CN109893462A - A kind of mild oil-control is dispelled the spraying and preparation method thereof of blackhead - Google Patents
A kind of mild oil-control is dispelled the spraying and preparation method thereof of blackhead Download PDFInfo
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- CN109893462A CN109893462A CN201910188818.3A CN201910188818A CN109893462A CN 109893462 A CN109893462 A CN 109893462A CN 201910188818 A CN201910188818 A CN 201910188818A CN 109893462 A CN109893462 A CN 109893462A
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Abstract
It dispels being sprayed of blackhead, contains the following parts by weight: 0.5-1 parts of arginine, 0.1-0.2 parts of phytic acid, 0.1-0.8 parts of silver oxide, EDTA-Na the present invention provides a kind of mild oil-control20.01-0.08 parts.Of the invention can will block the blackhead dissolution exudation of pore by spraying, while can control the secretion of grease;And it is easy to operate, do not stimulate mildly;Long-time service has effects that antibacterial anti-inflammatory, so as to repair impaired skin, improves the colour of skin, has the function that oil-water balance.
Description
Technical field
It dispels the spraying and preparation method thereof of blackhead the present invention relates to cosmetic field more particularly to a kind of mild oil-control.
Background technique
With the quickening of modern life rhythm, the increase of social pressures, the decline of air quality, and excessively use contain
There are the color make-up, bottom adornment, skin care item etc. of improper chemical component, the incidence of blackhead rises year by year, and seriously affects numerous people seeking beauties
Overall appearance.Wherein blackhead is mainly by sebum, a kind of mixture that bacterium is considered to be worth doing and the grease of secretion forms, in conjunction in air
Dust, bacterium and dirt deepen one of its ingress of air gradually since oxidation has occurred, and then blackening and block up
Plug just forms so-called blackhead at hair follicle opening over time.In general, blackhead is formed in the forehead, nose and the wing of nose of face
Around, while these positions are frequently accompanied by oil secretion, give people's greasy feeling, inevitably ask to more serious skin
Topic conversion.
There are mainly two ways for the blackhead of dispelling of current main-stream: first is that will exactly be exposed to skin using abrasive particle friction
The blackhead on surface is slowly ground off.Shortcoming is to be unable to reach the purpose of dredging pore, it is also possible to fragile epidermis is abraded, so
Say that effect is poor;Second is that abduction, is first to be expanded skin pore with steam, then blackhead is sticked with suction film and is torn it down, together
Shi Peiyong pore contraction liquid.But the method preferably specialized beauty parlors operate, process pain is cumbersome, long-time service may have according to
Lai Xing causes pore more and more coarseer.
Summary of the invention
Place in view of the deficiency of the prior art is dispelled being sprayed of blackhead the present invention provides a kind of mild oil-control, can
To be sprayed directly on to face, it will be blocked in the blackhead dissolution exudation of pore, while can control the secretion of grease, reach skin grease
The effect of balance.It can be used for a long time, it is easy to operate, there are sterilization, anti-inflammatory, corrosion-resistant effect, play the improvement colour of skin, restores strong
The skin of health vigor.
To achieve the purpose of the present invention, the technical solution adopted by the present invention are as follows: a kind of mild oil-control is dispelled being sprayed of blackhead, and is wrapped
Component containing following parts by weight: 0.5-1 parts of arginine, 0.1-0.2 parts of phytic acid, 0.1-0.8 parts of silver oxide, EDTA-
Na20.01-0.08 parts.
Preferably, the mild oil-control is dispelled being sprayed of blackhead, and is contained the following parts by weight: 0.7-0.9 parts of arginine,
0.15-0.18 parts of phytic acid, 0.3-0.6 parts of silver oxide, EDTA-Na20.03-0.06 parts.
Preferably, the mild oil-control is dispelled being sprayed of blackhead, and is contained the following parts by weight: 0.75 part of arginine, flesh
0.16 part of six phosphoric acid of alcohol, 0.52 part of silver oxide, EDTA-Na20.05 part.
The arginine that the present invention uses is also known as Argine Monohydrochloride or L-arginine, and molecular formula is C6H14N4O2, main using life
The production of object zymotechnique, aqueous solution are in strong basicity.Arginine is the very important amino acid of human body, with strengthen immunity
Effect.Skin water holding capacity can be improved with cutin-softening layer in cosmetics, improved dry coarse;It can replace completely simultaneously
For triethanolamine, play the role of buffered pH value.
