CN110090252A - A kind of nursing Special sterilizing liquid - Google Patents

A kind of nursing Special sterilizing liquid Download PDF

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Publication number
CN110090252A
CN110090252A CN201810084513.3A CN201810084513A CN110090252A CN 110090252 A CN110090252 A CN 110090252A CN 201810084513 A CN201810084513 A CN 201810084513A CN 110090252 A CN110090252 A CN 110090252A
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CN
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Prior art keywords
bromochloroin
seng
borneol
alum
kuh
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Pending
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CN201810084513.3A
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Chinese (zh)
Inventor
鲁燕
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Qilu Hospital of Shandong University
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Qilu Hospital of Shandong University
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Priority to CN201810084513.3A priority Critical patent/CN110090252A/en
Publication of CN110090252A publication Critical patent/CN110090252A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of nursing Special sterilizing liquid, including kuh-seng, citric acid, rheum officinale, bromochloroin, dittany bark, two chlordantoins, wrinkled giant hyssop, C5H6Br2N2O2, Fructus meliae toosendan, semen brassicae, alum, benzalkonium bromide, borneol and distilled water.Compared with prior art, Chinese and Western of the present invention combines, and is extracted using traditional Chinese medicine ingredients, and in conjunction with a small amount of chemical thimerosal, ingredient is mild, not spirituosity, can not only kill bacterium, additionally it is possible to which, conducive to the healing of skin wound, antiallergy has the value of popularization and application.

Description

A kind of nursing Special sterilizing liquid
Technical field
The present invention relates to medical medicine technical field more particularly to a kind of nursing Special sterilizing liquid.
Background technique
Thimerosal refers to for killing pathogenic microorganism on communication media, reaches the preparation of innoxious requirement, it is not It is same as antibiotic, its main function in diseases prevention is to eliminate pathogenic microorganism except human body, cuts off the propagation of infectious disease Approach achievees the purpose that control infectious disease.In the prior art, most of to be carried out disinfection with alcohol, there are also some chemical disinfection liquid, But chemical disinfection liquid smell is relatively more pungent, is only applicable to object and environment disinfected, and is not suitable for patient skin disinfection, in addition, having A little patient's alcohol intolerances can not use alcohol disinfecting, and therefore, it is necessary to a kind of new thimerosals.
Summary of the invention
The object of the invention is that providing a kind of nursing Special sterilizing liquid to solve the above-mentioned problems.
The present invention through the following technical solutions to achieve the above objectives:
The present invention includes kuh-seng, citric acid, rheum officinale, bromochloroin, dittany bark, two chlordantoins, wrinkled giant hyssop, C5H6Br2N2O2, river Chinaberry, semen brassicae, alum, benzalkonium bromide, borneol and distilled water.By weight, contain the kuh-seng 15-25g, the lemon for every part Sour 4-8g, the rheum officinale 20-30g, the bromochloroin 1-3g, the dittany bark 25-30g, the two chlordantoins 0.5-1g, institute State wrinkled giant hyssop 15-25g, the C5H6Br2N2O2 1-3g, the Fructus meliae toosendan 10-15g, the semen brassicae 10-20g, the alum 15- 25g, the benzalkonium bromide 0.1-0.5g, the borneol 10-15g, the distilled water 500-600g.
By weight, contain the kuh-seng 20g, the citric acid 5g, the rheum officinale 25g, the bromochloroin 2g, institute for every part State dittany bark 30g, the two chlordantoins 0.5g, the wrinkled giant hyssop 20g, the C5H6Br2N2O2 1.5g, the Fructus meliae toosendan 15g, described Semen brassicae 15g, the alum 20g, the benzalkonium bromide 0.2g, the borneol 12g, the distilled water 500g.
Production method of the present invention the following steps are included:
(1) it is placed in container after weighing kuh-seng, rheum officinale, dittany bark, wrinkled giant hyssop, Fructus meliae toosendan, semen brassicae by weight, is added 4 Amount pure water is boiled again；
(2) it is filtered after the pure water that 4 times are measured being boiled remaining 2 times of amounts；It takes concoction spare；
(3) decoction is clarified, takes half supernatant spare after clarification；
(4) by citric acid, bromochloroin, two chlordantoins, C5H6Br2N2O2, alum, benzalkonium bromide, borneol and distilled water with The supernatant that step (3) obtains mixes up to thimerosal finished product.
The beneficial effects of the present invention are:
The present invention is a kind of nursing Special sterilizing liquid, and compared with prior art, Chinese and Western of the present invention combines, using traditional Chinese medicine ingredients Extraction, in conjunction with a small amount of chemical thimerosal, ingredient is mild, not spirituosity, can not only kill bacterium, additionally it is possible to be conducive to skin and hurt The healing of mouth, antiallergy have the value of popularization and application.
Specific embodiment
The invention will be further described below:
The present invention includes kuh-seng, citric acid, rheum officinale, bromochloroin, dittany bark, two chlordantoins, wrinkled giant hyssop, C5H6Br2N2O2, river Chinaberry, semen brassicae, alum, benzalkonium bromide, borneol and distilled water.By weight, contain the kuh-seng 15-25g, the lemon for every part Sour 4-8g, the rheum officinale 20-30g, the bromochloroin 1-3g, the dittany bark 25-30g, the two chlordantoins 0.5-1g, institute State wrinkled giant hyssop 15-25g, the C5H6Br2N2O2 1-3g, the Fructus meliae toosendan 10-15g, the semen brassicae 10-20g, the alum 15- 25g, the benzalkonium bromide 0.1-0.5g, the borneol 10-15g, the distilled water 500-600g.
By weight, contain the kuh-seng 20g, the citric acid 5g, the rheum officinale 25g, the bromochloroin 2g, institute for every part State dittany bark 30g, the two chlordantoins 0.5g, the wrinkled giant hyssop 20g, the C5H6Br2N2O2 1.5g, the Fructus meliae toosendan 15g, described Semen brassicae 15g, the alum 20g, the benzalkonium bromide 0.2g, the borneol 12g, the distilled water 500g.
Production method of the present invention the following steps are included:
(1) it is placed in container after weighing kuh-seng, rheum officinale, dittany bark, wrinkled giant hyssop, Fructus meliae toosendan, semen brassicae by weight, is added 4 Amount pure water is boiled again；
(2) it is filtered after the pure water that 4 times are measured being boiled remaining 2 times of amounts；It takes concoction spare；
(3) decoction is clarified, takes half supernatant spare after clarification；
(4) by citric acid, bromochloroin, two chlordantoins, C5H6Br2N2O2, alum, benzalkonium bromide, borneol and distilled water with The supernatant that step (3) obtains mixes up to thimerosal finished product.
Embodiment one:
Kuh-seng 20g, citric acid 5g, rheum officinale 25g, bromochloroin 2g, dittany bark 30g, two chlordantoin 0.5g, wrinkled giant hyssop according to the ratio 20g, C5H6Br2N2O2 1.5g, Fructus meliae toosendan 15g, semen brassicae 15g, alum 20g, benzalkonium bromide 0.2g, borneol 12g, distilled water 500g, It uses thimerosal experimental data made of method of the invention as follows: measuring pH value as 6.71, action time 10min, for withered The microbial load of careless bacillus declines 6.5 log.
Embodiment two:
Kuh-seng 22g, citric acid 6g, rheum officinale 30g, bromochloroin 3g, dittany bark 30g, two chlordantoin 0.8g, wrinkled giant hyssop according to the ratio 25g, C5H6Br2N2O2 2.5g, Fructus meliae toosendan 12g, semen brassicae 20g, alum 25g, benzalkonium bromide 0.5g, borneol 15g, distilled water 600g, It uses thimerosal experimental data made of method of the invention as follows: measuring pH value as 6.57, action time 10min, for withered The microbial load of careless bacillus declines 7.1 log.
Basic principles and main features and advantages of the present invention of the invention have been shown and described above.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its Equivalent thereof.

