CN110305783A - One kind being based on biotechnology gene assaying device - Google Patents

One kind being based on biotechnology gene assaying device Download PDF

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Publication number
CN110305783A
CN110305783A CN201910656893.8A CN201910656893A CN110305783A CN 110305783 A CN110305783 A CN 110305783A CN 201910656893 A CN201910656893 A CN 201910656893A CN 110305783 A CN110305783 A CN 110305783A
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test tube
loading plate
mounting
component
motor
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陈龙刚
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

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  • Life Sciences & Earth Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention discloses one kind to be based on biotechnology gene assaying device, belongs to technical field of medical equipment.It include loading plate, test tube position-limit mechanism, test tube cleaning, drying mechanism, test tube tipping mechanism and test tube acquisition testing mechanism, the lower section of the loading plate is equipped with recycling funnel, the bottom of recycling funnel is equipped with and its internal reflux line being connected to, test tube acquisition testing mechanism includes portal frame, acquisition component, clasmatosis component, moves material platform and move material component, it is set at the top of portal frame there are two connecting plate, sets that there are two support rods between two connecting plates.The beneficial effects of the invention are as follows can carry out clasmatosis operation respectively to each test tube automatically by test tube acquisition testing mechanism, it can also realize automatically and each test tube is detected respectively, worker is set to can be derived that the testing result of each test tube, the genetic test efficiency to cell liquid is improved, and invisible spectro cleaning solution can be enable automatically to pour out by test tube tipping mechanism.

Description

One kind being based on biotechnology gene assaying device
Technical field
The present invention relates to technical field of medical equipment, are specifically related to a kind of based on biotechnology gene assaying device.
Background technique
In field of biotechnology, genetic test is the important means of life studies, is done at present universal when gene detection assay Using the method for unimolecule gene sequencing, and the fluid control device of unimolecule gene sequencing is the key that unimolecule tester mould Block, the genetic chip in the fluid control device of unimolecule gene sequencing are the cores for carrying out biochemical reaction and optical imagery Multiple fluid delivery devices are usually arranged in part, the fluid control device of gene sequencing, which has to gene core Piece conveys the functions such as various reaction reagents, control reagent flow direction and flow, the mixing for controlling reagent, export waste liquid.Traditional Gene assaying device is difficult to that the test tube after the completion of genetic test is cleaned and dried automatically, and worker is needed to grasp manually Make, and traditional gene assaying device function is more single, does not have the crushing function to cell such as, need to improve.
Such as a kind of biotechnology gene assaying device of disclosure of the invention of Publication No. CN106434318A, including work Platform, detection case, test tube and genetic test module, the detection case setting are on the table, corresponding in the detection case to open door Body is provided with sliding slot, and test tube snap-gauge is movably set on the sliding slot, and several test tube cards are evenly arranged on test tube snap-gauge Mouthful, the test tube is placed in test tube bayonet, and interface is provided with perfusion tube, the input of the interface at the top of the detection case End is connected with drawing liquid pump and suction pump, and the output end of the drawing liquid pump is connect by connecting tube with genetic test module, the pumping The input terminal of water pump is connected with clear water tanks by water inlet pipe, and the input terminal of the suction pump and the output end of drawing liquid pump electrically connect It connects.The biotechnology gene assaying device, it is easy to operate, a possibility that examination liquid in pipe is contaminated is reduced, liquid base is improved Because of the accuracy of detection.
But above-mentioned apparatus is also there is a problem that first, above-mentioned apparatus can only be once to all invisible spectro cells Liquid is detected, and cannot achieve the detection respectively to multiple test tube inner cell liquid, affects the accuracy of cytogene detection;The Two, above-mentioned apparatus is difficult to realize the crushing operation to cell, makes cell that can not release its internal DNA fragmentation, needs to carry out It improves;Third, above-mentioned apparatus are difficult to topple over the test tube after cleaning, need worker manually by invisible spectro liquid pouring And test tube is dried, brings biggish trouble for worker.
Summary of the invention
Technical problem to be solved by the invention is to provide one kind to be based on biotechnology gene assaying device, to solve nothing Method realizes the technical issues of crushing operation for detecting and being difficult to realize respectively to cell to multiple test tube inner cell liquid.
