CN109906222B - 减少p-tau并且改善认知的变构促肾上腺皮质激素释放因子受体1(crfr1)拮抗剂 - Google Patents

减少p-tau并且改善认知的变构促肾上腺皮质激素释放因子受体1(crfr1)拮抗剂 Download PDF

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CN109906222B
CN109906222B CN201780067124.3A CN201780067124A CN109906222B CN 109906222 B CN109906222 B CN 109906222B CN 201780067124 A CN201780067124 A CN 201780067124A CN 109906222 B CN109906222 B CN 109906222B
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compound
disease
alzheimer
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CN109906222A (zh
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M·P·阿拉姆
V·约翰
B·雅格辛斯卡
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University of California San Diego UCSD
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CN201780067124.3A 2016-09-07 2017-09-06 减少p-tau并且改善认知的变构促肾上腺皮质激素释放因子受体1(crfr1)拮抗剂 Active CN109906222B (zh)

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US201662384656P 2016-09-07 2016-09-07
US62/384,656 2016-09-07
PCT/US2017/050347 WO2018048953A1 (en) 2016-09-07 2017-09-06 Allosteric corticotropin-releasing factor receptor 1 (crfr1) antagonists that decrease p-tau and improve cognition

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CN109906222A CN109906222A (zh) 2019-06-18
CN109906222B true CN109906222B (zh) 2023-08-01

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US (1) US11077108B2 (https=)
EP (1) EP3510029B1 (https=)
JP (1) JP7187037B2 (https=)
KR (1) KR102571296B1 (https=)
CN (1) CN109906222B (https=)
AU (1) AU2017324942B2 (https=)
WO (1) WO2018048953A1 (https=)

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CN116832160A (zh) * 2023-03-15 2023-10-03 上海市宝山区吴淞中心医院 Aβ1-42在制备子痫前期治疗药物或诊断试剂盒中的用途
CN118121593B (zh) * 2024-02-26 2025-02-14 首都医科大学宣武医院 一种用于预防和/或治疗阿尔茨海默病的药物组合物及其用途

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AU2017324942B2 (en) 2022-01-27
US20190307747A1 (en) 2019-10-10
CA3039026A1 (en) 2018-03-15
KR102571296B1 (ko) 2023-08-28
JP7187037B2 (ja) 2022-12-12
KR20190057316A (ko) 2019-05-28
EP3510029B1 (en) 2025-11-05
AU2017324942A1 (en) 2019-04-18
CN109906222A (zh) 2019-06-18
WO2018048953A1 (en) 2018-03-15
JP2019526639A (ja) 2019-09-19
EP3510029A1 (en) 2019-07-17
US11077108B2 (en) 2021-08-03

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