CN110051450A - A kind of device and application method using pharmaceutical intervention prevention and treatment bovine tuberculosis - Google Patents
A kind of device and application method using pharmaceutical intervention prevention and treatment bovine tuberculosis Download PDFInfo
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- CN110051450A CN110051450A CN201910230804.3A CN201910230804A CN110051450A CN 110051450 A CN110051450 A CN 110051450A CN 201910230804 A CN201910230804 A CN 201910230804A CN 110051450 A CN110051450 A CN 110051450A
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- A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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Abstract
Device provided by the invention using pharmaceutical intervention prevention and treatment bovine tuberculosis, injection mechanism is set on fixed mechanism, injection mechanism includes syringe, restriction plate, driving motor, Return spring and injection spring, syringe is equipped with inside injection mechanism, syringe two sides are equipped with Return spring, connection in the middle part of Return spring one end and injection mechanism, Return spring other end is connected with restriction plate, syringe tail portion is equipped with guide rail, driving motor output end sets screw rod, screw rod is equipped with sliding block, sliding block one end is arranged in guide rail, push rod is equipped in syringe, push rod tail portion is equipped with injection spring and gag lever post, injection spring other end is connected with guide rail.The present invention, which uses, makes it possible that pharmaceutical intervention scale field is intensive, perlsuchts of high-density breeding field cows, and calf, the ratio of a course for the treatment of skin difference reduction is 47%；One course for the treatment of of young ox has 76.7% positive ox-hide difference to reduce；There is 42% positive ox-hide difference to reduce after one course for the treatment of of Grown cow, effect is obvious.
Description
Technical field
The invention belongs to herding quarantine fields, and in particular to the prevention and treatment quarantine device of perlsucht and use.
Background technique
Bovine tuberculosis is that a kind of infectious diseases common to human beings and animals, mycobacterium tuberculosis as caused by mycobacterium tuberculosis divide people
3 kinds of type, ox type and fowl type serotypes, wherein ox type can be infected mutually with human-like, and bacillus tuberculosis bovis passes through ox in order to prevent
Milk, beef, bovine respiratory, excrement etc. are transmitted to the mankind, and the tuberculosis that milk cow is controlled from source is extremely important.
Currently, the means of prevention to bovine tuberculosis mainly every year quarantines to bovine tuberculosis, it is right according to country
The prevention and treatment code requirement of bovine tuberculosis, carries out secondary quarantine to milk cow every year, and the method for quarantine is intradermal allergy test
The positive ox (skin depth difference >=4mm) of (abbreviation PPD test), detection is slaughtered (harmless treatment), suspicious ox (4mm > skin depth
Difference >=2mm) isolation.
Intradermal allergy test (abbreviation PPD test) be the intradermal metamorphosis that is carried out with mycobacterium bovis PPD instead
Answer, although this test method there are not perfect property (will appear false positive and false negative), the quarantine of perlsucht as defined in China
Method is animal diagnosis of tuberculosis technology (GB/T 18645-2002) and diagnosing bovine tuberculosis vitro detection interferon method (GB/
T 32945-2016), but since the cheap expense of PPD test reagent is low, it is easy to carry out, therefore be the milk cow that cattle farm generallys use
Tuberculosis surveillance method.By the effect test to positive ox pharmaceutical intervention, it is poor that PPD monitoring shows different degrees of skin
Variation, illustrates that drug has antibacterial and bactericidal effect to tubercle bacillus in Contents in Cows, to have similarly to compromised ox, suspicious ox
Effect.
Bovine tuberculosis increases in the positive rate of high density intensive cattle farm quarantine in recent years, the disease further through respiratory tract,
Excrement, milk etc. are propagated, and spread speed is fast, route of transmission is complicated, and people and animals once infect, it may appear that cough, is had loose bowels at syntexis, milk
The symptoms such as the ox output of milk declines, and produced calf survival rate is low.