In order to solve the above technical problems, the present invention the following technical schemes are provided: include loading plate, test tube position-limit mechanism, Test tube cleaning, drying mechanism, test tube tipping mechanism and test tube acquisition testing mechanism, the setting of test tube acquisition testing mechanism are being held The top of support plate, the loading plate are arranged on test tube tipping mechanism, and the top of loading plate is arranged in the test tube position-limit mechanism, The lower section of the loading plate is equipped with recycling funnel, and the bottom of the recycling funnel is equipped with and its internal reflux line being connected to, institute Test tube acquisition testing mechanism is stated to include portal frame, acquisition component, clasmatosis component, move material platform and move material platform water for driving The dynamic shifting material component of translation, the acquisition component and clasmatosis component are arranged at the top for moving material platform, the portal frame Top is set there are two connecting plate, sets that there are two in horizontally disposed support rod, the shiftings material platform energy between two connecting plates That enough slides is set on two support rods, the top moved material component and portal frame is arranged in.
Further, the clasmatosis component includes sliding shoe, broken motor, lifting cylinder, motor cabinet, sets vertically It sets in the sliding rail for moving the mounting plate of material platform bottom and being arranged on mounting plate side wall, what the sliding shoe can slide is set in institute It states on sliding rail, the motor cabinet is fixed on the side wall of the sliding shoe, and the broken motor is arranged on motor cabinet, described broken Agitating shaft is arranged on the output end of broken motor, it is in the broken blade being staggered, institute that several are arranged on the agitating shaft It states lifting cylinder and the top for moving material platform is set, and be fixedly connected at the top of the output end of lifting cylinder and sliding shoe.
Further, the acquisition component includes infusion pump, monitor station, pusher cylinder, cabinet, the acquisition being vertically arranged The slide bar on mounting plate side wall is managed and is vertically arranged in, the slide bar is equipped with the elevator being slidably matched with it, the acquisition Pipe is fixed on the side wall of elevator by pipe collar, is connected between the collection tube and the input terminal of infusion pump by hose, institute It states and is connected between the output end of infusion pump and monitor station by hose, the inside of the monitor station is equipped with genetic chip, described The top for moving material platform is arranged in pusher cylinder, is fixedly connected at the top of the output end and elevator of the pusher cylinder, the machine Case and monitor station are electrically connected, and the cabinet is equipped with display screen.
Further, the material component that moves includes the peace that shifting material motor and two are separately positioned on two sides at the top of portal frame Seat is filled, is equipped with the installation axle that can be rotated in each mounting base, is arranged with synchronizing wheel in each installation axle, two It is connected between a synchronizing wheel by synchronous belt drive, is fixedly connected at the top of the synchronous belt and shifting material platform, it is described It moves between the output end and one of them described installation axle of material motor and is connected by shaft coupling.
Further, the test tube tipping mechanism includes rotating electric machine, two ring gears and two spaced fixations Vertical plate is equipped with the mounting cylinder being rotatablely connected with it on each fixed board, and the loading plate is fixed on two mounting cylinders Between, fixing seat is equipped between the loading plate and mounting cylinder, two ring gears are separately positioned on the two sides of the bottom of loading plate, described Rotating electric machine is fixed on the side wall of a fixed board, and the rotary shaft that can be rotated is equipped between two fixed boards, It is arranged in the rotary shaft there are two gear is rotated, two rotation gears are meshed with two ring gears respectively, the rotation The output end of motor is fixedly connected with the end of rotary shaft.
Further, the test tube position-limit mechanism includes there are two mounting bar, two symmetrically arranged compression bars and being used for The position for driving two compression bars to move towards adjusts component, and the compression bar is equipped with several limit cambered surfaces, the carrying Plate is equipped with several jacks, and the bottom of each mounting bar is all provided with there are two supporting track, each supporting track Top is equipped with the feed block being slidably matched with it, and the mounting bar is fixed on the top of two feed blocks, each installation Item corresponds to a compression bar, several buffer springs are equipped between the mounting bar and corresponding compression bar, described slow The both ends for rushing spring are connected on the side wall of compression bar and mounting bar.
Further, it includes rack gear, stepper motor and two symmetrically arranged attachment bases that the position, which adjusts component, often It is equipped with the connecting shaft being rotatablely connected with it on a attachment base, drive rod, each peace are arranged in the connecting shaft The two sides of dress item are equipped with the first connecting rod and second connecting rod hinged with mounting bar, the first connecting rod and second connecting rod respectively and The both ends of drive rod are hinged, the top slide cooperation of the rack gear and loading plate, are arranged on the output end of the stepper motor The transmission gear being engaged with rack.
Further, test tube cleaning, drying mechanism includes support bracket and horizontally disposed perfusion tube on the gantry Road, the liquid-transport pipe-line are equipped with several liquid outlet pipes communicated therewith, atomization spray are equipped in each liquid outlet pipe Mouth, the liquid-transport pipe-line are equipped with input duct, and the top of the support bracket is equipped with padded frame, and the top of the padded frame is equipped with The top on inclined-plane, the padded frame is equipped with several air-heaters towards loading plate.
