CN109846849A - A kind of masticable nutritional supplement soft capsule and preparation method thereof - Google Patents
A kind of masticable nutritional supplement soft capsule and preparation method thereof Download PDFInfo
- Publication number
- CN109846849A CN109846849A CN201910179459.5A CN201910179459A CN109846849A CN 109846849 A CN109846849 A CN 109846849A CN 201910179459 A CN201910179459 A CN 201910179459A CN 109846849 A CN109846849 A CN 109846849A
- Authority
- CN
- China
- Prior art keywords
- parts
- powder
- soft capsule
- capsule
- glue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007901 soft capsule Substances 0.000 title claims abstract description 123
- 235000015872 dietary supplement Nutrition 0.000 title claims abstract description 50
- 238000002360 preparation method Methods 0.000 title claims abstract description 42
- 239000000843 powder Substances 0.000 claims abstract description 256
- 239000002775 capsule Substances 0.000 claims abstract description 124
- 235000001674 Agaricus brunnescens Nutrition 0.000 claims abstract description 94
- 235000009337 Spinacia oleracea Nutrition 0.000 claims abstract description 85
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 54
- 235000012054 meals Nutrition 0.000 claims abstract description 49
- 229920002472 Starch Polymers 0.000 claims abstract description 41
- 239000008107 starch Substances 0.000 claims abstract description 41
- 235000019698 starch Nutrition 0.000 claims abstract description 41
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 36
- 239000011707 mineral Substances 0.000 claims abstract description 36
- 235000013336 milk Nutrition 0.000 claims abstract description 35
- 239000008267 milk Substances 0.000 claims abstract description 35
- 210000004080 milk Anatomy 0.000 claims abstract description 35
- 240000006053 Garcinia mangostana Species 0.000 claims abstract description 34
- 235000017048 Garcinia mangostana Nutrition 0.000 claims abstract description 34
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 34
- 239000008103 glucose Substances 0.000 claims abstract description 34
- 150000003839 salts Chemical class 0.000 claims abstract description 34
- GUBGYTABKSRVRQ-QKKXKWKRSA-N lactose group Chemical group OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims abstract description 33
- 239000000832 lactitol Substances 0.000 claims abstract description 32
- 235000010448 lactitol Nutrition 0.000 claims abstract description 32
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 claims abstract description 32
- 229960003451 lactitol Drugs 0.000 claims abstract description 32
- 239000008101 lactose Substances 0.000 claims abstract description 32
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 claims abstract description 31
- 239000004006 olive oil Substances 0.000 claims abstract description 31
- 235000008390 olive oil Nutrition 0.000 claims abstract description 31
- 239000002994 raw material Substances 0.000 claims abstract description 29
- 235000013312 flour Nutrition 0.000 claims abstract description 24
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims abstract description 21
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims abstract description 21
- 239000008108 microcrystalline cellulose Substances 0.000 claims abstract description 21
- 229940016286 microcrystalline cellulose Drugs 0.000 claims abstract description 21
- 239000003349 gelling agent Substances 0.000 claims abstract description 16
- 238000004519 manufacturing process Methods 0.000 claims abstract description 16
- 239000004014 plasticizer Substances 0.000 claims abstract description 6
- 239000006071 cream Substances 0.000 claims abstract description 4
- 239000003292 glue Substances 0.000 claims description 116
- 241000219315 Spinacia Species 0.000 claims description 84
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 81
- 241001474374 Blennius Species 0.000 claims description 40
- 238000003756 stirring Methods 0.000 claims description 38
- 239000011265 semifinished product Substances 0.000 claims description 25
- 238000010438 heat treatment Methods 0.000 claims description 24
- 239000004615 ingredient Substances 0.000 claims description 17
- 238000010792 warming Methods 0.000 claims description 14
- 230000036760 body temperature Effects 0.000 claims description 12
- 238000001816 cooling Methods 0.000 claims description 12
- 230000018044 dehydration Effects 0.000 claims description 12
- 238000006297 dehydration reaction Methods 0.000 claims description 12
- 238000011049 filling Methods 0.000 claims description 12
- 230000035876 healing Effects 0.000 claims description 12
- 238000011068 loading method Methods 0.000 claims description 12
- 238000005303 weighing Methods 0.000 claims description 12
- 235000013339 cereals Nutrition 0.000 claims description 11
- 235000016709 nutrition Nutrition 0.000 claims description 11
- 239000011257 shell material Substances 0.000 claims description 11
- 230000035764 nutrition Effects 0.000 claims description 10
- 239000000047 product Substances 0.000 claims description 10
- 239000007787 solid Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 7
- 239000003795 chemical substances by application Substances 0.000 claims description 4
- 240000007817 Olea europaea Species 0.000 claims description 2
- 238000000748 compression moulding Methods 0.000 claims description 2
- 238000004321 preservation Methods 0.000 claims description 2
- 238000002791 soaking Methods 0.000 claims description 2
- 239000008273 gelatin Substances 0.000 abstract description 17
- 229920000159 gelatin Polymers 0.000 abstract description 17
- 108010010803 Gelatin Proteins 0.000 abstract description 15
- 235000019322 gelatine Nutrition 0.000 abstract description 15
- 235000011852 gelatine desserts Nutrition 0.000 abstract description 15
- 235000013305 food Nutrition 0.000 abstract description 5
- 230000001934 delay Effects 0.000 abstract description 3
- 230000036541 health Effects 0.000 abstract description 3
- 244000300264 Spinacia oleracea Species 0.000 abstract 1
- 235000010755 mineral Nutrition 0.000 description 31
- 239000000499 gel Substances 0.000 description 14
- 235000010980 cellulose Nutrition 0.000 description 12
- 229920002678 cellulose Polymers 0.000 description 12
- 239000001913 cellulose Substances 0.000 description 12
- 238000004108 freeze drying Methods 0.000 description 9
- 239000000463 material Substances 0.000 description 8
- 241000196324 Embryophyta Species 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 7
- 241001465754 Metazoa Species 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 230000002195 synergetic effect Effects 0.000 description 5
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 239000011575 calcium Substances 0.000 description 4
- 229910052791 calcium Inorganic materials 0.000 description 4
- 235000001465 calcium Nutrition 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 235000018102 proteins Nutrition 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 229920002261 Corn starch Polymers 0.000 description 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 description 3
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 235000001014 amino acid Nutrition 0.000 description 3
- 150000001413 amino acids Chemical class 0.000 description 3
- 238000009835 boiling Methods 0.000 description 3
- 238000010411 cooking Methods 0.000 description 3
- 239000008120 corn starch Substances 0.000 description 3
- 238000004132 cross linking Methods 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 239000011591 potassium Substances 0.000 description 3
- 229910052700 potassium Inorganic materials 0.000 description 3
- 235000007686 potassium Nutrition 0.000 description 3
- 239000000523 sample Substances 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 239000013589 supplement Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- 241000195493 Cryptophyta Species 0.000 description 2
- 241000167880 Hirundinidae Species 0.000 description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 2
- 206010036790 Productive cough Diseases 0.000 description 2
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 230000029087 digestion Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 235000012907 honey Nutrition 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 239000006101 laboratory sample Substances 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 210000003097 mucus Anatomy 0.000 description 2
- 239000011574 phosphorus Substances 0.000 description 2
- 229910052698 phosphorus Inorganic materials 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 229910052711 selenium Inorganic materials 0.000 description 2
- 239000011669 selenium Substances 0.000 description 2
- 210000003802 sputum Anatomy 0.000 description 2
- 208000024794 sputum Diseases 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 1
- 102100033770 Alpha-amylase 1C Human genes 0.000 description 1
- 240000001592 Amaranthus caudatus Species 0.000 description 1
- 235000009328 Amaranthus caudatus Nutrition 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- SGHZXLIDFTYFHQ-UHFFFAOYSA-L Brilliant Blue Chemical compound [Na+].[Na+].C=1C=C(C(=C2C=CC(C=C2)=[N+](CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C=2C(=CC=CC=2)S([O-])(=O)=O)C=CC=1N(CC)CC1=CC=CC(S([O-])(=O)=O)=C1 SGHZXLIDFTYFHQ-UHFFFAOYSA-L 0.000 description 1
