CN110227128A - A kind of outer wine and preparation method thereof of applying medicinal lotion or ointment - Google Patents
A kind of outer wine and preparation method thereof of applying medicinal lotion or ointment Download PDFInfo
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- CN110227128A CN110227128A CN201910452006.5A CN201910452006A CN110227128A CN 110227128 A CN110227128 A CN 110227128A CN 201910452006 A CN201910452006 A CN 201910452006A CN 110227128 A CN110227128 A CN 110227128A
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K31/12—Ketones
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- A61K31/125—Camphor; Nuclear substituted derivatives thereof
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention discloses wine of applying medicinal lotion or ointment outside one kind, and the white wine including bulk pharmaceutical chemicals and for impregnating bulk pharmaceutical chemicals, the bulk pharmaceutical chemicals include camphor, borneol, Radix Rehmanniae, Radix Notoginseng, safflower, dragon's blood, Moschus and Mentholum.The invention also discloses method for preparing medicated wine of applying medicinal lotion or ointment outside one kind, the following steps are included: S1: taking Radix Rehmanniae to be soaked in white wine and obtain rehmannia root wine, it takes Radix Notoginseng to be soaked in white wine and obtains pseudo-ginseng liquor, it takes safflower to be soaked in white wine and obtains safflower wine, it takes dragon's blood to be soaked in white wine and obtains dragon's blood wine, take Moschus to be soaked in white wine and obtain Moschus wine；S2: taking camphor and borneol to be dissolved with 95% alcohol, white wine be then added, and adds pseudo-ginseng liquor, safflower wine, Moschus wine, dragon's blood wine and rehmannia root wine, is eventually adding Mentholum, stirs evenly, and obtains outer wine solution of applying medicinal lotion or ointment；S3: it takes and applies medicinal lotion or ointment wine solution outside and rice vinegar is put into container with the ratio of 4:1, stir evenly, stored, storage a period of time rear can be used.
Description
Technical field
The present invention relates to liquid medicine technical fields, and in particular to a kind of outer wine and preparation method thereof of applying medicinal lotion or ointment.
Background technique
Drug is placed in alcohol or white wine and impregnates by liquid medicine.Wine is known as the title of " length of hundred medicines ", will keep fit and healthy
Chinese medicine and wine " molten " Yu Yiti liquid medicine, not only prepare that convenient, pharmacological property is stable, safely and effectively, but also because alcohol is a kind of
Good semi-polarity organic solvent, the various effective components of Chinese medicine are all soluble in wherein, and wine assisting drug, wine help medicine gesture and sufficiently sends out
Its effect is waved, curative effect is improved.
Liquid medicine is a kind of leaching preparation.I.e. dry vegetable drug or food, histocyte atrophy are each in cell liquid
Kind of ingredient by crystallize or amorphous sediment in a manner of be present in cell, need wine liquid as solvent to leach its effective component
It infiltrates medicinal material and enters among cell, followed by the performance good desorption of ethyl alcohol, dissolve its soluble component, be allowed to be transferred to molten
Among matchmaker.After solvent has dissolved many substances in the cell, Intracellular solution concentration is made to be significantly higher than extracellular and form concentration
Difference.This concentration difference is exactly leaned on, makes cell external diffusion of the intracellular high concentration leachate constantly to low concentration direction, while dilute
Solution constantly enters in crude drug cell again, is gradually dissolved in the soluble component in drug in wine.
Fall and flutter hurt, version of tendon and muscle bone is wrong, and extravasated blood accumulation, swell hard distending pain, injury of the tissues agglomeration, qi and blood retardance, and to the marrow, numbness is or not chill
Benevolence and articular instability are the disease pains that people frequently suffer from, mainly since QI-blood circulation is unsmooth, channels and collaterals are obstructed, body machine
Can decline causes, it is difficult to cure, once encountering rainy weather, somatosensory is more obvious.So how to provide one kind makes medicine
Effective component in object is penetrated into from outside, and Chinese medicine Zhuifengsan knot, activating blood circulation and reducing swelling, warm muscle is active, strengthens muscle analgesic, fundamentally to disease into
The outer wine cost of applying medicinal lotion or ointment of row treatment is those skilled in the art head technical problems to be solved.
Summary of the invention
The technical problem to be solved by the present invention is to how to provide one kind can Chinese medicine Zhuifengsan knot, activating blood circulation and reducing swelling, warm muscle is active,
Outer wine and preparation method thereof of applying medicinal lotion or ointment of strong muscle analgesic.
