CN107315003A - A kind of urine test paper reacts colour analysis method - Google Patents

A kind of urine test paper reacts colour analysis method Download PDF

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Publication number
CN107315003A
CN107315003A CN201710505384.6A CN201710505384A CN107315003A CN 107315003 A CN107315003 A CN 107315003A CN 201710505384 A CN201710505384 A CN 201710505384A CN 107315003 A CN107315003 A CN 107315003A
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color
test paper
urine test
photoenvironment
feature
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佩京帕特里克
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Shenzhen Palm Medical Technology Co Ltd
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Shenzhen Palm Medical Technology Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/90Determination of colour characteristics

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  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Theoretical Computer Science (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention discloses a kind of urine test paper reaction colour analysis method.The present invention puts the Urine test paper image in area by gathering comprising Urine test paper to be checked, the photoenvironment feature in detection process and the color characteristic of camera device are marked using Urine test paper blank, photoenvironment feature and camera device color characteristic in detection process are marked using the test paper rest area background of given color simultaneously, the color data of the urine to be measured examination under different photoenvironments and different mobile phone camera color characteristics is obtained.The interference of difference of different photoenvironments and camera device can be excluded by implementing the present invention, and accurate, reliable urine examination result is obtained in the way of low cost.

Description

A kind of urine test paper reacts colour analysis method
Technical field
Colour analysis method is reacted the present invention relates to a kind of urine test paper.
Background technology
Current urine biochemistry analysis is used as answering in terms of medical diagnosis on disease, prevention from suffering from the diseases and health status generaI investigation in medical domain With more and more extensive.Urine biochemistry analysis method mainly has liquid chromatography, arena force microscopy and dry chemical method.Liquid Phase chromatography equipment is expensive, operation is complicated with data analysis, is generally used for urine metabolism group credit analysis;Arena microscopic analysis Sample preparation flow is cumbersome, efficiency is low, mainly carries out special analysis to detections such as leucocyte, red blood cell and Urine proteins crystallizations;Desiccation Method is to be reacted using routine inspection in the dry chemistry reagent and urine being adsorbed on test paper and occurred color change, and The concentration of corresponding chemical composition in urine is determined according to color change degree.Dry chemical method urine detection speed is fast, project is more, Reproducible, accuracy is higher, it is adaptable to high-volume Urine specimens screening.
Dry chemical method urinalysis technology is quantitatively examined according to the reflectivity of specific wavelength after urine and test paper reaction Survey, it is necessary to light intensity and the constant monochromatic source of optical wavelength, but the light source luminescent intensity of current dry chemical uroscopy instrument will be with Decayed using duration, and wavelength will also drift about, it is therefore desirable to and periodically calibration calibrates to reduce error, in addition, urine examination Instrument needs to shield the interference of ambient light, and volume is big, outdoor inconvenient for use.
With the popularization of smart mobile phone, it is each that those skilled in the art start with smart mobile phone camera shooting Urine test paper Detection reacts color image, determines to react color change degree by image recognition and color analysis, and then obtain urine and respectively examine Survey item concentration.The characteristics of this uroscopy mode has convenient, cheap, rapid.But due to the smart mobile phone of different brands, or The same brand different batches of person, the sensor of the smart mobile phone of different model, lens parameters and image processing algorithm are different, Its color output characteristics difference is big, that is, shoots and take same Urine test paper to obtain color data difference, at present more using calibration Mode obtains rgb space to the conversion coefficient of cie color system, but smart mobile phone model substantial amounts, sensor, camera lens ginseng Number and image processing algorithm vary, and cause calibration work very numerous and diverse, it is difficult to cover most users demand.
In addition, user using smart mobile phone when shooting Urine test paper image progress color analysis, even if the intelligence after calibration Energy mobile phone, there is also under big difference, particularly daylight and light background for the color data obtained in different photoenvironments There were significant differences for test paper color.The color distortion of shooting image will cause urine color analysis unstable result, and influence checks knot The accuracy and reliability of fruit.
The content of the invention
It is an object of the present invention to provide the urine test paper reaction colour analysis of a kind of low cost, high accuracy, high reliability Method, when considering collection image while the image of urine test paper is gathered using camera device and recognizes that urine reacts color The influence of photoenvironment and camera device optical parametric to measurement result, so as to obtain accurate measurement result.
