CN110123676A - It is a kind of to utilize the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil - Google Patents
It is a kind of to utilize the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil Download PDFInfo
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- CN110123676A CN110123676A CN201910467386.XA CN201910467386A CN110123676A CN 110123676 A CN110123676 A CN 110123676A CN 201910467386 A CN201910467386 A CN 201910467386A CN 110123676 A CN110123676 A CN 110123676A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/925—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/37—Extraction at elevated pressure or temperature, e.g. pressurized solvent extraction [PSE], supercritical carbon dioxide extraction or subcritical water extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
Abstract
The production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil is utilized the present invention relates to a kind of, steps are as follows: (1) raw material cleaning, drying, crushing, choosing medicinal raw material need to be pre-processed, medicinal material is cleaned, after drying, plant material is ground into powdery using pulverizer, it is spare to cross 30-40 mesh;(2) it pre-processes, powder raw material is fitted into container, extractant is added and impregnates, solid-liquid ratio 1:1-50;(3) filling and sealing;(4) extraction vessel equipped with plant material is put into super-pressure compression chamber, starting device, processing pressure 50-800MPa, dwell time 1-60min by super-pressure broken wall treatment, while circular treatment 2-3 times;(5) isothermal holding;(6) it filters.After process processed by the invention, the Chinese medicine medicine oil that there is antiallergic to releive effect is obtained.
Description
Technical field
The invention belongs to cosmetic fields, are related to Chinese medicine medicine oil production technology, especially a kind of to releive using with anti-inflammatory
Effect medicinal material prepares the production technology of Chinese medicine medicine oil.
Background technique
Skin sensitivity is a kind of high response that skin goes out extraneous environment representation.The formation of skin sensitivity is by many factors
It influences, mainly includes many factors collective effects such as endogenous factor and extrinsic factor.Endogenous factor mainly include gender,
Age, skin type, disease etc..Extrinsic factor mainly includes environmental factor, chemical factor and life style etc..Skin allergy
It is skin disease common at present, has seriously affected the physical and mental health of people.In recent years, the side effect of chemotherapy allergy
It is increasingly prominent, therefore natural antiallergic constituents of releiving become research hotspot.
Chinese medicine has long applicating history in China, and safety and validity pass through the verifying of history already.It borrows
Help scientific research methods, research finds that a variety of traditional medicines all have the working substance that antiallergic is releived, such as Asian puccoon, extract
Also it is widely used in skin care item as antiallergic ingredient of releiving.Effective component in this kind of medicinal material is sufficiently extracted, is to guarantee to produce
Product antiallergic is releived the basis of effect.
The research of superhigh pressure technique starts from 1914, which is at home and abroad mainly used in grocery trade, in order to
It prevents the microbial contamination of food, extend the food storage time.Ultra high pressure extraction (ultrahigh-pressure
Extraction, UHPE), also referred to as superelevation isostatic cool pressing is extracted, and refers to the hydrostatic pressure masterpiece for using 100-1000MPa at normal temperature
For Extraction solvent and the mixed liquor for being extracted substance, and a period of time is kept under a predetermined, make to be extracted in substance
External pressure reaches rapid release after balance, since inside and outside osmotic pressure increases suddenly, effective component is effectively passed through solid
Liquid two-phase interface and be transferred in external Extraction medium, achieve the purpose that extract effective component in medicinal material.
The ingredient that there is antiallergic to releive effect in medicinal material is extracted using ultra high pressure extraction technology, is had the following characteristics that
1, extraction efficiency is high: since pressure is higher, solvent can be penetrated into very short time and is extracted in substance,
Effective component is set to reach dissolution equilibrium rapidly;
2, retain extract active constituent: although pressure rise, substance releases heat to the external world, due to high-pressure bottle and outside
Boundary's environment has good heat exchange, can maintain to carry out at room temperature throughout the extraction process substantially, can farthest protect
Active material in medicinal material has been stayed, the problems such as reducing because of thermally-induced effective component denaturation, loss and pharmacological activity is avoided;
3, it consumes energy low, highly-safe: ultra high pressure extraction process medium fluid deformation is smaller, the less energy intensive in fluid compression,
The consumption and transmitting of noenergy in pressure maintaining and stress-relief process, the lesser compress of fluid will not generate in operation
The volume change of increasing greatly reduces device because of device leakproofness bring risk.