The technical scheme to solve the above technical problems is that a kind of outer wine of applying medicinal lotion or ointment, including bulk pharmaceutical chemicals and it is used for
The white wine of bulk pharmaceutical chemicals is impregnated, the bulk pharmaceutical chemicals include 85-170 parts of camphor, 2.5-5 parts of borneol, 125-250 parts of Radix Rehmanniae, Radix Notoginseng
15-30 parts, 25-50 parts of safflower, 15-30 parts of dragon's blood, 1-2 parts of Moschus and 12-24 parts of Mentholum.
Bulk pharmaceutical chemicals of the present invention, drug effect and pharmacology are as follows: camphor, [drug effect] is sensible, desinsection, analgesic,
Ward off dirty, [pharmacology] controls trusted subordinate's distending pain, tinea pedis, sore scabies, toothache, traumatic injury；Borneol, [drug effect] enter the heart, lung channel, lead to all
Key dissipates stagnated fire, goes screen improving eyesight, swelling and pain relieving, and [pharmacology] controls apoplexy lockjaw, pyreticosis coma, frightened epilepsy phlegm confusing heart, deafness with qi stagnation, sore throat,
Aphtha, tympanitis, carbuncle swells, hemorrhoid；Radix Rehmanniae, [drug effect] clearing heat and cooling blood, benefiting yin are promoted the production of body fluid [pharmacology] broken stasis of blood, raw new, analgesic, menstruation regulating,
The metal-inflicted wound stasis of blood, cool blood, hemostasis；Radix Notoginseng, [drug effect] enhancing immunity of organism, antitumor, balance adjustment blood cell are to promote blood
Cell metabolism, [pharmacology] expand blood vessel, increase blood flow, improve the hematopoiesis function of human body, have significant hemostatic function；
Safflower, [drug effect] blood circulation, removing blood stasis and acesodyne facilitate controlling through closing, dysmenorrhea, lochia, chest impediment and cardialgia, stasis of blood, chest
Shouting pain, traumatic injury, sore swell and ache curative curative effect are coerced, [pharmacology] has the effect of activating microcirculation and removing stasis medicinal, dissipate wet effect going to swell；Dragon's blood, [drug effect] have
The effect of scattered stasis pain, hemostasis, myogenic sore, [pharmacology] is the major functions: traumatic injury；Internal injury stasis caused pain；Dysmenorrhea；Postpartum stasis abdominal pain；
Traumatic hemorrhage is more than；Scrofula；Ulcer on the shank is burst not to be conformed to and hemorrhoid long；Moschus, [drug effect] property is pungent, warm, nontoxic, bitter, enters the heart, spleen, liver
There is the function of having one's ideas straightened out, ward off dirty, dredging collateral, scattered silt, [pharmacology] cures mainly apoplexy, coma due to blocking of the respiratory system, frightened epilepsy, middle evil unhappiness, trusted subordinate sudden and violent pain, falls
Play damage, swollen ulcer drug；Mentholum, [drug effect] antipruritic, analgesic and anti-inflammatory, and [pharmacology] is antipruritic, anti-inflammatory, analgesic, simultaneous with
Refrigerant sense.
Bulk pharmaceutical chemicals selected by the present invention, camphor, borneol, Radix Rehmanniae, Radix Notoginseng, safflower, dragon's blood, Moschus and Mentholum, section
Compatibility is learned, is acted synergistically between each drug, activating microcirculation and removing stasis medicinal, Chinese medicine Zhuifengsan knot, activating blood circulation and reducing swelling, the active and strong muscle analgesic of warm muscle are reached
Effect.In use, wiping wine of applying medicinal lotion or ointment outside in affected part, and it is massaged into absorption, so that outside liquid medicine is deep into affected part from outside to inside,
More conducively absorption of the affected part to effective component in bulk pharmaceutical chemicals.The effective component in bulk pharmaceutical chemicals is dissolved using white wine, it can be with
Preferably effective component is extracted, improves drug effect.It can while anti-inflammatory analgetic added with Mentholum in this bulk pharmaceutical chemicals
With antipruritic, refrigerant sense is brought, affected part there can be certain gargalesthesia when restoring, and in recovery process, expert is not grabbed, and scratch is outer
It applies medicinal lotion or ointment wine, can be antipruritic, simultaneous with refrigerant sense, make one to feel more comfortable.This outer wine of applying medicinal lotion or ointment, flutters hurt for falling, and version of tendon and muscle bone is wrong,
The case where extravasated blood accumulation, swell hard distending pain, and injury of the tissues agglomeration, qi and blood retardance, chill is to the marrow, apathetic, articular instability uses,
To reach activating microcirculation and removing stasis medicinal, promote blood circulation, the effect of swelling and pain relieving and promoting flow of qi by warming channel.
