CN110354159A - A kind of Chinese materia medica preparation that treating shingles zoster and preparation method - Google Patents
A kind of Chinese materia medica preparation that treating shingles zoster and preparation method Download PDFInfo
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- CN110354159A CN110354159A CN201810323259.8A CN201810323259A CN110354159A CN 110354159 A CN110354159 A CN 110354159A CN 201810323259 A CN201810323259 A CN 201810323259A CN 110354159 A CN110354159 A CN 110354159A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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- A61K35/648—Myriapods, e.g. centipedes or millipedes
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A61P31/22—Antivirals for DNA viruses for herpes viruses
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Abstract
The invention discloses a kind of Chinese materia medica preparations and preparation method thereof for treating shingles zoster, and active constituent is by weight are as follows: 1-4 parts of borneol, 1-6 parts of alum, 2-7 parts of Semen Cuscutae, 3-9 parts of realgar, 3-9 parts of keel, 1-5 parts of centipede.The preparation method comprises the following steps: 1. mix borneol, alum, Semen Cuscutae, realgar, keel in parts by weight, and finely ground to be ground into medicinal material subdivision, by 100 purpose, No. six are screened, spare；2. the wide-mouth utensil that clay is fired into heats, centipede is placed on baking 1-2 minutes above when surface temperature 20-30 is spent, is turned yellow to centipede color of the leather；3. centipede is finely ground to be ground into medicinal material subdivision, by 100 purpose, No. six are screened, spare；4. the first step and third step preparation gained Chinese materia medica preparation are mixed, lysate is added, finished product is made after mixing evenly.The present invention includes flat nourishing liver and kidney, convergence myogenic, clearing heat and detoxicating, wind-expelling pain-stopping and other effects；It can be used for treating shingles zoster initial stage, mid-term, advanced stage.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, more particularly to a kind of Chinese materia medica preparation for treating shingles zoster and preparation
Method.
Background technique
Shingles zoster is the acute infection dermatoses as caused by varicella virus VZV.To this virus without immune
After the children of power are infected, varicella occurs.Become carrier after some patientss are infected without symptom.Since virus has
Have neurotropism, can hide for a long time after infection in the neuron of spinal nerve posterior root ganglion, when it is lower for the resistance or tired,
When infection, flu, virus can regrow breeding, and move to skin along nerve fibre, generate the nerve invaded and skin
Strong inflammation.Fash generally has Unilateral and the characteristics of be distributed by nerve segment, is made of the bleb of cluster, and with pain
Bitterly；Age is bigger, and neuralgia is heavier.This disease is apt to occur in adult, and season in spring and autumn is common.Disease incidence is on significant with age increase
It rises.
People is the only host of varicella virus, and virus enters blood through respiratory mucosa and forms viremia virusemia,
Varicella occurs or in subclinical infection, can be hidden for a long time with restrovirus in spinal cord posterior root ganglion or ganglia sensorialia nervi encephalici
It is interior.When body is caused Abwehrkraft des Koepers to decline by certain stimulation (such as wound, fatigue, malignant tumour or eak after being ill),
Latent virus is activated, and duplication generates blister along the skin that sensory nerve axon downlink reaches the dominated region of the nerve, together
When be involved nerve to occur inflammation, necrosis, generate neuralgia.Originally available more lasting after recovering to be immunized, therefore will not generally send out again.
Currently, western medical treatment method be divided into antiviral therapy, glucocorticoid therapy, neuralgic treatment local treatment,
Physiotherapy, PHN treatment, cranial nerve involvement treatment, children and teen-age HZ, the treatment of gestational period HZ, immune deficient patients
HZ treatment, the treatment of HZ drug resistant to antiviral drugs.Common anti-herpesvirus medicament have acyclovir, Valaciclovir and
Famciclovir, high dose glucocorticoid class drug, PHN patient's duration, violent pain often need to take the anti-suppression of tricyclic antidepressants
Strongly fragrant medicine, antiepileptic, opioid analgesics etc., but may cause the adverse reaction of whole body, and moderate pain can only be mitigated；Chinese medicine
It treats HZ and uses dialectical treatment, first is that with activating microcirculation and removing stasis medicinal, but eliminating evil dredging collateral method, third is that righting method.The drug of use has tranquilizing the mind
Medicine, insects dredging collateral medicine and for checking and affirm and the medication of site of pathological change.