Streptomysin is the specific medicament of anti-mycobacterium tuberculosis, belongs to aminoglycoside alkali compounds, it and tubercle bacillus thallus
Ribonucleoprotein body combines, and plays interference tubercle bacillus albumen synthesis, to kill or inhibit the life of tubercle bacillus
It is long.By intramuscular injection, the peak value of the drug concentration in blood occurs in 0.5-2h, as long as dosage is suitable, inhibits in blood
Easy to use as long as the effective concentration of growth of bacillus tubercle can keep 12h, Small side effects, allergic reaction is small, but in order to prevent
It influences foetus health and reduction medicine is residual, calver, cow in milk disabling.Dexamethasone (hormone) has anti-inflammatory, antiallergy, antitoxin work
With.Anti-inflammatory effect, which mainly mitigates ox, prevents reaction of the tissue to inflammation, inhibits inflammatory cell in the aggregation of inflammation part, and press down
Phagocytosis processed.It is shared in recent years with antibiotic, is mainly used for treating the disease or severe allergy of serious acute bacterial infection
Reaction, oncotherapy etc..
Generally speaking, 1. existing perlsucht epidemic prevention has the drawback that with intradermal allergy (PPD test) quarantine
Method has error, false positive and false negative easily occurs: false positive occurs and healthy ox is caused to be killed by mistake, cause economic loss, occur
False negative can cause infected cattle or morbidity ox leakage to kill, and cause to infect healthy ox.2. increasingly due to tuberculosis infection rate in recent years
Height, only by quarantining-slaughtering the prevalence of uncontrollable bovine tuberculosis.Secondly as infection rate is high, the positive ox of detection
More, economic loss is big, and it is big to slaughter difficulty.3. lacking precautionary measures to inferior health ox or the milk cow being on the hazard, to be allowed to send out
Exhibition is positive ox, causes milk cows that cannot thoroughly purify for a long time.4. only with a kind of this method to cause the more to quarantine the more more, sense
The trend of dye rate sustainable growth.
Summary of the invention
There is error for the method for the test quarantine of PPD in the prior art, only by quarantining-slaughtering uncontrollable milk cow knot
The prevalence of core disease, slaughters that difficulty is big, lacks precautionary measures to inferior health ox or the milk cow being on the hazard, to be allowed to development as sun
Property ox, the technical issues of causing milk cows that cannot thoroughly purify for a long time prevented and treated applicant provide a kind of using pharmaceutical intervention
The device and application method of bovine tuberculosis should not violate the prevention and treatment specification that country works out bovine tuberculosis, i.e., annual right
Milk cow carries out secondary quarantine, slaughters to the positive ox quarantined out, on this basis to compromised ox, suspicious ox, inferior health
Ox carries out pharmaceutical intervention.Using the intervention effect of drug, the propagation of bovine tuberculosis is controlled, the infection rate of milk cows is reduced, makes
Cows are further purified, and are difficult to when reaching control human world purpose lungy from source, and solving pharmaceutical intervention
The problem of application, it is no longer necessary to grab ox intramuscular injection one by one daily, greatly reduce manpower, so that pharmaceutical intervention scheme obtains
Effectively to use, there is wide applicability in agriculture and animal husbandry cultivation field.
In order to achieve the above objectives, a kind of device using pharmaceutical intervention prevention and treatment bovine tuberculosis, comprising injection mechanism and admittedly
Determine mechanism, injection mechanism is set on fixed mechanism, injection mechanism includes syringe, restriction plate, driving motor, Return spring and injection
Spring, injection mechanism inside are equipped with syringe, and syringe two sides are equipped with Return spring, connect in the middle part of Return spring one end and injection mechanism
It connects, Return spring other end is connected with restriction plate, and syringe tail portion is equipped with guide rail, and driving motor output end sets screw rod, on screw rod
Equipped with sliding block, sliding block one end is arranged in guide rail, and push rod is equipped in syringe, and push rod tail portion is equipped with injection spring and gag lever post, note
Projectile spring other end is connected with guide rail.
