CN110251583A - A kind of preparation method of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice - Google Patents
A kind of preparation method of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice Download PDFInfo
- Publication number
- CN110251583A CN110251583A CN201910670357.3A CN201910670357A CN110251583A CN 110251583 A CN110251583 A CN 110251583A CN 201910670357 A CN201910670357 A CN 201910670357A CN 110251583 A CN110251583 A CN 110251583A
- Authority
- CN
- China
- Prior art keywords
- vinegar
- schisandra chinensis
- preparation
- demulcen
- steams
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to a kind of preparation methods of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice, and described method includes following steps: net system: selecting schisandra chinensis medicinal material, remove impurity；Vinegar steams: the Schisandra chinensis after net system being mixed with vinegar, being placed in steamer for placement steams, and collects decoction；Demulcen: being placed in vinegar for Schisandra chinensis of the vinegar after steamed and steam in the decoction of collection step, infiltration；It is dry: the Schisandra chinensis after demulcen being placed in baking oven and is dried；Packaging: the Schisandra chinensis after drying is vacuum-packed.The decoction that the present invention steams during steaming is used for demulcen, its effective component into playing a role in steamed FRUCTUS SCHISANDRAE with vinegar, is not wasted raw material as often as possible.This process carries out demulcen without using other juice, eliminates the preparation for other juice.
Description
Technical field
The present invention relates to Technology of Processing Chinese Herbal Medicines fields, are steamed more particularly, to one kind by mature vinegar and prepare steamed FRUCTUS SCHISANDRAE with vinegar drink
The method of piece.
Background technique
The function of steamed FRUCTUS SCHISANDRAE with vinegar with cure mainly are as follows: astringency inducing, supplementing qi and promoting the production of body fluid, tonifying kidney and calming nerves.For long-last cough and virtual asthma, nocturnal emission is sliding
Essence, enuresis frequent micturition, endless diarrhea, spontaneous sweating, injury thirst, Heat Diabetes, palpitation and insomnia.The conventional method big gun of steamed FRUCTUS SCHISANDRAE with vinegar
Method processed is recorded in " Chinese Pharmacopoeia " 2015 version one, for " Schisandra chinensis is taken, according to the method for steaming, is steamed to surface atropurpureus or dark brown,
Take out it is dry to get." conventionally produced low efficiency, yield is low, and energy consumption is high, is not suitable for large-scale industrial production.
Summary of the invention
In view of the deficiencies of the prior art, the invention discloses a kind of preparation methods of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice.
The technical solution adopted in the present invention is as follows:
A kind of preparation method of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice, the method includes vinegar to steam step and demulcen step；It is steamed in the vinegar
In step, Schisandra chinensis is mixed with vinegar, being placed in steamer for placement steams, and collects the decoction after steamed in steamer；?
In the demulcen step, Schisandra chinensis of the vinegar after steamed is placed in step vinegar and is steamed in decoction collected by step, infiltration.
Its further technical solution is, further includes net system step before the vinegar steams step；The net system step is
Schisandra chinensis medicinal material is selected, impurity is removed.
Its further technical solution are as follows: it is tilting-type digester that the vinegar, which steams the steamer in step,.
Its further technical solution are as follows: the vinegar steams the standing time in step for 2~4h.
Its further technical solution are as follows: it is 4~8h that the vinegar, which steams the steaming time in step,.
Its further technical solution are as follows: the infiltrating time in the demulcen step is 4~8h.
Its further technical solution are as follows: after the demulcen step further include drying steps, the drying steps are
Schisandra chinensis after demulcen is placed in baking oven and is dried.
Its further technical solution are as follows: the drying temperature in the drying steps is 60~80 DEG C.
Its further technical solution are as follows: Schisandra chinensis being placed in baking oven in the drying steps is dried to Schisandra chinensis
Water content < 14%.
Beneficial effects of the present invention are as follows:.
The decoction that the present invention steams during steaming is used for demulcen, its effective component is enabled as often as possible to enter vinegar
It plays a role, does not waste raw material in Schisandra chinensis.This process carries out demulcen without using other juice, eliminates for other juice
Preparation.