Summary of the invention
It is an object of the invention to provide a kind of Chinese materia medica preparation for treating shingles zoster and preparation methods, can be to band-like blister
Rash has quite good treatment.
The purpose of the present invention is realized by following technical proposals: a kind of Chinese materia medica preparation for treating shingles zoster, activity
Ingredient is by weight are as follows: and 1-4 parts of borneol, 1-6 parts of alum, 2-7 parts of Semen Cuscutae, 3-9 parts of realgar, 3-9 parts of keel, centipede 1-5
Part.
As one of preferred embodiment, active constituent is by weight are as follows: 1-2 parts of borneol, 1-3 parts of alum, Tu
It is 2-4 parts sub-, 4-8 parts of realgar, 4-8 parts of keel, 1-3 parts of centipede.
As further specific preferred embodiment, active constituent is by weight are as follows: 2 parts of borneol, 2 parts of alum, Tu
3 parts, 5 parts of realgar, 5 parts of keel, 1 part of centipede of son.
As further specific preferred embodiment, active constituent is by weight are as follows: 3 parts of borneol, 5 parts of alum, Tu
7 parts, 8 parts of realgar, 8 parts of keel, 2 parts of centipede of son.
Further, the Chinese materia medica preparation is emulsifiable paste, spray or liniment.
A method of being used to prepare treatment shingles zoster Chinese materia medica preparation, it is characterised in that: active constituent is by weight
Are as follows: 1-4 parts of borneol, 1-6 parts of alum, 2-7 parts of Semen Cuscutae, 3-9 parts of realgar, 3-9 parts of keel, 1-5 parts of centipede, the preparation method
The following steps are included:
First step mixes borneol, alum, Semen Cuscutae, realgar, keel in parts by weight, and finely ground to be ground into medicinal material thin
Point, by 100 purpose, No. six are screened, spare；
The wide-mouth utensil that clay is fired by second step heats, and centipede is placed on baking above when surface temperature 20-30 is spent
1-2 minutes, turn yellow to centipede color of the leather；
Third step centipede is finely ground to be ground into medicinal material subdivision, and by 100 purpose, No. six are screened, spare；
4th step mixes the first step and third step preparation gained Chinese materia medica preparation, and lysate is added, is made after mixing evenly
Finished product.
As one of further preferred embodiment, the lysate is mature vinegar, which is after brewing well, to store more than half a year
Shanxi mature vinegar, dosage 5-20ml.
As one of further preferred embodiment, the lysate is ethanol solution, and alcoholic strength 30-95%, dosage is
5-20ml。
As one of further preferred embodiment, the lysate is vaseline, and dosage is 2-10 grams.
Compared with prior art, the beneficial effects of the present invention are: the present invention to include flat nourishing liver and kidney, convergence myogenic, heat-clearing
Removing toxic substances, wind-expelling pain-stopping and other effects；It can be used for treating shingles zoster initial stage, mid-term, advanced stage；The preparation method through the invention
The Chinese drugs agentia can be made to emulsifiable paste, spray, liniment etc., be easy to use.
Specific embodiment
The present invention is further illustrated combined with specific embodiments below.
Embodiment 1:
A kind of Chinese materia medica preparation for treating shingles zoster, active constituent is by weight are as follows: and 2 parts of borneol, 2 parts of alum, Tu
3 parts, 5 parts of realgar, 5 parts of keel, 1 part of centipede of silk.Wherein, 1 part of centipede is whole medium sized centipede.