Compared with the prior art, the invention has the beneficial effects that:
One, the present invention are equipped with loading plate, test tube position-limit mechanism, test tube cleaning, drying mechanism, test tube tipping mechanism and test tube and adopt Collect testing agency;Test tube acquisition testing mechanism can carry out clasmatosis operation respectively to each test tube automatically and can be automatic Realization detects each test tube respectively, and test tube cleaning, drying mechanism can realize the cleaning, drying work to each test tube automatically Industry, test tube tipping mechanism can realize the inclination of test tube automatically, invisible spectro cleaning solution enable to pour out, to solve cannot achieve The technical issues of to the crushing operations for detecting and being difficult to realize respectively to cell of multiple test tube inner cell liquid.
Secondly, the present invention clasmatosis work can be carried out to each test tube automatically by test tube acquisition testing mechanism respectively Industry enables cell to release its internal DNA fragmentation, and can realize and be detected respectively to each test tube automatically, makes Worker can be derived that the testing result of each test tube, improve the genetic test efficiency to cell liquid;Lifting cylinder work energy Enough move sliding shoe in the vertical direction, sliding shoe is able to drive motor cabinet and is moved, and is able to drive motor cabinet Broken motor is moved, and broken motor is made to be able to drive the inside that broken blade is moved to test tube, and being crushed motor work can So that agitating shaft is rotated, broken blade is enable to rotate and crushing operation, pusher are carried out to invisible spectro cell liquid Cylinder operation can be such that elevator is gone up and down, and so that elevator is able to drive the inside that collection tube is moved to test tube, in infusion pump Work under invisible spectro cell liquid can be enable to extract out by collection tube, and inspection can be delivered under the action of hose In scaffold tower, genetic chip is made to can be realized the detection operation to cell liquid.
Thirdly, the present invention cleaning, drying operation to each test tube can be realized by test tube cleaning, drying mechanism automatically, It is cleaned manually without worker, brings biggish convenience for worker;It is passed through cleaning solution to the inside of liquid-transport pipe-line, is made The state that cleaning solution can be atomized by atomizer sprays, and cleaning solution is enable to carry out washing and cleaning operation, rotating electric machine to test tube Work can drive rotary shaft to rotate, and so that rotary shaft is able to drive rotation gear and rotate, be able to drive rotation gear Ring gear rotates, and loading plate is made to rotate, so that test tube be made to carry out run-off the straight, invisible spectro cleaning solution is enable to fall Out.
Four, the present invention can realize the rotation of loading plate by test tube tipping mechanism automatically, make the examination at the top of loading plate Pipe can tilt, and invisible spectro cleaning solution is enable to pour out, and air-heater is facilitated to carry out drying operation to test tube, be worker Bring biggish convenience.
Five, the present invention can be realized automatically by test tube position-limit mechanism and different direct test tubes are fixed, thus It realizes and genetic test is carried out to different invisible spectro cell liquid, the fixed structure of test tube is adjusted manually without worker Section, brings great convenience for worker.
Detailed description of the invention
Fig. 1 is schematic perspective view of the invention;
Fig. 2 is positive structure diagram of the invention;
Fig. 3 is partial schematic sectional view one of the invention;
Fig. 4 is enlarged drawing at A in Fig. 3;
Local overlooking schematic diagram Fig. 5 of the invention;
Fig. 6 is partial schematic sectional view two of the invention;
Fig. 7 is enlarged drawing at B in Fig. 6;
Fig. 8 is partial schematic sectional view three of the invention.
Figure label are as follows:
Loading plate 10 recycles funnel 11, reflux line 12, test tube position-limit mechanism 20, mounting bar 21, compression bar 22, limit cambered surface 23, jack 24, supporting track 25, feed block 26, buffer spring 27, position adjusting component 28, rack gear 281, stepper motor 282, Attachment base 283, connecting shaft 284, drive rod 285, first connecting rod 286, second connecting rod 287, transmission gear 288, test tube cleaning are dried Dry mechanism 30, support bracket 31, liquid-transport pipe-line 32, liquid outlet pipe 33, atomizer 34, input duct 35, padded frame 36, air-heater 37, test tube tipping mechanism 40, rotating electric machine 41, ring gear 42, fixed board 43, mounting cylinder 44, fixing seat 45, rotary shaft 46, rotation Rotating disk 47, test tube acquisition testing mechanism 50, portal frame 51 move material platform 52, connecting plate 53, and support rod 54 moves material component 55, moves Expect motor 551, mounting base 552, installation axle 553, synchronizing wheel 554, synchronous belt 555, acquisition component 60, infusion pump 61, detection Platform 62, pusher cylinder 63, cabinet 64, slide bar 65, elevator 66, display screen 67, collection tube 68, clasmatosis component 70, sliding Block 71 is crushed motor 72, lifting cylinder 73, motor cabinet 74, mounting plate 75, sliding rail 76, agitating shaft 77, broken blade 78.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to the accompanying drawings and embodiments, right The present invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, and It is not used in the restriction present invention.
