CN110218629A - A kind of kit for hereditary tumor genetic test - Google Patents
A kind of kit for hereditary tumor genetic test Download PDFInfo
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- CN110218629A CN110218629A CN201910563869.XA CN201910563869A CN110218629A CN 110218629 A CN110218629 A CN 110218629A CN 201910563869 A CN201910563869 A CN 201910563869A CN 110218629 A CN110218629 A CN 110218629A
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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Abstract
The invention discloses a kind of kits for hereditary tumor genetic test, are related to kit technical field.This is used for the kit of hereditary tumor genetic test, including box body, support plate is fixedly connected in the box body, and four sides of support plate are plugged on respectively in four sides of inboard wall of cartridge, water storage case is provided with below support plate, and the bottom of water storage case is fixedly connected on the left side of bottom in box body, the top on the left of water storage case is plugged with the water inlet pipe being connected to itself inner cavity, and water inlet pipe runs through the left side of box body far from one end of water storage case.This is used for the kit of hereditary tumor genetic test, heat mechanism is used by pressing reset button, on the annular sponge in water body heating heel row to hollow in water storage case, after annular sponge water swelling with solvent bottle intimate surface contact, so that water temperature is conducted via solvent bottle to solvent, solvent is heated, so that since the sediment of the lower precipitation of solvent temperature gradually melts.
Description
Technical field
The present invention relates to kit technical field, specially a kind of kit for hereditary tumor genetic test.
Background technique
It is since genetic oncogene is not examined effectively in the early stage mostly in the family with cancer family's medical history
It measures, is delayed so as to cause treatment time, the death rate of cancer is high.For this hereditary tumor, domestic and international base
This use heredity oncogene detection technique effectively detect and contain in time in state of an illness incubation period, passes through and acquire subject's
Saliva sample simultaneously extracts wherein DNA, quickly and clearly can judge whether subject carries using high-throughput gene sequencer
Hereditary tumor gene.The kit used in this step is DNA extraction kit, and this kit is substantially by five kinds of reagents
Bottle composition: saving liquid, cell pyrolysis liquid, contamination precipitation liquid, DNA lysate and 5ml collection tube, in order to guarantee sample activity, leads to
The mode of refrigeration is taken to store in the case where detection cannot often be executed at once after acquisition, it is molten in kit when temperature is lower
Liquid will will appear the case where partly precipitated is precipitated, and warming-in-water need to be carried out when using solution, sediment is melted, while being melted
Needing for solution to be cooled to room temperature after change can use, and such use pattern reduces the entirety of detection work to a certain extent
Working efficiency.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of kit for hereditary tumor genetic test,
User, which need to use when solution, can be immediately performed heating and cooling step, it is ensured that quickly reach while in solution without containing precipitating
To usable condition.
In order to achieve the above object, the present invention is achieved by the following technical programs: one kind being used for hereditary tumor gene
The kit of detection, including box body are fixedly connected with support plate in the box body, and four sides of support plate are plugged on box body respectively
In four sides of inner wall, water storage case is provided with below support plate, and the bottom of water storage case is fixedly connected on a left side for bottom in box body
Side, the top on the left of water storage case is plugged with the water inlet pipe being connected to itself inner cavity, and water inlet pipe runs through far from one end of water storage case
The left side of box body is plugged with sealing-plug in the left end of water inlet pipe, and the left side at the top of water storage case is fixedly installed with heat mechanism, and stores up
Middle part at the top of water box is fixedly connected with the catch tray being connected to itself inner cavity, and the middle part at the top of catch tray is plugged with gas-guide tube
One end, and the one end of gas-guide tube far from catch tray extends to the right along the bottom of support plate and is fixedly connected with handle box.
The bottom of handle box is fixedly connected on the right side of bottom in box body, and is fixedly installed with collection on the left of the inner cavity of handle box
Gas driving mechanism is movably installed with driving member in the middle part of rear wall bottom in handle box, and is movably installed with unfreezing machine on driving member
Structure, the upper half of defrosting mechanism is fixedly mounted on the right side at the top of support plate, and is fixedly connected on the right side of the defrosting mechanism upper half
There is one end of exhaust part, the other end of exhaust part runs through the right side of box body, and the right side of water storage case passes through aqueduct and micro pump
Water inlet be connected to and in communication with, and the water outlet of micro pump is connect with water delivery mechanism, and the lower portion of water delivery mechanism is in support
In plate, and the upper half of water delivery mechanism extends to the top of defrosting mechanism.
Preferably, the inner cavity of the catch tray is up-narrow and down-wide shape, and catch tray inner wall is close to the side of water storage case inner cavity
Splicing has the ventilative film that blocks water, and such structure design promotes steam to gather, while avoiding water body from entering by the ventilative film that blocks water and leading
Tracheae.
