CN110141663A - 通过控制血糖水平用于治疗糖尿病及相关病症的组合物、方法以及用途 - Google Patents

通过控制血糖水平用于治疗糖尿病及相关病症的组合物、方法以及用途 Download PDF

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Publication number
CN110141663A
CN110141663A CN201910123083.6A CN201910123083A CN110141663A CN 110141663 A CN110141663 A CN 110141663A CN 201910123083 A CN201910123083 A CN 201910123083A CN 110141663 A CN110141663 A CN 110141663A
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composition
glucose
diabetes
drug
compound
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Chinese (zh)
Inventor
丹尼尔·科恩
伊利亚·丘马克威
赛尔格·纳比洛克基恩
鲁道夫·哈吉
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Fa Nai Ces Co Ltd
Pharnext SA
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Fa Nai Ces Co Ltd
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
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    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
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  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201910123083.6A 2012-10-30 2013-10-30 通过控制血糖水平用于治疗糖尿病及相关病症的组合物、方法以及用途 Pending CN110141663A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261720156P 2012-10-30 2012-10-30
EP12306354.7A EP2727587A1 (en) 2012-10-30 2012-10-30 Compositions, methods and uses for the treatment of diabetes and related conditions by controlling blood glucose level
EP12306354.7 2012-10-30
US61/720,156 2012-10-30
CN201380069483.4A CN104981240B (zh) 2012-10-30 2013-10-30 通过控制血糖水平用于治疗糖尿病及相关病症的组合物、方法以及用途

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CN110141663A true CN110141663A (zh) 2019-08-20

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CN201380069483.4A Expired - Fee Related CN104981240B (zh) 2012-10-30 2013-10-30 通过控制血糖水平用于治疗糖尿病及相关病症的组合物、方法以及用途

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Country Status (17)

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US (2) US10092554B2 (OSRAM)
EP (3) EP2727587A1 (OSRAM)
JP (2) JP6387010B2 (OSRAM)
KR (1) KR20150081323A (OSRAM)
CN (2) CN110141663A (OSRAM)
AU (2) AU2013340826B2 (OSRAM)
BR (1) BR112015009702A2 (OSRAM)
CA (1) CA2888576C (OSRAM)
EA (1) EA031798B1 (OSRAM)
ES (2) ES2870028T3 (OSRAM)
HK (1) HK1214168A1 (OSRAM)
IL (1) IL238283A0 (OSRAM)
MX (1) MX2015005368A (OSRAM)
NZ (1) NZ707139A (OSRAM)
SG (2) SG10201801695XA (OSRAM)
WO (1) WO2014068007A1 (OSRAM)
ZA (1) ZA201503110B (OSRAM)

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CN112294827A (zh) * 2020-11-12 2021-02-02 四川大学华西医院 5-胆甾烯-3β-醇硫酸酯盐的新用途
CN115397414A (zh) * 2020-02-07 2022-11-25 株式会社纽若梵提 包含利美尼定的用于治疗脆性x染色体综合征的组合物
CN116940357A (zh) * 2021-03-08 2023-10-24 昂科克罗斯株式会社 包含托拉塞米以及色甘酸的用于预防或治疗代谢性疾病的组合物

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WO2014036528A2 (en) 2012-08-31 2014-03-06 Ixchel Pharma, Llc Agents useful for treating obesity, diabetes and related disorders
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
JP6540505B2 (ja) * 2013-03-29 2019-07-10 国立大学法人 熊本大学 2型糖尿病治療剤
ES2959444T3 (es) 2013-04-04 2024-02-26 Boehringer Ingelheim Vetmedica Gmbh Tratamiento de trastornos metabólicos en animales equinos
WO2015063140A1 (en) 2013-10-30 2015-05-07 Pharnext Compositions, methods and uses for the treatment of diabetes and related conditions by controlling blood glucose level
AU2014364999B2 (en) 2013-12-17 2019-12-12 Boehringer Ingelheim Vetmedica Gmbh Treatment of metabolic disorders in feline animals
EP3096765B1 (en) 2014-01-23 2018-12-05 Boehringer Ingelheim Vetmedica GmbH Treatment of metabolic disorders in canine animals
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
AU2015217796B2 (en) 2014-02-11 2020-04-30 Pharnext Combination of baclofen, acamprosate and medium chain triglycerides for the treatment of neurological disorders
KR20250096885A (ko) 2014-04-01 2025-06-27 베링거잉겔하임베트메디카게엠베하 말과 동물에서 대사 장애의 치료
US9839644B2 (en) 2014-09-09 2017-12-12 ARKAY Therapeutics, LLC Formulations and methods for treatment of metabolic syndrome
HUE068152T2 (hu) 2014-09-25 2024-12-28 Boehringer Ingelheim Vetmedica Gmbh SGLT2-gátlók és dopamin agonisták kombinációs kezelése anyagcserezavarok megelõzésére lófélékben
AU2015339576B2 (en) 2014-10-27 2020-02-06 Glytec, Llc Subcutaneous outpatient management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
CN104434952B (zh) * 2014-12-08 2017-10-24 成都恒瑞制药有限公司 一种治疗糖尿病的药物组合物及其制备方法
CN105055413A (zh) * 2015-07-23 2015-11-18 上海市第六人民医院 一种小檗碱和瑞格列奈的药物组合物
EP3337402B1 (en) 2015-08-20 2026-01-07 Glytec, LLC Diabetes management therapy advisor
EP3341024B1 (en) 2015-08-27 2024-10-09 Boehringer Ingelheim Vetmedica GmbH Liquid pharmaceutical compositions comprising sglt-2 inhibitors
US12359209B2 (en) 2018-04-17 2025-07-15 The Johns Hopkins Unversity Recombinant therapeutic interventions for cancer
US10918700B2 (en) * 2019-04-12 2021-02-16 Sdg, Inc. Lipid-based nanoparticles and use of same in optimized insulin dosing regimens
US20240009292A1 (en) * 2020-10-01 2024-01-11 The Johns Hopkins University Bcg based vaccine compositions and methods of use thereof
CN114786683B (zh) 2021-04-09 2024-01-12 北京大学 一种siRNA、药物组合物以及使用其治疗糖尿病的方法
WO2022225984A1 (en) * 2021-04-19 2022-10-27 Spruce Health Sciences Inc. Nutritional supplement for regulating blood sugar
KR20250038064A (ko) 2023-09-11 2025-03-19 김강숙 산양삼을 함유하는 김부각의 제조 방법 및 그 방법에 의해 제조된 김부각

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