CN110038080A - One kind is for treating cardiopathic Chinese patent drug and preparation method thereof - Google Patents
One kind is for treating cardiopathic Chinese patent drug and preparation method thereof Download PDFInfo
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Abstract
The present invention provides one kind for treating cardiopathic Chinese patent drug and preparation method thereof, the raw material of the Chinese patent drug includes Radix Astragali, Radix Codonopsis, Radix Notoginseng, cordyceps sinensis, pilose antler, dried human placenta, amber, glossy ganoderma powder, safflower, spina gleditsiae, leech, dragon's blood, big gun first pearl, centipede, the weight ratio of each raw material are as follows: 60 parts of Radix Astragali, 30 parts of Radix Codonopsis, 20 parts of Radix Notoginseng, 20 parts of cordyceps sinensis, 10 parts of pilose antler, 6 parts of dried human placenta, 6 parts of amber, 6 parts of glossy ganoderma powder, 3 parts of safflower, 3 parts of spina gleditsiae, 3 parts of leech, 3 parts of dragon's blood, 3 parts of big gun first pearl, 3 parts of centipede.It is provided by the invention a kind of for treating cardiopathic Chinese patent drug with warm kidney benefit essence, raw marrow bone strengthening, help board lung;It invigorates blood circulation treating stranguria, removing blood stasis and hemostasis, dredging collateral to stop pain, heart tonifying diuresis, the immune effect of reconstruction, and have preferable effect to heart disease, it has no toxic side effect;Show that cure rate reaches 93% by the clinical use of several patients, it is still effective to continue medication for obvious effective rate 5%, recurrence rate after healing 2%.
Description
Technical field
The invention belongs to Chinese drugs agentia formula technique fields, are related to a kind of for treating cardiopathic Chinese patent drug, the present invention
Further relate to the preparation method of this Chinese patent drug.
Background technique
Coronary atherosclerotic heart disease is that coronary artery occurs atherosclerotic lesion and causes blood vessel
Chamber stenosis or occlusion causes heart disease, commonly referred to as " coronary heart disease " caused by myocardial ischemia, anoxic or necrosis.But it is preced with
The range of heart trouble may further include more extensively that inflammation, embolism etc. lead to luminal stenosis or occlusion.The World Health Organization is by coronary heart disease
It is divided into 5 major class: silent ischemia (latent coronary heart disease), angina pectoris, myocardial infarction, ischemic heart failure (ischemic
Heart disease) and 5 kinds of Clinical types of sudden death.
For many years, western medical treatment coronary heart disease mainly has physiotherapy, i.e. heart pass and intravascular stent and western medicine.I.e.
Utilize the drug therapies such as Nitrates, beta-blocker, calcium channel blocker, anti-coagulants.Although chemicals effect is rapidly,
But side effect is larger in therapeutic process, as isosorbide dinitrate can cause headache, dizzy, reflex tachycardia and orthostatic hypotension
Deng.Beta-blocker such as inderal, atenolol etc. can cause or induce left heart insufficiency, serious tachycardia or conduction
Retardance, bronchoconstriction, central nervous system and gastrointestinal discomfort and withdrawal syndrome etc..Therefore, it is true to find a kind of curative effect
It cuts, the drug of few side effects is task and the direction of numerous medical personnels.
Summary of the invention
The purpose of the present invention is to provide one kind for treating cardiopathic Chinese patent drug, solves existing doctor trained in Western medicine operation, Western medicine
The problem of side effect is big, unsatisfactory curative effect.
Second object of the present invention is to provide the preparation method of above-mentioned Chinese patent drug.
For one kind for treating cardiopathic Chinese patent drug, the raw material of the Chinese patent drug includes Radix Astragali, Radix Codonopsis, Radix Notoginseng, cordyceps sinensis, deer
Young pilose antler, dried human placenta, amber, glossy ganoderma powder, safflower, spina gleditsiae, leech, dragon's blood, big gun first pearl, centipede, the weight ratio of each raw material are as follows:
60 parts of Radix Astragali, 30 parts of Radix Codonopsis, 20 parts of Radix Notoginseng, 20 parts of cordyceps sinensis, 10 parts of pilose antler, 6 parts of dried human placenta, 6 parts of amber, 6 parts of glossy ganoderma powder, safranine
Spend 3 parts, 3 parts of spina gleditsiae, 3 parts of leech, 3 parts of dragon's blood, 3 parts of big gun first pearl, 3 parts of centipede.
