CN110236967A - 一种祛痘凝胶 - Google Patents

一种祛痘凝胶 Download PDF

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CN110236967A
CN110236967A CN201910546502.7A CN201910546502A CN110236967A CN 110236967 A CN110236967 A CN 110236967A CN 201910546502 A CN201910546502 A CN 201910546502A CN 110236967 A CN110236967 A CN 110236967A
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黄彩仪
王丽辉
林锦雄
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Guangzhou I & B Biological Technology Co Ltd
Guangzhou Aibei Biological Technology Co Ltd
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Abstract

本发明公开了一种祛痘凝胶，包含以下重量百分含量的组分：金缕梅提取物1～6％、小球藻提取物0.008～0.15％、肉豆蔻酰六肽‑5 1～5％、硅烷二醇水杨酸酯0.5～5％和蜂王浆控油因子0.5～6％；所述蜂王浆控油因子包含重量百分含量为0.8～1.5％的蜂王浆。本发明所述祛痘凝胶采用金缕梅提取物、小球藻提取物、肉豆蔻酰六肽‑5、硅烷二醇水杨酸酯和蜂王浆控油因子进行复配，能预防和去除青春痘、暗疮，并且能修复痘肌，控油祛痘的效果显著。

Description

一种祛痘凝胶
技术领域
本发明属于化妆品技术领域，具体涉及一种祛痘凝胶。
背景技术
青春痘(又叫痤疮)的发生主要与皮脂分泌过多、毛囊皮脂腺导管堵塞、细菌感染和炎症反应等因素密切相关，进入青春期后人体内雄激素特别是睾酮的水平迅速升高，促进皮脂腺发育并产生大量皮脂，同时毛囊皮脂腺导管的角化异常造成导管堵塞，皮脂排出障碍，形成角质栓即微粉刺，毛囊中多种微生物尤其是痤疮丙酸杆菌大量繁殖，痤疮丙酸杆菌产生的脂酶分解皮脂生成游离脂肪酸，同时趋化炎症细胞和介质，最终诱导并加重炎症反应。青春痘严重影响人的容貌和自信，对人们的工作、生活产生消极影响。因此，为了解决青春痘现象，多种祛痘产品被研发出来，其中一种就包括了祛痘凝胶，然而市面上的一些祛痘凝胶不仅祛痘效果慢，甚至于有些产品还能使得痘痘加重，或者有些祛痘产品虽然在使用的过程中能够祛除痘痘，但是停止使用后皮肤表面可能会再一次出现痘痘的症状。但本产品的祛痘效果不仅好，停止使用后原生长的痘痘处还能不易再生成痘痘。
发明内容
本发明的目的在于克服现有技术存在的不足之处而提供一种祛痘凝胶。
为实现上述目的，本发明采取的技术方案为：一种祛痘凝胶，包含以下重量百分含量的组分：金缕梅提取物1～6％、小球藻提取物0.8～3％、肉豆蔻酰六肽-5 1～5％、硅烷二醇水杨酸酯0.5～5％和蜂王浆控油因子0.5～6％所述蜂王浆控油因子包含重量百分含量为0.8～1.5％的蜂王浆。
痤疮丙酸杆菌为痤疮的最主要病因之一，金黄色葡萄球菌亦可在痤疮发病中起作用。本发明所述祛痘凝胶中添加了抗菌肽—肉豆蔻酰六肽-5，能有效抑制痤疮丙酸杆菌和金黄色葡萄球菌的增殖，还能缓解皮脂腺细胞的过度角化，可有效预防和祛除不同类型的青春痘、暗疮，使肌肤恢复平滑细腻。