The extract content > 28% for the steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice that the present invention is prepared, schizandrin (C24H32O7) content
> 0.40%, quality is high, meets steamed FRUCTUS SCHISANDRAE with vinegar prepared slice quality standard, and preparation method is simple, saves time and the energy, is suitable for
Industrialized production.
Specific embodiment
The preparation method of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice disclosed in this invention specifically includes the following steps:
(1) net system: selecting good schisandra chinensis medicinal material, removes impurity；
(2) vinegar steams: the Schisandra chinensis after net system being mixed with vinegar, being placed in steamer for placement is steamed by steam
System, and collect decoction；Wherein, the preferred mature vinegar of vinegar.
(3) demulcen: Schisandra chinensis of the vinegar after steamed being placed in the decoction of step (2) collection, infiltration；
(4) dry: the Schisandra chinensis after demulcen being placed in baking oven and is dried；
(5) it packs: the Schisandra chinensis after drying is vacuum-packed, be placed at aeration-drying and store, steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice is made.
Preferably, steamer is tilting-type digester in step (2).
Preferably, the standing time in step (2) is 2~4h.
Preferably, the steaming time in step (2) is 4~8h.
Preferably, the infiltrating time in step (3) is 4~8h.
Preferably, the drying temperature in step (4) is 60~80 DEG C.
Preferably, Schisandra chinensis is placed in baking oven to the water content < 14% for being dried to Schisandra chinensis in step (4).
Below with reference to multiple embodiments, illustrate a specific embodiment of the invention.
Embodiment 1.
Embodiment 1 includes the following steps:
(1) net system: selecting high-quality schisandra chinensis medicinal material, removes impurity；
(2) vinegar steam: the Schisandra chinensis after net system is mixed with mature vinegar, placement 4h, be placed in tilting-type digester, pass through
Steam steams 4h, and collects decoction；
(3) demulcen: vinegar is steamed into Schisandra chinensis obtained and is placed in the decoction of step (2) collection, 8h is infiltrated；
(4) dry: will to be placed in baking oven by the Schisandra chinensis of step (3) processing, drying temperature is 60 DEG C, is dried to Schisandra chinensis
Water content is 12%；
(5) it packs: the Schisandra chinensis after drying is vacuum-packed, be placed at aeration-drying and store, the steamed FRUCTUS SCHISANDRAE with vinegar is made
Medicine materical crude slice.
Embodiment 2.
Embodiment 2 includes the following steps:
(1) net system: selecting high-quality schisandra chinensis medicinal material, removes impurity；
(2) vinegar steam: the Schisandra chinensis after net system is mixed with mature vinegar, placement 2h, be placed in steamer, carried out by steam
8h is steamed, and collects decoction；
(3) demulcen: vinegar is steamed into Schisandra chinensis obtained and is placed in the decoction of step (2) collection, 4h is infiltrated；
(4) dry: will to be placed in baking oven by the Schisandra chinensis of step (3) processing, drying temperature is 70 DEG C, is dried to water content
It is 13%；
(5) it packs: the Schisandra chinensis after drying is vacuum-packed, be placed at aeration-drying and store, the steamed FRUCTUS SCHISANDRAE with vinegar is made
Medicine materical crude slice.
Embodiment 3.
Embodiment 3 includes the following steps:
(1) net system: selecting high-quality schisandra chinensis medicinal material, removes impurity；
(2) vinegar steam: the Schisandra chinensis after net system is mixed with mature vinegar, placement 3h, be placed in steamer, carried out by steam
6h is steamed, and collects decoction；
(3) demulcen: vinegar is steamed into Schisandra chinensis obtained and is placed in the decoction of step (2) collection, 6h is infiltrated；
(4) dry: will to be placed in baking oven by the Schisandra chinensis of step (3) processing, drying temperature is 80 DEG C, is dried to water content
It is 11%；
(5) it packs: the Schisandra chinensis after drying is vacuum-packed, be placed at aeration-drying and store, the steamed FRUCTUS SCHISANDRAE with vinegar is made
Medicine materical crude slice.
