CN110339281A - A kind of Chinese medicine hemostatic formulations and preparation method thereof - Google Patents
A kind of Chinese medicine hemostatic formulations and preparation method thereof Download PDFInfo
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- 239000003814 drug Substances 0.000 title claims abstract description 31
- 230000002439 hemostatic effect Effects 0.000 title claims abstract description 22
- 239000000203 mixture Substances 0.000 title claims abstract description 21
- 238000002360 preparation method Methods 0.000 title claims abstract description 21
- 238000009472 formulation Methods 0.000 title claims abstract description 19
- 235000003717 Boswellia sacra Nutrition 0.000 claims abstract description 10
- 240000007551 Boswellia serrata Species 0.000 claims abstract description 10
- 235000012035 Boswellia serrata Nutrition 0.000 claims abstract description 10
- 240000007311 Commiphora myrrha Species 0.000 claims abstract description 10
- 235000006965 Commiphora myrrha Nutrition 0.000 claims abstract description 10
- 239000004863 Frankincense Substances 0.000 claims abstract description 10
- 235000007265 Myrrhis odorata Nutrition 0.000 claims abstract description 10
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 10
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 10
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 8
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 8
- 241000489492 Arisaema Species 0.000 claims abstract description 8
- 241000131329 Carabidae Species 0.000 claims abstract description 8
- 235000003255 Carthamus tinctorius Nutrition 0.000 claims abstract description 8
- 244000020518 Carthamus tinctorius Species 0.000 claims abstract description 8
- 241001043298 Croton draco Species 0.000 claims abstract description 8
- 241000244987 Daiswa polyphylla Species 0.000 claims abstract description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 8
- 210000000941 bile Anatomy 0.000 claims abstract description 8
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 8
- 229940116229 borneol Drugs 0.000 claims abstract description 8
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 8
- 210000000078 claw Anatomy 0.000 claims abstract description 8
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000009136 dragon's blood Substances 0.000 claims abstract description 8
- 210000000582 semen Anatomy 0.000 claims abstract description 8
- 229940126678 chinese medicines Drugs 0.000 claims abstract description 5
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229920002125 Sokalan® Polymers 0.000 claims abstract description 4
- 239000002775 capsule Substances 0.000 claims abstract description 4
- 229960001631 carbomer Drugs 0.000 claims abstract description 4
- 238000000605 extraction Methods 0.000 claims abstract description 4
- 239000012530 fluid Substances 0.000 claims abstract description 4
- 239000004615 ingredient Substances 0.000 claims abstract description 4
- 239000007788 liquid Substances 0.000 claims abstract description 4
- 238000001556 precipitation Methods 0.000 claims abstract description 4
- 239000008280 blood Substances 0.000 claims description 13
- 210000004369 blood Anatomy 0.000 claims description 13
- 230000023597 hemostasis Effects 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 238000001035 drying Methods 0.000 abstract description 2
- 230000000025 haemostatic effect Effects 0.000 abstract description 2
- 238000003801 milling Methods 0.000 abstract description 2
- 230000000144 pharmacologic effect Effects 0.000 abstract description 2
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- 231100000319 bleeding Toxicity 0.000 description 6
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- 208000000616 Hemoptysis Diseases 0.000 description 2
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- 206010053615 Thermal burn Diseases 0.000 description 2
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- 230000003213 activating effect Effects 0.000 description 2
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- 208000034526 bruise Diseases 0.000 description 2
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- 206010033675 panniculitis Diseases 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 230000002040 relaxant effect Effects 0.000 description 2
- 230000000552 rheumatic effect Effects 0.000 description 2
- 210000000697 sensory organ Anatomy 0.000 description 2
- 231100000075 skin burn Toxicity 0.000 description 2
- 210000004872 soft tissue Anatomy 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 description 2
- 210000002435 tendon Anatomy 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 1
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- 239000003130 blood coagulation factor inhibitor Substances 0.000 description 1
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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Abstract
The invention discloses a kind of Chinese medicine hemostatic formulations and preparation method thereof, the Chinese medicine hemostatic formulations ingredient and consumption proportion are as follows: 3~4 parts of Rhizoma Chuanxiong, 1~3 part of Radix Angelicae Sinensis, 6~10 parts of frankincense, 6~8 parts of myrrh, 3~5 parts of arisaema cum bile, 1~3 part of ground beetle, 3~5 parts of dragon's blood, wild 3~5 parts of radix saposhnikoviae, 3~5 parts of crab claw bone, 3~5 parts of safflower, 1~3 part of Rhizoma Et Radix Notopterygii, 0.5~1 part of Semen Strychni (processed), 6~9 parts of Radix Notoginseng, 3~5 parts of Paris polyphylla, 3~5 parts of cimicifugae foetidae, 0.3~0.5 part of borneol, 9~12 parts of rhizoma cibotii.The preparation method comprises the following steps: taking all kinds of Chinese medicine drying millings of aforementioned proportion, be sieved 80 mesh, is packed into No. 1 capsule；Take all kinds of Chinese medicines of aforementioned proportion, will three times decocting liquid mix after, alcohol precipitation alcohol takes, be added carbomer, gel is made；All kinds of Chinese medicine low-temperature extractions of aforementioned proportion are taken, medical fluid is obtained, is made into spray-type.Formula haemostatic effect of the present invention is obvious, and is configured by Chinese medicine, and pharmacological property is mild, Small side effects.