Colour analysis method is reacted the invention provides a kind of urine test paper, is comprised the following steps:Obtained using camera device Image on Urine test paper to be checked;Photoenvironment feature during recognition detection;Obtain the color of the camera device for detection Feature;Extract the color characteristic that each detection project block of Urine test paper to be checked reacts color;According to the photoenvironment feature and taking the photograph As the color characteristic of device matches the color characteristic of known photoenvironment feature and camera device in database, matching is obtained The color characteristic of photoenvironment feature and camera device;Existed according to the color characteristic of the photoenvironment feature of matching and camera device Matching and the immediate known Urine test paper of color characteristic of Urine test paper to be checked each detection project block reaction color in database Detection project block reacts the color characteristic of color, wherein, different known photoenvironment features and difference are included in the database The color characteristic of each detection project block reaction color known to Urine test paper under known camera color feature and its corresponding Detection project concentration data;Immediate known Urine test paper detection project block is reacted to the corresponding detection of color characteristic of color Concentration data as corresponding detection testing result.
Further, the step of photoenvironment feature during the recognition detection includes:Extract urine to be checked in described image Color component Xi, Yi, Zi of liquid test paper white space;Extract the color for the background area for not including Urine test paper region in image Component Xj, Yj, Zj;Photoenvironment signature is vector Mi (Xi, Yi, Zi, Xj, Yj, Zj).
Further, it is described obtain for the camera device of detection color characteristic the step of include:Extract and treated in image Examine color component xi, yi, zi of Urine test paper white space;Extract and Urine test paper field color component is free of in image background xj、yj、zj;Camera device color characteristic is labeled as vector mi=(xi, yi, zi, xj, yj, zj).
Further, the light according to known to the color characteristic of the photoenvironment feature and camera device is matched in database According to environmental characteristic and camera device color characteristic the step of include:Calculate in the photoenvironment feature and the database First angle theta 1 of each known photoenvironment feature;Calculate the camera device color characteristic vector with it is each in the database Second angle theta 2 of known camera device color characteristic;Choose the known illumination ring for making the product of the first angle and the second angle minimum Border feature and camera device color characteristic as matching photoenvironment feature and camera device color characteristic.
Further, the known photoenvironment feature of difference that methods described is also included in acquisition database is taken the photograph with Bu Tong known As the color characteristic and its corresponding detection concentration of each detection project block reaction color of the Urine test paper under head color characteristic The step of data.
Further, the known photoenvironment feature of difference and Bu Tong known camera color in the acquisition database are special The step of each detection project block of Urine test paper under levying reacts the color characteristic and its corresponding detection concentration data of color Comprise the following steps:Obtained under different photoenvironments by different cameras comprising reacted with the urine of each given concentration The a series of images of Urine test paper;Photoenvironment feature is marked using the color characteristic of the Urine test paper white space in the image With camera device color characteristic;Photoenvironment feature and camera device are marked using the background of the test paper rest area of given color Color characteristic;Color characteristic of the Urine test paper under given each given concentration is detected, so as to obtain different photoenvironments and not With color characteristic of the Urine test paper under camera device color characteristic under given each detection concentration.
The beneficial effects of the invention are as follows:
1) present invention utilizes 6 dimensions by gathering reaction color image of the concentration known Urine test paper in different photoenvironments Degree vector color labeling method to carry out quantitative analysis and sophisticated category to photoenvironment, is carrying out Urine test paper reaction color to be checked During colour recognition, it can determine and its quantitative photoenvironment, testing result is not influenceed by photoenvironment.
2) present invention utilizes vector face by gathering reaction color image of the concentration known Urine test paper to different camera devices Color marker method to carry out quantitative analysis and sophisticated category to camera color feature, is carrying out Urine test paper reaction color face to be checked When color is recognized, its camera device color characteristic is can determine, is eliminated because of different model or the color distortion of the camera device of batch Influence.
3) present invention by the way of Urine test paper blank and given background color are combined come quantitative analysis photoenvironment Feature and camera device color characteristic so that photoenvironment feature and the special feature of camera device color have more dimensional informations, The accuracy of identification is improved, and can eliminate that uneven illumination is even, shade influence by selecting multiple spot background area.