It is above-mentioned for treating cardiopathic Chinese patent drug the preparation method comprises the following steps: above-mentioned each medicinal material is dried, remove impurity, crush
Afterwards, 120 meshes are crossed, the lower drug of sieve is taken, is uniformly mixed and Chinese patent drug is made.
Preferably, instant particles as Chinese medicine, tablet, water-bindered pill agent or capsule is made in above-mentioned uniformly mixed drug.
The effect of above-mentioned each raw material, is as follows:
Radix Astragali: invigorating qi for strengthening superficies, diuresis, pus draining and toxin expelling, myogenic sore cure mainly shortness of breath and palpitation, burnout, out of strength, spontaneous perspiration, night sweat, body
Impractical swollen, chronic nephritis, ulcer is difficult to burst.Modern medical studies have confirmed that Radix Astragali has diuretic antihypertensive, anti-inflammatory analgesic, heart tonifying, antioxygen
Free radical generates and improves the multiple pharmacological effects such as body's immunity, can act on body from many aspects, improves cardiovascular, brain
The relevant blood vessels venereal disease such as blood vessel, diabetes, nephrosis becomes the functions such as haemodynamics and the vascular endothelial cell of patient.
Radix Codonopsis: reducing blood lipid, the blood that disappears is stifled, QI invigorating, invigorating the spleen.
Radix Notoginseng: dredging collateral to stop pain, removing blood stasis and hemostasis.
Cordyceps sinensis: receiving gas Dingchuan, corrects heart failure, reinforces vital energy, and improves immune.
Pilose antler: warming and invigorating kidney Yang, benefiting essence-blood strengthening the bones and muscles can make increased heart rate, increase stroke volume, and angioplerosis blood pressure rises,
Heart sound is strong, and hat blood flow increases.
Dried human placenta: mending greatly congenital, supplement qi and blood, and enhancing human immunity promotes regeneration to develop.
Amber: centering hair mind, anti-arrhythmia and Radix Codonopsis Radix Notoginseng share, become silted up and hinder to qi and blood, and chest low costalgia has special effect.
Glossy ganoderma powder: qi-restoratives righting, antitoxic heart-soothing and sedative, anti-aging is anti-oxidant, strengthening by means of tonics function.
Safflower: activate blood circulation and disperse blood clots, removing pattogenic heat from the blood and toxic material from the body, resolving stagnation for tranquilization the effect of.
Spina gleditsiae: pus draining and toxin expelling, the carbuncle that disappears of invigorating blood circulation search wind desinsection.
Leech: hirudin is the special efficacy element of antithrombase, has the function of the anticoagulant thrombus of anti-bolt, can reduce
Whole blood viscosity and fiber protein content increase the effect of myocardial alimentary blood flow.
Dragon's blood: blood-activating analgetic can significantly inhibit platelet aggregation, prevent thrombosis, anti-myocardial anoxia arrhythmia cordis
Effect.
Big gun first pearl: there are the names such as first pearl, stir-baked SQUAMA MANITIS.Energy blood circulation promoting and dispersing pathogen accumulation, anti-stain in solid, carbuncle swells, scrofula etc..
Centipede: expelling wind and relieving convulsion is removed obstruction in channels to relieve pain, and fresh poison dissipating bind there is decompression to resist myocardial ischemia, anti-oxidation function.
The invention has the following beneficial effects:
(1) provided by the invention a kind of for treating cardiopathic Chinese patent drug, there is warm kidney to mend essence, raw marrow bone strengthening, help board lung;
It invigorates blood circulation treating stranguria, removing blood stasis and hemostasis, dredging collateral to stop pain, heart tonifying diuresis, the immune effect of reconstruction;A variety of heart diseases are had a better effect,
It is the effect side by long-term clinical application.
(2) provided by the invention a kind of for treating cardiopathic Chinese patent drug, it is formulated in strict accordance with eighteen imcompatible pairs ten
Compatibility is avoided in nine fears and medication, has been evaded between drug opposite, mutual restraint between two drugs and medication taboo, has been had no toxic side effect, no nocuousness at
Point;Drug effect is complementary, and curative for effect, preparation method is simple, is suitble to modern's dosing requirements, is the successful wound of Chinese materia medica preparation remodeling
Newly.