In the present invention, injection mechanism is equipped with several groups, and syringe front end is equipped with syringe needle.
In the present invention, Return spring setting is equipped with scale, is equipped between injection spring and push rod in syringe two sides, push rod
Stop collar.
In the present invention, injection mechanism bottom is equipped with rubber pad, and syringe needle is located at rubber pad top.
In the present invention, gag lever post is in the shape of the letter V, and gag lever post passes through stop collar both ends and stretches out syringe two sides.
In the present invention, restriction plate is equipped with through-hole, and through-hole and syringe are adapted setting, and gag lever post width is greater than in restriction plate
Through-hole, gag lever post use duroplasts.
In the present invention, fixed mechanism is equipped with oblique pull band, and oblique pull band other end is equipped with belly band.
In the present invention, battery is equipped in injection mechanism, battery is equipped with relay, and battery and relay are electrically connected, after
Electric appliance and driving motor are electrically connected.
In the present invention, sliding block one end is equipped with orientation block, and orientation block is arranged in guide rail 15.
The present invention provides the application methods of the device using pharmaceutical intervention prevention and treatment bovine tuberculosis, include the following steps:
(1) course for the treatment of and number the setting syringe quantity injected as needed, are arranged the interval time of relay between injection
Every the time；
(2) medicament of matched doses is sucked in syringe according to the age of ox；
(3) fixed mechanism is tied up into the scapular region in ox, belly band is tied up on tripe, will be bound between belly band and fixed mechanism tiltedly
Drawstring；
(4) it opens relay the movable slider movement of driving motor rotation band, sliding block in injection to depress guide rail, syringe needle passes through
Rubber pad is pierced into ox muscle, and gag lever post is broken off when passing through restriction plate, and injection spring pop-up pushes push rod to inject drug, injection
After, relay is again started up, and guide rail moves up syringe and extracted by Return spring, after syringe needle income to rubber pad, crosses a note
After penetrating the period, relay is again turned on the second needle of injection.
In application method of the present invention using the device of pharmaceutical intervention prevention and treatment bovine tuberculosis, driving motor retracts sliding block
After having injected a course for the treatment of, driving motor is resetted, again the Sucked medicine in syringe, fixed mechanism is tied up in other ox body
On.
The technical solution of pharmaceutical intervention
(1) calf: the age 0~1 years old.
1. the negative ox (inferior health, compromised) that PPD test is quarantined out, 2,000,000 units of streptomysin/day, intramuscular injection 1
Times/day, continuous 5~7 days are 1 course for the treatment of.
2. PPD tests the skin depth difference≤2mm ox quarantined out, 3,000,000 units of streptomysin/day, connect by 1 times/day of intramuscular injection
Continuous 5~7 days are 1 course for the treatment of, amount to 2 courses for the treatment of, interphase was every 3~5 days.
The ox of skin difference > 2mm 3. PPD test is quarantined out, 4,000,000 units of streptomysin/day, dexamethasone 10mL/ days, muscle
1 times/day of injection, 5~7 days are 1 course for the treatment of, and continuous 2 courses for the treatment of, interphase was every 3~5 days.
(2) young ox: the age 1~2 years old
1. the negative ox (inferior health, compromised) that PPD test is quarantined out, 3,000,000 units of streptomysin/day intramuscular injection, continuous 5~
7 days.
2. skin depth difference≤2mm that PPD test is quarantined out, 4,000,000 units of streptomysin/day intramuscular injection, continuous 5~7 days, 1~2
The course for the treatment of.
3. PPD tests the skin depth difference >=2mm ox quarantined out, 6,000,000 units of streptomysin/day intramuscular injection, dexamethasone 20mL/
It, intramuscular injection, every natural gift 2 times, two minor ticks 12 hours, 2 courses for the treatment of, each course for the treatment of 5~7 days.
(3) Grown cow: greater than 2 year old
1. the negative ox (inferior health, compromised) that PPD test is quarantined out, 5,000,000 units of streptomysin/day intramuscular injection, daily 1
It is secondary, continuous 5~7 days.
