CN110200820A - 一种可以反复液化再凝胶的凝胶体系及其制备方法 - Google Patents

一种可以反复液化再凝胶的凝胶体系及其制备方法 Download PDF

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CN110200820A
CN110200820A CN201910519286.7A CN201910519286A CN110200820A CN 110200820 A CN110200820 A CN 110200820A CN 201910519286 A CN201910519286 A CN 201910519286A CN 110200820 A CN110200820 A CN 110200820A
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parts
gel
liquefy
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卞前进
李亚维
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Jiangsu Gechuang Biotechnology Co Ltd
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Abstract

一种可以反复液化再凝胶的凝胶体系及其制备方法,涉及一种化装品和外用敷料技术领域,它包括由下述原料制备而成:聚丙烯酸铵,C13‑16异链烷烃,月桂醇聚醚‑25,黄原胶,结冷胶,1,2‑己二醇,馨鲜酮,甘油,葡聚糖,油脂,柠檬酸钠,氯化钙,水和适量活性成分。本发明的可以反复液化再凝胶的凝胶体系,可以很好的解决膏霜、乳液、精华液以及相关医用敷料的稳定性问题,解决了产品成分析出、油水分离、沉淀以及形成絮状物等问题。通过简单摇晃、搅拌、震荡或是通过挤压泵出等方式即将果冻状凝胶产品化为可以流动的液体,增加了产品的使用新颖性和清爽的使用感受。

Description

一种可以反复液化再凝胶的凝胶体系及其制备方法
技术领域
本发明涉及一种化装品和外用敷料技术领域,特别是一种可以反复液化再凝胶的凝胶体系及其制备方法。
背景技术
常见的化妆品和医用敷料剂型有水剂、乳霜剂、凝胶剂、粉剂、辅材吸附液体的冷敷贴等。普通的乳液稳定性会遇到悬浮力和稠度不足,容易出现油水分离的问题,稠度太高则使用感受粘腻或是无法倾倒出来或是泵压出来。再如,医用敷料通常会以高粘度形式出现,使用感粘腻,擦拭不便。
发明内容
本发明要解决的技术问题是针对现有技术的不足,提出了一种通过简单摇晃、搅拌、震荡或是通过挤压泵出等方式即将果冻状凝胶产品化为可以流动的液体的可以反复液化再凝胶的凝胶体系。本发明另一要解决的技术问题是提出了一种上述可以反复液化再凝胶的凝胶体系的一种制备方法。
本发明要解决的技术问题是通过以下技术方案来实现的,一种可以反复液化再凝胶的凝胶体系,其特点是,它包括由下述重量配比的原料制备而成的基料:
聚丙烯酸铵 0.01-3份,C13-16异链烷烃 0.1-6份,
月桂醇聚醚-25 0.1-5份,黄原胶 0.01-3份,
结冷胶 0.01-6份,1,2-己二醇 0.1-10份,
馨鲜酮 0.1-5份,甘油 1-10份,
葡聚糖 0.1-30份,油脂   0.1-10份,
柠檬酸钠 0.01-2份,氯化钙 0.01-5份,
水 60-90份。
本发明要解决的技术问题还可以通过以下技术方案来进一步实现,所述油脂为环五聚二甲基硅氧烷、聚二甲基硅氧烷、乙烯基聚二甲基硅氧烷交联聚合物、聚二甲基硅氧烷或苯基聚三甲基硅氧烷中的任意一种或任意几种的混合。
本发明要解决的技术问题还可以通过以下技术方案来进一步实现,所述油脂为环戊硅氧烷、环己硅氧烷、辛酸癸酸甘油酯、角鲨烷或矿油中的任意一种或任意几种的混合。
本发明要解决的技术问题还可以通过以下技术方案来进一步实现,在基料中添加有0.1-30份的活性成分。
本发明要解决的技术问题还可以通过以下技术方案来进一步实现,所述活性成分为虾青素、烟酰胺、维A醇、各类植物提取液或烟酰胺中一种或任意几种的组合。
一种上述可以反复液化再凝胶的凝胶体系的制备方法,其特点是:柠檬酸钠加水溶解后加热到78~90℃,加入聚丙烯酸铵、 C13-16异链烷烃和月桂醇聚醚-25,然后加入用甘油预分散的结冷胶、黄原胶,均质分散后,加入用水溶解的氯化钙,冷却后,加入其余组分混合均匀,静置成胶。
本发明与现有技术相比,本发明的可以反复液化再凝胶的凝胶体系,可以很好的解决膏霜、乳液、精华液以及相关医用敷料的稳定性问题,解决了产品成分析出、油水分离、沉淀以及形成絮状物等问题。此外,通过简单摇晃、搅拌、震荡或是通过挤压泵出等方式即将果冻状凝胶产品化为可以流动的液体,增加了产品的使用新颖性和清爽的使用感受。
具体实施方式
以下进一步描述本发明的具体技术方案,以便于本领域的技术人员进一步地理解本发明,而不构成对其权利的限制。
一种可以反复液化再凝胶的凝胶体系,它包括由下述重量配比的原料制备而成的基料:
聚丙烯酸铵 0.01-3份,C13-16异链烷烃 0.1-6份,
月桂醇聚醚-25 0.1-5份,黄原胶 0.01-3份,
结冷胶 0.01-6份,1,2-己二醇 0.1-10份,
馨鲜酮 0.1-5份,甘油 1-10份,
葡聚糖 0.1-30份,油脂   0.1-10份,
柠檬酸钠 0.01-2份,氯化钙 0.01-5份,
水 60-90份。
所述油脂为环五聚二甲基硅氧烷、聚二甲基硅氧烷、乙烯基聚二甲基硅氧烷交联聚合物、聚二甲基硅氧烷或苯基聚三甲基硅氧烷中的任意一种或任意几种的混合。
所述油脂还可以为环戊硅氧烷、环己硅氧烷、辛酸癸酸甘油酯、角鲨烷或矿油中的任意一种或任意几种的混合。
在基料中添加有0.1-30份的活性成分。所述活性成分为虾青素、烟酰胺、维A醇、各类植物提取液或烟酰胺中一种或任意几种的组合。
一种上述可以反复液化再凝胶的凝胶体系的制备方法,柠檬酸钠加水溶解后加热到78~90℃,加入聚丙烯酸铵、 C13-16异链烷烃和月桂醇聚醚-25,然后加入用甘油预分散的结冷胶、黄原胶,均质分散后,加入用水溶解的氯化钙,冷却后,加入其余组分混合均匀,静置成胶。
基料冷却静置成胶后可以根据需要,添加活性成分、香精、防腐剂等。
实施例1:
聚丙烯酸铵0.03份、 C13-16异链烷烃0.1份、月桂醇聚醚-25 0.2份、黄原胶0.03份、结冷胶0.05份、1,2-己二醇0.5份、馨鲜酮0.5份、甘油5份、葡聚糖30份、环五聚二甲基硅氧烷/聚二甲基硅氧烷/乙烯基聚二甲基硅氧烷交联聚合物/聚二甲基硅氧烷/苯基聚三甲基硅氧烷1份、柠檬酸钠0.05份、氯化钙0.05份、水62.49份
水、柠檬酸钠溶解加热80℃,加入聚丙烯酸铵、 C13-16异链烷烃、月桂醇聚醚-25,加入用甘油预分散的结冷胶、黄原胶,均质分散后,加入用水溶解的氯化钙,静置成胶。冷却后,加入其余组分。
实施例2:
聚丙烯酸铵0.5份、 C13-16异链烷烃0.1份、月桂醇聚醚-25 0.2份、黄原胶0.1份、结冷胶0.1份、甘油5份、柠檬酸钠0.05份、氯化钙0.05份、水93.9份。
水、柠檬酸钠溶解加热80℃,加入聚丙烯酸铵、 C13-16异链烷烃、月桂醇聚醚-25,加入用甘油预分散的结冷胶、黄原胶,均质分散后,加入用水溶解的氯化钙,静置成胶,冷却后,加入其余组分。
实施例3:
聚丙烯酸铵0.05份、 C13-16异链烷烃0.1份、月桂醇聚醚-25 0.3份、黄原胶0.3份、结冷胶0.05份、1,2-己二醇0.5份、馨鲜酮0.5份、甘油5份、透明质酸钠0.05份、环己硅氧烷2份、柠檬酸钠0.05份、氯化钙0.05份、虾青素0.1份、库拉索芦荟汁液5份、水85.95份
水、柠檬酸钠溶解加热80℃,加入聚丙烯酸铵、 C13-16异链烷烃、月桂醇聚醚-25、环己硅氧烷,加入用甘油预分散的结冷胶、黄原胶,均质分散后,加入用水溶解的氯化钙,静置成胶。冷却后,加入其余组分。
实施例4:
聚丙烯酸铵3份,C13-16异链烷烃6份,月桂醇聚醚-25 5份,黄原胶3份,结冷胶6份,1,2-己二醇 10份,馨鲜酮5份,甘油10份,葡聚糖30份,油脂10份,柠檬酸钠2份,氯化钙5份,水90份。
水、柠檬酸钠溶解加热80℃,加入聚丙烯酸铵、 C13-16异链烷烃、月桂醇聚醚-25、环己硅氧烷,加入用甘油预分散的结冷胶、黄原胶,均质分散后,加入用水溶解的氯化钙,静置成胶。冷却后,加入其余组分。