(3) provided by the invention a kind of for treating cardiopathic Chinese patent drug, which has a variety of heart diseases preferable
Therapeutic effect;Show that cure rate reaches 93% by the clinical use of the several patients of logarithm, obvious effective rate 5%, recurrence rate after healing 2%,
Therapeutic effect increases after patients with recurrent continues medication.
Specific embodiment
Below with reference to embodiment, specific embodiments of the present invention will be described in further detail.
Embodiment 1
For one kind for treating cardiopathic Chinese patent drug, the raw material of the Chinese patent drug includes Radix Astragali, Radix Codonopsis, Radix Notoginseng, cordyceps sinensis, pilose antler, purple
River vehicle, amber, glossy ganoderma powder, safflower, spina gleditsiae, leech, dragon's blood, big gun first pearl, centipede, the quality of above-mentioned each component are as follows: Radix Astragali
60g, Radix Codonopsis 30g, Radix Notoginseng 20g, cordyceps sinensis 20g, pilose antler 10g, dried human placenta 6g, amber 6g, glossy ganoderma powder 6g, safflower 3g, spina gleditsiae 3g,
Leech 3g, dragon's blood 3g, big gun first pearl 3g, centipede 3g.
The Chinese patent drug the preparation method comprises the following steps: above-mentioned each medicinal material is dried, remove impurity, be ground into smalls, cross 120 meshes,
The lower drug of sieve is taken, is uniformly mixed and Chinese patent drug is made.
180g hybrid medicine (1 month dosage) is weighed, medicine smalls is fitted into No. 0 capsule, capsule, about 450 is made
Grain, every quality are 0.4g.
Instant particles as Chinese medicine, tablet or water-bindered pill agent can also be made in above-mentioned hybrid medicine smalls.
The Chinese patent drug is suitable for taking with coronary heart disease, a variety of cardiopathic patients.
Instructions of taking and dosage: once a dose in the morning, afternoon and evening, and before meals or 1 hour after meal takes with warm water, each taking 5
(about 2g), takes 6g altogether daily.Medicining cycle is 100 days, then does doctor trained in Western medicine institute cardiac work up;(consolidation) amount of halving of dealing with problems arising from an accident clothes
Medicine, period are 3 months;Conditional patient, which can deal with problems arising from an accident, to take medicine 1 year, and every take one month has three days off.
Points for attention: duration of medication eats maror irritable food less.
The case of clinical efficacy:
Case 1: king XX, male, 65 years old.
First visit: it goes to a doctor at the beginning of 1 month 2019.Symptoms include: blood pressure 165/95mHg, 56 beats/min of heart rate, dimly red tongue, the tip of the tongue has
Petechia, arteries and veins is puckery late, and double the kidney pulse being deep are weak.Frequent repeated cold, cough is very;Uncomfortable in chest, shortness of breath, it is poor to sleep, out of strength tired out.Treatment needs
Tonifying Qi and blood, activating microcirculation and removing stasis medicinal.
Prescription: a month dose (180g, about 450) is given;It advises and often takes daily 6 grams (15), 5 tablets each time, divide 3 times
Clothes;It takes within 1 hour after meal;It even served 1-3 months.
Two examine: further consultation on the 5th in 2 months in 2019, and after medication one month, shortness of breath uncomfortable in chest is held every time by breaking out 4-5 times weekly originally
It renews a contract 5 minutes, breaks out 1-2 times weekly now, last for several seconds clock;It is energetic at present, it walks 1 hour or slight labour is not tired
Labor, shortness of breath phenomenon uncomfortable in chest disappear, and insomnia improves, and can sleep every night six or seven hour.
Three examine: continuing medication to April and make doctor trained in Western medicine inspection on 3rd, all symptoms disappear, originally the blood vessel of the stasis of blood stifled 70%, the inspection result stasis of blood
25%;Continuation is advised to take medicine according to former dosage to recovery from illness.
The four methods of diagnosis: 2019 April 20 days.Recovery from illness, advises the amount of halving to continue to take medicine, deals with problems arising from an accident and eradicate it.
Case 2: king XX, male, 75 years old.
