CN110251737A - A kind of latex prophylactic being added to sodium hyaluronate - Google Patents

A kind of latex prophylactic being added to sodium hyaluronate Download PDF

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Publication number
CN110251737A
CN110251737A CN201910714980.4A CN201910714980A CN110251737A CN 110251737 A CN110251737 A CN 110251737A CN 201910714980 A CN201910714980 A CN 201910714980A CN 110251737 A CN110251737 A CN 110251737A
Authority
CN
China
Prior art keywords
layer
sodium hyaluronate
latex
added
natural rubber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910714980.4A
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Chinese (zh)
Inventor
张欢
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hunan Youfen Biotechnology Co Ltd
Original Assignee
Hunan Youfen Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hunan Youfen Biotechnology Co Ltd filed Critical Hunan Youfen Biotechnology Co Ltd
Priority to CN201910714980.4A priority Critical patent/CN110251737A/en
Publication of CN110251737A publication Critical patent/CN110251737A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/02Contraceptive devices; Pessaries; Applicators therefor for use by males
    • A61F6/04Condoms, sheaths or the like, e.g. combined with devices protecting against contagion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02Inorganic materials
    • A61L31/028Other inorganic materials not covered by A61L31/022 - A61L31/026
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04Macromolecular materials
    • A61L31/042Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials

Abstract

The invention discloses a kind of latex prophylactics for adding sodium hyaluronate, it is from the inside to the outside high flexibility caoutchouc layer and the common natural rubber of third layer including the common caoutchouc layer of first layer, the second layer, it is characterized in that, it includes flaky silicic acid magnalium powder, sodium hyaluronate, sodium lignin sulfonate and natural emulsion that the second layer, which is high flexibility caoutchouc layer,.The latex prophylactic that the present invention is added to sodium hyaluronate is effectively attached to vagina skin surface, and the function of playing lubrication skin care is used for a long time, and can improve vaginal relaxation, restores vagina tight;Lubricity is high, reduces skin injury, reduces the harmful microorganisms such as bacterium, virus to the erosion chance of human body;Nano-sheet aluminium-magnesium silicate powder is added, the flexibility of latex can be improved in the opposite sliding between nanometer layer, has better tear resistance and elasticity, draftability is good.