Description
Technical field
The present invention relates to Chinese medicine preparation and preparation method thereof, a kind of Chinese medicine hemostatic formulations and preparation method thereof are specifically referred to.
Background technique
All drugs that can promote blood clotting and make stopped bleeding, referred to as hemostatic.Hemostatic mainly passes through in reinforcement
Coagulation factor inhibits anticoagulant factor, promotes blood coagulation, to reach hemostasis purpose.Blood is in heart and Endovascular recycle stream
A kind of dynamic tissue, the disease of all bleedings, especially Venous Arterial are bled profusely, such as effective not in time to prevent, and blood is caused to consume
Damage, and cause body weak or even threat to life.So the application of hemostatic is of great significance.
Summary of the invention
The technical problem to be solved in the present invention is that providing a kind of Chinese medicine hemostatic formulations and preparation method thereof, haemostatic effect
Obviously, and by Chinese medicine it configures, pharmacological property is mild, Small side effects.
The used technical solution is as follows:
A kind of Chinese medicine hemostatic formulations and preparation method thereof,
The Chinese medicine hemostatic formulations ingredient and consumption proportion are as follows: 3~4 parts of Rhizoma Chuanxiong, 1~3 part of Radix Angelicae Sinensis, 6~10 parts of frankincense,
6~8 parts of myrrh, 3~5 parts of arisaema cum bile, 1~3 part of ground beetle, 3~5 parts of dragon's blood, wild 3~5 parts of radix saposhnikoviae, 3~5 parts of crab claw bone,
3~5 parts of safflower, 1~3 part of Rhizoma Et Radix Notopterygii, 0.5~1 part of Semen Strychni (processed), 6~9 parts of Radix Notoginseng, 3~5 parts of Paris polyphylla, 3~5 parts of cimicifugae foetidae, borneol
0.3~0.5 part, 9~12 parts of rhizoma cibotii.
As further explanation,
The Chinese medicine hemostatic formulations ingredient and consumption proportion are as follows: 3 parts of Rhizoma Chuanxiong, 1 part of Radix Angelicae Sinensis, 6 parts of frankincense, myrrh 6
Part, 3 parts of arisaema cum bile, 1 part of ground beetle, 3 parts of dragon's blood, wild 3 parts of radix saposhnikoviae, 3 parts of crab claw bone, 3 parts of safflower, 1 part of Rhizoma Et Radix Notopterygii, Semen Strychni (processed)
0.5 part, 6 parts of Radix Notoginseng, 3 parts of Paris polyphylla, 3 parts of cimicifugae foetidae, 0.3 part of borneol, 9 parts of rhizoma cibotii.
As further explanation,
The Chinese medicine hemostatic formulations are milled the preparation method comprises the following steps: all kinds of Chinese medicines of aforementioned proportion is taken to dry, and be sieved 80 mesh, is packed into
No. 1 capsule.
As further explanation,
The Chinese medicine hemostatic formulations the preparation method comprises the following steps: take all kinds of Chinese medicines of aforementioned proportion, will be after decocting liquid mixes three times, alcohol precipitation
Alcohol takes, and carbomer is added, gel is made.
As further explanation,
The Chinese medicine hemostatic formulations the preparation method comprises the following steps: take all kinds of Chinese medicine low-temperature extractions of aforementioned proportion, obtain medical fluid, be made into
Spray-type.
