securely and reliably, and tridecanoic peptide has moisturizing, promotes wound
Healing, reduces the effect of scar, and tridecanoic peptide and hyaluronic acid cooperation have the effects that moisturizing, reduce acne and reduce scar, function
It is good that effect can be improved.
2, the present invention is occurred using conductive micro-current conducting wire, external wear biology micro-current will be added in mask substrate
Device makes mask substrate have biological micro-current, promotes face metabolism and blood circulation, promotes the suction of substance in facial mask base fluid
It receives.
3, the present invention is issued micro-current and is divided into six sections using biological micro-current generator, the micro- electric generator of biology, often
Section electric current reasonable employment constant voltage and electric current and reasonable action time, the biological microcurrent stimulating for having mask substrate
Within the appropriate range, make biological micro-current appropriate to the stimulation of face, keep the assimilation effect of substance in facial mask base fluid more preferable.
Specific embodiment
The present invention is described in further detail below, to enable those skilled in the art's refer to the instruction text being capable of evidence
To implement.
Embodiment 1
A kind of micro-current antibacterial facial mask, including mask substrate, facial mask essence and the micro- electric generating system of biology, the facial mask
Essence includes thickener, moisturizer, bleeding agent, glycerol, tridecanoic peptide, neutralizer and purified water, arrangement in the mask substrate
There is micro-current conducting wire, the micro- electric generating system of the biology includes the micro- electric generator of biology and micro-current conducting wire.
The mask substrate material is non-woven fabrics, and the micro-current conducting wire is filamentary silver that diameter is 32 strands 2 μm by silk thread packet
It wraps up in, the micro-current conducting wire is uniformly embedded in mask substrate.
The micro- electric generator of the biology issues micro-current and is divided into six sections, and respectively first low section, the second middle section, high section, the
Two middle sections, second low section, ending segment.
Cell voltage 3.7V quiescent current 0.01uA on micro-current generator clicks micro-current generator switch, instruction
On the bright 5mS of lamp, DC/DC circuit work output 13.5V electric current 100uA to electrode facial mask
Described first low section is constant pressure 13.5V, and electric current 100uA1 seconds, electric current 0uA 3 seconds, this process operation 5 minutes was described
Second middle section constant pressure 13.5V, electric current 100uA2 seconds, electric current 0uA2 seconds, this process operation 5 minutes, the high section was constant pressure
13.5V, electric current 100uA3 seconds, electric current 0uA1 seconds, this process operation 5 minutes, the second middle section was constant pressure 13.5V, electric current 100uA2
Second, 0uA electric current 2 seconds, this process operation 5 minutes, second low section be constant pressure 13.5V, electric current 100uA1 seconds, 0uA electric current 3 seconds, this
Process operation 5 minutes, ending segment was constant pressure 7V, electric current 50uA, persistently delayed degree stimulation skin, this process operation 5 minutes.
It is provided with crimp head on the micro- electric generator positive and negative anodes of biology, the crimp head is made of conductive rubber.
The facial mask essence weight percentage, including following components: thickener 0.15%, moisturizer:
0.1%, bleeding agent: 0.1%, glycerol: 5%, tridecanoic peptide 15%, neutralizer: 0.15%, surplus: purified water.
The molecular formula of the tridecanoic peptide are as follows:
Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Ile-Cys-Tyr-Arg-Cys, the thickener are card wave
Nurse, the moisturizer are polymer hyaluronic acid and low molecular weight hyaluronic acid, and the bleeding agent is butanediol, and the neutralizer is
Triethanolamine.
A kind of production method preparing micro-current antibacterial facial mask, this method include the following steps:
Step 1
The preparation of facial mask essence；
Step 2
Filamentary silver is pressed into mask substrate；
Step 3
It is mixed with appropriate facial mask essence by mask substrate is compound, folding is put into packaging bag and is packaged.
