CN110279788A - A kind of preparation process of Chinese medicine element cream - Google Patents

A kind of preparation process of Chinese medicine element cream Download PDF

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Publication number
CN110279788A
CN110279788A CN201910627778.8A CN201910627778A CN110279788A CN 110279788 A CN110279788 A CN 110279788A CN 201910627778 A CN201910627778 A CN 201910627778A CN 110279788 A CN110279788 A CN 110279788A
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auxiliary material
chinese medicine
preparation process
cream
medicine element
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蔡星兴
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Zhejiang Zuo Libaicao Prepared Slices Of Chinese Crude Drugs Co Ltd
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Zhejiang Zuo Libaicao Prepared Slices Of Chinese Crude Drugs Co Ltd
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Priority to CN201910627778.8A priority Critical patent/CN110279788A/en
Publication of CN110279788A publication Critical patent/CN110279788A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/52Juglandaceae (Walnut family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

A kind of preparation process of Chinese medicine element cream, preparation step include: the processing of (1) major ingredient: be soaked in water Chinese medicine, is decocted after immersion, obtained decoction liquor sieving, is precipitated, the supernatant after taking precipitating after merging decoction liquor and filtered fluid I, sieving, resulting filtered fluid II is concentrated spare;Auxiliary material processing: selecting auxiliary material to be smashed and ground, and is sieved, and auxiliary material paste is obtained after being mixed with water;Receive cream: will be cooling after obtained concentrate and auxiliary material paste Hybrid Heating stirring, obtain plain cream;This programme design working efficiency with traditional approach compared with greatly improves, and obtained lotion is finer and smoother, changes that preparation process is complicated, Production Time is long, working efficiency is low, the optional problem that auxiliary material is few, lotion is coarse.

Description

A kind of preparation process of Chinese medicine element cream
Technical field
The invention belongs to form of Chinese drug preparation technical fields, it particularly relates to a kind of preparation process of Chinese medicine element cream.
Background technique
Traditional Chinese medicine cream wetting drug is divided into: " meat or fish cream, plain cream, clear cream, honey ointment ", is one of Chinese medicine conventional dosage forms, with a long history, It can be rated as the rarity of traditional Chinese medicine, collection monarch minister, helps, makes, the great achievement of science, method, prescription, drugs, and cream wetting drug is it is emphasised that " sincerely examine yin-yang place And it is adjusted, and scheduled to last with flat ", help its biochemistry, its multiple balance.Wherein plain cream is primarily adapted for use in child, women and spleen and stomach function and weakens, Indigestion and the patient that should not use glue class, and can substantially reduce the cost.
The production of traditional plain cream is mainly one pot of one side of a people, and generally with lotus seeds, jujube endures mud as auxiliary material, and with rock sugar, Honey, the flavoring agents such as maltose;Its preparation process is complicated, and manufacturing technology requires height, and the operating time is long, generally first impregnate medicine, Secondary rear merging filtrate is decocted, natural sedimentation 6 hours, lotus seeds or jujube are separately impregnated into half an hour, is then put into pot and decocts 2h, To be cooled, lotus seeds directly mash into mud, and jujube need to remove the peel and core, then mashes into mud, for use;But time-consuming, auxiliary material processing needs 3h or more is wanted, working efficiency is lower, and available auxiliary material is also less, and the cream taste prepared is more coarse, and mouthfeel is bad.
Sesame: it is sweet in flavor, it is mild-natured, through liver, kidney, large intestine channel, there are nourishing liver and kidney, benefiting essence-blood, the dry effect of ease constipation is Chinese medicine help Yin tonics in medicine is the common medicine in herbal paste production, can be too high due to its fat content, can not be ground into fine powder, and is only had Decoction is removed slag, and medicinal material is wasted;Walnut kernel: it is sweet in flavor and warm in property, have the effect of tonifying kidney and strengthening yang, astringing lung for relieving asthma, relax bowel and defecation, be in build up one's health by taking tonic It is partial to the medicine of yang-tonifying in beneficial medicine, is also commonly used in herbal paste production, can not be equally ground into thin since fatty oil content is up to 58% Powder and can only be removed slag with decoction, the utilization rate of drug is not high.