- 241000206575 Chondrus crispus Species 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000131522 Citrus pyriformis Species 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000001188 FEMA 4487 Substances 0.000 description 1
- 208000005016 Intestinal Neoplasms Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 108010026386 Salivary alpha-Amylases Proteins 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 239000004376 Sucralose Substances 0.000 description 1
- 210000001744 T-lymphocyte Anatomy 0.000 description 1
- 244000185386 Thladiantha grosvenorii Species 0.000 description 1
- 235000011171 Thladiantha grosvenorii Nutrition 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 229930003451 Vitamin B1 Natural products 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229930003448 Vitamin K Natural products 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000001785 acacia senegal l. willd gum Substances 0.000 description 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 235000012735 amaranth Nutrition 0.000 description 1
- 239000004178 amaranth Substances 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000036592 analgesia Effects 0.000 description 1
- 229910052785 arsenic Inorganic materials 0.000 description 1
- RQNWIZPPADIBDY-UHFFFAOYSA-N arsenic atom Chemical compound [As] RQNWIZPPADIBDY-UHFFFAOYSA-N 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000002567 autonomic effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001055 chewing effect Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000013325 dietary fiber Nutrition 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000006694 eating habits Nutrition 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 239000007903 gelatin capsule Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 201000002313 intestinal cancer Diseases 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 201000002364 leukopenia Diseases 0.000 description 1
- 231100001022 leukopenia Toxicity 0.000 description 1
- 230000004301 light adaptation Effects 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 235000019659 mouth feeling Nutrition 0.000 description 1
- 235000006408 oxalic acid Nutrition 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 210000003800 pharynx Anatomy 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 229940085605 saccharin sodium Drugs 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 235000019408 sucralose Nutrition 0.000 description 1
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 238000010301 surface-oxidation reaction Methods 0.000 description 1
- 229960003495 thiamine Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 239000005418 vegetable material Substances 0.000 description 1
- 235000003563 vegetarian diet Nutrition 0.000 description 1
- 235000010374 vitamin B1 Nutrition 0.000 description 1
- 239000011691 vitamin B1 Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 239000011712 vitamin K Substances 0.000 description 1
- 235000019168 vitamin K Nutrition 0.000 description 1
- 150000003721 vitamin K derivatives Chemical class 0.000 description 1
- 229940046010 vitamin k Drugs 0.000 description 1
- 230000010148 water-pollination Effects 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 206010048282 zoonosis Diseases 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to a kind of masticable nutritional supplement soft capsules and preparation method thereof, it solves the prior art gelatin soft capsule solution rate is slow in water, be also easy to produce to unite and delay solution rate, disintegration delays phenomenon obvious, production efficiency is low, and security risk is big, the technical problem of external form ball easy to stick, chewable property difference.The present invention provides a kind of masticable nutritional supplement soft capsule, according to parts by weight, capsule shells inner stuffing raw material include following components: 10-20 part of seawood meal, 1-10 part of mushroom powder, 1-2 parts of spinach powder, cream 1-10 parts of mineral salt, 1-2 parts of malt flour, 1-2 parts of milk powder, 2-6 parts of lactitol, 0.1-6 parts of mangosteen powder, remaining be olive oil 40-82.9 parts；Capsule shells raw material include gelling agent and plasticizer, and gelling agent is hydroxypropul starch, and plasticizer is lactose, microcrystalline cellulose, glucose any of which or several；Preparation method is also provided simultaneously.The present invention is widely used in field of health care food.
Description
Technical field
The invention belongs to field of health care food, and in particular to a kind of masticable nutritional supplement soft capsule and its system
Preparation Method.
Background technique
Soft capsule is to be sealed in liquid charging stock or juicy fruit body mixture in soft capsule material and a kind of manufactured glue through processing
Wafer.Capsule is widely used, and is one of widest dosage form of the industrial applications such as medicine, health care product.Soft capsule shell be with gelatin,
Glycerol or other suitable pharmaceutic adjuvants individually or are mixed, and have the characteristics that covering peculiar smell, domestic soft capsule is mainly with bright
Glue is that raw material is produced, and gelatin is a kind of excellent thermoreversible gels agent, but the usually presence of the soft capsule of gelatin preparation is collapsed
Solution delays phenomenon obvious, and analysis reason is that the substances such as low molecule aldehydes and gelatin oxidation process can make amino acid in gelatin
The aging that crosslinking causes gelatin is generated between side-chain radical, the phenomenon that changing the dissolution properties of capsule shells, disintegration is caused to delay.
Gelatin is mainly made of raw materials such as Animal Bone, skins, belongs to animal derived capsule.On the one hand for Islamic or vegetarian diet master
For justice, the application of animal source capsule is limited, and gelatin product does not indicate its animal origin, therefore does not meet certain religious belief people
And vegetarian eating habit, limit the use of gelatin.On the other hand, the supervision of food auxiliary material also tends to be stringent, at
Originally it gradually rises, the zoonosis such as rabid ox disease, aftosa take place frequently, and gelatin soft capsule easily causes animal sources infectious disease, bright
There is security risk in glue, these all promote people to study autonomic soft capsules to substitute traditional gelatin glue to a certain extent
Capsule, and existing soft capsule softgel shell uses xanthan gum, carragheen and Arabic gum etc. more, these natural plant gum dissolve speed in water
Degree is slow, is also easy to produce to unite and delays solution rate, and production efficiency is low, is unfavorable for the practical operation of mass production.These make soft-gelatin
The production and sales of capsule are very limited.Therefore before replacing gelatin that there is good market using safe and healthy vegetable material
Scape.
Plant capsule becomes development trend, and the annual growth of plant capsule is 25 parts in the world at present.It is soft with traditional gelatin
Capsule is compared, and the thermal stability of soft capsule is more outstanding, even more than 50 DEG C of environment, can also remain complete outer
Type, it is indeformable, ball is not glued, the requirement to summer transport and storage is reduced and transparency is higher.
Summary of the invention
The object of the invention is in order to overcome the above-mentioned deficiencies of the prior art, provide a kind of nutrition of raw material composition comprehensively,
Ratio science, disintegration rate are fast, are easily absorbed by the body, securely and reliably, stable in physicochemical property, external form high to temperature and humidity stability
Not viscous ball, good toughness and the high grade of transparency, masticable nutritional supplement soft capsule of free from extraneous odour and preparation method thereof.
The technical proposal for solving the technical problem of the invention is:
A kind of masticable nutritional supplement soft capsule, according to parts by weight, capsule shells inner stuffing raw material includes
Following components: 10-20 parts of seawood meal, 1-10 parts of mushroom powder, 1-2 parts of spinach powder, newborn 1-10 parts of mineral salt, 1-2 parts of malt flour, cream
1-2 parts of powder, 2-6 parts of lactitol, 0.1-6 parts of mangosteen powder, remaining be olive oil 40-82.9 parts；Capsule shells raw material include glue
Solidifying agent and plasticizer, gelling agent are hydroxypropul starch, plasticizer be lactose, microcrystalline cellulose, glucose any of which or
It is several.
Preferably, seawood meal, mushroom powder and spinach powder are respectively seaweed super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach
Super-micro wall-broken powder, and be new fresh seaweed, mushroom and the spinach for being picked up choosing, it first arranges, clean respectively, after water blancing curing,
Using under vacuum condition freeze-drying again at water content is to be crushed to and be averaged using micronizer after 5% dehydration below is dry
Partial size is to 2 microns hereinafter, obtained seaweed super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder.