The specific operation process that in the step 1 prepared by facial mask essence are as follows:
1) tridecanoic peptide purified Activity determination；
2) purified water is added in a reservoir；
3) carbomer, polymer hyaluronic acid, low molecular weight hyaluronic acid are sequentially added into container, are extremely divided within stirring 10 minutes
It dissipates uniform；
4) liquid of step 3 is added in homogenizer, temperature maintains 60-75 DEG C, and homogenizer carries out high speed homogenization 10 and divides
Clock, until whole system clear, grainless solid component, are cooled to room temperature；
5) glycerol is added into container, is sufficiently stirred 10 minutes to uniform；
6) tridecanoic peptide is added, is sufficiently stirred 10 minutes to uniform；
7) it is slowly added to triethanolamine into container, stirs while adding, stirs evenly；
8) 135 DEG C of high-temperature short-time sterilizations are used, quality inspection is carried out.
The micro-current conducting wire is evenly distributed in mask substrate, and the micro-current conducting wire is sewed with silk thread in mask substrate
Interior, the wearing mode of the micro- electric generator of biology is supra-aural, with applicator ring on the micro- electric generator of biology, when use
The micro- electric generator of biology is worn on ear, mask substrate is taken out, applies on the face, the both ends of filamentary silver on facial mask is crimped respectively
Onto the crimp head at the micro- positive and negative the two poles of the earth of electric generator of biology, the micro- electric generator of biology, the micro- electric generator stable operation of biology are opened
Six sections of electric currents remove mask substrate and the micro- electric generator of biology after the predetermined time, and the mask substrate is disposable
It uses, the micro- electric generator internal control circuit of biology is controlled with MCU, be can be recycled.
Embodiment 2
A kind of micro-current antibacterial facial mask, including mask substrate, facial mask essence and the micro- electric generating system of biology, the facial mask
Essence includes thickener, moisturizer, bleeding agent, glycerol, tridecanoic peptide, neutralizer and purified water, arrangement in the mask substrate
There is micro-current conducting wire, the micro- electric generating system of the biology includes the micro- electric generator of biology and micro-current conducting wire.
The mask substrate material is non-woven fabrics, and the micro-current conducting wire is filamentary silver that diameter is 32 strands 2 μm by silk thread packet
It wraps up in, the micro-current conducting wire is uniformly embedded in mask substrate.
The micro- electric generator of the biology issues micro-current and is divided into six sections, and respectively first low section, the second middle section, high section, the
Two middle sections, second low section, ending segment.
Cell voltage 3.7V quiescent current 0.01uA on micro-current generator clicks micro-current generator switch, instruction
On the bright 5mS of lamp, DC/DC circuit work output 13.5V electric current 100uA to electrode facial mask
Described first low section is constant pressure 13.5V, and electric current 100uA1 seconds, electric current 0uA 3 seconds, this process operation 5 minutes was described
Second middle section constant pressure 13.5V, electric current 100uA2 seconds, electric current 0uA 2 seconds, this process operation 5 minutes, the high section was constant pressure
13.5V, electric current 100uA 3 seconds, electric current 0uA1 seconds, this process operation 5 minutes, the second middle section was constant pressure 13.5V, electric current 100uA
2 seconds, 0uA electric current 2 seconds, this process operation 5 minutes, second low section be constant pressure 13.5V, electric current 100uA 1 second, 0uA electric current 3 seconds,
This process operation 5 minutes, ending segment are constant pressure 7V, electric current 50uA, persistently delay degree stimulation skin, this process operation 5 minutes.
It is provided with crimp head on the micro- electric generator positive and negative anodes of biology, the crimp head is made of conductive rubber.
The facial mask essence weight percentage, including following components: it thickener 1.5%, moisturizer: 1%, seeps
Saturating agent: 1%, glycerol: 5%, tridecanoic peptide 20%, neutralizer: 0.15%, surplus: purified water.