The file of Publication No. CN105614798A discloses a kind of queen bee melanin cream, by formula do black ant, what The crushing such as the tuber of multiflower knotweed, walnut kernel, Semen sesami nigrum, big semen sojae atricolor, black rice are fine powder, stir evenly, add the bee of total weight three to four-fold Honey mixes to obtain the final product, and the auxiliary materials such as the fleece-flower root, walnut kernel, Semen sesami nigrum contain compared with many greases of sauce, moisture, simple pulverization process in the program The problems such as obtained particle is uneven, easy to reunite, and plain cream finished product can be made to be unevenly distributed;And obtained plain cream mouthfeel it is bad, Active constituent content is lower.
Summary of the invention
In view of the above problems, the present invention provides a kind of innovation of Chinese medicine element cream and preparation process, can solve traditional plain Time-consuming in cream preparation process, working efficiency is low, auxiliary material selects less, availability is low, lotion is coarse, is unfavorable for asking for absorption of human body Topic.
Technical scheme is as follows: a kind of innovation of Chinese medicine element cream and preparation process, preparation step are as follows:
Major ingredient processing: (1) it by solid-liquid ratio for the ratio of 1:6 ~ 1:10 is soaked in water Chinese medicine, is decocted, obtained after immersion Decoction liquor filtering, is precipitated after obtaining filtered fluid I;(2) supernatant after taking precipitating crosses 80 ~ 100 meshes, by resulting mistake Filtrate II is concentrated, and it is spare to obtain concentrate a;
Auxiliary material processing: (1) after selecting one of jujube, lotus seeds, sesame, walnut or a variety of, broken wall to crush, crossing 40 ~ 60 meshes, It is spare that auxiliary material paste b is obtained after being mixed with water;Or one of selection jujube, lotus seeds, sesame, walnut or a variety of, directly It is mixed with water and carries out the broken processing of wall cell disruption powder;
Receive cream: will be cooling after obtained concentrate a and auxiliary material paste b Hybrid Heating stirring, obtain plain cream.
In this programme design, Chinese medicine immersion soaks moisture sufficiently inside medicinal material, and Chinese medicine is made to reach inside and outside Dynamic equilibrium is conducive to discharge the effective ingredient of Chinese medicine sufficiently.
Preferably, the decocting process include it is first decoct and secondary decoction, the time decocted for the first time is 55 ~ 70min, two The time of secondary decoction is 40 ~ 50min;Further, decocting process are as follows: intense fire quickly boils, and mild fire is stewed slowly, does not need for a long time Intense fire bumping does not need very big evaporation capacity in decoction process, to control its evaporation capacity instead, just decocts two and decocts the same, boiling After turn mild fire and stew slowly.
In this programme design, first decoct makes medical fluid boil so that effective component sufficiently flows out in decoction, secondary decoction When the duration and degree of heating is turned down, flow out effective component slowly sufficiently, obtained decoction purity is high, effect are good.
Further, the volume of the concentrate a is the 1/5 ~ 1/3 of II volume of filtered fluid.
Further, the condition of the crushing are as follows: > 38000r/min, 8 ~ 12min.
In this programme design, high speed pulverization process can effectively be crushed the plant cell wall construction of auxiliary material, by of auxiliary material Grain becomes extremely tiny, is conducive to mix with the full and uniform of concentrated medicine juice, effective component is easier to dissolve out, obtained lotion mouthfeel It is finer and smoother.
Further, the solid-liquid ratio of auxiliary material and water is 1:1.0 ~ 1.5 in the auxiliary material processing.
In this programme design, the ratio of auxiliary material and water directly affects the broken ratio of auxiliary material, auxiliary by multiple repetition test The ratio of material and water is optimum range in 1:1.0 ~ 1.5, and for the sporoderm-broken rate of auxiliary material up to 80% or more, effect is best within this range.
Further, flavoring agent and concentrate a are added in the receipts cream step, is added after flavoring agent sufficiently dissolves auxiliary Material paste b is mixed evenly, and the flavoring agent is one or more use of the intensity edibles agent such as maltose, rock sugar, xylitol, sucrose In the mouthfeel for improving plain cream.
Further, it is 4 ~ 10 hours that water, which impregnates the soaking time of Chinese medicine, in the major ingredient processing.
