CN110123676A - It is a kind of to utilize the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil - Google Patents

It is a kind of to utilize the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil Download PDF

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Publication number
CN110123676A
CN110123676A CN201910467386.XA CN201910467386A CN110123676A CN 110123676 A CN110123676 A CN 110123676A CN 201910467386 A CN201910467386 A CN 201910467386A CN 110123676 A CN110123676 A CN 110123676A
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raw material
medicinal
pressure
chinese medicine
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刘俚扬
郑超
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Beijing Yumeiyuan Science And Trade Co Ltd
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Beijing Yumeiyuan Science And Trade Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/37Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication

Abstract

The production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil is utilized the present invention relates to a kind of, steps are as follows: (1) raw material cleaning, drying, crushing, choosing medicinal raw material need to be pre-processed, medicinal material is cleaned, after drying, plant material is ground into powdery using pulverizer, it is spare to cross 30-40 mesh;(2) it pre-processes, powder raw material is fitted into container, extractant is added and impregnates, solid-liquid ratio 1:1-50;(3) filling and sealing;(4) extraction vessel equipped with plant material is put into super-pressure compression chamber, starting device, processing pressure 50-800MPa, dwell time 1-60min by super-pressure broken wall treatment, while circular treatment 2-3 times;(5) isothermal holding;(6) it filters.After process processed by the invention, the Chinese medicine medicine oil that there is antiallergic to releive effect is obtained.

