CN110418967A - 反应组件、样本分析仪及混合方法 - Google Patents
反应组件、样本分析仪及混合方法 Download PDFInfo
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- CN110418967A CN110418967A CN201780088089.3A CN201780088089A CN110418967A CN 110418967 A CN110418967 A CN 110418967A CN 201780088089 A CN201780088089 A CN 201780088089A CN 110418967 A CN110418967 A CN 110418967A
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- reagent
- sampler
- reaction tank
- reaction
- biological sample
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- 238000000034 method Methods 0.000 title claims description 41
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 209
- 239000012472 biological sample Substances 0.000 claims abstract description 115
- 239000007788 liquid Substances 0.000 claims description 71
- 239000000523 sample Substances 0.000 claims description 39
- 238000001514 detection method Methods 0.000 claims description 34
- 238000009991 scouring Methods 0.000 claims description 19
- 239000003219 hemolytic agent Substances 0.000 claims description 15
- 239000000975 dye Substances 0.000 claims description 12
- 239000012895 dilution Substances 0.000 claims description 8
- 238000010790 dilution Methods 0.000 claims description 8
- 230000008569 process Effects 0.000 claims description 6
- 230000008859 change Effects 0.000 claims description 3
- 239000011259 mixed solution Substances 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 description 29
- 210000004369 blood Anatomy 0.000 description 16
- 239000008280 blood Substances 0.000 description 16
- 230000000694 effects Effects 0.000 description 13
- 230000001133 acceleration Effects 0.000 description 11
- 210000003743 erythrocyte Anatomy 0.000 description 11
- 238000012360 testing method Methods 0.000 description 11
- 239000002245 particle Substances 0.000 description 10
- 210000003714 granulocyte Anatomy 0.000 description 7
- 238000004820 blood count Methods 0.000 description 6
- 210000003924 normoblast Anatomy 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 239000008187 granular material Substances 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- 206010018910 Haemolysis Diseases 0.000 description 3
- 102000001554 Hemoglobins Human genes 0.000 description 2
- 108010054147 Hemoglobins Proteins 0.000 description 2
- 210000001772 blood platelet Anatomy 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 230000008588 hemolysis Effects 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 230000002949 hemolytic effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000003447 ipsilateral effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000021715 photosynthesis, light harvesting Effects 0.000 description 1
- 230000036632 reaction speed Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1002—Reagent dispensers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1048—General features of the devices using the transfer device for another function
- G01N2035/1058—General features of the devices using the transfer device for another function for mixing
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
一种反应组件,包括采样器(10)和反应池(20),采样器(10)用于采集生物样本并将生物样本注入反应池(20)内,反应池(20)的池壁上设置有第一通孔(21),第一通孔(21)用于注入第一试剂,采样器(10)伸入反应池(20)后,第一通孔(21)的中心线C1错开采样器(10)设置。该反应组件混合溶液的混合度较高。
Description
PCT国内申请,说明书已公开。
Claims (28)
- PCT国内申请,权利要求书已公开。
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2017/091096 WO2019000392A1 (zh) | 2017-06-30 | 2017-06-30 | 反应组件、样本分析仪及混合方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN110418967A true CN110418967A (zh) | 2019-11-05 |
CN110418967B CN110418967B (zh) | 2024-02-06 |
Family
ID=64740789
