CN110384234A - A kind of raising spacefarer body function compound formulation - Google Patents

A kind of raising spacefarer body function compound formulation Download PDF

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Publication number
CN110384234A
CN110384234A CN201910006301.8A CN201910006301A CN110384234A CN 110384234 A CN110384234 A CN 110384234A CN 201910006301 A CN201910006301 A CN 201910006301A CN 110384234 A CN110384234 A CN 110384234A
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spacefarer
powder
phosphatidylserine
raising
body function
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王基光
宋志勇
贺春月
张金凤
陈军静
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Aerospace Technology Co Ltd
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Aerospace Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A23L33/25—Synthetic polymers, e.g. vinylic or acrylic polymers
    • A23L33/26—Polyol polyesters, e.g. sucrose polyesters; Synthetic sugar polymers, e.g. polydextrose
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The present invention relates to a kind of raising spacefarer body function compound formulation, said preparation is made of following raw materials according: soybean lecithin, phosphatidylserine, 4-Aminobutanoicacid, Valerian root P.E, black fruit fructus lycii, seabuckthorn fruit powder, oat-beta glucan, vegetable fat powder, maltodextrin.Spacefarer's body function can be improved in preparation provided by the invention, and spacefarer is made more smoothly to complete aerial mission.In addition, this preparation also has anti-aging, the effect of beautifying face and moistering lotion.

Description

A kind of raising spacefarer body function compound formulation
Technical field
The present invention relates to a kind of pharmaceutical formulation, in particular to a series of changes occur for body during a kind of flight for spacefarer The pharmaceutical formulation of change and process flow.
Background technique
Numerous studies report that under weightlessness, a series of adaptability will occur for heart, blood vessel and its neural modulation system Variation, and then cause cardiovascular function low.Under state of weightlessness, body body fluid is shifted to head, increases thoracic cavity and head blood volume Add, urine volume increases, hypovolemia；Increased heart rate simultaneously, heart are often won output quantity and are reduced, especially the flight of experience long term space Afterwards, cardiac ejection fraction and ejection time percentage reduce, and left room is shunk last volume and increased, decreased cardiac function.Weightlessness may be used also To cause animal cardiovascalar system to will appear organic variation: such as myocardial atrophy, locular wall is thinning, aortic smooth amyotrophia and pipe Chamber, which becomes larger, waits pathological changes, and long-term space travel, can lead to lower limb antigravity muscle (such as thigh quadriceps muscle of thigh in astronaut's process Deng) there is apparent atrophic variation；Weightlessness can cause bone amount quickly to be lost.Studies have reported that spacefarer's ridge after space flight The bone mineral density (BMD) of vertebra, femur and pelvis monthly reduces by 1.0 %-1.6 %.Under the space environment in 4- June, ridge Column entirety bone bulk-forming (v) BMD is reduced with the speed of monthly 0.9 %, and cancellous bone vBMD monthly reduces by 0.9 %, and hip Monthly Loss Rate is respectively 1.2 % -1.5 %, 0.4 %-0.5 % and 2.2 to the vBMD of whole, cortex bone and cancellous bone %-2.7 %；Weightlessness can also lead to the ill symptoms such as astronaut's endocrine disorder, immunologic hypofunction, gastrointestinal disorder.For space flight Member can be healthy and smoothly completes aerial mission, it is necessary to research and develop a kind of pharmaceutical formulation that can be improved spacefarer's body function.
Summary of the invention
The purpose of the present invention is improving spacefarer's body function in all its bearings, aerial mission is smoothly completed.
