CN109963595B - 用于治疗神经退行性疾病的含有大麻素的复合混合物 - Google Patents

用于治疗神经退行性疾病的含有大麻素的复合混合物 Download PDF

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CN109963595B
CN109963595B CN201780071100.5A CN201780071100A CN109963595B CN 109963595 B CN109963595 B CN 109963595B CN 201780071100 A CN201780071100 A CN 201780071100A CN 109963595 B CN109963595 B CN 109963595B
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active ingredient
pharmaceutical composition
cannabinoids
administration
cannabinoid
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CN109963595A (zh
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A·斯马尔-霍华德
H·特纳
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Growblox Life Sciences LLC
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Growblox Life Sciences LLC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/348—Cannabaceae
    • A61K36/3482—Cannabis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
CN201780071100.5A 2016-10-11 2017-10-10 用于治疗神经退行性疾病的含有大麻素的复合混合物 Active CN109963595B (zh)

Priority Applications (1)

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CN202310039015.8A CN115887440A (zh) 2016-10-11 2017-10-10 用于治疗神经退行性疾病的含有大麻素的复合混合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662406764P 2016-10-11 2016-10-11
US62/406,764 2016-10-11
PCT/US2017/055989 WO2018071452A1 (en) 2016-10-11 2017-10-10 Cannabinoid-containing complex mixtures for the treatment of neurodegenerative diseases

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CN202310039015.8A Division CN115887440A (zh) 2016-10-11 2017-10-10 用于治疗神经退行性疾病的含有大麻素的复合混合物

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CN109963595B true CN109963595B (zh) 2023-02-03

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CN202310039015.8A Pending CN115887440A (zh) 2016-10-11 2017-10-10 用于治疗神经退行性疾病的含有大麻素的复合混合物

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US (3) US10653640B2 (https=)
EP (1) EP3525823B1 (https=)
JP (2) JP7225103B2 (https=)
CN (2) CN109963595B (https=)
AU (3) AU2017344040A1 (https=)
CA (1) CA3039413A1 (https=)
IL (1) IL265902B2 (https=)
WO (1) WO2018071452A1 (https=)

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JP2021524465A (ja) 2018-05-22 2021-09-13 ジービーエス グローバル バイオファーマ，インコーポレイテッド Ｔｒｐｖ１モジュレーションに使用するためのカンナビノイド及び／又はテルペン
CA3119729A1 (en) 2018-10-10 2020-04-16 Treehouse Biotech, Inc. Synthesis of cannabigerol
EP3902538A4 (en) * 2018-12-29 2023-01-18 Buzzelet Development And Technologies Ltd ISOLATED OR SYNTHETIC CANNABINOID COMPOSITIONS WITH SELECTED TERPEN BLEND AND METHODS OF USE THEREOF
SG11202111809XA (en) * 2019-04-24 2021-11-29 Inmed Pharmaceuticals Inc Compositions and methods for use of cannabinoids for neuroprotection
US20200405657A1 (en) * 2019-06-28 2020-12-31 Gbs Global Biopharma, Inc. Treatment of pain using allosteric modulator of trpv1
US12576093B2 (en) 2019-07-17 2026-03-17 Mannkind Corporation Pharmaceutical composition for subcutaneous administration
US12409131B2 (en) 2019-10-03 2025-09-09 Pike Therapeutics Usa, Inc. Transdermal delivery of dronabinol
CN114650809A (zh) 2019-10-03 2022-06-21 斯塔顿治疗公司 屈大麻酚的透皮递送
CN113694049B (zh) * 2020-05-21 2022-11-22 汉义生物科技（北京）有限公司 大麻素类化合物及其在治疗帕金森症中的应用
MX2023000314A (es) * 2020-08-17 2023-02-22 Pike Therapeutics Inc Formulaciones farmaceuticas transdermicas de cannabinoides.
EP4200276A2 (en) * 2020-08-18 2023-06-28 GBS Global Biopharma, Inc. Cannabinoid-containing complex mixtures for the treatment of cytokine release syndrome while preserving key anti-viral immune reactions
ES2962999T3 (es) 2021-07-30 2024-03-22 Cannamedical Pharma Gmbh Parche transmucoso que comprende un cannabinoide y/o un opiáceo
CN113368086B (zh) * 2021-08-11 2021-12-03 龙麻(上海)医药研发有限责任公司 一种大麻素组合物及其在制备治疗帕金森、阿尔茨海默等神经退行性疾病的药物中的应用
EP4408404A4 (en) * 2021-09-28 2025-10-29 Gbs Global Biopharma Inc Formulations containing cannabinoids for Parkinsonian movement disorders
US20240261302A1 (en) * 2023-01-04 2024-08-08 Florascience Inc. Methods of treating neurodegenerative diseases or conditions
WO2024160792A1 (en) 2023-01-30 2024-08-08 Cannamedical Pharma Gmbh Improved transmucosal patch comprising a cannabinoid and/or an opioid

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Also Published As

Publication number Publication date
IL265902B2 (en) 2024-04-01
EP3525823B1 (en) 2024-04-24
CN115887440A (zh) 2023-04-04
CN109963595A (zh) 2019-07-02
US20250108016A1 (en) 2025-04-03
US20180098948A1 (en) 2018-04-12
IL265902B1 (en) 2023-12-01
AU2023222872A1 (en) 2023-09-21
AU2025213702A1 (en) 2025-09-04
JP2023058599A (ja) 2023-04-25
CA3039413A1 (en) 2018-04-19
WO2018071452A1 (en) 2018-04-19
IL265902A (en) 2019-06-30
JP7225103B2 (ja) 2023-02-20
US20200338017A1 (en) 2020-10-29
JP2019530751A (ja) 2019-10-24
US10653640B2 (en) 2020-05-19
AU2017344040A1 (en) 2019-04-18
US11980592B2 (en) 2024-05-14
EP3525823A1 (en) 2019-08-21

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