Preferably, the heat mechanism includes that reset button, placing frame, filter, storage capsule and stamp needle, reset button are lateral
It is interspersed to be connected in the left wall of box body, and the right end of reset button is plugged in the left side of placing frame, the top of placing frame is fixed
It is connected to the left side of support plate bottom, the left side of water storage case inner top is run through in the bottom of placing frame, and four sides of filter are fixed respectively
It is connected to the bottom of four side of placing frame inner wall, button is fixedly connected with stamp needle close to one end of placing frame in reset button, and stabs
Needle runs through the inner left wall of placing frame far from one end of reset button, and storage capsule is in swelling state, and store it is intracapsular be filled with 500~
1000 milligrams of quick lime, water and the proportion of quick lime are 100:1 in water storage case, and the unit of water is milliliter, and box body is just
Face is hinged with folding piece, and opens and closes the front side that piece runs through fixed frame.
Preferably, the gas collection driving mechanism include fixed cylinder, extension airbag, connector, diaphragm seal, stabiliser bar, port,
Connecting tube, connecting cylinder and appendix are fixedly connected on the left side of handle box inner top, the top of extension airbag at the top of fixed cylinder
It is fixedly connected on the left side of handle box inner top, and the side surface of extension airbag and the inner wall of fixed cylinder fit closely, connector
It is fixedly connected on the middle part of extension airbag bottom and is connected to the inner cavity of extension airbag, the quantity of diaphragm seal is four, and four
The side surface of diaphragm seal contacts with each other and closes the inner cavity of connector, and stabiliser bar is respectively welded at the left and right sides of connector, leads to
Mouth is provided with the bottom of fixed cylinder and is connected to its inner cavity, and connecting tube is disposed longitudinally in port, and connecting cylinder is in longitudinal solid respectively
Surely it is connected to the left and right sides of connecting tube, the front and rear sides of connecting cylinder are fixed with the bottom of port inner wall front and rear sides respectively to be connected
It connects, the bottom end of two stabiliser bars extends through two connecting cylinders and runs through the bottom end of connecting cylinder, the inner wall and connecting tube of connector
Outer diameter mutually agree with, and the central axes of connector are overlapped with the central axes of connecting tube, and one end of appendix passes through flange plate
It is sleeved on the bottom end of connecting tube, and the inner cavity of appendix is connected to the inner cavity of connecting tube, ensure that connector can be with after moving down
Connecting tube is adapted the case where being connected to, avoiding gas leakage appearance, and simultaneous retractable air bag just can band after saving bit by bit enough steam
Dynamic connector is connect with connecting tube, it is ensured that active force when gas is discharged can drive semicircle part to operate.
Preferably, the driving member includes turntable and inclined tab, and turntable is movably connected in place by interting pin shaft in the center point
On the interior rear wall for managing box, and turntable is located at the right side of appendix right end, and inclined tab, which obliquely and equidistantly surround to be fixedly connected on, to be turned
The front of disk, positioned at inclined tab frontal left inclined tab close to appendix right end so that appendix exhaust when necessarily to inclined tab
Horizontal cross force is imposed, its stress is made by the skewed design of inclined tab and turntable is driven to rotate.
Preferably, the defrosting mechanism includes hollow, stop collar, annular sponge, drive rod, semicircle part, brace, connection
Bar and slide guide item, hollow are fixedly connected on the rightmost side at the top of support plate, and the outer ring of stop collar is fixedly connected on hollow
On inner wall, the bottom of annular sponge is fixedly connected on the top of stop collar, and the quantity of drive rod is two, and two drive rods are in
Longitudinal direction is respectively interposed in the left and right sides at the top of annular sponge, and the bottom of support plate is run through in the bottom end of two drive rods, limit
Through-hole compatible with drive rod is offered in the ring of position, semicircle part is threaded in the top of two drive rods in symmetry shape, and
The top of two drive rods is opposite to be bent, and the bottom end of two drive rods is hinged with two braces in symmetry shape, and two braces
One end of phase seatback drive link passes through the top that pin shaft is hinged on connecting rod, and the rear side of connecting rod and fixed company is arranged in slide guide item
It connects on the interior rear wall of handle box, and the front of slide guide item offers guide runner, after the pin shaft that brace and connecting rod hingedly use
End is slidably connected in guide runner, and the bottom end of connecting rod is hinged on the positive top of turntable, and connecting rod, brace and drive rod will
In heat transfer to annular sponge cooperate defrosting work carry out, while by drive rod drive semicircle part operate to annular sponge into
Row repeatedly extrudes, and such working method cooperation annular sponge further reaches defrosting effect.
Preferably, the water delivery mechanism includes general pipeline, T shape pipe, bending tube, ring pipe and scupper, the bottom end of general pipeline with
The water outlet of micro pump is connected to and in communication with, and the top of general pipeline is plugged in the bottom of support plate, and T shape pipe is laterally inlaid in branch
In fagging, and the left end of T shape pipe and the top on the right side of general pipeline are welded, and the bottom end of bending tube is welded on longer one section of the top of T shape pipe
The top in portion, bending tube runs through the top of support plate and extends to the top of hollow, and the left side of ring pipe and bending tube are shorter
One section of welding, scupper is in being equidistantly provided with the bottom of ring pipe and be connected to the inner cavity of ring pipe, general pipeline, T shape around shape
The inner cavity of pipe, bending tube and ring pipe is interconnected, and making each solvent bottle by diversion design can normally be solved
Freeze effect, scupper ensure that annular sponge each section uniform water absorption around the design of shape and orderly expand, and carry out to solvent bottle
Defrosting processing.
