CN110058004A - A kind of experimental provision of laser co-focusing detection electro photoluminescence safety - Google Patents

A kind of experimental provision of laser co-focusing detection electro photoluminescence safety Download PDF

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Publication number
CN110058004A
CN110058004A CN201910288724.3A CN201910288724A CN110058004A CN 110058004 A CN110058004 A CN 110058004A CN 201910288724 A CN201910288724 A CN 201910288724A CN 110058004 A CN110058004 A CN 110058004A
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electro photoluminescence
laser
fixedly connected
detection
experimental provision
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高权
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/4833Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses a kind of experimental provisions of laser co-focusing detection electro photoluminescence safety, including experimental bench, the left side top of the experimental bench is provided with detection block, electric stimulating instrument is provided in the middle part of the experimental bench, the right hand top of the experimental bench is provided with computer, the bottom of the electric stimulating instrument is fixedly connected with support base, and the surface of the electric stimulating instrument is provided with display screen, and the present invention relates to medical equipment technical fields.A kind of experimental provision of laser co-focusing detection electro photoluminescence safety, having reached will test sample and is placed on electro photoluminescence experiment porch, it is contacted again with electro photoluminescence contact with detection sample, carry out electro photoluminescence, laser confocal microscope is recycled to record the physiological phenomenon that electro photoluminescence generates, pass through computerized three-dimensional reconstruction software support, obtain 3-D image, the tissue solid shape and spatial relationship of observing response detection sample, improve the accuracy of detection, error is small, improves the purpose of detection electro photoluminescence security work efficiency.

Description

A kind of experimental provision of laser co-focusing detection electro photoluminescence safety
Technical field
The present invention relates to medical equipment technical field, specially a kind of experiment of laser co-focusing detection electro photoluminescence safety Device.
Background technique
Neuromuscular electric stimulation therapy, which is one, makes its pumping by electrode stimulating specific muscle group using 20-50Hz low-frequency current It jerks or shrinks, then reach the technology of " function " reparation.
People are when carrying out the various researchs in medicine and field of biology, it is sometimes desirable to observe stimulant to the work of receptor With to carry out various medicine and biological test, detection, production and clinical treatment.It has used in the prior art a kind of known Electrical stimulation device observe receptor to the reflection after stimulating electrode effect, directly to be acted on by the Neural stimulation electrodes Screening and pharmacological research are carried out in the drug of receptor.
Existing neuromuscular electric stimulation therapy needs largely to be tested in use, detection electro photoluminescence safety Property, existing detection device, detection effect is inaccurate, and there is a certain error, is unable to satisfy use demand.
Summary of the invention
(1) the technical issues of solving
In view of the deficiencies of the prior art, the present invention provides a kind of experiment dresses of laser co-focusing detection electro photoluminescence safety It sets, solves neuromuscular electric stimulation therapy, in use, need largely to be tested, detect electro photoluminescence safety, it is existing Detection device, detection effect is inaccurate, and there is a certain error, the problem of being unable to satisfy use demand.