In order to complete the purpose of the present invention, a kind of raising spacefarer body function compound formulation is made of following raw material: big Fabaceous Lecithin, phosphatidylserine, 4-Aminobutanoicacid, Valerian root P.E, black fruit fructus lycii, seabuckthorn fruit powder, avenabeta glucosan plant rouge End, maltodextrin.The component raw material weight ratio of said preparation is as follows:
Soybean lecithin 20%-30%
Phosphatidylserine 15%-18%
4-Aminobutanoicacid 15%-18%
Valerian root P.E 10%-15%
Black fruit fructus lycii 10%-12%
Seabuckthorn fruit powder 8%-10%
Avenabeta glucosan 5%-10%
Vegetable fat powder 2%-5%
Maltodextrin 1%-2%
Specific production technology is as follows:
By soybean lecithin, phosphatidylserine, 4-Aminobutanoicacid, Valerian root P.E, black fruit fructus lycii, seabuckthorn fruit powder, oat β-Portugal gathers Sugar, vegetable fat powder, maltodextrin are pulverized and mixed uniformly, cross 80 meshes, control environment temperature and humidity, and certain specification is dressed up in drying Pulvis.
A kind of raising spacefarer body function compound formulation provided by the invention, the effect of main component soybean lecithin is: Soybean lecithin is the essence substance extracted from soybean.It is also one of the lipid component that human body needs.
1, it delays senescence
The cell for constituting human body has 60,000,000 hundred million.1 second will be 500,000 dead, while regenerating 500,000.With the increasing at age Long, the quantity of cell death will be more and more, and regenerated cell is fewer and fewer.When cell death number is greater than regeneration number, People begins to aging.The metabolic processes of cell are regulated and controled by cell membrane, the health degree of cell membrane, direct relation To the self-repairing capability of cell, information transfer capacity, the ability for resisting external aggression, cell activity and power of regeneration etc..Carefully After birth is mainly to be made of lecithin, supplements lecithin to human body, it is meant that can repair the cell membrane being damaged, improve Cell membrane function makes cell membrane softening and rejuvenation, increases cell activity.Pass through the intake to lecithin, so that it may improve people Metabolic capability, the power of regeneration of self-healing ability and antibody tissue of body, enhance the vitality of human body, fundamentally delaying human body Aging.
2, blood vessel scavenger, prevention cardiovascular and cerebrovascular disease
Lecithin can emulsify, cut grease, and can make by the cholesterol being attached on vascular wall and fat emulsification at particulate Be dissolved in blood and transport liver back and be metabolized.Play the role of softening blood vessel, improve serum lipids, removes peroxide, make Blood Cholesterol and fat content reduce, to reduce blood viscosity, promote blood circulation, reduce fat in the blood vessels Residence time.In turn, the blood for making full of nutrition, oxygen-containing abundance, flows to the organs such as brain, heart unblockedly.Japan's celebrating It answers University Medical College food nutrition system once to do clinical trial, and concludes that by taking lecithin, can be effectively reduced High blood lipid and cholesterol, and then the diseases such as prevention and treatment of coronary heart disease, hypertension, myocardial infarction, cerebral thrombosis, cerebral hemorrhage, artery sclerosis.
3, brain tonic and intelligence development, prevention senile dementia
Lecithin can provide sufficient nutriment for brain nervous cell, accelerate the information transmission speed between cranial nerve, thus Brain activity is improved, brain fag is eliminated, keeps human thinking quick, improves study and work efficiency.Lecithin is impaired in reparation While hurting brain cell, get through obstacle between brain and blood circulation, the normal function of cranial nerve cell can be maintained, and is enhanced big Cerebral nervous system function, and then reach the effect of preventing senile dementia.
4, the patron saint of liver
Heavy drinking or overnutrition can aggravate the burden of liver cell, reduce the ability of liver synthetic phospholipid.When phosphorus in human body Rouge lack of choline will lead to a large amount of accumulations of the fat in liver, form fatty liver, be destroyed liver cell, liver function subtracts It moves back, causes cirrhosis even liver cancer.Science proves: liver cell metabolism can be enhanced by mending food lecithin, promoted fat acid decomposition, protected Protect liver is dirty, the generation of the illnesss such as prevention fatty liver.
