CN108283683A - A kind of detoxification analgesic plaster and preparation method thereof - Google Patents
A kind of detoxification analgesic plaster and preparation method thereof Download PDFInfo
- Publication number
- CN108283683A CN108283683A CN201810216487.5A CN201810216487A CN108283683A CN 108283683 A CN108283683 A CN 108283683A CN 201810216487 A CN201810216487 A CN 201810216487A CN 108283683 A CN108283683 A CN 108283683A
- Authority
- CN
- China
- Prior art keywords
- plaster
- weight
- parts
- detoxification
- spice
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
Abstract
The invention discloses a kind of detoxification analgesic plaster and preparation method thereof, the plaster includes frankincense, myrrh, dragon's blood, keel, yellow lead and vegetable oil.The synergistic effect that the plaster of the present invention passes through Chinese medicine in frankincense, myrrh, dragon's blood, keel and yellow lead five, play the effect for treating a variety of diseases, the plaster of the present invention has promoting blood circulation and removing blood stasis, anti-inflammation detumescence, removing blood stasis and hemostasis, expelling pus and promoting granulation, dispelling wind and eliminating dampness, to furuncle, swollen, sore, vasculitis gangrene, non-healing wounds have preferable effect, traumatic injury is can be also used for, knife axe is stabbed blood and gone out incessantly, rheumatic arthritis, painful swelling of joints and osteoproliferation are found by experiment that the plaster of the present invention has the effect of significantly draw out the pus detumescence, analgesic and hemostasis in addition；Each middle the effective elements of the medicine can adequately be extract by the preparation method of plaster of the present invention, and preparation method is simple, easy to operate.
Description
Technical field
The invention belongs to pharmaceutical technology fields, specifically, being related to a kind of detoxification analgesic plaster and preparation method thereof.
Background technology
Furuncle is the infection of a kind of suppurative hair follicle and hair follicle deep surrounding tissue, often expands to subcutaneous tissue, furuncle long hair
It is born in hair follicle and the more rich position of sebaceous glands, it is more such as neck, head, face, back, armpit, pars inguinalis and perineum and shank
A furuncle simultaneously or repeated in each portion of body, referred to as dothienesis, i.e., multiple furuncle, not only number is more, and this furuncle is rigid
Good, another furuncle comes out again, rises one after another, repeated, the course of disease is longer, furuncle may be by bacterium infection, air or food
Object allergy, life stress, health do not eat, are sick, resist force difference, some drugs, eat excessive junk food, wound infection, blood
The factors such as poisoning or thyroid gland defect cause.It is both bitterly and unbecoming, can also leave scar sometimes, even has life danger once in a while
Danger.
Traumatic injury refers to soft tissue injury of the people caused by the reasons such as falling, beating, touch, crack between the teeth, with swelling, pain for main table
It is existing.Chinese traditional treatment traumatic injury has thousands of years history, and ancient " traumatic injury " is referred to as the introduction of all wounds, mostly because of outer force effect,
Or it overexerts and causes in the case of itself fault.Chinese medicine hinders all muscles and bones because caused by external force acts on human body
Damage, extravasated blood swelling and pain, derangement of Qi and blood, blockage of main and collateral channels are impaired etc. down to internal organs, are referred to as traumatic injury.
For a long time, furuncle, traumatic injury are treated mostly based on massage, hot compress, west plaster, but there are physical therapy times
Length, slowly effect, patient endure the drawbacks such as pain torment to the fullest extent for a long time, and certain antiphlogistics and promoting blood circulation class drug are hormone medicine, right
Body is irritant, and long-term use will produce tolerance and certain side effect.
Plaster is one of main method of external treatment with Chinese medicine, as one piece of rarity of my Chinese nation, is played always for many years
Irreplaceable role.Practice was continued to use by 1,100, fully proves that plaster has " easy to use, cheap, effect
Rapidly, significant in efficacy " the advantages that.
Since plaster is directly applied to body surface, and the most smell of drug for making paste is denseer, interior by infiltrating through skin
Transmit scriptures network, internal organs, the effects that it is wet to play regulating the qi flowing in the channels blood, degrading the channel, cold dispelling, pain of subsiding a swelling, therefore plaster use scope is extensive, be easy to by
People receive, and present plaster is the stronger plaster of specific aim made for a kind of disease mostly, cannot can reach a kind of
The effect of a variety of diseases of plaster treatment.