(2) technical solution
In order to achieve the above object, the present invention is achieved by the following technical programs: a kind of laser co-focusing detection electricity thorn Swash the experimental provision of safety, including experimental bench, the left side top of the experimental bench is provided with detection block, in the experimental bench Portion is provided with electric stimulating instrument, and the right hand top of the experimental bench is provided with computer, and the bottom of the electric stimulating instrument is fixedly connected There is support base, the surface of the electric stimulating instrument is provided with display screen, and indicator light is provided with below the display screen, described aobvious Switch is provided on the left of display screen, the lower section of the display screen, which is located on the left of indicator light, is provided with vernier knob, the electricity thorn The bottom for swashing instrument is provided with electro photoluminescence output end, and the electro photoluminescence output end is fixedly connected with conducting wire, the surface of the detection block It is provided with laser confocal microscope, the side of the laser confocal microscope is provided with data line, the bottom of the detection block Portion is provided with support frame, and the central bottom of the detection block is fixedly connected with bottom frame, is fixedly connected with liquid at the top of the bottom frame Extension stem to be pressed, is fixedly connected with motion platform at the top of the hydraulically extensible stick, the motion platform is slidably connected with detection block, Electro photoluminescence experiment porch is fixedly connected at the top of the motion platform, two lateral roofs of the motion platform are fixedly connected with side Plate, the side of the side plate are fixedly connected with fine tuning expansion bracket, and the output end of the fine tuning expansion bracket is fixedly connected with grip block, It is fixedly connected with limited block at the top of the grip block, conducting wire fixed block is provided with above the limited block, the conducting wire is solid Determine block to be fixedly connected with conducting wire, the bottom of the conducting wire fixed block is fixedly connected with slide bar, and the slide bar and limited block sliding connect It connects, the bottom of the slide bar is fixedly connected with fixed block, and the bottom of the fixed block is fixedly connected with spring bracing, the bullet The bottom of spring support frame is fixedly connected with spring, and the bottom of the spring is fixedly connected with electro photoluminescence contact.
Preferably, the quantity of the electro photoluminescence contact is two, and the electro photoluminescence contact is located at laser confocal microscope Left side is anode, and it is cathode that the electro photoluminescence contact, which is located on the right side of laser confocal microscope,.
Preferably, the laser confocal microscope is connected to a computer by data line.
Preferably, the top plate of the electro photoluminescence experiment porch is provided with detection sample.
Preferably, the laser confocal microscope is corresponding with electro photoluminescence experiment porch position.
Preferably, the spring is in compressive state.
Preferably, the electro photoluminescence contact is patch motor.
Preferably, the electric stimulating instrument range of current output is 1.0mA to 20.0mA.
Preferably, the laser confocal microscope sweeps stress reaction of the detection sample under electric stimulating instrument effect Record is traced, and is come out by Computer display.
Preferably, the maximum height of the electro photoluminescence experiment porch and laser confocal microscope are contactless.
(3) beneficial effect
The present invention provides a kind of experimental provisions of laser co-focusing detection electro photoluminescence safety.Have following beneficial to effect Fruit:
(1), the experimental provision of laser co-focusing detection electro photoluminescence safety, is provided with by the left side top of experimental bench Detection block is provided with electric stimulating instrument in the middle part of experimental bench, and the right hand top of experimental bench is provided with computer, the bottom of electric stimulating instrument It is fixedly connected with support base, the surface of electric stimulating instrument is provided with display screen, indicator light, display screen are provided with below display screen Left side be provided with switch, the lower section of display screen, which is located on the left of indicator light, is provided with vernier knob, and the bottom of electric stimulating instrument is set It is equipped with electro photoluminescence output end, electro photoluminescence output end is fixedly connected with conducting wire, and it is micro- that the surface of detection block is provided with laser co-focusing Mirror, the side of laser confocal microscope are provided with data line, and the bottom of detection block is provided with support frame, the intermediate bottom of detection block Portion is fixedly connected with bottom frame, and hydraulically extensible stick is fixedly connected at the top of bottom frame, fortune is fixedly connected at the top of hydraulically extensible stick Moving platform, motion platform are slidably connected with detection block, and electro photoluminescence experiment porch is fixedly connected at the top of motion platform, and movement is flat Two lateral roofs of platform are fixedly connected with side plate, and the side of side plate is fixedly connected with fine tuning expansion bracket, finely tune the output end of expansion bracket It is fixedly connected with grip block, limited block is fixedly connected at the top of grip block, conducting wire fixed block is provided with above limited block, is led Line fixed block is fixedly connected with conducting wire, and the bottom of conducting wire fixed block is fixedly connected with slide bar, and slide bar is slidably connected with limited block, sliding The bottom of bar is fixedly connected with fixed block, and the bottom of fixed block is fixedly connected with spring bracing, and the bottom of spring bracing is solid Surely be connected with spring, the bottom of spring is fixedly connected with electro photoluminescence contact, reached will test sample be placed on electro photoluminescence experiment On platform, then with electro photoluminescence contact with detection sample contacted, carry out electro photoluminescence, recycle laser confocal microscope will be electric The physiological phenomenon that stimulation generates is recorded, and by computerized three-dimensional reconstruction software support, obtains 3-D image, observing response inspection The tissue solid shape and spatial relationship of test sample sheet, improve the accuracy of detection, and error is small, improve detection electro photoluminescence safety work Make the purpose of efficiency.