2. PPD tests the skin depth difference≤2mm to quarantine out, 7,000,000 units of streptomysin/day intramuscular injection, 2 times a day, 1~2 is treated
Journey, each course for the treatment of 5~7 days.
3. skin depth difference >=2mm ox that PPD test is quarantined out, 9,000,000 units of streptomysin/day, dexamethasone 20mL/ days,
Intramuscular injection, every natural gift 2 times, two minor ticks 12 hours, 2 courses for the treatment of, each course for the treatment of 5~7 days.
Compared with prior art, the present invention has the advantage that:
1, the 1st PPD tests the positive calf for the skin difference > 4mm that quarantines out, after apparatus of the present invention use, the 2nd PPD examination
It tests compared with the 1st time, negative conversion rate 0, the ratio of skin difference reduction is 47%, and the ratio that skin difference increases is 43%；3rd PPD examination
Result is tested compared with the 1st time, negative conversion rate is 35.3% (skin difference≤2mm), and the ratio that skin difference reduces is 88.2%, what skin difference increased
Ratio is 11.8%, and control efficiency is particularly evident；1st PPD tests the young ox of the positive for the skin difference > 4mm that quarantines out, in this hair
After bright device use, after the continuous stimulation in 10 days of a course for the treatment of streptomysin, the 2nd PPD test result and the 1st ratio
Compared with thering is 76.7% positive ox-hide difference to reduce, there is 23.3% positive ox-hide difference to increase, control efficiency is obvious；1st PPD examination
The positive Grown cow for testing the skin difference > 4mm that quarantines out passes through a course for the treatment of streptomysin continuous 10 days after apparatus of the present invention use
After stimulation, the 2nd PPD test result has 42% positive ox-hide difference to reduce, there is 57.1% positive ox compared with the 1st time
Skin difference increases, and effect is obvious.
2, the device of the invention and application method make that pharmaceutical intervention scale field is intensive, oxen of high-density breeding field cows
Tuberculosis is possibly realized, and is solved single ox and is arrested injection daily and needs to expend a large amount of manpower and material resources, and is easy to happen something lost
Existing drug utilization has been arrived in perlsucht prevention, has been improved with intradermal allergy (PPD test) by the case where leakage injection
Detection has the control efficiency of the inferior health ox in the cows of positive ox or suspicious ox.
Detailed description of the invention
Fig. 1 is the apparatus structure schematic diagram that the present invention prevents and treats bovine tuberculosis using pharmaceutical intervention.
Fig. 2 is syringe cylinder structure schematic diagram one of the present invention.
Fig. 3 is syringe cylinder structure schematic diagram two of the present invention.
Fig. 4 is syringe cylinder structure schematic diagram three of the present invention.
Fig. 5 is fixed mechanism structural schematic diagram of the present invention.
In Fig. 1-5,1- fixed mechanism, 2- injection mechanism, 3- oblique pull band, 4- belly band, 5- battery, 6- relay, 7- syringe,
8- syringe needle, 9- Return spring, 10- restriction plate, 11- driving motor, 12- sliding block, 13- orient block, 14- screw rod, 15- guide rail, 16-
Injection spring, 17- stop collar, 18- push rod, 19- gag lever post.
Specific embodiment
1 to attached drawing 5 and embodiment with reference to the accompanying drawing, and specific embodiments of the present invention will be described in further detail,
But apparatus of the present invention are not limited to following embodiments.
In the present invention, oblique pull band, belly band 4, battery 5, relay 6, syringe 7, syringe needle 8, Return spring in following embodiments
9, restriction plate 10, driving motor 11, sliding block 12, orientation block 13, screw rod 14, guide rail 15, injection spring 16, stop collar 17, push rod
18, gag lever post 19 belongs to those skilled in the art and buys selection or customization by market, belongs to common device, does not limit
Implementation of the invention.
