CN109900688A - A kind of indicator paper block of the accurate positioning of urine detection - Google Patents
A kind of indicator paper block of the accurate positioning of urine detection Download PDFInfo
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- 238000001514 detection method Methods 0.000 title claims abstract description 83
- 210000002700 urine Anatomy 0.000 title claims abstract description 51
- 238000012360 testing method Methods 0.000 claims abstract description 24
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- 238000003780 insertion Methods 0.000 claims abstract description 5
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- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 6
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 claims description 6
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 claims description 6
- OBHRVMZSZIDDEK-UHFFFAOYSA-N urobilinogen Chemical compound CCC1=C(C)C(=O)NC1CC1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(CC3C(=C(CC)C(=O)N3)C)N2)CCC(O)=O)N1 OBHRVMZSZIDDEK-UHFFFAOYSA-N 0.000 claims description 6
- 230000004807 localization Effects 0.000 claims description 4
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 3
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 claims description 3
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- 235000010323 ascorbic acid Nutrition 0.000 claims description 3
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Abstract
The invention discloses a kind of indicator paper blocks of the accurate positioning of urine detection, it includes the strip thin substrate of test-paper, white；The strip thin substrate of white includes integrally formed rectangular panel portion and handle portion；Test-paper is located on rectangular panel portion；Test-paper equidistantly arranges small indicator paper block equipped with several；Rectangular panel portion is located at the outside of each small indicator paper block and is close to the position of small indicator paper block, be equipped with black outline border；The middle part of test-paper is equipped with an insertion indication wire in the width direction；The middle and lower part of test-paper is equipped with arrow prompt icon along its length, marks in the lower section of arrow prompt icon equipped with " This side up "；The edge of test-paper is equipped with rounding off；Indicator paper block accurate positioning, testing result accurate rate are high.
Description
Technical field
The present invention relates to medical fields, and in particular to a kind of indicator paper block of the accurate positioning of urine detection.
Background technique
Currently with the improvement of living standards with the transformation of life style, the disease incidence of chronic disease constantly increased, illness people
For group's quantity also growing, early screening and daily management for disease become family health care and sanitarian great difficulty
Topic；By increasing the reagent block of detection body many index in test strips, the health of human body can be relatively accurately judged
The screening monitoring of situation, diseases numerous for renal function, liver function, inflammation, diabetes etc. all has good clinical meaning；
The common method that urine detection is medical treatment detection is carried out using test paper, mainly by adding chemistry on reagent block
Secretory substance in reagent, with urine is chemically reacted, and color change is generated, the case where further according to reagent block color change and
Degree come judge the tie substance content in urine number, and then be used for the detection and judgement of disease；With convenient and efficient, nothing
Bitterly noninvasive, low in cost, simple operation and other advantages have become the primary selection of disorder in screening and routine testing；
Urine detection examination paper product is more currently on the market, mainly has single single test paper, double from product arrangement
Test paper etc. includes individual event, two, three, four, five, six, eight, ten, 11,12 from the point of view of detection project
Item, 13,14 urine detection test strips or test-paper；14 urine detection test paper currently on the market are mainly single
Row's arrangement, has the disadvantage that
(1) test strips length is too long, is easy to happen bending, fracture；
(2) deeper container is needed, otherwise urine is not enough to be completely soaked test paper；
(3) if needing longer slot using the automatic Testing index of detection device, it is unfavorable for the production processing of slot
With use；
(4) prompt information is few, and user experience is low.
The technology analyzed at present urine detection test paper is mainly: shooting image by camera, or passes through
Color sensor reads color value, then carries out analysis matching to image and color value, finds corresponding index content concn, matches phase
The doubtful illness answered and treatment recommendations etc..Image is shot using camera either smart phone, then carries out color identification
Method has the disadvantage that
(1) when detecting each time, the position of indicator paper block always has a small amount of variation, cannot be straight using the method for fixed position
It connects and is cut from image, easily occur cutting the situation of inaccuracy, cause indicator paper block imperfect, or be non-indicator paper block portion
Divide and be introduced into, so as to cause testing result inaccuracy；
(2) it according to the method for reducing crop box, easily leads to a large amount of useful pixel on indicator paper block and is wasted, keep color flat
The calculating of mean value is not accurate；
(3) it if obtaining indicator paper block using color segmentation method in the picture, is easy by camera colour cast, the interference of shade
And it malfunctions；
(4) if calculating the position of indicator paper block using sciagraphy, it is required that the indicator paper block of every a line all guarantees that high-precision is aligned,
A little offset all can cause arithmetic result incorrect；
(5) abnormal in the prevalence of different degrees of radial direction when using optical lens, especially fish eye lens shooting image
Become；At this point, the method failure of indicator paper block positioning is realized based on straight-line detection, gradient projection etc. in the picture；And due to test paper
The shift in position by a small margin of block, it is also difficult to expect the distortion amplitude of each indicator paper block.