The molecular formula of the tridecanoic peptide are as follows:
Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Ile-Cys-Tyr-Arg-Cys, the thickener are card wave
Nurse, the moisturizer are polymer hyaluronic acid and low molecular weight hyaluronic acid, and the bleeding agent is butanediol, and the neutralizer is
Triethanolamine.
A kind of production method preparing micro-current antibacterial facial mask, this method include the following steps:
Step 1
The preparation of facial mask essence；
Step 2
Filamentary silver is pressed into mask substrate；
Step 3
It is mixed with appropriate facial mask essence by mask substrate is compound, folding is put into packaging bag and is packaged.
The specific operation process that in the step 1 prepared by facial mask essence are as follows:
1) tridecanoic peptide purified Activity determination；
2) purified water is added in a reservoir；
3) carbomer, polymer hyaluronic acid, low molecular weight hyaluronic acid are sequentially added into container, are extremely divided within stirring 10 minutes
It dissipates uniform；
4) liquid of step 3 is added in homogenizer, temperature maintains 60-75 DEG C, and homogenizer carries out high speed homogenization 10 and divides
Clock, until whole system clear, grainless solid component, are cooled to room temperature；
5) glycerol is added into container, is sufficiently stirred 10 minutes to uniform；
6) tridecanoic peptide is added, is sufficiently stirred 10 minutes to uniform；
7) it is slowly added to triethanolamine into container, stirs while adding, stirs evenly；
8) 135 DEG C of high-temperature short-time sterilizations are used, quality inspection is carried out.
The micro-current conducting wire is evenly distributed in mask substrate, and the micro-current conducting wire is sewed with silk thread in mask substrate
Interior, the wearing mode of the micro- electric generator of biology is supra-aural, with applicator ring on the micro- electric generator of biology, when use
The micro- electric generator of biology is worn on ear, mask substrate is taken out, applies on the face, the both ends of filamentary silver on facial mask is crimped respectively
Onto the crimp head at the micro- positive and negative the two poles of the earth of electric generator of biology, the micro- electric generator of biology, the micro- electric generator stable operation of biology are opened
Six sections of electric currents remove mask substrate and the micro- electric generator of biology after the predetermined time, and the mask substrate is disposable
It uses, the micro- electric generator internal control circuit of biology is controlled with MCU, be can be recycled.
Preservation and usage: facial mask of the present invention can be placed and be saved in a cool and dry place, and temperature is not higher than 38 DEG C.Existed using preceding elder generation
Skin is on probation after the back of the hand or ear, and no sensitive subjects can be suitable for skin of face.In use, uniformly applying facial mask of the present invention in face
Portion, 3 times a week.
Clinical test is carried out to micro-current antibacterial facial mask fungistatic effect:
Clinical general information (selection of disease, total cases and case):
Subject totally 30 of Pass Test condition are included in this test.Concrete condition is described as follows:
1. inclusion criteria
1.1 voluntary participation；
4~60 one full year of life of 1.2 age, men and women are unlimited；
1.3 clinical diagnosises are chronic dermatitis, eczema, after cosmetology, skin diseases such as damaged skin after shining；
1.4 skin lesions are in skin surface；
1.5 patients such as use other external drugs or oral drug therapy, need to deactivate 10 days or more persons；
2. exclusion criteria
2.1 have serious systemic disease patient, including the heart, liver, kidney, metabolism and endocrine, hematological system, autoimmune disease
Disease and malignant tumour etc.；
2.2 is known or suspicious to this product ingredient allergy sufferers；
2.3 must clinically receive the patient of other therapies.
Test method: selection meets subject 30 of this experimental condition, directly wet with containing to micro-current antibacterial facial mask
It spreads in skin lesion 1-3 times daily.
Used statistical method and evaluation method:
Statistical method: using analysis of cases method, and judgement contains the clinical use curative effect to micro-current antibacterial facial mask.
Evaluation method:
For statistical analysis to the effective percentage containing micro-current antibacterial facial mask, test group total effective rate is more than 85%
Assert effective.