The invention also discloses method for preparing medicated wine of applying medicinal lotion or ointment outside one kind, which comprises the following steps:
S1: it takes 250 parts of Radix Rehmanniaes to be soaked in 1500 parts of white wine and obtains rehmannia root wine, 30 portions of Radix Notoginseng is taken to be soaked in 500 parts of white wine
In obtain pseudo-ginseng liquor, take 50 parts of safflowers to be soaked in 500 parts of white wine and obtain safflower wine, 30 parts of dragon's blood is taken to be soaked in 500 parts of white wine
In obtain dragon's blood wine, take 2 parts of Moschus to be soaked in 500 parts of white wine and obtain Moschus wine；
S2: taking 170 parts of camphors and 5 parts of borneols to be dissolved with 200 part 95% of alcohol, and 2000 parts of white wine are then added,
30 parts of pseudo-ginseng liquors, 30 parts of safflower wines, 30 portions of Moschus wine, 20 portions of dragon's blood wine and 400 parts of rehmannia root wines are added, are eventually adding 18
Part Mentholum, stirs evenly, and obtains outer wine solution of applying medicinal lotion or ointment；
S3: taking and apply medicinal lotion or ointment wine solution outside and rice vinegar is put into container with the ratio of 4:1, stir evenly, stored, storage one
Section time rear can be used.
Wherein, in step S3, storage time at least 1 year.
In this way, white wine is obtained as a kind of organic solvent first with soaking in Chinese liquor Radix Rehmanniae, Radix Notoginseng, safflower, dragon's blood and Moschus
It to rehmannia root wine, pseudo-ginseng liquor, safflower wine, dragon's blood wine and Moschus wine, finally mixes, can preferably be directed to every kind of different bulk pharmaceutical chemicals
Carry out the extraction of effective component.It adds camphor and borneol dissolves the solution in 95% alcohol, add Mentholum, obtain
To wine solution of applying medicinal lotion or ointment outside, finally mixes, stored with rice vinegar.It is rice vinegar basic amino acid rich in, glucide, organic
Acid, vitamin B1, vitamin B2, vitamin C, inorganic salts, minerals etc. can mix with wine solution of applying medicinal lotion or ointment outside, improve outer wipe
The drug effect of liquid medicine, while adjustable outer smells of wine of applying medicinal lotion or ointment.
Specific embodiment
The given examples are served only to explain the present invention, is not intended to limit the scope of the present invention.
Embodiment one: a kind of outer wine of applying medicinal lotion or ointment, the white wine including bulk pharmaceutical chemicals and for impregnating bulk pharmaceutical chemicals, the raw material pack
Include 170 parts of camphor, 5 parts of borneol, 250 parts of Radix Rehmanniae, 30 parts of Radix Notoginseng, 50 parts of safflower, 30 parts of dragon's blood, 2 parts of Moschus and Mentholum 18
Part.
The preparation method of above-mentioned outer wine of applying medicinal lotion or ointment is as follows, comprising the following steps:
S1: it takes 250 parts of Radix Rehmanniaes to be soaked in 1500 parts of white wine and obtains rehmannia root wine, 30 portions of Radix Notoginseng is taken to be soaked in 500 parts of white wine
In obtain pseudo-ginseng liquor, take 50 parts of safflowers to be soaked in 500 parts of white wine and obtain safflower wine, 30 parts of dragon's blood is taken to be soaked in 500 parts of white wine
In obtain dragon's blood wine, take 2 parts of Moschus to be soaked in 500 parts of white wine and obtain Moschus wine；
S2: taking 170 parts of camphors and 5 parts of borneols to be dissolved with 200 part 95% of alcohol, and 2000 parts of white wine are then added,
30 parts of pseudo-ginseng liquors, 30 parts of safflower wines, 30 portions of Moschus wine, 20 portions of dragon's blood wine and 400 parts of rehmannia root wines are added, are eventually adding 18
Part Mentholum, stirs evenly, and obtains outer wine solution of applying medicinal lotion or ointment；
S3: taking and apply medicinal lotion or ointment wine solution outside and rice vinegar is put into container with the ratio of 4:1, stir evenly, stored, storage one
Section time rear can be used.
Wherein, in step S3, storage time 1 year.
Embodiment two:
A kind of outer wine of applying medicinal lotion or ointment, the white wine including bulk pharmaceutical chemicals and for impregnating bulk pharmaceutical chemicals, the bulk pharmaceutical chemicals include camphor 100
Part, 4 parts of borneol, 200 parts of Radix Rehmanniae, 20 parts of Radix Notoginseng, 40 parts of safflower, 20 parts of dragon's blood, 1.5 parts of Moschus and 15 parts of Mentholum.