Summary of the invention
In view of the defects and deficiencies of the prior art, the present invention intends to provide a kind of simple structure and reasonable design, make
With the indicator paper block localization method of convenient urine detection.
To achieve the above object, the technical solution adopted by the present invention is that: it include test-paper, white the thin base of strip
Plate；The strip thin substrate of white includes integrally formed rectangular panel portion and handle portion；Test-paper is located on rectangular panel portion；Test paper
On piece equidistantly arranges small indicator paper block equipped with several；Rectangular panel portion is located at the outside of each small indicator paper block and is close to small indicator paper block
Position, be equipped with black outline border；The middle part of test-paper is equipped with an insertion indication wire in the width direction；The middle and lower part of test-paper
It is equipped with arrow along its length and prompts icon, is marked in the lower section of arrow prompt icon equipped with " This side up "；The side of test-paper
Rounding off is equipped at angle；
Further, the test-paper is equipped with leucocyte reagent block, white reference color lump one, white reference color lump
Two, ascorbic acid reagent block, nitrite reagent block, pH value reagent block, ketoboidies reagent block, urinary calcium reagent block, urobilinogen examination
Agent block, occult blood reagent block, bilirubin reagent block, creatinine reagent block, protein reagent block, specific gravity of urine reagent block, glucose reagent
Block, microalbumin reagent block；
Further, the spacing between small indicator paper block is 2mm；The spacing on small indicator paper block and boundary is 4-6mm；Strip is thin
Substrate with a thickness of 0.5mm；The line thickness of black outline border is 0.5mm in strip thin substrate；Two neighboring black outline border it
Between spacing be 1mm；The width of handle portion is 20mm；Handle portion is equipped with patch；
The localization method of indicator paper block comprises the following steps:
One, indicator paper block is impregnated in urine 1-3 seconds, indicator paper block is then inserted into urine detection instrument；At the top of urine detection instrument
Camera shoot image；
Two, gray level image Img_gray is converted by color image Img_color, gray scale value calculating method has following three
Kind:
(1) gray value is obtained to tri- path computation average values of RGB；
(2) utilize weighted formula: Gray=R*0.299+G*0.587+B*0.114 calculates to obtain gray value；
(3) using the maximum value in RGB tri- values as gray value；
Three, setting indicator paper block detects binaryzation empirical value Th_strip；
Four, binaryzation is carried out to gray level image Img_gray, obtains foreground image Img_fore；
Five, indicator paper block outline border positions, and obtains indicator paper block area-of-interest figure Img_ROI；
Six, setting indicator paper block black outline border detects binaryzation empirical value Th_bound；
Seven, in conjunction with gray level image Img_gray and indicator paper block area-of-interest figure Img_ROI, binaryzation is carried out, before obtaining
Scape image Img_fore2, the specific method is as follows:
(1) foreground image Img_fore2 is identical as gray level image Img_gray size；
(2) 0 is set by each pixel brightness value of foreground image Img_fore2；
(3) each of gray level image Img_gray pixel is traversed, if the corresponding indicator paper block sense of the location of pixels
The brightness value of interest administrative division map Img_ROI is 0, then does not handle；Otherwise, if the pixel brightness value in gray level image Img_gray
Lower than threshold value Th_bound, then 255 are set by the respective pixel value brightness in foreground image Img_fore2, if being higher than threshold
Value Th_bound, then be set as 0；
Eight, in conjunction with color image Img_color and indicator paper block area-of-interest figure Img_ROI, detection obtains foreground image
Img_fore3, the specific method is as follows:
(1) foreground image Img_fore3 is identical as gray level image Img_gray size；
(2) 0 is set by each pixel brightness value of foreground image Img_fore3；
(3) each of color image Img_color pixel is traversed；If the corresponding Img_ROI of the location of pixels
The brightness value of figure is 0, then does not handle；Otherwise, if as long as RGB tri- of position pixel values in color image Img_color
There is one to be less than threshold value Th_bound, then sets 255 for the respective pixel value brightness in foreground image Img_fore3, unless
RGB tri- values are both greater than Th_bound, are just set as 0；
(4) by image or operation, carry out Img_fore2 and Img_fore3 to be fused to Img_fore4；
Nine, foreground picture Img_fore4 is traversed, carries out the connected domain detection of black outline border, the specific method is as follows:
(1) connected domain detects, if connected domain number is less than the quantity of small indicator paper block, algorithm is terminated in advance, and early warning mentions
Show that user detects again；
(2) connected domain inner void is filled；
(3) area of all connected domains is calculated；
(4) connected domain that area maximum quantity is equal to the quantity of small indicator paper block is extracted；If the area of these connected domains is all
Greater than empirical value Th_area_patch, then subsequent step is carried out；Otherwise, algorithm terminates in advance, early warning, prompts user again