Summary of the invention
It is an object of the invention to provide in place of overcome the deficiencies in the prior art, a kind of extraction time is short, and low energy consumption, effectively
Constituents extraction rate is high, is prepared using traditional medicine a kind of using with anti-inflammatory effect medicinal material preparation of releiving with antioxidation
The production technology of Chinese medicine medicine oil.
The present invention realizes that the technical solution of purpose is as follows:
It is a kind of to utilize the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil, after medicinal raw material crushes, warp
Extractant impregnates, and is strengthened using super-pressure wall breaking technology and is extracted, and processing step is as follows:
(1) raw material cleaning, dry, crushing
It chooses medicinal raw material to be pre-processed, medicinal material is cleaned, after drying, is crushed into powder medicinal raw material using pulverizer
It is spare to cross 30-40 mesh for shape;
(2) it pre-processes
Powder raw material is fitted into container, extractant is added and impregnates, is sufficiently stirred, impregnates 1-48h, obtains raw material sufficiently
Infiltration, solid-liquid ratio 1:1-50, extractant be the mutatis mutandis catalogue of cosmetics in grease, caprylic/capric triglyceride, synthesis saualane,
One of lauryl alcohol lactate, carbonic acid dioctyl ester, plant quasi-grease are a variety of;
(3) filling and sealing
It will be fitted into packaging bag by the raw material sufficiently impregnated, be sealed using vacuum sealer;
(4) super-pressure broken wall treatment
Extraction vessel equipped with medicinal raw material is put into super-pressure compression chamber, starting device, processing pressure 50-
800MPa, dwell time 1-60min, circular treatment 2-3 times;
(5) isothermal holding
After ultra high pressure treatment, extraction vessel is placed in 30-80 DEG C of isoperibol, keeps the temperature 24-72h, meanwhile, every 4-
It is once ultrasonically treated within 6 hours, 10min per treatment, power 300w;
(7) it filters
It will treated obtains Chinese medicine medicine oil after feed liquid filtered using automatic deslagging filter.
Moreover, the raw material is honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus, solid-liquid ratio 1:1-9.
Moreover, raw material be honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus when super-pressure broken wall treatment pressure maintaining when
Between be 15-30min.
Moreover, isothermal holding temperature when raw material is honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus is 40-50
℃。
The advantages and positive effects of the present invention are:
The present invention provides a kind of production technology for utilizing and there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil, medicinal raw material
After crushing, extracted dose of immersion is strengthened using super-pressure wall breaking technology and is extracted, and the production cycle shortens.And it is easy to operate, activity at
Divide loss few, stable product quality is controllable;Using ultra high pressure extraction technology there are many advantage, including extraction time is short, low energy consumption,
Effective component inactivation, loss etc. caused by effective component extraction rate height and avoidable fuel factor.
Specific embodiment
The method of the present invention is described below by specific embodiment.Unless stated otherwise, technology used in the present invention
Means are method known in those skilled in the art.In addition, embodiment is interpreted as illustrative, rather than this hair is limited
Bright range, the spirit and scope of the invention are limited only by the claims that follow.To those skilled in the art, it is not carrying on the back
Under the premise of from spirit and scope of the present invention, in these embodiments material component and dosage carry out various changes or change
It is dynamic to also belong to protection scope of the present invention.
The present invention provide a kind of preparation of medicinal material have antiallergic releive effect Chinese medicine medicine oil production technology, specifically include with
Lower step:
1, raw material cleaning, drying, crushing
Medicinal material honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus is chosen to be pre-processed.Medicinal material is cleaned, is dried
Afterwards, plant material is ground into powdery using pulverizer, it is spare crosses 40 meshes.
2, it pre-processes
Powder raw material is fitted into container, extractant is added, and (extractant should be cosmetics and use permits in raw material catalogue
The various greases that use, such as caprylic/capric triglyceride, lauryl alcohol lactate) it impregnates, solid-liquid ratio 1:1-1:50, more preferably
1:1-1:10, more preferable 1:1-1:4, and be sufficiently stirred, 1-48h is impregnated, (preferably 6-8h) infiltrates raw material sufficiently.