Embodiment one: the present invention prevents and treats the device of bovine tuberculosis using pharmaceutical intervention
A kind of device using pharmaceutical intervention prevention and treatment bovine tuberculosis provided by the invention, comprising injection mechanism 2 and is fixed
Mechanism 1, injection mechanism 2 is arranged on fixed mechanism 1, and injection mechanism 2 includes syringe 7, restriction plate 10, driving motor 11, bullet of pulling back
Spring 9 and injection spring 16, are equipped with syringe 7 inside injection mechanism 2, and 7 two sides of syringe are equipped with Return spring 9,9 one end of Return spring and
It is connected in the middle part of injection mechanism 2,9 other end of Return spring and restriction plate 10 connect, and 7 tail portion of syringe is equipped with guide rail 15, driving electricity
11 output end of machine sets screw rod 14, and screw rod 14 is equipped with sliding block 12, and 12 one end of sliding block is arranged in guide rail 15, is equipped with and pushes away in syringe 7
Bar 18,18 tail portion of push rod are equipped with injection spring 16 and gag lever post 19, and 16 other end of injection spring and guide rail 15 connect.
In the present invention, injection mechanism 2 is equipped with several groups, and 7 front end of syringe is equipped with syringe needle 8.
In the present invention, the setting of Return spring 9 is equipped with scale, injection spring 16 and push rod 18 in 7 two sides of syringe, push rod 18
Between be equipped with stop collar 17.
In the present invention, 2 bottom of injection mechanism is equipped with rubber pad, and syringe needle 8 is located at rubber pad top.
In the present invention, gag lever post 19 is in the shape of the letter V, and gag lever post 19 passes through 17 both ends of stop collar and stretches out 7 two sides of syringe.
In the present invention, restriction plate 10 is equipped with through-hole, and through-hole and syringe 7 are adapted setting, and 19 width of gag lever post is greater than limit
Through-hole in making sheet 10, gag lever post 19 use duroplasts.It is broken off when gag lever post 19 is by restriction plate 10, injection spring 16 pops up
Push rod 18 is released and squeezes out drug completion injection.
In the present invention, fixed mechanism 1 is equipped with oblique pull band 3, and 3 other end of oblique pull band is equipped with belly band 4.
In the present invention, battery 5 is equipped in injection mechanism 2, battery 5 is equipped with relay 6, and battery 5 and relay 6 electrically connect
It connects, relay 6 and driving motor 11 are electrically connected.
In the present invention, 12 one end of sliding block is equipped with orientation block 13, and orientation block 13 is arranged in guide rail 15.
Embodiment two: the application method of the device of pharmaceutical intervention prevention and treatment bovine tuberculosis is utilized
The present invention provides the application methods of the device using pharmaceutical intervention prevention and treatment bovine tuberculosis, include the following steps:
(1) course for the treatment of and number the setting syringe quantity injected as needed, the interval time of setting relay 6 are between injecting
Every the time；
(2) medicament of matched doses is sucked in syringe 7 according to the age of ox；
(3) fixed mechanism 1 is tied up into the scapular region in ox, belly band 4 is tied up on tripe, will be tied up between belly band 4 and fixed mechanism 1
Upper oblique pull band 3；
(4) relay 6 movement of movable slider 12 of the rotation of driving motor 11 band, sliding block 12 in injection is opened to press guide rail 15
Under, syringe needle 8 passes through rubber pad and is pierced into ox muscle, and by being broken off when restriction plate 10, the pop-up of injection spring 16 pushes away gag lever post 19
Dynamic push rod 18 injects drug, and after injection, relay 6 is again started up, and guide rail 15 moves up syringe 7 and extracted by Return spring 9, needle
After first 8 income to rubber pad, after crossing an injection cycle, relay 6 is again turned on the second needle of injection.
In application method of the present invention using the device of pharmaceutical intervention prevention and treatment bovine tuberculosis, driving motor 11 is by sliding block 12
It retracts after having injected a course for the treatment of, driving motor 11 is resetted, the Sucked medicine in syringe 7, fixed mechanism 1 is tied up other again
Ox with.