Detailed description of the invention
Fig. 1 is overall structure of the present invention;
Fig. 2 is electric stimulating instrument structural schematic diagram of the present invention;
Fig. 3 is detection block structural schematic diagram of the present invention;
Fig. 4 is A-A structural schematic diagram of the present invention;
Fig. 5 is workflow block diagram of the present invention.
In figure: 1 experimental bench, 2 detection blocks, 3 electric stimulating instruments, 4 computers, 5 support bases, 6 display screens, 7 indicator lights, 8 are opened Pass, 9 vernier knobs, 10 electro photoluminescence output ends, 11 conducting wires, 12 laser confocal microscopes, 13 data lines, 14 support frames, 15 bottoms Frame, 16 hydraulically extensible sticks, 17 motion platforms, 18 electro photoluminescence experiment porch, 19 side plates, 20 fine tuning expansion brackets, 21 grip blocks, 22 limits Position block, 23 conducting wire fixed blocks, 24 slide bars, 25 fixed blocks, 26 spring bracings, 27 springs, 28 electro photoluminescence contacts.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
Fig. 1-5 is please referred to, the present invention provides a kind of technical solution: a kind of reality of laser co-focusing detection electro photoluminescence safety Experiment device, including experimental bench 1, the left side top of experimental bench 1 are provided with detection block 2, and the middle part of experimental bench 1 is provided with electric stimulating instrument 3, the right hand top of experimental bench 1 is provided with computer 4, and the bottom of electric stimulating instrument 3 is fixedly connected with support base 5, electric stimulating instrument 3 Surface be provided with display screen 6, the lower section of display screen 6 is provided with indicator light 7, and the left side of display screen 6 is provided with switch 8, display The left side that the lower section of screen 6 is located at indicator light 7 is provided with vernier knob 9, and the bottom of electric stimulating instrument 3 is provided with electro photoluminescence output end 10, electro photoluminescence output end 10 is fixedly connected with conducting wire 11, and the surface of detection block 2 is provided with laser confocal microscope 12, laser The side of Laser Scanning Confocal Microscope 12 is provided with data line 13, and the bottom of detection block 2 is provided with support frame 14, the centre of detection block 2 Bottom is fixedly connected with bottom frame 15, and the top of bottom frame 15 is fixedly connected with hydraulically extensible stick 16, and the top of hydraulically extensible stick 16 is solid Surely it is connected with motion platform 17, motion platform 17 is slidably connected with detection block 2, and the top of motion platform 17 is fixedly connected with electric thorn Swash experiment porch 18, two lateral roofs of motion platform 17 are fixedly connected with side plate 19, and the side of side plate 19 is fixedly connected with fine tuning The output end of expansion bracket 20, fine tuning expansion bracket 20 is fixedly connected with grip block 21, and the top of grip block 21 is fixedly connected with limit Block 22, the top of limited block 22 are provided with conducting wire fixed block 23, and conducting wire fixed block 23 is fixedly connected with conducting wire 11, conducting wire fixed block 23 bottom is fixedly connected with slide bar 24, and slide bar 24 is slidably connected with limited block 22, and the bottom of slide bar 24 is fixedly connected with fixation Block 25, the bottom of fixed block 25 are fixedly connected with spring bracing 26, and the bottom of spring bracing 26 is fixedly connected with spring 27, The bottom of spring 27 is fixedly connected with electro photoluminescence contact 28, and having reached will test sample and be placed on electro photoluminescence experiment porch, then It is contacted with electro photoluminescence contact with detection sample, carries out electro photoluminescence, laser confocal microscope is recycled to generate electro photoluminescence Physiological phenomenon record, by computerized three-dimensional reconstruction software support, obtain 3-D image, observing response detects sample Solid shape and spatial relationship are organized, the accuracy of detection is improved, error is small, improves detection electro photoluminescence security work efficiency Purpose, the quantity of electro photoluminescence contact 28 are two, and it is anode that electro photoluminescence contact 28, which is located at 12 left side of laser confocal microscope, It is cathode that electro photoluminescence contact 28, which is located at 12 right side of laser confocal microscope, and laser confocal microscope 12 passes through data line 13 It is connected with computer 4, the top plate of electro photoluminescence experiment porch 18 is provided with detection sample, and laser confocal microscope 12 and electricity pierce It is corresponding to swash 18 position of experiment porch, spring 27 is in compressive state, and electro photoluminescence contact 28 is patch motor, 3 electricity of electric stimulating instrument Stream output area is 1.0mA to 20.0mA, 12 pairs of laser confocal microscope detection samples under the effect of electric stimulating instrument 3 stress Reaction is scanned record, and is come out by Computer display, the maximum height and laser co-focusing of electro photoluminescence experiment porch 18 Microscope 12 is contactless.