Phytic acid is also known as phytic acid, is a kind of organic phosphorus acid compounds extracted from plant seed, and molecular formula is
C6H18O24P6, aqueous solution is in highly acid.There are in the nucleated red blood cell of animal, can promote releasing for oxygen in oxyhemoglobin for phytic acid
It puts, improves erythrocyte function;Simultaneously the itself nutriment beneficial to human body, phytic acid hydrolysate in human body be inositol and
Phosphoric acid, the former has anti-aging effects, and the latter is human body cell important component;And phytic acid is to most metal ions
There is an extremely strong complexing power, what each molecule can provide that six pairs of hydrogen atoms make free radical electronically forms rock-steady structure.Thus it plants
The application of acid is very extensive, and the softening agent etc. of chelating agent, antioxidant, antistaling agent, water can be made in cosmetics.
Silver oxide molecular formula is Ag2O can be hydrolyzed into silver ion and hydroxide ion in water, and silver ion can rise
The effect of to antibacterial anti-inflammatory.EDTA-Na2It is a kind of good compounding agent in chemistry for disodium ethylene diamine tetraacetate, there are six it
The complex of coordination atom, formation is called chelate.
Mild oil-control is prepared as described above the present invention also provides one kind to dispel the spraying preparation method of blackhead, including following step
It is rapid:
(1) by EDTA-Na2, water be added to after emulsion pot and be warming up to 80-90 DEG C, stir 15min;
(2) after the Material uniformity of the step (1), start to be cooled to 50-60 DEG C, arginine is added, stirs at a slow speed
Mix 15min;
(3) continue to be cooled to 40-45 DEG C, sequentially add phytic acid and silver oxide, mix slowly to even one transparent material
Body, after being cooled to 38 DEG C, filtering takes the dish out of the pot, and is dispelled being sprayed of blackhead with the aseptic packaging of nozzle pot up to the mild oil-control.
Preferably, the emulsion pot of the step (1) is warming up to 85 DEG C;The EDTA-Na2Parts by weight be 0.05 part.
Preferably, the temperature in the step (2) is down to 55 DEG C;The arginic parts by weight are 0.75 part.
Preferably, the temperature in the step (3) is down to 45 DEG C;The parts by weight of the phytic acid are 0.16 part, oxygen
The parts by weight for changing silver are 0.52 part.
Beneficial effects of the present invention: of the invention can will block the blackhead dissolution exudation of pore by spraying, while can control
The secretion of liquefaction rouge;And it is easy to operate, do not stimulate mildly;Long-time service has effects that antibacterial anti-inflammatory, so as to repair
Impaired skin, improves the colour of skin, has the function that oil-water balance.
Detailed description of the invention
Fig. 1 is 4 chick chorioallantoic membrane vascular testing experimental result schematic diagram of the embodiment of the present invention.
Fig. 2 is 5 chick chorioallantoic membrane vascular testing experimental result schematic diagram of comparative example of the present invention.
Specific embodiment
For more concise displaying technical solution of the present invention, objects and advantages, combined with specific embodiments below
The present invention is described in further detail.
Table 1: the formula table of embodiment 1-5 and comparative example 1-4
Comparative example 5
Comparative example 5 is that a kind of blackhead of commercial like product of the invention exports liquid, main component are as follows: its formulation weight
Number be 6 parts of 'alpha '-hydroxy acids, 1 part of chitosan, 2 parts of glycerol, 1.5 parts of 1,2- hexylene glycol, 0.5 part of sodium lactate, 0.4 part of xanthan gum,
88.6 parts of deionized water.
Embodiment 6
It dispels the spraying preparation method of blackhead, the described method comprises the following steps the present embodiment provides a kind of mild oil-control:
(1) by the EDTA-Na of 0.05 part of parts by weight2It is added to after emulsion pot with water and is warming up to 85 DEG C, stir 15min;
(2) after the Material uniformity of the step (1), start to be cooled to 55 DEG C, the essence of 0.75 part of parts by weight is added
Propylhomoserin mixes slowly 15min;
(3) continue to be cooled to 45 DEG C, sequentially add the phytic acid of 0.16 part of parts by weight and the oxygen of 0.52 part of parts by weight
Change silver, mixes slowly to even one transparent Material, after being cooled to 38 DEG C, filtering takes the dish out of the pot, with the aseptic packaging of nozzle pot up to the temperature
It dispels being sprayed of blackhead with oil-control.
