CN110064033A - 一种止咳化痰凝血的药物组合物及其制备方法 - Google Patents

一种止咳化痰凝血的药物组合物及其制备方法 Download PDF

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CN110064033A
CN110064033A CN201910419938.XA CN201910419938A CN110064033A CN 110064033 A CN110064033 A CN 110064033A CN 201910419938 A CN201910419938 A CN 201910419938A CN 110064033 A CN110064033 A CN 110064033A
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吴国生
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Abstract

本发明公开了一种止咳化痰凝血的药物组合物及其制备方法，按重量份计，其原料包括如下组份：款冬15‑30份、胯杷果15‑35份、泡制山药20‑30份、浙贝母10‑15份、半夏5‑15份、白芥子20‑28份、瓜篓皮25‑35份、蜜制百合25‑48份、车前草10‑20份、紫菀15‑20份、鱼腥草10‑18份、桔梗8‑18份、薄荷12‑20份、厚朴15‑20份、蒲公英10‑17份、桑白皮12‑18份、葶苈子10‑20份、枳实5‑12份、百部7‑15份、五味子10‑15份。本发明采用上述组份原料配比的药物，综合了各味中药的药效，合理搭配协同增效，使止咳化痰的效果得到增强，对慢性气管炎，支气管扩张引起的咳嗽痰多，且痰中带血，呼吸不畅，胸闷效果明显，而且起效快，无明显副作用，具有很好的止咳化痰凝血的效果。

Description

一种止咳化痰凝血的药物组合物及其制备方法
技术领域
本发明涉及一种采用中药治疗咳嗽咳血的药物组合物及其制备方法。
背景技术
由于肺部病变引起的肺炎、支气管炎、支气管扩张发作时，常出现咳嗽、痰多、气喘以致于发生咳血症状，病症久治不愈。目前呼吸道疾病用药的品种比较多，但其疗效都有所欠缺，西药的止咳药偏重于镇咳祛痰，且多含有麻醉成份，副作用较大，中成药如桔梗止咳片、蛇胆川贝液等随着使用时间的延长，治疗效果不再明显，需要更换药物进行治疗。
发明内容
本发明的目的就是为了解决以上问题，提供一种疗效好的止咳化痰凝血的药物组合物及其制备方法。
本发明止咳化痰凝血的药物组合物按重量份计，其原料包括如下组份：
款冬15-30份、胯杷果15-35份、泡制山药20-30份、浙贝母10-15份、半夏5-15份、白芥子20-28份、瓜篓皮25-35份、蜜制百合25-48份、车前草10-20份、紫菀15-20份、鱼腥草10-18份、桔梗8-18份、薄荷12-20份、厚朴15-20份、蒲公英10-17份、桑白皮12-18份、葶苈子10-20份、枳实5-12份、百部7-15份、五味子10-15份。
作为优选，本发明药物组合物按重量份计，其原料包括如下组份：款冬23 g、胯杷果20 g、泡制山药25 g、浙贝母15 g、半夏10 g、白芥子25 g、瓜蒌皮30 g、蜜制百合30 g、车前草20 g、紫菀18 g、鱼腥草17 g、桔梗15 g、薄荷17 g、厚朴20 g、蒲公英15 g、桑白皮15g、葶苈子18 g、枳实10 g、百部12 g、五味子15 g。
制备上述药物组合物的方法：
泡制山药制法：山药1000克放入黄酒500ml、冰糖200克，密封泡制7天后，取出晾干，即得泡制山药。
蜜制百合制法：百合300克放入蜂蜜200克、水500ml，密封3天后取出晾干，即得蜜制百合。
将上述各种原料组份干燥、粉碎后按上述比例混合均匀，即得到本发明药物组合物药粉。
用法及用量：将混合药粉装入胶囊，每次服用600-900mg，一天三次，饭后服用，如果同西药一起服用，需与西药间隔半小时为宜。一般服用3-7天即可见效。也可将辅料添加入药粉混合物中，混合均匀，压片，即得到中药片剂，其中药粉混合物与辅料的质量比为1：0.1，辅料可选用淀粉、糊精和蔗糖。
各原料组份功效作用：
款冬：润肺下气、化痰止咳
胯杷果（金银忍冬果实）：镇咳凝血
泡制山药：止咳化痰，预防感冒效果很好
浙贝母：清热润肺，散结解毒
半夏：养阴清肺，化痰缓喘
白芥子：止咳平喘，散结消肿
瓜蒌皮：清肺化痰，利气散结
蜜制百合：镇咳祛痰，滋阴润肺
车前草：清肺化痰
紫菀：温肺下气，消痰止咳
鱼腥草：消痈排脓
桔梗：祛痰排脓
薄荷：发散风热，清头目
厚朴：燥湿消痰，下气除满
蒲公英：清热解毒，消炎
桑白皮：肺热咳嗽，喘逆痰多
葶苈子：泻肺平喘，行水消肿
枳实：化痰散痞，破气消积
百部：润肺下气止咳消炎
五味子：止咳平喘，敛肺气
本发明采用上述组份原料配比的药物，综合了各味中药的药效，合理搭配协同增效，使止咳化痰的效果得到增强，而且起效快，无明显副作用，具有很好的止咳化痰凝血的效果。病发初期：因感染引起的肺部不适，有炎症，咳嗽，少量痰，及鼻塞流鼻涕，一般3天为一疗程。病史较长：如慢性气管炎，支气管扩张引起的肺部呼吸困难，气喘，咳嗽脓痰且痰中带血，一般7-10天为一疗程。本发明药物对慢性气管炎，支气管扩张引起的咳嗽痰多，且痰中带血，呼吸不畅，胸闷效果明显，服用1-3天症状好转。
具体实施方式
泡制山药：山药1000克放入黄酒500ml、冰糖200克，密封泡制7天后，取出晾干，即得泡制山药。
蜜制百合：百合300克放入蜂蜜200克、水500ml，密封3天后取出晾干，即得蜜制百合。
实施例1： 取款冬15g、胯杷果15g、泡制山药20g、浙贝母10g、半夏5 g、白芥子20g、瓜蒌皮25 g、蜜制百合25 g、车前草10 g、紫菀15 g、鱼腥草10 g、桔梗8 g、薄荷12 g、厚朴15 g、蒲公英10 g、桑白皮12 g、葶苈子10 g、枳实5 g、百部7 g、五味子10 g，将上述各原料烘干至含水量低于 5% 后，分别粉碎至过 20 目筛的粗粉，然后混合装入胶囊服用。一天三次，每次饭后服用600mg。
治疗病患对症：咳嗽有痰，鼻塞流鼻涕，肺部有轻微炎症。服用当天即可起效，3天为一疗程，症状明显好转。
实施例2： 取款冬23 g、胯杷果20 g、泡制山药25 g、浙贝母15 g、半夏10 g、白芥子25 g、瓜蒌皮30 g、蜜制百合30 g、车前草20 g、紫菀18 g、鱼腥草17 g、桔梗15 g、薄荷17g、厚朴20 g、蒲公英15 g、桑白皮15 g、葶苈子18 g、枳实10 g、百部12 g、五味子15 g。
将上述各原料烘干至含水量低于 5% 后，分别粉碎至过 20 目筛的粗粉，然后混合装入胶囊服用。一天三次，每次饭后服用600mg。
治疗病患对症：对咳嗽，黄脓痰，痰中带血，或由慢性气管炎引起的呼吸不畅，胸闷气喘，效果俱佳，服用当天即可起效，本实施例为症状时间较长，病情严重的患者，7-10天为一疗程。
实施例3：款冬30份、胯杷果35份、泡制山药30份、浙贝母15份、半夏15份、白芥子28份、瓜篓皮35份、蜜制百合48份、车前草20份、紫菀20份、鱼腥草18份、桔梗18份、薄荷20份、厚朴20份、蒲公英17份、桑白皮18份、葶苈子20份、枳实12份、百部15份、五味子10-15份。
将上述各原料烘干至含水量低于 5% 后，分别粉碎至过 20 目筛的粗粉，然后混合装入胶囊服用。一天三次，每次饭后服用600mg，5天为一疗程。
本实施例对呼吸困难，离不开氧气，咳嗽痰中带血的重病患者，治疗效果会更好，疗程更短，服用当天，病情明显好转，呼吸顺畅，晚上很少咳嗽了，睡觉很好，7天后，痰中带血的症状彻底消失。