Description

It is a kind of to utilize the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil
Technical field
The invention belongs to cosmetic fields, are related to Chinese medicine medicine oil production technology, especially a kind of to releive using with anti-inflammatory Effect medicinal material prepares the production technology of Chinese medicine medicine oil.
Background technique
Skin sensitivity is a kind of high response that skin goes out extraneous environment representation.The formation of skin sensitivity is by many factors It influences, mainly includes many factors collective effects such as endogenous factor and extrinsic factor.Endogenous factor mainly include gender, Age, skin type, disease etc..Extrinsic factor mainly includes environmental factor, chemical factor and life style etc..Skin allergy It is skin disease common at present, has seriously affected the physical and mental health of people.In recent years, the side effect of chemotherapy allergy It is increasingly prominent, therefore natural antiallergic constituents of releiving become research hotspot.
Chinese medicine has long applicating history in China, and safety and validity pass through the verifying of history already.It borrows Help scientific research methods, research finds that a variety of traditional medicines all have the working substance that antiallergic is releived, such as Asian puccoon, extract Also it is widely used in skin care item as antiallergic ingredient of releiving.Effective component in this kind of medicinal material is sufficiently extracted, is to guarantee to produce Product antiallergic is releived the basis of effect.
The research of superhigh pressure technique starts from 1914, which is at home and abroad mainly used in grocery trade, in order to It prevents the microbial contamination of food, extend the food storage time.Ultra high pressure extraction (ultrahigh-pressure Extraction, UHPE), also referred to as superelevation isostatic cool pressing is extracted, and refers to the hydrostatic pressure masterpiece for using 100-1000MPa at normal temperature For Extraction solvent and the mixed liquor for being extracted substance, and a period of time is kept under a predetermined, make to be extracted in substance External pressure reaches rapid release after balance, since inside and outside osmotic pressure increases suddenly, effective component is effectively passed through solid Liquid two-phase interface and be transferred in external Extraction medium, achieve the purpose that extract effective component in medicinal material.
The ingredient that there is antiallergic to releive effect in medicinal material is extracted using ultra high pressure extraction technology, is had the following characteristics that
1, extraction efficiency is high: since pressure is higher, solvent can be penetrated into very short time and is extracted in substance,
Effective component is set to reach dissolution equilibrium rapidly;
2, retain extract active constituent: although pressure rise, substance releases heat to the external world, due to high-pressure bottle and outside Boundary's environment has good heat exchange, can maintain to carry out at room temperature throughout the extraction process substantially, can farthest protect Active material in medicinal material has been stayed, the problems such as reducing because of thermally-induced effective component denaturation, loss and pharmacological activity is avoided;
3, it consumes energy low, highly-safe: ultra high pressure extraction process medium fluid deformation is smaller, the less energy intensive in fluid compression, The consumption and transmitting of noenergy in pressure maintaining and stress-relief process, the lesser compress of fluid will not generate in operation The volume change of increasing greatly reduces device because of device leakproofness bring risk.
Summary of the invention
It is an object of the invention to provide in place of overcome the deficiencies in the prior art, a kind of extraction time is short, and low energy consumption, effectively Constituents extraction rate is high, is prepared using traditional medicine a kind of using with anti-inflammatory effect medicinal material preparation of releiving with antioxidation The production technology of Chinese medicine medicine oil.
The present invention realizes that the technical solution of purpose is as follows:
It is a kind of to utilize the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil, after medicinal raw material crushes, warp Extractant impregnates, and is strengthened using super-pressure wall breaking technology and is extracted, and processing step is as follows:
(1) raw material cleaning, dry, crushing
It chooses medicinal raw material to be pre-processed, medicinal material is cleaned, after drying, is crushed into powder medicinal raw material using pulverizer It is spare to cross 30-40 mesh for shape;
(2) it pre-processes
Powder raw material is fitted into container, extractant is added and impregnates, is sufficiently stirred, impregnates 1-48h, obtains raw material sufficiently Infiltration, solid-liquid ratio 1:1-50, extractant be the mutatis mutandis catalogue of cosmetics in grease, caprylic/capric triglyceride, synthesis saualane, One of lauryl alcohol lactate, carbonic acid dioctyl ester, plant quasi-grease are a variety of;
(3) filling and sealing
It will be fitted into packaging bag by the raw material sufficiently impregnated, be sealed using vacuum sealer;
(4) super-pressure broken wall treatment
Extraction vessel equipped with medicinal raw material is put into super-pressure compression chamber, starting device, processing pressure 50- 800MPa, dwell time 1-60min, circular treatment 2-3 times;
(5) isothermal holding
After ultra high pressure treatment, extraction vessel is placed in 30-80 DEG C of isoperibol, keeps the temperature 24-72h, meanwhile, every 4- It is once ultrasonically treated within 6 hours, 10min per treatment, power 300w;
(7) it filters
It will treated obtains Chinese medicine medicine oil after feed liquid filtered using automatic deslagging filter.
Moreover, the raw material is honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus, solid-liquid ratio 1:1-9.
Moreover, raw material be honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus when super-pressure broken wall treatment pressure maintaining when Between be 15-30min.
Moreover, isothermal holding temperature when raw material is honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus is 40-50 ℃。
The advantages and positive effects of the present invention are:
The present invention provides a kind of production technology for utilizing and there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil, medicinal raw material After crushing, extracted dose of immersion is strengthened using super-pressure wall breaking technology and is extracted, and the production cycle shortens.And it is easy to operate, activity at Divide loss few, stable product quality is controllable;Using ultra high pressure extraction technology there are many advantage, including extraction time is short, low energy consumption, Effective component inactivation, loss etc. caused by effective component extraction rate height and avoidable fuel factor.
Specific embodiment