In the description of the present invention, it is to be understood that, term " longitudinal direction ", " transverse direction ", "upper", "lower", "front", "rear", The orientation or positional relationship of the instructions such as "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outside" is based on attached drawing institute The orientation or positional relationship shown is merely for convenience of the description present invention, rather than the device or element of indication or suggestion meaning must There must be specific orientation, be constructed and operated in a specific orientation, therefore be not considered as limiting the invention.
Referring to figs. 1 to Fig. 8 it is found that including loading plate 10, test tube position-limit mechanism 20, test tube cleaning, drying mechanism 30, examination The top of loading plate 10 is arranged in pipe tipping mechanism 40 and test tube acquisition testing mechanism 50, test tube acquisition testing mechanism 50, The loading plate 10 is arranged on test tube tipping mechanism 40, and the top of loading plate 10, institute is arranged in the test tube position-limit mechanism 20 The lower section for stating loading plate 10 is equipped with recycling funnel 11, and the bottom of the recycling funnel 11 is equipped with and its internal reflux line being connected to 12, test tube acquisition testing mechanism 50 includes portal frame 51, acquisition component 60, clasmatosis component 70, moves material 52 and of platform For driving the shifting material component 55 for moving material platform 52 and moving horizontally, the acquisition component 60 and clasmatosis component 70 are arranged at shifting Expect that the top of platform 52, the top of the portal frame 51 are set there are two connecting plate 53, set between two connecting plates 53 there are two In horizontally disposed support rod 54, what the shifting material platform 52 can slide is set on two support rods 54, and component is expected in the shifting 55 are arranged in the top of portal frame 51;It can be realized automatically by test tube position-limit mechanism 20 and different direct test tubes are consolidated It is fixed, genetic test is carried out to different invisible spectro cell liquid to realize, the structure fixed manually to test tube without worker It is adjusted, brings great convenience for worker;It can be automatically to each test tube point by test tube acquisition testing mechanism 50 Not carry out clasmatosis operation, so that cell is released its internal DNA fragmentation, and can realize automatically to each test tube It is detected respectively, worker is made to can be derived that the testing result of each test tube, improve the genetic test efficiency to cell liquid, The cleaning, drying operation to each test tube can be realized automatically by test tube cleaning, drying mechanism 30, carried out manually without worker Cleaning brings biggish convenience for worker, can realize the rotation of loading plate 10 automatically by test tube tipping mechanism 40, make The test tube at the top of loading plate 10 can tilt, and invisible spectro cleaning solution is enable to pour out, and facilitate air-heater 37 to test tube into Row drying operation, brings biggish convenience for worker;Reflux line 12 is convenient to be collected and returns to the cleaning solution fallen Stream.
The clasmatosis component 70 includes sliding shoe 71, broken motor 72, lifting cylinder 73, motor cabinet 74, vertical The sliding rail 76 for moving the mounting plate 75 of material 52 bottom of platform and being arranged on 75 side wall of mounting plate is set, and the sliding shoe 71 can be slided Dynamic is set on the sliding rail 76, and the motor cabinet 74 is fixed on the side wall of the sliding shoe 71, the broken motor 72 It is arranged on motor cabinet 74, agitating shaft 77 is arranged on the output end of the broken motor 72, is arranged on the agitating shaft 77 Several are in the broken blade 78 being staggered, and the top for moving material platform 52, and lifting cylinder 73 is arranged in the lifting cylinder 73 Output end be fixedly connected with the top of sliding shoe 71;The work of lifting cylinder 73 can be such that sliding shoe 71 carries out in the vertical direction Mobile, sliding shoe 71 is able to drive motor cabinet 74 and is moved, so that motor cabinet 74 is able to drive broken motor 72 and moved, made Broken motor 72 is able to drive the inside that broken blade 78 is moved to test tube, and the broken work of motor 72 can be such that agitating shaft 77 occurs Rotation enables broken blade 78 to rotate and carries out crushing operation to invisible spectro cell liquid.
