CN109865017A - A kind of paste and preparation method thereof of easy-to-use treatment acne - Google Patents
A kind of paste and preparation method thereof of easy-to-use treatment acne Download PDFInfo
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- 206010000496 acne Diseases 0.000 title claims abstract description 67
- 208000002874 Acne Vulgaris Diseases 0.000 title claims abstract description 63
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 30
- 206010004542 Bezoar Diseases 0.000 claims abstract description 18
- 244000153234 Hibiscus abelmoschus Species 0.000 claims abstract description 18
- 244000157790 Buglossoides arvense Species 0.000 claims abstract description 16
- 235000004256 Buglossoides arvense Nutrition 0.000 claims abstract description 16
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- 235000008081 Rheum officinale Nutrition 0.000 claims abstract description 16
- 239000001525 mentha piperita l. herb oil Substances 0.000 claims abstract description 16
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- 239000000470 constituent Substances 0.000 claims abstract description 12
- 239000003814 drug Substances 0.000 claims description 49
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Abstract
The invention discloses a kind of paste and preparation method thereof for treating acne, the active constituent of the paste is prepared by the raw material components of following parts by weight: 3~15 parts of Asian puccoon, 2~15 parts of Fructus Forsythiae, 1~5 part of Radix Salviae Miltiorrhizae, 1~10 part of Cortex Phellodendri, 1~10 part of rhizoma atractylodis, 1~15 part of chaulmoogra, 1~10 part of the root of Dahurain angelica, 2~10 parts of kuh-seng, 1~10 part of the root bark of white mulberry, 1~10 part of spina gleditsiae, 1~10 part of dandelion, 1~5 part of rheum officinale, 3~10 parts of peppermint oil, 0.1~0.8 part of Moschus, 0.1~0.5 part of cow-bezoar.Paste of the invention has effects that clearing heat and detoxicating, eliminating toxic is outgoing, eliminating toxic dampness and heat, can be and effective in cure to the acne of different constitution crowds, each period different pathogeny with effective antiinflammatory, antibacterial, moisturizing and skin care, and has no toxic side effect.The paste is innovatively filled in lipstick shape packing container by the present invention so that product it is beautiful and generous, convenient for carrying, easy to use, can be applied directly to affected part, when smearing, will not make finger and other skin parts dirty.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine, and in particular to a kind of paste of easy-to-use treatment acne and its
Preparation method.
Background technique
Acne is a kind of chronic inflammatory skin of pilosebaceous unit, common people be called " pimple ",
" small pox ", dermatology are known as acne vulgaris, furuncle etc..Preference betides teenager, also betides in Chinese middle-aged adults, shows as inflammation
The pleomorphism skin lesions such as property papule, blackhead, Whiteheads, tubercle, tumour.From the beginning of for acne, there are Whiteheads and blackhead powder
Two kinds of thorn, includes cutin and sebum.Whiteheads are also known as closed comedones, body by the area that acne are influenced most serious be face,
Neck, chest, shoulder and back, this is because there are many sebaceous glands in these regions.These bodies of gland have sebum production in skin follicle
Raw, this is a kind of oily matter, plays the role of lubricating hair and skin.Sometimes, excessive sebum can block pore, be
Bacterium, which grows up strong and sturdy, creates an ideal environment, so as to cause the development of inflammation and acne.
Acne is because its course of disease is long, recur repeatedly, may can gently can leave pigmentation, recess even scar again, after recession
Trace to influence the image of patient, and then influences its work, study, daily life, or even influences psychology, is become by common people
" beautiful worry ".Therefore, the drug for treating acne has large market needs and commercial value.Acne is treated on the market
Product is numerous, be divided into antibacterial, steroids, physiotherapy etc. it is a variety of, dosage form has ointment, spray, physics illumination meter etc., respectively
The different principle formed for a variety of acnes such as bacterium, endocrine disorder；It is difficult for the crowd of different constitutions, the acne of different times
To obtain the therapeutic effect of generality.