Detection；
(5) these connected domains are directed to, the indicator paper block area-of-interest figure Img_ROI for obtaining each connected domain is calculated separately,
The specific method is as follows:
A, it is directed to i-th of connected domain, establishes indicator paper block area-of-interest figure Bound_ROI_i, the figure size and grayscale image
Picture Img_gray is consistent, and each pixel value of indicator paper block area-of-interest figure Bound_ROI_i is set as 0；
B, for each pixel inside i-th of connected domain, in corresponding position by indicator paper block area-of-interest figure
Pixel value in Bound_ROI_i is set as 255；
Ten, indicator paper block interior zone detection threshold value Th_bound_inner is set；
11, on the basis of indicator paper block area-of-interest figure Bound_ROI_i, the accurate area-of-interest of indicator paper block is obtained
Scheme Bound_ROI_fine_i, the specific method is as follows:
(1) the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block and the same size of gray level image Img_gray, often
One pixel brightness value is set as 0；
(2) traversing each of indicator paper block area-of-interest figure Bound_ROI_i image white pixel, i.e. brightness value is
255 pixel；
(3) if respective pixel in gray level image Img_gray, brightness value is higher than indicator paper block interior zone detection threshold
Value Th_bound_inner, then by the respective pixel brightness value in the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block
It is set as 255；Otherwise, if RGB tri- of position pixel values in color image Img_color, as long as there is one to be higher than examination
Paper block interior zone detection threshold value Th_bound_inner, also by the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block
In respective pixel brightness value be set as 255；It otherwise, will be in the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block
Respective pixel brightness value is set as 0；
(4) the connected domain detection in the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block, if be not connected to
Domain, then terminate algorithm, reminds with detecting again；
(5) inner void filling is carried out to the connected domain that detection obtains；
12, the corresponding foreground area of connected domain on area-of-interest figure Bound_ROI_fine_i accurate to indicator paper block
Corroded, to eliminate noise jamming, completes indicator paper block positioning；
13, the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block of each final indicator paper block is to colour
Image Img_color is traversed, and the accurate area-of-interest figure Bound_ROI_fine_i institute of the indicator paper block of analysis test paper block is right
The rgb value for each pixel answered；Calculate the mean value of the RGB in the region.
Further, the camera in step 1 at the top of urine detection instrument is mounted on above indicator paper block center, that is, is located at
Image center；Indicator paper block right boundary is in the vertical direction of image；The resolution ratio of camera image is ten thousand picture of 30-1000
Element；
Further, step 3 indicator paper block detection binaryzation empirical value Th_strip is 50-100；
Further, step 4 carries out binaryzation to gray level image Img_gray, obtains the tool of foreground image Img_fore
Steps are as follows for body:
(1) foreground image Img_fore and the same size of gray level image Img_gray；
(2) brightness value of each of foreground image Img_fore pixel, is set as 0；
(3) each of gray level image Img_gray pixel is traversed, if the brightness value of the pixel is greater than threshold value
Th_strip, then the brightness value that the pixel of foreground image Img_fore corresponding position is arranged is 255, otherwise, is set as 0；
Further, step 5 paper slip outline border positions, and obtains indicator paper block area-of-interest figure Img_ROI, specific steps are such as
Under:
(1) connected domain analysis is carried out to foreground image Img_fore；After being detected by connected domain, it is available each
Exterior contour, the connected domain interior pixels label of connected domain；
(2) if there is no connected domain, it is basic just without indicator paper block in field of view to illustrate, urine detection instrument algorithm stops
Only, then user is reminded to check, or re-starts detection；
(3) inner void filling is carried out to the connected domain detected；
(4) area of each connected domain is calculated；By the maximum connected domain of area, as the corresponding region of indicator paper block；
(5) area value in largest connected domain is if it is less than area lowest threshold Th_area_bound, urine detection instrument algorithm
Stop, reminding user to detect again, obtain indicator paper block area-of-interest figure Img_ROI；Indicator paper block area-of-interest figure Img_ROI
With indicator paper block picture size is completely the same and grayscale image；By each pixel of indicator paper block area-of-interest figure Img_ROI
It is set as 0；Each pixel inside indicator paper block outline border will be located in indicator paper block area-of-interest figure Img_ROI, on position,
It is both configured to 255；
Further, step 6 indicator paper block black outline border detection binaryzation empirical value Th_bound is 100-200；
Further, step 10 indicator paper block interior zone detection threshold value Th_bound_inner is 20-80.
