CN110101789A - The Chinese materia medica preparation for treating insomnia - Google Patents
The Chinese materia medica preparation for treating insomnia Download PDFInfo
- Publication number
- CN110101789A CN110101789A CN201910476293.3A CN201910476293A CN110101789A CN 110101789 A CN110101789 A CN 110101789A CN 201910476293 A CN201910476293 A CN 201910476293A CN 110101789 A CN110101789 A CN 110101789A
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- China
- Prior art keywords
- parts
- ginseng
- lily
- radix angelicae
- angelicae sinensis
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8967—Lilium, e.g. tiger lily or Easter lily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
Abstract
The invention belongs to field of traditional Chinese medicine preparations, in particular to a kind of Chinese materia medica preparation for treating insomnia, is made of the Chinese medicine material of following parts by weight: 3-5 parts of semen ziziphi spinosae, 3-5 parts of lily, 3-5 parts of Radix Angelicae Sinensis, 1-2 parts of ginseng, 1-2 parts of Schisandra chinensis, has supplementing qi and nourishing yin, it is nourishing liver and kidney, the effect of antitoxic heart-soothing and sedative.The present invention be on the basis of traditional tcm treatment according to syndrome differentiation combine clinical practice develop, have the characteristics that curative for effect, safe ready, it is quick, have no toxic side effect.
Description
Technical field
A kind of Chinese materia medica preparation for treating insomnia of the present invention, has the medicine for the treatment of sleep using natural plant crude drugs as main component
Object and preparation method.
Background technique
Sleep is a kind of basic physiological behavior, is to ensure physically and mentally healthy essential condition.With social progress, modernization
The quickening of process, economy are grown rapidly, and the increase of social diversity and competitive pressure, sleeping problems have become one and increasingly dash forward
Out the problem of.Proper well sleep is kept, adjustable physiological function maintains the balance of nervous system, is important in life
A ring.Dyssomnia or deficiency, will lead to feel dizzy, general weakness, immunity degradation, and aggravate other diseases or induction
The breaking-out of original disease.It sleeps closely related with the health of the mankind, work, living and studying.
Sleep declined less with qi and blood it is relatively conventional, the internal organs being related to intentionally, spleen, liver, gallbladder, kidney, the interpretation of the cause, onset and process of an illness is mainly that qi and blood declines
It is few, cause body visceral dysfunction, yin-yang to be become estranged, so that having no peace of mind or mind dystrophy.Viscera function normal operation is coordinated,
Yinyang normal operation is the important leverage of ortho.This product is with traditional Chinese medicine semen ziziphi spinosae, ginseng, lily, Radix Angelicae Sinensis, five
Taste is raw material, and supplementing qi and nourishing yin is nourishing liver and kidney, and antitoxic heart-soothing and sedative rationally adjusts viscera function, to reach the mesh for improving sleep
's.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of Chinese materia medica preparations for treating insomnia, have quick, healing
Rate height, safe ready, the characteristics of having no toxic side effect.
A kind of Chinese materia medica preparation for treating insomnia of the present invention, it is characterised in that be made of the raw material of following parts by weight: wild jujube
3-5 parts of benevolence, 3-5 parts of lily, 3-5 parts of Radix Angelicae Sinensis, 1-2 parts of ginseng, 1-2 parts of Schisandra chinensis.
Preparation method: semen ziziphi spinosae, ginseng, lily, Radix Angelicae Sinensis, Schisandra chinensis distinguish net system, use after the assay was approved for preparation；It takes
Appropriate ginseng, crushed after being dried, sieving sterilize spare；Semen ziziphi spinosae, Schisandra chinensis, surplus ginseng are taken, alcohol reflux is added and extracts 2
It is secondary；Filtration, merging filtrate (the another device of the dregs of a decoction saves), filtrate recycling ethanol is concentrated into clear cream, spare；Take Radix Angelicae Sinensis, lily with it is above-mentioned
The alcohol extracting dregs of a decoction add water to cook 2 times, and filtration, merging filtrate (dregs of a decoction discard), filtrate decompression is concentrated into the clear cream of relative density, standby
With；Merge above two clear cream, be dried under reduced pressure, crush, sieving, gained cream powder and ginseng fine powder mix, and required medicament is made.
The Chinese materia medica preparation for the treatment of insomnia of the present invention, it is characterised in that be made of following raw materials: semen ziziphi spinosae, lily, people
Ginseng, Radix Angelicae Sinensis, Schisandra chinensis.Routinely take orally, pill (water-bindered pill, honeyed bolus, condensed pill, dripping pill), tablet made of liquid preparation technique,
Capsule, granule, pulvis, paste, oral solution and liquid injection agent.