Embodiment three: the method for pharmaceutical intervention prevention and treatment bovine tuberculosis is utilized
1. the object of pharmaceutical intervention prevention and treatment
1. regional or intradermal allergy (PPD test) high scale field of recall rate of TB endemic is intensive, highly dense
Spend the cows of farm.
2. there is the inferior health ox in the cows of positive ox or suspicious ox with intradermal allergy (PPD test) detection.
3. being in cows or the areal region in the area or region of TB endemic positive ox of quarantining to exceed
The cows of state control standard (> 3%) or individual.
4. intradermal allergy is the positive, but does not show the segregate individual ox of symptom.
The object of pharmaceutical intervention does not include cow in milk, pregnancy ox.
2. the ancillary measure of pharmaceutical intervention prevention and treatment
1. must first slaughter to the positive ox that PPD quarantines out, suspicious ox must first be isolated.
2. reinforcing the feeding management of milk cow, stocking density is reduced, high-quality complete feed is fed, clears up fecaluria in time, kept
Steady temperature, humidity in giving up are reinforced giving up interior ventilation, enhance milk cow constitution.
3. reduce it is various stress, especially it is xeothermic emergency and it is clammy stress and Other diseases stress.
4. reinforcing environment disinfected.
5. feeding pasturising milk to calf.
6. stringent quarantine quarantine measures must be carried out before mixed group
3. the technical solution of pharmaceutical intervention
(1) calf: the age 0~1 years old.
1. the negative ox (inferior health, compromised) that PPD test is quarantined out, 2,000,000 units of streptomysin/day, intramuscular injection 1
Times/day, continuous 5~7 days are 1 course for the treatment of.
2. PPD tests the skin depth difference≤2mm ox quarantined out, 3,000,000 units of streptomysin/day, connect by 1 times/day of intramuscular injection
Continuous 5~7 days are 1 course for the treatment of, amount to 2 courses for the treatment of, interphase was every 3~5 days.
The ox of skin difference > 2mm 3. PPD test is quarantined out, 4,000,000 units of streptomysin/day, dexamethasone 10mL/ days, muscle
1 times/day of injection, 5~7 days are 1 course for the treatment of, and continuous 2 courses for the treatment of, interphase was every 3~5 days.
(2) young ox: the age 1~2 years old
1. the negative ox (inferior health, compromised) that PPD test is quarantined out, 3,000,000 units of streptomysin/day intramuscular injection, continuous 5~
7 days.
2. skin depth difference≤2mm that PPD test is quarantined out, 4,000,000 units of streptomysin/day intramuscular injection, continuous 5~7 days, 1~2
The course for the treatment of.
3. PPD tests the skin depth difference >=2mm ox quarantined out, 6,000,000 units of streptomysin/day intramuscular injection, dexamethasone 20mL/
It, intramuscular injection, every natural gift 2 times, two minor ticks 12 hours, 2 courses for the treatment of, each course for the treatment of 5~7 days.
(3) Grown cow: greater than 2 year old
1. the negative ox (inferior health, compromised) that PPD test is quarantined out, 5,000,000 units of streptomysin/day intramuscular injection, daily 1
It is secondary, continuous 5~7 days.
2. PPD tests the skin depth difference≤2mm to quarantine out, 7,000,000 units of streptomysin/day intramuscular injection, 2 times a day, 1~2 is treated
Journey, each course for the treatment of 5~7 days.
3. skin depth difference >=2mm ox that PPD test is quarantined out, 9,000,000 units of streptomysin/day, dexamethasone 20mL/ days,
Intramuscular injection, every natural gift 2 times, two minor ticks 12 hours, 2 courses for the treatment of, each course for the treatment of 5~7 days.