Preferably, the drainage element includes drainpipe and swelling bag, and drainpipe is laterally interspersed in the right wall of box body, and is arranged
Bottom of the left end of water pipe on the right side of the hollow is simultaneously connected to the inner cavity of hollow, and swelling bag is glued to the inner wall of drainpipe,
Swelling bag is made of expanding with heat and contract with cold material, and circulate box body inner air and outer air under non-working condition, and self-closed guarantees to thaw when use
The normal implementation of function.
The present invention provides a kind of kits for hereditary tumor genetic test.Have it is following the utility model has the advantages that
(1), the kit for being used for hereditary tumor genetic test heats water body by chemical reaction, and water temperature is via molten
Agent bottle bottle body is conducted into liquid in bottle, is accelerated genetic test working efficiency, while reaching defrosting effect, is reacted the heat of generation
Steam spreads in box body and plays auxiliary defrosting effect to other reagents, thaws for the solvent bottle for being easy to produce precipitating
While, the defrosting effect of hot steam is relatively slow, it is therefore prevented that other reagents being without the use of thaw very fast in non-service stage
The case where influencing its quality appearance.
(2), the kit for being used for hereditary tumor genetic test thaws to solvent bottle in heating water body same
When, the synchronous driving defrosting mechanism of the hot steam that water body is released squeezes sponge, will be located in the middle part of sponge and far from solvent
During the side of bottle presses to solvent bottle, moisture extrusion is further contacted into the water for thawing, while squeezing out with solvent bottle
Volume, which is collected together, carries out immersion defrosting to the position for easily generating precipitating in solvent bottle in hollow, and defrosting mechanism is in operation
Temperature is imported in annular sponge via the mode of contact equally, certain supplementary result is played to its temperature, is further ensured that molten
The defrosting effect of agent.
(3), the kit for being used for hereditary tumor genetic test can be protected in the kit refrigeration stage by drainage element
Hold the circulation of kit inner air and outer air, it is ensured that cold air, which rapidly enters, cools down to reagent and solvent in kit, in kit solution
Freeze and drainage element is closed by hot water when using, it is ensured that the bottom that solvent bottle is easy to produce precipitating obtains the defrosting of hot-water soak always
Effect, while drainage element can carry out the job step that solvent is cooled to room temperature in the moment discharge hot water and hot gas that heating effect terminates
Suddenly.
(4), kit for being used for hereditary tumor genetic test, by using annular sponge as heat-conducting medium, energy
Enough that the water body of absorption is effectively divided into two parts storage, a part is, close to the side of solvent bottle, which takes the lead in and is in low
The solvent bottle surface contact of temperature, wherein the heat of water body takes the lead in being conducted in solvent bottle, and such heating method avoids entirely
Portion's heat disposably by solvent bottle Surface absorption, causes solvent bottle surface although to be thawed, but internal precipitate is not received and filled
The case where sufficient heat thaws occurs, and can be avoided the water body of higher temperature and solvent bottle surface and directly contact causes solvent bottle to break
The case where splitting appearance cooperates repeatedly extruding for semicircle part during repeating to absorb water water storage, so that the hot water in annular sponge
Continue to contact with solvent bottle in continuous state, while cold water synchronizes and is discharged into hollow bottom, ensure that solvent bottle surface is held
Continuous heating effect, defrosting work is completed and starts to cool down when final whole water body is discharged into hollow, and secondary solvent bottle enters cold
But the stage.
Detailed description of the invention
Fig. 1 is structure of the invention cross-sectional view；
Fig. 2 is structure of the invention perspective view；
Fig. 3 is schematic enlarged-scale view at the A in Fig. 1 of the present invention；
Fig. 4 is schematic enlarged-scale view at the B in Fig. 1 of the present invention；
Fig. 5 is the perspective view that direction is looked up by water delivery mechanism of the present invention；
Fig. 6 is the perspective view of driving member of the present invention；
Fig. 7 is the side view of drainage element of the present invention.
In figure: 1 box body, 2 support plates, 3 water storage cases, 4 water inlet pipes, 5 sealing-plugs, 6 heat mechanisms, 7 catch trays, 8 ventilative resistances
It is moisture film, 9 gas-guide tubes, 10 handle boxes, 11 driving mechanisms, 12 driving members, 13 defrosting mechanisms, 14 drainage elements, 15 micro pumps, 16 defeated
Water dispenser structure, 17 folding pieces, 601 reset button, 602 placing frames, 603 filters, 604 storage capsules, 605 stamp needles, 111 fixed cylinders, 112
Extension airbag, 113 connectors, 114 diaphragm seals, 115 stabiliser bars, 116 ports, 117 connecting tubes, 118 connecting cylinders, 119 appendixs,
121 turntables, 122 inclined tab, 131 hollows, 132 stop collars, 133 annular sponges, 134 drive rods, 135 semicircle parts, 136 braces,
137 connecting rods, 138 slide guide items, 161 general pipeline, 162T shape pipes, 163 bending tubes, 164 ring pipes, 165 scuppers, 141 drainpipes,
142 swelling bags.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
Examples of the embodiments are shown in the accompanying drawings, and in which the same or similar labels are throughly indicated identical or classes
As element or element with the same or similar functions.The embodiments described below with reference to the accompanying drawings are exemplary, purport
It is being used to explain the present invention, and is being not considered as limiting the invention.