小球藻提取物中含有小球藻生长因子(C.G.F)，这种由小分子糖和蛋白肽组成的独特的活性物质能够深层净化肌肤PM2.5，修复细胞及DNA损伤，对抗紫外线损伤。本发明所述小球藻提取物为上海伽誉生物科技有限公司公司生产的型号为2代小球藻深层净化因子。
本发明所述蜂王浆控油因子为Provital Group公司生产的商品名为AC RoyalJelly Extract蜂王浆控油因子，其中含有丁二醇、10-羟基癸酸、癸二酸、1,10-癸二醇和蜂王浆，能有效减少活性皮脂腺体的数量，降低活性皮脂腺体的皮脂分泌量，强效抑制痤疮丙酸杆菌。
硅烷二醇水杨酸酯的作用是能够参与角质细胞和成纤维细胞的交流，帮助皮肤提高自然抵抗力，从而达到安肤和抗炎的作用，具有很好的消炎和抗自由基能力。
本发明将金缕梅提取物、小球藻提取物、肉豆蔻酰六肽-5、硅烷二醇水杨酸酯和蜂王浆控油因子进行复配，能预防和去除青春痘、暗疮，并且能修复痘肌，控油祛痘的效果显著。
优选地，所述祛痘凝胶包含以下重量百分含量的组分：金缕梅提取物2～4％、小球藻提取物0.8～1.5％、肉豆蔻酰六肽-5 2～4％、硅烷二醇水杨酸酯1～3％和蜂王浆控油因子1～3％。各成分采用上述配比复配时，祛痘效果和肌肤恢复效果更佳。
优选地，所述祛痘凝胶包含以下重量百分含量的组分：金缕梅提取物3％、小球藻提取物1％、肉豆蔻酰六肽-5 3％、硅烷二醇水杨酸酯2％和蜂王浆控油因子2％。各成分采用上述配比复配时，祛痘效果和肌肤恢复效果最佳，且能控制成本。
优选地，所述祛痘凝胶还包含尿囊素、保湿剂、螯合剂、增稠剂和防腐剂。
优选地，所述尿囊素在所述祛痘凝胶中的重量百分含量为0.1～0.2％。
优选地，所述保湿剂包含1.3-丁二醇和透明质酸钠；所述1.3-丁二醇在所述祛痘凝胶中的重量百分含量为1～6％；所述透明质酸钠在所述祛痘凝胶中的重量百分含量为0.01～0.1％。
优选地，所述螯合剂包含EDTA-2Na；所述增稠剂包含丙烯酸羟乙酯、丙烯酰二甲基牛磺酸钠共聚物的混合物、阿拉伯胶树胶和黄原胶的混合物；在所述祛痘凝胶中，所述EDTA-2Na的重量百分含量为0.02～0.1％；所述丙烯酸羟乙酯、丙烯酰二甲基牛磺酸钠共聚物的混合物的重量百分含量为0.8～1.8％；所述阿拉伯胶树胶和黄原胶的混合物的重量百分含量为0.1～0.5％；所述羟苯甲酯的重量百分含量为0.08～0.2％；所述苯氧乙醇、羟苯乙酯、羟苯甲酯和乙基己基甘油的混合物的重量百分含量为0.2～0.5％。
丙烯酸羟乙酯(和)丙烯酰二甲基牛磺酸钠共聚物可以采用广州百好博有限公司型号为EMT-10的产品；阿拉伯胶树胶和黄原胶的混合物可以为广州百好博有限公司型号为AX的产品，所述防腐剂可以选择常规的防腐剂，优选使用广州亨安精细化工有限公司的MP和德国舒美euxyl K350，euxyl K350为苯氧乙醇、羟苯甲酯、羟苯乙酯和乙基己基甘油的混合物。采用上述成分和配比的增稠剂、螯合剂和防腐剂能保证祛痘凝胶在长时间内性状均一稳定，粘度适中，能长时间存放。
优选地，所述祛痘凝胶由以下重量百分含量的组分：金缕梅提取物2～4％、小球藻提取物0.8～1.5％、肉豆蔻酰六肽-5 2～4％、硅烷二醇水杨酸酯1～3％、蜂王浆控油因子1～3％、尿囊素0.1～0.2％、1.3-丁二醇2～4％、透明质酸钠0.01～0.1％、EDTA-2Na 0.02～0.1％、丙烯酸羟乙酯和丙烯酰二甲基牛磺酸钠共聚物的混合物0.8～1.8％、阿拉伯胶树胶和黄原胶的混合物0.1～0.5％、羟苯甲酯0.08～0.2％、苯氧乙醇、羟苯乙酯、羟苯甲酯和乙基己基甘油的混合物0.2～0.5％、薰衣草精油0.01～0.05％和余量的水。采用上述配方的祛痘凝胶的祛痘效果和皮肤的修复效果较好。