Preferably, according to parts by weight, capsule shells inner stuffing raw material includes following components: 12-18 parts of seawood meal, mushroom
3-8 parts of powder, 1.5 parts of spinach powder, newborn 3-8 parts of mineral salt, 1-2 parts of malt flour, 1-2 parts of milk powder, 2-6 parts of lactitol, mangosteen powder
0.1-6 parts, remaining be olive oil 60-82.9 parts.
Preferably, according to parts by weight, capsule shell material includes 40-80 parts of hydroxypropul starch, 10-40 parts of lactose, crystallite
1-20 parts of cellulose, 1-10 parts of glucose, remaining be water 100-120 parts and 10-30 parts of glycerol.
Preferably, capsule shells are with a thickness of 0.35~1.00mm.
A kind of production method of masticable nutritional supplement soft capsule of above-mentioned any one, including following step
It is rapid:
Step 1: ingredient and weighing: number weighs according to the required weight: seawood meal, mushroom powder, spinach powder, newborn mineral salt, wheat
Bud powder, milk powder, lactitol, mangosteen powder, olive oil；Number weighs capsule shells raw material: hydroxypropul starch, cream according to the required weight
Sugar, microcrystalline cellulose, glucose, remaining be water and glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, mushroom powder, spinach powder, newborn mineral
Salt, malt flour, milk powder, lactitol, mangosteen powder, olive oil are uniformly mixed, and capsule shells inner stuffing is made；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 35-45 DEG C, then hydroxypropul starch is added in glue pot, lactose, micro- is then added while stirring
It after crystalline cellulose, glucose addition completely, is further continued for heating and collosol temperature is raised between 95-105 DEG C, stop heating, heat preservation
Afterwards, stirring is closed, deaeration obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 60~95 DEG C of glue box, so
Soft capsule host is opened afterwards, so that glue is flowed out to 15~25 DEG C of temperature of cooling drum from glue box, rubber is made, rubber thickness exists
0.35~1.00mm, while capsule shells inner stuffing made from step 2 being added into the hopper of encapsulating machine, adjust sprinkler body temperature
35~70 DEG C of degree makes capsule crack healing thickness meet the requirements, and can be suppressed after adjustment filling loading amount, plant flexible glue is made
Capsule semi-finished product；
Step 5: obtaining the masticable battalion of the present invention after soft capsule semi-finished product made from step 4 are dried
Support replenishers soft capsule.
Preferably, in step 2, the form for being uniformly mixed to capsule shells inner stuffing is solid gel.
Preferably, in step 3, after being first warming up to 40 DEG C, then will be in hydroxypropul starch addition glue pot.
Preferably, in step 3, soaking time is after twenty minutes, to close stirring, deaeration step are as follows: it vacuumizes 3 minutes, until
Air pressure is -0.02MPa, keeps the temperature standing and defoaming 4-5 hours.
It preferably, further include Step 5: dry: the soft capsule semi-finished product of step 4 compression moulding are dry to rubber
Moisture 7~15%.
Beneficial effects of the present invention:
(1) masticable nutritional supplement soft capsule prepared by the present invention, nutrition is comprehensive, ratio is scientific, function because
The bioavailability of son is high, and stable in physicochemical property, securely and reliably, and materials are simple, and efficacy exertion ability is strong compared with common product,
It is significant in efficacy, it is easily absorbed by the body, absorption rate is high；Production cost is low, and production method is continuously uninterrupted, greatly improves production
Efficiency has great economic benefit.
(2) the masticable nutritional supplement soft capsule of the method for the present invention preparation, to temperature and humidity stability height, toughness
The good and high grade of transparency.This product uses hydroxypropul starch for softgel shell raw material, with lactose, microcrystalline cellulose, edible glucose etc. help with
Auxiliary material forms softgel shell, and with natural nutrient replenishers raw material, assistant forms content with auxiliary material, avoids anti-with content generation crosslinking
Answer, enhance sensitive to temperature and humidity, stability improves, and chewiness is preferable, can cover bad smell, the high grade of transparency, and to it is damp and hot compared with
Stable soft capsule product.(3) seawood meal, mushroom powder or mushroom oil, spinach powder, newborn mineral salt, malt flour, milk powder, olive
As capsule 's content, lactose, microcrystalline cellulose, glucose make capsule more as rubber powder ingredient for olive oil, lactitol, mangosteen powder
Q bullet；Lactose, microcrystalline cellulose, glucose, which are added to, on the basis of original natural plant gum (hydroxypropul starch) significantly increases capsule nozzle
Chewing property hides bad smell.
Seawood meal, mushroom powder, spinach powder, milk powder and mangosteen powder synergistic effect, cover respective bad smell, simultaneously
The form of capsule shells inner stuffing is set to become solid gel shape, it is further synergistic with capsule shells, it is chewable to improve the present invention
Nutritional supplement soft capsule appearance good toughness, transparency is high, no bad smell, and Q bullet sense significantly improves in mouthfeel, full
The mouthfeel demand of sufficient people.
(4) the masticable nutritional supplement soft capsule of the method for the present invention preparation, seawood meal, newborn mineral salt add together
Adding makes capsule have effects that high calcium.
Specific embodiment
The present invention is further explained in the light of specific embodiments, to help the contents of the present invention are understood.The present invention
Used in method unless otherwise required, be conventional production method；Used raw material is unless otherwise required
Conventional commercial product.
Embodiment 1
Prepare a kind of masticable nutritional supplement soft capsule, comprising the following steps:
Step 1: ingredient and weighing:
Number weighs according to the required weight: 10 parts of seawood meal, 1 part of mushroom powder, 1 part of spinach powder, newborn 1 part of mineral salt, malt flour 1
Part, 1 part of milk powder, 2 parts of lactitol, 0.1 part of mangosteen powder, 82.9 parts of olive oil, seawood meal, mushroom powder and spinach powder are respectively sea
Algae super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder, and be new fresh seaweed, mushroom and the spinach for being picked up choosing
Dish is first arranged respectively, is cleaned, after water blancing curing, then using freeze-drying under vacuum condition below for 5% at water content
After dehydration is dry, average grain diameter is crushed to 2 microns using micronizer hereinafter, obtained seaweed super-micro wall-broken powder, mushroom are super
Micro- wall cell disruption powder and spinach super-micro wall-broken powder；
Number weighs capsule shells raw material: 40 parts of gelling agent hydroxypropul starch, 10 parts of lactose, microcrystalline cellulose according to the required weight
Element 1 part, 1 part of glucose, remaining be 120 parts of water and 30 parts of glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, mushroom powder, spinach powder, newborn mineral
The form that salt, malt flour, milk powder, lactitol, mangosteen powder, olive oil are uniformly mixed to capsule shells inner stuffing is solid-state
Capsule shells inner stuffing is made in gel；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 35 DEG C, then by hydroxypropul starch addition glue pot, lactose, crystallite are then added while stirring
After cellulose, glucose addition completely, it is further continued for heating and collosol temperature is raised between 95 DEG C, stop heating, keep the temperature 20 minutes
Afterwards, stirring is closed, deaeration: vacuumizing 3 minutes, until air pressure is -0.02MPa, keeps the temperature standing and defoaming 4 hours, obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 60 DEG C of glue box, is then opened
Soft capsule host is opened, so that glue is flowed out to 15~25 DEG C of temperature of cooling drum from glue box, rubber is made, rubber thickness exists
0.35mm, while capsule shells inner stuffing made from step 2 being added into the hopper of encapsulating machine, adjust 35 DEG C of sprinkler body temperature
So that capsule crack healing thickness is met the requirements, can be suppressed after adjustment filling loading amount, soft capsule semi-finished product are made；
Step 5: being dried soft capsule semi-finished product made from step 4 to rubber moisture 7%, this hair is obtained
Bright masticable nutritional supplement soft capsule.