Fig. 1-7 is please referred to, the present invention provides a kind of technical solution: a kind of reagent for hereditary tumor genetic test
Box, including box body 1 are fixedly connected with support plate 2 in box body 1, and four sides of support plate 2 are plugged on the four of 1 inner wall of box body respectively
In side, the inner top of box body 1, support are run through in the bottom end that the top of box body 1 offers placement mouth in eight column-shaped of the five-element, and places mouth
The top of plate 2 offers eight column-shaped of the five-element corresponding with mouth is placed on box body 1 and places mouth, the placement mouth positioned at rightmost side side
Diameter is larger, and for placing solution bottle, the lower section of support plate 2 is provided with water storage case 3, and the bottom of water storage case 3 is fixedly connected
The top in the left side of bottom in box body 1,3 left side of water storage case is plugged with the water inlet pipe 4 being connected to itself inner cavity, and water inlet pipe 4
The left side of box body 1 is run through in one end far from water storage case 3, and sealing-plug 5, the left side at 3 top of water storage case are plugged in the left end of water inlet pipe 4
Side is fixedly installed with heat mechanism 6, and the middle part at 3 top of water storage case is fixedly connected with the catch tray 7 being connected to itself inner cavity, receives
The middle part at 7 top of catch basin is plugged with one end of gas-guide tube 9, and the one end of gas-guide tube 9 far from catch tray 7 is along the bottom of support plate 2
Portion extends to the right to be fixedly connected with handle box 10.
The bottom of handle box 10 is fixedly connected on the right side of bottom in box body 1, and fixed peace on the left of the inner cavity of handle box 10
Equipped with gas collection driving mechanism 11, driving member 12 is movably installed in handle box 10 in the middle part of rear wall bottom, and living on driving member 12
Dynamic to be equipped with defrosting mechanism 13, the upper half of defrosting mechanism 13 is fixedly mounted on the right side at 2 top of support plate, and defrosting mechanism 13
One end of drainage element 14 is fixedly connected on the right side of the upper half, the other end of drainage element 14 runs through the right side of box body 1, water storage case 3
Right side be connected to and in communication with by the water inlet of aqueduct and micro pump 15, and the water outlet of micro pump 15 and water delivery mechanism
16 connections, the lower portion of water delivery mechanism 16 is in support plate 2, and the upper half of water delivery mechanism 16 extends to defrosting mechanism 13
Top, the inner cavity of catch tray 7 is up-narrow and down-wide shape, and side splicing of 7 inner wall of catch tray close to 3 inner cavity of water storage case has ventilative resistance
Moisture film 8.
Heat mechanism 6 includes reset button 601, placing frame 602, filter 603, storage capsule 604 and stamp needle 605, and reset is pressed
Button 601 is laterally interspersed to be connected in the left wall of box body 1, and the right end of reset button 601 is plugged in the left side of placing frame 602,
The top of placing frame 602 is fixedly connected on the left side of 2 bottom of support plate, and the bottom of placing frame 602 is through 3 inner top of water storage case
Left side, four sides of filter 603 are respectively fixedly connected with the bottom in 602 inner wall of placing frame, four side, and button is close in reset button 601
One end of placing frame 602 is fixedly connected with stamp needle 605, and stabs needle 605 and run through placing frame 602 far from one end of reset button 601
Inner left wall, the front of box body 1 be hinged with folding piece 17, and open and close piece 17 run through fixed frame 601 front side, storage capsule 604 be in
Swelling state, and 500~1000 milligrams of quick lime is filled in storage capsule 604, the proportion of water and quick lime in water storage case 3
Unit for 100:1, water is milliliter, which is the rational proportion obtained by test of many times, it is ensured that reaction temperature will not
Excessively high the case where causing kit to damage appearance, the front of box body 1 are hinged with folding piece 17, and open and close piece 17 and run through placing frame
Disposable storage capsule 604 is replaced by opening folding piece 17 in 602 front side.