The daily dosage reference table of 1 milk cow streptomysin of table
Calf (0~1 years old): intramuscular injection 2,000,000 units of streptomysin/head for animals after the 1st PPD is tested 20 days, continuously
Ten days.After being discontinued 30 days, the 2nd PPD test, it is poor to measure its skin, analyzes the variation of its skin difference.After the 2nd PPD is tested 15 days, the 2nd
4,000,000 units of secondary intramuscular injection streptomysin/head, while injecting dexamethasone 10ml/ head.Two courses for the treatment of, each course for the treatment of 5 days, not
The medicine phase 5 days.10 days after two courses for the treatment of, it is poor to survey its skin for the 3rd PPD test.
2 calf of table, 3 PPD test results (unit: ㎜)
The 2nd PPD test of calf is compared with the 1st time, and negative conversion rate 0, the ratio of skin difference reduction is 47%, what skin difference increased
Ratio is 43%；For 3rd PPD test result compared with the 1st time, negative conversion rate is 35.3% (skin difference≤2mm), the ratio that skin difference reduces
Example is 88.2%, and the ratio that skin difference increases is 11.8%, and control efficiency is particularly evident.
Young ox (1~2 years old): after the 1st PPD is tested 20 days, intramuscular injection 4,000,000 units of streptomysin/head for animals, even
10 days continuous, the 2nd PPD test, it is poor to survey its skin after being discontinued 30 days.
The young 2 PPD test results of ox (unit: ㎜) of table 3
Grown cow (>=2 years old): after the 1st PPD is tested 20 days, intramuscular injection 4,000,000 units of streptomysin/head for animals, even
10 days continuous, after being discontinued 30 days, it is poor to survey its skin for the 2nd PPD test.
4 Grown cow of table, 2 PPD test results (unit: ㎜)
After Grown cow passes through the continuous stimulation in 10 days of a course for the treatment of streptomysin, the 2nd PPD test result and the 1st ratio
Compared with thering is 42% positive ox-hide difference to reduce, there is 57.1% positive ox-hide difference to increase, effect is obvious.
Control group: it is made of the positive calf, young ox, Grown cow quarantined out, is rechecked after 42d is isolated, it is poor to survey its skin.
5 control group of table, 2 PPD test result statistics (unit: ㎜)
Control group has 1 ox to turn out cloudy (2 ㎜ of skin difference <) by reinspection, has 4 (18%) skin differences to reduce, has 77% ox-hide poor
Increase, does not improve.
Example IV: the present invention utilizes performance analysis after the device of pharmaceutical intervention prevention and treatment bovine tuberculosis
Using apparatus of the present invention and completely manually according to the daily pharmaceutical intervention of pharmaceutical intervention scheme progress, every batch of ox knot is counted
Core medicine intervenes artificial and time cost.
6 apparatus of the present invention of table and artificial intramuscular injection performance analysis
| Grouping | What is needed is artificial | The one treatment course costs time of every ox |
| Apparatus of the present invention | 3 | 7h |
| Artificial control group | 2 | 1h |
It can be seen from above-mentioned test data using efficiently solved after apparatus of the present invention utilize pharmaceutical intervention prevent and treat milk cow
The problem of tuberculosis heavy workload, and the case where being not in omission after ox is worn one by one, until one course for the treatment of note of each ox
It shoots away and unloads from new replacement syringe needle and the other ox of drug injection, do not needing people to spend the problem of grabbing ox and injection of exering great efforts.
As described above, the present invention can be realized preferably, the above embodiments are only to preferred implementation side of the invention
Formula is described, and is not intended to limit the scope of the present invention, and without departing from the spirit of the design of the present invention, this field is general
The various changes and improvements that logical technical staff makes technical solution of the present invention, should all fall into present invention determine that protection scope
It is interior.
