CN109419837A - A kind of swelling and pain relieving ointment and preparation method thereof - Google Patents

A kind of swelling and pain relieving ointment and preparation method thereof Download PDF

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CN109419837A
CN109419837A CN201710715210.2A CN201710715210A CN109419837A CN 109419837 A CN109419837 A CN 109419837A CN 201710715210 A CN201710715210 A CN 201710715210A CN 109419837 A CN109419837 A CN 109419837A
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parts
swelling
ointment
pain relieving
plaster
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不公告发明人
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Liang Sisheng
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Liang Sisheng
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/04Tars; Bitumens; Mineral oils; Ammonium bituminosulfonate
    • A61K35/06Mineral oils, e.g. paraffinic oils or aromatic oils based on aromatic hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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Abstract

The invention discloses a kind of swelling and pain relieving ointment and preparation method thereof, belong to field of traditional Chinese medicine preparation.Discutient and analgesic plaster is in parts by weight, comprising: 3-6 parts of Groomwell root oil, 2-7 parts of thickening agent and 10-15 parts of the plaster of paris.When manufacture, after using vegetable oil fried Asian puccoon, the Groomwell root oil that will acquire is uniformly mixed with thickening agent and the plaster of paris by setting proportion, obtains lotion.Swelling and pain relieving ointment disclosed by the invention has the effects that stronger activating microcirculation and removing stasis medicinal, anti-inflammatory analgetic, warming and activating meridian and cold dispelling by the effect of each component coordinated, effectively treat that all kinds of joints are acute, habitual strain, the pain for turning round the wounded can fast and effeciently be released, and it can be used for fast and effective healing of the sportsman because of training and competition acute sprain, pass through above-mentioned ointment, the pain for alleviating the sick and wounded process of muscles and bones in time rapidly in maximum degree, improves the effective percentage of ointment absorption.

Description

A kind of swelling and pain relieving ointment and preparation method thereof
Technical field
The present invention relates to the technical fields of Chinese medicine preparation more particularly to a kind of swelling and pain relieving ointment and preparation method thereof.
Background technique
It sprains and refers to the indirect violences such as rotation, drawing or the fierce and uncoordinated contraction of muscle, joint is made to occur to surpass suddenly Out when the activity of physiological range, the tissues such as muscle, tendon, ligament, fascia and joint capsule is caused to generate tearing, fracture or displacement Deng, with the purple green injury disease mainly to show of local swelling, pain, limitation of activity and color of the leather, the usually acute strain waited Commonly soft tissue injury and ligament injury.
Currently, being directed to the treating method that acute strain is dampened is to smear the ointment of swelling and pain relieving, now use on the market The swelling and pain relieving ointment for acute muscles and bones bruise the main problems are as follows: the first, most external-applied ointments are Chinese herbal medicine is by simply morcelling blending processing, and thus it is more to contain impurity component for the ointment, it is few to can absorb effective component, and to skin The irritation of skin is strong, easily causes allergy;The second, in the ointment of part contain anti-inflammatory analgetic class Western medicine chemical component, side effect compared with It is more;There is storage, carried and used the inconveniences such as process in third, most external-applied ointments using half solidification liquid shape, It must often dressing to maintain curative effect, be restricted for needing long period fixed position to use;4th, most The efficient functional of external-applied ointment is irregular, it is difficult to timely treatment is played, the present invention is directed to acute muscles and bones bruise as a result, It is rapid to propose a kind of swelling and pain relieving, it is not easy to allergy and the swelling and pain relieving ointment easy to carry using storage.
Summary of the invention
It is an object of the invention to aiming at the deficiencies in the prior art, provide a kind of swelling and pain relieving ointment and its preparation Method, preparation process is easy, low production cost, and the prepared swelling and pain relieving ointment come out has significant activating microcirculation and removing stasis medicinal, temperature It through dredging collateral and the effect of swelling and pain relieving, effectively treats that all kinds of joints are acute, habitual strain, can fast and effeciently release and turn round the wounded Pain, and can be used for fast and effective healing of the sportsman because of training and competition acute sprain.
To achieve this purpose, the present invention adopts the following technical scheme:
A kind of swelling and pain relieving ointment, in parts by weight, comprising: 3-6 parts of Groomwell root oil, 2-7 parts of thickening agent and plaster of paris 10-15 Part.