For these reasons, special to propose the application.
Invention content
In order to solve problem above of the existing technology, the present invention provides a kind of detoxification analgesic plaster and its preparation sides
Method, plaster of the invention have promoting blood circulation and removing blood stasis, anti-inflammation detumescence, removing blood stasis and hemostasis, expelling pus and promoting granulation, dispelling wind and eliminating dampness, to furuncle, swollen, sore
Ulcer, vasculitis gangrene, non-healing wounds have preferable effect, can be also used for traumatic injury, knife axe is stabbed blood and gone out incessantly, wind
Wet arthritis, painful swelling of joints and osteoproliferation.
The first object of the present invention provides a kind of detoxification analgesic plaster, the plaster include frankincense, myrrh, dragon's blood,
Keel, yellow lead and vegetable oil.
Frankincense is that long ovum row drips emulsus, similar round particle or is bonded into the irregular block to differ in size, and surface is yellowish-white
Color, translucent, yellow-white powder deposits then color burn long, be used for chest impediment and cardialgia, gastral cavity pain, dysmenorrhoea Amenorrhea, postpartum stasis,
Abdominal mass abdominal pain, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore.
Myrrh has the effect of scattered stasis pain, detumescence and promoting granulation.It is usually used in chest impediment and cardialgia, gastral cavity pain, dysmenorrhoea Amenorrhea, postpartum
Stasis blocking , Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, traumatic injury, the treatment of the illnesss such as carbuncle swells sore.
Dragon's blood, which is that the resin of babassu Sanguis Draxonis fruit exudation is processed, to be made.Be distributed in Indonesia Java,
Sumatera, Borneo etc..With promoting blood circulation analgesic therapy, the effect of removing blood stasis and hemostasis, myogenic sore, it to be used for traumatic injury, trusted subordinate's stasis of blood
Bitterly, traumatic hemorrhage, sore are not held back.
Keel, alias Lu Hu lose life, that gal bone, Os Draconis, calcined Dragon's bone, five OS DRACONISs, bluenessization keel, OS DRACONIS, Bai Long
Bone.For ancient times mammal as if the fossil of the skeleton of class, rhinoceros class, Hippocampal cortex etc..After digging out keel, soil and miscellaneous is removed
Matter.Five OS DRACONIS matter are crisp, and after being unearthed, dew empties easily broken in gas, common writing paper made from bamboo stickup.With transquilization with heavy material relieving convulsion peace
God, arrest sweating controlling nocturnal emission with astringent drugs, stop blooding puckery intestines, myogenic sore.It is demented to control frightened epilepsy, palpitation is forgetful, insomnia and dreamful sleep, spontaneous sweating, stranguria with turbid discharge of passing out semen,
Hematemesis is had blood in stool, and under uterine bleeding band, rush down dysentery rectal prolapse, ulcer does not close up long.
Yellow lead is also known as minium, red lead, red lead, Tao Dan, and crocus, matter weight is powdered, and main component is lead tetroxide, pure
Degree is required 95% or more.Main function is removing toxic substances and promoting tissue regeneration, and desinsection is antipruritic；Promoting expectoration to arrest convulsion attacks malicious preventing malaria.
Further, according to parts by weight, the plaster includes frankincense 3-15 parts by weight, myrrh 2-13 parts by weight, dragon's blood
4-13 parts by weight, keel 0.5-1.5 parts by weight, yellow lead 200-300 parts by weight and vegetable oil 450-550 parts by weight.
Further, according to parts by weight, the plaster includes 9 parts by weight of frankincense, 7 parts by weight of myrrh, 9 weight of dragon's blood
Part, 500 parts by weight of 1 parts by weight of keel, 250 parts by weight of yellow lead and vegetable oil.
Further, the vegetable oil is sesame oil.
Vegetable oil selection is conducive to operate with the pure sesame oil of quality since foam is few when it is refined oil in the present invention, and makes
At plaster bright in color, adhesive quality it is good, the present inventor has found by a large number of experiments, using the treatment analgesic hemostatic of sesame oil
Effect is more preferable.