By the sample of embodiment 1-5 and comparative example 1-5, (wherein embodiment 1-5 and comparative example 1-4 are all made of embodiment 6
Preparation method) effect assessment is carried out, experimental method is as follows:
One, irritation is tested
Test analysis is carried out to the irritation of embodiment 1-5 and comparative example 1-5 sample, test item is chicken embryo villus allantois
The experiment of film blood vessel, standards of grading have: reactionless, ghost blood vessel, capillary damage, pole slight bleeding, slight bleeding, extremely slightly
Bleeding, hyporrhea, moderate bleeding and severe haemorrhage.The judgement of chick chorioallantoic membrane blood vessel experimental result is referring to NC value, NC value
0-10 points, wherein 0-2 points of irritability is reacted;2-3 points of minimal irritation is reacted;3-5 divides moderate stimulate the reaction;5-10 is seriously stimulated instead
It answers.Experimental result such as the following table 2:
Table 2: irritation test result of the present invention
As shown in Table 2, the spraying NC value of blackhead of dispelling of the invention 0-2/, in chick chorioallantoic membrane blood vessel
Chicken is (such as Fig. 1) without any adverse reactions in experiment, the NC value of comparative example 5 3-5/, have moderate stimulate the reaction to chicken embryo,
There is slight bleeding (such as Fig. 2), illustrates that of the invention being sprayed does not stimulate mildly.
Two, it dispels blackhead measure of merit
1, oil-control is dispelled the effect and Comfort Evaluation of blackhead
Analysis is compared to the dispel effect of blackhead of embodiment 1-5 and comparative example 1-5 sample oil-control, chooses 100 noses
There is the patient of blackhead, the age at 20-50 years old, is randomly divided into 10 groups, and every group of 10 people use embodiment 1-5 and comparative example 1-5 respectively
Sample.Each group volunteer by nose it is clean after, be sprayed on nose by spraying for every group, then stick layer of non-woven fabric, stand 15
After minute, non-woven fabrics is removed, cleans nose with clear water, observes the oil quantity and blackhead amount of each volunteer's nose.Judgement is effective
Standard be use after, volunteer's nose does not have grease and blackhead;After judging the standard to take effect as use, volunteer's nose has few
The grease and blackhead of amount;After judging invalid standard for use, volunteer's nose has apparent grease and blackhead.Simultaneously to implementation
The dispel comfort level of blackhead of example 1-5 and comparative example 1-5 sample oil-control is evaluated, and is divided into: strong tingling sensation, slightly tingling sensation and compared with
It is comfortable.Blackhead effect of dispelling scores total score 0-10 points, and wherein 0-1 divides invalid;2-5 points are taken effect;6-10 points effective.Experiment test knot
Fruit such as the following table 3 and 4:
3. present invention of table dispels blackhead effect assessment table
The oil-control of the present invention of table 4. is dispelled the Comfort Evaluation table of blackhead
By table 3,4 it is found that embodiment 1-5 dispel the scoring of blackhead effect 6-10/, it is seen that have and good dispel
Blackhead effect;Since comparative example 1-4 lacks some of them ingredient, the effect of pore cleanser is not achieved, illustrates inventive formulation
Component carry out compatibility have synergy, have effects that blackhead of dispelling;Find out that the commercial like product of comparative example 5 has from result
Slightly tingling sensation, also effect not of the invention is good for the effect for blackhead of dispelling.Illustrate that the present invention can be molten by the blackhead for blocking pore
Solution exudation;It is easy to operate, do not stimulate mildly, long-time service have the effect of antibacterial anti-inflammatory.
2, it dispels the effect of blackhead to different degrees of blackhead patient
To slight blackhead patient, uniformly it is sprayed on what the present invention sprayed around face, especially nose and the wing of nose by spraying,
After complete wetting face, the appearance of milky grease is had, is directly rinsed well with clear water.
Centering severe blackhead patient is sprayed what the present invention sprayed and is sprayed on around nose and the wing of nose after face is cleaned, and pastes
On wetted nose paster, take nose paster off after ten minutes.
By using product of the invention, the observation period three months;After 2-3 days, slight blackhead patient can dispel substantially;4-10
It, mild or moderate blackhead patient can cure;11-45 days, middle severe blackhead patient can cure successively;Because of skin situation itself after healing
Individual blackhead patients have rebound phenomenon, and recurrence blackhead patient is used continuously three months, all basic to cure.In the above-mentioned observation period,
Spraying not stimulate mildly, have no adverse reaction appearance, while having oil-control effect.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
It cannot therefore be construed as limiting the scope of the patent.It should be pointed out that coming for those of ordinary skill in the art
It says, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to protection of the invention
Range.Therefore, the scope of protection of the patent of the invention shall be subject to the appended claims.
Claims (7)
1. a kind of mild oil-control is dispelled, blackhead is sprayed, which is characterized in that is contained the following parts by weight: 0.5-1 parts of arginine,
0.1-0.2 parts of phytic acid, 0.1-0.8 parts of silver oxide, EDTA-Na20.01-0.08 parts.
2. mild oil-control as described in claim 1 is dispelled, blackhead is sprayed, which is characterized in that is contained the following parts by weight:
0.7-0.9 parts of arginine, 0.15-0.18 parts of phytic acid, 0.3-0.6 parts of silver oxide, EDTA-Na20.03-0.06 parts.