For deficiency existing for existing swelling and pain relieving ointment, it is main that swelling and pain relieving ointment of the invention, which is used with Groomwell root oil, Constituent, using thickening agent and the plaster of paris as auxiliary material, the impurity component contained is few, and the pharmacological property of constituent is mild, to skin Irritation and side effect are less, the mutually matched effect of each component drug effect, have subsiding swelling and resolving stagnation, expelling wind and clearing away cold, clearing and activating the channels and collaterals, disappear Inflammation analgesic and the effect of strengthen muscles and bones, swelling and pain relieving ointment play detumescence and only especially in the strain of acute muscles and bones or contusion Pain acts on significant in efficacy, it is not easy to which allergy, being directed to traumatic injury, blood stasis and swelling pain, all pains of muscles and bones and arthralgia has well Therapeutic effect is free of any poisonous and harmful element, both safe and effective, which has convenient for absorbing, user Just, the advantages that duration of efficacy is long, low in cost, few side effects, quickly effective and significant in efficacy.
It is further illustrated, the Groomwell root oil is that filtering obtains Asian puccoon after frying in vegetable oil.
It is further illustrated, the thickening agent is yellow petroleum jelly and/or solid paraffin.Yellow petroleum jelly is faint yellow or yellow Color uniformly soft paste, also known as soft paraffin, it is odorless or almost odorless, there is soapy feeling with skin contact, there is certain wire drawing Property, chemical property stablize, can with most drugs compatibility, for prepare medicine ointment and skin sparing ointment raw material; The ingredient of cosmetic cream, face cream greasepaint etc.;The emulsifying ointment of textile industry lubrication silk goods, it can also be used to make cables manufacturing Additive use, mainly use its insulating effect;Use yellow petroleum jelly as auxiliary element, is suitably adjusted in addition to having Other than consistency and stretchability, when using ointment, skin wet can be kept, the skin histology of wound location is made to keep best shape State accelerates the repair ability of skin itself.
Solid paraffin is a kind of mineral wax, is from light lubricating oil fractions cold press or the cured cream of solvent dewaxing gained, through sweating Or the hydrocarbon solid obtained after solvent deoiling, main component are C18-C30 linear paraffins, also contain isoparaffin, cycloalkane and few Aromatic hydrocarbons is measured, can be used for manufacturing rubber product, paraffin paper wax crayon, food and drug component etc., adjusts medicine by adjusting solid paraffin The consistency of cream, in order to use smearing ointment.
Preferably, in parts by weight, the yellow petroleum jelly is 1-4 parts, and the solid paraffin is 1-3 parts.Using upper The yellow petroleum jelly and solid paraffin for stating number range are the viscosity that ointment is adjusted as suitable proportion, allow ointment It can be formulated into required solid-state congealed fat shape, use and carry in order to which user smear, while ointment is easy by people Body skin is absorbed, and the drug effect efficiency of ointment is improved.
Preferably, in parts by weight, the Groomwell root oil is 4.5 parts, the yellow petroleum jelly is 2.5 parts, the solid Paraffin is 0.75 part, the plaster of paris is 12.5 parts;The above group of optimum formula component for being divided into swelling and pain relieving ointment of the invention, Using the recipe ingredient, the collaboration and complementation of each component drug effect can be farthest played, drug action is stronger, treatment effect Fruit is more significant;Especially for playing detumescence in the strain of acute muscles and bones or contusion and analgesic effect curative effect is more significant.
The following are the specific drug effects of main component in swelling and pain relieving ointment:
Asian puccoon: it is bitter, it trembles with fear;Enter percardium, Liver Channel;Cool blood, heat clearing and blood circulation promoting, promoting eruption of detoxifying;Macula, damp and hot Huang are warmed for treating Subcutaneous ulcer, purpura, hematemesis hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, large carbuncle;Belong to comfrey Asian puccoon (gromwell root) With the root of lithospermum euchromum Royle (radix macrotomiae), shikonin extract can inhibit staphylococcus aureus, Bacterium prodigiosum, pyogenic baeceria, Escherichia coli Deng, and epithelial growth can be accelerated, promote local trauma more and and anti-inflammatory effect.