The second object of the present invention provides a kind of preparation method of the detoxification analgesic plaster, the preparation method
Include the following steps：
(1) each raw material for standby is weighed respectively according to the parts by weight of constitutive material；
(2) frankincense weighed, myrrh, dragon's blood and keel are ground respectively, obtain spice, spice is divided into weight not
Deng two parts, spice A and spice B；
(3) vegetable oil is placed in pot, after low-grade fever spice A put into, continue to heat and be stirred continuously, until spice fry to
Good rear filter and remove residue is fried in surface dark brown, internal sallow stopping, and filtrate is old oil；
(4) the old oil is continued to temper, continues heat temperature raising, is then changed to moderate heat, continues to boil, control the fire of oil
It waits, obtains medicine oil；
(5) yellow lead weighed will be added in medicine oil, stirs while adding, obtain sticky lotion；
(6) lotion is put into cold water and is impregnated；
(7) lotion after immersion is placed in container, is dissolved with slow boiling, spice B is added, then lotion is placed in by stirring
The detoxification analgesic plaster is obtained on brown paper or medicated plaster cloth.
Further, the grain size of spice is 100-140 mesh in step (2), and the weight ratio of spice A and spice B are 1:3-5.
The present invention first refines a part of spice and vegetable oil, and the active ingredient in spice is made to be immersed in vegetable oil, can
Preferably to improve the therapeutic effect of plaster, adequately absorbed conducive to human body, it is mixed in the medicine oil with tanning after another part grinding
It closes, use when is directly pasted on human body, is conducive to absorb, reaches better therapeutic effect.
Further, heating temperature is 200-240 DEG C in step (3).
Further, the duration and degree of heating that oil refining control is refined oil in step (4), first sees thermometer, reaches defined temperature and is
Stop；Second is observation oil smoke color, starts as light cyan, is gradually black and dense, and then is white dense smoke, and white cigarette is straight when calm
It is long；Third is to see oil bloom, and when boiling starts, oil bloom mostly in pot wall periphery, stop when oil bloom are assembled to pot center；4th
It sees dropping into a bead, takes a little medicine oil drop in water, the beading that do not scatter stops.
Further, heating temperature is 300-340 DEG C in step (4).
Further, drying and grinding processing is carried out before yellow lead is added in step (5), grain size is 90-110 mesh.
Further, it is added while stirring when yellow lead is added in step (5), the direction of stirring in one direction, is stirred always
Mix sticky lotion, lotion not grain hand, wire drawing is constantly preferably, really up to the mark then old, excessively viscous then tender.
Further, lotion impregnates 7 days in cold water in step (6), changes a water every day.
Compared with prior art, beneficial effects of the present invention are as follows：
(1) plaster of the invention is played by the synergistic effect of Chinese medicine in frankincense, myrrh, dragon's blood, keel and yellow lead five
The effect of a variety of diseases is treated, plaster of the invention has promoting blood circulation and removing blood stasis, anti-inflammation detumescence, removing blood stasis and hemostasis, expelling pus and promoting granulation, wind-dispelling
Dehumidifying, to furuncle, swollen, sore, vasculitis gangrene, non-healing wounds have preferable effect, can be also used for traumatic injury, knife axe
It stabs blood to go out incessantly, rheumatic arthritis, painful swelling of joints and osteoproliferation, is found by experiment that the plaster of the present invention has in addition
The effect of obvious draw out the pus detumescence, analgesic and hemostasis；
(2) each middle the effective elements of the medicine can adequately be extract, preparation method by the preparation method of plaster of the present invention
Simply, easy to operate.
Specific implementation mode
To make the object, technical solutions and advantages of the present invention clearer, technical scheme of the present invention will be carried out below
Detailed description.Obviously, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are obtained all without making creative work
Other embodiment belongs to the range that the present invention is protected.
Embodiment 1
The detoxification analgesic plaster of the present embodiment includes frankincense 3g, myrrh 2g, dragon's blood 4g, keel 0.5g, yellow lead 200g and fiber crops
Oily 450g.