5, the nutriment of diabetes patient
Lecithin can enhance pancreatic functions, repair Stem Cells, and the insulin for keeping its secretion sufficient reduces blood glucose, effectively will Glucose transport in blood is into cell, to mitigate diabetic condition.
6, the main component for constituting biomembrane, is the indispensable base substance of human body
Lecithin can promote spirit to pass to, and improve brain activity, and due to can effectively prevent gallbladder with good emulsibility Sterol precipitates in vascular wall and removes partly precipitated object, so that playing reduces serum cholesterol, reduce blood viscosity, promote blood Circulation, prevents the effect of cardiovascular disease.Therefore the product for often eating the soft phosphatide containing soybean, can effectively adjust blood lipid and gallbladder Sterol improves cerebral function, improves memory, prevents and treats fatty liver etc..
The effect of main component phosphatidylserine:
Phosphatidylserine (PS), one big emerging " intelligent nutrition element " being known as after choline and " docosapentaenoic acid " DHA. Expert thinks that this natural materials can help cell wall to keep flexibility, and can enhance the nerve of transmission brain signal The efficiency of mediator helps brain high-efficiency operation, excites the state of activation of brain.Specifically, phosphatidylserine has following function Energy.
1, cerebral function is improved, is focused on, memory is improved
America and Europe emerges largely that (meta-analysis refers to the multiple independences done to some problem to the meta-analysis of phosphatidylserine Result of study carries out quantitatively or qualitatively integrating for system), main purpose is by the more objective ground heddle of previous result of study Conjunction reflects.Someone analyzes 9 double blinds, placebo, the clinical test that totally 1224 patients participate in, the results show that After supplementing phosphatidylserine, the parameter about cognition and memory significantly improves.Unquestionably, phosphatidylserine is supplemented Long-term memory, long-term cognition and free talk and logicality speech ability can be improved.With advancing age, phosphatidyl silk Propylhomoserin and other important intracerebral chemical substances can gradually decrease, and weaken so as to cause memory, cognitive power.Supplement phosphatidyl silk Propylhomoserin can increase brain bur number, the mobility of brain cell membrane and promote glucose metabolism in brain cell, to make brain cell more It is active, promote attention to concentrate, stepping up vigilance property and memory.Italy, the Scandinavian Peninsula and European other countries Phosphatidylserine replenishers are widely applied all to treat the cognitive disorder disease of aging initiation and old memory loss.
2, student performance is improved
Once someone specially tested the effect that phosphatidylserine alleviates stress, and test uses double blind, placebo, Continuous 30 days, 300 milligrams of phosphatidylserines of Health College Students are given once daily.University student must complete to have within given time The mathematics test of certain difficulty, and record them and face the reaction of pressure.As a result, it has been found that the student using phosphatidylserine exists Reagency, confidence and performance aspect are better than control group, their achievements in examination are also more preferable.One research is directed to 120 The research of Chongqing SiChuan middle school Senior student also found, take the student for strengthening phosphatidylserine, after 40 days, The memory of language and non-language is all significantly increased.
3, it relieves stress, promotes recovery, the balance mood of brain fag
Multiple studies have shown that the level of stress hormone excessive in phosphatidylserine can significantly reduce work strain person's body, subtracts Light pressure alleviates brain fatigue;Phosphatidylserine, which may also act to big intracerebral, influences the neurotransmitter levels of mood, can promote Into attention concentration, stepping up vigilance property and memory, improper release mood (such as depressed, dejected) is helped.
4, it helps to repair brain damage
Phosphatidylserine is one of main component of brain neuroblastoma, can nutrition and activation brain in various enzymes activity, can delay The reduction process of neurotransmitter helps to repair, updates brain damaged cell and remove harmful substance.It can make the elderly's Memory is restored to the level before 14 years, and after studies have shown that edible phospholipid acyl serine 12 weeks, 66 years old people has 52 years old people Memory.
In addition to this, phosphatidylserine and DHA can mutually promote absorption, play a protective role to 2 A cells of nerve .Phosphatidylserine abundant can increase the mobility of cell membrane, promote the development of intelligence.Phosphatidylserine and DHA mono- It rises and can protect central nervous system, promote fetal intelligence development.
Studies have shown why phosphatidylserine can enhance the intelligence of people, main reason is that it can wear rapidly Blood-brain barrier is crossed, into brain.Play the role of cerebral capillary smooth muscle cell of releiving in brain, increases brain blood supply. So there is many products in terms of cerebral apoplexy all using PS as raw material in recent years.
The effect of main component 4-Aminobutanoicacid:
4-Aminobutanoicacid is inhibitory neurotransmitter critically important in central nervous system, it is a kind of naturally occurring non-protein Amino acid is formed, there is extremely important physiological function, it can promote the reactivity of brain, brain tonic and intelligence development, and anti-epileptic promotes to sleep It sleeps, beauty moisturizing delays brain aging function, can supplement human body inhibitory neurotransmitter, has good blood pressure reduction effect.Promote Kidney Fitness improvement and protective effect.Inhibit fatty liver and obesity, activates liver function.The micro 4-Aminobutanoicacid of daily iron supplement has Conducive to the alleviation of heart and brain blood pressure, and the balance of amino acid metabolism in human body can be promoted, adjust immune function.
4-Aminobutanoicacid belongs to strong neural inhibitory aminoacid, has calmness, hypnosis, anticonvulsion, blood pressure lowering physiological action. It is inhibitory neurotransmitter (Inhibitory Neurotransmitter), can inhibit the activity of animal, reduce energy Consumption.Aminobutyric acid acts on the GABA receptor in zooblast, and GABA receptor is a chloride channel, the inhibition of GABA Or excitability is to rely on the chlorine ion concentration inside and outside cell membrane, after GABA receptor is activated, causes chloride channel open, Cell membrane be can increase to chloride ion permeability, chloride ion is flowed into nerve cell, cause cell membrane hyperpolarization, inhibit nerve thin Cell element excitement, to reduce the amount of exercise of animal.
It is the unintentional motion by reducing animal, to reduce energy consumption, to reach somatotrophic purpose.γ- Aminobutyric acid can promote the secretion of animal gastric juice and growth hormone, to improve the speed of growth and feed intake;The excited animal of energy Feeding maincenter, to increase feed intake.
The effect of main component Valerian root P.E:
1. angst resistance effect: the experiment proves that both the main component valerenic acid of Valerian root P.E and valerienol can be reinforced The reaction of γ-aminobutyric acid (GABA) receptor.Experiment discovery administration group (valerenic acid and valerienol) rat blood serum cortisone Level is significantly reduced, and all shows that valerian has apparent angst resistance effect.
2. antidepressant effect: valerian has the function of depressive state behavior different degrees of.Valerian is green non-poisonous secondary work Calm, hypnosis and anticonvulsion is at home and abroad widely used in sleeping substance.Can allow in human feelings thread becomes mild.
3. promoting blood circulation and blood tonification effect: valerian is sweet in flavor, and master enters the heart channel of Hang-Shaoyin, has effects that mental-tranquilization.Had no peace of mind with controlling, usually With semen ziziphi spinosae, etc. sleepings plant with use；If the insufficiency of heart and spleen, can the invigorating QI and bloods such as compatibility Radix Angelicae Sinensis, Radix Astragali, Radix Codonopsis, arillus longan medicine.
4. research discovery valerian has treatment blood stasis, traumatic injury.Effect has alleviation epigastric pain in fact, and wound goes out Blood and the effects of grinding external application.
The effect of main component black fruit fructus lycii:
1, lycium ruthenicum can with blood-enriching tranquillizing, improve sleep, and can prevent wrinkle of skin ahead of time generate, be current nature most Effective antioxidant.It can not only prevent generating ahead of time for wrinkle of skin, more can supplement the nutrients and eliminate and is harmful in vivo Free radical.
2, the anthocyanidin in lycium ruthenicum is natural sunlight overcover, can prevent injury of the ultraviolet light to skin.
3, lycium ruthenicum has the function of apparent reducing blood lipid, adjusts lipid metabolism, has to prevention cardiovascular disease and actively makees With.Lycium ruthenicum have it is hypoglycemic, the activity of superoxide dismutase in damaged islet cells can be remarkably reinforced in lycium ruthenicum polysaccharide, mention The oxidation resistance of high islet cells mitigates damage of the peroxide to cell, reduces malonaldehyde production quantity, therefore lycium ruthenicum is more Sugar has certain protective effect to islet cells.
4, lycium ruthenicum is natural benefit nickel product.Chromium, nickel are also all microelements necessary to human body, but content is compared with Gao Shihui Intoxicating phenomenon is generated, chromium has close pass with metabolism sugared in human body, the metabolism of lipid, the synthesis of protein, nucleic acid metabolism etc. System.The content of chromium is lower than content in normal milk (5~15ug/ml) in black fruit fructus lycii, will not generate intoxicating phenomenon to human body.Nickel In human body as bio-ligand co-factor, promote the ferric absorption of enteral, the content of nickel is than cereal butcher's meat vegetable in black fruit fructus lycii Wanting in dish (0.1~0.3 μ g/g) is high, but the concentration range will not constitute human body to poison and threaten, therefore black fruit fructus lycii is again With the benefit nickel agent drug effect as pure sense.Lead, cadmium are all the vertical distributions of environmental organization strict control, right Human body is harmful and unhelpful, and the content (0.5~3.0 μ g/g) in lycium ruthenicum in the more general plant of lead, cadmium content is much lower.
5, lycium ruthenicum is natural benefit cobalt agent.Cobalt with low toxicity and participates in vitamin B12 composition and stimulates hematopoiesis to human body It acts on, the content of cobalt in black fruit fructus lycii, much higher than 0.2~0.6ppm of content (dry weight) of green vegetable, but the concentration range is still Human body will not be constituted to poison and threatened, black fruit fructus lycii has the function of the benefit cobalt agent drug as pure sense.
6, lycium ruthenicum has effects that anti-cancer and cancer-preventing.Lycium ruthenicum ingredient most outstanding is anthocyanidin, and anthocyanidin is good Color pigments, even more a kind of potent antioxidant can prevent presenility, enhance blood vessel elasticity, inhibited allergy and inflammation, changed Kind joint flexibility.Cancer is also caused by damaging inhereditary material (DNA) because of free radical.By conservation genetics substance, cyanine Element indirectly will protect us to anticancer.Although long-term, anthocyanidin truly has indirect protective effect.And cyanine Element removes the effect of free radical, also cancer cell can be allowed to can not be successfully diffusion, and the cell of the more health of protection is from thin by cancer whereby Born of the same parents are corroded.On the other hand some cancers form tumour through the substance of dissolution tissue and cell, these cancer cells generate dissolution Enzyme With albumen Enzyme, and anthocyanidin energy protected protein matter is not influenced by albumen Enzyme.
Black fruit fructus lycii is containing a certain amount of essential fatty acid and 8 kinds of amino acid needed by human, and there are also a certain amount of Vc. Most significant is that it contains more reduced sugar and pigment, pigment be black fruit matrimony vine oxidation resistant and the activity to delay senescence at Point, to play the role of anti-aging, there is far-reaching potentiality to be exploited.
The effect of main component seabuckthorn fruit powder:
Sea buckthorn fruit is sour-sweet, protein rich in, in more than the 20 kinds of amino acid contained by it, including 8 kinds of ammonia needed by human Base acid.Ascorbic content is 3 times, 20 times of hawthorn, 100 times of apple of Chinese gooseberry.The content for tieing up raw yarn E is beans 30 times of oil.The content of vitamin B1 is 2 times of strawberry;Other also contain vitamin B2, citrin, folic acid, leaf amide and Microelement and unsaturated fatty acid.Serotonin in fructus hippophae.There is significant anti-tumor activity to act on,
Often drink sea-buckthorn tea has relaxation effect to ischemic heart disease, coronary heart diseases and angina pectoris, reduces blood cholesterol triglyceride, Myocardial blood supply state can preferably be improved;It is effective to various inflammation, it is obvious such as the effects of sphagitis, tonsillitis, prostatitis; With bile secretion is promoted, enhance the effect of capillary function.Clinical test proves that sea-buckthorn tea can treat constipation.Due to coffee Alkali content is low, can reduce central nervous excitation, drinks suitable for old man, hypertensive patient and its neurasthenic people.
The effect of main component avenabeta glucosan:
Beta glucan in blood glucose level, hormone response, vitamin and minerals biological effect have certain adjusting Effect, has positive effect to preventing colon cancer.Beta glucan is low-calorie diet, not easily digested after eating, can Slow down the increase of Glucose in Blood by Cyclic, prevention and obesity controlling disease, diabetes and cardiovascular disease.Again due to beta glucan Have the property of water swelling, after people is edible can water swelling under one's belt, generate satiety, prevent hyperalimentation.In addition it is in intestines It is interior to promote intestinal motility, there is osmosis in colon, prevent constipation, shorten time of the waste by enteron aisle, reduces Pollution of the enteral carcinogenic substance to intestinal tube, reaches protective effect on cancer risk.In oral cavity, beta glucan cannot be generated the bacterium point of saprodontia Solution produces acid and corrodes enamel, has the function of anti-caries.
Avenabeta glucosan has critically important physiology function to human health as a kind of soluble high-quality dietary fiber Can, and largely studied and true confirmed with epidemiological survey result both at home and abroad.
Serum cholesterol is reduced, cardiovascular disease is prevented
Avenabeta glucosan can reduce human body stomach and absorb fatty mollic acid, reduce internal cholesterol biosynthesis, it was confirmed that β-Portugal is poly- Sugar has good serum cholesterol-lowering, prevents the function of cardiovascular disease.
Blood glucose level is adjusted, diabetes are prevented
Avenabeta glucosan can improve blood flow performance, accelerate carbohydrate during being absorbed and utilized by reducing lipids contents Transport speed and efficiency, while the hepatic and renal tissue lesion concurrent to diabetes has good repair, can effectively drop The decomposition of low hepatic glycogen, so as to cause blood glucose reduction.
Promote proliferation of intestinal probiotics, prevents intestinal cancer
Avenabeta glucosan can promote Bifidobacterium and Bacillus acidi lactici proliferation in mouse intestinal and excrement, and inhibit large intestine bar Bacterium breeding, improves intestinal environment, has the function of prebiotics；In addition beta glucan can also increase intestines peristalsis, and it is logical to shorten excrement The time of large intestine is spent, increases excrement amount and defecation frequency, reduces the time of contact of noxious material and intestinal wall, reduce theirs Toxic action.
Adjust body's immunity
Beta glucan as a kind of nonspecific immunomodulator, it can not only activate T, bone-marrow-derived lymphocyte, macrophage, from The immunocytes such as Natural killer cell, moreover it is possible to promote cell factor to generate, activating complement system promotes antibody to generate, to siberian crabapple System plays various adjustment effects.
The present invention is by soybean lecithin, phosphatidylserine, 4-Aminobutanoicacid, Valerian root P.E, black fruit fructus lycii, seabuckthorn fruit powder, Avenabeta glucosan, vegetable fat powder, maltodextrin adequately combine, and mutually cooperate with, the body function of spacefarer not only can be improved, Also there is anti-aging, the effect of beautifying face and moistering lotion.
Specific embodiment
Case study on implementation one
Soybean lecithin 25%, phosphatidylserine 17%, 4-Aminobutanoicacid 16%, Valerian root P.E 13%, 11 seabuckthorn fruit powder of black fruit fructus lycii 8%, avenabeta glucosan 6%, vegetable fat powder 3%, maltodextrin 1%
Specific production technology is as follows:
By soybean lecithin, phosphatidylserine, 4-Aminobutanoicacid, Valerian root P.E, black fruit fructus lycii, seabuckthorn fruit powder, oat β-Portugal gathers Sugar, vegetable fat powder, maltodextrin are pulverized and mixed uniformly, cross 80 meshes, and control environment temperature is lower than 30 DEG C, and humidity is lower than 50%, 60 DEG C Drying, dresses up the pulvis of certain specification.
Case study on implementation two:
Soybean lecithin 28%, phosphatidylserine 16%, 4-Aminobutanoicacid 16%, Valerian root P.E 11%, black fruit fructus lycii 11%, sea-buckthorn Powder 8%, avenabeta glucosan 6%, vegetable fat powder 3%, maltodextrin 1%
Specific production technology is as follows:
By soybean lecithin, phosphatidylserine, 4-Aminobutanoicacid, Valerian root P.E, black fruit fructus lycii, seabuckthorn fruit powder, oat β-Portugal gathers Sugar, vegetable fat powder, maltodextrin are pulverized and mixed uniformly, cross 80 meshes, and control environment temperature is lower than 30 DEG C, and humidity is lower than 50%, 60 DEG C Drying, dresses up the pulvis of certain specification.
Case study on implementation three:
Soybean lecithin 24%, phosphatidylserine 18%, 4-Aminobutanoicacid 17%, Valerian root P.E 12%, black fruit fructus lycii 11%, sea-buckthorn Powder 8%, avenabeta glucosan 6%, vegetable fat powder 3%, maltodextrin 1%
Specific production technology is as follows:
By soybean lecithin, phosphatidylserine, 4-Aminobutanoicacid, Valerian root P.E, black fruit fructus lycii, seabuckthorn fruit powder, oat β-Portugal gathers Sugar, vegetable fat powder, maltodextrin are pulverized and mixed uniformly, cross 80 meshes, and control environment temperature is lower than 30 DEG C, and humidity is lower than 50%, 60 DEG C Drying, dresses up the pulvis of certain specification.
It is tested with said preparation:
Experiment one:
Experiment purpose: repair of this preparation to memory is studied.
Experimental method: two groups of healthy rats on inspection are looked for, two groups of rats are divided into ground group and hang tail group, two groups of rats The multiple excessively same labyrinth before treatment records the time.Start to test later.Two groups of rats feed same food daily, Two groups of rats cross this labyrinth respectively after one month, and the rat used time for hanging tail group is significantly more than ground group.Hung tail daily later Group feeds this preparation, a month laggard walking maze experiment by multiple.It was found that the rat used time for hanging tail group has been restored to for the first time Walk the time in labyrinth.
Experimental result: preparation of the invention has restitution to memory.
Experiment two:
Experiment purpose: influence of this preparation to cerebral blood flow velocity, brain resistance is studied.
Experimental method: three groups of rats are respectively ground group, hang tail group (not feeding this preparation), hang tail feed group (feed sheet Preparation), cerebral blood flow velocity, vascular pressure and the brain drag data of three groups of rats of record before testing.Experiment 15 days, during which at any time Monitor and record the cerebral blood flow velocity, vascular pressure and brain resistance of three groups of rats.Ground group is unchanged.Hang tail group blood flow velocity Slow down, cerebral vascular resistance becomes larger.It hangs tail feed group initial stage blood flow velocity to slow down, cerebral vascular resistance becomes larger, and slowly restores two days later.
Experimental result: invention formulation can promote cerebral blood flow velocity, change brain resistance.
Experiment three:
Experiment purpose: influence of this preparation to bone density is studied.
Test method: 2 monthly age male Wistar rats are randomly divided into 3 groups by weight: blank group, model group, feed group. Feed group whole process gives this preparation, begins from the 2nd week, model group and feed group are with tail-suspension simulated weightlessness 3 weeks.4th weekend After rat is condemned to death, the B3D of its 7 different parts bones is measured respectively, wherein cranium and second dorsal vertebra Measure by buoyancy method, the Four lumbar vertebraes, humerus, femur, radioulna and shin bone are measured with Dual-energy X-rays absorptionmetry.
Compared to the blank group, model group cranium BMD is dramatically increased (p < 0.05) test result, thoracic vertebrae, radioulna, humerus Unchanged (p>0.05), lumbar vertebrae, femur, shin bone BMD are remarkably decreased (p<0.05, p<0.01) 1 compared with model group, feed group Lumbar vertebrae, femur, humerus BMD are significantly improved (p < 0.05, p < 0.01), while shin bone BMD is improved trend, and cranium, radioulnar Bone, thoracic vertebrae are unchanged (p > 0.05).
Experimental result: 3 weeks tails hang simulated weightlessness rat body BMD variation and particular tendency are presented, and head BMD is improved, upper limb And second dorsal vertebra BMD is remained unchanged；4th abdomen vertebra and hind leg BMD decline;Invention formulation is to the weightless osteoporosis of alleviation, correction The redistribution of weightlessness bone calcium has positive effect.

Claims (5)

1. a kind of raising spacefarer body function compound formulation, it is characterised in that: be with soybean lecithin, phosphatidylserine, 4- Aminobutyric acid, Valerian root P.E, black fruit fructus lycii, seabuckthorn fruit powder, avenabeta glucosan, vegetable fat powder, maltodextrin are made of supplementary material Oral powder.
2. a kind of raising spacefarer body function compound formulation according to claim 1, it is characterised in that: the component of said preparation is former Expect that weight ratio is as follows:
Soybean lecithin 25%, phosphatidylserine 17%, 4-Aminobutanoicacid 16%, Valerian root P.E 13%, 11 seabuckthorn fruit powder of black fruit fructus lycii 8%, avenabeta glucosan 6%, vegetable fat powder 3%, maltodextrin 1%.
3. a kind of raising spacefarer body function compound formulation according to claim 1, it is characterised in that: the component of said preparation is former Expect that weight ratio is as follows:
Soybean lecithin 28%, phosphatidylserine 16%, 4-Aminobutanoicacid 16%, Valerian root P.E 11%, black fruit fructus lycii 11%, sea-buckthorn Powder 8%, avenabeta glucosan 6%, vegetable fat powder 3%, maltodextrin 1%.
4. a kind of raising spacefarer body function compound formulation according to claim 1, it is characterised in that: the component of said preparation is former Expect that weight ratio is as follows:
Soybean lecithin 24%, phosphatidylserine 18%, 4-Aminobutanoicacid 17%, Valerian root P.E 12%, black fruit fructus lycii 11%, sea-buckthorn Powder 8%, avenabeta glucosan 6%, vegetable fat powder 3%, maltodextrin 1%.
5. a kind of raising spacefarer body function compound formulation according to claim 1, it is characterised in that: concrete technology flow process:
By soybean lecithin, phosphatidylserine, 4-Aminobutanoicacid, Valerian root P.E, black fruit fructus lycii, seabuckthorn fruit powder, oat β-Portugal gathers Sugar, vegetable fat powder, maltodextrin are pulverized and mixed uniformly, cross 80 meshes, and control environment temperature is lower than 30 DEG C, and humidity is lower than 50%, 60 DEG C Drying, dresses up the pulvis of certain specification.
CN201910006301.8A 2019-01-04 2019-01-04 A kind of raising spacefarer body function compound formulation Withdrawn CN110384234A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111296855A (en) * 2020-03-18 2020-06-19 西咸新区优恩生物科技股份有限公司 Targeting gene polypeptide nutrient for supplementing and improving physique of astronauts

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111296855A (en) * 2020-03-18 2020-06-19 西咸新区优恩生物科技股份有限公司 Targeting gene polypeptide nutrient for supplementing and improving physique of astronauts

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