Brief description of the drawings
Fig. 1 is the flow chart that colour analysis method is reacted according to the urine test paper of an embodiment of the invention;
Fig. 2 is the image according to an embodiment of the invention on Urine test paper to be checked
Fig. 3 is that the color characteristic according to the photoenvironment feature and camera device in Fig. 1 is matched in database The detail flowchart for the step of knowing the color characteristic of photoenvironment feature and camera device;
Fig. 4 is photoenvironment feature and not known to difference in the acquisition database of an embodiment of the invention With the color characteristic of each detection project block reaction color known to the Urine test paper under known camera color feature and its correspondingly Detection concentration data flow chart.
Embodiment
Below in conjunction with accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete Ground is described, it is clear that described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Generally exist The component of the embodiment of the present invention described and illustrated in accompanying drawing can be arranged and designed with a variety of configurations herein.Cause This, the detailed description of the embodiments of the invention to providing in the accompanying drawings is not intended to limit claimed invention below Scope, but it is merely representative of the selected embodiment of the present invention.Based on embodiments of the invention, those skilled in the art are not doing The every other embodiment obtained on the premise of going out creative work, belongs to the scope of protection of the invention.
Fig. 1 is the flow chart that colour analysis method is reacted according to the urine test paper of an embodiment of the invention.Such as Fig. 1 institutes Show, urine test paper reaction colour analysis method comprises the following steps:
Step S101, the image on Urine test paper to be checked is obtained using camera device;Camera device can be camera, Digital camera etc..Fig. 2 is the image according to an embodiment of the invention on Urine test paper to be checked.As shown in Fig. 2 image In Urine test paper be positioned over test paper rest area, test paper rest area is provided with the background area with particular color.Urine test paper has There are some detection project blocks, and the white space beyond detection project block.It is specific provided with detecting in detection project block The reagent of urine detection project.Same detection project may have a variety of different reagents.These reagents are in the urine with heterogeneity Corresponding color can be showed after reaction.
Step S102, photoenvironment feature during recognition detection;Further, photoenvironment feature during recognition detection Step can include:(this sentences RGB color to color component Xi, Yi, Zi of Urine test paper white space to be checked in extraction described image Exemplified by color pattern, i.e. R=Xi, G=Yi, B=Zi);Extract the color for the background area for not including Urine test paper region in image Component Xj, Yj, Zj;Photoenvironment signature is vector (Xi, Yi, Zi, Xj, Yj, Zj).Extract Urine test paper clear area to be checked During the color component in domain, one or more pixel in the white space in image can be selected, according to selected pixel The color component of point determines the color component of white space.
Step S103, obtains the color characteristic of the camera device for detection;Further, the shooting for detection is obtained The step of color characteristic of device, can include:Extract the color component xi of Urine test paper white space to be checked in image, yi, zi;Extract and Urine test paper field color component xj, yj, zj are free of in image background;Camera device color characteristic is labeled as vector (xi, yi, zi, xj, yj, zj).
Step S104, extracts the color characteristic that each detection project block of Urine test paper to be checked reacts color;Specifically, can be with The color value that each detection project block of test paper to be checked reacts color is extracted by image processing algorithm.
Step S105, obtains the photoenvironment feature of matching and the color characteristic of camera device;Specifically, according to described The color characteristic of photoenvironment feature and camera device matches known photoenvironment feature and the face of camera device in database Color characteristic, to obtain the photoenvironment feature of matching and the color characteristic of camera device, wherein, difference is included in the database Known photoenvironment feature and each detection project block reaction known to the Urine test paper under Bu Tong known camera color feature The color characteristic of color and its corresponding detection project concentration data.In combination with Fig. 3, according to the photoenvironment feature and shooting The step of color characteristic of device matches the color characteristic of known photoenvironment feature and camera device in database includes:Step Rapid S1051, calculates the first angle theta 1 of the photoenvironment feature and each known photoenvironment feature in the database;Step Rapid S1052, calculates the camera device color characteristic vector and is sweared with each known camera device color characteristic in the database Second angle theta 2 of amount;Step S1053, chooses the known photoenvironment Characteristic Vectors for making the product of the first angle and the second angle minimum Measure photoenvironment feature and camera device color characteristic as matching with camera device color characteristic vector.