Claims (6)

1.一种可以反复液化再凝胶的凝胶体系,其特征在于,它包括由下述重量配比的原料制备而成的基料:
聚丙烯酸铵  0.01-3份,C13-16异链烷烃 0.1-6份,
月桂醇聚醚-25 0.1-5份,黄原胶     0.01-3份,
结冷胶    0.01-6份,1,2-己二醇   0.1-10份,
馨鲜酮     0.1-5份,甘油     1-10份,
葡聚糖     0.1-30份,油脂       0.1-10份,
柠檬酸钠    0.01-2份,氯化钙     0.01-5份,
水 60-90份。
2.根据权利要求1所述的可以反复液化再凝胶的凝胶体系,其特征在于:所述油脂为环五聚二甲基硅氧烷、聚二甲基硅氧烷、乙烯基聚二甲基硅氧烷交联聚合物、聚二甲基硅氧烷或苯基聚三甲基硅氧烷中的任意一种或任意几种的混合。
3.根据权利要求1所述的可以反复液化再凝胶的凝胶体系,其特征在于:所述油脂为环戊硅氧烷、环己硅氧烷、辛酸癸酸甘油酯、角鲨烷或矿油中的任意一种或任意几种的混合。
4.根据权利要求1所述的可以反复液化再凝胶的凝胶体系,其特征在于:在基料中添加有0.1-30份的活性成分。
5.根据权利要求4所述的可以反复液化再凝胶的凝胶体系,其特征在于:所述活性成分为虾青素、烟酰胺、维A醇、各类植物提取液或烟酰胺中一种或任意几种的组合。
6.一种上述可以反复液化再凝胶的凝胶体系的制备方法,其特征在于:柠檬酸钠加水溶解后加热到78~90℃,加入聚丙烯酸铵、 C13-16异链烷烃和月桂醇聚醚-25,然后加入用甘油预分散的结冷胶、黄原胶,均质分散后,加入用水溶解的氯化钙,冷却后,加入其余组分混合均匀,静置成胶。
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