In use, sample to be detected is placed on electro photoluminescence experiment porch 18, two electro photoluminescence contacts 28 and detection sample Originally it is in contact, hydraulically extensible stick 16 works, and drives motion platform 17 to move, adjusts certain height, aobvious convenient for laser co-focusing Micro mirror 12 is observed, while adjusting vernier knob 9, adjusts the output electric current of electric stimulating instrument 3, is carried out electro photoluminescence to detection sample, is swashed The physiological reaction that light Laser Scanning Confocal Microscope 12 will test sample generation is recorded, and is shown by computer, is facilitated people Detect electro photoluminescence safety, having reached will test sample and is placed on electro photoluminescence experiment porch, then with electro photoluminescence contact with detect Sample is contacted, and electro photoluminescence is carried out, and laser confocal microscope is recycled to record the physiological phenomenon that electro photoluminescence generates, By computerized three-dimensional reconstruction software support, 3-D image is obtained, observing response detects tissue solid shape and the space of sample Relationship improves the accuracy of detection, and error is small, improves the purpose of detection electro photoluminescence security work efficiency.
It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment Intrinsic element.In the absence of more restrictions.By sentence " element limited including one ..., it is not excluded that There is also other identical elements in the process, method, article or apparatus that includes the element ".
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (10)

1. a kind of experimental provision of laser co-focusing detection electro photoluminescence safety, including experimental bench (1), it is characterised in that: described The left side top of experimental bench (1) is provided with detection block (2), is provided with electric stimulating instrument (3) in the middle part of the experimental bench (1), described The right hand top of experimental bench (1) is provided with computer (4), and the bottom of the electric stimulating instrument (3) is fixedly connected with support base (5), the surface of the electric stimulating instrument (3) is provided with display screen (6), is provided with indicator light (7) below the display screen (6), It is provided with switch (8) on the left of the display screen (6), the lower section of the display screen (6), which is located on the left of indicator light (7), to be provided with The bottom of vernier knob (9), the electric stimulating instrument (3) is provided with electro photoluminescence output end (10), the electro photoluminescence output end (10) It is fixedly connected with conducting wire (11), the surface of the detection block (2) is provided with laser confocal microscope (12), the laser copolymerization The side of focusing microscope (12) is provided with data line (13), and the bottom of the detection block (2) is provided with support frame (14), the inspection The central bottom for surveying frame (2) is fixedly connected with bottom frame (15), is fixedly connected with hydraulically extensible stick at the top of the bottom frame (15) (16), it is fixedly connected with motion platform (17) at the top of the hydraulically extensible stick (16), the motion platform (17) and detection block (2) it is slidably connected, is fixedly connected with electro photoluminescence experiment porch (18), the motion platform at the top of the motion platform (17) (17) two lateral roofs are fixedly connected with side plate (19), and the side of the side plate (19) is fixedly connected with fine tuning expansion bracket (20), The output end of fine tuning expansion bracket (20) is fixedly connected with grip block (21), is fixedly connected at the top of the grip block (21) Limited block (22) is provided with conducting wire fixed block (23) above the limited block (22), the conducting wire fixed block (23) and conducting wire (11) it is fixedly connected, the bottom of the conducting wire fixed block (23) is fixedly connected with slide bar (24), the slide bar (24) and limited block (22) it is slidably connected, the bottom of the slide bar (24) is fixedly connected with fixed block (25), and the bottom of the fixed block (25) is fixed It is connected with spring bracing (26), the bottom of the spring bracing (26) is fixedly connected with spring (27), the spring (27) Bottom be fixedly connected with electro photoluminescence contact (28).