In this programme design, auxiliary material paste first with after warm water stirring and dissolving, can play the effect mixed well, and be conducive to it uniformly Be dispersed in concentrated medicine juice.
Compared with prior art, the present invention have it is following the utility model has the advantages that
The technology mode used in this programme design working efficiency compared with traditional approach greatly improves, and obtained lotion is more Exquisiteness, changes that preparation process is complicated, Production Time is long, working efficiency is low, the problem that auxiliary material is few, lotion is coarse can be selected.
Specific embodiment
Preparing embodiment and test example below uses the cream of the present inventor to grow prescription, which is not limited to this Prescription, the prescription form by weight are as follows: 120 parts of ramulus cinnamomi, 150 parts of stir-baked MASSA FERMENTATA MEDICI-NALIS, fries 60 parts of dried orange peel, stir-baked RADIX PAEONIAE ALBA at 120 parts of Radix Astragali 240 parts, 120 parts of Radix Glycyrrhizae, 120 parts of dark plum, 120 parts of stir-baked FLOS SOPHORAE IMMATURUS, 120 parts of rhizoma dioscoreae nipponicae, 90 parts of Radix Angelicae Sinensis, 90 parts of radix saposhnikoviae, raw Rhizoma Atractylodis Macrocephalae 120 Part, 200 parts of lotus seeds mud (or 200 parts of big jujube paste or 120 parts of Semen sesami nigrum mud, 120 parts of walnut kernel mud).
Embodiment 1
A kind of innovation of Chinese medicine element cream and preparation process, preparation step are as follows:
Major ingredient processing: (1) it in ratio purified water that solid-liquid ratio be 1:8 impregnates Chinese medicine formula in, is put into after impregnating 4 hours In boiling machine, mild fire is switched to after first boiling with high heat, head juice decocts 1 hour (boiling time is included), squeezes pack, filtering Decoction retains filtrate I and the dregs of a decoction, is added the secondary decoction of pure water progress in the obtained dregs of a decoction in the ratio that solid-liquid ratio is 1:7, and two Juice decocts 45 minutes, squeezes pack, obtains filtrate II, carries out natural sedimentation, sedimentation time 4 after merging filtrate I and filtrate II Hour;(2) supernatant after taking precipitating crosses 80 meshes, resulting filtered fluid III is transferred in heating kettle and carries out heating concentration, Offscum is skimmed in concentration process, the control duration and degree of heating prevents bumping or dryouies, and when obtaining 1/3 that concentrate a is filtered fluid III, stops adding Heat is taken out spare;
Auxiliary material processing: (1) jujube is clay standby: choosing jujube by formula rate, jujube and purified water are pressed the ratio of 1:1.2 by stoning Example is added into cooking wall-breaking machine and crushes, and crushes its complete broken wall, in the pasty state, crosses 60 meshes, spare;(2) sesame, walnut dew Preparation: choosing sesame, walnut by formula rate, and sesame, walnut and purified water are added in the ratio of 1:1.5 to cooking wall-breaking machine Middle crushing crushes its complete broken wall, in the pasty state, crosses 60 meshes, spare;
It receives cream: concentrate a is poured into copper pot, 150 parts of rock sugar, 100 parts of maltose is added wait be completely dissolved, big jujube paste, sesame is added Paste and walnut kernel paste, are stirred continuously, and pay close attention to boiling situation, prevent from overflowing, and vesicle becomes larger bubble, turn over fish maw and steep, lift stirring Stick is shown in that lotion hangs flag, takes the dish out of the pot rapidly, lotion is poured into cut-and-dried sterilized, clean heatproof container, to completely cooling Afterwards, it covers;Or the inner wrapping of 20 grams/packet is bundled into packing machine while hot.
The preparation of big jujube paste in this programme in auxiliary material processing, using " beautiful MJ-BL10K21 type " broken wall cooking machine, 38000r/min, 10min, sporoderm-broken rate improve the mode for enduring mud in traditional handicraft up to 80% or more, increase the same of efficiency When improve the bioavilability of big jujube paste.
