CA2926287C - Method and device for determining a concentration of an analyte in a bodily fluid - Google Patents

Method and device for determining a concentration of an analyte in a bodily fluid Download PDF

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Publication number
CA2926287C
CA2926287C CA2926287A CA2926287A CA2926287C CA 2926287 C CA2926287 C CA 2926287C CA 2926287 A CA2926287 A CA 2926287A CA 2926287 A CA2926287 A CA 2926287A CA 2926287 C CA2926287 C CA 2926287C
Authority
CA
Canada
Prior art keywords
detector
test carrier
fault detection
demodulated
light source
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2926287A
Other languages
English (en)
French (fr)
Other versions
CA2926287A1 (en
Inventor
Gertrud Albrecht
Edgar Baumann
Markus GENTHNER-RIEGLER
Stefan Kalveram
Christian Niesporek
Kai-Oliver Schwenker
Markus Serr
Frederic Wehowski
Klaus WETTENGEL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2926287A1 publication Critical patent/CA2926287A1/en
Application granted granted Critical
Publication of CA2926287C publication Critical patent/CA2926287C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/42—Absorption spectrometry; Double beam spectrometry; Flicker spectrometry; Reflection spectrometry
    • G01J3/433—Modulation spectrometry; Derivative spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274—Calibration, base line adjustment, drift correction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers
    • G01N2201/0612—Laser diodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G01N2201/0621—Supply
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/069—Supply of sources
    • G01N2201/0696—Pulsed
    • G01N2201/0697—Pulsed lasers

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Plasma & Fusion (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2926287A 2013-11-28 2014-11-27 Method and device for determining a concentration of an analyte in a bodily fluid Active CA2926287C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13194791.3 2013-11-28
EP13194791 2013-11-28
PCT/EP2014/075780 WO2015078954A1 (en) 2013-11-28 2014-11-27 Method and device for determining a concentration of an analyte in a bodily fluid

Publications (2)

Publication Number Publication Date
CA2926287A1 CA2926287A1 (en) 2015-06-04
CA2926287C true CA2926287C (en) 2020-03-24

Family

ID=49679379

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2926287A Active CA2926287C (en) 2013-11-28 2014-11-27 Method and device for determining a concentration of an analyte in a bodily fluid

Country Status (7)

Country Link
US (1) US10274430B2 (enExample)
EP (1) EP3074758B1 (enExample)
JP (2) JP6659541B2 (enExample)
KR (1) KR102245011B1 (enExample)
CN (2) CN110261379B (enExample)
CA (1) CA2926287C (enExample)
WO (1) WO2015078954A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3591385A1 (en) 2018-07-06 2020-01-08 Roche Diabetes Care GmbH A detection method for detecting an analyte in a sample
WO2020152510A1 (en) * 2019-01-25 2020-07-30 Matai Laxman Hemoglobin analyzer
US20240094134A1 (en) * 2021-01-13 2024-03-21 Hitachi High-Tech Corporation Automatic analyzer and automatic analysis method
CN113655011B (zh) * 2021-10-20 2022-02-08 武汉新烽光电股份有限公司 一种微流控检测系统及其检测方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2934190A1 (de) * 1979-08-23 1981-03-19 Müller, Gerhard, Prof. Dr.-Ing., 7080 Aalen Verfahren und vorrichtung zur molekuelspektroskopie, insbesondere zur bestimmung von stoffwechselprodukten
JP3046610B2 (ja) * 1990-04-24 2000-05-29 松下電工株式会社 粉塵検出装置
DE4041905A1 (de) * 1990-12-27 1992-07-02 Boehringer Mannheim Gmbh Testtraeger-analysesystem
US5526120A (en) * 1994-09-08 1996-06-11 Lifescan, Inc. Test strip with an asymmetrical end insuring correct insertion for measuring
IL121279A (en) * 1996-07-16 2001-05-20 Roche Diagnostics Gmbh An analytical system with means for testing samples with too small volumes
DE19706520A1 (de) * 1997-02-19 1998-08-20 Lre Technology Partner Gmbh Meßgerät zur Bestimmung der Konzentration mindestens einer Substanz in einer Körperflüssigkeit, insbesondere Blutzuckermeßgerät
CN1131425C (zh) 1997-10-31 2003-12-17 技术化学品及产品股份有限公司 反射计
DE10061336A1 (de) * 2000-12-08 2002-06-13 Roche Diagnostics Gmbh System zur Analyse von Probeflüssigkeiten beinhaltend eine Lagekontrolleinheit
CA2366802A1 (en) * 2001-01-17 2002-07-17 Bayer Corporation Method and apparatus for using infrared readings to detect misidentification of a diagnostic test strip in a reflectance spectrometer
US20030169426A1 (en) * 2002-03-08 2003-09-11 Peterson Timothy A. Test member orientation
US20080119421A1 (en) * 2003-10-31 2008-05-22 Jack Tuszynski Process for treating a biological organism
CN100496395C (zh) * 2004-05-06 2009-06-10 日本电信电话株式会社 成分浓度测定装置和成分浓度测定装置控制方法
GB0416732D0 (en) * 2004-07-27 2004-09-01 Precisense As A method and apparatus for measuring the phase shift induced in a light signal by a sample
EP1801568A1 (de) * 2005-12-21 2007-06-27 Micronas Holding GmbH Teststreifen und Verfahren zum Messen einer Analytkonzentration in einer Probe eines biologischen Fluids
ATE491935T1 (de) * 2006-10-14 2011-01-15 Hoffmann La Roche Anordnung und verfahren zum erfassen und auswerten optischer signale
US20100187450A1 (en) * 2007-06-21 2010-07-29 Koninklijke Philips Electronics N.V. Microelectronic sensor device with light source and light detector
JP2012524277A (ja) * 2009-04-15 2012-10-11 レリア ダイアグノスティック システムズ，インク． 試験ストリップのダイナミックレンジの拡張
CN101813618A (zh) * 2010-01-07 2010-08-25 中国科学院半导体研究所 基于光声效应的多种气体同时检测装置及检测方法
EP2362207A1 (de) * 2010-01-28 2011-08-31 F. Hoffmann-La Roche AG Messsystem und Messverfahren insbesondere zur Blutzuckerbestimmung
ITMI20101730A1 (it) * 2010-09-23 2012-03-24 Fond Italiana Fegato Onlus Sistema di tipo "point of care" di misura della bilirubina totale nel plasma, in particolare di neonati
DE102011118607A1 (de) * 2011-09-14 2013-03-14 Friedrich-Schiller-Universität Jena Verfahren und Anordnung zur Streulichtmessung

Also Published As

Publication number Publication date
KR20160091897A (ko) 2016-08-03
CN110261379A (zh) 2019-09-20
EP3074758B1 (en) 2019-02-27
US20160245755A1 (en) 2016-08-25
JP2020024219A (ja) 2020-02-13
JP6659541B2 (ja) 2020-03-04
US10274430B2 (en) 2019-04-30
KR102245011B1 (ko) 2021-04-27
CA2926287A1 (en) 2015-06-04
WO2015078954A1 (en) 2015-06-04
JP2017501395A (ja) 2017-01-12
CN105992945A (zh) 2016-10-05
CN110261379B (zh) 2021-11-12
EP3074758A1 (en) 2016-10-05

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