After adopting the above scheme, the indicator paper block of the accurate positioning of a kind of urine detection of the present invention has following
Advantage:
1, indicator paper block shift in position will not influence the result of algorithm；
2, available accurately indicator paper block outer boundary, pixel utilization rate is very high, and the color average of calculating is more smart
It is quasi-；
3, indicator paper block outer boundary positioning accuracy is high, will not introduce external noise pixel, reduce the accurate of color average
Property；
4, camera colour cast will not impact, and the outline border of indicator paper block is black, not influenced by colour cast；
5, the borderline possible shade of indicator paper block, will not impact；Shade is also black, can melt with outline border for
One, detected as a whole, does not influence；
6, the radial distortion in image caused by optical lens will not impact the result of detection；
7, the algorithm speed of service is fast, and calculation amount is low.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
Some embodiments of invention without any creative labor, may be used also for those of ordinary skill in the art
To obtain other drawings based on these drawings.
Fig. 1 is structural schematic diagram of the invention；
Fig. 2 is the positioning of indicator paper block outline border, obtains the specific flow chart of indicator paper block area-of-interest figure Img_ROI；
Fig. 3 is traversal foreground picture Img_fore4, carries out the flow chart of the connected domain detection of black outline border；
Fig. 4 obtains the accurate area-of-interest figure of indicator paper block on the basis of indicator paper block area-of-interest figure Bound_ROI_i
The specific flow chart of Bound_ROI_fine_i.
Description of symbols:
1, handle portion；2, rectangular panel portion；3, black outline border；4, small indicator paper block；5, it is inserted into indication wire；6, arrow prompt figure
Mark；7, patch.
Specific embodiment
With reference to the accompanying drawing, the present invention is further illustrated.
Referring to shown in Fig. 1, present embodiment the technical solution adopted is that: it includes strip of test-paper, white
Thin substrate；The strip thin substrate of white is made of the PVC plastic of thickness 0.5mm, and thickness thickeies, so that test-paper is using
Shi Buyi bending, deformation, more durable stable；Strip thin substrate includes integrally formed rectangular panel portion 2 and handle portion 1；Examination
The scraps of paper are located on rectangular panel portion 2；Test-paper is equipped with 16 4*4 and equidistantly arranges small indicator paper block 4；Between between small indicator paper block 4
Away from for 2mm；The spacing on small indicator paper block 4 and 2 boundary of rectangular panel portion is 4-6mm；Small indicator paper block 4 includes leucocyte reagent block, white
With reference to color lump one, white reference color lump two, ascorbic acid reagent block, nitrite reagent block, pH value reagent block, ketoboidies reagent
Block, urinary calcium reagent block, urobilinogen reagent block, occult blood reagent block, bilirubin reagent block, creatinine reagent block, protein reagent block, urine
Specific gravity reagent block, glucose reagent block, microalbumin reagent block summarize 14 Testing index relevant to health in urine
On a test-paper, shape is more beautiful, quality is more durable, it is convenient, fast, practical, beautiful to have the advantages that, innovation,
Not only it was convenient to use, but also improves efficiency；Rectangular panel portion 2 is located at the outside of each small indicator paper block 4 and is close to small indicator paper block
Position is equipped with black outline border 3；The line thickness of black outline border 3 is 0.5mm；Spacing between two neighboring black outline border 3 is
1mm, the position that automatic checkout equipment passes through detection black outline border 3 in the picture, so that it may obtain the essence of each small indicator paper block 4
True position；When shooting, camera is some part subject for facing indicator paper block center vertical view, therefore being not in black outline border 3
The phenomenon that paper material is blocked not will cause the phenomenon that test paper outline border is broken in foreground picture；The middle part of test-paper is along width
Direction is equipped with an insertion indication wire 5, to prompt user's test-paper to be inserted into this position；The middle and lower part of test-paper is along length
It spends direction and is equipped with arrow prompt icon 6, for prompting user when in use by icon instruction direction insertion urine detection instrument；In arrow
The lower section of head prompt icon 6 is marked equipped with " This side up ", for reminding user, prevents from the up and down direction of indicator paper block doing anti-；
The edge of test-paper is equipped with rounding off so that entire test-paper from the appearance from the point of view of more mellow and fuller beauty, keep away in use
Exempt from due to the strict situation for causing user's experience sense poor of corner point；The width of handle portion 1 is 20mm；Handle portion 1 is equipped with patch
Piece 7 facilitates user that can take when in use test paper；
Rectangular panel portion 2 is white, and the pedestal of urine detection instrument is using the color being easy to white differentiation, automatically when detection,
It is easy to positioning in the picture and obtains 2 outline border position of rectangular panel portion；And rectangular panel portion 2 is white, black with indicator paper block surrounding
3 collective effect of color frame, so that indicator paper block is more easier to position；