Remove the product of acne or anti-acne, such as paste, the liquid spray agent of Chinese medicine or western medicine composition on the market at present
Type, it usually needs smear or be sprayed on affected part, there are the deficiency in some applications, if any use process in influence beautiful, have
Smearing it is inconvenient and be easy to make other skin parts such as finger dirty, what is had is not readily portable, such as band is boarded a plane, public place is equal
It is limited；And physical therapies, the equipment such as many illumination are huge, need professional institution to be operated, are not easy to promotion and application, and
The therapeutic effect of the above various existing medicaments is not good enough.
In conclusion how to prepare a kind of adaptable, using convenient and good therapeutic effect treatment acne drug, still
It is so those skilled in the art's technical problem urgently to be solved at present.
Summary of the invention
It is an object of the present invention to provide a kind of paste of easy-to-use treatment acne, can effectively treat not
With the acne in each period of constitution crowd.The present inventor is former to the understanding of pathogenesis of acne mechanism and treatment based on motherland's medicine
Then, it is achieved with reference to modern pharmacological research, according to clearing heat and detoxicating, activating microcirculation and removing stasis medicinal, the principles of formulating prescriptions of dispersing swelling and dissipating binds, is combined into the present invention
The raw materials of traditional Chinese medicine composition component formula of paste, and using the technique preparation of similar production lipstick and filling present invention treatment acne
Paste so that product of the invention it is easy to carry and smear convenience.The effective component contained in drug of the present invention can be effective
Ground improves and treats various acne.
The present invention treats herbal function, main representative ingredient and its pharmacological action of the raw materials of traditional Chinese medicine composition component of acne
Referring to following table:
Note: the Moschus in the above raw material components can be artificial or natural Moschus, and cow-bezoar can be artificial or natural cow-bezoar.
One aspect of the invention provides a kind of Chinese medicine composition for treating acne, wherein the Chinese medicine composition activity at
Divide and be prepared by the raw material components of following parts by weight: 3~15 parts of Asian puccoon, 2~15 parts of Fructus Forsythiae, 1~5 part of Radix Salviae Miltiorrhizae, Cortex Phellodendri 1~10
Part, 1~10 part of rhizoma atractylodis, 1~15 part of chaulmoogra, 1~10 part of the root of Dahurain angelica, 2~10 parts of kuh-seng, 1~10 part of the root bark of white mulberry, spina gleditsiae 1~
10 parts, 1~10 part of dandelion, 1~5 part of rheum officinale, 3~10 parts of peppermint oil, 0.1~0.8 part of Moschus, 0.1~0.5 part of cow-bezoar.
Further, in some embodiments of the above-mentioned aspect of the present invention, the active constituent of the Chinese medicine composition by
The raw material components of following parts by weight are prepared: 8~15 parts of Asian puccoon, 10~15 parts of Fructus Forsythiae, 2~4 parts of Radix Salviae Miltiorrhizae, 8~10 parts of Cortex Phellodendri,
8~10 parts of rhizoma atractylodis, 8~12 parts of chaulmoogra, 8~10 parts of the root of Dahurain angelica, 5~8 parts of kuh-seng, 8~10 parts of the root bark of white mulberry, 8~10 parts of spina gleditsiae,
3~10 parts of dandelion, 2~4 parts of rheum officinale, 5~8 parts of peppermint oil, 0.3~0.6 part of Moschus, 0.2~0.4 part of cow-bezoar.
In an embodiment of the above-mentioned aspect of the present invention, the active constituent of the Chinese medicine composition is by following parts by weight
Raw material components be prepared: 10 parts of Asian puccoon, 15 parts of Fructus Forsythiae, 3 parts of Radix Salviae Miltiorrhizae, 10 parts of Cortex Phellodendri, 8 parts of rhizoma atractylodis, 12 parts of chaulmoogra, the root of Dahurain angelica
8 parts, 10 parts of kuh-seng, 10 parts of the root bark of white mulberry, 8 parts of spina gleditsiae, 10 parts of dandelion, 3 parts of rheum officinale, 8 parts of peppermint oil, 0.5 part of Moschus, cow-bezoar
0.4 part.