Embodiment 2
Prepare a kind of masticable nutritional supplement soft capsule, comprising the following steps:
Step 1: ingredient and weighing:
Number weighs according to the required weight: 20 parts of seawood meal, 10 parts of mushroom powder, 2 parts of spinach powder, newborn 10 parts of mineral salt, malt
2 parts of powder, 2 parts of milk powder, 6 parts of lactitol, 6 parts of mangosteen powder, 40 parts of olive oil, seawood meal, mushroom powder and spinach powder are respectively sea
Algae super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder, and be new fresh seaweed, mushroom and the spinach for being picked up choosing
Dish is first arranged respectively, is cleaned, after water blancing curing, then using freeze-drying under vacuum condition below for 5% at water content
After dehydration is dry, average grain diameter is crushed to 2 microns using micronizer hereinafter, obtained seaweed super-micro wall-broken powder, mushroom are super
Micro- wall cell disruption powder and spinach super-micro wall-broken powder；
Number weighs capsule shells raw material: 80 parts of gelling agent hydroxypropul starch, 40 parts of lactose, microcrystalline cellulose according to the required weight
Element 20 parts, 10 parts of glucose, remaining be 100 parts of water and 10 parts of glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, mushroom powder, spinach powder, newborn mineral
The form that salt, malt flour, milk powder, lactitol, mangosteen powder, olive oil are uniformly mixed to capsule shells inner stuffing is solid-state
Capsule shells inner stuffing is made in gel；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 45 DEG C, then by hydroxypropul starch addition glue pot, lactose, crystallite are then added while stirring
After cellulose, glucose addition completely, it is further continued for heating and collosol temperature is raised between 105 DEG C, stop heating, keep the temperature 20 minutes
Afterwards, stirring is closed, deaeration: vacuumizing 3 minutes, until air pressure is -0.02MPa, keeps the temperature standing and defoaming 5 hours, obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 95 DEG C of glue box, is then opened
Open soft capsule host, glue made to flow out to 25 DEG C of temperature of cooling drum from glue box, be made rubber, rubber thickness in 1.00mm,
Capsule shells inner stuffing made from step 2 is added into the hopper of encapsulating machine simultaneously, adjustment sprinkler body temperature 70 C makes capsule clamping
Seam healing thickness meets the requirements, and can be suppressed after adjustment filling loading amount, soft capsule semi-finished product are made；
Step 5: being dried soft capsule semi-finished product made from step 4 to rubber moisture 15%, this is obtained
Invent masticable nutritional supplement soft capsule.
Embodiment 3
Prepare a kind of masticable nutritional supplement soft capsule, comprising the following steps:
Step 1: ingredient and weighing:
Number weighs according to the required weight: 12 parts of seawood meal, 3 parts of mushroom powder, 1.5 parts of spinach powder, newborn 3 parts of mineral salt, malt
1 part of powder, 1 part of milk powder, 2 parts of lactitol, 0.1 part of mangosteen powder, remaining be 60 parts of olive oil, seawood meal, mushroom powder and spinach powder
Respectively seaweed super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder, and be the new fresh seaweed for being picked up choosing, mushroom
Mushroom and spinach first arrange respectively, clean, after water blancing curing, then use and be freeze-dried into water content under vacuum condition as 5%
After dehydration below is dry, average grain diameter is crushed to 2 microns using micronizer hereinafter, obtain seaweed super-micro wall-broken powder,
Mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder；
Number weighs capsule shells raw material: 45 parts of gelling agent hydroxypropul starch, 15 parts of lactose, microcrystalline cellulose according to the required weight
Element 5 parts, 8 parts of glucose, remaining be 110 parts of water and 20 parts of glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, mushroom powder, spinach powder, newborn mineral
The form that salt, malt flour, milk powder, lactitol, mangosteen powder, olive oil are uniformly mixed to capsule shells inner stuffing is solid-state
Capsule shells inner stuffing is made in gel；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 40 DEG C, then by hydroxypropul starch addition glue pot, lactose, crystallite are then added while stirring
After cellulose, glucose addition completely, it is further continued for heating and collosol temperature is raised between 100 DEG C, stop heating, keep the temperature 20 minutes
Afterwards, stirring is closed, deaeration: vacuumizing 3 minutes, until air pressure is -0.02MPa, keeps the temperature standing and defoaming 4 hours, obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 75 DEG C of glue box, is then opened
Open soft capsule host, glue made to flow out to 20 DEG C of temperature of cooling drum from glue box, be made rubber, rubber thickness in 0.65mm,
Capsule shells inner stuffing made from step 2 is added into the hopper of encapsulating machine simultaneously, adjustment sprinkler body temperature 45 C makes capsule clamping
Seam healing thickness meets the requirements, and can be suppressed after adjustment filling loading amount, soft capsule semi-finished product are made；
Step 5: being dried soft capsule semi-finished product made from step 4 to rubber moisture 8%, this hair is obtained
Bright masticable nutritional supplement soft capsule.
Embodiment 4
Prepare a kind of masticable nutritional supplement soft capsule, comprising the following steps:
Step 1: ingredient and weighing:
Number weighs according to the required weight: 18 parts of seawood meal, 8 parts of mushroom powder, 1.5 parts of spinach powder, newborn 8 parts of mineral salt, malt
2 parts of powder, 2 parts of milk powder, 6 parts of lactitol, 6 parts of mangosteen powder, remaining be 82.9 parts of olive oil, seawood meal, mushroom powder and spinach powder
Respectively seaweed super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder, and be the new fresh seaweed for being picked up choosing, mushroom
Mushroom and spinach first arrange respectively, clean, after water blancing curing, then use and be freeze-dried into water content under vacuum condition as 5%
After dehydration below is dry, average grain diameter is crushed to 2 microns using micronizer hereinafter, obtain seaweed super-micro wall-broken powder,
Mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder；
Number weighs capsule shells raw material: 70 parts of gelling agent hydroxypropul starch, 30 parts of lactose, microcrystalline cellulose according to the required weight
Element 15 parts, 8 parts of glucose, remaining be 110 parts of water and 20 parts of glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, mushroom powder, spinach powder, newborn mineral
The form that salt, malt flour, milk powder, lactitol, mangosteen powder, olive oil are uniformly mixed to capsule shells inner stuffing is solid-state
Capsule shells inner stuffing is made in gel；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 40 DEG C, then by hydroxypropul starch addition glue pot, lactose, crystallite are then added while stirring
After cellulose, glucose addition completely, it is further continued for heating and collosol temperature is raised between 100 DEG C, stop heating, keep the temperature 20 minutes
Afterwards, stirring is closed, deaeration: vacuumizing 3 minutes, until air pressure is -0.02MPa, keeps the temperature standing and defoaming 5 hours, obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 85 DEG C of glue box, is then opened
Open soft capsule host, glue made to flow out to 20 DEG C of temperature of cooling drum from glue box, be made rubber, rubber thickness in 0.85mm,
Capsule shells inner stuffing made from step 2 is added into the hopper of encapsulating machine simultaneously, 65 DEG C of sprinkler body temperature of adjustment makes capsule clamping
Seam healing thickness meets the requirements, and can be suppressed after adjustment filling loading amount, soft capsule semi-finished product are made；
Step 5: being dried soft capsule semi-finished product made from step 4 to rubber moisture 12%, this is obtained
Invent masticable nutritional supplement soft capsule.