Description

A kind of latex prophylactic being added to sodium hyaluronate
Technical field
The invention belongs to contraceptives, and in particular to a kind of latex prophylactic for being added to sodium hyaluronate.
Background technique
Sheath is common family planning articles in people's daily life, sperm and ovum when being mainly used for separating human sexuality The combination of son, prevents from being pregnant.In the modern life, with the propagation and sprawling of the various venereal diseases such as AIDS, in sexual life, Nan Xingpei Wearing condom is a kind of most simple and effective means to venereal disease is prevented.
Sodium hyaluronate is one of molecule most hydrophilic in natural, has many benefits to human body, can improve skin-nourishing generation Thank, make skin it is tender, it is smooth, go wrinkle, increase elasticity, prevent aging, be the promotion of good Transdermal absorption again while moisturizing Agent is referred to as " natural moisturizer ".Sodium hyaluronate can be found in most cells of human body, but mainly with higher dense Degree is present in skin histology, and almost 50% sodium hyaluronate is present in skin histology in human body.Sodium hyaluronate can help skin A large amount of moisture is drawn, skin is made to keep smooth and flexible, while skin is due to keeping young containing a large amount of sodium hyaluronate Health.But with the influence of the factors such as the growth and nutrition at people's age, sunshine and environment, skin generates the ability of sodium hyaluronate It is gradually reduced, therefore the content of sodium hyaluronate can gradually decrease in skin, causes skin dehydration, wrinkles and follow the string, make one table Skin aging.Have in the prior art since the compatibility of sodium hyaluronate is good and is added frequently as lubricating additive.
Natural emulsion (raw rubber, natural rubber) is obtained from the rubber tree of cultivation, has good filming performance, wet Gel strength is high, and good mechanical properties, mechanical stability is high, and color is pure white, and foam stability is good.Natural emulsion is by processing Afterwards, there is very excellent comprehensive performance, be current most popular sheath, due to the sheath of caoutchouc latex preparation Many health problems can be caused.There is allergic reaction to human body containing substances such as rubber plant protein in natural emulsion, so seeking The substitute products of high-quality natural emulsion are looked for compel in the whole world as pressing as a fire singeing one's eyebrows, such as: alternative materials polyisoprene, poly- ammonia are updated in recent years Ester is also utilized as the substitute of natural emulsion.
By force, lubricity is good for sheath " natural sense ", effectively repairs vaginal mucosa and is damaged, improve vaginal relaxation, restores vagina Tight can promote pleasant sensation, make sexual life more harmonious, promote emotion between husband and wife;It is more reduced skin damage simultaneously Wound reduces the harmful microorganisms such as bacterium, virus to the erosion chance of human body;Effectively reduce the breakage of condom, reduce it is unexpected by Pregnant probability.
Currently, a kind of chitosan of the existing Patent No. CN201810938414.7 patent name for addition in sheath The production application process of class water-soluble lubricating liquid is disclosed dissolved with sodium hyaluronate pulvis, and agitated uniform technique makes entire moisturizing System is moist, thick and heavy, non-greasy, then lubricating fluid is equably applied on sheath glue film, or is added dropwise on sheath, makes Condom products more lubricate, and have hemostasis, anti-inflammatory, promote wound healing, skin is kept to moisten, smooth, prevent dry and send out It is dark and other effects, but dissolution of the lubricating fluid of the sheath through pulvis raw material, smear, it is easy that agglomerating, dispersion is uneven, causes Waste of raw materials increases the disadvantages of cost.
Summary of the invention
The latex prophylactic provided by the invention for being added to sodium hyaluronate, can play the function of lubrication skin care, and sodium hyaluronate is effective It is attached to vagina skin surface, long-time service can improve vaginal relaxation, restore vagina tight.
The latex prophylactic provided by the invention for being added to sodium hyaluronate includes the common natural rubber of first layer from the inside to the outside Layer, the second layer are high flexibility layer and the common caoutchouc layer of third layer;The second layer is that high flexibility layer includes flaky silicic acid magnalium Powder, sodium hyaluronate, sodium lignin sulfonate and natural emulsion.
The latex prophylactic for being added to sodium hyaluronate is prepared by following steps:
Step 1, natural rubber latex is prepared, natural emulsion, dispersing agent, thickener are mixed and stirred in parts by weight It is even to obtain the final product;
Step 2, high flexibility natural rubber latex is prepared, sodium hyaluronate and sodium lignin sulfonate are stirred in parts by weight mixed It closes, suitable water is added and carries out emulsion dispersion;200~800nm flaky silicic acid magnalium powder, stirring is added;Then it is added natural Latex stirs at a certain temperature to obtain the final product;
Step 3, natural rubber latex step 1 obtained is injected separately into first of glue groove and third road glue groove, will The high flexibility natural rubber latex that step 2 obtains is injected into second glue groove;
Step 4, the condom mould after cleaning-drying is placed on condom manufacture line, condom mould is made to immerse the One of glue groove impregnation, moving ahead reaches baking zone drying, forms first layer caoutchouc layer;
Step 5, second glue groove impregnation, dry immersion after impregnation are immersed through the condom mould after step 4 gluing And third road glue groove, dry demoulding again, forms the latex prophylactic for being added to sodium hyaluronate after glue.
Further, the flaky silicic acid magnalium powder is the 2-5wt% of high flexibility natural rubber latex.
Further, the sodium hyaluronate is the 0.1-0.2wt% of high flexibility natural rubber latex.
Further, the sodium lignin sulfonate is the 0.1-0.5wt% of high flexibility natural rubber latex.
Further, the time that the condom mould enters three glue grooves is 6-12s.
Further, temperature described in the step 2 is 60-65 DEG C, improves the compatibility and hydrophily of sodium hyaluronate.
Further, it is 24~28 degrees Celsius that optimum temperature is impregnated in the step 4, and must not impregnate less than 2 times.
The latex prophylactic provided by the invention for being added to sodium hyaluronate is effectively attached to vagina skin surface, is used for a long time To the function of lubrication skin care, vaginal relaxation can be improved, restore vagina tight;Lubricity is high, reduces skin injury, reduces thin Erosion chance of the harmful microorganisms such as bacterium, virus to human body;Middle layer is added flaky silicic acid magnalium layer and inserts material, between nanometer layer Opposite sliding the flexibility of latex can be improved, there is better tear resistance and elasticity, draftability is good.
Specific embodiment
Below with reference to specific embodiment, the present invention will be further described.
Embodiment
(1) natural rubber latex is prepared, preparation method routinely mixes natural rubber, dispersing agent simultaneously in parts by weight It stirs evenly to get corresponding natural rubber latex, the day that weight ratio is divided into 800 parts is added specially in clean mixing tank 4 parts of right latex, 2 parts of neopelex (dispersing agent) and Sodium Polyacrylate (thickener) add vulcanizing agent, promote Agent, anti-aging agent, wherein 8 parts of sulphur (vulcanizing agent), 6 parts of dibenzyl dithio amino gallic acid zinc (promotor), 2,6- di-t-butyl- 7 parts of 4- methylphenol (anti-aging agent) is 50 DEG C of ultrasonic agitation processing in temperature, and the time is 50 minutes;
(2) high flexibility natural rubber latex is prepared, sodium hyaluronate is stirred in parts by weight with sodium lignin sulfonate, is added Enter suitable water and carries out emulsion dispersion;16 parts of 200~800nm flaky silicic acid magnalium powder, stirring is added;Then genuine milk is added 750 parts of glue, 1.5 parts of sodium hyaluronates, 3 parts of sodium lignin sulfonates are weighed, suitable water is added and carries out emulsion dispersion at 60-65 DEG C, Time is 30 minutes;
(3) natural rubber latex for obtaining step 1 is injected separately into first of glue groove and third road glue groove, by step The 2 high flexibility natural rubber latexes obtained are injected into second glue groove;
(4) condom mould after cleaning-drying is placed on condom manufacture line, condom mould is made to immerse first Road glue groove impregnation, moving ahead reaches baking zone drying, forms first layer caoutchouc layer, dipping optimum temperature is 25 DEG C, and impregnates 2 It is secondary;
(5) second glue groove impregnation is immersed through the condom mould after step 4 gluing, it is dry after impregnation to immerse and the Three glue grooves, dipping optimum temperature is 25 DEG C, and is impregnated 2 times, and dry demoulding again, then passes through crimping, chlorination, bubble after dipping It washes, rinse, parking processing, forming the latex prophylactic for being added to sodium hyaluronate.
The present embodiment finished product and commercially available ordinary condom stretch and the comparative test of bursting property, testing standard are adopted It is carried out with GB 7544.1-1999 rubber condoms.
From following table it can be seen that latex prophylactic of the invention has better tear resistance and elasticity, draftability is good.
The present embodiment finished product and commercially available ordinary condom are lubricated to the comparative test of performance, testing standard uses GB 10006-88 plastic film and the measurement of thin slice measuring friction coefficient method.
From following table it can be seen that latex prophylactic of the invention has better greasy property.
Performance indicator Embodiment Comparative example
Confficient of static friction 0.025 1.323
Dynamic friction coefficient 0.019 1.297