Another aspect of the invention provides application of the Chinese medicine composition described above in preparation treatment acne Related product,
The product includes drug, health care product, cosmetics.
Another aspect of the present invention provides a kind of paste of easy-to-use treatment acne, wherein the paste is by this hair
Chinese medicine composition described in bright the above and sesame oil (preferably white sesameseed oil, i.e. ground sesameseed oil) and beeswax or vaseline
Composition, wherein the parts by weight of the sesame oil are 80~1000 parts, and the weight fraction ratio of sesame oil and beeswax or vaseline
For 2.5~4:1.
In some embodiments of the above-mentioned aspect of the present invention, the parts by weight of sesame oil are 300 parts in the paste, and
The weight fraction ratio of sesame oil and beeswax or vaseline is 3:1.
In some embodiments of the above-mentioned aspect of the present invention, the paste is lipstick shape paste, and method of application is similar to
The smearing of lipstick.
It is a further object to provide a kind of preparation method of the paste of easy-to-use treatment acne, it includes
Following steps:
(1) each raw material component of the above-mentioned Chinese medicine composition of corresponding parts by weight is weighed；
(2) sesame oil is heated to 130 DEG C~140 DEG C, wherein the parts by weight of the sesame oil are 80~1000 parts；
(3) beeswax or vaseline are added into the sesame oil of step (2) and makes it dissolve, wherein sesame oil and beeswax or all
The weight fraction ratio of intellectual circle is 2.5~4:1；
(4) by above-mentioned weighed Asian puccoon, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, rhizoma atractylodis, chaulmoogra, the root of Dahurain angelica, kuh-seng, the root bark of white mulberry, soap
Frying 1~10 minute (length of time of different material component frying is different) are added in angle thorn, dandelion, rheum officinale one by one respectively, to
It is filtered while hot after being deep-fried；
(5) cool to above-mentioned weighed peppermint oil, Moschus, cow-bezoar is added after room temperature and stirs evenly；
(6) it is placed in sterile chamber, at paste after natural cooling.
In some embodiments of the above method of the present invention, the parts by weight of the sesame oil are 300 parts, and sesame oil
It is 3:1 with the weight fraction ratio of beeswax or vaseline.
In some embodiments of the present invention, above-mentioned cream drug can be filled to lipstick shape packaging after sterilizing
In container, to apply the paste medicine of the treatment acne using the usage mode of similar lipstick.
Beneficial effect
The present invention treats the paste of acne, has effects that clearing heat and detoxicating, eliminating toxic is outgoing, eliminating toxic dampness and heat, can effectively resist
Inflammation, antibacterial, moisturizing and skin care, it is effective in cure to the acne of different constitution crowds, each period different pathogeny, and nontoxic secondary work
With.The technique of use production paste of the present invention prepares the drug, and is innovatively filled in lipstick shape packing container,
So that product it is beautiful and generous, convenient for carrying, it is easy to use, can be applied directly to affected part, when smearing will not make dirty finger and
Other skin parts.With board a plane, high-speed rail when, the regulation that safety check carries liquid will not be limited by.
Specific embodiment
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..Unless otherwise specified, embodiment
Used in the conventional means that are well known to those skilled in the art of technological means.
Embodiment 1: the raw material components formula of the Chinese medicine composition of acne is treated
A kind of Chinese medicine composition for treating acne, active constituent are prepared (such as by the raw material components of following parts by weight
Every part be 1g when): Asian puccoon 3g, Fructus Forsythiae 3g, Radix Salviae Miltiorrhizae 1g, Cortex Phellodendri 1g, rhizoma atractylodis 3g, chaulmoogra 1g, root of Dahurain angelica 1g, kuh-seng 2g, the root bark of white mulberry
1g, spina gleditsiae 1g, dandelion 1g, rheum officinale 1g, peppermint oil 3g, Moschus 0.1g, cow-bezoar 0.1g.