Embodiment 5
Prepare a kind of masticable nutritional supplement soft capsule, comprising the following steps:
Step 1: ingredient and weighing:
Number weighs according to the required weight: 15 parts of seawood meal, 5.5 parts of mushroom powder, 1.5 parts of spinach powder, newborn 5.5 parts of mineral salt,
1.5 parts of malt flour, 1.5 parts of milk powder, 4 parts of lactitol, 3.5 parts of mangosteen powder, remaining be 78 parts of olive oil, seawood meal, mushroom powder
It is respectively seaweed super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder with spinach powder, and is picked up choosing new
Fresh seaweed, mushroom and spinach first arrange, clean, respectively after water blancing curing, then using freeze-drying under vacuum condition at containing
Water is to be crushed to average grain diameter to 2 microns using micronizer hereinafter, obtained seaweed is super after 5% dehydration below is dry
Micro- wall cell disruption powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder；
Number weighs capsule shells raw material: 60 parts of gelling agent hydroxypropul starch, 25 parts of lactose, microcrystalline cellulose according to the required weight
Element 11 parts, 6 parts of glucose, remaining be 110 parts of water and 20 parts of glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, mushroom powder, spinach powder, newborn mineral
The form that salt, malt flour, milk powder, lactitol, mangosteen powder, olive oil are uniformly mixed to capsule shells inner stuffing is solid-state
Capsule shells inner stuffing is made in gel；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 40 DEG C, then by hydroxypropul starch addition glue pot, lactose, crystallite are then added while stirring
After cellulose, glucose addition completely, it is further continued for heating and collosol temperature is raised between 100 DEG C, stop heating, keep the temperature 20 minutes
Afterwards, stirring is closed, deaeration: vacuumizing 3 minutes, until air pressure is -0.02MPa, keeps the temperature standing and defoaming 4.5 hours, obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 75 DEG C of glue box, is then opened
Open soft capsule host, glue made to flow out to 20 DEG C of temperature of cooling drum from glue box, be made rubber, rubber thickness in 0.75mm,
Capsule shells inner stuffing made from step 2 is added into the hopper of encapsulating machine simultaneously, adjustment sprinkler body temperature 60 C makes capsule clamping
Seam healing thickness meets the requirements, and can be suppressed after adjustment filling loading amount, soft capsule semi-finished product are made；
Step 5: being dried soft capsule semi-finished product made from step 4 to rubber moisture 11%, this is obtained
Invent masticable nutritional supplement soft capsule.
Control group 1
Prepare a kind of masticable nutritional supplement soft capsule, comprising the following steps:
Step 1: ingredient and weighing:
Number weighs according to the required weight: 5.5 parts of mushroom powder, 1.5 parts of spinach powder, newborn 5.5 parts of mineral salt, 1.5 parts of malt flour,
1.5 parts of milk powder, 4 parts of lactitol, 3.5 parts of mangosteen powder, remaining be 78 parts of olive oil, mushroom powder and spinach powder are respectively that mushroom is super
Micro- wall cell disruption powder and spinach super-micro wall-broken powder, and be new fresh mushroom and the spinach for being picked up choosing, it first arranges, clean respectively, boiling water heat
After cooking by scalding, then using under vacuum condition freeze-drying at water content is after 5% dehydration below is done, using micronizer powder
Average grain diameter is broken to 2 microns hereinafter, obtained mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder；
Number weighs capsule shells raw material: 60 parts of gelling agent hydroxypropul starch, 25 parts of lactose, microcrystalline cellulose according to the required weight
Element 11 parts, 6 parts of glucose, remaining be 110 parts of water and 20 parts of glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed mushroom powder of step 1, spinach powder, newborn mineral salt, malt
The form that powder, milk powder, lactitol, mangosteen powder, olive oil are uniformly mixed to capsule shells inner stuffing is solid gel, system
Obtain capsule shells inner stuffing；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 40 DEG C, then by hydroxypropul starch addition glue pot, lactose, crystallite are then added while stirring
After cellulose, glucose addition completely, it is further continued for heating and collosol temperature is raised between 100 DEG C, stop heating, keep the temperature 20 minutes
Afterwards, stirring is closed, deaeration: vacuumizing 3 minutes, until air pressure is -0.02MPa, keeps the temperature standing and defoaming 4.5 hours, obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 75 DEG C of glue box, is then opened
Open soft capsule host, glue made to flow out to 20 DEG C of temperature of cooling drum from glue box, be made rubber, rubber thickness in 0.75mm,
Capsule shells inner stuffing made from step 2 is added into the hopper of encapsulating machine simultaneously, adjustment sprinkler body temperature 60 C makes capsule clamping
Seam healing thickness meets the requirements, and can be suppressed after adjustment filling loading amount, soft capsule semi-finished product are made；
Step 5: being dried soft capsule semi-finished product made from step 4 to rubber moisture 11%, sought
Support replenishers soft capsule.
Control group 2
Prepare a kind of masticable nutritional supplement soft capsule, comprising the following steps:
Step 1: ingredient and weighing:
Number weighs according to the required weight: 15 parts of seawood meal, 1.5 parts of spinach powder, newborn 5.5 parts of mineral salt, 1.5 parts of malt flour,
1.5 parts of milk powder, 4 parts of lactitol, 3.5 parts of mangosteen powder, remaining be 78 parts of olive oil, seawood meal and spinach powder are respectively that seaweed is super
Micro- wall cell disruption powder and spinach super-micro wall-broken powder, and be new fresh seaweed and the spinach for being picked up choosing, it first arranges, clean respectively, boiling water heat
After cooking by scalding, then using under vacuum condition freeze-drying at water content is after 5% dehydration below is done, using micronizer powder
Average grain diameter is broken to 2 microns hereinafter, obtained seaweed super-micro wall-broken powder and spinach super-micro wall-broken powder；
Number weighs capsule shells raw material: 60 parts of gelling agent hydroxypropul starch, 25 parts of lactose, microcrystalline cellulose according to the required weight
Element 11 parts, 6 parts of glucose, remaining be 110 parts of water and 20 parts of glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, spinach powder, newborn mineral salt, malt
The form that powder, milk powder, lactitol, mangosteen powder, olive oil are uniformly mixed to capsule shells inner stuffing is solid gel, system
Obtain capsule shells inner stuffing；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 40 DEG C, then by hydroxypropul starch addition glue pot, lactose, crystallite are then added while stirring
After cellulose, glucose addition completely, it is further continued for heating and collosol temperature is raised between 100 DEG C, stop heating, keep the temperature 20 minutes
Afterwards, stirring is closed, deaeration: vacuumizing 3 minutes, until air pressure is -0.02MPa, keeps the temperature standing and defoaming 4.5 hours, obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 75 DEG C of glue box, is then opened
Open soft capsule host, glue made to flow out to 20 DEG C of temperature of cooling drum from glue box, be made rubber, rubber thickness in 0.75mm,
Capsule shells inner stuffing made from step 2 is added into the hopper of encapsulating machine simultaneously, adjustment sprinkler body temperature 60 C makes capsule clamping
Seam healing thickness meets the requirements, and can be suppressed after adjustment filling loading amount, soft capsule semi-finished product are made；
Step 5: being dried soft capsule semi-finished product made from step 4 to rubber moisture 11%, sought
Support replenishers soft capsule.