The preparation method of the detoxification analgesic plaster of the present embodiment, includes the following steps：
(1) each raw material for standby is weighed respectively according to the parts by weight of constitutive material；
(2) frankincense weighed, myrrh, dragon's blood and keel are ground respectively, obtain spice, the grain size of spice is 100
Spice is divided into not equal two parts of weight by mesh, and the weight ratio of spice A and spice B, spice A and spice B are 1:3；
(3) sesame oil is placed in pot, spice A is put into after low-grade fever, continues to be heated to 200 DEG C, and be stirred continuously, until medicine
Material is fried to surface dark brown, internal sallow stopping, frying good rear filter and remove residue, and filtrate is old oil；
(4) the old oil is continued to temper, continues to heat to 300 DEG C, be then changed to moderate heat, continues to boil, controlled
The duration and degree of heating of oil, obtains medicine oil；
Wherein, the duration and degree of heating of oil refining is controlled, first sees thermometer, and it is to stop to reach defined temperature；Second is observation oil
Cigarette color starts as light cyan, is gradually black and dense, and then is white dense smoke, and white cigarette is directly grown when calm；Third is to see oil bloom,
When boiling starts, oil bloom mostly in pot wall periphery, stop when oil bloom are assembled to pot center；4th sees dropping into a bead, takes few
Perhaps in water, the beading that do not scatter stops medicine oil drop；
(5) yellow lead weighed will be added in medicine oil, milled processed is dried in yellow lead before being added, grain size is 90 mesh, side
Be added side stirring, the direction of stirring always in one direction, stirs into sticky lotion, lotion not grain hand, wire drawing constantly preferably,
It is really up to the mark then old, it is excessively viscous then tender, obtain sticky lotion；
(6) lotion is put into cold water and is impregnated, impregnated 7 days, change a water every day；
(7) lotion after immersion is placed in container, is dissolved with slow boiling, spice B is added, stirred with willow branch, then used
Lotion is placed on brown paper or medicated plaster cloth by willow branch obtains the detoxification analgesic plaster.
Embodiment 2
The detoxification analgesic plaster of the present embodiment includes frankincense 9g, myrrh 7g, dragon's blood 9g, keel 1g, yellow lead 250g and sesame oil
500g。
The preparation method of the detoxification analgesic plaster of the present embodiment, includes the following steps：
(1) each raw material for standby is weighed respectively according to the parts by weight of constitutive material；
(2) frankincense weighed, myrrh, dragon's blood and keel are ground respectively, obtain spice, the grain size of spice is 120
Spice is divided into not equal two parts of weight by mesh, and the weight ratio of spice A and spice B, spice A and spice B are 1:4；
(3) sesame oil is placed in pot, spice A is put into after low-grade fever, continues to be heated to 220 DEG C, and be stirred continuously, until medicine
Material is fried to surface dark brown, internal sallow stopping, frying good rear filter and remove residue, and filtrate is old oil；
(4) the old oil is continued to temper, continues to heat to 320 DEG C, be then changed to moderate heat, continues to boil, controlled
The duration and degree of heating of oil, obtains medicine oil；
Wherein, the duration and degree of heating of oil refining is controlled, first sees thermometer, and it is to stop to reach defined temperature；Second is observation oil
Cigarette color starts as light cyan, is gradually black and dense, and then is white dense smoke, and white cigarette is directly grown when calm；Third is to see oil bloom,
When boiling starts, oil bloom mostly in pot wall periphery, stop when oil bloom are assembled to pot center；4th sees dropping into a bead, takes few
Perhaps in water, the beading that do not scatter stops medicine oil drop；
(5) yellow lead weighed will be added in medicine oil, milled processed is dried in yellow lead before being added, grain size is 100 mesh, side
Be added side stirring, the direction of stirring always in one direction, stirs into sticky lotion, lotion not grain hand, wire drawing constantly preferably,
It is really up to the mark then old, it is excessively viscous then tender, obtain sticky lotion；
(6) lotion is put into cold water and is impregnated, impregnated 7 days, change a water every day；
(7) lotion after immersion is placed in container, is dissolved with slow boiling, spice B is added, stirred with willow branch, then used
Lotion is placed on brown paper or medicated plaster cloth by willow branch obtains the detoxification analgesic plaster.
Embodiment 3
The detoxification analgesic plaster of the present embodiment include frankincense 15g, myrrh 13g, dragon's blood 13g, keel 1.5g, yellow lead 300g and
Sesame oil 550g.