Step S106, obtains the color characteristic that immediate known Urine test paper detection project block reacts color;It is specific next Say, matched and respectively examined with Urine test paper to be checked in database according to the color characteristic of the photoenvironment feature of matching and camera device The immediate known Urine test paper detection project block of color characteristic for surveying Project Areas deblocking reaction color reacts the color characteristic of color.
Step S107, obtains the testing result of corresponding detection, specifically, and immediate known Urine test paper is detected The corresponding detection concentration data of color characteristic of Project Areas deblocking reaction color as corresponding detection testing result.
Fig. 4 is photoenvironment feature and not known to difference in the acquisition database of an embodiment of the invention With the color characteristic of each detection project block reaction color known to the Urine test paper under known camera color feature and its correspondingly Detection concentration data flow chart.As shown in figure 4, known photoenvironment features of difference in acquisition database with Bu Tong Know the color characteristic of each detection project block reaction color and its corresponding inspection known to the Urine test paper under camera color feature The step of surveying item concentration data includes:
Step S201, obtains the urine reaction included with each given concentration under different photoenvironments by different cameras The a series of images of Urine test paper afterwards;It should be noted that because same detection project may have a variety of different reagents, and this The reaction color of a little difference reagents is different.Therefore the test paper of different reagent protocols for compliant applications, can be according to reagent It is different further under different photoenvironments by different cameras gather comprising with after the reaction of the urine of each given concentration The Urine test paper with different reagents image.
Step S202, utilizes the color characteristic formal notation photoenvironment feature of the Urine test paper white space in the image With camera device color characteristic (being similar to the vector in step S102);
Step S203, photoenvironment feature and camera device face are marked using the background of the test paper rest area of given color Color characteristic (is similar to the vector in step S102);
Step S204, color characteristic of the detection Urine test paper under given each given concentration, so as to obtain different illumination Color characteristic of the Urine test paper under given each detection concentration under environment and different camera device color characteristics.
In summary, on the one hand, the present invention is by gathering reaction of the concentration known Urine test paper in different photoenvironments Color image, quantitative analysis and sophisticated category are carried out using 6 dimension vector color labeling methods to photoenvironment, to be checked in progress When Urine test paper reacts color colour recognition, it can determine and its quantitative photoenvironment, make shadow of the testing result not by photoenvironment Ring.
On the other hand, the present invention is by gathering reaction color image of the concentration known Urine test paper to different camera devices, profit Quantitative analysis and sophisticated category are carried out to camera color feature with vector color labeling method, Urine test paper to be checked is being carried out When reacting color colour recognition, its camera device color characteristic is can determine, elimination is because of the camera device of different model or batch The influence of color distortion.
Another aspect, the present invention is by the way of Urine test paper blank and given background color are combined come quantitative analysis light According to environmental characteristic and camera device color characteristic so that photoenvironment feature and the special feature of camera device color have more various dimensions Information, improves the accuracy of identification, and can eliminate that uneven illumination is even, shade influence by selecting multiple spot background area.
Any process described otherwise above or method description are construed as in flow chart or herein, represent to include Module, fragment or the portion of the code of one or more executable instructions for the step of realizing specific logical function or process Point, and the scope of the preferred embodiment of the present invention includes other realization, wherein can not be by shown or discussion suitable Sequence, including according to involved function by it is basic simultaneously in the way of or in the opposite order, carry out perform function, this should be of the invention Embodiment person of ordinary skill in the field understood.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that:Not In the case of departing from the principle and objective of the present invention a variety of change, modification, replacement and modification can be carried out to these embodiments, this The scope of invention is limited by claim and its equivalent.

Claims (6)

1. a kind of urine test paper reacts colour analysis method, it is characterised in that methods described comprises the following steps:
The image on Urine test paper to be checked is obtained using camera device;
Photoenvironment feature during recognition detection;
Obtain the color characteristic of the camera device for detection;
Extract the color characteristic that each detection project block of Urine test paper to be checked reacts color;
According to known to the color characteristic of the photoenvironment feature and camera device is matched in database photoenvironment feature and The color characteristic of camera device, obtains the photoenvironment feature of matching and the color characteristic of camera device, wherein, the database In comprising different known photoenvironment features and Bu Tong known to each detection project of known Urine test paper under camera color feature Block reacts the color characteristic and its corresponding detection project concentration data of color;
Matched according to the color characteristic of the photoenvironment feature of matching and camera device in database each with Urine test paper to be checked The immediate known Urine test paper detection project block of color characteristic of detection project block reaction color reacts the color characteristic of color;
The corresponding detection concentration data of color characteristic of immediate known Urine test paper detection project block reaction color is made For the testing result of corresponding detection.