Sesame, walnut dew preparation in this programme in auxiliary material processing, using " beautiful MJ-BL10K21 type " broken wall cooking machine, 38000r/min, 10min, this law use high speed broken wall cooking machine, the sporoderm-broken rate for the auxiliary material for keeping the fat contents such as sesame, walnut dew high Up to 80% or more, improves to decoct to remove slag in traditional handicraft and receive the mode of cream, the high speed rotation through eight knives can effectively destroy sesame Numb, walnut kernel cell wall, discharges intracellular grease, is formed and is stablized, and fine and smooth oil water mixture substantially increases biological utilisation Degree, while having saved medicinal material.
Such as attached drawing 1 ~ 2, jujube is observed with the clamor 107JPC precision measuring microscope an of factory (Shanghai) production of Shanghai optics instrument Broken wall situation before and after broken wall: before attached drawing 1 is broken wall, after attached drawing 2 is broken wall, by comparing it is found that after using high speed broken wall treatment Jujube sporoderm-broken rate it is high, and then know that the ingredient of jujube has obtained sufficient release.
Embodiment 2
A kind of innovation of Chinese medicine element cream and preparation process, preparation step are as follows:
Major ingredient processing: (1) it in ratio purified water that solid-liquid ratio be 1:6 impregnates Chinese medicine formula in, is put into after impregnating 4 hours In boiling machine, mild fire is switched to after first boiling with high heat, head juice decocts 55 minutes (boiling time is included), squeezes pack, mistake Decoction is filtered, filtrate I and the dregs of a decoction are retained, pure water is added in the obtained dregs of a decoction in the ratio that solid-liquid ratio is 1:7 and carries out secondary decoction, Two juice decoct 40 minutes, squeeze pack, obtain filtrate II, carry out natural sedimentation after merging filtrate I and filtrate II, and the sedimentation time is 4 hours;(2) take precipitating after supernatant, cross 80 meshes, resulting filtered fluid III is transferred in heating kettle heat it is dense It contracts, offscum is skimmed in concentration process, the control duration and degree of heating prevents bumping or dryouies, and when obtaining 1/5 that concentrate a is filtered fluid III, stops It only heats, takes out spare;
Auxiliary material processing: (1) jujube is clay standby: choosing jujube by formula rate, jujube and purified water are pressed the ratio of 1:1.2 by stoning Example is added into cooking wall-breaking machine and crushes, and crushes its complete broken wall, in the pasty state, crosses 60 meshes, spare;
(2) lotus seeds are clay standby: broken wall crushes by the way of impacting type cryogenic ultramicro pulverization, mixes well with purified water spare;(3) it presses Formula rate chooses sesame, walnut, and sesame, walnut and purified water are added in the ratio of 1:1.5 into cooking wall-breaking machine and crushed, Its complete broken wall is crushed, in the pasty state, crosses 60 meshes, it is spare;
Receive cream: concentrate a being poured into copper pot, is added 150 parts of rock sugar, wait be completely dissolved, be added big jujube paste, lotus seeds mud, sesame cream, Walnut kernel paste, is stirred continuously, and pays close attention to boiling situation, prevents from overflowing, and vesicle becomes larger bubble, turns over fish maw and steeps, lifts stirring rod and see Lotion hangs flag, takes the dish out of the pot rapidly, lotion is poured into cut-and-dried sterilized, clean heatproof container, after cooling down completely, adds Lid;Or the inner wrapping of 20 grams/packet is bundled into packing machine while hot.
Lotus seeds in this programme in auxiliary material processing are clay standby, using " three clear easily occasion SQW-100D types " wall-broken grinder, break Material size makes the sporoderm-broken rate of lotus seeds 90% or more at 15 ~ 20 microns after broken.
Jujube in this programme in auxiliary material processing is clay standby, using " beautiful MJ-BL10K21 type " broken wall cooking machine, 38000r/min, 12min, sporoderm-broken rate is up to 80% or more.
Sesame, walnut dew preparation in this programme in auxiliary material processing, using " beautiful MJ-BL10K21 type " broken wall cooking machine, 38000r/min, 10min.
