CN109966354A - A kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch and preparation method thereof - Google Patents

A kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch and preparation method thereof Download PDF

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Publication number
CN109966354A
CN109966354A CN201711463902.9A CN201711463902A CN109966354A CN 109966354 A CN109966354 A CN 109966354A CN 201711463902 A CN201711463902 A CN 201711463902A CN 109966354 A CN109966354 A CN 109966354A
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radix caulophylli
blood circulation
blood stasis
promoting
patch
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李晓静
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

The invention discloses a kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patches and preparation method thereof, are made of adherent layer, hydrogel layer and back sheet；Hydrogel layer is using Chinese medicine Radix Caulophylli, three face knives, henry chloranthus herb, Rhizoma Polygoni suffulti, button seven, be aided with again sesame oil, glycerol, 75% ethyl alcohol, Arabic gum, polyvinyl alcohol, Acritamer 940, to hydroxy carboxylic acid ethyl ester, water, prepare hydrogel layer through sorting, heating, cooling, uniformly mixed step；The present invention has effects that promoting blood circulation to remove blood stasis, dispelling wind and eliminating dampness, promoting qi circulation and relieving pain, relieving rigidity of muscles and knitting bone, cooling blood and hemostasis；Internal lesion caused by overexertion, pain in waist and lower extremities bring pain are cured mainly, solves operation to the side effect of human body bring and inconvenience；Easy sticker of the present invention is easily taken off, and safe ready is suitable for people of all ages.

