CN109893083A - Objective human eye wavefront aberration measurement system and method - Google Patents
Objective human eye wavefront aberration measurement system and method Download PDFInfo
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Abstract
The invention discloses an objective human eye wavefront aberration measuring system and method. The system comprises a beacon light emitting subsystem, a beacon light source and a light source module, wherein the beacon light emitting subsystem is used for providing a beacon light source for human eye aberration measurement; the imaging subsystem is used for acquiring a far field image of the beacon light imaged on the fundus; the human eye aberration correction subsystem is used for correcting human eye wavefront aberration; the wavefront corrector is based on a beacon light image obtained by the imaging camera; the far field image based on the beacon light controls the wavefront corrector to realize wavefront correction by using an optimization algorithm, and then wavefront aberration information of the human eyes is obtained by using a wavefront corrector influence function and a wavefront reconstruction matrix which are calibrated in advance. The invention has the beneficial effects that: the human eye defocus and astigmatism can be corrected simultaneously through the wavefront corrector, the large dynamic range aberration measurement is realized, and the crowd application range is expanded; the human eye wavefront aberration optimization algorithm based on the beacon light far field image can quickly iterate to realize wavefront correction and reduce the requirement on human eye stability; the optical system has no focusing moving part, and is simple and easy to realize.
Description
Technical field
The present invention relates to the wave-front optical aberration measurement correlative technology fields of no wavefront sensing, refer in particular to a kind of objective human eye wave
Preceding aberration measurement system and method.
Background technique
Human eye is as typical optical system, the aberration containing Multiple components, and defocus and astigmatism are referred to as ametropia, school
Just human eye is ametropia can bring significantly improving for visual performance.Measuring the ametropic instrument of human eye mainly includes that subjectivity is tested
Light instrument and objective optometry instrument, patent CN2071054U, CN103300813A, CN1194131A, US4848895, US5844660 etc.
Describe the subjective and objective optometry method of a variety of human eyes, quickly can accurately obtain the ametropia information of human eye, be clinical research and
Optometry provides foundation with mirror etc..With the intensification that researcher recognizes human eye dioptric system, find in human eye aberration in addition to everybody
Outside known defocus and astigmatism, there is also more complicated ingredients, are referred to as higher order aberratons.Hartmann's wavefront sensing technique is people
Most common technology in eye higher order aberratons measurement.United States Patent (USP) US5777719A, Chinese patent CN1701756A and
CN101926640A describes the adaptive optics system for improving human eye visual function and retinal images resolution ratio, using Hartmann
Wavefront sensor has carried out precise measurement to human eyes wave-front optical aberration, and is corrected by wave-front corrector to aberration, demonstrates
The accuracy of measurement.United States Patent (USP) US6575572B2, US6439720B1, US6550917B1, US7419264B1, Chinese patent
CN101803906, CN106163378A, CN105496351A etc. report a variety of Hartmann's wavefront sensing techniques in human eye aberration
Prioritization scheme in measurement.It is limited to the contradiction in Hartmann's wavefront sensing technique between measurement accuracy and measurement dynamic range,
In the design of actual aberration measurement instrument, needs to increase low order aberration compensation device, increase the complexity and control of system
Difficulty;And in existing patent, low order compensation has also compensated only for defocus, for high astigmatism human eye, relies on Hartmann's wavefront sensing
The dynamic range of device is difficult to ensure measurement accuracy.
Summary of the invention
The present invention is to overcome and rise in the prior art for the aberration amplitude faced in living human eye wave-front optical aberration measurement
Volt is big and human eye stability is insufficient, provide a kind of no wavefront sensing, the objective human eyes wave-front optical aberration based on aberration correction surveys
Measure system and method.
To achieve the goals above, the invention adopts the following technical scheme:
A kind of objective human eyes wave-front optical aberration measurement system, including beacon light emitting subsystem, imaging subsystems, human eye aberration
Subsystem, spectroscope and computer are corrected, the beacon light emitting subsystem and imaging subsystems pass through spectroscope and human eye
The docking of aberration correction subsystem, the beacon light emitting subsystem includes beacon light source, collimation lens and beacon light bar, described
Beacon light source pass sequentially through collimation lens and beacon light bar is docked with spectroscope, the imaging subsystems include imaging len
And image camera, the image camera are docked by imaging len with spectroscope, the human eye aberration corrects subsystem packet
Include wave-front corrector, the first aperture matching lens, the second aperture matching lens and filtering light bar, the spectroscope and wavefront school
Positive device docking, the wave-front corrector matches lens by the first aperture and the second aperture matches lens and docks with human eye, institute
The filtering light bar stated is placed between the first aperture matching lens and the second aperture matching lens, the image camera and wavefront school
Positive device is connect with computer.