The preparation method of the detoxification analgesic plaster of the present embodiment, includes the following steps：
(1) each raw material for standby is weighed respectively according to the parts by weight of constitutive material；
(2) frankincense weighed, myrrh, dragon's blood and keel are ground respectively, obtain spice, the grain size of spice is 140
Spice is divided into not equal two parts of weight by mesh, and the weight ratio of spice A and spice B, spice A and spice B are 1:5；
(3) sesame oil is placed in pot, spice A is put into after low-grade fever, continues to be heated to 240 DEG C, and be stirred continuously, until medicine
Material is fried to surface dark brown, internal sallow stopping, frying good rear filter and remove residue, and filtrate is old oil；
(4) the old oil is continued to temper, continues to heat to 340 DEG C, be then changed to moderate heat, continues to boil, controlled
The duration and degree of heating of oil, obtains medicine oil；
Wherein, the duration and degree of heating of oil refining is controlled, first sees thermometer, and it is to stop to reach defined temperature；Second is observation oil
Cigarette color starts as light cyan, is gradually black and dense, and then is white dense smoke, and white cigarette is directly grown when calm；Third is to see oil bloom,
When boiling starts, oil bloom mostly in pot wall periphery, stop when oil bloom are assembled to pot center；4th sees dropping into a bead, takes few
Perhaps in water, the beading that do not scatter stops medicine oil drop；
(5) yellow lead weighed will be added in medicine oil, milled processed is dried in yellow lead before being added, grain size is 110 mesh, side
Be added side stirring, the direction of stirring always in one direction, stirs into sticky lotion, lotion not grain hand, wire drawing constantly preferably,
It is really up to the mark then old, it is excessively viscous then tender, obtain sticky lotion；
(6) lotion is put into cold water and is impregnated, impregnated 7 days, change a water every day；
(7) lotion after immersion is placed in container, is dissolved with slow boiling, spice B is added, stirred with willow branch, then used
Lotion is placed on brown paper or medicated plaster cloth by willow branch obtains the detoxification analgesic plaster.
1 analgesic experiment of test example
Experimental animal：Kunming mouse, weight 22-26g are provided by Hubei Prov. Academy of Medical Sciences's Experimental Animal Center；
Mouse writhing is tested
22-24g Kunming mouses 80 are selected, 4 groups, i.e. control group and 3 plaster groups are randomly divided into, by four groups of mouse web portions
Depilation, area are 1.5cm × 1.5cm, and without skin injury, and plaster group 1-3 is respectively to be affixed on the embodiment 1-3 plaster prepared
At depilation, control group pastes gauze at depilation, uses immobilization with adhesive tape.0.7% ice is injected to the mouse of control group and plaster group respectively
Acetum 0.1/10g weight observes and records after injection algogen each mouse writhing number in 20min, the results are shown in Table 1.
Table 1
| Group | Size of animal (only) | Mean writhes number |
| Control group | 20 | 70.2 |
| Plaster group 1 | 20 | 22.3 |
| Plaster group 2 | 20 | 21.6 |
| Plaster group 3 | 20 | 22.9 |
As can be seen from the above table, the mouse mean writhes number of plaster group 1-3 is significantly reduced compared with control group, can prove this
The plaster of invention has preferable analgesic effect.
Test example 2
Mouse docking haemostatic effect experiment
Experimental animal：Kunming mouse, weight 18-22g, by being provided by Hubei Prov. Academy of Medical Sciences's Experimental Animal Center.
Normal healthy mice 40 is equally divided into four groups, i.e. Normal group and plaster group 1-3.Normal group is not added with any drug,
Plaster group 1-3 is plaster prepared by embodiment 1-3, plaster is placed in displaying bottle respectively, sterilization treatment, by Normal group and
After the mouse of plaster group 1-3 cuts off the one third of tail length with operating scissors respectively, docking wound is inserted into displaying bottle immediately, together
When timing, calculate blood flow dwell time mouse amount of bleeding, be shown in Table 2.
Table 2
| Group | Bleeding stopping period (s) | Amount of bleeding (mg) |
| Plaster group 1 | 63.5 | 10.2 |
| Plaster group 2 | 60.2 | 10.3 |
| Plaster group 3 | 64.5 | 10.6 |
| Normal group | 98.5 | 16.3 |
As can be seen from the above table, plaster using the present invention has preferable haemostatic effect compared with the control group.
3 mouse of test example is subcutaneously drawn out the pus experiment
Test method：Kunming male mice 20, back shave shaving are chosen, shaving area is lost hair or feathers with depilatory cream, is carried on the back
After portion's depilation for 24 hours, after being anaesthetized with 0.5% yellow Jackets (1ml/100g), golden yellow Portugal is subcutaneously injected without hair-fields in mouse
Grape coccus liquid (a concentration of 4.02 × 108Cfu/ml) only, after injecting staphylococcus aureus for 24 hours, 20 mouse are put down by 0.1ml/
Two groups are divided into, control group and plaster group, control group do not stick any drug, and plaster group is applied with embodiment 1 to each mouse and makes
Standby plaster, daily application is primary, continuous to apply 7 days.