The localization method of indicator paper block comprises the following steps:
One, indicator paper block is impregnated in urine 1-3 seconds, indicator paper block is then inserted into urine detection instrument；At the top of urine detection instrument
Camera shoot image；Urine detection instrument guarantees that the indicator paper block of inside does not have exterior light according to interference, guarantees the light on indicator paper block
According to being sufficient, uniform；Camera at the top of urine detection instrument is mounted on above indicator paper block center, that is, is located at image and is hit exactly
The heart；Indicator paper block right boundary is in the vertical direction of image；The resolution ratio of camera image is ten thousand pixel of 30-1000；Stress speed
When spending, the resolution ratio of 300,000 pixels can be used；Stress precision, then can use the resolution ratio of 10,000,000 pixels；
Two, gray level image Img_gray is converted by color image Img_color, gray scale value calculating method has following three
Kind:
(1) gray value is obtained to tri- path computation average values of RGB；
(2) utilize weighted formula: Gray=R*0.299+G*0.587+B*0.114 calculates to obtain gray value；
(3) using the maximum value in RGB tri- values as gray value；
Three, it sets indicator paper block and detects binaryzation empirical value Th_strip as 100；Test strips detect binaryzation empirical value
Th_strip can be changed between 50-150, be carried out according to urine detection instrument interior lights photograph, pedestal brightness, bottom plate brightness
Flexibly setting；But it once sets, after software publication, which is just secured；Except non-update software, the otherwise use of urine detection instrument
In the process, test strips detection binarization threshold Th_strip will not change；
Four, binaryzation is carried out to gray level image Img_gray, foreground image Img_fore is obtained, due in indicator paper block image
The pixel in only indicator paper block region is white, and the region other than indicator paper block is entirely black, the specific steps are as follows:
(1) foreground image Img_fore and the same size of gray level image Img_gray；
(2) brightness value of each of foreground image Img_fore pixel, is set as 0；
(3) each of gray level image Img_gray pixel is traversed, if the brightness value of the pixel is greater than threshold value
Th_strip, then the brightness value that the pixel of foreground image Img_fore corresponding position is arranged is 255, otherwise, is set as 0；
Five, indicator paper block outline border positions, and obtains indicator paper block area-of-interest figure Img_ROI, referring to shown in Fig. 2, specific steps
It is as follows:
(1) connected domain analysis is carried out to foreground image Img_fore；After being detected by connected domain, it is available each
Exterior contour, the connected domain interior pixels label of connected domain；
(2) if there is no connected domain, it is basic just without indicator paper block in field of view to illustrate, urine detection instrument algorithm stops
Only, then user is reminded to check, or re-starts detection；
(3) inner void filling is carried out to the connected domain detected；
(4) area of each connected domain is calculated；By the maximum connected domain of area, as the corresponding region of indicator paper block；
(5) area value in largest connected domain is if it is less than area lowest threshold Th_area_bound, area lowest threshold
Th_area_bound is set as 10000, and urine detection instrument algorithm stops, and reminds user to detect again, it is interested to obtain indicator paper block
Administrative division map Img_ROI；Indicator paper block area-of-interest figure Img_ROI and indicator paper block picture size is completely the same and grayscale image；It will
Each pixel of indicator paper block area-of-interest figure Img_ROI is set as 0；By in indicator paper block area-of-interest figure Img_ROI,
Each pixel being located inside indicator paper block outline border on position, is both configured to 255；
Six, it sets indicator paper block black outline border and detects binaryzation empirical value Th_bound as 150；The inspection of indicator paper block black outline border
Surveying binaryzation empirical value Th_bound can be changed between 100-200, be shone according to detector interior lights, black outline border
Brightness, bottom plate brightness etc. are flexibly set；But it once sets, after software publication, which is just secured；Except non-update software,
Otherwise in the use process of detector, which will not change；
Seven, in conjunction with gray level image Img_gray and indicator paper block area-of-interest figure Img_ROI, binaryzation is carried out, before obtaining
Scape image Img_fore2, the specific method is as follows:
(1) foreground image Img_fore2 is identical as gray level image Img_gray size；
(2) 0 is set by each pixel brightness value of foreground image Img_fore2；
(3) each of gray level image Img_gray pixel is traversed, if the corresponding indicator paper block sense of the location of pixels
The brightness value of interest administrative division map Img_ROI is 0, then does not handle；Otherwise, if the pixel brightness value in gray level image Img_gray
Lower than threshold value Th_bound, then 255 are set by the respective pixel value brightness in foreground image Img_fore2, if being higher than threshold
Value Th_bound, then be set as 0；
Eight, in conjunction with color image Img_color and indicator paper block area-of-interest figure Img_ROI, detection obtains foreground image
Img_fore3, the specific method is as follows:
(1) foreground image Img_fore3 is identical as gray level image Img_gray size；
(2) 0 is set by each pixel brightness value of foreground image Img_fore3；