Beacon light emitting subsystem provides beacon light source for human eye aberration measurement;Imaging subsystems, for acquiring beacon beam
In the far field image of fundus imaging;Human eye aberration corrects subsystem, for correcting human eyes wave-front optical aberration;Wave-front corrector be based at
As the beacon light image that camera obtains, human eye defocus and astigmatism can be corrected by wave-front corrector simultaneously, realize Larger Dynamic range
The measurement of aberration expands crowd's scope of application.Without focusing movements component in optical system, system is simple, it is easy to accomplish.
Preferably, the beacon light bar is annular light bar or paraxonic light bar, the beacon light source uses near-infrared
Wave band.
Preferably, the beacon light source is 800nm-1000nm.
Preferably, the image camera is one of CCD, CMOS, PMT, photoelectric tube, photodiode.Imaging
Camera is for acquiring beacon beam in the far field image of eyeground retroreflection.
Preferably, the wave-front corrector be liquid crystal corrector, micro electronmechanical distorting lens, Mciomachined membrane deformable mirror,
One of double piezoelectric ceramic distorting lens, liquid distorting lens.
The present invention also provides a kind of objective human eyes wave-front optical aberration measurement methods, specifically comprise the following steps:
(1) beacon light source issue beacon beam, after being collimated by collimation lens, through beacon light bar, spectroscope, wave-front corrector,
First aperture matches lens and the second aperture matches lens, focuses on retina through dioptric system into human eye;
(2) back reflected laser of beacon beam is imaged on image camera along backtracking to spectroscope by imaging len, meter
The machine-readable beacon beam far field image for taking image camera is calculated, calculating target function simultaneously calls optimizing algorithm control wave-front corrector to complete
The correction of human eyes wave-front optical aberration;
(3) after the completion of correcting, wavefront surface type out is restored according to the actuator voltage value of wave-front corrector, by wavefront reconstruction square
Every zernike coefficient that battle array obtains human eyes wave-front optical aberration completes the measurement process of human eyes wave-front optical aberration.
Wave-front corrector progress wavefront correction is then controlled with wavefront measurement is based in traditional human eye adaptive optics system
Difference, the present invention is based on the far field image of beacon beam control wave-front correctors to realize wavefront correction using optimizing algorithm, then sharp
Human eyes wave-front optical aberration information is obtained with the wave-front corrector influence function and wavefront reconstruction matrix demarcated in advance.Pass through wavefront correction
Device can correct human eye defocus and astigmatism simultaneously, realize the measurement of Larger Dynamic range aberration, expand crowd's scope of application;Based on beacon
The human eyes wave-front optical aberration optimizing algorithm of light far field image, can iteratively faster realize wavefront correction, reduce human eye stability requirement.
Preferably, in step (2), the objective function be from image sharpness function, far field image mean radius,
The one kind chosen in the peak value Si Telieer ratio of far field.
Preferably, the optimizing algorithm is from simulated annealing, simplex method, schema extraction in step (2)
The one kind chosen in algorithm, random paralleling gradient descent algorithm.
The beneficial effects of the present invention are: human eye defocus and astigmatism can be corrected simultaneously by wave-front corrector, Larger Dynamic is realized
The measurement of range aberration expands crowd's scope of application;Human eyes wave-front optical aberration optimizing algorithm based on beacon beam far field image, can be fast
Fast iteration realizes wavefront correction, reduces human eye stability requirement;Without focusing movements component in optical system, system is simple, is easy to
It realizes.
Detailed description of the invention
Fig. 1 is structural schematic diagram of the invention;
Fig. 2 is the beacon beam obtained in the present invention for camera before 20 aberrations progress SPGD optimal-search controls before subject human eye
Image;
Fig. 3 is the beacon beam obtained in the present invention for camera after 20 aberrations progress SPGD optimal-search controls before subject human eye
Image;
Fig. 4 is the relational graph of remaining wave front aberration and the number of iterations in the present invention;
Fig. 5 is the wave front aberration zernike coefficient restored in the present invention and the comparison diagram of human eye aberration zernike coefficient.
In figure: 1. beacon light sources, 2. collimation lenses, 3. beacon light bars, 4. spectroscopes, 5. wave-front correctors, 6. first holes
Diameter matches lens, 7. filtering light bars, and 8. second apertures match lens, 9. human eyes, 10. imaging lens, 11. image cameras, 12. meters
Calculation machine.
Specific embodiment
The present invention will be further described with reference to the accompanying drawings and detailed description.