Embodiment 3
A kind of innovation of Chinese medicine element cream and preparation process, preparation step are as follows:
Major ingredient processing: (1) it in ratio purified water that solid-liquid ratio be 1:10 impregnates Chinese medicine formula in, is thrown after impregnating 5 hours Entering in boiling machine, mild fire is switched to after first boiling with high heat, head juice decocts 70 minutes (boiling time is included), pack is squeezed, Decoction is filtered, filtrate I and the dregs of a decoction are retained, pure water is added in the obtained dregs of a decoction in the ratio that solid-liquid ratio is 1:8 and carries out secondary decoct It boils, two juice decoct 50 minutes, squeeze pack, filter decoction, obtain filtrate II, and it is heavy to carry out nature after merging filtrate I and filtrate II It forms sediment, the sedimentation time is 5 hours;(2) supernatant after taking precipitating, sieves with 100 mesh sieve, resulting filtered fluid III is transferred to heating kettle Heating concentration is inside carried out, offscum is skimmed in concentration process, the control duration and degree of heating prevents bumping or dryouies, and obtaining concentrate a is filtered fluid III 1/4 when, stop heating, take out it is spare;
Auxiliary material processing: (1) jujube is clay standby: choosing jujube by formula rate, jujube and purified water are pressed the ratio of 1:1.2 by stoning Example is added into cooking wall-breaking machine and crushes, and crushes its complete broken wall, in the pasty state, crosses 60 meshes, spare;(2) sesame cream, walnut It pastes standby: choosing sesame, walnut by formula rate, sesame, walnut and purified water are added in the ratio of 1:1.5 to cooking broken wall It is crushed in machine, crushes its complete broken wall, in the pasty state, cross 60 meshes, it is spare;
It receives cream: concentrate a is poured into copper pot, 100 parts of maltose, 150 parts of sucrose is added wait be completely dissolved, big jujube paste, sesame is added Paste and walnut kernel paste, are stirred continuously, and pay close attention to boiling situation, prevent from overflowing, and vesicle becomes larger bubble, turn over fish maw and steep, lift stirring Stick is shown in that lotion hangs flag, takes the dish out of the pot rapidly, lotion is poured into cut-and-dried sterilized, clean heatproof container, to completely cooling Afterwards, it covers;Or the inner wrapping of 20 grams/packet is bundled into packing machine while hot.
Jujube in this programme in auxiliary material processing is clay standby, using " beautiful MJ-BL10K21 type " broken wall cooking machine, 39000r/min, 12min, sporoderm-broken rate is up to 80% or more.
Sesame cream, walnut dew preparation in this programme in auxiliary material processing, are arranged using " beautiful MJ-BL10K21 type " broken wall Machine, 40000r/min, 8min.
Embodiment 4
A kind of innovation of Chinese medicine element cream and preparation process, preparation step are as follows:
Major ingredient processing: (1) it in ratio purified water that solid-liquid ratio be 1:10 impregnates Chinese medicine formula in, is thrown after impregnating 5 hours Entering in boiling machine, mild fire is switched to after first boiling with high heat, head juice decocts 70 minutes (boiling time is included), pack is squeezed, Decoction is filtered, filtrate I and the dregs of a decoction are retained, pure water is added in the obtained dregs of a decoction in the ratio that solid-liquid ratio is 1:8 and carries out secondary decoct It boils, two juice decoct 50 minutes, squeeze pack, filter decoction, obtain filtrate II, and it is heavy to carry out nature after merging filtrate I and filtrate II It forms sediment, the sedimentation time is 5 hours;(2) supernatant after taking precipitating, sieves with 100 mesh sieve, resulting filtered fluid III is transferred to heating kettle Heating concentration is inside carried out, offscum is skimmed in concentration process, the control duration and degree of heating prevents bumping or dryouies, and obtaining concentrate a is filtered fluid III 1/4 when, stop heating, take out it is spare;
Auxiliary material processing: (1) lotus seeds are clay standby: broken wall crushes by the way of impacting type cryogenic ultramicro pulverization, mixes well with purified water It is spare;(2) sesame, walnut dew preparation: sesame, walnut are chosen by formula rate, by sesame, walnut and purified water by 1:1.5's Ratio is added into cooking wall-breaking machine and crushes, and crushes its complete broken wall, in the pasty state, crosses 60 meshes, spare;
It receives cream: concentrate a being poured into copper pot, 100 parts of rock sugar, 100 parts of maltose is added, wait be completely dissolved, lotus seeds mud, sesame is added Paste and walnut kernel paste, are stirred continuously, and pay close attention to boiling situation, prevent from overflowing, and vesicle becomes larger bubble, turn over fish maw and steep, lift stirring Stick is shown in that lotion hangs flag, takes the dish out of the pot rapidly, lotion is poured into cut-and-dried sterilized, clean heatproof container, to completely cooling Afterwards, it covers;Or the inner wrapping of 20 grams/packet is bundled into packing machine while hot.
