JPH05310597A - Agent for contact treatment - Google Patents

Abstract

PURPOSE:To provide a contact treatment agent composed of a compound having electron-accepting structure in the molecule and allowable to be contacted with the surface of human skin, capable of absorbing abnormal potential on the skin, effective for the treatment of muscle ache, shoulder discomfort, etc., effective for wrinkle smoothing, hair growing, etc., and used by contacting with the skin. CONSTITUTION:The objective contact treatment agent is effective in absorbing abnormal potential to eliminate the ache by contacting with the skin, increasing the blood flow rate to eliminate the substance causative of ache and the fatigue substance retained in the capillary vessel and removing the pain and fatigue. The agent can be produced by using quinone, furan, furfural, pyrrole, thiophene, phthalocyanine, chlorophyll, hemoglobin, hemocyanine or their derivatives as a compound having electron accepting structure in the molecule and, for example, kneading the compound in an electrically conductive plastic and applying to the skin as a plaster, compounding the compound in an ointment, poultice, cream, pack, rinse, hair liquid or pomade or using as a component of a bathing agent.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a contact therapeutic agent which is used in contact with the skin for the treatment of muscle pain, stiff shoulders, wrinkles, hair growth and the like.

[0002]

2. Description of the Related Art Conventionally, in order to treat muscle pain, stiff shoulders, etc., in addition to acupuncture, an electric treatment device, a magnetic treatment device, a semiconductor treatment device, etc. have been used.

[0003]

However, since all of the electric treatment device, the magnetic treatment device, the semiconductor treatment device and the like fix the molded body to the skin with plaster or the like, the pressing stimulus is too large and the plaster is applied to the plaster. There was a risk of rashes, and there was the problem that it looked bad. The present invention is to solve such a problem in a therapeutic device for muscle pain, stiff shoulder, etc., and has a good therapeutic effect, in addition to the treatment of muscle pain, stiff shoulder, etc., it is also effective for wrinkle removal, hair growth, etc. It is an object to provide a contact therapeutic agent that can be used in a discreet state.

[0004]

[Means for Solving the Problems] Normally, the front side of human epidermis is negatively polarized and the back side is positively polarized. When a p-type semiconductor is brought into contact with a portion of skin where an abnormal potential is generated, Abnormal potential is absorbed and pain is resolved. Further, according to the measurement using a thermography or a laser speckle blood flow meter, it is recognized that the blood flow is increased when the semiconductor is brought into contact with the skin. It is considered that if the blood flow is increased, the pain-causing substance and the fatigue substance accumulated in the capillaries are removed, so that muscle pain and stiffness are eliminated. Semiconductors include p-type semiconductors and n-type semiconductors, and when p-type and n-type powdery semiconductors are applied to the skin and a therapeutic test for muscle pain is performed,
A remarkable effect is recognized in the p-type semiconductor. The powdery p-type semiconductor can also be used for wrinkle removal and hair growth, which have been difficult with conventional semiconductor treatment devices.

The present inventor has conducted similar tests using a compound having an electron accepting structure in the molecule, and has found that it has the same effect as a p-type semiconductor. The electron-accepting structure refers to a structure of an atom, molecule, or ion that easily accepts an electron from the other party. For example, in a so-called quinhydrone, which is an intermolecular compound between hydroquinone and benzoquinone, hydroquinone is an electron. And benzoquinone accepts an electron. As an electron acceptor having such an electron accepting structure, halogen such as iodine, various quinones, trinitrobenzene and the like are known. When these electron acceptors come into close contact with the body, they receive an abnormal negative potential on the body surface like the p-type semiconductor, and thus activate muscles.

The present invention has been made based on the above findings, and solves the above-mentioned problems by composing a contact therapeutic agent with a compound capable of contacting the skin surface of the human body and having an electron accepting structure in the molecule. is doing. As compounds having an electron accepting structure in the molecule, in addition to quinone, furan [Fig. 2 (A)] and furfural [Fig.
(B)], pyrrole [Fig. 2 (C)], thiophene [Fig. 2]
(D)] and phthalocyanine [Fig. 2 (E, F)].
As a compound having an electron accepting structure in a natural molecule,
Some compounds have a porphyrin ring, such as chlorophyll, hemoglobin, and hemocyanin. The porphyrin ring is
As shown in FIG. 3 (A), four pyrroles are [= CH
₂₋ ] has a ring structure connected to each other, in which Mg,
Metals such as Fe and Cu combine to form chlorophyll [Fig.
(B)], hemoglobin [FIG. 3 (C)], and hemocyanin (not shown) are formed. When viewed electronically, the porphyrin ring is an electron acceptor, and a metal such as Mg, Fe, or Cu is an electron donor, and the electron acceptor and the electron donor coexist in the same molecule. However, also in this case, the above effect is sufficiently realized. This is because the electron donor does not react to the negative electricity on the skin surface in the area where the electron donor comes into contact with the skin, so the above effect can be obtained if the electron acceptor comes into contact with the skin. Is. Therefore, any compound having an electron accepting structure in the molecule may coexist with a compound having an electron donating structure.

This contact therapeutic agent can be used by kneading it in a conductive plastic and applying it with plaster, applying it in a patch, putting it in a poultice, putting it in a cream, putting it in a pack, or putting it in a rinse. The method, the method of putting it in a hair liquid or pomade, the method of putting it in a bathing agent and the like are possible and can be widely used.

