CN1104502A - External-use medicine for gynecopathy - Google Patents
External-use medicine for gynecopathy Download PDFInfo
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- CN1104502A CN1104502A CN 93121386 CN93121386A CN1104502A CN 1104502 A CN1104502 A CN 1104502A CN 93121386 CN93121386 CN 93121386 CN 93121386 A CN93121386 A CN 93121386A CN 1104502 A CN1104502 A CN 1104502A
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- medicine
- gynecopathy
- percentage
- vagina
- lactic acid
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Abstract
The external-use medicine with both health-care and curative effect for gynecopathy comprises emulsified dimethyl silicon oil 0.5-80%, vitamine E 0.05-5%, glucose 0.1-10% (percentage on weight) lactic acid in proper quanitity and water. This medicine has lubricating effect, can accelerate normal bacilli in vagina growing as well as inhibiting pathogenic bacteria, strengthen the tissue repaire and injury-resisting ability of vaginal mucosa. It can be mainly used to cure vagina drying, itching and atrophic senile vaginitis caused by hypo-ovaria or other reason and coitus pain. The total effective rate is 87%.
Description
The present invention relates to a kind of associativity medicine, especially gynaecopathia is had the medicine of treatment and health care dual function.
Chinese patent application CN 1031024(application number 87105348) disclosing a kind of " Chinese herbal medicine diaper cream and preparation method thereof ", is the cosmetics that are used for baby buttocks, pudendum and thigh portion.Form by natural goods and prepared from traditional Chinese medicines, its prescription is: monoglyceride 16, lanoline 2, Cetyl Alcohol 3, spiny dogfish gastral cavity 1, methyl-silicone oil 0.5, Oleum Ricini 2, sodium lauryl sulphate 0.3-0.35,10% Fructus Kochiae extract 10-13.5,10% Radix Sanguisorbae extract 10-14,10% Rhizoma Tupistrae pachynemae extract 1.0-2.5,12% aloe extraction liquid 4-7, Radix Isatidis liquid 13-17,30% Fructus Xanthii alcohol water soak 8-10, essence 0.1-0.5,33% Radix Scrophulariae tincture 4-8, water adds to 100, be mainly used in the control diaper rash, treatment eczema, dermatitis, miliaria.
Chinese patent application CN 86107442A discloses a kind of " fresh milk nutritive frost and series of products and preparation technology ", its constituent content is (percentage by weight): fresh milk 20-30%, monoglyceride 6-8%, octadecanol 9-12%, stearic acid 4-6%, glycerol 15-20%, fatty acid sodium lauryl sulfate 4.5-5.6%, peregal SO-15 2.3-3.7%, dimethicone 2-4%, white oil 2-3%, ethyl hydroxybenzoate 0.3-0.4%, methyl hydroxybenzoate 0.2-0.3%, essence 0.5-0.7%, surplus is a water.
More than two applications all belong to series cosmetics, wherein all contain methyl-silicone oil, but the content of its methyl-silicone oil is all lower, in prescription is formed, work the usefulness that lubricates the skin and muscle auxiliaryly.
It is the external used medicine that is used for gynaecopathia of main effective ingredient with the emulsifying dimethicone that purpose of the present invention aims to provide a kind of.
External-use medicine for gynecopathy of the present invention mainly is grouped into (percentage by weight) by following one-tenth: emulsifying dimethicone 0.5-80%, vitamin E 0.05-5%, glucose 0.1-10%, lactic acid are an amount of, and surplus is a water.
In medicine of the present invention, emulsifying dimethicone (also claiming medical silicon cream) has specially good effect to chapped skin, but Glycerin is the main medicinal component of this medicine, its better weight range be 20-50%; Vitamin E can promote the cell growth, recover the cellular metabolism function, prevent cytolipin peroxidating and defying age, help promoting vaginal epithelial cell growth and functional rehabilitation, its better weight range be 0.1-2%, glucose also can directly utilize for lactobacillus except that supplying with vaginal epithelial cell nutrition; The effect of lactic acid is a pH value of regulating this medicine, and the concentration that is adopted is 5%-65%, and the pH value of regulating this medicine is between 3-6.This medicine is except that adding above composition, also can add emulsifying agent 0.5-15%, as naturally occurring emulsifying agent: natural gum (arabic gum, tragakanta, lucky natural gum etc.), agar, pectin, lanonol, lecithin etc., perhaps synthetic emulsifier: organic amine soap, sulfated fatty oil, sulfuric acid ester alcohols, azochlorosulfonate acid compound etc., make Emulsion.Add 5-30% fatty substrate such as oleum theobromatis, Oleum Linderae, Sapium sebiferum (L.) Roxb. fat, semi-synthetic Oleum Cocois, hydrogenated oils, perhaps 10-30% water solublity and hydrophilic matrix such as glycerin gelatine, Polyethylene Glycol, tween-61 etc. are made suppository.
Medicine of the present invention has lubricated and promotes vaginal mucosa reparation health care, the normal bacillus of promotion vagina to grow, suppress pathogenic bacteria growth, improve the anti-injury repairing ability of vaginal mucosa, cure mainly ovarian hypofunction and vagina drying, pruritus of vagina, dyspareunia due to the vagina drying pruritus, atrophic (senile) vaginitis and other reason that cause.This medicine is the auxotype medicine, does not contain hormone and antibiotics, have no side effect, but life-time service.Through clinical verification, to because of estrogen secretion deficiency, vagina drying, atrophy, sexual life difficulty person, symptom is obviously improved, and total effective rate is 87%.