Comparative example 1.
Difference from Example 1 is only that step (2) is passed through steam and carries out steaming 3h, Schisandra chinensis surface after steaming
Kermesinus.Remaining step is same as Example 1.
Comparative example 2.
Difference from Example 1 is only that step (2) is passed through steam and carries out steaming 9h, Schisandra chinensis surface after steaming
Black.Remaining step is same as Example 1.
Comparative example 3.
Difference from Example 1 is only that it is 14% that step (4) is dried to water content at 85 DEG C, remaining step and reality
It is identical to apply example 1.
Comparative example 4.
Difference from Example 1 is only that, step (4) is dried to water content 13% at 85 DEG C, remaining step and reality
It is identical to apply example 1.
This product powder lg that Example 1~3 and comparative example 1~4 are prepared respectively, adds chloroform 20ml, adds
Heat reflux 30 minutes, filtration, filtrate is evaporated, and residue adds chloroform 1ml to make to dissolve, as test solution.Separately take Schisandra chinensis
Control medicinal material 1g, is made in the same way of control medicinal material solution.Schizandrin A reference substance is taken again, adds chloroform that every 1ml is made containing 1mg
Solution, as reference substance solution.It is tested according to thin-layered chromatography (general rule 0502), draws above-mentioned each 2 μ l of three kinds of solution, respectively point
In on same silica GF254 lamellae, it is with petroleum ether (30~60 DEG C)-Ethyl formate-formic acid (15:5:1) upper solution
Solvent is unfolded, and takes out, dries, set and inspect under ultraviolet lamp (254nm).In sample chromatogram, with reference medicine chromatography and
On the corresponding position of reference substance chromatography, the spot of same color is shown.The content value of each ingredient of measurement is as shown in table 1.
Table 1
The extract content for the steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice that method of the invention is prepared it can be seen from the data of table 1 can
Up to 30.1-33.2%, schizandrin (C24H32O7) content is 0.51-0.67%, quality is high, meets steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice matter
Amount standard.
The Applicant declares that the present invention is explained by the above embodiments method detailed of the invention, but the present invention not office
Be limited to above-mentioned method detailed, that is, do not mean that the invention must rely on the above detailed methods to implement.Technical field
Technical staff it will be clearly understood that any improvement in the present invention, equivalence replacement and auxiliary element to each raw material of product of the present invention
Addition, selection of concrete mode etc., all of which fall within the scope of protection and disclosure of the present invention.
Claims (9)
1. a kind of preparation method of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice, which is characterized in that the method includes vinegar to steam step and demulcen step；?
The vinegar steams in step, and Schisandra chinensis is mixed with vinegar, and being placed in steamer for placement steams, and collection steam after in steamer
Decoction；In the demulcen step, Schisandra chinensis of the vinegar after steamed is placed in step vinegar and is steamed in decoction collected by step, infiltration.
2. preparation method according to claim 1, which is characterized in that further include net system step before the vinegar steams step
Suddenly；The net system step is to select schisandra chinensis medicinal material, removes impurity.
3. preparation method according to claim 1, it is characterised in that: it is tilting-type boiling that the vinegar, which steams the steamer in step,
Pot.
4. preparation method according to claim 1, it is characterised in that: the vinegar steams the standing time in step for 2~4h.
5. preparation method according to claim 1, it is characterised in that: it is 4~8h that the vinegar, which steams the steaming time in step,.
6. preparation method according to claim 1, it is characterised in that: the infiltrating time in the demulcen step is 4~8h.
7. preparation method according to claim 1, which is characterized in that after the demulcen step further include dry step
Suddenly, the drying steps are that the Schisandra chinensis after demulcen is placed in baking oven to dry.