Gas collection driving mechanism 11 includes fixed cylinder 111, extension airbag 112, connector 113, diaphragm seal 114, stabiliser bar
115, port 116, connecting tube 117, connecting cylinder 118 and appendix 119, the top of fixed cylinder 111 are fixedly connected on handle box 10
The left side of inner top, the top of extension airbag 112 are fixedly connected on the left side of 10 inner top of handle box, and extension airbag 112
Side surface and the inner wall of fixed cylinder 111 fit closely, connector 113 be fixedly connected on the middle part of 112 bottom of extension airbag and with
The inner cavity of extension airbag 112 is connected to, and the quantity of diaphragm seal 114 is four, and the side surface of four diaphragm seals 114 contacts with each other simultaneously
The inner cavity of connector 113 is closed, stabiliser bar 115 is respectively welded at the left and right sides of connector 113, and port 116 is provided with fixation
The bottom of cylinder 111 is simultaneously connected to its inner cavity, and connecting tube 117 is disposed longitudinally in port 116, and connecting cylinder 118 is in longitudinal solid respectively
Surely it is connected to the left and right sides of connecting tube 117, the front and rear sides of connecting cylinder 118 bottom with 116 inner wall front and rear sides of port respectively
Portion is fixedly connected, and the bottom end of two stabiliser bars 115 extends through two connecting cylinders 118 and runs through the bottom end of connecting cylinder 118, connection
First 113 inner wall and the outer diameter of connecting tube 117 mutually agree with, and the central axes of the central axes of connector 113 and connecting tube 117
It is overlapped, such structure design ensures that connector 113 can match after moving down with connecting tube 117 and connects, while by steady
Fixed pole 115 and the cooperation of connecting cylinder 118 can effectively ensure that the movement routine of connector 113 is fixed, and one end of appendix 119 is logical
The bottom end that flange plate is sleeved on connecting tube 117 is crossed, and the inner cavity of appendix 119 is connected to the inner cavity of connecting tube 117.
Driving member 12 includes turntable 121 and inclined tab 122, and turntable 121 is movably connected in place by interting pin shaft in the center point
On the interior rear wall for managing box 10, and turntable 121 is located at the right side of 119 right end of appendix, and inclined tab 122 is oblique and equidistantly around solid
Surely be connected to the front of turntable 121, positioned at 122 frontal left of inclined tab inclined tab 122 close to appendix 119 right end, it is skewed
Inclined tab 122 ensure when turntable 121 is blown by air-flow in rotationally clockwise.
Defrosting mechanism 13 include hollow 131, stop collar 132, annular sponge 133, drive rod 134, semicircle part 135, tiltedly
Bar 136, connecting rod 137 and slide guide item 138, hollow 131 are fixedly connected on the rightmost side at 2 top of support plate, stop collar 132
Outer ring is fixedly connected on the inner wall of hollow 131, and the bottom of annular sponge 133 is fixedly connected on the top of stop collar 132, is passed
The quantity of lever 134 is two, and two drive rods 134 are respectively interposed in longitudinal in the left and right sides at 133 top of annular sponge
Interior, the bottom of support plate 2 is run through in the bottom end of two drive rods 134, offers in stop collar 132 and is adapted with drive rod 134
Through-hole, semicircle part 135 is threaded in the tops of two drive rods 134, and the top phase of two drive rods 134 in symmetry shape
To bending, the bottom end of two drive rods 134 is hinged with two braces 136 in symmetry shape, and two 136 phase seatback drive links of brace
134 one end passes through the top that pin shaft is hinged on connecting rod 137, and the rear side of connecting rod 137 and fixation is arranged in slide guide item 138
It is connected on the interior rear wall of handle box 10, and the front of slide guide item 138 offers guide runner, brace 136 and connecting rod 137 are hinged
The pin shaft rear end used is slidably connected in guide runner, and the bottom end of connecting rod 137 is hinged on the positive top of turntable 121, molten
Liquid bottle is located in hollow 131 after being put into box body 1, and sliding slot compatible with drive rod 134 is offered in annular sponge 133,
The bottom of 10 inner right wall of handle box is laterally interspersed with exhaust pipe, and the right end of exhaust pipe runs through the right side of box body 1 and connects with outside
It is logical, so as to which the hot gas in handle box 10 to be discharged, excessive the case where causing handle box 10 the to damage appearance of pressure is avoided, is based on
The physical rules of the upward ascension of thermal current are received when water body is reacted with quick lime in water storage case 3 via the hot steam of liquid table discharge
Catch basin 7 is collected to be discharged into extension airbag 112 via gas-guide tube 9 simultaneously, passes through the special designing of the film 8 that blocks water ventilative in catch tray 7
So that catch tray 7 only collects gas molecule without sucking hydrone, it is ensured that hot water fully enters in defrosting mechanism 13 to easy production
The solvent of raw precipitating is carried out for thawing, and simultaneous retractable air bag 112 is expanded and driven downwards in the state of being constantly filled with hot gas
Connector 113 is connect with connecting tube 117, and hot gas is discharged via appendix 119 when being released and connects to 121 surface of turntable
Inclined tab 122 generate thrust to drive turntable 121 rotate, turntable 121 rotate after drive connecting rod 137 top along slide guide
Item 138 back and forth moves up and down, and further pulls on drive rod 134 by brace 136 and back and forth moves up and down, so that semicircle part
135, which make reciprocal move up and down, squeezes the annular sponge 133 after water suction, and annular sponge 133 is further in extrusion process
It is contacted with solvent bottle surface and the lateral aperture for causing annular sponge 133 to contact with solvent bottle based on deformation effects becomes larger, be discharged
The water body saved bit by bit in annular sponge 133, further speeds up the Thawing Rate of solvent, at the same the water body squeezed out along solvent bottle surface to
Lower flowing is simultaneously saved bit by bit in the intracavity bottom of hollow 131, so that the solvent bottle bottom for generating precipitating is in the immersion of hot water always
In, reach and has targetedly removed sedimentation effect.