(3) each of color image Img_color pixel is traversed；If the corresponding Img_ROI of the location of pixels
The brightness value of figure is 0, then does not handle；Otherwise, if as long as RGB tri- of position pixel values in color image Img_color
There is one to be less than threshold value Th_bound, then sets 255 for the respective pixel value brightness in foreground image Img_fore3, unless
RGB tri- values are both greater than Th_bound, are just set as 0；
(4) by image or operation, carry out Img_fore2 and Img_fore3 to be fused to Img_fore4；
Nine, foreground picture Img_fore4 is traversed, the connected domain detection of black outline border, shown referring to Fig. 3, specific method are carried out
It is as follows:
(1) connected domain detects, if connected domain number is less than 16, algorithm is terminated in advance, early warning, prompts user again
Detection；
(2) connected domain inner void is filled；
(3) area of all connected domains is calculated；
(4) maximum 16 connected domains of area are extracted；If the area of this 16 connected domains is both greater than empirical value Th_
Area_patch then carries out subsequent step；Otherwise, algorithm terminates in advance, early warning, and user is prompted to detect again；
(5) this 16 connected domains are directed to, the indicator paper block area-of-interest figure Img_ for obtaining each connected domain is calculated separately
ROI, the specific method is as follows:
A, it is directed to i-th of connected domain, establishes indicator paper block area-of-interest figure Bound_ROI_i, the figure size and grayscale image
Picture Img_gray is consistent, and each pixel value of indicator paper block area-of-interest figure Bound_ROI_i is set as 0；
B, for each pixel inside i-th of connected domain, in corresponding position by indicator paper block area-of-interest figure
Pixel value in Bound_ROI_i is set as 255；
Ten, indicator paper block interior zone detection threshold value Th_bound_inner is set as 50；Indicator paper block interior zone detection threshold
Value Th_bound_inner can be changed between 20-80, be shone according to detector interior lights, the brightness of black outline border, bottom plate
Brightness etc. is flexibly set；But it once sets, after software publication, which is just secured；Except non-update software, otherwise detector
Use process in, which will not change；
11, on the basis of indicator paper block area-of-interest figure Bound_ROI_i, the accurate area-of-interest of indicator paper block is obtained
Scheme Bound_ROI_fine_i, referring to shown in Fig. 4, the specific method is as follows:
(1) the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block and the same size of gray level image Img_gray, often
One pixel brightness value is set as 0；
(2) traversing each of indicator paper block area-of-interest figure Bound_ROI_i image white pixel, i.e. brightness value is
255 pixel；
(3) if respective pixel in gray level image Img_gray, brightness value is higher than indicator paper block interior zone detection threshold
Value Th_bound_inner, then by the respective pixel brightness value in the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block
It is set as 255；Otherwise, if RGB tri- of position pixel values in color image Img_color, as long as there is one to be higher than examination
Paper block interior zone detection threshold value Th_bound_inner, also by the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block
In respective pixel brightness value be set as 255；It otherwise, will be in the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block
Respective pixel brightness value is set as 0；
(4) the connected domain detection in the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block, if be not connected to
Domain, then terminate algorithm, reminds with detecting again；
(5) inner void filling is carried out to the connected domain that detection obtains；
12, the corresponding foreground area of connected domain on area-of-interest figure Bound_ROI_fine_i accurate to indicator paper block
Corroded, to eliminate noise jamming, completes indicator paper block positioning；
13, the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block of each final indicator paper block is to colour
Image Img_color is traversed, and the accurate area-of-interest figure Bound_ROI_fine_i institute of the indicator paper block of analysis test paper block is right
The rgb value for each pixel answered；Calculate the mean value of the RGB in the region.
The above is merely illustrative of the technical solution of the present invention, rather than limits those of ordinary skill in the art to this hair
The other modifications or equivalent replacement that bright technical solution is made, as long as it does not depart from the spirit and scope of the technical scheme of the present invention,
It is intended to be within the scope of the claims of the invention.
Claims (10)
1. a kind of indicator paper block of the accurate positioning of urine detection, it is characterised in that its strip comprising test-paper, white is thin
Substrate；The strip thin substrate of white includes integrally formed rectangular panel portion and handle portion；Test-paper is located on rectangular panel portion；Examination
The scraps of paper equidistantly arrange small indicator paper block equipped with several；Rectangular panel portion is located at the outside of each small indicator paper block and is close to small test paper
The position of block is equipped with black outline border；The middle part of test-paper is equipped with an insertion indication wire in the width direction；Under in test-paper
Portion is equipped with arrow prompt icon along its length, marks in the lower section of arrow prompt icon equipped with " This side up "；Test-paper
Edge is equipped with rounding off.