Embodiment 2: the raw material components formula of the Chinese medicine composition of acne is treated
A kind of Chinese medicine composition for treating acne, active constituent are prepared (such as by the raw material components of following parts by weight
Every part be 1g when): Asian puccoon 6g, Fructus Forsythiae 2g, Radix Salviae Miltiorrhizae 2g, Cortex Phellodendri 5g, rhizoma atractylodis 1g, chaulmoogra 5g, root of Dahurain angelica 3g, kuh-seng 3g, the root bark of white mulberry
3g, spina gleditsiae 8g, dandelion 5g, rheum officinale 2g, peppermint oil 5g, Moschus 0.3g, cow-bezoar 0.2g.
Embodiment 3: the raw material components formula of the Chinese medicine composition of acne is treated
A kind of Chinese medicine composition for treating acne, active constituent are prepared (such as by the raw material components of following parts by weight
Every part be 1g when): Asian puccoon 10g, Fructus Forsythiae 15g, Radix Salviae Miltiorrhizae 3g, Cortex Phellodendri 10g, rhizoma atractylodis 8g, chaulmoogra 12g, root of Dahurain angelica 8g, kuh-seng 10g, mulberry
White skin 10g, spina gleditsiae 8g, dandelion 10g, rheum officinale 3g, peppermint oil 8g, Moschus 0.5g, cow-bezoar 0.4g.
Embodiment 4: the raw material components formula of the Chinese medicine composition of acne is treated
A kind of Chinese medicine composition for treating acne, active constituent are prepared (such as by the raw material components of following parts by weight
Every part be 1g when): Asian puccoon 10g, Fructus Forsythiae 5g, Radix Salviae Miltiorrhizae 4g, Cortex Phellodendri 8g, rhizoma atractylodis 5g, chaulmoogra 10g, root of Dahurain angelica 10g, kuh-seng 5g, Sang Bai
Skin 8g, spina gleditsiae 8g, dandelion 8g, rheum officinale 4g, peppermint oil 8g, Moschus 0.8g, cow-bezoar 0.3g.
Embodiment 5: the raw material components formula of the Chinese medicine composition of acne is treated
A kind of Chinese medicine composition for treating acne, active constituent are prepared (such as by the raw material components of following parts by weight
Every part be 1g when): Asian puccoon 15g, Fructus Forsythiae 10g, Radix Salviae Miltiorrhizae 5g, Cortex Phellodendri 3g, rhizoma atractylodis 10g, chaulmoogra 15g, root of Dahurain angelica 10g, kuh-seng 8g, mulberry
White skin 5g, spina gleditsiae 10g, dandelion 3g, rheum officinale 5g, peppermint oil 5g, Moschus 0.6g, cow-bezoar 0.5g.
Embodiment 6: the raw material components formula of the Chinese medicine composition of acne is treated
A kind of Chinese medicine composition for treating acne, active constituent are prepared (such as by the raw material components of following parts by weight
Every part be 1g when): Asian puccoon 8g, Fructus Forsythiae 8g, Radix Salviae Miltiorrhizae 3g, Cortex Phellodendri 5g, rhizoma atractylodis 5g, chaulmoogra 8g, root of Dahurain angelica 5g, kuh-seng 6g, the root bark of white mulberry
5g, spina gleditsiae 10g, dandelion 10g, rheum officinale 3g, peppermint oil 10g, Moschus 0.4g, cow-bezoar 0.3g.