优选地，所述祛痘凝胶由以下重量百分含量的组分：金缕梅提取物3％、小球藻提取物1％、肉豆蔻酰六肽-5 3％、硅烷二醇水杨酸酯2％、蜂王浆控油因子2％、尿囊素0.15％、1.3-丁二醇3％、透明质酸钠0.05％、EDTA-2Na 0.05％、丙烯酸羟乙酯和丙烯酰二甲基牛磺酸钠共聚物的混合物1.5％、阿拉伯胶树胶和黄原胶的混合物0.3％、羟苯甲酯0.1％、苯氧乙醇、羟苯乙酯、羟苯甲酯和乙基己基甘油的混合物0.35％、薰衣草精油0.02％和余量的水。尤其是在上述配比下，用户使用反馈最佳，预防痤疮和修复痘痕效果均显著，且凝胶的性状均一，粘度适中，长期保存不变质。
除上述组分有明确的要求外，在无损本发明的效果的范围内，本领域技术人员可以根据添加或使用其他辅料成分，如香精、色素等。
本发明的有益效果在于：本发明提供了一种祛痘凝胶，本发明所述祛痘凝胶采用金缕梅提取物、小球藻提取物、肉豆蔻酰六肽-5、硅烷二醇水杨酸酯和蜂王浆控油因子进行复配，能预防和去除青春痘、暗疮，并且能修复痘肌，控油祛痘的效果显著。
具体实施方式
实施例和对比例中的羟苯甲酯为购自广州亨安精细化工有限公司；EDTA-2Na为购自广州百好博有限公司；尿囊素为购自广州汇朗生物科技有限公司；丙烯酸羟乙酯(和)丙烯酰二甲基牛磺酸钠共聚物购自广州百好博有限公司；1.3-丁二醇为购自广州恒滔贸易有限公司；透明质酸钠为购自华熙生物科技有限公司；阿拉伯胶树胶和黄原胶的混合物为购自广州百好博有限公司；金缕梅提取物为购自广州百好博有限公司；小球藻提取物为购自上海伽誉生物科技有限公司，其中有效成分小球藻提取物的含量为1～5％；肉豆蔻酰六肽-5为购自维琪生物科技有限公司；蜂王浆控油因子为购自Provital Group公司生产的商品名为AC Royal Jelly Extract蜂王浆控油因子，蜂王浆控油因子中包含重量百分含量为约10％的蜂王浆；德国舒美euxyl K350为苯氧乙醇、羟苯甲酯、羟苯乙酯和乙基己基甘油的混合物。
为更好的说明本发明的目的、技术方案和优点，下面将结合具体实施例对本发明作进一步说明。
实施例1～5和对比例1～5
实施例1～5和对比例1～5所述祛痘凝胶的配方见表1，实施例1～5和对比例1～5所述祛痘凝胶的制备方法为：将A相混合搅拌加热到80℃-85℃，搅拌均匀并降温，待温度降到45℃-50℃时，把B相中的原料加入，再次搅拌均匀即得所述祛痘凝胶。
表1实施例1～5和对比例1～5所述祛痘凝胶的配方
实施例6
测试实施例1～5和对比例1～5以及市售祛痘产品所述祛痘凝胶的效果，测试方法为：选取110名年龄18-40岁脸部长痘痘的志愿者，脸部肌肤状态表现为油腻瘙痒、痘痘，平均分为11组，每组男女各半，同时以现有技术中的常规祛痘产品作为对照组。每组受试者每天早晚都取适量的实施例1～5、对比例1～5和对照组涂于脸上的痘痘，统计每组志愿者痘痘愈合的天数，并取平均值；统计每组志愿者脸部油腻瘙痒状态是否有所改善；痘痘愈合后不再使用，然后两周内观察痘痘原生长出是否还会再次生长。测试结果见表2。
表2实施例1～5和对比例1～5以及市售祛痘产品所述祛痘凝胶的测试结果
由表2的数据可以得出，实施例1～5所述祛痘凝胶的控油祛痘效果更好一点，特别是实施例1的控油祛痘效果最好，对比例1～5所述祛痘凝胶缺少金缕梅提取物、小球藻提取物、肉豆蔻酰六肽-5、蜂王浆控油因子和硅烷二醇水杨酸酯中的一种，其控油祛痘效果均不如实施例1，说明各成分在有效范围内复配能达到较好的控油祛痘效果，而实施例1～5所述祛痘凝胶的祛痘效果均优于市售常规的祛痘产品。
最后所应当说明的是，以上实施例仅用以说明本发明的技术方案而非对本发明保护范围的限制，尽管参照较佳实施例对本发明作了详细说明，本领域的普通技术人员应当理解，可以对本发明的技术方案进行修改或者等同替换，而不脱离本发明技术方案的实质和范围。

