CN110261379B - 用于确定体液中的分析物的浓度的方法和设备 - Google Patents

用于确定体液中的分析物的浓度的方法和设备 Download PDF

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Publication number
CN110261379B
CN110261379B CN201910384611.3A CN201910384611A CN110261379B CN 110261379 B CN110261379 B CN 110261379B CN 201910384611 A CN201910384611 A CN 201910384611A CN 110261379 B CN110261379 B CN 110261379B
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China
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detector
light source
test carrier
error detection
demodulated
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Chinese (zh)
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CN110261379A (zh
Inventor
G.阿尔布雷希特
E.鲍曼
M.根特纳-里格勒
S.卡尔夫拉姆
C.尼斯波雷克
K-O.施文克
M.泽尔
F.韦霍夫斯基
K.韦滕格尔
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/42—Absorption spectrometry; Double beam spectrometry; Flicker spectrometry; Reflection spectrometry
    • G01J3/433—Modulation spectrometry; Derivative spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274—Calibration, base line adjustment, drift correction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers
    • G01N2201/0612—Laser diodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G01N2201/0621—Supply
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/069—Supply of sources
    • G01N2201/0696—Pulsed
    • G01N2201/0697—Pulsed lasers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Plasma & Fusion (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201910384611.3A 2013-11-28 2014-11-27 用于确定体液中的分析物的浓度的方法和设备 Active CN110261379B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13194791.3 2013-11-28
EP13194791 2013-11-28
CN201480065071.8A CN105992945A (zh) 2013-11-28 2014-11-27 用于确定体液中的分析物的浓度的方法和设备

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CN110261379A CN110261379A (zh) 2019-09-20
CN110261379B true CN110261379B (zh) 2021-11-12

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CN201480065071.8A Pending CN105992945A (zh) 2013-11-28 2014-11-27 用于确定体液中的分析物的浓度的方法和设备

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Country Link
US (1) US10274430B2 (enExample)
EP (1) EP3074758B1 (enExample)
JP (2) JP6659541B2 (enExample)
KR (1) KR102245011B1 (enExample)
CN (2) CN110261379B (enExample)
CA (1) CA2926287C (enExample)
WO (1) WO2015078954A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3591385A1 (en) 2018-07-06 2020-01-08 Roche Diabetes Care GmbH A detection method for detecting an analyte in a sample
WO2020152510A1 (en) * 2019-01-25 2020-07-30 Matai Laxman Hemoglobin analyzer
US20240094134A1 (en) * 2021-01-13 2024-03-21 Hitachi High-Tech Corporation Automatic analyzer and automatic analysis method
CN113655011B (zh) * 2021-10-20 2022-02-08 武汉新烽光电股份有限公司 一种微流控检测系统及其检测方法

Citations (6)

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CN1937956A (zh) * 2004-05-06 2007-03-28 日本电信电话株式会社 成分浓度测定装置和成分浓度测定装置控制方法
CN101002082A (zh) * 2004-07-27 2007-07-18 帕瑞萨森思公司 用于测量由样本在光信号中引起的相位偏移的方法和设备
EP1912058A1 (de) * 2006-10-14 2008-04-16 Roche Diagnostics GmbH Anordnung und Verfahren zum Erfassen und Auswerten optischer Signale
WO2008155723A1 (en) * 2007-06-21 2008-12-24 Koninklijke Philips Electronics N. V. Microelectronic sensor device with light source and light detector
CN101813618A (zh) * 2010-01-07 2010-08-25 中国科学院半导体研究所 基于光声效应的多种气体同时检测装置及检测方法
CN102482702A (zh) * 2009-04-15 2012-05-30 瑞莱诊断体系股份有限公司 诊断装置和相关方法