Description

A kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch and preparation method thereof
Technical field
The present invention relates to technical field of traditional Chinese medicines, espespecially a kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch and preparation method thereof.
Background technique
Plaster is one kind of Chinese medicine external, and ancient name is thin paste, plaster is mainly used to treat boil, detumescence pain etc., due to cream Medicine is used for fleshy exterior plaster, so taking the drug of strong odor in plaster, and is subject to priming and leads group medicine, the through disease of opening block and activating stagnancy Institute.The plaster stimulation nerve endings for being affixed on body surface expands blood vessel by reflection, promotes local blood circulation, improves surrounding tissue Nutrition reaches detumescence, anti-inflammatory and analgesic purpose.Chinese medical is of extensive knowledge and profound scholarship, and stream length, middle medical drugs grow everywhere, are in a steady stream The Nature assigns that we are inexhaustible, with nexhaustible healthy source, so, middle medical drugs are subjective flexibly, with strong points.Fortune Hormone-free, not braking, do not take out hydrops with traditional Chinese medicine, systemic therapy is whole to improve, sample and solid, reaches promoting the circulation of qi lively atmosphere, Can penetrate skin generate anti-inflammatory, relieve pain, activate blood circulation and disperse blood clots, network, strengthening the muscles and bones are walked in nourishing qi and blood, promoting menstruation, relaxing tendons and activating collaterals is had one's ideas straightened out The effect of bone, expelling wind and clearing away cold.But middle medical drugs it is different doctor's medication otherness it is too big, generally use medicament and treated, Mostly oral medicine and injection, but oral drugs and the equal toxic side effect of injection, can generate through liver head allergy effect and alimentary canal Release light reaction, easily cause adverse reaction, thus can bring safety problem to patient.
Summary of the invention
A kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch of the present invention and preparation method thereof, can solve the deficiency of above-mentioned technology, It is made of adherent layer, hydrogel layer and back sheet；The hydrogel layer is using Chinese medicine Radix Caulophylli, three face knives, henry chloranthus herb, red Radix Notoginseng, button seven, then be aided with sesame oil, glycerol, 75% ethyl alcohol, Arabic gum, polyvinyl alcohol, Acritamer 940, to hydroxy carboxylic acid Ethyl ester, water prepare hydrogel layer through sorting, heating, cooling, uniformly mixed step, realize clearing heat and detoxicating, promoting blood circulation to remove blood stasis patch Purpose.
To achieve the goals above, the technical solution of the invention is as follows: a kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch and The raw material components of preparation method hydrogel layer: Radix Caulophylli 4%~6%, three face knives 3%~4%, henry chloranthus herb 2%~4%, Rhizoma Polygoni suffulti 1% ~3%, button 7 1%~3%, sesame oil 1%~2%, the ethyl alcohol 25%~27% of glycerol 1%~2%, 75%, Arabic gum 1%~2%, poly- second Enol 1%~2%, Acritamer 940 1%~2%, to hydroxy carboxylic acid ethyl ester 1%~3%, water 45%~55%.
Preparation method of the invention: steps are as follows:
(1) by Radix Caulophylli 4%~6%, three face knives 3%~4%, the henry chloranthus herb 2%~4%, Rhizoma Polygoni suffulti 1%~3%, button in raw material components 7 1%~3% respectively clean, crush, be added in 75% ethyl alcohol mix it is spare；
(2) after the water in above-mentioned raw materials component being heated to 95 DEG C, heat preservation 1 hour, glycerol, Arabic gum, sesame oil, card wave is added Nurse；
(3) by step (2) treated mixture is cooled to 45 DEG C when, polyvinyl alcohol is added, to hydroxy carboxylic acid ethyl ester, sufficiently stirs It mixes uniformly mixed；
(4) step (1) treated mixture is added through step (3) treated mixture, is uniformly mixed to get water Gel layer；
(5) it by hydrogel layer, adherent layer, backing, is coated and cuts out in water-setting rubber coating group；
(6) three face knife promoting blood circulation to remove blood stasis of the Radix Caulophylli patch obtained through step (5) shearing is dried in the air 24 hours, until moisture content is 65%, i.e., Obtain three face knife promoting blood circulation to remove blood stasis of a kind of Radix Caulophylli patch of the invention.
Main ingredient composition effect of the present invention and effect:
Radix Caulophylli: there is promoting blood circulation to remove blood stasis, dispelling wind and eliminating dampness, promoting qi circulation and relieving pain；Main irregular menstruation, dysmenorrhea, postpartum abdominal pain due to blood stasis, stomach duct and abdomen are cold Bitterly, the effect of the diseases such as traumatic injury, rheumatic arthralgia；
Three face knives: there is heat-clearing, promoting blood circulation, removing toxic substances；For controlling the function of the diseases such as pharyngodynia with dryness, traumatic injury, lumbago, skelalgia of rheumatism, furuncle Effect；
Henry chloranthus herb: there is the effect of energy removing toxicity for detumescence, promoting blood circulation to remove blood stasis, the diseases such as treating rheumatic arthritis, bacillary dysentery；
Rhizoma Polygoni suffulti: there is relieving rigidity of muscles and knitting bone, cooling blood and hemostasis, analgesic efficacy；For traumatic injury, fracture, internal lesion caused by overexertion, stomachache, spits blood, collapses The effect of diseases such as leakage, dysmenorrhea, dysentery；
Button seven: there is removing blood stasis for promoting tissue regeneration, analgesic hemostatic；For traumatic injury, rheumatic arthritis, stomachache;Traumatic hemorrhage is controlled in external application The effect of equal diseases；
Sesame oil: there is moistening dryness for relaxing bowels, removing toxic substances, myogenic；Control dry constipation of intestines, roundworm, dyspeptic abdominalgia, sore swells, ulcer, scabies, skin The effect of diseases such as chap.
The utility model has the advantages that three face knife promoting blood circulation to remove blood stasis of a kind of Radix Caulophylli patch of the invention is with promoting blood circulation to remove blood stasis, dispelling wind and eliminating dampness, row The effect of gas analgesic, relieving rigidity of muscles and knitting bone, cooling blood and hemostasis；Internal lesion caused by overexertion, pain in waist and lower extremities bring pain are cured mainly, operation is solved and human body is brought Side effect and inconvenience；Easy sticker of the present invention is easily taken off, and safe ready is suitable for people of all ages.