Test result：The 2nd day after hypodermic injection staphylococcus aureus, there is purulence in control group and plaster group mouse back
Packet, second day and the 4th day plaster group speed ratio Normal group of subsiding a swelling significantly improve, later stage 5-7 days, the abscess of plaster group
Rate of subsiding a swelling is fast, and plaster prepared by the present invention can accelerate abscess to disappear, and have the function of detumescence of preferably drawing out the pus, and the results are shown in Table
3。
Table 3
Note：It is abscess that abscess detumescence rate, which is less than 0, is more than 0 for detumescence.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of detoxification analgesic plaster, which is characterized in that the plaster includes frankincense, myrrh, dragon's blood, keel, yellow lead and plant
Object oil.
2. detoxification analgesic plaster according to claim 1, which is characterized in that according to parts by weight, the plaster includes breast
Fragrant 3-15 parts by weight, myrrh 2-13 parts by weight, dragon's blood 4-13 parts by weight, keel 0.5-1.5 parts by weight, yellow lead 200-300 weight
Part and vegetable oil 450-550 parts by weight.
3. detoxification analgesic plaster according to claim 1, which is characterized in that according to parts by weight, the plaster includes breast
Fragrant 9 parts by weight, 7 parts by weight of myrrh, 9 parts by weight of dragon's blood, 500 parts by weight of 1 parts by weight of keel, 250 parts by weight of yellow lead and vegetable oil.
4. according to the detoxification analgesic plaster described in claim 1-3 any one, which is characterized in that the vegetable oil is fiber crops
Oil.
5. a kind of preparation method of the detoxification analgesic plaster described in claim 1-4 any one, which is characterized in that the system
Preparation Method includes the following steps：
(1) each raw material for standby is weighed respectively according to the parts by weight of constitutive material；
(2) frankincense weighed, myrrh, dragon's blood and keel are ground respectively, obtain spice, spice is divided into what weight did not waited
Two parts, spice A and spice B；
(3) vegetable oil is placed in pot, spice A is put into after low-grade fever, continues to heat and be stirred continuously, until spice is fried to surface
Good rear filter and remove residue is fried in dark brown, internal sallow stopping, and filtrate is old oil；
(4) the old oil is continued to temper, continues heat temperature raising, is then changed to moderate heat, continues to boil, controlled the duration and degree of heating of oil, obtain
To medicine oil；
(5) yellow lead weighed will be added in medicine oil, stirs while adding, obtain sticky lotion；
(6) lotion is put into cold water and is impregnated；
(7) lotion after immersion is placed in container, is dissolved with slow boiling, spice B is added, then lotion is placed in ox-hide by stirring
The detoxification analgesic plaster is obtained on paper or medicated plaster cloth.
6. the preparation method of detoxification analgesic plaster according to claim 5, which is characterized in that the grain of spice in step (2)
Diameter is 100-140 mesh, and the weight ratio of spice A and spice B are 1:3-5.
7. the preparation method of detoxification analgesic plaster according to claim 5, which is characterized in that heating temperature in step (3)
It is 200-240 DEG C.
8. the preparation method of detoxification analgesic plaster according to claim 5, which is characterized in that heating temperature in step (4)
It is 300-340 DEG C.
9. the preparation method of detoxification analgesic plaster according to claim 5, which is characterized in that yellow lead is added in step (5)
Preceding progress drying and grinding processing, grain size are 90-110 mesh.