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201780088089.3A Active CN110418967B (zh) | 2017-06-30 | 2017-06-30 | 反应组件、样本分析仪及混合方法 |
Country Status (3)
Country | Link |
---|---|
US (1) | US20200225257A1 (zh) |
CN (1) | CN110418967B (zh) |
WO (1) | WO2019000392A1 (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111024481A (zh) * | 2019-12-30 | 2020-04-17 | 深圳开立生物医疗科技股份有限公司 | 一种样本混匀方法及样本分析仪 |
CN114618419A (zh) * | 2020-12-11 | 2022-06-14 | 深圳市帝迈生物技术有限公司 | 一种样本加注方法、样本加注组件以及样本分析仪 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3764041A (en) * | 1970-10-26 | 1973-10-09 | Searle & Co | Microdispensing process and apparatus |
US4398544A (en) * | 1981-10-15 | 1983-08-16 | Becton Dickinson And Company | Single and multiple sample needle assembly with vein entry indicator |
CN1182393C (zh) * | 1997-10-28 | 2004-12-29 | Abx公司 | 血样按份额分配的方法和装置 |
US20050095724A1 (en) * | 2003-09-19 | 2005-05-05 | Kabushiki Kaisha Toshiba | Chemical analyzer, method for dispensing and dilution cup |
CN1643370A (zh) * | 2002-03-13 | 2005-07-20 | 松下电器产业株式会社 | 均化·反应完成的判定方法以及使用该方法的溶液浓度测定方法 |
CN1776410A (zh) * | 2005-11-30 | 2006-05-24 | 中国农业大学 | 一种乳粉蛋白质含量分析方法 |
US20120264646A1 (en) * | 2008-07-18 | 2012-10-18 | Raindance Technologies, Inc. | Enzyme quantification |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2357298A (en) * | 1942-09-25 | 1944-09-05 | Du Pont | Preparation of dialkyl peroxides |
ES2219643T3 (es) * | 1993-09-17 | 2004-12-01 | F. Hoffmann-La Roche Ag | Aparato analitico con un dispositivo para la suspension de particulas y procedimiento para llevar a cabo la suspension. |
WO2005090998A1 (ja) * | 2004-03-23 | 2005-09-29 | Matsushita Electric Industrial Co., Ltd. | 攪拌方法、セルおよびこれを用いた測定装置、測定方法 |
US20070078429A1 (en) * | 2005-06-15 | 2007-04-05 | Inviro Medical Devices Ltd. | Safety fluid transfer cannula |
CN102419375B (zh) * | 2011-08-24 | 2013-08-28 | 四川迈克生物科技股份有限公司 | 全自动化学发光免疫分析仪 |
JP6029971B2 (ja) * | 2012-12-21 | 2016-11-24 | シスメックス株式会社 | 検体分析装置およびピアサーの位置調整方法 |
EP2940477B1 (en) * | 2012-12-26 | 2019-02-20 | Hitachi High-Technologies Corporation | Automatic analyzer |
CN109406801A (zh) * | 2014-07-01 | 2019-03-01 | 深圳迈瑞生物医疗电子股份有限公司 | 样本分析仪及其样本采集和分配方法 |
CN105572400A (zh) * | 2015-11-06 | 2016-05-11 | 扬州大晟药用玻璃有限公司 | 一种样本反应容器及样本检测方法 |
-
2017
- 2017-06-30 WO PCT/CN2017/091096 patent/WO2019000392A1/zh active Application Filing
- 2017-06-30 CN CN201780088089.3A patent/CN110418967B/zh active Active
-
2019
- 2019-12-26 US US16/727,810 patent/US20200225257A1/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3764041A (en) * | 1970-10-26 | 1973-10-09 | Searle & Co | Microdispensing process and apparatus |
US4398544A (en) * | 1981-10-15 | 1983-08-16 | Becton Dickinson And Company | Single and multiple sample needle assembly with vein entry indicator |
CN1182393C (zh) * | 1997-10-28 | 2004-12-29 | Abx公司 | 血样按份额分配的方法和装置 |
CN1643370A (zh) * | 2002-03-13 | 2005-07-20 | 松下电器产业株式会社 | 均化·反应完成的判定方法以及使用该方法的溶液浓度测定方法 |
US20050095724A1 (en) * | 2003-09-19 | 2005-05-05 | Kabushiki Kaisha Toshiba | Chemical analyzer, method for dispensing and dilution cup |
CN1776410A (zh) * | 2005-11-30 | 2006-05-24 | 中国农业大学 | 一种乳粉蛋白质含量分析方法 |
US20120264646A1 (en) * | 2008-07-18 | 2012-10-18 | Raindance Technologies, Inc. | Enzyme quantification |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111024481A (zh) * | 2019-12-30 | 2020-04-17 | 深圳开立生物医疗科技股份有限公司 | 一种样本混匀方法及样本分析仪 |
CN114618419A (zh) * | 2020-12-11 | 2022-06-14 | 深圳市帝迈生物技术有限公司 | 一种样本加注方法、样本加注组件以及样本分析仪 |
Also Published As
Publication number | Publication date |
---|---|
WO2019000392A1 (zh) | 2019-01-03 |
US20200225257A1 (en) | 2020-07-16 |
CN110418967B (zh) | 2024-02-06 |
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