The acquisition component 60 includes infusion pump 61, monitor station 62, pusher cylinder 63, cabinet 64, adopting of being vertically arranged Collector 68 and the slide bar 65 being vertically arranged on 75 side wall of mounting plate, the slide bar 65 are equipped with the elevator being slidably matched with it 66, the collection tube 68 is fixed on the side wall of elevator 66 by pipe collar, the input terminal of the collection tube 68 and infusion pump 61 Between by hose be connected to, be connected between the output end and monitor station 62 of the infusion pump 61 by hose, the monitor station 62 Inside genetic chip is installed, the top for moving material platform 52, the output of the pusher cylinder 63 is arranged in the pusher cylinder 63 End is fixedly connected with the top of elevator 66, and the cabinet 64 is electrically connected with monitor station 62, and the cabinet 64 is equipped with display Screen 67;The work of pusher cylinder 63 can be such that elevator 66 is gone up and down, and so that elevator 66 is able to drive collection tube 68 and be moved to examination The inside of pipe can enable invisible spectro cell liquid extract out by collection tube 68 under the work of infusion pump 61, and soft It can be delivered in monitor station 62 under the action of pipe, genetic chip is made to can be realized the detection operation to cell liquid.
The material component 55 that moves includes the installation that shifting material motor 551 and two are separately positioned on 51 top two sides of portal frame Seat 552 is equipped with the installation axle 553 that can be rotated in each mounting base 552, is arranged in each installation axle 553 There is synchronizing wheel 554, is sequentially connected between two synchronizing wheels 554 by synchronous belt 555, the synchronous belt 555 and shifting The top of material platform 52 is fixedly connected, and passes through connection between the output end and one of them described installation axle 553 for moving material motor 551 The connection of axis device;Moving the material work of motor 551 can make installation axle 553 rotate, and installation axle 553 is made to be able to drive synchronizing wheel 554 It rotates, so that synchronous belt 555 be made to rotate, so that synchronous belt 555 is able to drive shifting material platform 52 and moved, make to move Material platform 52 is able to drive clasmatosis component 70 and acquisition component 60 is moved, and makes clasmatosis component 70 and acquisition component 60 Broken and Collecting operation can be carried out to each invisible spectro cell liquid.
The test tube tipping mechanism 40 includes 41, two ring gears 42 of rotating electric machine and two spaced fixed boards 43, the mounting cylinder 44 being rotatablely connected with it is equipped on each fixed board 43, and the loading plate 10 is fixed on two peaces Between fitted tube 44, fixing seat 45 is equipped between the loading plate 10 and mounting cylinder 44, two ring gears 42 are separately positioned on loading plate 10 two sides of the bottom, the rotating electric machine 41 are fixed on the side wall of a fixed board 43, two fixed boards 43 it Between be equipped with the rotary shaft 46 that can rotate, be arranged that there are two rotate gear 47, two rotation gears in the rotary shaft 46 47 are meshed with two ring gears 42 respectively, and the output end of the rotating electric machine 41 is fixedly connected with the end of rotary shaft 46;Pass through Test tube tipping mechanism 40 can realize the rotation of loading plate 10 automatically, so that the test tube at 10 top of loading plate is tilted, make test tube Interior cleaning solution can be poured out, and air-heater 37 is facilitated to carry out drying operation to test tube, bring biggish side for worker Just, the work of rotating electric machine 41 can drive rotary shaft 46 to rotate, and so that rotary shaft 46 is able to drive rotation gear 47 and rotate, Make rotation gear 47 be able to drive ring gear 42 to rotate, loading plate 10 is made to rotate, so that test tube is made to carry out run-off the straight, Invisible spectro cleaning solution is set to pour out.
The test tube position-limit mechanism 20 includes there are two 21, two symmetrically arranged compression bars 22 of mounting bar and for driving The position that two compression bars 22 move towards adjusts component 28, and the compression bar 22 is equipped with several limit cambered surfaces 23, described Loading plate 10 is equipped with several jacks 24, and the bottom of each mounting bar 21 is all provided with there are two supporting track 25, Mei Gesuo The top for stating supporting track 25 is equipped with the feed block 26 being slidably matched with it, and the mounting bar 21 is fixed on two feed blocks 26 Top, each mounting bar 21 corresponds to a compression bar 22, the mounting bar 21 and corresponding compression bar 22 it Between be equipped with several buffer springs 27, the both ends of the buffer spring 27 are connected to the side wall of compression bar 22 and mounting bar 21 On;It can be realized automatically by test tube position-limit mechanism 20 and different direct test tubes are fixed, to realize to different examinations Cell liquid in pipe carries out genetic test, is adjusted to the fixed structure of test tube without worker, brings manually for worker It greatly facilitates, the work of stepper motor 282 can drive transmission gear 288 to rotate, and be able to drive transmission gear 288 The rack gear 281 engaged is moved, and so that rack gear 281 is able to drive mounting bar 21 and is moved, enables first connecting rod 286 It drives drive rod 285 to be moved, so that drive rod 285 is able to drive second connecting rod 287 and carry out movement to make two mounting bars 21 can move towards, and so that mounting bar 21 is able to drive compression bar 22 and are moved, enable two compression bars 22 to test tube into Row limit operation, buffer spring 27 can play the role of buffering, test tube avoided to damage because excessively clamping.