Embodiment three:
A kind of outer wine of applying medicinal lotion or ointment, the white wine including bulk pharmaceutical chemicals and for impregnating bulk pharmaceutical chemicals, the bulk pharmaceutical chemicals include camphor 130
Part, 3 parts of borneol, 150 parts of Radix Rehmanniae, 25 parts of Radix Notoginseng, 30 parts of safflower, 15 parts of dragon's blood, 1 part of Moschus and 10 parts of Mentholum.
Application method: 2-3 times daily, affected part is smeared, and ten days as a course for the treatment of, three course for the treatment of recoveries from illness.
Clinical effectiveness:
Patient Mr. Wang, age 43, arthralgia, especially especially severe rainy days are applied medicinal lotion or ointment outside using provided by the invention
Wine smears affected part, and 3 times a day, pain is substantially reduced after ten days, and rainy days, pain was substantially reduced, basic rehabilitation after 20 days, and three
It fully recovers after ten days, no relapse.
The foregoing is merely presently preferred embodiments of the present invention, is not intended to limit the invention, it is all in spirit of the invention and
Within principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (3)
1. a kind of outer wine of applying medicinal lotion or ointment, which is characterized in that the white wine including bulk pharmaceutical chemicals and for impregnating bulk pharmaceutical chemicals, the raw material pack
Include 85-170 parts of camphor, 2.5-5 parts of borneol, 125-250 parts of Radix Rehmanniae, 15-30 parts of Radix Notoginseng, 25-50 parts of safflower, 15-30 parts of dragon's blood,
1-2 parts of Moschus and 12-24 parts of Mentholum.
2. a kind of outer method for preparing medicated wine of applying medicinal lotion or ointment, which comprises the following steps:
S1: taking 250 parts of Radix Rehmanniaes to be soaked in 1500 parts of white wine and obtain rehmannia root wine, takes 30 portions of Radix Notoginseng to be soaked in 500 parts of white wine and obtains
It to pseudo-ginseng liquor, takes 50 parts of safflowers to be soaked in 500 parts of white wine and obtains safflower wine, take 30 parts of dragon's blood to be soaked in 500 parts of white wine and obtain
To dragon's blood wine, takes 2 parts of Moschus to be soaked in 500 parts of white wine and obtain Moschus wine；
S2: taking 170 parts of camphors and 5 parts of borneols to be dissolved with 200 part 95% of alcohol, then 2000 parts of white wine of addition, then plus
Enter 30 parts of pseudo-ginseng liquors, 30 parts of safflower wines, 30 portions of Moschus wine, 20 portions of dragon's blood wine and 400 parts of rehmannia root wines, is eventually adding 18 portions of peppermints
Ice stirs evenly, and obtains outer wine solution of applying medicinal lotion or ointment；
S3: it takes and applies medicinal lotion or ointment wine solution outside and rice vinegar is put into container with the ratio of 4:1, stir evenly, stored, when storing one section
Between rear can be used.
3. outer method for preparing medicated wine of applying medicinal lotion or ointment as claimed in claim 2, which is characterized in that in step S3, storage time at least 1 year.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112220874A (en) * | 2020-10-30 | 2021-01-15 | 四川省骨科医院 | External traditional Chinese medicine composition and preparation method and application thereof |
| CN113144064A (en) * | 2021-04-12 | 2021-07-23 | 成都体育学院 | Wine for treating wind-cold invading muscles and bones and preparation method thereof |
| CN113940987A (en) * | 2021-10-13 | 2022-01-18 | 易冬 | Traditional Chinese medicine liquor for treating bone fracture and preparation method thereof |
-
2019
- 2019-05-28 CN CN201910452006.5A patent/CN110227128A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 宋万华等主编: "《中西医结合治疗软组织损伤》", 31 July 2010, 吉林电子出版社 * |
| 张天锦: "自拟药酒治疗软组织损伤180例", 《中医外治杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112220874A (en) * | 2020-10-30 | 2021-01-15 | 四川省骨科医院 | External traditional Chinese medicine composition and preparation method and application thereof |
| CN113144064A (en) * | 2021-04-12 | 2021-07-23 | 成都体育学院 | Wine for treating wind-cold invading muscles and bones and preparation method thereof |
| CN113940987A (en) * | 2021-10-13 | 2022-01-18 | 易冬 | Traditional Chinese medicine liquor for treating bone fracture and preparation method thereof |
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