The Naphthaquinone Pigments contained in modern pharmacological research Asian puccoon have good antibacterial, the anti-inflammatory work for promoting wound healing With, and the benzoquinones and phenol contained in Asian puccoon has good analgesic effect;Its brilliant repair ability has east lavender Title, there is brilliant antiallergic sense, take off redness, the function of activation epidermal cell metabolism, and there is antibacterial action, while there is purple Grass has the effect of significant anti-acne and anti-inflammatory, there is very big cosmetic values, and the scope of application of Comfrey Balm is very wide, is located at skin On minor cut or wound, can nearly all apply Comfrey Balm make it restore, seem accidentally fall scratch, by knife incised wound, by hot water It scalds, the dry skin that is cold cracking etc., functional and practicability has its comparable effect.
The following are auxiliary elements in swelling and pain relieving ointment specifically to act on:
The plaster of paris: the plaster of paris be gypsum is carried out it is fumed made of, though the raw, plaster of paris is jljl, effect is obvious Difference, gypsum take orally more, and the plaster of paris is mainly external application, are mainly used for hygroscopic expelling pus and promoting granulation etc., and the plaster of paris has condensation hard Change fast, there is micro-expansibility, porosity is big and plasticity is good, can be used as in grit, paper filler, gas dryer and Plaster bandage medically.
The gypsum is added as a result, in ointment, is had effects that cohesion is hardened, is improved the hardness of ointment, reduces ointment Mobility use and carry storage in order to which user smear, together so that ointment is turned into required solid-state congealed fat shape When facilitate ointment and be steadily sticky on the positions such as affected part, do not need that frequent dressing is also sustainable to maintain effective curative effect, improve The drug effect efficiency of ointment, so that ointment has storage time long, easy to carry, it is special using easy and duration of efficacy length etc. Point.
Vegetable oil: vegetable oil is peanut oil, yellowish transparent, mild-natured, relax bowel and defecation, and external application acupoint injection therapy controls enteritis etc., institute Vegetable oil high temperature resistant is stated, deep fried foodstuff is suitable for.By using vegetable oil the main component in the Asian puccoon in ointment ingredient into Row frying plays mixing the major pharmaceutical component of Asian puccoon and be immersed in so that most effective component all blasts in Asian puccoon In vegetable oil, obtain preliminary Groomwell root oil, in order to the allotment of subsequent preparation Asian puccoon ointment, and vegetable oil have it is faint antibacterial Effect, is conducive to extend the storage time and service life of ointment.
Preferably, the swelling and pain relieving ointment is in solid-state congealed fat shape.Due to most external-applied ointments half solidification liquid shape, storage Deposit, carry, using there is inconvenience, it is necessary to frequent dressing to maintain curative effect, for need long period fixed position use by To limitation.According to patient comfort's degree and the demand used, the present invention is designed as in solid-state congealed fat shape the balm, should Ointment carries and storage is convenient, and when use only need to simply smear row wrapping again in affected part, facilitate ointment steadily glue it is glutinous On the positions such as affected part, length of holding time does not have to frequent dressing, without irritation or sense of discomfort, it is not easy to allergy, to guarantee to suffer from The experience of person's comfort level.
A kind of preparation method of swelling and pain relieving ointment, includes the following steps:
(1) in parts by weight, the progress of 3-6 parts of addition vegetable oil of 0.2-1 parts of Asian puccoon is fried, filtering obtains Groomwell root oil;
(2) it is added yellow petroleum jelly 1-4 parts to the Groomwell root oil of step (1), 1-3 parts of solid paraffin are dissolved, and are then added 10-15 parts of the plaster of paris are stirred until semi-solid state, place, obtain balm.
The component of preparation method of the invention is scientific and reasonable, has no toxic side effect few, is formulated mild non-stimulated, the infant of safety And at can be used per capita;Production method is easy, and being in can be operated, and is not required to addition preservative, a small amount of to make, and is put using safe The heart;Swelling and pain relieving ointment of the invention not only has sterilizing and itch-relieving, swelling and pain relieving, helps the medical effects such as wound healing, also has There is the effect of whitening and skin-protecting, plays significant swelling and pain relieving effect in particular for what the strain of acute muscles and bones was dampened.