3, filling and sealing
It will be fitted into packaging bag by the raw material sufficiently impregnated, be sealed using vacuum sealer;
4, super-pressure broken wall treatment
Container equipped with medicinal raw material is put into super-pressure compression chamber, starting device, processing pressure 50-800MPa, is protected
The pressure time is 1-60min, preferably 15-30min, while circular treatment 2-3 times.
5, isothermal holding
After ultra high pressure treatment, extraction vessel is placed higher than in the isoperibol of room temperature (30-80 DEG C), preferably 40-50 DEG C,
To avoid the destruction of the excessively high effective component to leaching of temperature, and the oxidation of extractant is avoided, keeps the temperature 24-72h.Meanwhile
It was once ultrasonically treated every 4-6 hours (per treatment 10min, power 300w).Crude drug cell is broken by super-pressure
Wall effect further leaches the effective component in medicinal material using ultrasonic wave added method.The medicine handled through this processing mode
Oil shortens the production cycle of medicine oil.
6, it filters
Chinese medicine medicine oil will be obtained after the filtering of treated feed liquid.
Here is that the embodiment of Chinese medicine medicine oil is prepared according to different ratio extracting solution and various extracting conditions, specific interior
Hold as follows:
Embodiment 1:
The preparation of lonicera oil: being extractant, material ratio 1:1, ultra-high pressure condition using caprylic/capric triglyceride
100MPa, dwell time 20min, 40 DEG C of isothermal holding 48h are during which primary every 6h ultrasonic treatment, 10min per treatment, mistake
Filter obtains product.
Embodiment 2:
The preparation of lonicera oil: being extractant using lauryl alcohol lactate, and material ratio 1:1, ultra-high pressure condition 200MPa are protected
Time 20min, 40 DEG C of isothermal holding 48h are pressed, during which primary every 6h ultrasonic treatment, product is obtained by filtration in each 10min.
Embodiment 3:
The preparation of its sesame oil: being extractant using caprylic/capric triglyceride, lauryl alcohol lactate compound lard (1:4),
During which material ratio 1:1, ultra-high pressure condition 400MPa, dwell time 20min, 40 DEG C of isothermal holding 48h are ultrasonically treated one every 6h
Secondary, product is obtained by filtration in 10min per treatment.
Embodiment 4:
The preparation of dragon's blood oil: being extractant using caprylic/capric triglyceride, lauryl alcohol lactate compound lard (1:2),
Material ratio 1:1, ultra-high pressure condition 400MPa, dwell time 20min, 40 DEG C of placement 48h are during which primary every 6h ultrasonic treatment,
10min per treatment, is obtained by filtration product.
Embodiment 5:
The preparation of dragon's blood oil: being extractant, object using caprylic/capric triglyceride, carbonic acid dibutyl ester compound lard (1:3)
Material is than 1:1, ultra-high pressure condition 400MPa, dwell time 20min, and 40 DEG C of placement 48h are during which primary every 6h ultrasonic treatment, often
Secondary processing 10min, is obtained by filtration product.
Embodiment 6:
The preparation of Groomwell root oil: being extractant using caprylic/capric triglyceride, lauryl alcohol lactate compound lard (1:1),
Material ratio 1:1, ultra-high pressure condition 400MPa, dwell time 20min, 40 DEG C of placement 48h are during which primary every 6h ultrasonic treatment,
10min per treatment, is obtained by filtration product.
Embodiment 7:
The preparation of Groomwell root oil: being to extract using caprylic/capric triglyceride, lauryl alcohol lactate compound lard (1:0.5)
During which agent, material ratio 1:1, ultra-high pressure condition 400MPa, dwell time 20min, 40 DEG C of placement 48h are ultrasonically treated one every 6h
Secondary, product is obtained by filtration in 10min per treatment.
Embodiment 8:
The preparation of bulbus fritillariae cirrhosae oil: being to extract using caprylic/capric triglyceride, Parleam compound lard (1:4)
During which agent, material ratio 1:1, ultra-high pressure condition 500MPa, dwell time 20min, 40 DEG C of placement 48h are ultrasonically treated one every 6h
Secondary, product is obtained by filtration in each 10min.
Embodiment 9:
The preparation of bulbus fritillariae cirrhosae oil: being extractant, material ratio 1:1, ultra-high pressure condition using carbonic acid dibutyl ester compound lard
600MPa, dwell time 20min, 40 DEG C of placement 48h, during which primary every 6h ultrasonic treatment, production is obtained by filtration in each 10min
Product.