The preparation method of the treatment shingles zoster Chinese materia medica preparation the following steps are included:
First step mixes borneol, alum, Semen Cuscutae, realgar, keel in parts by weight, and finely ground to be ground into medicinal material thin
Point, by 100 purpose, No. six are screened, spare；
The wide-mouth utensil that clay is fired by second step heats, and centipede is placed on baking above when surface temperature 20-30 is spent
1 minute, turn yellow to centipede color of the leather；
Third step centipede is finely ground to be ground into medicinal material subdivision, and by 100 purpose, No. six are screened, spare；
4th step mixes the first step and third step preparation gained Chinese materia medica preparation, and lysate is added, in the present embodiment,
The lysate is mature vinegar, which is storage Shanxi mature vinegar more than half a year after brewing well, dosage 5-20ml；Mixing
After uniformly, it is put into bottle and emulsion or spray is made.
Usage and dosage: appropriate apply is taken to put affected part on the skin, once a day；Serious person is twice a day.
The present invention includes flat nourishing liver and kidney, convergence myogenic, clearing heat and detoxicating, wind-expelling pain-stopping and other effects；It can be used for treating band-like blister
Rash initial stage, mid-term, advanced stage.
Embodiment 2:
A kind of Chinese materia medica preparation for treating shingles zoster, active constituent is by weight are as follows: and 3 parts of borneol, 5 parts of alum, Tu
7 parts, 8 parts of realgar, 8 parts of keel, 2 parts of centipede of silk.Wherein, 2 parts of centipedes are two medium sized centipedes.
The preparation method of the treatment shingles zoster Chinese materia medica preparation the following steps are included:
First step mixes borneol, alum, Semen Cuscutae, realgar, keel in parts by weight, and finely ground to be ground into medicinal material thin
Point, by 100 purpose, No. six are screened, spare；
The wide-mouth utensil that clay is fired by second step heats, and centipede is placed on baking above when surface temperature 20-30 is spent
1 minute, turn yellow to centipede color of the leather；
Third step centipede is finely ground to be ground into medicinal material subdivision, and by 100 purpose, No. six are screened, spare；
4th step mixes the first step and third step preparation gained Chinese materia medica preparation, and lysate is added, in the present embodiment,
The lysate is ethanol solution, alcoholic strength 30-95%, dosage 5-20ml；After mixing, it is put into bottle and cream is made
Agent or spray.
Usage and dosage: appropriate apply is taken to put affected part on the skin, once a day；Serious person is twice a day.
The present invention includes flat nourishing liver and kidney, convergence myogenic, clearing heat and detoxicating, wind-expelling pain-stopping and other effects；It can be used for treating band-like blister
Rash initial stage, mid-term, advanced stage.
Embodiment 3:
A kind of Chinese materia medica preparation for treating shingles zoster, active constituent is by weight are as follows: and 2 parts of borneol, 3 parts of alum, Tu
4 parts, 8 parts of realgar, 8 parts of keel, 3 parts of centipede of silk.Wherein, 3 parts of centipedes are 3 medium sized centipedes.
The preparation method of the treatment shingles zoster Chinese materia medica preparation the following steps are included:
First step mixes borneol, alum, Semen Cuscutae, realgar, keel in parts by weight, and finely ground to be ground into medicinal material thin
Point, by 100 purpose, No. six are screened, spare；
The wide-mouth utensil that clay is fired by second step heats, and centipede is placed on baking above when surface temperature 20-30 is spent
1 minute, turn yellow to centipede color of the leather；
Third step centipede is finely ground to be ground into medicinal material subdivision, and by 100 purpose, No. six are screened, spare；
4th step mixes the first step and third step preparation gained Chinese materia medica preparation, and lysate is added, in the present embodiment,
The lysate is vaseline, and dosage is 2-10 grams.After mixing, it is put into bottle and emulsion or liniment is made.
Usage and dosage: appropriate apply is taken to put affected part on the skin, once a day；Serious person is twice a day.