A kind of Chinese medicine hemostatic formulations of the present invention and preparation method thereof have the advantages that
1. formula of the present invention is used for palace blood, menorrhalgia, hemorrhoid blood, hematochezia, knife wound bleeding, bleeding from five sense organs or subcutaneous tissue, hemoptysis, alimentary canal
Bleeding is intracranialed hemorrhage, the local application of soft tissue bruise and blood stasis and swelling pain, closed fracture and skin burn, scald.Match
Rhizoma Chuanxiong, myrrh contained in side can stop blooding dissolving stasis, swelling and pain relieving；Frankincense can be with relaxing tendons and activating collaterals promoting the circulation of qi；Radix Notoginseng can be stopped
Blood, blood-breaking dissipate the stasis of blood, anti-inflammatory analgesic therapy；Rhizoma cibotii can be used for rheumatic arthralgia, soreness and weakness of waist and knees.
It is small to injury of gastrointestinal tract 2. be formulated safety, Small side effects belonging to of the invention, can external application also oral administration, to liver kidney
Dirty stimulation is small.
Specific embodiment
Technical solution of the present invention specifically, is completely illustrated below.
Embodiment 1:
Take 3 parts of Rhizoma Chuanxiong, it is 1 part of Radix Angelicae Sinensis, 6 parts of frankincense, 6 parts of myrrh, 3 parts of arisaema cum bile, 1 part of ground beetle, 3 parts of dragon's blood, wild
3 parts of radix saposhnikoviae, 3 parts of crab claw bone, 3 parts of safflower, 1 part of Rhizoma Et Radix Notopterygii, 0.5 part of Semen Strychni (processed), 6 parts of Radix Notoginseng, 3 parts of Paris polyphylla, 3 parts of cimicifugae foetidae, borneol
0.3 part, 9 parts of drying millings of rhizoma cibotii, be sieved 80 mesh, is packed into No. 1 capsule.
Embodiment 2:
Take 3 parts of Rhizoma Chuanxiong, it is 1 part of Radix Angelicae Sinensis, 6 parts of frankincense, 6 parts of myrrh, 3 parts of arisaema cum bile, 1 part of ground beetle, 3 parts of dragon's blood, wild
3 parts of radix saposhnikoviae, 3 parts of crab claw bone, 3 parts of safflower, 1 part of Rhizoma Et Radix Notopterygii, 0.5 part of Semen Strychni (processed), 6 parts of Radix Notoginseng, 3 parts of Paris polyphylla, 3 parts of cimicifugae foetidae, borneol
0.3 part, 9 parts of rhizoma cibotii will three times decocting liquid mix after, alcohol precipitation alcohol takes, be added carbomer, gel is made.
Embodiment 3:
Take 3 parts of Rhizoma Chuanxiong, it is 1 part of Radix Angelicae Sinensis, 6 parts of frankincense, 6 parts of myrrh, 3 parts of arisaema cum bile, 1 part of ground beetle, 3 parts of dragon's blood, wild
3 parts of radix saposhnikoviae, 3 parts of crab claw bone, 3 parts of safflower, 1 part of Rhizoma Et Radix Notopterygii, 0.5 part of Semen Strychni (processed), 6 parts of Radix Notoginseng, 3 parts of Paris polyphylla, 3 parts of cimicifugae foetidae, borneol
0.3 part, 9 parts of low-temperature extractions of rhizoma cibotii obtain medical fluid, are made into spray-type.
1. formula of the present invention is used for palace blood, menorrhalgia, hemorrhoid blood, hematochezia, knife wound bleeding, bleeding from five sense organs or subcutaneous tissue, hemoptysis, alimentary canal
Bleeding is intracranialed hemorrhage, the local application of soft tissue bruise and blood stasis and swelling pain, closed fracture and skin burn, scald.Match
Rhizoma Chuanxiong, myrrh contained in side can stop blooding dissolving stasis, swelling and pain relieving；Frankincense can be with relaxing tendons and activating collaterals promoting the circulation of qi；Radix Notoginseng can be stopped
Blood, blood-breaking dissipate the stasis of blood, anti-inflammatory analgesic therapy；Rhizoma cibotii can be used for rheumatic arthralgia, soreness and weakness of waist and knees.
It is small to injury of gastrointestinal tract 2. be formulated safety, Small side effects belonging to of the invention, can external application also oral administration, to liver kidney
Dirty stimulation is small.