Specific embodiment
Principles and features of the present invention are described with reference to embodiments, the given examples are served only to explain the present invention, It is not intended to limit the scope of the present invention.
Embodiment 1
1) three face knife promoting blood circulation to remove blood stasis of a kind of Radix Caulophylli of the invention patch, is made of adherent layer, hydrogel layer and backing.The water The raw material components of gel layer: Radix Caulophylli 4%, three face knives 4%, henry chloranthus herb 2%, Rhizoma Polygoni suffulti 1%, button 7 2%, sesame oil 2%, glycerol 2%, 75% ethyl alcohol 26%, Arabic gum 2%, polyvinyl alcohol 2%, Acritamer 940 2%, to hydroxy carboxylic acid ethyl ester 3%, water 50%.
2) preparation method of the invention: steps are as follows:
(1) Radix Caulophylli 4%, three face knives 4%, henry chloranthus herb 2%, Rhizoma Polygoni suffulti 1%, button 7 2% in raw material components are cleaned respectively, powder It is broken, be added in 75% ethyl alcohol mix it is spare；
(2) after the water in above-mentioned raw materials component being heated to 95 DEG C, heat preservation 1 hour, glycerol, Arabic gum, sesame oil, card wave is added Nurse 940；
(3) by step (2) treated mixture is cooled to 45 DEG C when, polyvinyl alcohol is added, to hydroxy carboxylic acid ethyl ester, sufficiently stirs It mixes uniformly mixed；
(4) step (1) treated mixture is added through step (3) treated mixture, is uniformly mixed to get water Gel layer；
(5) it by hydrogel layer, adherent layer, backing, is coated and cuts out in water-setting rubber coating group；
(6) three face knife promoting blood circulation to remove blood stasis of the Radix Caulophylli patch obtained through step (5) shearing is dried in the air 24 hours, until moisture content is 65%, i.e., Obtain three face knife promoting blood circulation to remove blood stasis of a kind of Radix Caulophylli patch of the invention.
Embodiment 2
1) three face knife promoting blood circulation to remove blood stasis of a kind of Radix Caulophylli of the invention patch, is made of adherent layer, hydrogel layer and backing.The water The raw material components of gel layer: Radix Caulophylli 5%, three face knives 3%, henry chloranthus herb 3%, Rhizoma Polygoni suffulti 2%, button 7 1%, sesame oil 1%, glycerol 1%, 75% ethyl alcohol 25%, Arabic gum 1%, polyvinyl alcohol 1%, Acritamer 940 1%, to hydroxy carboxylic acid ethyl ester 1%, water 55%.
2) preparation method of the invention: steps are as follows:
(1) Radix Caulophylli 5%, three face knives 3%, henry chloranthus herb 3%, Rhizoma Polygoni suffulti 2%, button 7 1% in raw material components are cleaned respectively, powder It is broken, be added in 75% ethyl alcohol mix it is spare；
(2) after the water in above-mentioned raw materials component being heated to 95 DEG C, heat preservation 1 hour, glycerol, Arabic gum, sesame oil, card wave is added Nurse 940；
(3) by step (2) treated mixture is cooled to 45 DEG C when, polyvinyl alcohol is added, to hydroxy carboxylic acid ethyl ester, sufficiently stirs It mixes uniformly mixed；
(4) step (1) treated mixture is added through step (3) treated mixture, is uniformly mixed to get water Gel layer；
(5) it by hydrogel layer, adherent layer, backing, is coated and cuts out in water-setting rubber coating group；
(6) three face knife promoting blood circulation to remove blood stasis of the Radix Caulophylli patch obtained through step (5) shearing is dried in the air 24 hours, until moisture content is 65%, i.e., Obtain three face knife promoting blood circulation to remove blood stasis of a kind of Radix Caulophylli patch of the invention.
Embodiment 3
1) three face knife promoting blood circulation to remove blood stasis of a kind of Radix Caulophylli of the invention patch, is made of adherent layer, hydrogel layer and backing.The water The raw material components of gel layer: Radix Caulophylli 6%, three face knives 3%, henry chloranthus herb 4%, Rhizoma Polygoni suffulti 3%, button 7 3%, sesame oil 1.5%, glycerol 1.5%, 75% ethyl alcohol 27%, Arabic gum 1.5%, polyvinyl alcohol 1.5%, Acritamer 940 1%, to hydroxy carboxylic acid ethyl ester 2%, water 45%。
2) preparation method of the invention: steps are as follows:
(1) Radix Caulophylli 6%, three face knives 3%, henry chloranthus herb 4%, Rhizoma Polygoni suffulti 3%, button 7 3% in raw material components are cleaned respectively, powder It is broken, be added in 75% ethyl alcohol mix it is spare；
(2) after the water in above-mentioned raw materials component being heated to 95 DEG C, heat preservation 1 hour, glycerol, Arabic gum, sesame oil, card wave is added Nurse 940；
(3) by step (2) treated mixture is cooled to 45 DEG C when, polyvinyl alcohol is added, to hydroxy carboxylic acid ethyl ester, sufficiently stirs It mixes uniformly mixed；
(4) step (1) treated mixture is added through step (3) treated mixture, is uniformly mixed to get water Gel layer；
(5) it by hydrogel layer, adherent layer, backing, is coated and cuts out in water-setting rubber coating group；
(6) three face knife promoting blood circulation to remove blood stasis of the Radix Caulophylli patch obtained through step (5) shearing is dried in the air 24 hours, until moisture content is 65%, i.e., Obtain three face knife promoting blood circulation to remove blood stasis of a kind of Radix Caulophylli patch of the invention.
The above, embodiment is only that preferred embodiments of the present invention will be described, not to of the invention Range is defined, and under the premise of not departing from the spirit of the technology of the present invention, this field engineers and technicians are to skill of the invention The various changes and improvements that art scheme is made, should fall within the scope of protection determined by the claims of the present invention.

Claims (1)

1. a kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch and preparation method thereof, is made of adherent layer, hydrogel layer and back sheet；Its It is characterized in that: hydrogel layer raw material components: Radix Caulophylli 4%~6%, three face knives 3%~4%, henry chloranthus herb 2%~4%, Rhizoma Polygoni suffulti 1%~ 3%, button 7 1%~3%.
CN201711463902.9A 2017-12-28 2017-12-28 A kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch and preparation method thereof Pending CN109966354A (en)

Priority Applications (1)

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CN201711463902.9A CN109966354A (en) 2017-12-28 2017-12-28 A kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711463902.9A CN109966354A (en) 2017-12-28 2017-12-28 A kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch and preparation method thereof

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Publication Number Publication Date
CN109966354A true CN109966354A (en) 2019-07-05

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