Claims (4)

1. a kind of nursing Special sterilizing liquid, it is characterised in that: including kuh-seng, citric acid, rheum officinale, bromochloroin, dittany bark, dichloro Glycolylurea, wrinkled giant hyssop, C5H6Br2N2O2, Fructus meliae toosendan, semen brassicae, alum, benzalkonium bromide, borneol and distilled water.
2. nursing Special sterilizing liquid according to claim 1, it is characterised in that: by weight, every part contains the kuh-seng 15- 25g, the citric acid 4-8g, the rheum officinale 20-30g, the bromochloroin 1-3g, the dittany bark 25-30g, the dichloro Glycolylurea 0.5-1g, the wrinkled giant hyssop 15-25g, the C5H6Br2N2O2 1-3g, the Fructus meliae toosendan 10-15g, the semen brassicae 10-20g, The alum 15-25g, the benzalkonium bromide 0.1-0.5g, the borneol 10-15g, the distilled water 500-600g.
3. nursing Special sterilizing liquid according to claim 2, it is characterised in that: by weight, every part contains the kuh-seng 20g, the citric acid 5g, the rheum officinale 25g, the bromochloroin 2g, the dittany bark 30g, the two chlordantoins 0.5g, institute It states wrinkled giant hyssop 20g, the C5H6Br2N2O2 1.5g, the Fructus meliae toosendan 15g, the semen brassicae 15g, the alum 20g, the benzene and pricks bromine Ammonium 0.2g, the borneol 12g, the distilled water 500g.
4. nursing Special sterilizing liquid according to claim 1, it is characterised in that: production method the following steps are included:
(1) it is placed in container after weighing kuh-seng, rheum officinale, dittany bark, wrinkled giant hyssop, Fructus meliae toosendan, semen brassicae by weight, 4 times of amounts is added Pure water is boiled；
(2) it is filtered after the pure water that 4 times are measured being boiled remaining 2 times of amounts；It takes concoction spare；
(3) decoction is clarified, takes half supernatant spare after clarification；
(4) and step by citric acid, bromochloroin, two chlordantoins, C5H6Br2N2O2, alum, benzalkonium bromide, borneol and distilled water (3) supernatant obtained mixes up to thimerosal finished product.
CN201810084513.3A 2018-01-29 2018-01-29 A kind of nursing Special sterilizing liquid Pending CN110090252A (en)

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CN110090252A true CN110090252A (en) 2019-08-06

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110406185A (en) * 2019-08-13 2019-11-05 山东省医学科学院附属医院 A kind of nursing of air-permeable anti-bacterial Wound dressings production method
CN110638889A (en) * 2019-09-04 2020-01-03 傅云其 Formula and preparation method of special disinfectant for acupuncture and moxibustion
CN110680735A (en) * 2019-09-04 2020-01-14 傅云其 Acupuncture needle strorage device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104840647A (en) * 2015-05-11 2015-08-19 李彦霞 Gynecology cleaning detergent formula

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104840647A (en) * 2015-05-11 2015-08-19 李彦霞 Gynecology cleaning detergent formula

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110406185A (en) * 2019-08-13 2019-11-05 山东省医学科学院附属医院 A kind of nursing of air-permeable anti-bacterial Wound dressings production method
CN110638889A (en) * 2019-09-04 2020-01-03 傅云其 Formula and preparation method of special disinfectant for acupuncture and moxibustion
CN110680735A (en) * 2019-09-04 2020-01-14 傅云其 Acupuncture needle strorage device

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Application publication date: 20190806