The foregoing describe basic principles and main features of the invention, It should be understood by those skilled in the art that of the invention
It is not restricted to the described embodiments, the above embodiments and description only illustrate the principle of the present invention, is not departing from
Under the premise of spirit and scope of the invention, various changes and improvements may be made to the invention, these changes and improvements both fall within requirement
In the scope of the invention of protection, invents claimed range and be defined by the appending claims and its equivalent thereof.
Claims (5)
1. a kind of Chinese medicine hemostatic formulations and preparation method thereof, which is characterized in that the Chinese medicine hemostatic formulations ingredient and consumption proportion
Are as follows: 3~4 parts of Rhizoma Chuanxiong, 1~3 part of Radix Angelicae Sinensis, 6~10 parts of frankincense, 6~8 parts of myrrh, 3~5 parts of arisaema cum bile, ground beetle 1~3
Part, 3~5 parts of dragon's blood, wild 3~5 parts of radix saposhnikoviae, 3~5 parts of crab claw bone, 3~5 parts of safflower, 1~3 part of Rhizoma Et Radix Notopterygii, Semen Strychni (processed) 0.5~1
Part, 6~9 parts of Radix Notoginseng, 3~5 parts of Paris polyphylla, 3~5 parts of cimicifugae foetidae, 0.3~0.5 part of borneol, 9~12 parts of rhizoma cibotii.
2. a kind of Chinese medicine hemostatic formulations according to claim 1 and preparation method thereof, which is characterized in that the Chinese medicine stops
Blood formula components and consumption proportion are as follows: 3 parts of Rhizoma Chuanxiong, 1 part of Radix Angelicae Sinensis, 6 parts of frankincense, 6 parts of myrrh, 3 parts of arisaema cum bile, ground beetle 1
Part, 3 parts of dragon's blood, wild 3 parts of radix saposhnikoviae, 3 parts of crab claw bone, 3 parts of safflower, 1 part of Rhizoma Et Radix Notopterygii, 0.5 part of Semen Strychni (processed), 6 parts of Radix Notoginseng, 3 parts of Paris polyphylla,
3 parts of cimicifugae foetidae, 0.3 part of borneol, 9 parts of rhizoma cibotii.
3. a kind of Chinese medicine hemostatic formulations according to claim 1 and preparation method thereof, which is characterized in that the Chinese medicine hemostasis
Formula is milled the preparation method comprises the following steps: all kinds of Chinese medicines of aforementioned proportion is taken to dry, and be sieved 80 mesh, is packed into No. 1 capsule.
4. a kind of Chinese medicine hemostatic formulations according to claim 1 and preparation method thereof, which is characterized in that the Chinese medicine hemostasis
Formula the preparation method comprises the following steps: take all kinds of Chinese medicines of aforementioned proportion, will be after decocting liquid mixes three times, alcohol precipitation alcohol takes, and carbomer is added, is made
Gel.
5. a kind of Chinese medicine hemostatic formulations according to claim 1 and preparation method thereof, which is characterized in that the Chinese medicine hemostasis
Formula the preparation method comprises the following steps: take all kinds of Chinese medicine low-temperature extractions of aforementioned proportion, obtain medical fluid, be made into spray-type.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112089794A (en) * | 2020-10-30 | 2020-12-18 | 广东宇通医药生物科技有限公司 | Traditional Chinese medicine hemostatic formula and preparation method thereof |
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| CN1066783A (en) * | 1991-05-13 | 1992-12-09 | 赵俊光 | The preparation method of traumatic quick result medicine |
| CN101181526A (en) * | 2007-11-26 | 2008-05-21 | 倪建忠 | Medical hongshang hemostatic medicament and preparation method thereof |
| CN103989864A (en) * | 2014-04-30 | 2014-08-20 | 烟台恒迪克能源科技有限公司 | Externally-applied pain-relieving swelling-removing ointment for traumatic injuries and preparation method thereof |
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2019
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1066783A (en) * | 1991-05-13 | 1992-12-09 | 赵俊光 | The preparation method of traumatic quick result medicine |
| CN101181526A (en) * | 2007-11-26 | 2008-05-21 | 倪建忠 | Medical hongshang hemostatic medicament and preparation method thereof |
| CN103989864A (en) * | 2014-04-30 | 2014-08-20 | 烟台恒迪克能源科技有限公司 | Externally-applied pain-relieving swelling-removing ointment for traumatic injuries and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112089794A (en) * | 2020-10-30 | 2020-12-18 | 广东宇通医药生物科技有限公司 | Traditional Chinese medicine hemostatic formula and preparation method thereof |
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Application publication date: 20191018 |