Lotus seeds in this programme in auxiliary material processing are clay standby, using " three clear easily occasion SQW-100D types " wall-broken grinder, break Material size makes the sporoderm-broken rate of lotus seeds 90% or more at 15 ~ 20 microns after broken.
Sesame cream, walnut dew preparation in this programme in auxiliary material processing, are arranged using " beautiful MJ-BL10K21 type " broken wall Machine, 39000r/min, 12min.
Comparative example 1 is set, and difference from Example 4 is, does not add auxiliary material;Comparative example 2 is set, not with embodiment 4 It is with place, using traditional pulverization process;Comparative example 3 is set, and for the plain cream sold in the market, testing result is as follows:
As shown above, plain cream lotion prepared by the present invention is fine and smooth, will not be layered, mellow in taste and sweet tea, the more conducively suction of human body The plain cream product of receipts.
Specific embodiment described herein is only an example for the spirit of the invention.The neck of technology belonging to the present invention The technical staff in domain can make various modifications or additions to the described embodiments or replace by a similar method In generation, however, it does not deviate from the spirit of the invention or beyond the scope of the appended claims.

Claims (9)

1. a kind of preparation process of Chinese medicine element cream, preparation step are as follows:
Major ingredient processing: (1) it by solid-liquid ratio for the ratio of 1:6 ~ 1:10 is soaked in water Chinese medicine, is decocted, obtained after immersion Decoction liquor filtering, is precipitated after obtaining filtered fluid I;(2) supernatant after taking precipitating crosses 80 ~ 100 meshes, by resulting mistake Filtrate II is concentrated, and it is spare to obtain concentrate a;
Auxiliary material processing: (1) one of jujube, lotus seeds, sesame, walnut or a variety of are selected, 40 ~ 60 meshes are smashed it through, with water It is spare that auxiliary material paste b is obtained after mixing;
Receive cream: will be cooling after obtained concentrate a and auxiliary material paste b Hybrid Heating stirring, obtain plain cream.
2. a kind of preparation process of Chinese medicine element cream according to claim 1, which is characterized in that the decocting process includes just Secondary decoction and secondary decoction, the time decocted for the first time are 55 ~ 70min, and the time of secondary decoction is 40 ~ 50min.
3. a kind of preparation process of Chinese medicine element cream according to claim 1, which is characterized in that the volume of the concentrate a It is the 1/5 ~ 1/3 of II volume of filtered fluid.
4. a kind of preparation process of Chinese medicine element cream according to claim 1, which is characterized in that crushed in the auxiliary material processing Condition are as follows: be greater than 38000r/min, 8 ~ 12min.
5. a kind of preparation process of Chinese medicine element cream according to claim 1, which is characterized in that auxiliary material in the auxiliary material processing Solid-liquid ratio with water is 1:1.0 ~ 1.5.
6. a kind of preparation process of Chinese medicine element cream according to claim 1, which is characterized in that be added in the receipts cream step Flavoring agent and concentrate a, auxiliary material paste b are mixed, and the flavoring agent is one of maltose, rock sugar, xylitol, sucrose or more Kind.
7. a kind of preparation process of Chinese medicine element cream according to claim 1, which is characterized in that water logging in the major ingredient processing The soaking time for steeping Chinese medicine is 4 ~ 10 hours.
8. a kind of preparation process of Chinese medicine element cream according to claim 1, which is characterized in that big in the auxiliary material processing Jujube, sesame, walnut are all made of " beautiful MJ-BL10K21 type " broken wall cooking machine and carry out broken wall crushing.
9. a kind of preparation process of Chinese medicine element cream according to claim 1, which is characterized in that lotus seeds in the auxiliary material processing Broken wall crushing is carried out using " three clear easily occasion SQW-100D types " wall-broken grinder.
CN201910627778.8A 2019-07-12 2019-07-12 A kind of preparation process of Chinese medicine element cream Pending CN110279788A (en)

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Application publication date: 20190927