Preferably, the deep-fat frying time in the step (1) is 10-20min.The Chinese medicinal material overwhelming majority is dry product, dry And be of close texture, effective component, which has crystallized or shaped, to be deposited in into the cell, and effective medicine point is not easy to ooze out, and uses oil using directly getting angry 10-20min is fried, the effective component inside medicinal material can be made directly quickly to overflow, raising prepares the efficiency of Groomwell root oil, and drug is treated Effect is obvious, therefore, Asian puccoon vegetable oil frying 10-20min, is conducive to the allotment of postorder ointment, improve ointment it is effective at The drug effect content divided, enhances the effect of the swelling and pain relieving of ointment.
Preferably, the standing time in the step (2) is 3-7 days.It is stirred by the way that the plaster of paris is added until half is solid Body state, accelerates the setting rate of ointment, then places a couple of days, just obtains the balm.Use standing time for 3-7 days, ointment is made to obtain abundant coagulation forming to solid-state congealed fat state.If standing time is too short, the plaster of paris does not have enough time adjusting The hardness of the ointment of fluidised form shape causes ointment to be difficult into required form, if standing time is longer, is more conducive to improve ointment Viscosity and hardness so that entire ointment it is exuberant the ingredient of Asian puccoon, such ointment be just easier to play function itself and treatment And other effects, it is smeared convenient for user.
It is further illustrated, a kind of above-mentioned swelling and pain relieving ointment is used to treat muscles and bones bruise.Medicine of the invention Cream uses Asian puccoon Chinese medicine and carries out that ointment is made, and ointment has dispelling wind and removing obstruction in the meridians, activates blood and relax tendons, the swelling and pain relieving function anti-inflammatory with sterilization Effect also can have good effect for the performance of a variety of diseases simultaneously, particularly, for the acute outside such as muscles and bones bruise Injury is dispelled because of symptoms such as arthralgia and myalgias caused by spraining or dampening, from there through above-mentioned group with reaching the fast treatment mesh of curative effect The ointment of point preparation, the effects of activating microcirculation and removing stasis medicinal, warming and activating meridian and swelling and pain relieving, is stronger, and the speed for guaranteeing that component drug effect plays is mutual Cooperation plays component drug effect maximum, effective point of balm of absorptivity is improved, so that ointment reaches best The therapeutic effect of swelling and pain relieving.
Swelling and pain relieving ointment of the invention is used using Groomwell root oil as main constituents, supplemented by thickening agent and the plaster of paris Material has the effects that stronger activating microcirculation and removing stasis medicinal, anti-inflammatory analgetic, warming and activating meridian and cold dispelling by the effect of each component coordinated, The impurity component contained is few, and the pharmacological property of constituent is mild, less to skin irritation and side effect, can be widely applied to treat The pains of injury such as muscles and bones joint, especially for detumescence is played in the strain of acute muscles and bones or contusion and analgesic effect is significant in efficacy, simultaneously With low in cost, to carry easy to use, safe, few side effects, duration of efficacy long, quickly effective and significant in efficacy etc. Advantage alleviates rapidly the pain of the sick and wounded process of muscles and bones by above-mentioned ointment in maximum degree, improves ointment absorption Effective percentage, meet the market demand of traditional Chinese medicine industry.
The manufacturing method of swelling and pain relieving ointment of the invention can fry Asian puccoon into Groomwell root oil, and thickening agent and the plaster of paris is added It is deployed, is adjusted into the ointment of required solid-state congealed fat shape, operating method is simple, and it is low in cost, it is efficient and convenient, it can make Standby swelling and pain relieving ointment above-mentioned out.
Specific embodiment
The present invention program is described in detail below by some specific embodiments.Those skilled in the art should manage Solution, it is following to be embodied as preferred embodiment, only the present invention program is explained, and wherein might have to known skill The appropriate omission of art, those skilled in the art should understand the present invention in conjunction with the explanation of well-known technique and embodiment.
A kind of swelling and pain relieving ointment, in parts by weight, comprising: 3-6 parts of Groomwell root oil, 2-7 parts of thickening agent and the plaster of paris 10-15 parts.
For deficiency existing for existing swelling and pain relieving ointment, it is main that swelling and pain relieving ointment of the invention, which is used with Groomwell root oil, Constituent, using thickening agent and the plaster of paris as auxiliary material, the impurity component contained is few, and the pharmacological property of constituent is mild, to skin Irritation and side effect are less, the mutually matched effect of each component drug effect, have subsiding swelling and resolving stagnation, expelling wind and clearing away cold, clearing and activating the channels and collaterals, disappear Inflammation analgesic and the effect of strengthen muscles and bones, swelling and pain relieving ointment play detumescence and only especially in the strain of acute muscles and bones or contusion Pain acts on significant in efficacy, it is not easy to which allergy, being directed to traumatic injury, blood stasis and swelling pain, all pains of muscles and bones and arthralgia has well Therapeutic effect is free of any poisonous and harmful element, both safe and effective, which has convenient for absorbing, user Just, the advantages that duration of efficacy is long, low in cost, few side effects, quickly effective and significant in efficacy.