2. a kind of indicator paper block of the accurate positioning of urine detection according to claim 1, it is characterised in that the examination
The scraps of paper are equipped with leucocyte reagent block, white reference color lump one, white reference color lump two, ascorbic acid reagent block, nitrite
Reagent block, pH value reagent block, ketoboidies reagent block, urinary calcium reagent block, urobilinogen reagent block, occult blood reagent block, bilirubin reagent
Block, creatinine reagent block, protein reagent block, specific gravity of urine reagent block, glucose reagent block, microalbumin reagent block.
3. a kind of indicator paper block of the accurate positioning of urine detection according to claim 1, it is characterised in that small indicator paper block
Between spacing be 2mm；The spacing on small indicator paper block and boundary is 4-6mm；Strip thin substrate with a thickness of 0.5mm；Strip
The line thickness of black outline border is 0.5mm in thin substrate；Spacing between two neighboring black outline border is 1mm；The width of handle portion
Degree is 20mm；Handle portion is equipped with patch.
4. a kind of indicator paper block of the accurate positioning of urine detection according to claim 1, it is characterised in that indicator paper block
Localization method comprises the following steps:
One, indicator paper block is impregnated in urine 1-3 seconds, indicator paper block is then inserted into urine detection instrument；Taking the photograph at the top of urine detection instrument
As head shoots image；
Two, gray level image Img_gray is converted by color image Img_color, gray scale value calculating method there are following three kinds:
(1) gray value is obtained to tri- path computation average values of RGB；
(2) utilize weighted formula: Gray=R*0.299+G*0.587+B*0.114 calculates to obtain gray value；
(3) using the maximum value in RGB tri- values as gray value；
Three, setting indicator paper block detects binaryzation empirical value Th_strip；
Four, binaryzation is carried out to gray level image Img_gray, obtains foreground image Img_fore；
Five, indicator paper block outline border positions, and obtains indicator paper block area-of-interest figure Img_ROI；
Six, setting indicator paper block black outline border detects binaryzation empirical value Th_bound；
Seven, in conjunction with gray level image Img_gray and indicator paper block area-of-interest figure Img_ROI, binaryzation is carried out, foreground picture is obtained
As Img_fore2, the specific method is as follows:
(1) foreground image Img_fore2 is identical as gray level image Img_gray size；
(2) 0 is set by each pixel brightness value of foreground image Img_fore2；
(3) each of gray level image Img_gray pixel is traversed, if the corresponding indicator paper block of the location of pixels is interested
The brightness value of administrative division map Img_ROI is 0, then does not handle；Otherwise, if the pixel brightness value is lower than in gray level image Img_gray
Threshold value Th_bound then sets 255 for the respective pixel value brightness in foreground image Img_fore2, if being higher than threshold value Th_
Bound is then set as 0；
Eight, in conjunction with color image Img_color and indicator paper block area-of-interest figure Img_ROI, detection obtains foreground image Img_
Fore3, the specific method is as follows:
(1) foreground image Img_fore3 is identical as gray level image Img_gray size；
(2) 0 is set by each pixel brightness value of foreground image Img_fore3；
(3) each of color image Img_color pixel is traversed；If the corresponding Img_ROI figure of the location of pixels
Brightness value is 0, then does not handle；Otherwise, if as long as tri- values of RGB of the position pixel have one in color image Img_color
It is a to be less than threshold value Th_bound, then 255 are set by the respective pixel value brightness in foreground image Img_fore3, unless RGB tri-
A value is both greater than Th_bound, is just set as 0；
(4) by image or operation, carry out Img_fore2 and Img_fore3 to be fused to Img_fore4；
Nine, foreground picture Img_fore4 is traversed, carries out the connected domain detection of black outline border, the specific method is as follows:
(1) connected domain detects, if connected domain number is less than the quantity of small indicator paper block, algorithm is terminated in advance, early warning, prompts to use
Again it detects at family；
(2) connected domain inner void is filled；
(3) area of all connected domains is calculated；
(4) connected domain that area maximum quantity is equal to the quantity of small indicator paper block is extracted；If the area of these connected domains is both greater than
Empirical value Th_area_patch then carries out subsequent step；Otherwise, algorithm terminates in advance, early warning, and user is prompted to detect again；
(5) these connected domains are directed to, calculate separately the indicator paper block area-of-interest figure Img_ROI for obtaining each connected domain, specifically
Method is as follows:
A, it is directed to i-th of connected domain, establishes indicator paper block area-of-interest figure Bound_ROI_i, the figure size and gray level image
Img_gray is consistent, and each pixel value of indicator paper block area-of-interest figure Bound_ROI_i is set as 0；
B, for each pixel inside i-th of connected domain, in corresponding position by indicator paper block area-of-interest figure Bound_
Pixel value in ROI_i is set as 255；
Ten, indicator paper block interior zone detection threshold value Th_bound_inner is set；