Claims (8)

1. a kind of latex prophylactic for adding sodium hyaluronate is from the inside to the outside height including the common caoutchouc layer of first layer, the second layer Flexible caoutchouc layer and the common natural rubber of third layer, which is characterized in that the second layer is that high flexibility caoutchouc layer includes Flaky silicic acid magnalium powder, sodium hyaluronate, sodium lignin sulfonate and natural emulsion.
2. the latex prophylactic of addition sodium hyaluronate according to claim 1, which is characterized in that use following step system It is standby, step 1, natural rubber latex is prepared, natural emulsion, dispersing agent, thickener are mixed and stirred for uniformly in parts by weight, then Vulcanizing agent, promotor, anti-aging agent emulsion dispersion is added to obtain the final product;
Step 2, high flexibility natural rubber latex is prepared, sodium hyaluronate is stirred in parts by weight with sodium lignin sulfonate, is added Enter suitable water and carries out emulsion dispersion;200~800nm flaky silicic acid magnalium powder, stirring is added;Then natural emulsion is added, It stirs at a certain temperature to obtain the final product;
Step 3, natural rubber latex step 1 obtained is injected separately into first of glue groove and third road glue groove, by step 2 The high flexibility natural rubber latex of acquisition is injected into second glue groove;
Step 4, the condom mould after cleaning-drying is placed on condom manufacture line, immerses condom mould first Glue groove impregnation, moving ahead reaches baking zone drying, forms first layer caoutchouc layer;
Step 5, second glue groove impregnation is immersed through the condom mould after step 4 gluing, it is dry after impregnation to immerse and the Three glue grooves, dry demoulding again after impregnation, then routinely crimping, chlorination, foam washing, rinsing, drying process formation are added to glass The latex prophylactic of uric acid.
3. the latex prophylactic of addition sodium hyaluronate according to claim 2, which is characterized in that the flaky silicic acid magnesium aluminium powder Body is the 2-5wt% of high flexibility natural rubber latex.
4. the latex prophylactic of addition sodium hyaluronate according to claim 2, which is characterized in that the sodium hyaluronate is high flexibility The 0.1-0.2wt% of natural rubber latex.
5. the latex prophylactic of addition sodium hyaluronate according to claim 2, which is characterized in that the sodium lignin sulfonate is The 0.1-0.5wt% of high flexibility natural rubber latex.
6. the latex prophylactic of addition sodium hyaluronate according to claim 5, which is characterized in that the condom mould enters The time of three glue grooves is 6-12s.
7. the latex prophylactic of addition sodium hyaluronate according to claim 6, which is characterized in that temperature described in step 2 is 60- 65℃。
8. the latex prophylactic of addition sodium hyaluronate according to claim 7, which is characterized in that in the step 4 or step 5 Impregnating optimum temperature is 24~28 degrees Celsius, and must not impregnate less than 2 times.
CN201910714980.4A 2019-08-06 2019-08-06 A kind of latex prophylactic being added to sodium hyaluronate Pending CN110251737A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910714980.4A CN110251737A (en) 2019-08-06 2019-08-06 A kind of latex prophylactic being added to sodium hyaluronate