Water delivery mechanism 16 includes general pipeline 161, T shape pipe 162, bending tube 163, ring pipe 164 and scupper 165, general pipeline 161
Bottom end and the water outlet of micro pump 15 be connected to and in communication with, and the top of general pipeline 161 is plugged in the bottom of support plate 2, T shape
Pipe 162 is laterally inlaid in support plate 2, and the top on 161 right side of the left end of T shape pipe 162 and general pipeline is welded, bending tube 163
Bottom end is welded on longer one section of the top of T shape pipe 162, and the top of bending tube 163 is run through the top of support plate 2 and extended to hollow
The top of cylinder 131, the one section welding shorter with bending tube 163 of the left side of ring pipe 164, scupper 165 are opened in equidistant around shape
It is located at the bottom of ring pipe 164 and is connected to the inner cavity of ring pipe 164, general pipeline 161, T shape pipe 162, bending tube 163 and ring pipe
164 inner cavity is interconnected, and the top of T shape pipe 162 is equidistantly welded with five groups of bending tubes 163 and ring pipe 164, and solution bottle position
In in ring pipe 164, scupper 165 is located at the surface of annular sponge 133, and user is when needing using solvent, by pressing
Reset button 601 is pressed to use heat mechanism 6, the water body in water storage case 3 is pumped into defeated by the running of micro pump 15 after heating
In water dispenser structure 16 and drain on the annular sponge 133 in hollow 131, after 133 water swelling of annular sponge with solvent bottle surface
Be in close contact so that water temperature is conducted via solvent bottle to solvent, solvent is heated so that due to solvent temperature compared with
The sediment of low precipitation gradually melts, while the heat that water body is constantly reacted with quick lime in water storage case 3 during discharges is steamed
Vapour is equally discharged via water delivery mechanism 16, and the hot steam spread between 1 inner top of box body and support plate 2 can assisted effectively
Solvent bottle heating assists other reagents to thaw while melting sediment, it is ensured that the kit after Refrigerated Transport can use
When quick-thawing reach the usable condition of reagent, accelerate the working efficiency of genetic test work.
Drainage element 14 includes drainpipe 141 and swelling bag 142, and drainpipe 141 is laterally interspersed in the right wall of box body 1, and
The left end of drainpipe 141 is run through the bottom on 131 right side of hollow and is connected to the inner cavity of hollow 131, and swelling bag 142 is glued to
The inner wall of drainpipe 141, when starting to save bit by bit hot water in hollow 131, the Position Design based on drainpipe 141 flows into hot water
In drainpipe 141, swelling bag 142 with after hot water contacts at once expand and 141 inner cavity of drainpipe is closed, it is ensured that subsequent
Constantly being filled with hot water during hot water can save bit by bit in hollow 131, when water body in water storage case 3 and quick lime end of reaction
When water temperature start to be gradually reduced, restore original shape after swelling bag 142 is no longer heated and make water body via drainpipe 141
Box body 1 is discharged.
In use, pressing reset button 601 drives stamp needle 605 to move right to poking storage capsule 604 in placing frame 602,
Quick lime is fallen into water storage case 3 via filter 603 to react with water body, and hot water works via micro pump 15 to be pumped into aqueduct and pass through
It crosses general pipeline 161, T shape pipe 162, bending tube 163, ring pipe 164 and scupper 165 to drain into annular sponge 133, annular sponge
133 water swellings and contacting with solution bottle surface make the raising of its temperature start to melt sediment, water body and quick lime reaction process
The hot steam of middle production is discharged into extension airbag 112 via catch tray 7 and gas-guide tube 9, and extension airbag 112 is along fixed cylinder 111
Inner cavity expand downwards and connector 113 driven to move down, connector 113 is downward along connecting cylinder 118 by stabiliser bar 115
It is mobile, on 113 sets of connector to connecting tube 117, diaphragm seal 114 is squeezed by connecting tube 117, so that hot gas circulates and via defeated
Tracheae 119 sprays to inclined tab 122, so that turntable 121 as axis rotation and drives 137 bottom end of connecting rod to circle using pin shaft,
So that the pin shaft that connecting rod 137 is hingedly used with brace 136 back and forth moves up and down along slide guide item 138, the synchronous fortune of brace 136
It moves and drive rod 134 is driven to move synchronously, annular sponge 133 is squeezed so that semicircle part 135 moves synchronously, by annular sea
Water body in silk floss 133, which is squeezed out and further contacted with solution bottle surface, makes its heating, and the water body of extrusion is saved bit by bit in hollow 131
Intracavity bottom carries out hot water water-bath, part hot water when starting to save bit by bit hot water to the solution bottle bottom that sediment is saved bit by bit is easy to produce
Stream enters in drainpipe 141 and contacting with swelling bag 142 makes its expanded by heating close drainpipe 141, completes heating and starts to cool down
When swelling bag 142 shrink and box body 1 be discharged in water body, replace disposable storage capsule 604 by opening folding piece 17.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (8)
1. a kind of kit for hereditary tumor genetic test, including box body (1), it is characterised in that: in the box body (1)
It is fixedly connected with support plate (2), and four sides of support plate (2) are plugged on respectively in four sides of box body (1) inner wall, support plate (2)