A kind of embodiment 7: preparation method of the paste of easy-to-use treatment acne
(1) the composition of raw materials component of any one Chinese medicine composition of the Examples 1 to 6 of corresponding parts by weight is weighed, such as
Every part be 1g when；
(2) 80~1000g, preferably 300g sesame oil (preferably white sesameseed oil, i.e. ground sesameseed oil) be heated to 130 DEG C~
140℃；
(3) beeswax or vaseline are added into the sesame oil of step (2) and makes it dissolve, wherein sesame oil and beeswax or all
The weight fraction ratio of intellectual circle is 2.5~4:1, preferably 3:1；
(4) by above-mentioned weighed Asian puccoon, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, rhizoma atractylodis, chaulmoogra, the root of Dahurain angelica, kuh-seng, the root bark of white mulberry, soap
Frying 1~10 minute (length of time of different material component frying is different) are added in angle thorn, dandelion, rheum officinale one by one respectively, to
It is filtered while hot after being deep-fried；
(5) cool to above-mentioned weighed peppermint oil, Moschus, cow-bezoar is added after room temperature and stirs evenly；
(6) it is placed in sterile chamber, at paste after natural cooling.
Above-mentioned cream drug can be filled to after sterilizing in lipstick shape packing container, so as to using similar lipstick
Usage mode applies the paste medicine of the treatment acne.
Embodiment 8: the clinical application test of paste of the present invention
The following are according to embodiments of the present invention 1~6 it is described treatment acne Chinese medicine composition raw material components formula, according to
The clinical trial of the paste medicine of the treatment acne of 7 the method for embodiment preparation
Select in August, 2010 to patients with acne 150 during in July, 2017, wherein male 68, women 82, year
Age 15~40 years old, average age about 23 years old.Case is included in standard: one or more are more for forehead, cheekbone portion, cheek, mouth week, back etc.
Rubescent color acne or the fusion of part acne are in blocks；Occasionally there are bleeding, furfur or top at white pus point；Pink tongue or red, tongue fur are thin
Yellow or yellow greasy, slippery；Cover in case from slightly to serious different degrees of acne conditions.
Patient is divided into 6 groups, every group of 25 people, institute prepared by the raw material components formula of above embodiments 1~6 is pressed in application respectively
It states paste to be treated, within 30 days treatment times by a definite date, external application daily morning and evening is shown in based on different degrees of patients with acne
Acne is relieved that such as acne significantly reduces or pus point collapses in fast one week of effect；The shrivelled non-goodbye furfur of acne after 10 days,
Acne disappears without new hair acne after 15 days；Acne disappears substantially after 30 days in general.
6 kinds of paste prepared by embodiment 7 are applied to above-mentioned 6 groups of patients respectively, and treatment starts at the end of and ties
Follow-up results are as shown in the table (in 12 months) after beam:
It can be seen that by result above, the paste that the present invention treats acne has good curative effect, wherein embodiment 2,3,4,6
Raw material components formula preparation paste curative effect be substantially better than embodiment 1 and 5 raw material components formula preparation paste, and its
The paste curative effect of the raw material components formula preparation of middle embodiment 3 is best.
Although above the present invention is described in detail with a general description of the specific embodiments,
On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause
This, these modifications or improvements, fall within the scope of the claimed invention without departing from theon the basis of the spirit of the present invention.
Claims (10)
1. a kind of Chinese medicine composition for treating acne, which is characterized in that the active constituent of the Chinese medicine composition is by following weight
The raw material components of part are prepared: 3~15 parts of Asian puccoon, 2~15 parts of Fructus Forsythiae, 1~5 part of Radix Salviae Miltiorrhizae, 1~10 part of Cortex Phellodendri, rhizoma atractylodis 1~10
Part, 1~15 part of chaulmoogra, 1~10 part of the root of Dahurain angelica, 2~10 parts of kuh-seng, 1~10 part of the root bark of white mulberry, 1~10 part of spina gleditsiae, dandelion 1
~10 parts, 1~5 part of rheum officinale, 3~10 parts of peppermint oil, 0.1~0.8 part of Moschus, 0.1~0.5 part of cow-bezoar.