[0008]

[Function] A compound having an electron-accepting structure in the molecule has a property of attracting an electron and repelling a positive charge. Normal,
The front side of the human epidermis is negatively polarized and the back side is positively polarized, and there is a potential difference of several tens of millivolts, and when this becomes large, it causes pain. In the case of acupuncture, it is said that when an acupuncture needle is inserted under the skin, the front surface and the back surface of the skin are electrically short-circuited, so that the abnormal potential disappears and the pain disappears. When a compound having an electron-accepting structure in the molecule is brought into contact with a portion of the skin where an abnormal electric potential is generated, negative electricity (electrons) is attracted to eliminate the abnormal electric potential on the surface. When the abnormal potential on the surface is eliminated, the back potential, which has a dielectric relationship between the epidermis, returns to normal, and the muscle pain associated with the abnormal potential is eliminated and the muscle is activated. A compound having an electron-accepting structure that absorbs negative electricity is discharged to clothes or the like and returns to the original state with time.

Another action of the compound having an electron accepting structure in the molecule is to increase blood flow. Blood that supplies oxygen and nutrients to the terminal tissues dissolves carbon dioxide and waste products and returns from the veins to the heart. At this time, the veins send blood by pulsation, and the compound having an electron accepting structure activates the pulsation of the veins and prevents muscle aging. Generally, stiffness, wrinkles, hair loss, etc. are considered to be caused by aging, such as a decrease in blood flow inside the skin and a decrease in water retention of the skin.
By activating the inside of the skin using a compound having an electron-accepting structure, excellent effects can be obtained in muscle pain, stiff shoulder, wrinkle removal, hair growth and the like.

[0010]

【Example】

(Example 1) 0.2 g of copper chlorophyllin sodium for food additives was kneaded into 20 g of Shiseido's Elixir treatment mask, applied to a commercially available first-aid bandage fabric, and dried. Severe shoulder stiffness patient 4 who does not raise this arm
Name, shoulders of 5 patients with moderate stiff shoulder, big bones, Magaki, Tenmune,
It was attached to each meridian of Chufu and Kumon after bathing every day. After 1 week, all the severely ill patients were completely relieved, 80% recovered in 1 person, 1 was slightly improved, 3 in moderately ill patients were recovered, 80% recovered in 1 person, 50% in 1 person
It was recovered and the effect rate was 79%.

(Example 2) 0.2 g of P-benzoquinone was kneaded into 20 g of epoxy resin and solidified at room temperature into a hemisphere having a diameter of about 5 mm. A round plaster with a diameter of about 5 mm was applied to the tender points of each meridian of Jojo, Renyu, Shimuro, Colon Yu and Seki Motoyu for 3 patients with severe low back pain and 5 patients with moderate low back pain. After sticking for 3 days, it was taken once, left one day, and stuck again for 3 days. 2 severely ill patients, 1 unchanged, 3 moderately ill patients, 1% 80% recovery, 1 slightly recovery, 7 effective rate
It was 3%.

Example 3 0.2 g of copper chlorophyllin sodium for food addition was dissolved in 70 g of Sophina Moisture Pack manufactured by Kao. When this pack was packed by 5 women, 3 wrinkled under the corners of the eyes and 1 wrinkled on the forehead. (Example 4) After 0.1 g of copper phthalocyanine was mixed with 20 g of Shiseido's Elixir treatment mask and kneaded well, the three patients with arm pain, Tezuri, Kageike, Gokusen, Kosai, Yudama and Shakusawa Each meridian was applied after bathing. Six days later, the two had almost recovered, and the other one had a 50% recovery.

(Example 5) 0.5 g of copper chlorophyllin sodium for food addition was added to a bath having a capacity of about 1 t, and one back pain patient and one neuralgia patient took a bath for about one month. The progress was good and almost improved. (Example 6) 0.5 g of furan was added to Yanagiya Hair Tonic 20.
It was mixed with g and used as a hair restorer. One slightly thinning hair started to grow in about one month, and the other one started growing in 1.5 months.

[0014]

As described above, the contact therapeutic agent of the present invention has a good effect because it uses a compound having an electron-accepting structure in the molecule. In addition to the treatment of muscle soreness, stiff shoulders, etc., wrinkle removal and hair growth It is also effective for It can also be used in a wide variety of ways.

[Brief description of drawings]

FIG. 1 is a diagram showing a structural formula of (A) ortho-benzoquinone. It is a figure which shows the structural formula of (B) para-benzoquinone.

FIG. 2 is a diagram showing the structural formula of (A) furan. It is a figure which shows the structural formula of (B) furfural. It is a figure which shows the structural formula of (C) pyrrole. It is a figure which shows the structural formula of (D) thiophene. It is a figure which shows the structural formula of (E) phthalocyanine ring. It is a figure which shows the structural formula of (F) phthalocyanine blue.

FIG. 3 is a diagram showing a structural formula of a porphyrin ring (A). It is a figure which shows the structural formula of (B) chlorophyll A. It is a figure which shows the structural formula of (C) hemoglobin.

Front page continuation (51) Int.Cl. ⁵ Identification code Office reference number FI Technical display location A61K 31/40 ADA 7252-4C 31/555 7252-4C C07D 307/28 307/48 333/10

Claims (3)

[Claims] 1. A contact therapeutic agent comprising a compound capable of contacting the skin surface of a human body and having an electron accepting structure in the molecule. 2. The therapeutic agent for contact according to claim 1, wherein the compound having an electron accepting structure in the molecule is quinone, furan, furfural, pyrrole, thiophene, phthalocyanine, or a derivative thereof. 3. The contact therapeutic agent according to claim 1, wherein the compound having an electron accepting structure in the molecule is chlorophyll, hemoglobin, hemocyanin, or a derivative thereof.