Lower section be provided with the water storage case (3) with heat insulation effect, and the bottom of water storage case (3) is fixedly connected on box body (1) interior bottom
Left side, the top on the left of water storage case (3) is plugged with the water inlet pipe (4) being connected to itself inner cavity, and water inlet pipe (4) is far from water storage
The left side of box body (1) is run through in one end of box (3), is plugged with sealing-plug (5) in the left end of water inlet pipe (4), at the top of water storage case (3)
Left side is fixedly installed with heat mechanism (6), and the middle part at the top of water storage case (3) is fixedly connected with the collection being connected to itself inner cavity
Disk (7), the middle part at the top of catch tray (7) are plugged with one end of gas-guide tube (9), and the one end of gas-guide tube (9) far from catch tray (7)
Extend to the right along the bottom of support plate (2) and is fixedly connected with handle box (10)；
The bottom of handle box (10) is fixedly connected on the right side of box body (1) interior bottom, and fixed on the left of the inner cavity of handle box (10)
It is equipped with gas collection driving mechanism (11), handle box (10) is movably installed with driving member (12) in the middle part of interior rear wall bottom, and is driven
It is movably installed on part (12) defrosting mechanism (13), the upper half of defrosting mechanism (13) is fixedly mounted at the top of support plate (2)
Right side, and one end of drainage element (14), the other end of drainage element (14) are fixedly connected on the right side of defrosting mechanism (13) upper half
Through the right side of box body (1), the right side of water storage case (3) is connected to and in communication with by the water inlet of aqueduct and micro pump (15),
And the water outlet of micro pump (15) is connect with water delivery mechanism (16), the lower portion of water delivery mechanism (16) is interior in support plate (2),
And the upper half of water delivery mechanism (16) extends to the top of defrosting mechanism (13).
2. a kind of kit for hereditary tumor genetic test according to claim 1, it is characterised in that: the receipts
The inner cavity of catch basin (7) is up-narrow and down-wide shape, and side splicing of catch tray (7) inner wall close to water storage case (3) inner cavity has ventilative resistance
Moisture film (8).
3. a kind of kit for hereditary tumor genetic test according to claim 1, it is characterised in that: the life
Heat engine structure (6) includes reset button (601), placing frame (602), filter (603), storage capsule (604) and heats function for triggering
The stamp needle (605) of energy, reset button (601) is laterally interspersed to be connected in the left wall of box body (1), and the right side of reset button (601)
End is plugged in the left side of placing frame (602), and the left side of support plate (2) bottom is fixedly connected at the top of placing frame (602), is put
The left side of water storage case (3) inner top is run through in the bottom for setting frame (602), and four sides of filter (603) are respectively fixedly connected in placing frame
(602) bottom of four side of inner wall, reset button (601) interior button are fixedly connected with stamp needle close to one end of placing frame (602)
(605), and the inner left wall that needle (605) run through placing frame (602) far from the one end of reset button (601), the front of box body (1) are stabbed
It is hinged with folding piece (17), and opens and closes the front side that piece (17) run through fixed frame (601).
4. a kind of kit for hereditary tumor genetic test according to claim 1, it is characterised in that: the collection
Gas driving mechanism (11) includes fixed cylinder (111), the extension airbag (112) for saving bit by bit hot steam, is used for transmission hot steam
Connector (113), diaphragm seal (114), stabiliser bar (115), port (116), connecting tube (117), connecting cylinder (118) and appendix
(119), the left side of handle box (10) inner top is fixedly connected at the top of fixed cylinder (111), the top of extension airbag (112) is solid
Surely it is connected to the left side of handle box (10) inner top, and the side surface of extension airbag (112) and the inner wall of fixed cylinder (111) are close
Fitting, connector (113) are fixedly connected on the middle part of extension airbag (112) bottom and are connected to the inner cavity of extension airbag (112),
The quantity of diaphragm seal (114) is four, and the side surface of four diaphragm seals (114) contacts with each other and closes connector (113)
Inner cavity, stabiliser bar (115) are respectively welded at the left and right sides of connector (113), and port (116) is provided with fixed cylinder (111)
Bottom is simultaneously connected to its inner cavity, and connecting tube (117) is disposed longitudinally in port (116), and connecting cylinder (118) is fixed respectively in longitudinal
Be connected to the left and right sides of connecting tube (117), the front and rear sides of connecting cylinder (118) respectively with port (116) inner wall front and rear sides
Bottom be fixedly connected, the bottom end of two stabiliser bars (115) extends through two connecting cylinders (118) and through connecting cylinder (118)
Bottom end, the inner wall of connector (113) and the outer diameter of connecting tube (117) mutually agree with, and the central axes of connector (113) with
The central axes of connecting tube (117) are overlapped, and one end of appendix (119) is sleeved on the bottom end of connecting tube (117) by flange plate, and
The inner cavity of appendix (119) is connected to the inner cavity of connecting tube (117).