First visit: medical on November 3rd, 2018.Double the kidney pulse being deep are weak, and right close is floated greatly, very little heavy;Thick greasy tongue coating;It coughs very, gas
Short, uncomfortable in chest, palpitaition happens occasionally daily, and several minutes of the duration, it is poor to sleep, and has no appetite, has a poor appetite;It is grey on the face, it is unglazed
Pool.Treatment needs activating microcirculation and removing stasis medicinal, tonifies the liver and kidney;
Prescription: giving the amount of mixed powder (No. 0 capsule) one month 180g, and about 450;Every natural gift 3 times clothes, 5 tablets each time (No. 0 glue
Capsule, every 0.4g), it takes within 1 hour before meals, often takes daily 6g, about 15.
Two examine: on November 18th, 2018, and after two weeks of taking medicine, perfume of having a meal, appetite increases, and legs and feet are strong;Gas uncomfortable in chest
Short improvement, cough are cured, and palpitaition occurs 1-2 times weekly, time only last for several seconds clock;Of pink and healthy-looking, tongue fur is thinning, and sleep changes
It is kind, it becomes quite a different person.It advises and continues to take medicine, the clinic that comes in time at present takes medicine, deals with problems arising from an accident and consolidates it.
Three examine: on 2 6th, 2019, recovery from illness.The amount of halving is advised to continue medication to eradicate.
It is provided by the invention a kind of for treating cardiopathic Chinese patent drug, pass through the clinical use table to tens of patients
Bright, cure rate reaches 93%, and obvious effective rate 5%, recurrence rate after healing 2%, therapeutic effect increases after patients with recurrent continues medication.
It is provided by the invention a kind of for treating cardiopathic Chinese patent drug, there is warm kidney to mend essence, raw marrow bone strengthening, help board
Lung;It invigorates blood circulation treating stranguria, removing blood stasis and hemostasis, dredging collateral to stop pain, heart tonifying diuresis, the immune effect of reconstruction;And has to heart disease and preferably control
Therapeutic effect is the effect side by long-term clinical application.The formula is avoided in strict accordance with eighteen imcompatible pairs nineteen counteraction and medication
Compatibility has evaded opposite, mutual restraint between two drugs and medication taboo between drug, has had no toxic side effect, no harmful components;Drug effect is complementary, curative effect
Definitely, preparation method is simple, is suitble to modern's dosing requirements, is the successful innovation of Chinese materia medica preparation remodeling.
Claims (3)
1. one kind is for treating cardiopathic Chinese patent drug, it is characterised in that: the raw material of the Chinese patent drug include Radix Astragali, Radix Codonopsis, Radix Notoginseng,
Cordyceps sinensis, pilose antler, dried human placenta, amber, glossy ganoderma powder, safflower, spina gleditsiae, leech, dragon's blood, big gun first pearl, centipede, the weight of each raw material
Measure ratio are as follows: 60 parts of Radix Astragali, 30 parts of Radix Codonopsis, 20 parts of Radix Notoginseng, 20 parts of cordyceps sinensis, 10 parts of pilose antler, 6 parts of dried human placenta, 6 parts of amber, glossy ganoderma powder 6
Part, 3 parts of safflower, 3 parts of spina gleditsiae, 3 parts of leech, 3 parts of dragon's blood, 3 parts of big gun first pearl, 3 parts of centipede.
2. according to claim 1 a kind of for treating the preparation method of cardiopathic Chinese patent drug, it is characterised in that: by institute
It states each raw material to dry, removes impurity, after crushing, cross 120 meshes, take the lower drug of sieve, be uniformly mixed and Chinese patent drug is made.
3. according to claim 2 a kind of for treating the preparation method of cardiopathic Chinese patent drug, it is characterised in that: described
Chinese patent drug is electuary, tablet, water-bindered pill agent or capsule.
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Citations (2)
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CN1840077A (en) * | 2006-01-21 | 2006-10-04 | 张忠 | Medicine for treating coronary heart disease |
CN101129825A (en) * | 2007-08-14 | 2008-02-27 | 张伟 | Traditional Chinese medicine for preventing relapse of coronary disease |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN1840077A (en) * | 2006-01-21 | 2006-10-04 | 张忠 | Medicine for treating coronary heart disease |
CN101129825A (en) * | 2007-08-14 | 2008-02-27 | 张伟 | Traditional Chinese medicine for preventing relapse of coronary disease |
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Title |
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刘国清等: "花虫胶囊抗缺氧作用的临床观察", 《西南军医》 * |
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Application publication date: 20190723 |