Result in clinical application: this prescription clinic treats Patients with Herpes Zoster 53 altogether, wherein male 31, female 22, wherein
Age is 11 years old minimum, 73 years old maximum.53 patients all cure, and cure rate is very.Analgesic time is most 1 day short, and longest 3 days,
Fash incrustation is most 2 days short, and longest 4 days.There is sequelae (nerve pain and cutaneous pigmentation) in no an example.In this 53 patients
In there are 6 patients to be single in intravenous drip Acyclovir injection and after pain does not mitigate after external application Virless Cream 4-6 days
It solely uses, effect is obvious.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Made any modifications, equivalent replacements, and improvements etc., should all be included in the protection scope of the present invention within mind and principle.
Claims (9)
1. a kind of Chinese materia medica preparation for treating shingles zoster, it is characterised in that: its active constituent is by weight are as follows: 1-4 parts of borneol,
1-6 parts of alum, 2-7 parts of Semen Cuscutae, 3-9 parts of realgar, 3-9 parts of keel, 1-5 parts of centipede.
2. the Chinese materia medica preparation for the treatment of shingles zoster as described in claim 1, it is characterised in that: its active constituent is by weight
Are as follows: 1-2 parts of borneol, 1-3 parts of alum, 2-4 parts of Semen Cuscutae, 4-8 parts of realgar, 4-8 parts of keel, 1-3 parts of centipede.
3. the Chinese materia medica preparation for the treatment of shingles zoster as claimed in claim 2, it is characterised in that: its active constituent is by weight
Are as follows: 2 parts of borneol, 2 parts of alum, 3 parts of Semen Cuscutae, 5 parts of realgar, 5 parts of keel, 1 part of centipede.
4. the Chinese materia medica preparation for the treatment of shingles zoster as described in claim 1, it is characterised in that: its active constituent is by weight
Are as follows: 3 parts of borneol, 5 parts of alum, 7 parts of Semen Cuscutae, 8 parts of realgar, 8 parts of keel, 2 parts of centipede.
5. the Chinese materia medica preparation of the treatment shingles zoster as described in any in claim 1-4, it is characterised in that: the Chinese materia medica preparation
For emulsifiable paste, spray or liniment.
6. a kind of method for being used to prepare treatment shingles zoster Chinese materia medica preparation, it is characterised in that: active constituent is by weight are as follows:
1-4 parts of borneol, 1-6 parts of alum, 2-7 parts of Semen Cuscutae, 3-9 parts of realgar, 3-9 parts of keel, 1-5 parts of centipede, the preparation method packet
Include following steps:
First step mixes borneol, alum, Semen Cuscutae, realgar, keel in parts by weight, finely ground to be ground into medicinal material subdivision, leads to
100 purpose six is crossed to be screened, it is spare；
The wide-mouth utensil that clay is fired by second step heats, and centipede is placed on when surface temperature 20-30 is spent and toasts 1-2 above
Minute, turn yellow to centipede color of the leather；
Third step centipede is finely ground to be ground into medicinal material subdivision, and by 100 purpose, No. six are screened, spare；
4th step mixes the first step and third step preparation gained Chinese materia medica preparation, and lysate is added, is made into after mixing evenly
Product.
7. being used to prepare the method for the treatment of shingles zoster Chinese materia medica preparation as claimed in claim 6, it is characterised in that: the dissolution
Liquid is mature vinegar, which is storage Shanxi mature vinegar more than half a year after brewing well, dosage 5-20ml.
8. being used to prepare the method for the treatment of shingles zoster Chinese materia medica preparation as claimed in claim 6, it is characterised in that: the dissolution
Liquid is ethanol solution, alcoholic strength 30-95%, dosage 5-20ml.
9. being used to prepare the method for the treatment of shingles zoster Chinese materia medica preparation as claimed in claim 6, it is characterised in that: the dissolution
Liquid is vaseline, and dosage is 2-10 grams.
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Citations (7)
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2018
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| CN101129866A (en) * | 2007-08-08 | 2008-02-27 | 江蕾 | Method of preparing externally-painting medicine for treating zoster |
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| CN105497077A (en) * | 2015-12-22 | 2016-04-20 | 王凯 | Ointment for treating herpes zoster |
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Application publication date: 20191022 |