2. a kind of experimental provision of laser co-focusing detection electro photoluminescence safety according to claim 1, it is characterised in that: The quantity of the electro photoluminescence contact (28) is two, and the electro photoluminescence contact (28) is located on the left of laser confocal microscope (12) It is anode, it is cathode that the electro photoluminescence contact (28), which is located on the right side of laser confocal microscope (12),.
3. a kind of experimental provision of laser co-focusing detection electro photoluminescence safety according to claim 1, it is characterised in that: The laser confocal microscope (12) is connected by data line (13) with computer (4).
4. a kind of experimental provision of laser co-focusing detection electro photoluminescence safety according to claim 1, it is characterised in that: The top plate of the electro photoluminescence experiment porch (18) is provided with detection sample.
5. a kind of experimental provision of laser co-focusing detection electro photoluminescence safety according to claim 1, it is characterised in that: The laser confocal microscope (12) is corresponding with electro photoluminescence experiment porch (18) position.
6. a kind of experimental provision of laser co-focusing detection electro photoluminescence safety according to claim 1, it is characterised in that: The spring (27) is in compressive state.
7. a kind of experimental provision of laser co-focusing detection electro photoluminescence safety according to claim 1, it is characterised in that: The electro photoluminescence contact (28) is patch motor.
8. a kind of experimental provision of laser co-focusing detection electro photoluminescence safety according to claim 1, it is characterised in that: Electric stimulating instrument (3) range of current output is 1.0mA to 20.0mA.
9. a kind of experimental provision of laser co-focusing detection electro photoluminescence safety according to claim 1, it is characterised in that: The laser confocal microscope (12) is scanned record to stress reaction of the detection sample under electric stimulating instrument (3) effect, And it is come out by Computer display.
10. a kind of experimental provision of laser co-focusing detection electro photoluminescence safety according to claim 1, feature exist In: the maximum height and laser confocal microscope (12) of the electro photoluminescence experiment porch (18) are contactless.
CN201910288724.3A 2019-04-11 2019-04-11 A kind of experimental provision of laser co-focusing detection electro photoluminescence safety Pending CN110058004A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111505006A (en) * 2020-04-25 2020-08-07 武汉裕大华纺织有限公司 Qualitative inspection device and method for regenerated cellulose

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Publication number Priority date Publication date Assignee Title
CN2824837Y (en) * 2005-08-12 2006-10-11 成都仪器厂 Experimental apparatus for electrophysiological examination
CN103071246A (en) * 2013-02-19 2013-05-01 重庆大学 Repairing device and method for stimulating nerves by near infrared light
CN204065545U (en) * 2014-07-29 2014-12-31 杭州卓腾信息技术有限公司 Based on microscopical digital slices scanning laser focusing device
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CN204428628U (en) * 2015-01-06 2015-07-01 许秀梅 Electricity irritation acupuncture endocrine regulation instrument
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