10. the preparation method of detoxification analgesic plaster according to claim 5, which is characterized in that lotion is cold in step (6)
It is impregnated 7 days in water, changes a water every day.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810216487.5A CN108283683A (en) | 2018-03-15 | 2018-03-15 | A kind of detoxification analgesic plaster and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810216487.5A CN108283683A (en) | 2018-03-15 | 2018-03-15 | A kind of detoxification analgesic plaster and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108283683A true CN108283683A (en) | 2018-07-17 |
Family
ID=62833735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810216487.5A Pending CN108283683A (en) | 2018-03-15 | 2018-03-15 | A kind of detoxification analgesic plaster and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108283683A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112915145A (en) * | 2021-01-28 | 2021-06-08 | 孙玉宝 | Purple sand cupping glass and preparation method and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20090097483A (en) * | 2008-03-11 | 2009-09-16 | 강주봉 | Composition comprising the mixed extract comprising mylabris sidae fabricius showing reduced toxicity for treating and improving leukoplakia |
| CN104510865A (en) * | 2013-09-26 | 2015-04-15 | 于兆英 | Traditional Chinese medicine powder for treating bedsore |
| CN105194351A (en) * | 2015-11-02 | 2015-12-30 | 谢树光 | Traditional Chinese medicine ointment for treating bone diseases |
| CN107536934A (en) * | 2016-06-27 | 2018-01-05 | 杨永胜 | A kind of curing pains of muscles and bones plaster |
-
2018
- 2018-03-15 CN CN201810216487.5A patent/CN108283683A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20090097483A (en) * | 2008-03-11 | 2009-09-16 | 강주봉 | Composition comprising the mixed extract comprising mylabris sidae fabricius showing reduced toxicity for treating and improving leukoplakia |
| CN104510865A (en) * | 2013-09-26 | 2015-04-15 | 于兆英 | Traditional Chinese medicine powder for treating bedsore |
| CN105194351A (en) * | 2015-11-02 | 2015-12-30 | 谢树光 | Traditional Chinese medicine ointment for treating bone diseases |
| CN107536934A (en) * | 2016-06-27 | 2018-01-05 | 杨永胜 | A kind of curing pains of muscles and bones plaster |
Non-Patent Citations (3)
| Title |
|---|
| 中公教育执业药师考试研究中心: "《中药学专业知识（一）.课堂实录》", 31 March 2017 * |
| 何敏文: "牛生水袋的治疗", 《四川畜牧兽医》 * |
| 胡献国等: "《中国膏药配方配制全书》", 30 April 2014, 辽宁科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112915145A (en) * | 2021-01-28 | 2021-06-08 | 孙玉宝 | Purple sand cupping glass and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101049466B (en) | Ointment of Chinese herbal medicine for treating burn and scald without pain, and scar, and preparation method | |
| CN108283683A (en) | A kind of detoxification analgesic plaster and preparation method thereof | |
| CN101332271A (en) | External medicine composition for treating burn and scald | |
| CN104189949B (en) | A kind of compound recipe Radix Cirsii Japonici external sthptic sponge and preparation method | |
| CN104474528A (en) | Medicine used for drainage detoxification | |
| US9421235B2 (en) | Medicine containing extracts of Ficus microcarpa for healing wounds of a diabetic patient | |
| CN106581241A (en) | Burn and scald treating traditional Chinese medicine composition | |
| CN108686092A (en) | Eliminate the Chinese medicinal aqua and preparation method thereof of scar | |
| CN102283945B (en) | Chinese herbal medicine for treating burn | |
| CN105596418A (en) | Traditional Chinese medicine used for treating second degree burn, and preparation method thereof | |
| CN104383057A (en) | Paste for mainly treating traumatic injury and preparation method of paste for mainly treating traumatic injury | |
| CN106806876A (en) | A kind of efficient prickly-heat powder | |
| CN105147848A (en) | Traditional Chinese medicine preparation for treating scalds, burns and frostbites and preparation method thereof | |
| CN104997974A (en) | Chinese medicinal preparation for treating burn and scald, and its preparation method | |
| CN104547342A (en) | Rapid hemostasis external application powder for clinical nursing and preparation method of rapid hemostasis external application powder | |
| RU2189829C1 (en) | Healing phytopreparation and method for preparing the preparation | |
| CN105012916A (en) | Medicine for burns and scalds and preparation method of medicine | |
| CN1197604C (en) | Ointment for treating burns and scalds, sore, bone tuberculosis and wounds | |
| CN102000213A (en) | Traditional Chinese herbal medicine preparation for treating burn | |
| CN109745502A (en) | The medicine vinegar for preventing and treating wind-heat poison Sheng type herpe simplex | |
| CN109288945A (en) | It is a kind of to treat osteoproliferation externally applied Chinese medicine agent and preparation method thereof | |
| CN109966354A (en) | A kind of three face knife promoting blood circulation to remove blood stasis of Radix Caulophylli patch and preparation method thereof | |
| CN109419837A (en) | A kind of swelling and pain relieving ointment and preparation method thereof | |
| Vrana et al. | FIG NO: 2 Panchadhatu Shalaka | |
| CN105012480A (en) | A Chinese medicinal ointment for treating burn and scald, and its preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180717 |