5. a kind of kit for hereditary tumor genetic test according to claim 1, it is characterised in that: the biography
Moving part (12) includes the inclined tab (122) for driving the turntable of defrosting mechanism (13) (121) and for bearing air-flow, turntable
(121) it is movably connected on the interior rear wall of handle box (10) by interting pin shaft in the center point, and turntable (121) is located at appendix
(119) right side of right end, inclined tab (122) is oblique and equidistantly around the front for being fixedly connected on turntable (121), is located at inclined tab
(122) right end of the inclined tab (122) of frontal left close to appendix (119).
6. a kind of kit for hereditary tumor genetic test according to claim 5, it is characterised in that: the solution
Freezing mechanism (13) includes for handling the hollow of solvent bottle (131), stop collar (132), for the annular sea of heated solvent bottle
Continuous (133), drive rod (134), semicircle part (135), brace (136), connecting rod (137) and slide guide item for promoting heating
(138), hollow (131) is fixedly connected on the rightmost side at the top of support plate (2), and the outer ring of stop collar (132) is fixedly connected on
On the inner wall of hollow (131), the bottom of annular sponge (133) is fixedly connected on the top of stop collar (132), drive rod
(134) quantity is two, and two drive rods (134) are in longitudinal left and right two being respectively interposed at the top of annular sponge (133)
In side, the bottom of support plate (2) is run through in the bottom end of two drive rods (134), offers in stop collar (132) and drive rod
(134) compatible through-hole, semicircle part (135) are threaded in the top of two drive rods (134), and two biographies in symmetry shape
The top of lever (134) is opposite to be bent, and the bottom end of two drive rods (134) is hinged with two braces (136) in symmetry shape, and
One end of two brace (136) phase seatback drive links (134) passes through the top that pin shaft is hinged on connecting rod (137), slide guide item
(138) rear side in connecting rod (137) is set and is fixedly connected on the interior rear wall of handle box (10), and slide guide item (138)
Front offers guide runner, and the pin shaft rear end that brace (136) and connecting rod (137) hingedly use is slidably connected in guide runner,
And the bottom end of connecting rod (137) is hinged on turntable (121) positive top.
7. a kind of kit for hereditary tumor genetic test according to claim 6, it is characterised in that: described defeated
Water dispenser structure (16) includes general pipeline (161), T shape pipe (162), bending tube (163), ring pipe (164) and the scupper for shunting
(165), the bottom end of general pipeline (161) and the water outlet of micro pump (15) are connected to and in communication with, and the top of general pipeline (161) is plugged on
In the bottom of support plate (2), T shape pipe (162) is laterally inlaid in support plate (2), and the left end of T shape pipe (162) and general pipeline
(161) the top welding on the right side of, the bottom end of bending tube (163) is welded on longer one section of the top of T shape pipe (162), bending tube
(163) top through support plate (2) top and extend to the tops of hollow (131), the left side of ring pipe (164) with it is curved
One section of shorter welding of broken pipe (163), scupper (165) is in equidistant bottom and and the ring for being provided with ring pipe (164) around shape
The inner cavity of shape pipe (164) is connected to, and general pipeline (161), T shape pipe (162), bending tube (163) are mutually interconnected with the inner cavity of ring pipe (164)
It is logical.
8. a kind of kit for hereditary tumor genetic test according to claim 1, it is characterised in that: the row
Water part (14) includes drainpipe (141) for being connected to box body (1) inner air and outer air and closes and open for drainpipe (141)
Swelling bag (142), drainpipe (141) are laterally interspersed in the right wall of box body (1), and the left end of drainpipe (141) is through hollow
Cylinder (131) on the right side of bottom and be connected to the inner cavity of hollow (131), swelling bag (142) is glued to the interior of drainpipe (141)
Wall.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910563869.XA CN110218629B (en) | 2019-06-26 | 2019-06-26 | Kit for genetic tumor gene detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910563869.XA CN110218629B (en) | 2019-06-26 | 2019-06-26 | Kit for genetic tumor gene detection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110218629A true CN110218629A (en) | 2019-09-10 |
| CN110218629B CN110218629B (en) | 2022-04-19 |
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ID=67814894
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910563869.XA Active CN110218629B (en) | 2019-06-26 | 2019-06-26 | Kit for genetic tumor gene detection |
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| Country | Link |
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| CN (1) | CN110218629B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113549526A (en) * | 2020-12-14 | 2021-10-26 | 吴玮 | DNA reaction kit for biological breeding |
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| Publication number | Publication date |
|---|---|
| CN110218629B (en) | 2022-04-19 |
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