3. oil-control as described in claim 1 mild is dispelled, blackhead is sprayed, which is characterized in that the mild oil-control is dispelled the spray of blackhead
Mist contains the following parts by weight: 0.75 part of arginine, 0.16 part of phytic acid, 0.52 part of silver oxide, EDTA-
Na20.05 part.
It prepares mild oil-control as described in any one of claims 1-3 4. a kind of and dispels the spraying preparation method of blackhead, feature exists
In, comprising the following steps:
(1) by EDTA-Na2, water be added to after emulsion pot and be warming up to 80-90 DEG C, stir 15min;
(2) after the Material uniformity of the step (1), start to be cooled to 50-60 DEG C, arginine is added, mixes slowly
15min;
(3) continue to be cooled to 40-45 DEG C, sequentially add phytic acid and silver oxide, mix slowly to even one transparent Material, drop
To after 38 DEG C, filtering takes the dish out of the pot temperature, is dispelled being sprayed of blackhead with the aseptic packaging of nozzle pot up to the mild oil-control.
5. preparation method as claimed in claim 4, which is characterized in that the emulsion pot of the step (1) is warming up to 85 DEG C;It is described
EDTA-Na2Parts by weight be 0.05 part.
6. preparation method as claimed in claim 4, which is characterized in that the temperature in the step (2) is down to 55 DEG C;The essence
The parts by weight of propylhomoserin are 0.75 part.
7. preparation method as claimed in claim 4, which is characterized in that the temperature in the step (3) is down to 45 DEG C;The flesh
The parts by weight of six phosphoric acid of alcohol are 0.16 part, the parts by weight of silver oxide are 0.52 part.
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CN201910188818.3A CN109893462B (en) | 2019-03-13 | 2019-03-13 | Mild oil-controlling blackhead-removing spray and preparation method thereof |
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CN201910188818.3A CN109893462B (en) | 2019-03-13 | 2019-03-13 | Mild oil-controlling blackhead-removing spray and preparation method thereof |
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US20050031547A1 (en) * | 2003-08-04 | 2005-02-10 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
CN105228585A (en) * | 2013-05-16 | 2016-01-06 | 帝斯曼知识产权资产管理有限公司 | Topical compositions |
CN105250189A (en) * | 2015-11-24 | 2016-01-20 | 广州市花安堂生物科技有限公司 | Acne treatment essence cream and preparing method thereof |
CN105434233A (en) * | 2015-12-08 | 2016-03-30 | 广州市花安堂生物科技有限公司 | Keratin repair essence and preparation method thereof |
CN106572966A (en) * | 2014-05-13 | 2017-04-19 | 尤尼维尔肌肤公司 | Extemporaneous cosmetic and/or dermatological preparations |
CN107582428A (en) * | 2017-09-21 | 2018-01-16 | 广州添意时企业管理有限公司 | One kind is dispelled blackhead purification frost and preparation method thereof |
CN108542862A (en) * | 2018-05-31 | 2018-09-18 | 苏州蔻美新材料有限公司 | A kind of preparation method for blackhead cleaning spraying of dispelling |
CA3008110A1 (en) * | 2017-06-14 | 2018-12-14 | Counter Brands, Llc | Skin mimicking emulsion |
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2019
- 2019-03-13 CN CN201910188818.3A patent/CN109893462B/en active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
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US20050031547A1 (en) * | 2003-08-04 | 2005-02-10 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
CN105228585A (en) * | 2013-05-16 | 2016-01-06 | 帝斯曼知识产权资产管理有限公司 | Topical compositions |
CN106572966A (en) * | 2014-05-13 | 2017-04-19 | 尤尼维尔肌肤公司 | Extemporaneous cosmetic and/or dermatological preparations |
CN105250189A (en) * | 2015-11-24 | 2016-01-20 | 广州市花安堂生物科技有限公司 | Acne treatment essence cream and preparing method thereof |
CN105434233A (en) * | 2015-12-08 | 2016-03-30 | 广州市花安堂生物科技有限公司 | Keratin repair essence and preparation method thereof |
CA3008110A1 (en) * | 2017-06-14 | 2018-12-14 | Counter Brands, Llc | Skin mimicking emulsion |
CN107582428A (en) * | 2017-09-21 | 2018-01-16 | 广州添意时企业管理有限公司 | One kind is dispelled blackhead purification frost and preparation method thereof |
CN108542862A (en) * | 2018-05-31 | 2018-09-18 | 苏州蔻美新材料有限公司 | A kind of preparation method for blackhead cleaning spraying of dispelling |
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