Claims (9)

1.一种祛痘凝胶，其特征在于，包含以下重量百分含量的组分：金缕梅提取物1～6％、小球藻提取物0.008～0.15％、肉豆蔻酰六肽-5 1～5％、硅烷二醇水杨酸酯0.5～5％和蜂王浆控油因子0.5～6％；所述蜂王浆控油因子包含重量百分含量为0.8～1.5％的蜂王浆。
2.如权利要求1所述祛痘凝胶，其特征在于，所述祛痘凝胶包含以下重量百分含量的组分：金缕梅提取物2～4％、小球藻提取物0.01～0.05％、肉豆蔻酰六肽-5 2～4％、硅烷二醇水杨酸酯1～3％和蜂王浆控油因子1～3％。
3.如权利要求1所述祛痘凝胶，其特征在于，所述祛痘凝胶包含以下重量百分含量的组分：金缕梅提取物3％、小球藻提取物0.03％、肉豆蔻酰六肽-5 3％、硅烷二醇水杨酸酯2％和蜂王浆控油因子2％。
4.如权利要求1所述祛痘凝胶，其特征在于，所述祛痘凝胶还包含尿囊素、保湿剂、螯合剂、增稠剂和防腐剂。
5.如权利要求1所述祛痘凝胶，其特征在于，所述尿囊素在所述祛痘凝胶中的重量百分含量为0.1～0.2％。
6.如权利要求1所述祛痘凝胶，其特征在于，所述保湿剂包含1.3-丁二醇和透明质酸钠；所述1.3-丁二醇在所述祛痘凝胶中的重量百分含量为1～6％；所述透明质酸钠在所述祛痘凝胶中的重量百分含量为0.01～0.1％。
7.如权利要求1所述祛痘凝胶，其特征在于，所述螯合剂包含EDTA-2Na；所述增稠剂包含丙烯酸羟乙酯、丙烯酰二甲基牛磺酸钠共聚物的混合物、阿拉伯胶树胶和黄原胶的混合物；在所述祛痘凝胶中，所述EDTA-2Na的重量百分含量为0.02～0.1％；所述丙烯酸羟乙酯、丙烯酰二甲基牛磺酸钠共聚物的混合物的重量百分含量为0.8～1.8％；所述阿拉伯胶树胶和黄原胶的混合物的重量百分含量为0.1～0.5％；所述羟苯甲酯的重量百分含量为0.08～0.2％；所述苯氧乙醇、羟苯乙酯、羟苯甲酯和乙基己基甘油的混合物的重量百分含量为0.2～0.5％。
8.如权利要求1所述祛痘凝胶，其特征在于，所述祛痘凝胶由以下重量百分含量的组分：金缕梅提取物2～4％、小球藻提取物0.8～1.5％、肉豆蔻酰六肽-52～4％、硅烷二醇水杨酸酯1～3％、蜂王浆控油因子1～3％、尿囊素0.1～0.2％、1.3-丁二醇2～4％、透明质酸钠0.01～0.1％、EDTA-2Na 0.02～0.1％、丙烯酸羟乙酯和丙烯酰二甲基牛磺酸钠共聚物的混合物0.8～1.8％、阿拉伯胶树胶和黄原胶的混合物0.1～0.5％、羟苯甲酯0.08～0.2％、苯氧乙醇、羟苯乙酯、羟苯甲酯和乙基己基甘油的混合物0.2～0.5％、薰衣草精油0.01～0.05％和余量的水。
9.如权利要求1所述祛痘凝胶，其特征在于，所述祛痘凝胶由以下重量百分含量的组分：金缕梅提取物3％、小球藻提取物1％、肉豆蔻酰六肽-5 3％、硅烷二醇水杨酸酯2％、蜂王浆控油因子2％、尿囊素0.15％、1.3-丁二醇3％、透明质酸钠0.05％、EDTA-2Na 0.05％、丙烯酸羟乙酯和丙烯酰二甲基牛磺酸钠共聚物的混合物1.5％、阿拉伯胶树胶和黄原胶的混合物0.3％、羟苯甲酯0.1％、苯氧乙醇、羟苯乙酯、羟苯甲酯和乙基己基甘油的混合物0.35％、薰衣草精油0.02％和余量的水。
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