Control group 3
Prepare a kind of masticable nutritional supplement soft capsule, comprising the following steps:
Step 1: ingredient and weighing:
Number weighs according to the required weight: 15 parts of seawood meal, 5.5 parts of mushroom powder, newborn 5.5 parts of mineral salt, 1.5 parts of malt flour,
1.5 parts of milk powder, 4 parts of lactitol, 3.5 parts of mangosteen powder, remaining be 78 parts of olive oil, seawood meal and mushroom powder are respectively that seaweed is super
Micro- wall cell disruption powder and mushroom super-micro wall-broken powder, and be new fresh seaweed and the mushroom for being picked up choosing, it first arranges, clean respectively, boiling water heat
After cooking by scalding, then using under vacuum condition freeze-drying at water content is after 5% dehydration below is done, using micronizer powder
Average grain diameter is broken to 2 microns hereinafter, obtained seaweed super-micro wall-broken powder and mushroom super-micro wall-broken powder；
Number weighs capsule shells raw material: 60 parts of gelling agent hydroxypropul starch, 25 parts of lactose, microcrystalline cellulose according to the required weight
Element 11 parts, 6 parts of glucose, remaining be 110 parts of water and 20 parts of glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, mushroom powder, newborn mineral salt, malt
The form that powder, milk powder, lactitol, mangosteen powder, olive oil are uniformly mixed to capsule shells inner stuffing is solid gel, system
Obtain capsule shells inner stuffing；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 40 DEG C, then by hydroxypropul starch addition glue pot, lactose, crystallite are then added while stirring
After cellulose, glucose addition completely, it is further continued for heating and collosol temperature is raised between 100 DEG C, stop heating, keep the temperature 20 minutes
Afterwards, stirring is closed, deaeration: vacuumizing 3 minutes, until air pressure is -0.02MPa, keeps the temperature standing and defoaming 4.5 hours, obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 75 DEG C of glue box, is then opened
Open soft capsule host, glue made to flow out to 20 DEG C of temperature of cooling drum from glue box, be made rubber, rubber thickness in 0.75mm,
Capsule shells inner stuffing made from step 2 is added into the hopper of encapsulating machine simultaneously, adjustment sprinkler body temperature 60 C makes capsule clamping
Seam healing thickness meets the requirements, and can be suppressed after adjustment filling loading amount, soft capsule semi-finished product are made；
Step 5: being dried soft capsule semi-finished product made from step 4 to rubber moisture 11%, sought
Support replenishers soft capsule.
Control group 4
Prepare a kind of masticable nutritional supplement soft capsule, comprising the following steps:
Step 1: ingredient and weighing:
Number weighs according to the required weight: 15 parts of seawood meal, 5.5 parts of mushroom powder, 1.5 parts of spinach powder, newborn 5.5 parts of mineral salt,
1.5 parts of malt flour, 1.5 parts of milk powder, 4 parts of lactitol, remaining be 78 parts of olive oil, seawood meal, mushroom powder and spinach powder are respectively
Seaweed super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder, and be new fresh seaweed, mushroom and the spinach for being picked up choosing
Dish is first arranged respectively, is cleaned, after water blancing curing, then using freeze-drying under vacuum condition below for 5% at water content
After dehydration is dry, average grain diameter is crushed to 2 microns using micronizer hereinafter, obtained seaweed super-micro wall-broken powder, mushroom are super
Micro- wall cell disruption powder and spinach super-micro wall-broken powder；
Number weighs capsule shells raw material: 60 parts of gelling agent hydroxypropul starch, 25 parts of lactose, microcrystalline cellulose according to the required weight
Element 11 parts, 6 parts of glucose, remaining be 110 parts of water and 20 parts of glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, mushroom powder, spinach powder, newborn mineral
The form that salt, malt flour, milk powder, lactitol, olive oil are uniformly mixed to capsule shells inner stuffing is solid gel, is made
Capsule shells inner stuffing；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 40 DEG C, then by hydroxypropul starch addition glue pot, lactose, crystallite are then added while stirring
After cellulose, glucose addition completely, it is further continued for heating and collosol temperature is raised between 100 DEG C, stop heating, keep the temperature 20 minutes
Afterwards, stirring is closed, deaeration: vacuumizing 3 minutes, until air pressure is -0.02MPa, keeps the temperature standing and defoaming 4.5 hours, obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 75 DEG C of glue box, is then opened
Open soft capsule host, glue made to flow out to 20 DEG C of temperature of cooling drum from glue box, be made rubber, rubber thickness in 0.75mm,
Capsule shells inner stuffing made from step 2 is added into the hopper of encapsulating machine simultaneously, adjustment sprinkler body temperature 60 C makes capsule clamping
Seam healing thickness meets the requirements, and can be suppressed after adjustment filling loading amount, soft capsule semi-finished product are made；
Step 5: being dried soft capsule semi-finished product made from step 4 to rubber moisture 11%, sought
Support replenishers soft capsule.
Control group 5
Prepare a kind of masticable nutritional supplement soft capsule, comprising the following steps:
Step 1: ingredient and weighing:
Number weighs according to the required weight: 15 parts of seawood meal, 5.5 parts of mushroom powder, 1.5 parts of spinach powder, newborn 5.5 parts of mineral salt,
1.5 parts of malt flour, 4 parts of lactitol, 3.5 parts of mangosteen powder, remaining be 78 parts of olive oil, seawood meal, mushroom powder and spinach powder point
Not Wei seaweed super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder, and be the new fresh seaweed for being picked up choosing, mushroom
And spinach, first arrange, clean respectively, after water blancing curing, then use under vacuum condition freeze-drying at water content for 5% with
Under dehydration it is dry after, average grain diameter is crushed to 2 microns using micronizer hereinafter, obtain seaweed super-micro wall-broken powder, mushroom
Mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder；
Number weighs capsule shells raw material: 60 parts of gelling agent hydroxypropul starch, 25 parts of lactose, microcrystalline cellulose according to the required weight
Element 11 parts, 6 parts of glucose, remaining be 110 parts of water and 20 parts of glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, mushroom powder, spinach powder, newborn mineral
The form that salt, malt flour, lactitol, mangosteen powder, olive oil are uniformly mixed to capsule shells inner stuffing is solid gel,
Capsule shells inner stuffing is made；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol are first pumped into glue pot,
Stirring is opened, after being first warming up to 40 DEG C, then by hydroxypropul starch addition glue pot, lactose, crystallite are then added while stirring
After cellulose, glucose addition completely, it is further continued for heating and collosol temperature is raised between 100 DEG C, stop heating, keep the temperature 20 minutes
Afterwards, stirring is closed, deaeration: vacuumizing 3 minutes, until air pressure is -0.02MPa, keeps the temperature standing and defoaming 4.5 hours, obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 75 DEG C of glue box, is then opened
Open soft capsule host, glue made to flow out to 20 DEG C of temperature of cooling drum from glue box, be made rubber, rubber thickness in 0.75mm,
Capsule shells inner stuffing made from step 2 is added into the hopper of encapsulating machine simultaneously, adjustment sprinkler body temperature 60 C makes capsule clamping
Seam healing thickness meets the requirements, and can be suppressed after adjustment filling loading amount, soft capsule semi-finished product are made；
Step 5: being dried soft capsule semi-finished product made from step 4 to rubber moisture 11%, sought
Support replenishers soft capsule.
Masticable nutritional supplement plant soft of the invention is further illustrated below by human experiment laboratory report
The mouthfeel and effect of capsule.
1. tested material and study subject
(1) tested material: by 1~embodiment of the embodiment of the present invention 5 the masticable nutrition produced to preparation method mend
Filling agent soft capsule is laboratory sample, 1~control group of control group 5 the nutritional supplement plant soft produced to preparation method
Capsule sample as a control group, wherein the given preparation method parameter of 1~control group of control group 5 and the given preparation method of embodiment 5
Parameter is identical, compared with Example 5 its only raw material components are different, be not added seawood meal in control group 1 wherein, in control group 2 not
Mushroom powder is added, spinach powder is not added in control group 3, mangosteen powder is not added in control group 4, milk powder is not added in control group 5.
(2) study subject: subject 220 for randomly choosing 12-52 years old by the principle of voluntariness are used as the person of foretasting.