2. Chinese medicine composition as described in claim 1, which is characterized in that the active constituent of the Chinese medicine composition is by following heavy
The raw material components of amount part are prepared: 8~15 parts of Asian puccoon, 10~15 parts of Fructus Forsythiae, 2~4 parts of Radix Salviae Miltiorrhizae, 8~10 parts of Cortex Phellodendri, rhizoma atractylodis 8
~10 parts, 8~12 parts of chaulmoogra, 8~10 parts of the root of Dahurain angelica, 5~8 parts of kuh-seng, 8~10 parts of the root bark of white mulberry, 8~10 parts of spina gleditsiae, Pu Gong
3~10 parts of English, 2~4 parts of rheum officinale, 5~8 parts of peppermint oil, 0.3~0.6 part of Moschus, 0.2~0.4 part of cow-bezoar.
3. Chinese medicine composition as claimed in claim 2, which is characterized in that the active constituent of the Chinese medicine composition is by following heavy
Amount part raw material components be prepared: 10 parts of Asian puccoon, 15 parts of Fructus Forsythiae, 3 parts of Radix Salviae Miltiorrhizae, 10 parts of Cortex Phellodendri, 8 parts of rhizoma atractylodis, 12 parts of chaulmoogra,
8 parts of the root of Dahurain angelica, 10 parts of kuh-seng, 10 parts of the root bark of white mulberry, 8 parts of spina gleditsiae, 10 parts of dandelion, 3 parts of rheum officinale, 8 parts of peppermint oil, 0.5 part of Moschus,
0.4 part of cow-bezoar.
4. application of the Chinese medicine composition described in any one of claim 1-3 in the relevant product of preparation treatment acne, described
Product includes drug, health care product, cosmetics.
5. a kind of paste for treating acne, which is characterized in that the paste is by Chinese medicine group of any of claims 1-3
Object, sesame oil and beeswax or vaseline composition are closed, wherein the parts by weight of the sesame oil are 80~1000 parts, and sesame oil
It is 2.5~4:1 with the weight fraction ratio of beeswax or vaseline.
6. paste as claimed in claim 5, which is characterized in that wherein the parts by weight of the sesame oil are 300 parts, and sesame
Oil is 3:1 with the weight fraction ratio of beeswax or vaseline.
7. such as paste described in claim 5 or 6, which is characterized in that the paste is lipstick shape paste, and method of application is similar to
The smearing of lipstick.
8. a kind of preparation method for the paste for treating acne, which is characterized in that comprise the following steps:
(1) raw material components of Chinese medicine composition described in any one of claim 1-3 of corresponding parts by weight are weighed；
(2) sesame oil is heated to 130 DEG C~140 DEG C, wherein the parts by weight of the sesame oil are 80~1000 parts；
(3) beeswax or vaseline are added into the sesame oil of step (2) and makes it dissolve, wherein the sesame oil and beeswax or all
The weight fraction ratio of intellectual circle is 2.5~4:1；
(4) by above-mentioned weighed Asian puccoon, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, rhizoma atractylodis, chaulmoogra, the root of Dahurain angelica, kuh-seng, the root bark of white mulberry, spina gleditsiae,
Frying 1~10 minute is added in dandelion, rheum officinale one by one respectively, filters while hot after being deep-fried；
(5) cool to above-mentioned weighed peppermint oil, Moschus, cow-bezoar is added after room temperature and stirs evenly；
(6) it is placed in sterile chamber, at paste after natural cooling.
9. method according to claim 8, which is characterized in that wherein the parts by weight of the sesame oil are 300 parts, and sesame
Oil is 3:1 with the weight fraction ratio of beeswax or vaseline.
10. a kind of product for treating acne, which is characterized in that paste described in claim 5-9 is filled to lipstick shape packet
In packaging container, to apply the paste medicine of the treatment acne using the usage mode of similar lipstick.
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