It is further illustrated, the Groomwell root oil is that filtering obtains Asian puccoon after frying in vegetable oil.
It is further illustrated, the thickening agent is yellow petroleum jelly and/or solid paraffin.Yellow petroleum jelly is faint yellow or yellow Color uniformly soft paste, also known as soft paraffin, it is odorless or almost odorless, there is soapy feeling with skin contact, there is certain wire drawing Property, chemical property stablize, can with most drugs compatibility, for prepare medicine ointment and skin sparing ointment raw material; The ingredient of cosmetic cream, face cream greasepaint etc.;The emulsifying ointment of textile industry lubrication silk goods, it can also be used to make cables manufacturing Additive use, mainly use its insulating effect;Use yellow petroleum jelly as auxiliary element, is suitably adjusted in addition to having Other than consistency and stretchability, when using ointment, skin wet can be kept, the skin histology of wound location is made to keep best shape State accelerates the repair ability of skin itself.
Solid paraffin is a kind of mineral wax, is from light lubricating oil fractions cold press or the cured cream of solvent dewaxing gained, through sweating Or the hydrocarbon solid obtained after solvent deoiling, main component are C18-C30 linear paraffins, also contain isoparaffin, cycloalkane and few Aromatic hydrocarbons is measured, can be used for manufacturing rubber product, paraffin paper wax crayon, food and drug component etc., adjusts medicine by adjusting solid paraffin The consistency of cream, in order to use smearing ointment.
Preferably, in parts by weight, the yellow petroleum jelly is 1-4 parts, and the solid paraffin is 1-3 parts.Using upper The yellow petroleum jelly and solid paraffin for stating number range are the viscosity that ointment is adjusted as suitable proportion, allow ointment It can be formulated into required solid-state congealed fat shape, use and carry in order to which user smear, while ointment is easy by people Body skin is absorbed, and the drug effect efficiency of ointment is improved.
Preferably, in parts by weight, the Groomwell root oil is 4.5 parts, the yellow petroleum jelly is 2.5 parts, the solid Paraffin is 0.75 part, the plaster of paris is 12.5 parts;The above group of optimum formula component for being divided into swelling and pain relieving ointment of the invention, Using the recipe ingredient, the collaboration and complementation of each component drug effect can be farthest played, drug action is stronger, treatment effect Fruit is more significant;Especially for playing detumescence in the strain of acute muscles and bones or contusion and analgesic effect curative effect is more significant.It is above-mentioned Explain the drug effect or effect of each component in detail, thus just no longer burden illustrates one by one here.
Preferably, the swelling and pain relieving ointment is in solid-state congealed fat shape.Due to most external-applied ointments half solidification liquid shape, storage Deposit, carry, using there is inconvenience, it is necessary to frequent dressing to maintain curative effect, for need long period fixed position use by To limitation.According to patient comfort's degree and the demand used, the present invention is designed as in solid-state congealed fat shape the balm, should Ointment carries and storage is convenient, and when use only need to simply smear row wrapping again in affected part, facilitate ointment steadily glue it is glutinous On the positions such as affected part, length of holding time does not have to frequent dressing, without irritation or sense of discomfort, it is not easy to allergy, to guarantee to suffer from The experience of person's comfort level.
A kind of preparation method of swelling and pain relieving ointment, includes the following steps:
(1) in parts by weight, the progress of 3-6 parts of addition vegetable oil of 0.2-1 parts of Asian puccoon is fried, filtering obtains Groomwell root oil;
(2) it is added yellow petroleum jelly 1-4 parts to the Groomwell root oil of step (1), 1-3 parts of solid paraffin are dissolved, and are then added 10-15 parts of the plaster of paris are stirred until semi-solid state, place, obtain balm.