11, on the basis of indicator paper block area-of-interest figure Bound_ROI_i, the accurate area-of-interest figure of indicator paper block is obtained
Bound_ROI_fine_i, the specific method is as follows:
(1) the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block and the same size of gray level image Img_gray, each
Pixel brightness value is set as 0；
(2) each of indicator paper block area-of-interest figure Bound_ROI_i image white pixel is traversed, i.e. brightness value is 255
Pixel；
(3) if respective pixel in gray level image Img_gray, brightness value is higher than indicator paper block interior zone detection threshold value Th_
Then the respective pixel brightness value in the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block is arranged by bound_inner
It is 255；Otherwise, if RGB tri- of position pixel values in color image Img_color, as long as there is one to be higher than indicator paper block
Interior zone detection threshold value Th_bound_inner, also will be in the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block
Respective pixel brightness value is set as 255；Otherwise, by the correspondence in the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block
Pixel brightness value is set as 0；
(4) the connected domain detection in the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block, if without connected domain,
Terminate algorithm, reminds with detecting again；
(5) inner void filling is carried out to the connected domain that detection obtains；
12, the corresponding foreground area of connected domain on area-of-interest figure Bound_ROI_fine_i accurate to indicator paper block carries out
Corrosion completes indicator paper block positioning to eliminate noise jamming；
13, the accurate area-of-interest figure Bound_ROI_fine_i of indicator paper block of each final indicator paper block is to color image
Img_color is traversed, corresponding to the accurate area-of-interest figure Bound_ROI_fine_i of the indicator paper block of analysis test paper block
The rgb value of each pixel；Calculate the mean value of the RGB in the region.
5. a kind of indicator paper block of the accurate positioning of urine detection according to claim 4, it is characterised in that in step 1
Camera at the top of urine detection instrument is mounted on above indicator paper block center, that is, is located at image center；Indicator paper block right boundary
Vertical direction in image；The resolution ratio of camera image is ten thousand pixel of 30-1000.
6. a kind of indicator paper block of the accurate positioning of urine detection according to claim 4, it is characterised in that step 3 examination
It is 50-100 that paper block, which detects binaryzation empirical value Th_strip,.
7. a kind of indicator paper block of the accurate positioning of urine detection according to claim 4, it is characterised in that step 4 pair
Gray level image Img_gray carries out binaryzation, and obtaining foreground image Img_fore, specific step is as follows:
(1) foreground image Img_fore and the same size of gray level image Img_gray；
(2) brightness value of each of foreground image Img_fore pixel, is set as 0；
(3) each of gray level image Img_gray pixel is traversed, if the brightness value of the pixel is greater than threshold value Th_
Strip, then the brightness value that the pixel of foreground image Img_fore corresponding position is arranged is 255, otherwise, is set as 0.
8. a kind of indicator paper block of the accurate positioning of urine detection according to claim 4, it is characterised in that step 5 paper
The positioning of outline border, obtains indicator paper block area-of-interest figure Img_ROI, the specific steps are as follows:
(1) connected domain analysis is carried out to foreground image Img_fore；After being detected by connected domain, each available connection
Exterior contour, the connected domain interior pixels label in domain；
(2) if there is no connected domain, it is basic just without indicator paper block in field of view to illustrate, urine detection instrument algorithm stops, so
It reminds user to check afterwards, or re-starts detection；
(3) inner void filling is carried out to the connected domain detected；
(4) area of each connected domain is calculated；By the maximum connected domain of area, as the corresponding region of indicator paper block；
(5) area value in largest connected domain stops if it is less than area lowest threshold Th_area_bound, urine detection instrument algorithm
Only, it reminds user to detect again, obtains indicator paper block area-of-interest figure Img_ROI；Indicator paper block area-of-interest figure Img_ROI with
Indicator paper block picture size is completely the same and grayscale image；Each pixel of indicator paper block area-of-interest figure Img_ROI is set
It is set to 0；Each pixel inside indicator paper block outline border will be located in indicator paper block area-of-interest figure Img_ROI, on position, all
It is set as 255.
9. a kind of indicator paper block of the accurate positioning of urine detection according to claim 4, it is characterised in that step 6 examination
It is 100-200 that paper block black outline border, which detects binaryzation empirical value Th_bound,.
10. a kind of indicator paper block of the accurate positioning of urine detection according to claim 4, it is characterised in that step 10 examination
Paper block interior zone detection threshold value Th_bound_inner is 20-80.
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Cited By (1)
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