CN1104534A

CN1104534A - Yinweichengong instant powder

Info

Publication number: CN1104534A
Application number: CN 94110695
Authority: CN
Inventors: 沙芝泉; 雷志英
Original assignee: Individual
Current assignee: Individual
Priority date: 1994-07-20
Filing date: 1994-07-20
Publication date: 1995-07-05

Abstract

The instant particles for preventing and curing angina pectoris, myocardial infarction, coronary heart disease, hyperlipemia, climacteric syndrome, senile dementia, etc. is prepared through such steps as immersing corn pollen in water adding gingko leaves, decocting, filtering and concentrating to obtain the extract; extracting the haw refluently by alcohol, filtering and concentrating to obtain another extract; mixing, adding VE, and granulating.

Description

Yinweichengong instant powder

The invention belongs to the technical field of the medicinal preparation of the material that derives from plant.

The Chinese patent medicine that is used for the treatment of arteriosclerosis, hyperlipidemia, angina pectoris, myocardial infarction and coronary heart disease at present has " SHUXUENING PIAN " recorded in Beijing's drug standard nineteen eighty-three version volume two, record in " XINKESHU PIAN " of Shandong pharmacopeia version in 1986, record in " FUFANG DANSHEN PIAN " of one one of Chinese Pharmacopoeia nineteen ninety version.But these medicines can only be used for blood vessel dilating, blood circulation promoting and blood stasis dispelling, comfortable blood pressure lowering, regulating QI to relieve pain, and can not strengthen body immunity simultaneously, enhance metabolism, postpone cell senescence, slow down aging and alleviate the gonad atrophy, the prevention cardiovascular and cerebrovascular disease, can not treat senile dementia, climacteric syndrome.

The purpose of this invention is to provide a kind of prevention and treatment cardiovascular and cerebrovascular disease, treatment senile dementia, climacteric syndrome, and strengthen medicine of body immunity, slow down aging and preparation method thereof.

This Yinweichengong instant powder, comprise Folium Ginkgo, Fructus Crataegi, vitamin E, it is characterized in that also comprising Pollen Maydis, and the ratio of weight and number of its used medicine components is: Fructus Crataegi: Folium Ginkgo: Pollen Maydis: vitamin E=1: 0.45-13.5: 0.7-16: 0.0005-0.05.

The manufacture method of this Yinweichengong instant powder is carried out according to the following steps;

A, by the ratio of weight and number of its used medicine components, it is standby to get 1 part of Fructus Crataegi, Folium Ginkgo 0.45-13.5 part, Pollen Maydis 0.7-16 part, vitamin E 0.0005-0.05 part,

B, get Pollen Maydis.After in excessive water, soaking, put into Folium Ginkgo, decoct, filter, get the filtrate of impurity such as gummy, natural cooling,

C, treat that the filtrate temperature is reduced to room temperature after, place subambient environment cold preservation to contamination precipitations such as natural gum to separate out, filter, gained filtrate is concentrated into 1.15-1.45g/cm ³(90-95 ℃) gets clear paste,

D, get Fructus Crataegi, use alcohol reflux, filter, the filtrate that gained contains impurity such as pectin places subambient environment cold preservation, separates out to impurity such as pectin, filter, filtrate, behind the filtrate recycling ethanol, be concentrated into 1.15-1.45g/cm ³(60-85 ℃) gets clear paste,

E, above-mentioned c gained clear paste is mixed with above-mentioned d gained clear paste, must mix clear paste, add the Icing Sugar that mixes one times of clear paste weight and one times dextrin, take the dissolved vitamin E of small amount of ethanol again, mix, make granule with the above-mentioned clear paste, Icing Sugar, dextrin of mixing.

Pollen Maydis has the enhancing body immunity, improves the resistivity of human body to various diseases, improves cardiovascular and cerebrovascular circulation, the effect of life prolonging; Folium Ginkgo have relieving asthma, pain relieving, be used for the treatment of the deficiency of the lung, cough with asthma, coronary heart disease, angina pectoris etc., and Fructus Crataegi can help digestion, strengthening the spleen and stomach, circulation of qi promoting dissipating blood stasis, can treat hyperlipidemia; Vitamin E can enhance metabolism, postpone cell senescence, slow down aging, and angiocardiopathy preventing, above four Chinese medicine compatibility, drug effect strengthens mutually, thus the effect that the electuary of making has supplementing QI and nourishing YIN, blood circulation promoting and blood stasis dispelling, strengthening the spleen and stomach, braces up energy and delay senility, and it not only can be treated, simultaneously more can the prevention of arterial blood supply incomplete, angina pectoris, myocardial infarction, diseases such as coronary heart disease, hyperlipidemia, and can also treat climacteric syndrome, senile dementia.Through Attached Hospital of Shandong College of Traditional Chinese Medicine, the Shandong Prov. Hospital, hospital clinicals such as Jinan City institute of traditional Chinese medicine checking proof, this electuary reaches 35% to angina pectoris symptomes complice obvious effective rate, total effective rate reaches 92.5%, to hyperlipidemia symptomes complice obvious effective rate 43.3%, total effective rate 90%, blood fat reducing obvious effective rate 16.7%, total effective rate 70%; To climacteric syndrome symptomes complice obvious effective rate 43.3%, total effective rate 93.3%.