The component of preparation method of the invention is scientific and reasonable, has no toxic side effect few, is formulated mild non-stimulated, the infant of safety And at can be used per capita;Production method is easy, and being in can be operated, and is not required to addition preservative, a small amount of to make, and is put using safe The heart;Swelling and pain relieving ointment of the invention not only has sterilizing and itch-relieving, swelling and pain relieving, helps the medical effects such as wound healing, also has There is the effect of whitening and skin-protecting, plays significant swelling and pain relieving effect in particular for what the strain of acute muscles and bones was dampened.
Preferably, the deep-fat frying time in the step (1) is 10-20min.The Chinese medicinal material overwhelming majority is dry product, dry And be of close texture, effective component, which has crystallized or shaped, to be deposited in into the cell, and effective medicine point is not easy to ooze out, and uses oil using directly getting angry 10-20min is fried, the effective component inside medicinal material can be made directly quickly to overflow, raising prepares the efficiency of Groomwell root oil, and drug is treated Effect is obvious, therefore, Asian puccoon vegetable oil frying 10-20min, is conducive to the allotment of postorder ointment, improve ointment it is effective at The drug effect content divided, enhances the effect of the swelling and pain relieving of ointment.
Preferably, the standing time in the step (2) is 3-7 days.It is stirred by the way that the plaster of paris is added until half is solid Body state, accelerates the setting rate of ointment, then places a couple of days, just obtains the balm.Use standing time for 3-7 days, ointment is made to obtain abundant coagulation forming to solid-state congealed fat state.If standing time is too short, the plaster of paris does not have enough time adjusting The hardness of the ointment of fluidised form shape causes ointment to be difficult into required form, if standing time is longer, is more conducive to improve ointment Viscosity and hardness so that entire ointment it is exuberant the ingredient of Asian puccoon, such ointment be just easier to play function itself and treatment And other effects, it is smeared convenient for user.
It is further illustrated, a kind of above-mentioned swelling and pain relieving ointment is used to treat muscles and bones bruise.Medicine of the invention Cream uses Asian puccoon Chinese medicine and carries out that ointment is made, and ointment has dispelling wind and removing obstruction in the meridians, activates blood and relax tendons, the swelling and pain relieving function anti-inflammatory with sterilization Effect also can have good effect for the performance of a variety of diseases simultaneously, particularly, for the acute outside such as muscles and bones bruise Injury is dispelled because of symptoms such as arthralgia and myalgias caused by spraining or dampening, from there through above-mentioned group with reaching the fast treatment mesh of curative effect The ointment of point preparation, the effects of activating microcirculation and removing stasis medicinal, warming and activating meridian and swelling and pain relieving, is stronger, and the speed for guaranteeing that component drug effect plays is mutual Cooperation plays component drug effect maximum, effective point of balm of absorptivity is improved, so that ointment reaches best The therapeutic effect of swelling and pain relieving.
The present invention is described in detail combined with specific embodiments below.
Embodiment 1:
0.2 part of Asian puccoon, 3 parts of addition vegetable oil progress frying 20min, filtering obtains Groomwell root oil, and Xiang Suoshu Groomwell root oil is added yellow 1 part of vaseline, 1 part of solid paraffin is dissolved, and is then added 10 parts of the plaster of paris and is stirred until semi-solid state, places 7 It, obtains balm.
Embodiment 2:
1 part of Asian puccoon, 6 parts of addition vegetable oil progress frying 20min, filtering obtains Groomwell root oil, and Xiang Suoshu Groomwell root oil is added yellow all 4 parts of intellectual circle, 3 parts of solid paraffin are dissolved, and are then added 15 parts of the plaster of paris and are stirred until semi-solid state, place 7 days, Obtain balm.
Embodiment 3:
0.8 part of Asian puccoon, 3 parts of addition vegetable oil progress frying 20min, filtering obtains Groomwell root oil, and Xiang Suoshu Groomwell root oil is added yellow 1.5 parts of vaseline, 3.5 parts of solid paraffin are dissolved, and are then added 13.5 parts of the plaster of paris and are stirred until semi-solid state, It places 7 days, obtains balm.
Embodiment 4:
0.4 part of Asian puccoon, 5 parts of addition vegetable oil progress frying 20min, filtering obtains Groomwell root oil, and Xiang Suoshu Groomwell root oil is added yellow 3 parts of vaseline, 2 parts of solid paraffin are dissolved, and are then added 13 parts of the plaster of paris and are stirred until semi-solid state, place 7 It, obtains balm.