2. urine test paper according to claim 1 reacts colour analysis method, it is characterised in that the light during recognition detection The step of according to environmental characteristic, includes:Extract color component Xi, Yi, Zi of Urine test paper white space to be checked in described image;Carry Take color component Xj, Yj, Zj of the background area not comprising Urine test paper region in image;Photoenvironment signature is vector Mi (Xi, Yi, Zi, Xj, Yj, Zj).
3. urine test paper according to claim 2 reacts colour analysis method, it is characterised in that the acquisition is used for what is detected The step of color characteristic of camera device, includes:Extract the color component xi of Urine test paper white space to be checked in image, yi, zi;Extract and Urine test paper field color component xj, yj, zj are free of in image background;Camera device color characteristic is labeled as vector Mi=(xi, yi, zi, xj, yj, zj).
4. urine test paper according to claim 3 reacts colour analysis method, it is characterised in that special according to the photoenvironment Seek peace camera device color characteristic matched in database known photoenvironment feature and camera device color characteristic step Suddenly include:
Calculate the first angle of the photoenvironment feature and each known photoenvironment feature in the database;
Calculate the second of the camera device color characteristic vector and each known camera device color characteristic in the database Angle;
Choose the known photoenvironment feature for making the product of the first angle and the second angle minimum and camera device color characteristic conduct The photoenvironment feature and camera device color characteristic of matching.
5. urine test paper according to claim 1 reacts colour analysis method, it is characterised in that methods described also includes collection The known photoenvironment feature of difference and each detection of the Urine test paper under Bu Tong known camera color feature in database The step of block reacts the color characteristic and its corresponding detection concentration data of color.
6. urine test paper according to claim 5 reacts colour analysis method, it is characterised in that in the acquisition database Different known photoenvironment features and each detection block of the Urine test paper under Bu Tong known camera color feature react color Color characteristic and its corresponding detection concentration data the step of comprise the following steps:
Obtained under different photoenvironments by different cameras comprising the reacted Urine test paper of urine with each given concentration A series of images;
Mark photoenvironment feature and camera device color special using the color characteristic of the Urine test paper white space in the image Levy;
Photoenvironment feature and camera device color characteristic are marked using the background of the test paper rest area of given color;
Color characteristic of the Urine test paper under given each detection concentration is detected, so as to obtain different photoenvironments and difference is taken the photograph As color characteristic of the Urine test paper under given each detection concentration under device color characteristic.
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CN108593645A (en) * 2018-04-24 2018-09-28 沈阳普泽众康医药科技有限公司 A kind of testing result of Urine test paper determines method and determining device
CN109856133A (en) * 2019-01-29 2019-06-07 深圳市象形字科技股份有限公司 A kind of test paper detecting method illuminated using a variety of intensities of illumination, multicolour
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CN108562548A (en) * 2018-01-26 2018-09-21 北京秒康智能科技有限公司 The color identification method and its system of intelligent urine examination closestool
CN108593645A (en) * 2018-04-24 2018-09-28 沈阳普泽众康医药科技有限公司 A kind of testing result of Urine test paper determines method and determining device
CN109856133A (en) * 2019-01-29 2019-06-07 深圳市象形字科技股份有限公司 A kind of test paper detecting method illuminated using a variety of intensities of illumination, multicolour
CN109856133B (en) * 2019-01-29 2021-06-22 深圳市象形字科技股份有限公司 Test paper detection method utilizing multiple illumination intensities and multiple color illumination
CN109900688A (en) * 2019-03-08 2019-06-18 深圳市象形字科技股份有限公司 A kind of indicator paper block of the accurate positioning of urine detection
CN110196250A (en) * 2019-05-29 2019-09-03 江汉大学 The detection method and processing equipment of Cr VI based on color component value
CN111426682A (en) * 2020-03-18 2020-07-17 重庆诺思达医疗器械有限公司 Method, device and equipment for detecting diseases and readable storage medium
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Application publication date: 20171103