Embodiment:
1, get medical silicon cream 350g, vitamin E 5g, glucose 20g, distilled water are made ointment 1000ml in right amount, wherein regulate PH with 20% lactic acid and reach 4.
2, get medical silicon cream 150g, vitamin E2 g, glucose 8g, emulsifying agent natural gum 25g, distilled water is made emulsifying agent 1000ml in right amount, wherein regulates PH to 5 with 15% lactic acid.
3, get medical silicon cream 600g, vitamin e1 0g, glucose 25g, oleum theobromatis (fatty substrate) 280g, distilled water is made suppository 1000g in right amount, and wherein regulating PH with 30% lactic acid is 3.5.
Claims (7)
1, a kind of external-use medicine for gynecopathy is characterized in that being grouped into (percentage by weight) by following one-tenth: emulsifying dimethicone 0.5-80%, vitamin E 0.05-5%, glucose 0.1-10%, lactic acid are an amount of, and surplus is a water.
2, according to the described external used medicine of claim 1, the percentage by weight that it is characterized in that described emulsifying dimethicone is 20-50%.
3, according to the described external used medicine of claim 1, the percentage by weight that it is characterized in that described vitamin E is 0.1-2%.
4, according to the described external used medicine of claim 1, it is characterized in that described lactic acid concn is 5-65%, regulate PH between 3-6.
5,, it is characterized in that also containing emulsifying agent 0.5-15% according to the described external used medicine of claim 1.
6,, it is characterized in that also containing fatty substrate 5-30% according to the described external used medicine of claim 1.
7,, it is characterized in that also containing water solublity and hydrophilic matrix 10-30% according to the described external used medicine of claim 1.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93121386A CN1039087C (en) | 1993-12-29 | 1993-12-29 | External-use medicine for gynecopathy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN93121386A CN1039087C (en) | 1993-12-29 | 1993-12-29 | External-use medicine for gynecopathy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1104502A true CN1104502A (en) | 1995-07-05 |
| CN1039087C CN1039087C (en) | 1998-07-15 |
Family
ID=4993690
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN93121386A Expired - Fee Related CN1039087C (en) | 1993-12-29 | 1993-12-29 | External-use medicine for gynecopathy |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1039087C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999026635A1 (en) * | 1997-11-24 | 1999-06-03 | Zhongming Zeng | Pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in vagina and the use thereof |
| WO2000002554A1 (en) * | 1998-07-10 | 2000-01-20 | Giorgio Panin | Vitamin e and esters thereof for use in the topical treatment of mucosal pathologies |
| US6964949B2 (en) | 2000-05-24 | 2005-11-15 | Shanghai Jiao Da Onlly Co., Ltd. | Pharmaceutical compositions for promoting the growth of gram-positive bacilli and increasing the acidity in the vagina and the use thereof |
| EP1776101A1 (en) * | 2004-06-17 | 2007-04-25 | Kimberley-Clark Worldwide, Inc. | Vaginal health products |
| CN100389763C (en) * | 2004-02-10 | 2008-05-28 | 周世兰 | Lactic acid , glycerin formulation for female vagina acidity, humidity improvement |
-
1993
- 1993-12-29 CN CN93121386A patent/CN1039087C/en not_active Expired - Fee Related
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999026635A1 (en) * | 1997-11-24 | 1999-06-03 | Zhongming Zeng | Pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in vagina and the use thereof |
| WO1999026636A1 (en) * | 1997-11-24 | 1999-06-03 | Zhongming Zeng | Pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in vagina and the use thereof |
| US6440949B1 (en) | 1997-11-24 | 2002-08-27 | Shanghai Jiao Da Onlly Co., Ltd. | Method for promoting the growth of gram-positive bacilli and increasing the acidity in vagina |
| US6632796B1 (en) | 1997-11-24 | 2003-10-14 | Shanghai Jiao Da Onlly Co., Ltd. | Pharmaceutical compositions for promoting the growth of gram-positive bacilli and increasing the acidity in vagina and the use thereof |
| WO2000002554A1 (en) * | 1998-07-10 | 2000-01-20 | Giorgio Panin | Vitamin e and esters thereof for use in the topical treatment of mucosal pathologies |
| US6964949B2 (en) | 2000-05-24 | 2005-11-15 | Shanghai Jiao Da Onlly Co., Ltd. | Pharmaceutical compositions for promoting the growth of gram-positive bacilli and increasing the acidity in the vagina and the use thereof |
| CN100389763C (en) * | 2004-02-10 | 2008-05-28 | 周世兰 | Lactic acid , glycerin formulation for female vagina acidity, humidity improvement |
| EP1776101A1 (en) * | 2004-06-17 | 2007-04-25 | Kimberley-Clark Worldwide, Inc. | Vaginal health products |
| EP1776101B1 (en) * | 2004-06-17 | 2016-11-16 | Kimberly-Clark Worldwide, Inc. | Vaginal health products |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1039087C (en) | 1998-07-15 |
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| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |