CN110367367A - A kind of pressed candy and preparation method thereof making one deep sleep - Google Patents

A kind of pressed candy and preparation method thereof making one deep sleep Download PDF

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CN110367367A
CN110367367A CN201910788470.1A CN201910788470A CN110367367A CN 110367367 A CN110367367 A CN 110367367A CN 201910788470 A CN201910788470 A CN 201910788470A CN 110367367 A CN110367367 A CN 110367367A
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powder
royal jelly
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deep sleep
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刘玉华
张瑞玲
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    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/48Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
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    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G2220/00Products with special structure
    • A23G2220/20Products with special structure with a composite structure, e.g. laminated products, coated products, microstructures, e.g. with encapsulated ingredients
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The present invention relates to a kind of pressed candies and preparation method thereof for making one deep sleep, be made including the following raw material: powder, royal jelly freeze-dried powder, jujube concentration powder, γ-aminobutyric acid, ginsenoside powder and auxiliary material is concentrated in semen ziziphi spinosae, pressed candy of the present invention is adjusted body system by the synergistic effect of each raw material, be conducive to the metabolism of cardiovascular and cerebrovascular, required nutrition is sufficiently fed, and mainly passes through royal jelly freeze-dried powder and γ-aminobutyric acid collective effect;The royal jelly freeze-dried powder prepared by the method for the invention can promote the generation of sex hormone, promote to enter deep sleep in the human brain short time, its hetero-organization also can comprehensively adjust the physiological function of each organ of body, taking for short time can make human body sex hormone level between the physiology phase that sex hormone declines tend to be steady, and reduce involutional abnormal phenomenon.

Description

A kind of pressed candy and preparation method thereof making one deep sleep
Technical field
The invention belongs to health product technology fields, and in particular to a kind of pressed candy for making one deep sleep and its preparation side Method.
Background technique
The one third of life is spent in sleep, and only possessing good sleep could maintain normally to live, work And study, it may be said that sleep is to maintain the premise and basis of mankind's activities.Deep sleep be sleep a part, also by Referred to as " gold sleep ", only accounts for the 25% of entire sleeping time.Deep sleep can alleviate people's fatigue in one day, promote people The metabolism of body is very good to body.45-60 years old crowd can undergo a kind of week during this period of time The sex hormone variation of phase property influences the endocrine metabolism imbalance of body, and with angiocarpy, the clinical symptoms of nervous system are main table It is existing.General female just entered into the climacteric period at 45-55 years old, and ovulation and ischomenia lose fecundity, this is primarily due to ovum Nest deterioration so that disappear.Involutional performance, be mainly change in menstrual cycle characteristics before menopause: the menstruation rhythm and pace of moving things changes: the period prolongs Long, intermenstrual period does not come every extension or two, March, restores its natural law after some months again.Menopause is passed through with regular in this way It is alternately present, one, two year can be continued.Mainly have: flush fever creeps up entire face, face since the lower part Often there are significant blood vessel dilatation, rubescent, panhidrosis in portion.Occur dizzy, dizziness simultaneously, flush degree is different, some be limited to face, Neck is rubescent, it is also possible to very frequent and serious.Vegetative dystonie, extremity numbness, especially in night acroparesthesia, convulsion Contraction, lower limb are heavy, two legs seem not know this be placed on where, abdomen pain, nervous, precordial pain is headache, dizzy, insomnia and Syncope;Often have irritable, emotional instability, it is hot-tempered, it is sometimes suspicious with it is depressed.To climacteric, male climacteric can also go out Now similar symptom.It is all with confusion of thinking body basic quality decline of having a sleepless night.Brain worker is long-term.It sleeps abnormal, It stays up late excessively, whole day sleepiness weak all over.Occur simultaneously with diabetes, hypertension, gout chronic diseases in addition to this.Climacteric Phase meeting sex hormone decline, human body can generate corresponding palpitaition, general weakness, dyssomnias, and whole organ functional declines, simultaneously Sleep quality decline, is easy to produce insomnia, it is difficult to deep sleep is carried out, to influence health.
The drug of existing treatment insomnia mainly has barbiturates, Benzodiazepines, Non-benzodiazepine, these early stages Sedative hypnotic drug long-term use is easy to produce according to lazyness, and larger dose can cause dizzy out of strength, dispersion attention, study often Memory capability decline, long-term administration hang-up will appear the adverse reactions such as rebound phenomenon or withrawal symptom.Many Chinese medicines improve and There is long-term clinical application history in terms for the treatment of sleep disturbance, these Chinese Herbs are definite, and adverse reaction is small, have become people The hot spot studied.
For these reasons, the present invention is specifically proposed.
Summary of the invention
In order to solve problem above of the existing technology, the present invention provides a kind of pressed candy for making one deep sleep and Preparation method, pressed candy of the invention is easy to carry, using by environmental restrictions, calm nerves do not promote human body to enter depth Sleep state is spent, the conciliation of female climacteric syndrome is additionally aided.
To achieve the goals above, the present invention adopts the following technical scheme:
A kind of pressed candy making one deep sleep, including the following raw material are made: semen ziziphi spinosae be concentrated powder, royal jelly freeze-dried powder, Powder, γ-aminobutyric acid, ginsenoside powder and auxiliary material is concentrated in jujube.
Further, be made according to parts by weight, including the following raw material: powder 2100-2500 parts by weight, queen bee are concentrated in semen ziziphi spinosae Starch freeze-dried powder 1500-1700 parts by weight, powder 900-1000 parts by weight, γ-aminobutyric acid 55-71 parts by weight, ginseng are concentrated in jujube Stem leaf saponin powder 250-350 parts by weight and auxiliary material 2700-2900 parts by weight.
Further, be made according to parts by weight, including the following raw material: 2288 parts by weight of powder are concentrated in semen ziziphi spinosae, royal jelly freezes 950 parts by weight of powder, 63 parts by weight of γ-aminobutyric acid, 300 weight of ginsenoside powder are concentrated in 1600 parts by weight of dry powder, jujube Part and 2800 parts by weight of auxiliary material.
Semen ziziphi spinosae has significant calm and syngignoscism and anticonvulsant action in semen ziziphi spinosae concentration powder.To cardiovascular system There is significant protective effect, semen ziziphi spinosae aqueous extract has apparent anti-inflammatory effect, mitigates ischemic brain damage.
Jujube be concentrated powder have blood pressure lowering, norcholesterol, adjust body metabolism, strengthen immunity, anti-inflammatory, resistance state is anti- It answers, reduce the effects of blood glucose and cholesterol level;Contained rutin have protection capillary it is unobstructed, prevent vascular wall brittleness increase. Jujube can improve the phagocytic function of internal monocyte, play the role of protecting liver, enhancing physical strength;Vitamin C in jujube, energy Mitigate damage of the chemicals to liver, and have and promote protein synthesis, increases the effect of the Total albumen content.To prevention and treatment bone Matter is loose, anaemia plays an important role, middle-aged and the old's climacteric often osteoporosis, be growing development peak teenager and Women is easy to happen anaemia, and jujube has very ideal dietary function to them, and effect is usually that drug cannot compare. To perfecting capillary, maintaining vessel wall elasticity, antiatherosclerosis is very beneficial;It shows as improving microcirculation in human body, expansion Coronary artery increases the amount of blood supply of brain and heart, and decreasing heart rate reduces myocardial oxygen consumption and improves the metabolism of ischemic myocardium, therefore Cardiovascular and cerebrovascular diseases can be prevented and treated.Jujube can improve the immunity of the human body, and can inhibit cancer cell.It can promote the generation of leucocyte, reduce blood Clearing gallbladder sterol improves seralbumin, protects liver, also containing inhibiting cancer cell in jujube, or even cancer cell can be made to normal The substance of cell transformation.
γ-aminobutyric acid is inhibitory neurotransmitter critically important in central nervous system, it is a kind of naturally occurring Non-protein forms amino acid, has extremely important physiological function, it can promote the reactivity of brain, brain tonic and intelligence development, and anti-epileptic promotees Into sleep, beauty moisturizing delays brain aging function, can supplement human body inhibitory neurotransmitter, has good blood pressure reduction effect. Promote kidney Fitness improvement and protective effect.
Ginsenoside powder stem and leaf of Radix Ginseng saponin can obviously inhibit lipid peroxide in brain and liver to be formed, and reduce brain The content of lipofuscin in cortex and liver;Stem and leaf of Radix Ginseng saponin has antioxidation, and stem and leaf of Radix Ginseng saponin, which has, stablizes membrane structure With increase protein synthesis, memory of the elder ability can be improved.
Further, the auxiliary material is hydroxypropyl methyl cellulose, polyvinyl alcohol, stearic acid, microcrystalline cellulose and difficulty Dissolubility calcium salt or magnesium salts.
Further, according to parts by weight, the auxiliary material is hydroxypropyl methyl cellulose 15-20 parts by weight, polyvinyl alcohol 2-5 parts by weight, stearic acid 2-5 parts by weight, microcrystalline cellulose 10-35 parts by weight and slightly solubility calcium salt or magnesium salts 0-5 parts by weight.
Further, the royal jelly freeze-dried powder is prepared by the following method:
(1) aqueous solution for the mannitol that the concentration of equivalent is 10% will be added in royal jelly, stir evenly, cross 120 meshes Processing;
(2) royal jelly of filtering is fitted into pallet, royal jelly with a thickness of 8-10mm, be freeze-dried;
(3) it is rapidly frozen royal jelly at being -45~-40 DEG C in temperature, keeps royal jelly in the case where vacuum degree is 9-11mmg At a temperature of -23~-27 DEG C, condenser temperature is -48~-52 DEG C, and low temperature is 12-16 hours dry for the first time, by dry room temperature Degree control carries out second of drying at 25-40 DEG C, and second of drying time is 7-10 hours, crushed the processing of 70-90 mesh, envelope Dress obtains the royal jelly freeze-dried powder.
Further, the moisture content in step (3) after drying for the first time in royal jelly is reduced to 7-9%.
Further, the moisture content after second of drying of step (3) in royal jelly is down to 1.5-2.5%.
Royal jelly freeze-dried powder of the invention is prepared by specific preparation condition, not only makes the shelf-life of royal jelly Extend, and also improves the content of the effective component DHA in royal jelly, and make in manufactured pressed candy in DHA It is stabilized, it is not easy to be influenced by external environment.DHA is one of the brain development of people, the important substance of growth, is also simultaneously A kind of Major Nutrient substance nervous system cell growth and maintained, is the important composition ingredient of brain and retina, in human body Content is up to 20% in cerebral cortex, and proportion is maximum in eye retina, accounts for about 50%, to tire infant intelligence and eyesight It develops most important.
Royal jelly freeze-dried powder has the patient of obvious old symptom or even the declining years critically ill patient's good effect worn with age Elderly patient, in the case where conventional medication is ineffective, taking royal jelly freeze-dried powder can pull through.For prolonged illness body The patient to decline has apparent improvement using royal jelly freeze-dried powder, and rehabilitation is quickly.The two-way adjustment of royal jelly freeze-dried powder acts on, It is the blood pressure of hypertensive patient can be down to normally less than all drug, and settles out, it also can be by hypotensive Blood pressure rise to normally, can also settle out;Royal jelly freeze-dried powder has corrective action to cardiovascular system, treats coronary heart disease, brain The disease of cardiovascular systems such as thrombus, cerebral embolism, hypertension, low blood pressure, can play the role of conventional medicine be difficult to play it is peculiar;Bee Royal jelly freeze-dried powder is effective to various rheumatism and other disease of immune system;In clinic, taking royal jelly freeze-dried powder makes very much The woman in menstrual period of too early amenorrhoea has restored that the patient for much losing sexual function is normally made to have restored sexual function.Royal jelly freeze-dried powder It is obvious to the patient outcomes of diabetic and other endocrine disorders;No matter to internal injury, outer wound, royal jelly freeze-dried powder energy Enhancing metabolism promotes histocyte regeneration.Royal jelly freeze-dried powder can make lath sturdy, and fat people can also be made to lose weight;Simultaneously also Has the function of anticancer;The damage caused by radiation and chemotherapy has protective action;It can prevent and treat and be mixed caused by noise on human body function Disorderly.
A kind of preparation method of the pressed candy making one deep sleep, includes the following steps:
(a) it is weighed respectively according to the weight of each raw material spare;
(b) each raw material is uniformly mixed, is successively pelletized, dried, tabletting, is coated, dries in the air piece, packaging.
Further, the processing of 8-12 mesh is crossed in step (b) after granulation.
Further, it is 45-55 DEG C of infra-red drying that step (b) is dry.
Annular sulfided state is presented after each raw material is mixed in container (fluidized bed), is heated air by after purification The alcohol that binder is concentration 90% is atomized and sprays into, makes several particle buildups at the granule containing binder by preheating and mixing, Continuous drying due to hot-air to material evaporates moisture in granule, and adhesive, this process constantly repeats, shape At uniform more micropore spherical particles.
Every 800 milligrams of pressed candy net content of the invention, the first two hour swallows 3-5 piece, warm cold water just before going to bed daily It send down.It is general to require to prepare to fall asleep between 22:30 to 23 points according to everyone different sleep habits.5-30 minutes, mostly Number people can enter deep sleep.It is counted according to clinical test.It is left up to 4-5 hour to take pressed candy deep sleep of the invention It is right.Sleep has been basically completed the physiology course of everyone cerebral metabolism for the first time.Brain memory is clear after 3 points of morning revivals, thinks Dimension is quick, feels salubrious.Enter after having a short interval second and sleep, mainly the fatigue of recovery body physical strength, about three Or so a hour, body completely eliminates fatigue state.Compared with prior art, the invention has the benefit that
(1) pressed candy of the present invention is adjusted body system by the synergistic effect of each raw material, is conducive to heart and brain blood The metabolism of pipe, required nutrition are sufficiently fed, and mainly pass through royal jelly freeze-dried powder and γ-aminobutyric acid collective effect; It is largely to be generated by sex hormone, therefore work as according to each hebetic physiological performance motive power of the principle human body of biological rhythm Human body will generate corresponding palpitaition, general weakness, dyssomnias, whole organ functional when climacteric sex hormone declines Decline, royal jelly freeze-dried powder prepared by the method for the present invention can promote the generation of sex hormone, promote human brain in short-term Interior to enter deep sleep, hetero-organization also can comprehensively adjust the physiological function of each organ of body, and the short time takes energy So that human body sex hormone level during the physiology that sex hormone declines is tended to be steady, reduces involutional abnormal phenomenon;According to Clinical test statistics takes pressed candy deep sleep of the invention up to four hours, and sleep has been basically completed everyone brain The physiology course of metabolism;
(2) all selection integration of drinking and medicinal herbs food is accurately selected raw material of the invention using biology extraction scientific technology There is the Related Component of corrective action for human body, do not add any chemical additives, complies fully with the standard of food;
(3) preparation method of pressed candy of the present invention uses dry granulation, water is not added in whole preparation process, by auxiliary Expect the collective effect between major ingredient, between each raw material be easier to that grain is made, so that when the disintegration of the pressure candy of preparation Between accelerate, and then absorption rate is fast.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical solution of the present invention will be carried out below Detailed description.Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base Embodiment in the present invention, those of ordinary skill in the art are obtained all without making creative work Other embodiment belongs to the range that the present invention is protected.
The manufacturer that powder is concentrated in semen ziziphi spinosae described in the embodiment of the present invention is Nanjing Ze Lang Biotechnology Co., Ltd.
Embodiment 1
A kind of pressed candy making one deep sleep of the present embodiment, including the following raw material are made: powder is concentrated in semen ziziphi spinosae 2100g, royal jelly freeze-dried powder 1500g, jujube concentration powder 900g, γ-aminobutyric acid 55g, ginsenoside powder 250g and auxiliary Expect 2700g, wherein the auxiliary material according to the raw material of following parts by weight for being made: 15 parts by weight of hydroxypropyl methyl cellulose are gathered 2 parts by weight of vinyl alcohol, 2 parts by weight of stearic acid, 10 parts by weight of microcrystalline cellulose;
Wherein, the royal jelly freeze-dried powder the preparation method is as follows:
(1) aqueous solution for the mannitol that the concentration of equivalent is 10% will be added in royal jelly, stir evenly, cross 120 meshes Processing;
(2) royal jelly of filtering is fitted into pallet, royal jelly with a thickness of 8-10mm, be freeze-dried;
(3) it is rapidly frozen royal jelly at being -45 DEG C in temperature, so that royal jelly is maintained at -23 DEG C in the case where vacuum degree is 9mmg At a temperature of, condenser temperature is -48 DEG C, and low temperature is 12 hours dry for the first time, for the first time the moisture content after drying in royal jelly It is reduced to 9%, dry room temperature control is subjected to second of drying at 25 DEG C, second of drying time is 7 hours, and second dry Moisture content after dry in royal jelly is down to 2.5%, crushed the processing of 70 meshes, and encapsulation obtains the royal jelly freeze-dried powder.
The pressed candy for making one deep sleep of the present embodiment the preparation method is as follows:
(a) it is weighed respectively according to the weight of each raw material spare;
(b) each raw material is uniformly mixed, is successively pelletized, crosses the processing of 8 meshes, infra-red drying, tabletting, packet at 45 DEG C Clothing, dry in the air piece, packaging.
Wherein, annular sulfided state will be presented in container (fluidized bed) after the mixing of each raw material, is added by after purification The alcohol that binder is concentration 90% is atomized and sprays into, makes several particle buildups at containing binder by hot-air preheating and mixing Granule, the continuous drying due to hot-air to material evaporates moisture, and adhesive, this process constantly repeats It carries out, forms uniform more micropore spherical particles, granulation is completed.
Embodiment 2
A kind of pressed candy making one deep sleep of the present embodiment, including the following raw material are made: powder is concentrated in semen ziziphi spinosae 2288g, royal jelly freeze-dried powder 1600g, jujube concentration powder 950g, γ-aminobutyric acid 63g, ginsenoside powder 300g and auxiliary Expect 2800g, wherein the auxiliary material according to the raw material of following parts by weight by being made: 17.5 parts by weight of hydroxypropyl methyl cellulose, 3.5 parts by weight of polyvinyl alcohol, 3.5 parts by weight of stearic acid, 22.5 parts by weight of microcrystalline cellulose, 2.5 parts by weight of calcium carbonate;
Wherein, the royal jelly freeze-dried powder the preparation method is as follows:
(1) aqueous solution for the mannitol that the concentration of equivalent is 10% will be added in royal jelly, stir evenly, cross 120 meshes Processing;
(2) royal jelly of filtering is fitted into pallet, royal jelly with a thickness of 8-10mm, be freeze-dried;
(3) it is rapidly frozen royal jelly at being -42.5 DEG C in temperature, so that royal jelly is maintained at -25 in the case where vacuum degree is 10mmg At a temperature of DEG C, condenser temperature is -50 DEG C, and low temperature is 14 hours dry for the first time, and the moisture after drying in royal jelly contains for the first time Amount is reduced to 8%, and dry room temperature control is dry for the second time in 37.5 DEG C of progress, and second of drying time is 8.5 hours, the Moisture content after redrying in royal jelly is down to 2%, crushed the processing of 80 meshes, and encapsulation obtains the royal jelly and freezes Dry powder.
The pressed candy for making one deep sleep of the present embodiment the preparation method is as follows:
(a) it is weighed respectively according to the weight of each raw material spare;
(b) each raw material is uniformly mixed, successively pelletized, cross 10 meshes processing, at 50 DEG C infra-red drying, tabletting, It is coated, dry in the air piece, packaging.
Wherein, annular sulfided state will be presented in container (fluidized bed) after the mixing of each raw material, is added by after purification The alcohol that binder is concentration 90% is atomized and sprays into, makes several particle buildups at containing binder by hot-air preheating and mixing Granule, the continuous drying due to hot-air to material evaporates moisture, and adhesive, this process constantly repeats It carries out, forms uniform more micropore spherical particles, granulation is completed.
Embodiment 3
A kind of pressed candy making one deep sleep of the present embodiment, including the following raw material are made: powder is concentrated in semen ziziphi spinosae 2500g, royal jelly freeze-dried powder 1700g, jujube concentration powder 1000g, γ-aminobutyric acid 71g, ginsenoside powder 350g and auxiliary Expect 2900g, wherein the auxiliary material according to the raw material of following parts by weight for being made: 20 parts by weight of hydroxypropyl methyl cellulose are gathered 5 parts by weight of vinyl alcohol, 5 parts by weight of stearic acid, 35 parts by weight of microcrystalline cellulose, 5 parts by weight of magnesium carbonate;
Wherein, the royal jelly freeze-dried powder the preparation method is as follows:
(1) aqueous solution for the mannitol that the concentration of equivalent is 10% will be added in royal jelly, stir evenly, cross 120 meshes Processing;
(2) royal jelly of filtering is fitted into pallet, royal jelly with a thickness of 8-10mm, be freeze-dried;
(3) it is rapidly frozen royal jelly at being -40 DEG C in temperature, so that royal jelly is maintained at -27 DEG C in the case where vacuum degree is 11mmg At a temperature of, condenser temperature is -52 DEG C, and low temperature is 16 hours dry for the first time, for the first time the moisture content after drying in royal jelly It is reduced to 7%, dry room temperature control is subjected to second of drying at 40 DEG C, second of drying time is 10 hours, second Moisture content after drying in royal jelly is down to 1.5%, crushed the processing of 90 meshes, and encapsulation obtains the royal jelly freeze-drying Powder.
The pressed candy for making one deep sleep of the present embodiment the preparation method is as follows:
(a) it is weighed respectively according to the weight of each raw material spare;
(b) each raw material is uniformly mixed, successively pelletized, cross 12 meshes processing, at 55 DEG C infra-red drying, tabletting, It is coated, dry in the air piece, packaging.
Wherein, annular sulfided state will be presented in container (fluidized bed) after the mixing of each raw material, is added by after purification The alcohol that binder is concentration 90% is atomized and sprays into, makes several particle buildups at containing binder by hot-air preheating and mixing Granule, the continuous drying due to hot-air to material evaporates moisture, and adhesive, this process constantly repeats It carries out, forms uniform more micropore spherical particles, granulation is completed.
Test example 1
Slaking test is carried out to the pressed candy of embodiment 1-3 preparation respectively, disintegration time is measured, the results are shown in Table 1.
Table 1
Group Disintegration time (min)
Embodiment 1 25
Embodiment 2 23
Embodiment 3 24
As can be seen from the above table, pressed candy disintegration time prepared by the present invention is no more than 25min and all dissolves, and illustrates this The pressed candy human body of invention preparation is easy to absorb after taking.
Case 1
Mr. Li, male, 35 years old, the long-term late into the night work of press editor to morning, habituation insomnia, appearance Asia in poor health Health status.Please doctor, nutritionist suggest use the product, overdue three months.Daily 21 points of evening takes the pressure of the preparation of embodiment 1 Piece candy 4, after about two hours, prepare sleep.Enter sleep state within 15 minutes or so.First stage deep sleep about four Brains is clear after a hour wake up, and eyesight understands, closes the eyes for rest, slightly suitable rest about 40 minutes.Gradually it is slept into second stage It sleeps, about three hours wake up naturally.Antisecosis is good, energetic.After taking three months, life is returned to normal Reason state.
Case 2
Liu, female, 53 years old, individual enterprise president, general manager.Operating pressure is big, worries beyond measure, and is in climacteric, there is the phase There is illusion in the performance palpitaition of comprehensive card, hypertension, hyperglycemia, insomnia, thinking.Influence normal life and work.It is built through doctor View takes product normal physiological condition after restoring climacteric, two to three hours after daily supper, according to body for a long time The physiological status of different cycles.Pressed candy three to five for taking the preparation of embodiment 2, can be interrupted use.From when preparing sleep Between start, about half an hour enters first stage deep sleep, this indoor and outdoor moderate sound, illumination is reactionless, indoors three meters it Interior to talk with other people, by the deep sleep of about five hours, conscious, coordination can be slightly living indoors It is dynamic.Enter second stage after quiet rest of lying to regain one's strength until naturally waking up, by adjustment in six months, basic restore just of sleeping Often, blood pressure and blood sugar is all declined, and substantially restores normal work and life state.
Case 3
Sun, female, 20 years old, graduating college entrance examination graduate, diligent senior middle school's study, reading daily in nearly 2 years to the late into the night, length Time sleep is among illusion, bad resting state, causes physical fatigue, memory extremely decline school grade is significantly Decline.Nutrient health Shi Jianyi takes this product.The first two hour takes pressed candy 3- prepared with embodiment 3 just before going to bed every night 4.Prepare sleep to start to call reactionless, slow movement, the not performance of dream up to deep sleep five to ten minutes.First Stage sleep is generally in five hours, after regaining consciousness.Short time enters second stage and sleeps about two hours, this stage is to the external world The sound, illumination is more sensitive, energetic after eliminating fatigue, is swift in motion, arrangement of getting up.It, should by adjustment in one month Student performance is gradually increasing, and hypermnesia, college entrance examination easily obtains good result.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.

Claims (10)

1. a kind of pressed candy for making one deep sleep, which is characterized in that be made including the following raw material: powder, queen bee is concentrated in semen ziziphi spinosae Starch freeze-dried powder, jujube concentration powder, γ-aminobutyric acid, ginsenoside powder and auxiliary material.
2. the pressed candy according to claim 1 for making one deep sleep, which is characterized in that according to parts by weight, including it is as follows Raw material is made: semen ziziphi spinosae is concentrated powder 2100-2500 parts by weight, royal jelly freeze-dried powder 1500-1700 parts by weight, jujube and powder is concentrated 900-1000 parts by weight, γ-aminobutyric acid 55-71 parts by weight, ginsenoside powder 250-350 parts by weight and auxiliary material 2700- 2900 parts by weight.
3. the pressed candy according to claim 2 for making one deep sleep, which is characterized in that according to parts by weight, including it is as follows Raw material is made: semen ziziphi spinosae be concentrated 2288 parts by weight of powder, 1600 parts by weight of royal jelly freeze-dried powder, jujube concentration 950 parts by weight of powder, 2800 parts by weight of 63 parts by weight of γ-aminobutyric acid, 300 parts by weight of ginsenoside powder and auxiliary material.
4. the pressed candy according to claim 1 for making one deep sleep, which is characterized in that the auxiliary material is hydroxypropyl first Base cellulose, polyvinyl alcohol, stearic acid, microcrystalline cellulose and slightly solubility calcium salt or magnesium salts.
5. the pressed candy according to any one of claims 1-4 for making one deep sleep, which is characterized in that the queen bee Slurry freeze-dried powder is prepared by the following method:
(1) aqueous solution for the mannitol that the concentration of equivalent is 10% will be added in royal jelly, stir evenly, cross the processing of 120 meshes;
(2) royal jelly of filtering is fitted into pallet, royal jelly with a thickness of 8-10mm, be freeze-dried;
(3) temperature be -45~-40 DEG C at be rapidly frozen royal jelly, vacuum degree be 9-11mmg under make royal jelly be maintained at - At a temperature of 23~-27 DEG C, condenser temperature is -48~-52 DEG C, and low temperature is 12-16 hours dry for the first time, by dry room temperature control For system in second of drying of 25-40 DEG C of progress, second of drying time is 7-10 hours, crushed the processing of 70-90 mesh, encapsulates, Obtain the royal jelly freeze-dried powder.
6. the pressed candy according to claim 5 for making one deep sleep, which is characterized in that dry for the first time in step (3) The moisture content in royal jelly is reduced to 7-9% afterwards.
7. the pressed candy according to claim 5 for making one deep sleep, which is characterized in that after second of step (3) dry Moisture content in royal jelly is down to 1.5-2.5%.
8. making one the preparation method of the pressed candy of deep sleep described in a kind of claim 1-7 any one, which is characterized in that Include the following steps:
(a) it is weighed respectively according to the weight of each raw material spare;
(b) each raw material is uniformly mixed, is successively pelletized, dried, tabletting, is coated, dries in the air piece, packaging.
9. the preparation method of the pressed candy according to claim 8 for making one deep sleep, which is characterized in that in step (b) The processing of 8-12 mesh is crossed after granulation.
10. the preparation method of the pressed candy according to claim 8 for making one deep sleep, which is characterized in that step (b) is dry Dry is 45-55 DEG C of infra-red drying.
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Application publication date: 20191025