Suggested use and dosage: it is oral, 2 times a day, 3 tablets each time.
It is not suitable for crowd: children, Pregnant and lactant women.
Drug action mechanism of the present invention: semen ziziphi spinosae is the dry mature seed of rhamnaceae plant wild jujube.It is sweet in flavor, sour, it is mild-natured.Return
Liver, gallbladder, the heart channel of Hang-Shaoyin.There is nourishing heart tonifying liver, antitoxic heart-soothing and sedative, arrest sweating, the effect of promoting the production of body fluid.Lily is liliaceous plant lily or spire
The dry meat scale leaf of lily.Sweet in flavor, cold nature, return lung, the heart channel of Hang-Shaoyin have the effect of nourishiing yin to clear away the lung-heat, clearing away the heart fire and tranquillizing.Radix Angelicae Sinensis is
The dry root of umbelliferae angelica.Radix Angelicae Sinensis can promoting circulation of blood unsmooth and the deficiency enriched blood, can make qi and blood that ought be returned, respectively
Its arteries and veins of row, therefore named Radix Angelicae Sinensis.Radix Angelicae Sinensis is sweet in flavor, pungent, warm-natured, returns liver, the heart, the spleen channel, has the effect of replenishing and activating blood.Ginseng is slender acanthopanax
The dry root of section's plant ginseng.Sweet in flavor, slight bitter, it is mild-natured.Returns spleen, lung, the heart, kidney channel.Schisandra chinensis is magnoliaceae schisandra
Dry mature fruit, it is sour, sweet, it is warm-natured.Have the function of astringency inducing, nourishing generate fluid, kidney calming.
Curative effect judgement
Cure: symptom, sign all disappear；Improve: difficulty falling asleep, sleeping time is few, rear difficult sleep of waking up, frequently awakening, dreaminess are easy
The symptoms such as awake disappear substantially；Invalid: symptom, sign are not improved.
Treatment results: capsule of the present invention is taken in treatment insomniac 95,2 times a day, 3 tablets each time, treats for one within 15 days
Journey.Through three course of therapy, 64 are cured, accounts for 67%, is improved 28, is accounted for 29%, invalid 3, account for 4%, total effective rate 96%.Pass through
Without any side effects to patient shown in treatment, three big routine tests and liver and kidney function tests are no abnormal.
The present invention has the following advantages: the present invention is that clinical practice development is combined on the basis of traditional tcm treatment according to syndrome differentiation
Made of, all medicines combine has supplementing qi and nourishing yin altogether, nourishing liver and kidney, antitoxic heart-soothing and sedative, rationally the effect of adjusting internal organs, treatment insomnia
Have the characteristics that curative for effect, quick, cure rate is high, have no toxic side effect.
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Specific embodiment:
The present invention is described further with reference to embodiments.
Embodiment
Capsule weighs raw material in parts by weight: 3-5 parts of semen ziziphi spinosae, 3-5 parts of lily, 3-5 parts of Radix Angelicae Sinensis, 1-2 parts of ginseng,
1-2 parts of Schisandra chinensis.
Capsule preparation method thereof: semen ziziphi spinosae, ginseng, lily, Radix Angelicae Sinensis, Schisandra chinensis distinguish net system, after the assay was approved for preparation
It uses；Take ginseng appropriate, crushed after being dried, sieving sterilizes spare；Semen ziziphi spinosae, Schisandra chinensis, surplus ginseng are taken, ethyl alcohol is added and returns
Stream extracts 2 times.Filtration, merging filtrate (the another device of the dregs of a decoction saves), filtrate recycling ethanol is concentrated into clear cream, spare；Take Radix Angelicae Sinensis, hundred
Conjunction and the above-mentioned alcohol extracting dregs of a decoction, add water to cook 2 times, filter, merging filtrate (dregs of a decoction discard), filtrate decompression is concentrated into relative density
Clear cream, it is spare；Merge above two clear cream, be dried under reduced pressure, crush, sieving, gained cream powder and ginseng fine powder mix, encapsulated.
Tablet weighs raw material in parts by weight: 3-5 parts of semen ziziphi spinosae, 3-5 parts of lily, 3-5 parts of Radix Angelicae Sinensis, 1-2 parts of ginseng, five
1-2 parts of taste.