In embodiment as described in Figure 1, a kind of objective human eyes wave-front optical aberration measurement system, including beacon light emitting subsystem
System, imaging subsystems, human eye aberration correction subsystem, spectroscope 4 and computer 12, beacon light emitting subsystem and imaging subsystem
For system by spectroscope 4 and human eye aberration syndrome system docking, beacon light emitting subsystem includes beacon light source 1, collimation lens 2
With beacon light bar 3, beacon light source 1 passes sequentially through collimation lens 2 and beacon light bar 3 is docked with spectroscope 4, and imaging subsystems include
Imaging len 10 and image camera 11, image camera 11 are docked by imaging len 10 with spectroscope 4, and human eye aberration corrects subsystem
System includes wave-front corrector 5, the first aperture matching lens 6, the second aperture matching lens 8 and filtering light bar 7, spectroscope 4 and wave
Preceding corrector 5 docks, and wave-front corrector 5 matches lens 6 by the first aperture and the second aperture matches lens 8 and docks with human eye 9,
Filtering light bar 7 is placed between the first aperture matching lens 6 and the second aperture matching lens 8, image camera 11 and wave-front corrector 5
It is connect with computer 12.Beacon light bar 3 is annular light bar or paraxonic light bar, and beacon light source 1 uses near infrared band.Beacon beam
Source 1 is 800nm-1000nm.Image camera 11 is one of CCD, CMOS, PMT, photoelectric tube, photodiode.Wavefront correction
Device 5 be liquid crystal corrector, micro electronmechanical distorting lens, Mciomachined membrane deformable mirror, double piezoelectric ceramic distorting lens, in liquid distorting lens
It is a kind of.
The present invention also provides a kind of objective human eyes wave-front optical aberration measurement methods, specifically comprise the following steps:
(1) beacon light source 1 issues beacon beam, after being collimated by collimation lens 2, through beacon light bar 3, spectroscope 4, wavefront correction
Device 5, the first aperture matching lens 6 and the second aperture match lens 8, focus on retina through dioptric system into human eye 9;
(2) back reflected laser of beacon beam is along backtracking to spectroscope 4, by imaging len 10 on image camera 11 at
Picture, computer 12 read the beacon beam far field image of image camera 11, and calculating target function simultaneously calls optimizing algorithm to control wavefront
The correction of the completion human eyes wave-front optical aberration of corrector 5;Objective function is from image sharpness function, far field image mean radius, far field
The one kind chosen in peak value Si Telieer ratio;Optimizing algorithm be from simulated annealing, simplex method, schema extraction algorithm, with
The one kind chosen in machine parallel gradient descent algorithm;This is the process of an iteration, until wave-front corrector 5 corrects human eye wavefront
Aberration to beacon beam far field image reaches ideal situation.
(3) after the completion of correcting, wavefront surface type out is restored according to the actuator voltage value of wave-front corrector 5, by wavefront reconstruction
Every zernike coefficient that matrix obtains human eyes wave-front optical aberration completes the measurement process of human eyes wave-front optical aberration.
It is using image sharpness as objective function, using stochastic parallel gradient descent (SPGD) algorithm as optimizing algorithm below
Example, to illustrate human eyes wave-front optical aberration correction course and zernike coefficient recuperation.
Objective function first are as follows:
Wherein I (x, y) is light intensity value of the beacon light image at point (x, y).Human eyes wave-front optical aberration only needs under normal circumstances
20 are corrected before Zernike polynomials fitting.Objective function J is the function of control vector a=(a3, a4, a5 ..., a20).In order to make mesh
Scalar functions reach maximum, we carry out optimizing to it using bilateral disturbance SPGD algorithm, and the m+1 times iterative process is as follows:
It generates random perturbation △ a=(△ a3, △ a4, △ a5 ..., △ a20), obtains interim control vector a+=a m+ △ a, a-=a
m-△a;Interim control voltage V+, V- are calculated by temporarily controlling vector a+, a-, drives first wave after control circuit is amplified
Preceding corrector generates phase change, and image camera 11 obtains interim beacon light image and calculates transient target function J (a+) and J
(a-);Control vector a m+1=a m+ λ (△ J) △ a is updated, wherein λ is gain coefficient, △ J=J (a+)-J (a-).The iteration
Process persistently carries out no longer becoming larger until objective function or until iteration predetermined number of times.
After the completion of correction, according to the actuator voltage value V of wave-front corrector 5iIt is each with the calibrated wave-front corrector 5 of system
Driver influence function fi(x, y) can fit human eye wavefront at this time
Particularly, when wave-front corrector 5 is liquid crystal corrector, each driver influence function is linear response, can directly fit people
Before glances;When the response of 5 driver of wave-front corrector is in nonlinear characteristic, need to measure between control voltage and corrector face type
Non-linear relation curve, by control voltage calculate wave-front corrector 5 compensate wavefront when be modified.Human eyes wave-front optical aberration
After the completion of recovery, human eyes wave-front optical aberration is completed by every zernike coefficient that wavefront reconstruction matrix calculates human eye aberration
Measurement process.Particularly, when system and method measurement ametropic for human eye, it is only necessary to restore preceding 5 Ze Nike systems
Number.