It includes rack gear 281, stepper motor 282 and two symmetrically arranged attachment bases 283 that the position, which adjusts component 28, It is equipped with the connecting shaft 284 being rotatablely connected with it on each attachment base 283, is arranged with drive rod in the connecting shaft 284 285, the two sides of each mounting bar 21 are equipped with the first connecting rod 286 and second connecting rod 287 hinged with mounting bar 21, described First connecting rod 286 and second connecting rod 287 are hinged with the both ends of drive rod 285 respectively, the top of the rack gear 281 and loading plate 10 It is slidably matched, the transmission gear 288 engaged with rack gear 281 is arranged on the output end of the stepper motor 282;Stepper motor 282 work can drive transmission gear 288 to rotate, and so that transmission gear 288 is able to drive the rack gear 281 engaged and carry out It is mobile, so that rack gear 281 is able to drive mounting bar 21 and moved, so that first connecting rod 286 is able to drive drive rod 285 and moved It is dynamic, so that drive rod 285 is able to drive second connecting rod 287 and carries out movement to make two mounting bars 21 move towards.
Test tube cleaning, drying mechanism 30 includes support bracket 31 and the liquid-transport pipe-line that is horizontally set on portal frame 51 32, the liquid-transport pipe-line 32 is equipped with several liquid outlet pipes 33 communicated therewith, is equipped in each liquid outlet pipe 33 Atomizer 34, the liquid-transport pipe-line 32 are equipped with input duct 35, and the top of the support bracket 31 is equipped with padded frame 36, described The top of padded frame 36 is equipped with inclined-plane, and the top of the padded frame 36 is equipped with several air-heaters 37 towards loading plate 10;Work Author enables state spray of the atomizer 34 by cleaning solution to be atomized by being passed through cleaning solution to the inside of liquid-transport pipe-line 32 Out, cleaning solution is enable to carry out washing and cleaning operation to test tube, test tube tipping mechanism 40 can realize the rotation of loading plate 10 automatically, make The test tube at the top of loading plate 10 can tilt, and invisible spectro cleaning solution is enable to pour out, and facilitate air-heater 37 to test tube into Row drying operation.
The working principle of the invention: test tube is placed on loading plate 10 by worker manually, passes through test tube position-limit mechanism 20 It can realize automatically and different direct test tubes are fixed, gene inspection is carried out to different invisible spectro cell liquid to realize It surveys, the fixed structure of test tube is adjusted manually without worker, is brought great convenience for worker;Stepper motor 282 work can drive transmission gear 288 to rotate, and so that transmission gear 288 is able to drive the rack gear 281 engaged and carry out It is mobile, so that rack gear 281 is able to drive mounting bar 21 and moved, so that first connecting rod 286 is able to drive drive rod 285 and moved It is dynamic, so that drive rod 285 is able to drive second connecting rod 287 and carry out mobile so that two mounting bars 21 be made to move towards, makes to pacify Dress item 21 is able to drive compression bar 22 and is moved, and so that two compression bars 22 is carried out limit operation to test tube, passes through test tube Acquisition testing mechanism 50 can carry out clasmatosis operation to each test tube automatically respectively, and cell is enable to release its inside DNA fragmentation, and can realize automatically and each test tube is detected respectively, so that worker is can be derived that the detection of each test tube As a result, improving the genetic test efficiency to cell liquid, the work of pusher cylinder 63 can be such that elevator 66 is gone up and down, and make to go up and down Block 66 is able to drive the inside that collection tube 68 is moved to test tube, and invisible spectro cell liquid can be enable under the work of infusion pump 61 It is enough extracted out by collection tube 68, and can be delivered in monitor station 62 under the action of hose, can be realized genetic chip Detection operation to cell liquid, the work of lifting cylinder 73 can be such that sliding shoe 71 is moved in the vertical direction, sliding shoe 71 It is able to drive motor cabinet 74 to be moved, so that motor cabinet 74 is able to drive broken motor 72 and moved, enable broken motor 72 The enough inside for driving broken blade 78 to be moved to test tube, the broken work of motor 72 can make agitating shaft 77 rotate, make to be crushed Blade 78 can rotate and carry out crushing operation to invisible spectro cell liquid, can by test tube cleaning, drying mechanism 30 The automatic cleaning, drying operation realized to each test tube, is cleaned manually without worker, is brought for worker biggish It is convenient, it can realize the rotation of loading plate 10 automatically by test tube tipping mechanism 40, the test tube at 10 top of loading plate is enable to incline Tiltedly, so that invisible spectro cleaning solution is poured out, and air-heater 37 is facilitated to carry out drying operation to test tube, brought for worker Biggish convenience;Reflux line 12 is convenient to be collected and flows back to the cleaning solution fallen, and the work of rotating electric machine 41 can drive rotation Shaft 46 rotates, and so that rotary shaft 46 is able to drive rotation gear 47 and rotates, rotation gear 47 is made to be able to drive ring gear 42 rotate, and loading plate 10 is made to rotate, so that test tube be made to carry out run-off the straight, invisible spectro cleaning solution are enable to fall Out.