Following table has provided the embodiment of Yinweichengong instant powder, and numerical value is ratio of weight and number in the table.

The production method of Yinweichengong instant powder of the present invention can be specified by following examples, as produces a as above-mentioned embodiment 4 described Yinweichengong instant powders, and then step is as follows:

A, get 2 parts of Pollen Maydiss, soak after 2-6 hour in the water of room temperature, put into 1.5 parts of Folium Ginkgos, decoct twice jointly, boiled 1-3 hour for the first time, boiled 0.5-2.5 hour for the second time, collecting decoction also filters,

B, treat that the filtrate temperature reduces to room temperature, put into 0-4 ℃ environment cold preservation 2-12 hour, impurity such as natural gum are separated out, refilter, filtrate is condensed into 1.15-1.45g/cm ³The clear paste of (90-95 ℃),

C, get 0.8 part of Fructus Crataegi, it with content ethanol reflux, extract, secondary under 75-80 ℃ temperature of 60%, 1-4 hour for the first time, 0.5-3.5 hour for the second time, and filter decocting liquid respectively, behind the merging filtrate, place 0-4 ℃ environment cold preservation 2-12 hour, separate out to contamination precipitations such as pectin, refilter decocting liquid, be condensed into 1.15-1.45g/cm behind the filtrate recycling ethanol ³Clear paste,

D, above-mentioned b gained clear paste is mixed with above-mentioned c gained clear paste, must mix clear paste, in mixing clear paste, add Icing Sugar that mixes one times of clear paste weight and the dextrin that mixes one times of clear paste weight, add 0.004 part again, make granule with the dissolved vitamin E of small amount of ethanol.

It is as follows that the Yinweichengong instant powder of making is applied to Clinical results:

CHD group minimal ages 40 years old, maximum 73 years old age, 56.72 ± 4.7 years old mean age;

Hyperlipidemia group minimal ages 41 years old, maximum 78 years old age, 57.76 ± 5.1 years old mean age;

Climacteric syndrome group minimal ages 46 years old, maximum 53 years old age, 49 ± 1.2 years old mean age.

Yinweichengong instant powder is to the thoracic obstruction (angina pectoris) symptomes complice obvious effective rate 35%, total effective rate 92.5%; Angina pectoris obvious effective rate 35%, total effective rate 90%; To hyperlipidemia symptomes complice obvious effective rate 43.3%, total effective rate 90%; To climacteric syndrome symptomes complice obvious effective rate 43.3%, total effective rate 93.3%.

Claims

1, a kind of Yinweichengong instant powder, comprise Folium Ginkgo, Fructus Crataegi, vitamin E, it is characterized in that also comprising Pollen Maydis, and the ratio of weight and number of its used medicine components is: Fructus Crataegi: Folium Ginkgo: Pollen Maydis: vitamin E=1: 0.45-13.5: 0.7-16: 0.0005-0.05.

2, Yinweichengong instant powder according to claim 1 is characterized in that the ratio of weight and number of its used medicine components is:

Fructus Crataegi: Folium Ginkgo: Pollen Maydis: vitamin E=1: 0.786-5.25: 1.143-6.5: 0.00143-0.0175.

3, a kind of manufacture method of Yinweichengong instant powder is characterized in that may further comprise the steps:

A, by the weight fraction ratio of its used medicine components, it is standby to get 1 part of Fructus Crataegi, Folium Ginkgo 0.45-13.5 part, Pollen Maydis 0.7-16 part, vitamin E 0.0005-0.05 part,

B, get Pollen Maydis, after in excessive water, soaking, put into Folium Ginkgo, decoct, filter, the filtrate of impurity such as gummy, natural cooling,

4, the manufacture method of Yinweichengong instant powder according to claim 3 is characterized in that described in b Pollen Maydis soaks after 2-6 hour in the water of room temperature, put into the common decoction twice of Folium Ginkgo, boils 1-3 hour for the first time, boils 0.5-2.5 hour for the second time.

5, the manufacture method of Yinweichengong instant powder according to claim 3 is characterized in that described in c, is in 0-4 ℃ the environment cold preservation 2-12 hour in temperature.

6, the manufacture method of Yinweichengong instant powder according to claim 3 is characterized in that described in d, is ethanol reflux, extract, secondary under 75-80 ℃ temperature of 60% with content, 1-4 hour for the first time, and 0.5-3.5 hour for the second time.