2. test method and result
(1) test method
The masticable nutritional supplement soft capsule of the present invention, through detecting lead content, total arsenic, copper, benzoic acid, sunset
Huang, lemon yellow, dehydroactic acid, Sucralose, saccharin sodium, honey element (in terms of cyclohexylsulfamic), acetyl para-aminobenzenesulfonic acid potassium (peace
Match honey), amaranth, brilliant blue items testing result be be not detected；Total plate count, coliform, mould, yeast, pathogenic bacteria are (husky
Door Salmonella, staphylococcus aureus etc.) every testing result meets the requirements of the standard；Its nutrition content, which complies with standard, to be wanted
It asks, edible safety.
Stochastic averagina is divided into 11 groups, and every group of difference daily sooner or later each 1 particle test sample after 1 month time, is mended each nutrition
The appearance smell and oral situation for filling agent soft capsule are given a mark,
Standard is as follows:
8~10 points: it is in good taste, it easily swallows, no disagreeable taste；
4~7 points: mouthfeel can receive, and can swallow, and disagreeable taste can receive；
1~3 point: poor taste, it is difficult to swallow, disagreeable taste is serious；
It the results are shown in Table 1.
The pilot project and result of 1 nutritional supplement soft capsule performance of table
By pilot project and the result of 1 nutritional supplement soft capsule performance of table it is found that pressing the embodiment of the present invention 1~reality
Apply example 5 the masticable nutritional supplement soft capsule produced to preparation method be laboratory sample, overall appearance feel
Good toughness, transparency is high, no bad smell, and whole storage investigates result and knows that its corrosion-resistant stability is good；It is in good taste, easily gulp down
Pharynx, no disagreeable taste, seawood meal, mushroom powder, spinach powder, newborn mineral salt, malt flour, milk powder, olive oil, lactitol, Siraitia grosvenorii
Powder makes as capsule shells content, gelling agent hydroxypropul starch, lactose, microcrystalline cellulose, glucose as rubber powder ingredient
Capsule shells, capsule shells content and capsule shells mutually act synergistically, and make capsule more Q bullet obtained, and glittering and translucent, high transparency
Degree.Long-term use can supplement, a variety of nutriments of needed by human body.
1~control group of control group 5 the nutritional supplement soft capsule produced to preparation method sample as a control group
Product, wherein the given preparation method parameter of 1~control group of control group 5 is identical as the given preparation method parameter of embodiment 5, with embodiment
5 compare it, and only raw material components are different, and seawood meal is not added in control group 1 wherein, mushroom powder, control group 3 is not added in control group 2
In spinach powder is not added, mangosteen powder is not added in control group 4, milk powder is not added in control group 5, by 1 data result of table it is found that
Seawood meal, mushroom powder, spinach powder, milk powder and mangosteen powder synergistic effect, cover respective bad smell, while making capsule shells
The form of inner stuffing becomes solid gel shape, further synergistic with capsule shells, improves the masticable nutrition of the present invention and mends
The appearance good toughness of agent soft capsule is filled, transparency is high, no bad smell, and Q bullet sense significantly improves in mouthfeel, meets people's
Mouthfeel demand.
3. conclusion
Masticable nutritional supplement soft capsule prepared by the present invention, to temperature and humidity stability height, good toughness and height
The product of transparency.Seawood meal, mushroom powder, spinach powder, newborn mineral salt, malt flour, milk powder, olive oil, lactitol, mangosteen powder
As capsule 's content, it is added on the basis of original natural plant gum hydroxypropul starch after lactose, microcrystalline cellulose, glucose significantly
Enhance capsule chewiness, makes capsule more Q bullet, hide bad smell；Seawood meal, newborn mineral salt adds that have capsule high together
The effect of calcium, remarkably promotes the calcareous absorption of human body, needed for supplementing body, and it is not excessive.Hydroxypropyl used in the present invention forms sediment
Powder is one of most commonly used converted starch of Applications in Food Industry；Due to introducing a certain number of hydroxyls on starch molecule
Group, destroys the surface texture of starch granules, so that hydroxypropul starch particle is compared with ative starch with being easy by salivaryα-amylase water
Solution, increases degree of substitution, accelerates digestion rate, and the digestic property of particle improves；It is effectively improved the property of gelatinized corn starch simultaneously, increases
The hydrophily and water retention property of strong gelatinized corn starch, increase the transparency of gelatinized corn starch and stability, are not easy to precipitate, good film-forming property has
Toughness；There is the above advantageous property based on hydroxypropul starch, the present invention is used for the raw material of soft capsule.
The method of masticable nutritional supplement soft capsule prepared by the present invention, is handled, more preferably using distinct temperature
Dissolve rubber powder, can reach transparency and significantly improve, and further cover content itself peculiar smell effect.Seaweed
Powder is to be aided with a small amount of marine microalgae retrofit using marine natural seaweed as major ingredient and form.Natural seaweed powder rich in algal polysaccharides,
The microelements such as mannitol, amino acid, protein, vitamin and potassium, iron, calcium, phosphorus, iodine, selenium, cobalt.The surface of seaweed has one layer
Extremely wet mucus protects seaweed surface after being mainly used for ebb, prevents solarization from excessively causing death.According to this original
Reason, people study this layer of mucus, it is found that it is a kind of polysaccharose substance, have fabulous ductility, super oxygen
Object mutase can prevent the activation of the skin surface oxidation factor as caused by excessive solarization, can also extract in seaweed
This enzyme out.The a large number of nutrients such as protein, amino acid, carbohydrate, vitamin and mineral can in natural seaweed powder
Immune system is improved, strong bone is reinforced physical efficiency and endurance, resisted the disease.Mushroom is full of nutrition, is selenium, copper, potassium, phosphorus, color ammonia
The excellent food source of acid and vitamin B2, B3, B5.Zinc, manganese, magnesium, iron, calcium and protein and vitamin B1 are also rich in mushroom
With B6, folic acid, dietary fiber etc..Mushroom powder is exactly by the finished product of dried mushrooms processing powdering.(1) immunity of organisms, mushroom are improved
The effective component of mushroom can enhance T lymphocyte function, to improve the immunity that body resists various diseases.(2) analgesia, town
It is quiet.(3) relieving cough and reducing sputum said mushroom extract zoopery finds that it plays the role of apparent antibechic, desaturation sputum.(4) defaecation
It is difficult to the crude fibre digested, half crude fibre and lignin containing human body in toxin expelling mushroom, enteral water balance can be kept, can also be inhaled
Remaining cholesterol, sugar are received, is discharged it in vitro, it is all highly beneficial to prevent constipation, intestinal cancer, artery sclerosis, diabetes etc..
(5) promote appetite mushroom that can also control and accompany the diseases such as leukopenia, digestive disorder；To promote appetite, restore cerebral function,
Galactosis is promoted to have certain booster action.Spinach has the title of " nutrition model student ", it rich in carotenoid, vitamin C,
The various nutrients such as vitamin K, minerals (calcareous, irony etc.), Co-Q10.In soft capsule shell content of the invention
It is after spinach to be cooked by scalding to life, after oxalic acid therein is destroyed, while retaining its ingredient, by the green of spinach using spinach powder
Color is mixed with milk powder, then is combined with the nutritional ingredient of seawood meal and mushroom powder with mouthfeel elasticity etc., is acted synergistically, is made
Masticable nutritional supplement soft capsule produced by the present invention not only free from extraneous odour, hides bad smell, while significantly mentioning
Its high chewiness, Q bullet is tasty and refreshing, in good taste, easily swallows, and no disagreeable taste is easy to be accepted, convenient, when in need
Supplement multivitamin and nutriment crowd can masticable nutritional supplement soft capsule through the invention, both
Meet mouthfeel, and supplements nutriment.
Seawood meal, mushroom powder and spinach powder are respectively that seaweed super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach ultra micro are broken
Wall powder can further be such that the synergistic effect of seawood meal, mushroom powder, spinach powder, milk powder and mangosteen powder further shows
Come, further increase the smooth and fine and smooth sense of mouthfeel, meets the mouth feeling experience of people's pursuit.