Claims (8)

1. one kind is based on biotechnology gene assaying device, which is characterized in that include loading plate (10), test tube position-limit mechanism (20), test tube cleaning, drying mechanism (30), test tube tipping mechanism (40) and test tube acquisition testing mechanism (50), the test tube acquisition Testing agency (50) setting is arranged on test tube tipping mechanism (40) in the top of loading plate (10), the loading plate (10), institute Test tube position-limit mechanism (20) setting is stated at the top of loading plate (10), the lower section of the loading plate (10) is equipped with recycling funnel (11), the bottom of recycling funnel (11) is equipped with and its internal reflux line (12) being connected to, the test tube acquisition testing machine Structure (50) includes portal frame (51), acquisition component (60), clasmatosis component (70), moves material platform (52) and move material for driving The shifting material component (55) that platform (52) moves horizontally, the acquisition component (60) and clasmatosis component (70) are arranged at shifting material platform (52) top is set at the top of the portal frame (51) there are two connecting plate (53), is equipped between two connecting plates (53) Two are in horizontally disposed support rod (54), and what shifting material platform (52) can be slided is set on two support rods (54), institute It states and moves material component (55) setting at the top of portal frame (51).
2. according to claim 1 be based on biotechnology gene assaying device, which is characterized in that the clasmatosis group Part (70) includes sliding shoe (71), broken motor (72), lifting cylinder (73), motor cabinet (74), is vertically arranged in shifting material platform (52) mounting plate (75) of bottom and the sliding rail (76) being arranged on mounting plate (75) side wall, the sliding shoe (71) can be slided Be set on the sliding rail (76), the motor cabinet (74) is fixed on the side wall of the sliding shoe (71), the broken electricity Machine (72) is arranged on motor cabinet (74), is arranged with agitating shaft (77), the stirring on the output end of the broken motor (72) It is in the broken blade (78) being staggered that several are arranged on axis (77), and lifting cylinder (73) setting is moving material platform (52) Top, and be fixedly connected at the top of the output end of lifting cylinder (73) and sliding shoe (71).
3. according to claim 2 be based on biotechnology gene assaying device, which is characterized in that the acquisition component (60) include infusion pump (61), monitor station (62), pusher cylinder (63), cabinet (64), the collection tube (68) being vertically arranged and The slide bar (65) being vertically arranged on mounting plate (75) side wall, the slide bar (65) are equipped with the elevator being slidably matched with it (66), the collection tube (68) is fixed on the side wall of elevator (66) by pipe collar, the collection tube (68) and infusion pump (61) it is connected between input terminal by hose, is connected between the output end and monitor station (62) of the infusion pump (61) by hose Logical, the inside of the monitor station (62) is equipped with genetic chip, and pusher cylinder (63) setting is moving the top for expecting platform (52), It is fixedly connected at the top of the output end of the pusher cylinder (63) and elevator (66), the cabinet (64) and monitor station (62) electricity Property connection, the cabinet (64) be equipped with display screen (67).
4. according to claim 1 be based on biotechnology gene assaying device, which is characterized in that component is expected in the shifting (55) include move material motor (551) and two be separately positioned on portal frame (51) top two sides mounting base (552), Mei Gesuo The installation axle (553) that is equipped with and can rotate on mounting base (552) is stated, is arranged with synchronization on each installation axle (553) Take turns (554), be sequentially connected between two synchronizing wheels (554) by synchronous belt (555), the synchronous belt (555) with Move material platform (52) at the top of be fixedly connected, it is described move material motor (551) output end and one of them described installation axle (553) it Between pass through shaft coupling connect.