The method of the present invention is described below by specific embodiment.Unless stated otherwise, technology used in the present invention Means are method known in those skilled in the art.In addition, embodiment is interpreted as illustrative, rather than this hair is limited Bright range, the spirit and scope of the invention are limited only by the claims that follow.To those skilled in the art, it is not carrying on the back Under the premise of from spirit and scope of the present invention, in these embodiments material component and dosage carry out various changes or change It is dynamic to also belong to protection scope of the present invention.
The present invention provide a kind of preparation of medicinal material have antiallergic releive effect Chinese medicine medicine oil production technology, specifically include with Lower step:
1, raw material cleaning, drying, crushing
Medicinal material honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus is chosen to be pre-processed.Medicinal material is cleaned, is dried Afterwards, plant material is ground into powdery using pulverizer, it is spare crosses 40 meshes.
2, it pre-processes
Powder raw material is fitted into container, extractant is added, and (extractant should be cosmetics and use permits in raw material catalogue The various greases that use, such as caprylic/capric triglyceride, lauryl alcohol lactate) it impregnates, solid-liquid ratio 1:1-1:50, more preferably 1:1-1:10, more preferable 1:1-1:4, and be sufficiently stirred, 1-48h is impregnated, (preferably 6-8h) infiltrates raw material sufficiently.
3, filling and sealing
It will be fitted into packaging bag by the raw material sufficiently impregnated, be sealed using vacuum sealer;
4, super-pressure broken wall treatment
Container equipped with medicinal raw material is put into super-pressure compression chamber, starting device, processing pressure 50-800MPa, is protected The pressure time is 1-60min, preferably 15-30min, while circular treatment 2-3 times.
5, isothermal holding
After ultra high pressure treatment, extraction vessel is placed higher than in the isoperibol of room temperature (30-80 DEG C), preferably 40-50 DEG C, To avoid the destruction of the excessively high effective component to leaching of temperature, and the oxidation of extractant is avoided, keeps the temperature 24-72h.Meanwhile It was once ultrasonically treated every 4-6 hours (per treatment 10min, power 300w).Crude drug cell is broken by super-pressure Wall effect further leaches the effective component in medicinal material using ultrasonic wave added method.The medicine handled through this processing mode Oil shortens the production cycle of medicine oil.
6, it filters
Chinese medicine medicine oil will be obtained after the filtering of treated feed liquid.
Here is that the embodiment of Chinese medicine medicine oil is prepared according to different ratio extracting solution and various extracting conditions, specific interior Hold as follows:
Embodiment 1:
The preparation of lonicera oil: being extractant, material ratio 1:1, ultra-high pressure condition using caprylic/capric triglyceride 100MPa, dwell time 20min, 40 DEG C of isothermal holding 48h are during which primary every 6h ultrasonic treatment, 10min per treatment, mistake Filter obtains product.
Embodiment 2:
The preparation of lonicera oil: being extractant using lauryl alcohol lactate, and material ratio 1:1, ultra-high pressure condition 200MPa are protected Time 20min, 40 DEG C of isothermal holding 48h are pressed, during which primary every 6h ultrasonic treatment, product is obtained by filtration in each 10min.
Embodiment 3:
The preparation of its sesame oil: being extractant using caprylic/capric triglyceride, lauryl alcohol lactate compound lard (1:4), During which material ratio 1:1, ultra-high pressure condition 400MPa, dwell time 20min, 40 DEG C of isothermal holding 48h are ultrasonically treated one every 6h Secondary, product is obtained by filtration in 10min per treatment.
Embodiment 4:
The preparation of dragon's blood oil: being extractant using caprylic/capric triglyceride, lauryl alcohol lactate compound lard (1:2), Material ratio 1:1, ultra-high pressure condition 400MPa, dwell time 20min, 40 DEG C of placement 48h are during which primary every 6h ultrasonic treatment, 10min per treatment, is obtained by filtration product.
Embodiment 5:
The preparation of dragon's blood oil: being extractant, object using caprylic/capric triglyceride, carbonic acid dibutyl ester compound lard (1:3) Material is than 1:1, ultra-high pressure condition 400MPa, dwell time 20min, and 40 DEG C of placement 48h are during which primary every 6h ultrasonic treatment, often Secondary processing 10min, is obtained by filtration product.
Embodiment 6:
The preparation of Groomwell root oil: being extractant using caprylic/capric triglyceride, lauryl alcohol lactate compound lard (1:1), Material ratio 1:1, ultra-high pressure condition 400MPa, dwell time 20min, 40 DEG C of placement 48h are during which primary every 6h ultrasonic treatment, 10min per treatment, is obtained by filtration product.
Embodiment 7:
The preparation of Groomwell root oil: being to extract using caprylic/capric triglyceride, lauryl alcohol lactate compound lard (1:0.5) During which agent, material ratio 1:1, ultra-high pressure condition 400MPa, dwell time 20min, 40 DEG C of placement 48h are ultrasonically treated one every 6h Secondary, product is obtained by filtration in 10min per treatment.
Embodiment 8:
The preparation of bulbus fritillariae cirrhosae oil: being to extract using caprylic/capric triglyceride, Parleam compound lard (1:4) During which agent, material ratio 1:1, ultra-high pressure condition 500MPa, dwell time 20min, 40 DEG C of placement 48h are ultrasonically treated one every 6h Secondary, product is obtained by filtration in each 10min.
Embodiment 9:
The preparation of bulbus fritillariae cirrhosae oil: being extractant, material ratio 1:1, ultra-high pressure condition using carbonic acid dibutyl ester compound lard 600MPa, dwell time 20min, 40 DEG C of placement 48h, during which primary every 6h ultrasonic treatment, production is obtained by filtration in each 10min Product.
Embodiment 10:
The preparation of Moschus oil: being extractant, material ratio 1:1, ultra-high pressure condition using carbonic acid dibutyl ester compound lard 600MPa, dwell time 20min, 40 DEG C of placement 48h, during which primary every 6h ultrasonic treatment, production is obtained by filtration in each 10min Product.
Using ultra high pressure extraction technology, so that the effective component in medicinal material is easier to be extracted agent and is taken out of, pass through heat preservation, ultrasound etc. Householder method can be greatly improved in the short time to the extraction efficiency in medicinal material with antioxidation ingredient.
The present invention uses caprylic/capric triglyceride, synthesis saualane, lauryl alcohol lactate, carbonic acid dioctyl ester, plant Grease etc. is used as Extraction medium, avoids when extracting the substance using conventional organic solvents, the dissolvent residual that may cause is asked Topic, improves safety of the products application in daily use chemicals industry, while also can guarantee the leaching efficiency of the effective component in medicinal material.