Claims (3)

1.一种止咳化痰凝血的药物组合物，其特征在于，按重量份计，其原料包括如下组份：款冬15-30份、胯杷果15-35份、泡制山药20-30份、浙贝母10-15份、半夏5-15份、白芥子20-28份、瓜篓皮25-35份、蜜制百合25-48份、车前草10-20份、紫菀15-20份、鱼腥草10-18份、桔梗8-18份、薄荷12-20份、厚朴15-20份、蒲公英10-17份、桑白皮12-18份、葶苈子10-20份、枳实5-12份、百部7-15份、五味子10-15份。
2.根据权利要求1所述的药物组合物，其特征在于，按重量份计，其原料包括如下组份：款冬23 g、胯杷果20 g、泡制山药25 g、浙贝母15 g、半夏10 g、白芥子25 g、瓜蒌皮30 g、蜜制百合30 g、车前草20 g、紫菀18 g、鱼腥草17 g、桔梗15 g、薄荷17 g、厚朴20 g、蒲公英15g、桑白皮15 g、葶苈子18 g、枳实10 g、百部12 g、五味子15 g。
3.制备权利要求1或2所述的止咳化痰凝血的药物组合物的方法，其特征在于：将山药1000克放入黄酒500ml、冰糖200克，密封泡制7天后，取出晾干，即得泡制山药；将百合300克放入蜂蜜200克、水500ml，密封3天后取出晾干，即得蜜制百合；将所述各种原料组份干燥、粉碎后按上述比例混合均匀，即得到本发明药物组合物。
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