5. according to claim 1 be based on biotechnology gene assaying device, which is characterized in that the test tube dumping machine Structure (40) includes rotating electric machine (41), two ring gears (42) and two spaced fixed boards (43), each described solid Determine to be equipped with the mounting cylinder (44) being rotatablely connected with it on vertical plate (43), the loading plate (10) is fixed on two mounting cylinders (44) Between, fixing seat (45) are equipped between the loading plate (10) and mounting cylinder (44), two ring gears (42) are separately positioned on carrying The two sides of the bottom of plate (10), the rotating electric machine (41) are fixed on the side wall of a fixed board (43), two fixations It is equipped with the rotary shaft (46) that can be rotated between vertical plate (43), is arranged on the rotary shaft (46) there are two rotation gear (47), Two rotation gears (47) are meshed with two ring gears (42) respectively, the output end and rotary shaft of the rotating electric machine (41) (46) end is fixedly connected.
6. according to claim 1 be based on biotechnology gene assaying device, which is characterized in that the test tube position restrainer Structure (20) includes there are two mounting bar (21), two symmetrically arranged compression bars (22) and being used to drive two compression bar (22) phases Component (28) are adjusted to mobile position, the compression bar (22) is equipped with several limits cambered surface (23), the loading plate (10) several jacks (24) are equipped with, the bottom of each mounting bar (21) is all provided with there are two supporting track (25), each The feed block (26) being slidably matched with it is equipped at the top of the supporting track (25), the mounting bar (21) is fixed on two The top of feed block (26), each mounting bar (21) correspond to a compression bar (22), mounting bar (21) He Yuqi Several buffer springs (27) are equipped between corresponding compression bar (22), the both ends of the buffer spring (27) are connected to pressure On the side wall of tight item (22) and mounting bar (21).
7. according to claim 6 be based on biotechnology gene assaying device, which is characterized in that the position adjusting group Part (28) includes rack gear (281), stepper motor (282) and two symmetrically arranged attachment bases (283), each attachment base (283) it is equipped with the connecting shaft (284) being rotatablely connected with it on, is arranged with drive rod (285) on the connecting shaft (284), often The two sides of a mounting bar (21) are equipped with and mounting bar (21) hinged first connecting rod (286) and second connecting rod (287), institute It states first connecting rod (286) and second connecting rod (287) is hinged with the both ends of drive rod (285) respectively, the rack gear (281) and carrying The top slide of plate (10) cooperates, and is arranged with the driving cog engaged with rack gear (281) on the output end of the stepper motor (282) It takes turns (288).
8. according to claim 1 be based on biotechnology gene assaying device, which is characterized in that the test tube cleaning is dried Dry mechanism (30) include support bracket (31) and the liquid-transport pipe-line (32) being horizontally set on portal frame (51), the liquid-transport pipe-line (32) several liquid outlet pipes (33) communicated therewith are equipped with, are equipped with atomizer on each liquid outlet pipe (33) (34), the liquid-transport pipe-line (32) is equipped with input duct (35), and the top of the support bracket (31) is equipped with padded frame (36), institute The top for stating padded frame (36) is equipped with inclined-plane, and the top of the padded frame (36) is equipped with several hot winds towards loading plate (10) Machine (37).
CN201910656893.8A 2019-07-19 2019-07-19 One kind being based on biotechnology gene assaying device Withdrawn CN110305783A (en)

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Application Number Priority Date Filing Date Title
CN201910656893.8A CN110305783A (en) 2019-07-19 2019-07-19 One kind being based on biotechnology gene assaying device

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Application Number Priority Date Filing Date Title
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111298987A (en) * 2020-02-24 2020-06-19 安徽环球基因科技有限公司 Biological cell separation device
CN112415147A (en) * 2020-12-01 2021-02-26 李婷婷 Method for detecting content of heavy metal in aquatic product
CN113249207A (en) * 2021-06-17 2021-08-13 姚杰 Gene detection system and method integrating extraction and detection
CN114545015A (en) * 2022-04-27 2022-05-27 潍坊市检验检测中心 Liquid transfer device for food detection
CN116448748A (en) * 2023-06-08 2023-07-18 泉州泉港高梦五金有限公司 Food heavy metal detector

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111298987A (en) * 2020-02-24 2020-06-19 安徽环球基因科技有限公司 Biological cell separation device
CN112415147A (en) * 2020-12-01 2021-02-26 李婷婷 Method for detecting content of heavy metal in aquatic product
CN113249207A (en) * 2021-06-17 2021-08-13 姚杰 Gene detection system and method integrating extraction and detection
CN114545015A (en) * 2022-04-27 2022-05-27 潍坊市检验检测中心 Liquid transfer device for food detection
CN116448748A (en) * 2023-06-08 2023-07-18 泉州泉港高梦五金有限公司 Food heavy metal detector
CN116448748B (en) * 2023-06-08 2024-03-26 台山市佳和食品有限公司 Food heavy metal detector

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