Claims (3)

1. it is a kind of using the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil, after medicinal raw material crushes, through mentioning It takes agent to impregnate, is strengthened using super-pressure wall breaking technology and extracted, it is characterised in that: processing step is as follows:
(1) raw material cleaning, dry, crushing
It chooses medicinal raw material to be pre-processed, medicinal material is cleaned, after drying, medicinal raw material is ground into powdery using pulverizer, It is spare to cross 30-40 mesh;
(2) it pre-processes
Powder raw material is fitted into container, extractant is added and impregnates, is sufficiently stirred, impregnates 1-48h, soaks raw material sufficiently Profit, solid-liquid ratio 1:1-50, extractant are grease in the mutatis mutandis catalogue of cosmetics, caprylic/capric triglyceride, synthesis saualane, the moon One of cinnamic alcohol lactate, carbonic acid dioctyl ester, plant quasi-grease are a variety of;
(3) filling and sealing
It will be fitted into packaging bag by the raw material sufficiently impregnated, be sealed using vacuum sealer;
(4) super-pressure broken wall treatment
Extraction vessel equipped with medicinal raw material is put into super-pressure compression chamber, starting device, processing pressure 50-800MPa, is protected The pressure time is 1-60min, circular treatment 2-3 times;
(5) isothermal holding
After ultra high pressure treatment, extraction vessel is placed in 30-80 DEG C of isoperibol, keeps the temperature 24-72h, meanwhile, it is small every 4-6 Shi Jinhang is once ultrasonically treated, 10min per treatment, power 300w;
(6) it filters
It will treated obtains Chinese medicine medicine oil after feed liquid filtered using automatic deslagging filter;
The raw material is honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus, solid-liquid ratio 1:1-9.
2. the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil for a kind of utilization according to claim 1, It is characterized by: super-pressure broken wall treatment dwell time when raw material is honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus For 15-30min.
3. the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil for a kind of utilization according to claim 1, It is characterized by: isothermal holding temperature when raw material is honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus is 40-50 DEG C.
CN201910467386.XA 2019-05-31 2019-05-31 It is a kind of to utilize the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil Withdrawn CN110123676A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114344216A (en) * 2022-01-19 2022-04-15 浙江宜格企业管理集团有限公司 Preparation method and application of alkanna tinctoria root extract with stable color
CN116474414A (en) * 2023-06-21 2023-07-25 广东汇群中药饮片股份有限公司 Ultrasonic-assisted leaching device and application thereof in extraction of total flavonoids of honeysuckle

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CN103257187A (en) * 2012-10-10 2013-08-21 苏州大学 Chlorogenic acid and galuteolin in honeysuckle flower superhigh pressure extraction method and HPLC quantitative analysis method
CN104841156A (en) * 2015-05-09 2015-08-19 东北师范大学 Method for extracting effective components in plants by using ultrahigh pressure equipment
CN108096073A (en) * 2017-12-27 2018-06-01 北京同德展科贸有限公司 Production technology and the application of Chinese medicine medicine oil are prepared using Umbellales Umbelliferae medicinal material

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Publication number Priority date Publication date Assignee Title
CN103257187A (en) * 2012-10-10 2013-08-21 苏州大学 Chlorogenic acid and galuteolin in honeysuckle flower superhigh pressure extraction method and HPLC quantitative analysis method
CN104841156A (en) * 2015-05-09 2015-08-19 东北师范大学 Method for extracting effective components in plants by using ultrahigh pressure equipment
CN108096073A (en) * 2017-12-27 2018-06-01 北京同德展科贸有限公司 Production technology and the application of Chinese medicine medicine oil are prepared using Umbellales Umbelliferae medicinal material

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114344216A (en) * 2022-01-19 2022-04-15 浙江宜格企业管理集团有限公司 Preparation method and application of alkanna tinctoria root extract with stable color
CN114344216B (en) * 2022-01-19 2024-02-13 浙江宜格企业管理集团有限公司 Preparation method and application of lithospermum root extract with stable color
CN116474414A (en) * 2023-06-21 2023-07-25 广东汇群中药饮片股份有限公司 Ultrasonic-assisted leaching device and application thereof in extraction of total flavonoids of honeysuckle
CN116474414B (en) * 2023-06-21 2023-09-01 广东汇群中药饮片股份有限公司 Ultrasonic-assisted leaching device and application thereof in extraction of total flavonoids of honeysuckle

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