Embodiment 5:
0.6 part of Asian puccoon, 4 parts of addition vegetable oil progress frying 20min, filtering obtains Groomwell root oil, and Xiang Suoshu Groomwell root oil is added yellow 2 parts of vaseline, 1.5 parts of solid paraffin are dissolved, and are then added 12 parts of the plaster of paris and are stirred until semi-solid state, place 7 days, obtain balm.
Embodiment 6:
0.5 part of Asian puccoon, 4.5 parts of addition vegetable oil progress frying 20min, filtering obtains Groomwell root oil, and Xiang Suoshu Groomwell root oil is added 2.5 parts of yellow petroleum jelly, 0.75 part of solid paraffin is dissolved, and is then added 12.5 parts of the plaster of paris and is stirred until semi-solid State places 7 days, obtains balm.
Comparative example 1:
0.5 part of Asian puccoon, 4.5 parts of addition vegetable oil progress frying 20min, filtering obtains Groomwell root oil, and Xiang Suoshu Groomwell root oil is added 2.5 parts of yellow petroleum jelly are dissolved, and are then added 12.5 parts of the plaster of paris and are stirred until semi-solid state, place 7 days, obtain Compare balm.
Note: the product is without addition solid paraffin component.
Comparative example 2:
0.5 part of Asian puccoon, 4.5 parts of addition vegetable oil progress frying 20min, filtering obtains Groomwell root oil, and Xiang Suoshu Groomwell root oil is added 0.75 part of solid paraffin is dissolved, and is then added 12.5 parts of the plaster of paris and is stirred until semi-solid state, places 7 days, obtain To comparison balm.
Note: the product is without addition yellow petroleum jelly component.
Comparative example 3:
0.5 part of Asian puccoon, 4.5 parts of addition vegetable oil progress frying 20min, filtering obtains Groomwell root oil, and Xiang Suoshu Groomwell root oil is added 2.5 parts of yellow petroleum jelly, 0.75 part of solid paraffin carries out dissolution stirring, places 7 days, obtains comparison balm.
Note: the product is without addition plaster of paris component.
Effect proof property test is carried out for the balm of each embodiment and comparative example preparation.
Clinical testing data: choosing the strain patient of Fushan City, Guangdong Province 130 and carry out clinical observation treatment, wherein male 65 Example, female 65, the age 11-58 years old, average age 37 years old.In 130 strain patients, lumbar strain patient 20, ankle sprain Patient 20, knee sprain patient 18, shoulder sprains patient 16, wrist sprains patient 18, ancon sprains patient 18, Hip sprains patient 20;The above patient symptom has one of following or two or more: sprain position local swelling, severe pain, Limitation of activity, joint subcutaneous extvavasated blood form hemotoncus.
Above 130 patient's stochastic averaginas are divided into Liang Ge treatment group, each treatment group 65, wherein treatment group 1 uses Embodiment 1-6 preparation balm treated, treatment group 2 using comparative example 1-3 preparation comparison balm into Row treatment.
The application method for the Chinese materia medica preparation that treatment of the invention is sprained: it will sprain after position cleans up, and use medical cotton stick It dips balm of the invention to smear, a natural gift are sooner or later each to clean primary, three days as a treatment course;Then proceed in experiment Behind third day, scored state (including spraining position symptom improvement situation, adverse reaction etc.) (scoring mark after recording its treatment 1) the corresponding table of standard see the table below, while institute is counted using the number of ointment and the number of recovery from illness to the recovery from illness of each patient, record With calculating cure rate, obtained experimental result see the table below 2- table 3.
1 standards of grading of table correspond to table
The test of 2 embodiment 1-6 therapeutic effect of table
As seen from the results in Table 1:
(1) pass through embodiment 1-6 and compare the ointment component that can be seen that embodiment 6 and dosage for optimum formula, in embodiment 6 That sprains the said components of the scoring score ratio embodiment 1-5 of state after the treatment of patient wants high, and the number for treating healing wants more, Best for the curative effect of strain, other components numerical value corresponding in value range has corresponding variation, and patient is equal after three days The therapeutic effect that can reach recovery from illness, has not observed adverse reaction.