Embodiment 10:
The preparation of Moschus oil: being extractant, material ratio 1:1, ultra-high pressure condition using carbonic acid dibutyl ester compound lard
600MPa, dwell time 20min, 40 DEG C of placement 48h, during which primary every 6h ultrasonic treatment, production is obtained by filtration in each 10min
Product.
Using ultra high pressure extraction technology, so that the effective component in medicinal material is easier to be extracted agent and is taken out of, pass through heat preservation, ultrasound etc.
Householder method can be greatly improved in the short time to the extraction efficiency in medicinal material with antioxidation ingredient.
The present invention uses caprylic/capric triglyceride, synthesis saualane, lauryl alcohol lactate, carbonic acid dioctyl ester, plant
Grease etc. is used as Extraction medium, avoids when extracting the substance using conventional organic solvents, the dissolvent residual that may cause is asked
Topic, improves safety of the products application in daily use chemicals industry, while also can guarantee the leaching efficiency of the effective component in medicinal material.
Claims (3)
1. it is a kind of using the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil, after medicinal raw material crushes, through mentioning
It takes agent to impregnate, is strengthened using super-pressure wall breaking technology and extracted, it is characterised in that: processing step is as follows:
(1) raw material cleaning, dry, crushing
It chooses medicinal raw material to be pre-processed, medicinal material is cleaned, after drying, medicinal raw material is ground into powdery using pulverizer,
It is spare to cross 30-40 mesh;
(2) it pre-processes
Powder raw material is fitted into container, extractant is added and impregnates, is sufficiently stirred, impregnates 1-48h, soaks raw material sufficiently
Profit, solid-liquid ratio 1:1-50, extractant are grease in the mutatis mutandis catalogue of cosmetics, caprylic/capric triglyceride, synthesis saualane, the moon
One of cinnamic alcohol lactate, carbonic acid dioctyl ester, plant quasi-grease are a variety of;
(3) filling and sealing
It will be fitted into packaging bag by the raw material sufficiently impregnated, be sealed using vacuum sealer;
(4) super-pressure broken wall treatment
Extraction vessel equipped with medicinal raw material is put into super-pressure compression chamber, starting device, processing pressure 50-800MPa, is protected
The pressure time is 1-60min, circular treatment 2-3 times;
(5) isothermal holding
After ultra high pressure treatment, extraction vessel is placed in 30-80 DEG C of isoperibol, keeps the temperature 24-72h, meanwhile, it is small every 4-6
Shi Jinhang is once ultrasonically treated, 10min per treatment, power 300w;
(6) it filters
It will treated obtains Chinese medicine medicine oil after feed liquid filtered using automatic deslagging filter;
The raw material is honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus, solid-liquid ratio 1:1-9.
2. the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil for a kind of utilization according to claim 1,
It is characterized by: super-pressure broken wall treatment dwell time when raw material is honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus
For 15-30min.
3. the production technology that there is anti-inflammatory effect medicinal material of releiving to prepare Chinese medicine medicine oil for a kind of utilization according to claim 1,
It is characterized by: isothermal holding temperature when raw material is honeysuckle, dragon's blood, Asian puccoon, bulbus fritillariae cirrhosae, Rhizoma Gastrodiae, Moschus is 40-50 DEG C.
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Cited By (2)
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CN114344216A (en) * | 2022-01-19 | 2022-04-15 | 浙江宜格企业管理集团有限公司 | Preparation method and application of alkanna tinctoria root extract with stable color |
CN116474414A (en) * | 2023-06-21 | 2023-07-25 | 广东汇群中药饮片股份有限公司 | Ultrasonic-assisted leaching device and application thereof in extraction of total flavonoids of honeysuckle |
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CN103257187A (en) * | 2012-10-10 | 2013-08-21 | 苏州大学 | Chlorogenic acid and galuteolin in honeysuckle flower superhigh pressure extraction method and HPLC quantitative analysis method |
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CN114344216A (en) * | 2022-01-19 | 2022-04-15 | 浙江宜格企业管理集团有限公司 | Preparation method and application of alkanna tinctoria root extract with stable color |
CN114344216B (en) * | 2022-01-19 | 2024-02-13 | 浙江宜格企业管理集团有限公司 | Preparation method and application of lithospermum root extract with stable color |
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