Claims (10)
1. a kind of device using pharmaceutical intervention prevention and treatment bovine tuberculosis, includes injection mechanism and fixed mechanism, which is characterized in that
Injection mechanism is set on the fixed mechanism, and injection mechanism includes syringe, restriction plate, driving motor, Return spring and injection bomb
Spring, injection mechanism inside are equipped with syringe, and syringe two sides are equipped with Return spring, connect in the middle part of Return spring one end and injection mechanism,
Return spring other end is connected with restriction plate, and syringe tail portion is equipped with guide rail, and driving motor output end sets screw rod, and screw rod is equipped with
Sliding block, sliding block one end are arranged in guide rail, and push rod is equipped in syringe, and push rod tail portion is equipped with injection spring and gag lever post, injection bomb
Spring other end is connected with guide rail.
2. the device according to claim 1 using pharmaceutical intervention prevention and treatment bovine tuberculosis, it is characterised in that: the injection
Mechanism is equipped with several groups, and syringe front end is equipped with syringe needle.
3. the device according to claim 1 using pharmaceutical intervention prevention and treatment bovine tuberculosis, it is characterised in that: described to pull back
Spring setting is equipped with scale in syringe two sides, push rod, and stop collar is equipped between injection spring and push rod.
4. the device according to claim 1 using pharmaceutical intervention prevention and treatment bovine tuberculosis, it is characterised in that: the injection
Actuator base is equipped with rubber pad, and syringe needle is located at rubber pad top.
5. the device according to claim 1 using pharmaceutical intervention prevention and treatment bovine tuberculosis, it is characterised in that: the limit
Bar is in the shape of the letter V, and gag lever post passes through stop collar both ends and stretches out syringe two sides.
6. the device according to claim 1 using pharmaceutical intervention prevention and treatment bovine tuberculosis, it is characterised in that: the limitation
Plate is equipped with through-hole, and through-hole and syringe are adapted setting, and gag lever post width is greater than through-hole in restriction plate, and gag lever post uses hard plastic
Material.
7. the device according to claim 1 using pharmaceutical intervention prevention and treatment bovine tuberculosis, it is characterised in that: the fixation
Mechanism is equipped with oblique pull band, and oblique pull band other end is equipped with belly band.
8. utilizing the device of pharmaceutical intervention prevention and treatment bovine tuberculosis as described in claim 1, which is characterized in that the injector
Battery is equipped in structure, battery is equipped with relay, and battery and relay are electrically connected, and relay and driving motor are electrically connected.
9. such as the application method of the described in any item devices using pharmaceutical intervention prevention and treatment bovine tuberculosis of claim 1-8,
It is characterized in that, the application method includes the following steps:
(1) course for the treatment of and number the setting syringe quantity injected as needed, when the interval time that relay is arranged is injection interval
Between；
(2) medicament of matched doses is sucked in syringe according to the age of ox；
(3) fixed mechanism is tied up into the scapular region in ox, belly band is tied up on tripe, and oblique pull will be bound between belly band and fixed mechanism
Band；
(4) it opens relay the movable slider movement of driving motor rotation band, sliding block in injection to depress guide rail, syringe needle passes through rubber
Pad is pierced into ox muscle, and gag lever post is broken off when passing through restriction plate, and injection spring pop-up pushes push rod to inject drug, and injection finishes
Afterwards, relay is again started up, and guide rail moves up syringe and extracted by Return spring, after syringe needle income to rubber pad, spends an injection week
After phase, relay is again turned on the second needle of injection.
10. device used in the device preparation method of bovine tuberculosis is prevented and treated using pharmaceutical intervention as claimed in claim 9
Application method, which is characterized in that the driving motor retracts sliding block injected a course for the treatment of after, driving motor is resetted, then
The secondary Sucked medicine in syringe, fixed mechanism is tied up with other ox.
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Cited By (2)
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| CN112076006A (en) * | 2020-08-17 | 2020-12-15 | 山东省动物疫病预防与控制中心 | Device for treating tuberculosis of dairy cow by drug intervention and using method |
| CN112137753A (en) * | 2020-08-17 | 2020-12-29 | 山东省动物疫病预防与控制中心 | Medicine prevention and control device for brucellosis in sheep |
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| CN110051450B (en) | 2021-08-20 |
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