The test of 3 comparative example 1-3 therapeutic effect of table
As seen from the results in Table 3:
(1) it is compared by comparative example 1-3 as can be seen that not adding yellow petroleum jelly, solid when other components are centainly constant Paraffin and the plaster of paris a certain component therein, the scoring score of state is not high after the treatment of patient, belongs to patients with mild and recovery from illness Between patient, treatment number is in medium level, the therapeutic effect that patient has some of the staff not reach recovery from illness after test three days.
From the result of table 2 and 3:
(1) by embodiment 6 and comparative example 1-3 comparison as can be seen that not added yellow all when other components are centainly constant Intellectual circle, solid paraffin and the plaster of paris a certain component therein, the scoring score ratio embodiment 6 for spraining state after the treatment of patient are complete Addition said components in portion's want low, and treatment number will be lacked, the treatment that patient has some of the staff not reach recovery from illness after test three days Effect.
In conclusion swelling and pain relieving ointment of the invention is used using Asian puccoon as main constituents, with thickening agent, the plaster of paris It is auxiliary material with vegetable oil, there is stronger activating microcirculation and removing stasis medicinal, anti-inflammatory analgetic, warming and activating meridian by the effect of each component coordinated and dissipate The effects of cold, can be widely applied to the pains of injury such as treatment muscles and bones joint, effectively treat that all kinds of joints are acute, habitual strain, can be fast Speed effectively releases the pain for turning round the wounded, and can be used for fast and effective healing of the sportsman because of training and competition acute sprain, passes through Above-mentioned ointment alleviates rapidly the pain of the sick and wounded process of muscles and bones in maximum degree, improves the effective percentage of ointment absorption, The market demand of traditional Chinese medicine industry is met, market prospects are considerable.
The above description of the embodiments is intended to facilitate ordinary skill in the art to understand and use the invention. Person skilled in the art obviously easily can make various modifications to these embodiments, and described herein general Principle is applied in other embodiments without having to go through creative labor.Therefore, the present invention is not limited to the above embodiments, ability Field technique personnel announcement according to the present invention, improvement and modification made without departing from the scope of the present invention all should be of the invention Within protection scope.

Claims (10)

1. a kind of swelling and pain relieving ointment, which is characterized in that in parts by weight, comprising: 3-6 parts of Groomwell root oil, 2-7 parts of thickening agent With 10-15 parts of the plaster of paris.
2. a kind of swelling and pain relieving ointment according to claim 1, which is characterized in that the Groomwell root oil is Asian puccoon in vegetable oil Filtering obtains after middle frying.
3. a kind of swelling and pain relieving ointment according to claim 1, which is characterized in that the thickening agent be yellow petroleum jelly and/ Or solid paraffin.
4. a kind of swelling and pain relieving ointment according to claim 1, which is characterized in that in parts by weight, the Huang is all Intellectual circle is 1-4 parts, and the solid paraffin is 1-3 parts.
5. a kind of swelling and pain relieving ointment according to claim 4, which is characterized in that in parts by weight, the Asian puccoon Oil is 4.5 parts, the yellow petroleum jelly is 2.5 parts, the solid paraffin is 0.75 part, the plaster of paris is 12.5 parts.
6. a kind of swelling and pain relieving ointment according to claim 1, which is characterized in that the swelling and pain relieving ointment is solidifying in solid-state Smectic.
7. a kind of preparation method of swelling and pain relieving ointment, which comprises the steps of:
(1) in parts by weight, the progress of 3-6 parts of addition vegetable oil of 0.2-1 parts of Asian puccoon is fried, filtering obtains Groomwell root oil;
(2) it is added yellow petroleum jelly 1-4 parts to the Groomwell root oil of step (1), 1-3 parts of solid paraffin are dissolved, and are then added 10-15 parts of plaster of paris stirrings place until semi-solid state, obtain balm.
8. a kind of preparation method of swelling and pain relieving ointment according to claim 7, which is characterized in that in the step (1) Deep-fat frying time be 10-20min.
9. a kind of preparation method of swelling and pain relieving ointment according to claim 7, which is characterized in that in the step (2) Standing time be 3-7 days.
10. being used to treat muscles and bones bruise for a kind of swelling and pain relieving ointment as described in any one of claim 1-6.
CN201710715210.2A 2017-08-20 2017-08-20 A kind of swelling and pain relieving ointment and preparation method thereof Withdrawn CN109419837A (en)

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Application publication date: 20190305