Evaluation criterion:
Improve the functional evaluation of inflammatory reaction: pressing symptom: itch.Sign: erythema, the scales of skin that peel off.Standards of grading: 0~3 point is pressed
Meter.Therapeutic index=(pre-treatment score-post treatment integral)/pre-treatment score × 100%.Complete incidence graph be therapeutic index >=
90%；Significant alleviate is therapeutic index >=50%；Minor responses are therapeutic index >=20%；It is in vain therapeutic index < 20%.
Effective percentage is calculated with complete incidence graph+significant alleviate.
8 clinical test results of table
The adverse events and side effect and its disposition found in clinical test: it is not found during entire clinical test
Adverse events and side effect.
Clinical trial result analysis:
After the sensitive skin such as the case majority that this clinical test selects is dermatitis, eczema and cosmetology, after solarization and object
Damaged skin caused by reason, chemistry etc. stimulate, the decline of skin moisture-keeping ability, skin physiology moisture is largely lost, between epidermal cell
Gap increases, and environmental stimuli is easy for penetrating skin barrier intrusion skin, further induces scytitis, extends skin disease
Treatment time, while over-drying surface of a wound environment not only leads to pruitus, influences patients ' life quality, and repeatedly
Scratching will lead to scytitis recurrent exerbation, this test contains the antibacterials such as tridecanoic peptide using micro-current antibacterial facial mask as trial target
Anti-inflammatory, substance wound healing, repaired skin barrier, improve skin and mucosa-immune power, accelerate by microcurrent stimulating
Facial blood circulation promotes the absorption of various substances and moisture, can be effectively improved patient skin drying, furfur phenomenon, promote
Inflammatory resolution.Damaged skin barrier is repaired, damage of the environmental stimuli to skin is reduced, plays anti-inflammatory, anti-allergic effects, while can
To reduce pigmented generation.
Clinical test conclusion:
Clinical test results show: the present invention is 100% to symptom of erythema effective percentage is improved, and is improved to furfur symptom effective
Rate is 100%, and improving efficient to pruritis is 100%, and test result shows: this product can improve dermatitis, eczema, sensibility
Decortication, erythema, pruritis caused by skin, for the moisturizing restoration care after beauty, orthopedic；Skin barrier is repaired, is promoted
Into wound healing.
Do not occur an example infection and adverse reaction in clinical verification simultaneously, the facial case that this tests selection is more, examination
Tender area skin thin for face etc. does not occur pessimal stimulation during testing.
Illustrate that the clinical use of micro-current antibacterial facial mask has safety and validity.
Although the embodiments of the present invention have been disclosed as above, but its is not only in the description and the implementation listed
With.It can be applied to various suitable the field of the invention completely.It for those skilled in the art, can be easily
Realize other modification.Therefore without departing from the general concept defined in the claims and the equivalent scope, the present invention is simultaneously unlimited
In specific details and legend shown and described herein.
Claims (10)
1. a kind of micro-current antibacterial facial mask, which is characterized in that be including mask substrate, facial mask essence and the micro- electricity of biology
System, the facial mask essence includes thickener, moisturizer, bleeding agent, glycerol, tridecanoic peptide, neutralizer and purified water, the face
Micro-current conducting wire is disposed in film base fabric, the micro- electric generating system of the biology includes the micro- electric generator of biology and micro-current conducting wire.
2. a kind of micro-current antibacterial facial mask according to claim 1, which is characterized in that the mask substrate material is nonwoven
Cloth, the micro-current conducting wire are that the filamentary silver that diameter is 32 strands 2 μm is wrapped up by silk thread, and the micro-current conducting wire is uniformly embedded in
In mask substrate.
3. a kind of micro-current antibacterial facial mask according to claim 1, which is characterized in that the micro- electric generator of biology issues
Micro-current is divided into six sections, and respectively first low section, the second middle section, high section, the second middle section, second low section, ending segment.