8. preparation method according to claim 7, it is characterised in that: the drying temperature in the drying steps is 60~80
℃。
9. preparation method according to claim 1, it is characterised in that: Schisandra chinensis is placed in baking in the drying steps
The water content < 14% of Schisandra chinensis is dried in case.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910670357.3A CN110251583A (en) | 2019-07-23 | 2019-07-23 | A kind of preparation method of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910670357.3A CN110251583A (en) | 2019-07-23 | 2019-07-23 | A kind of preparation method of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110251583A true CN110251583A (en) | 2019-09-20 |
Family
ID=67927976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910670357.3A Pending CN110251583A (en) | 2019-07-23 | 2019-07-23 | A kind of preparation method of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110251583A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114767761A (en) * | 2022-06-01 | 2022-07-22 | 安国市同義中药饮片有限公司 | Preparation method of vinegar schisandra chinensis |
-
2019
- 2019-07-23 CN CN201910670357.3A patent/CN110251583A/en active Pending
Non-Patent Citations (4)
| Title |
|---|
| FANGZHOU YIN等: "Study of organic acids in Schisandrae Chinensis Fructus after vinegar processing", 《JOURNAL OF SEPARATION SCIENCE》 * |
| 何晓晖等: "《旴江医学研究》", 31 March 2018, 中国中医药出版社 * |
| 叶定江等: "《中药炮制学辞典》", 30 June 2005, 上海科学技术出版社 * |
| 王馨雅等: "五味子不同炮制品对大鼠肾阳虚的改善作用研究", 《现代药物与临床》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114767761A (en) * | 2022-06-01 | 2022-07-22 | 安国市同義中药饮片有限公司 | Preparation method of vinegar schisandra chinensis |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108042709A (en) | A kind of steamed sealwort concocting method | |
| CN101948376B (en) | Rapid extraction and separation method of paeonolum | |
| CN102302553B (en) | Extraction method of key components of Chinese magnoliavine fruit medicament | |
| CN105199853A (en) | Extraction method of raw ginger essential oil | |
| CN104611137A (en) | Extraction method of chrysanthemum morifolium volatile oil | |
| CN107245251A (en) | A kind of preparation method and application of blueberry leaf and its extract | |
| CN107982422A (en) | A kind of preparation method of stir-baked RHIZOMA POLYGONATI with yellow rice wine medicine materical crude slice | |
| CN110251583A (en) | A kind of preparation method of steamed FRUCTUS SCHISANDRAE with vinegar medicine materical crude slice | |
| CN108295114A (en) | The method for extraction and purification of phenolic acid class and flavones ingredient in Salvia miltiorrhiza stem | |
| CN107998187A (en) | A kind of concocting method of prepared fleece flower root | |
| CN102653701A (en) | Method for extracting suaeda salsa seed oil | |
| CN112022960A (en) | Preparation method of polygonatum sibiricum traditional Chinese medicine decoction pieces | |
| CN101966212A (en) | Preparation method and use of Syringa pubescens bark extract | |
| CN109010405B (en) | Processing method of fresh cut white atractylodes rhizome in producing area | |
| US20100303974A1 (en) | Method of preparing an extract from multiple botanic herbs by an ultrasonic way under a low temperature | |
| CN109423358A (en) | A kind of extracting method of Chinese small iris volatile oil | |
| CN113332341A (en) | Processing method of white paeony root and white paeony root processed product | |
| CN110684634B (en) | Method for processing distilled health wine by using dregs of medicinal decoction of leaching health wine | |
| CN102727540A (en) | Method for preparing red bayberry leaf extract | |
| CN1094915A (en) | With the Semen Crataegi is the processing method of feedstock production beverage, oil plant and gac | |
| CN101926933A (en) | Chinese medicinal composition for treating gastritis, gastric ulcer and duodenal ulcer and identification method thereof | |
| CN110746436A (en) | Method for extracting coumarin compounds in radix angelicae and radix angelicae extract | |
| CN103169912A (en) | Improvement for preparation method of Chinese material medical preparation for treating primary hepatic carcinoma | |
| CN110251562A (en) | A kind of preparation method of wine fruit of glossy privet medicine materical crude slice | |
| CN102507837A (en) | Detection method of lipid-lowering and blood-circulation-promoting capsule |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190920 |
|
| RJ01 | Rejection of invention patent application after publication |