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Application Number Priority Date Filing Date Title
CN201910714980.4A CN110251737A (en) 2019-08-06 2019-08-06 A kind of latex prophylactic being added to sodium hyaluronate

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CN110251737A true CN110251737A (en) 2019-09-20

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111820511A (en) * 2020-08-20 2020-10-27 安丹达工业技术(上海)有限公司 Rubber gloves with cool feeling and preparation method thereof

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US20020131988A1 (en) * 1999-12-16 2002-09-19 Foster Todd P. Pharmaceutical implant containing immediate-release and sustained-release components and method of administration
US20030134803A1 (en) * 2002-01-15 2003-07-17 The Regents Of The University Of California Use of sulfonated compounds as a barrier contraceptive
EP2108446A1 (en) * 2008-04-08 2009-10-14 Süd-Chemie Ag Solid odour adsorbent based on zinc ricinoleates and related compounds
CN109153823A (en) * 2016-09-01 2019-01-04 株式会社Lg化学 Latex composition and moulded products prepared therefrom for dip forming
CN109602959A (en) * 2018-11-20 2019-04-12 广州双乳胶制品有限公司 A kind of colorful sheath and preparation method thereof
CN109674570A (en) * 2019-01-28 2019-04-26 桂林恒保健康防护有限公司 A kind of quick-fried pearl condom and preparation method thereof of bilayer laser boring
CN109880190A (en) * 2019-02-15 2019-06-14 北京胤牌科技有限公司 A kind of production method of special-shaped condom
CN109928062A (en) * 2019-01-07 2019-06-25 广州万方健医药有限公司 A kind of sheath system and its packaging method

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US20020131988A1 (en) * 1999-12-16 2002-09-19 Foster Todd P. Pharmaceutical implant containing immediate-release and sustained-release components and method of administration
US20030134803A1 (en) * 2002-01-15 2003-07-17 The Regents Of The University Of California Use of sulfonated compounds as a barrier contraceptive
EP2108446A1 (en) * 2008-04-08 2009-10-14 Süd-Chemie Ag Solid odour adsorbent based on zinc ricinoleates and related compounds
CN109153823A (en) * 2016-09-01 2019-01-04 株式会社Lg化学 Latex composition and moulded products prepared therefrom for dip forming
CN109602959A (en) * 2018-11-20 2019-04-12 广州双乳胶制品有限公司 A kind of colorful sheath and preparation method thereof
CN109928062A (en) * 2019-01-07 2019-06-25 广州万方健医药有限公司 A kind of sheath system and its packaging method
CN109674570A (en) * 2019-01-28 2019-04-26 桂林恒保健康防护有限公司 A kind of quick-fried pearl condom and preparation method thereof of bilayer laser boring
CN109880190A (en) * 2019-02-15 2019-06-14 北京胤牌科技有限公司 A kind of production method of special-shaped condom

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111820511A (en) * 2020-08-20 2020-10-27 安丹达工业技术(上海)有限公司 Rubber gloves with cool feeling and preparation method thereof

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Application publication date: 20190920