4. a kind of micro-current antibacterial facial mask according to claim 3, which is characterized in that described first low section is constant pressure
The power failure in 1 second of 13.5V high current is flowed 3 seconds, is run 5 minutes, the second middle section constant pressure 13.5V high current power failure in 2 seconds, which is flowed 2 seconds, transports
Row 5 minutes, the high section was that operation in 1 second 5 minutes is flowed in the power failure in 3 seconds of constant pressure 13.5V high current, and the second middle section is constant pressure 13.5V high
Electric current power failure in 2 seconds is flowed to be run 5 minutes for 2 seconds, and second low section is flowed operation in 3 seconds 5 minutes for the power failure in 1 second of constant pressure 13.5V high current, is terminated
Section is constant pressure 7V high current 5 minutes.
5. a kind of micro-current antibacterial facial mask according to claim 1, which is characterized in that the micro- electric generator of biology is positive and negative
Crimp head is provided on extremely, the crimp head is made of conductive rubber.
6. a kind of micro-current antibacterial facial mask according to claim 1, which is characterized in that the pendant of the micro- electric generator of biology
Wearing mode is supra-aural.
7. a kind of micro-current antibacterial facial mask according to claim 1, which is characterized in that the facial mask essence by weight hundred
Divide content meter, including following components: thickener 0.15-1.5%, moisturizer: 0.1-1%, bleeding agent: 0.1-1%, glycerol:
5%, tridecanoic peptide 15-20%, neutralizer: 0.15%, surplus: purified water.
8. a kind of micro-current antibacterial facial mask according to claim 7, which is characterized in that the molecular formula of the tridecanoic peptide are as follows:
Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Ile-Cys-Tyr-Arg-Cys, the thickener are carbomer, institute
Stating moisturizer is polymer hyaluronic acid and low molecular weight hyaluronic acid, and the bleeding agent is butanediol, and the neutralizer is three second
Hydramine.
9. a kind of production method for preparing micro-current antibacterial facial mask described in claim 1-8 any one claim, special
Sign is that this method includes the following steps:
Step 1
The preparation of facial mask essence；
Step 2
Filamentary silver is pressed into mask substrate；
Step 3
It is mixed with appropriate facial mask essence by mask substrate is compound, folding is put into packaging bag and is packaged.
10. a kind of production method of micro-current antibacterial facial mask, which is characterized in that the concrete operations of facial mask essence in the step 1
Process are as follows:
1) tridecanoic peptide purified Activity determination；
2) purified water is added in a reservoir；
3) carbomer, polymer hyaluronic acid, low molecular weight hyaluronic acid are sequentially added into container, stirring 10 minutes equal to dispersing
It is even；
4) liquid of step 3 being added in homogenizer, temperature maintains 60-75 DEG C, and homogenizer carries out high speed homogenization 10 minutes, until
Whole system clear, grainless solid component, is cooled to room temperature；
5) glycerol is added into container, is sufficiently stirred 10 minutes to uniform；
6) tridecanoic peptide is added, is sufficiently stirred 10 minutes to uniform；
7) it is slowly added to triethanolamine into container, stirs while adding, stirs evenly；
8) 135 DEG C of high-temperature short-time sterilizations are used, quality inspection is carried out.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910747882.0A CN110522668A (en) | 2019-08-14 | 2019-08-14 | A kind of micro-current antibacterial facial mask and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910747882.0A CN110522668A (en) | 2019-08-14 | 2019-08-14 | A kind of micro-current antibacterial facial mask and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110522668A true CN110522668A (en) | 2019-12-03 |
Family
ID=68663038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910747882.0A Withdrawn CN110522668A (en) | 2019-08-14 | 2019-08-14 | A kind of micro-current antibacterial facial mask and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110522668A (en) |
-
2019
- 2019-08-14 CN CN201910747882.0A patent/CN110522668A/en not_active Withdrawn
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