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DE2934190A1 (de) * 1979-08-23 1981-03-19 Müller, Gerhard, Prof. Dr.-Ing., 7080 Aalen Verfahren und vorrichtung zur molekuelspektroskopie, insbesondere zur bestimmung von stoffwechselprodukten
JP3046610B2 (ja) * 1990-04-24 2000-05-29 松下電工株式会社 粉塵検出装置
DE4041905A1 (de) * 1990-12-27 1992-07-02 Boehringer Mannheim Gmbh Testtraeger-analysesystem
US5526120A (en) * 1994-09-08 1996-06-11 Lifescan, Inc. Test strip with an asymmetrical end insuring correct insertion for measuring
IL121279A (en) * 1996-07-16 2001-05-20 Roche Diagnostics Gmbh An analytical system with means for testing samples with too small volumes
DE19706520A1 (de) * 1997-02-19 1998-08-20 Lre Technology Partner Gmbh Meßgerät zur Bestimmung der Konzentration mindestens einer Substanz in einer Körperflüssigkeit, insbesondere Blutzuckermeßgerät
CN1131425C (zh) 1997-10-31 2003-12-17 技术化学品及产品股份有限公司 反射计
DE10061336A1 (de) * 2000-12-08 2002-06-13 Roche Diagnostics Gmbh System zur Analyse von Probeflüssigkeiten beinhaltend eine Lagekontrolleinheit
CA2366802A1 (en) * 2001-01-17 2002-07-17 Bayer Corporation Method and apparatus for using infrared readings to detect misidentification of a diagnostic test strip in a reflectance spectrometer
US20030169426A1 (en) * 2002-03-08 2003-09-11 Peterson Timothy A. Test member orientation
US20080119421A1 (en) * 2003-10-31 2008-05-22 Jack Tuszynski Process for treating a biological organism
EP1801568A1 (de) * 2005-12-21 2007-06-27 Micronas Holding GmbH Teststreifen und Verfahren zum Messen einer Analytkonzentration in einer Probe eines biologischen Fluids
EP2362207A1 (de) * 2010-01-28 2011-08-31 F. Hoffmann-La Roche AG Messsystem und Messverfahren insbesondere zur Blutzuckerbestimmung
ITMI20101730A1 (it) * 2010-09-23 2012-03-24 Fond Italiana Fegato Onlus Sistema di tipo "point of care" di misura della bilirubina totale nel plasma, in particolare di neonati
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Publication number Priority date Publication date Assignee Title
CN1937956A (zh) * 2004-05-06 2007-03-28 日本电信电话株式会社 成分浓度测定装置和成分浓度测定装置控制方法
CN101002082A (zh) * 2004-07-27 2007-07-18 帕瑞萨森思公司 用于测量由样本在光信号中引起的相位偏移的方法和设备
EP1912058A1 (de) * 2006-10-14 2008-04-16 Roche Diagnostics GmbH Anordnung und Verfahren zum Erfassen und Auswerten optischer Signale
WO2008155723A1 (en) * 2007-06-21 2008-12-24 Koninklijke Philips Electronics N. V. Microelectronic sensor device with light source and light detector
CN102482702A (zh) * 2009-04-15 2012-05-30 瑞莱诊断体系股份有限公司 诊断装置和相关方法
CN101813618A (zh) * 2010-01-07 2010-08-25 中国科学院半导体研究所 基于光声效应的多种气体同时检测装置及检测方法

Also Published As

Publication number Publication date
KR20160091897A (ko) 2016-08-03
CN110261379A (zh) 2019-09-20
EP3074758B1 (en) 2019-02-27
CA2926287C (en) 2020-03-24
US20160245755A1 (en) 2016-08-25
JP2020024219A (ja) 2020-02-13
JP6659541B2 (ja) 2020-03-04
US10274430B2 (en) 2019-04-30
KR102245011B1 (ko) 2021-04-27
CA2926287A1 (en) 2015-06-04
WO2015078954A1 (en) 2015-06-04
JP2017501395A (ja) 2017-01-12
CN105992945A (zh) 2016-10-05
EP3074758A1 (en) 2016-10-05

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