Method for preparing tablet thereof: semen ziziphi spinosae, ginseng, lily, Radix Angelicae Sinensis, Schisandra chinensis distinguish net system, make after the assay was approved for preparation
With；Take ginseng appropriate, crushed after being dried, sieving sterilizes spare；Semen ziziphi spinosae, Schisandra chinensis, surplus ginseng are taken, alcohol reflux is added
It extracts 2 times.Filtration, merging filtrate (the another device of the dregs of a decoction saves), filtrate recycling ethanol is concentrated into clear cream, spare；Take Radix Angelicae Sinensis, lily
It with the above-mentioned alcohol extracting dregs of a decoction, adds water to cook 2 times, filters, merging filtrate (dregs of a decoction discard), filtrate decompression is concentrated into the clear of relative density
Cream, it is spare；Merge above two clear cream, be dried under reduced pressure, crush, sieving, gained cream powder and ginseng fine powder mix, granulation, tabletting.
Claims (3)
1. a kind of Chinese materia medica preparation for treating insomnia, it is characterised in that be made of the raw material of following parts by weight: 3-5 parts of semen ziziphi spinosae,
3-5 parts of lily, 3-5 parts of Radix Angelicae Sinensis, 1-2 parts of ginseng, 1-2 parts of Schisandra chinensis.
2. the preparation method of the medicament for treating insomnia of claim 1, it is characterised in that comprise the steps of:
(1) semen ziziphi spinosae, ginseng, lily, Radix Angelicae Sinensis, Schisandra chinensis distinguish net system, use after the assay was approved for preparation；
(2) take ginseng appropriate, crushed after being dried, sieving sterilizes spare；
(3) semen ziziphi spinosae, Schisandra chinensis, surplus ginseng are taken, alcohol reflux is added and extracts 2 times, filtration, merging filtrate (protect by the another device of the dregs of a decoction
Deposit), filtrate recycling ethanol is concentrated into clear cream, spare；
(4) Radix Angelicae Sinensis, lily and the above-mentioned alcohol extracting dregs of a decoction are taken, are added water to cook 2 times, are filtered, merging filtrate (dregs of a decoction discard), filtrate decompression
It is concentrated into the clear cream of relative density, it is spare；
(5) merge above two clear cream, be dried under reduced pressure, crush, sieving, gained cream powder and ginseng fine powder mix, and required medicine is made
Agent.
3. a kind of Chinese materia medica preparation for treating insomnia of claim 1, it is characterised in that: routinely take orally, liquid preparation technique system
At pill (water-bindered pill, honeyed bolus, condensed pill, dripping pill), tablet, capsule, granule, pulvis, paste, oral solution or liquid injection
Agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201910476293.3A CN110101789A (en) | 2019-06-05 | 2019-06-05 | The Chinese materia medica preparation for treating insomnia |
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| CN201910476293.3A CN110101789A (en) | 2019-06-05 | 2019-06-05 | The Chinese materia medica preparation for treating insomnia |
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| CN110101789A true CN110101789A (en) | 2019-08-09 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113876881A (en) * | 2021-11-12 | 2022-01-04 | 滨州医学院 | Traditional Chinese medicine composition for improving sleep and preparation method thereof |
| CN114917298A (en) * | 2022-05-07 | 2022-08-19 | 森隆药业有限公司 | Pharmaceutical composition for treating pneumonia and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102940768A (en) * | 2012-09-03 | 2013-02-27 | 吉林一正药业集团有限公司 | Composition for improving sleep and preparation method and application thereof |
-
2019
- 2019-06-05 CN CN201910476293.3A patent/CN110101789A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102940768A (en) * | 2012-09-03 | 2013-02-27 | 吉林一正药业集团有限公司 | Composition for improving sleep and preparation method and application thereof |
Non-Patent Citations (2)
| Title |
|---|
| 方山: "《农业产业化致富丛书（第三辑）人参》", 30 June 1999, 南方出版社 * |
| 林剑: ""安眠汤加味辨证治疗失眠体会"", 《中医临床研究》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113876881A (en) * | 2021-11-12 | 2022-01-04 | 滨州医学院 | Traditional Chinese medicine composition for improving sleep and preparation method thereof |
| CN114917298A (en) * | 2022-05-07 | 2022-08-19 | 森隆药业有限公司 | Pharmaceutical composition for treating pneumonia and preparation method thereof |
| CN114917298B (en) * | 2022-05-07 | 2023-10-20 | 森隆药业有限公司 | Pharmaceutical composition for treating pneumonia and preparation method thereof |
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Application publication date: 20190809 |