Fig. 2 and Fig. 3 gives for camera before and after 20 progress SPGD optimal-search controls before a certain specific human eyes wave-front optical aberration
The beacon light image of acquisition, Fig. 2 are without carrying out beacon light image when aberration correction, after Fig. 3 is SPGD optimal-search control
Beacon light image.In this example, residual wavefront aberrations root mean square is stablized at 0.1 micron, as shown in Figure 3 at iteration 200 times.Pass through
The human eye aberration zernike coefficient and human eye actual wavefront aberration coefficients that wavefront reconstruction matrix calculates are completely the same, the two root mean square
Error is 0.024 micron, as shown in figure 4, illustrating that this method can accurately measure the wave front aberration of human eye.
Claims (8)
1. a kind of objective human eyes wave-front optical aberration measurement system, characterized in that including beacon light emitting subsystem, imaging subsystems,
Human eye aberration corrects subsystem, spectroscope (4) and computer (12), and the beacon light emitting subsystem and imaging subsystems are logical
Spectroscope (4) and human eye aberration syndrome system docking are crossed, the beacon light emitting subsystem includes beacon light source (1), standard
Straight lens (2) and beacon light bar (3), the beacon light source (1) pass sequentially through collimation lens (2) and beacon light bar (3) and divide
Light microscopic (4) docking, the imaging subsystems include imaging len (10) and image camera (11), the image camera (11)
It is docked by imaging len (10) with spectroscope (4), the described human eye aberration correction subsystem includes wave-front corrector (5), the
One aperture matches lens (6), the second aperture matching lens (8) and filtering light bar (7), the spectroscope (4) and wavefront correction
Device (5) docking, the wave-front corrector (5) pass through the first aperture matching lens (6) and the second aperture matching lens (8) and people
Eye (9) docking, the filtering light bar (7) are placed between the first aperture matching lens (6) and the second aperture matching lens (8),
The image camera (11) and wave-front corrector (5) is connect with computer (12).
2. a kind of objective human eyes wave-front optical aberration measurement system according to claim 1, characterized in that the beacon light bar
It (3) is annular light bar or paraxonic light bar, the beacon light source (1) uses near infrared band.
3. a kind of objective human eyes wave-front optical aberration measurement system according to claim 2, characterized in that the beacon light source
It (1) is 800nm-1000nm.
4. a kind of objective human eyes wave-front optical aberration measurement system according to claim 1 or 2 or 3, characterized in that it is described at
As camera (11) are one of CCD, CMOS, PMT, photoelectric tube, photodiode.
5. a kind of objective human eyes wave-front optical aberration measurement system and method according to claim 1 or 2 or 3, characterized in that institute
The wave-front corrector (5) stated be liquid crystal corrector, micro electronmechanical distorting lens, Mciomachined membrane deformable mirror, double piezoelectric ceramic distorting lens,
One of liquid distorting lens.
6. a kind of objective human eyes wave-front optical aberration measurement method, characterized in that specifically comprise the following steps:
(1) beacon light source (1) issues beacon beam, after collimation lens (2) collimation, through beacon light bar (3), spectroscope (4), wavefront
Corrector (5), the first aperture matching lens (6) and the second aperture matching lens (8), focus into human eye (9) through dioptric system
In retina;
(2) back reflected laser of beacon beam is along backtracking to spectroscope (4), by imaging len (10) on image camera (11)
Imaging, computer (12) read the beacon beam far field image of image camera (11), and calculating target function simultaneously calls optimizing algorithm control
Wave-front corrector (5) processed completes the correction of human eyes wave-front optical aberration;
(3) after the completion of correcting, wavefront surface type out is restored according to the actuator voltage value of wave-front corrector (5), by wavefront reconstruction square
Every zernike coefficient that battle array obtains human eyes wave-front optical aberration completes the measurement process of human eyes wave-front optical aberration.
7. a kind of objective human eyes wave-front optical aberration measurement method according to claim 6, characterized in that in step (2), institute
The objective function stated is the one kind chosen from image sharpness function, far field image mean radius, far field peak value Si Telieer ratio.
8. a kind of objective human eyes wave-front optical aberration measurement system and method according to claim 6 or 7, characterized in that in step
Suddenly in (2), the optimizing algorithm is from simulated annealing, simplex method, schema extraction algorithm, stochastic parallel gradient descent
The one kind chosen in algorithm.
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CN111772574A (en) * | 2020-06-06 | 2020-10-16 | 宁波明星科技发展有限公司 | Method and device for eliminating defocusing during wavefront aberration measurement |
CN112043232A (en) * | 2020-09-27 | 2020-12-08 | 中国科学院光电技术研究所 | Objective measuring apparatu of adaptive optics people's eye scattering |
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