In summary, the present invention prepares masticable nutritional supplement soft capsule, and nutrition is comprehensive, ratio is scientific, function
The bioavailability of the energy factor is high, and stable in physicochemical property, securely and reliably, and materials are simple, and efficacy exertion ability more generally produces
Product are strong, significant in efficacy, are easily absorbed by the body, and absorption rate is high；Production cost is low, and production method is continuously uninterrupted, mentions significantly
High efficiency has great economic benefit.With common gelatin soft capsule shell phase ratio, common soft-gelatin softgel shell main component
For protein, microorganism easy to breed, soft capsule after the shell dries moisture, it is easier to save not cooperating microorganisms；This hair
Light adaptation is wide, high without cross-linking reaction risk, stability, can take together with many drugs, high safety and reliability, in human body
It being easily absorbed after disintegration, accelerates digestion rate, the digestic property of particle improves, under high humidity condition of storage, present invention preparation
The indices of masticable nutritional supplement soft capsule are more advantageous compared to common gelatin soft capsule.
Only as described above, only specific embodiments of the present invention, when the model that cannot be limited the present invention with this and implement
It encloses, it is all according to equivalent changes and modifications within the scope of the patent application of the present invention, it is all covered by the present invention.
Claims (10)
1. a kind of masticable nutritional supplement soft capsule, which is characterized in that according to parts by weight, capsule shells inner stuffing
Raw material includes following components: 10-20 parts of seawood meal, 1-10 parts of mushroom powder, 1-2 parts of spinach powder, newborn 1-10 parts of mineral salt, malt flour
1-2 parts, 1-2 parts of milk powder, 2-6 parts of lactitol, 0.1-6 parts of mangosteen powder, remaining be olive oil 40-82.9 parts；The capsule shells
Raw material include gelling agent and plasticizer, and the gelling agent is hydroxypropul starch, the plasticizer be lactose, microcrystalline cellulose,
Glucose any of which is several.
2. a kind of masticable nutritional supplement soft capsule according to claim 1, which is characterized in that the seaweed
Powder, mushroom powder and spinach powder are respectively seaweed super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder, and be through
New fresh seaweed, mushroom and the spinach of choosing are picked up, first arranges, clean respectively, after water blancing curing, then using and freezed under vacuum condition
Being dried to water content is to be crushed to average grain diameter to 2 microns hereinafter, obtaining using micronizer after 5% dehydration below is dry
Seaweed super-micro wall-broken powder, mushroom super-micro wall-broken powder and spinach super-micro wall-broken powder.
3. a kind of masticable nutritional supplement soft capsule according to claim 1, which is characterized in that by weight
Number meter, the capsule shells inner stuffing raw material include following components: 12-18 parts of seawood meal, 3-8 parts of mushroom powder, spinach powder 1.5
Part, newborn 3-8 part of mineral salt, 1-2 parts of malt flour, 1-2 parts of milk powder, 2-6 parts of lactitol, 0.1-6 parts of mangosteen powder, remaining be olive
It is 60-82.9 parts oily.
4. a kind of masticable nutritional supplement soft capsule according to claim 1, which is characterized in that by weight
Number meter, the capsule shell material includes 40-80 parts of hydroxypropul starch, 10-40 parts of lactose, 1-20 parts of microcrystalline cellulose, glucose
1-10 parts, remaining be water 100-120 parts and 10-30 parts of glycerol.
5. a kind of masticable nutritional supplement soft capsule according to claim 1, which is characterized in that the capsule
Thickness of the shell is 0.35~1.00mm.
6. a kind of production side of masticable nutritional supplement soft capsule described in -5 any one according to claim 1
Method, which comprises the following steps:
Step 1: ingredient and weighing: number weighs according to the required weight: seawood meal, mushroom powder, spinach powder, newborn mineral salt, malt
Powder, milk powder, lactitol, mangosteen powder, olive oil；Number weighs capsule shells raw material: hydroxypropul starch, cream according to the required weight
Sugar, microcrystalline cellulose, glucose, remaining be water and glycerol；
Step 2: the preparation of capsule shells inner stuffing: by the weighed seawood meal of step 1, mushroom powder, spinach powder, newborn mineral salt,
Malt flour, milk powder, lactitol, mangosteen powder, olive oil are uniformly mixed, and capsule shells inner stuffing is made；
Step 3: the preparation (changing glue) of capsule shells glue: the weighed part water of step 1 and glycerol being first pumped into glue pot, opened
After being first warming up to 35-45 DEG C, then by hydroxypropul starch addition glue pot, it is fine that lactose, crystallite is then added in stirring while stirring
It after dimension element, glucose addition completely, is further continued for heating and collosol temperature is raised between 95-105 DEG C, stop heating, after heat preservation, close
Stirring is closed, deaeration obtains glue；
Step 4: compacting soft capsule: glue made from step 3 being delivered to and has been kept the temperature into 60~95 DEG C of glue box, is then opened
Soft capsule host is opened, so that glue is flowed out to 15~25 DEG C of temperature of cooling drum from glue box, rubber is made, rubber thickness is 0.35
~1.00mm, while capsule shells inner stuffing made from step 2 being added into the hopper of encapsulating machine, adjust sprinkler body temperature 35
~70 DEG C make capsule crack healing thickness meet the requirements, and can be suppressed after adjustment filling loading amount, soft capsule half is made
Finished product；
Step 5: obtaining the masticable nutrition of the present invention after soft capsule semi-finished product made from step 4 are dried and mending
Fill agent soft capsule.
7. a kind of production method of masticable nutritional supplement soft capsule according to claim 6, feature exist
In in step 2, the form for being uniformly mixed to the capsule shells inner stuffing is solid gel.
8. a kind of production method of masticable nutritional supplement soft capsule according to claim 6, feature exist
In, in step 3, it is described be first warming up to 40 DEG C after, then will hydroxypropul starch be added glue pot in.
9. a kind of production method of masticable nutritional supplement soft capsule according to claim 6, feature exist
In in step 3, the soaking time is after twenty minutes, to close stirring, the deaeration step are as follows: vacuumize 3 minutes, until air pressure
For -0.02MPa, standing and defoaming 4-5 hours is kept the temperature.
10. a kind of production method of masticable nutritional supplement soft capsule according to claim 6, feature exist
In further including Step 5: dry: the soft capsule semi-finished product of step 4 compression moulding are dry to rubber moisture 7~15%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910179459.5A CN109846849A (en) | 2019-03-11 | 2019-03-11 | A kind of masticable nutritional supplement soft capsule and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910179459.5A CN109846849A (en) | 2019-03-11 | 2019-03-11 | A kind of masticable nutritional supplement soft capsule and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109846849A true CN109846849A (en) | 2019-06-07 |
Family
ID=66900427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910179459.5A Pending CN109846849A (en) | 2019-03-11 | 2019-03-11 | A kind of masticable nutritional supplement soft capsule and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109846849A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111543624A (en) * | 2020-05-11 | 2020-08-18 | 上海互众药业有限公司 | Anti-adhesion soft rubber, soft capsule and preparation method thereof |
| CN117562868A (en) * | 2024-01-17 | 2024-02-20 | 广东臻品健康科技有限公司 | DHA algae oil soft capsule and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375229A (en) * | 2017-06-26 | 2017-11-24 | 仙乐健康科技股份有限公司 | One kind chews soft capsule and preparation method thereof |
| CN108041607A (en) * | 2017-12-26 | 2018-05-18 | 广州普正生物科技有限公司 | A kind of shield tooth probiotics chewing soft capsule |
-
2019
- 2019-03-11 CN CN201910179459.5A patent/CN109846849A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375229A (en) * | 2017-06-26 | 2017-11-24 | 仙乐健康科技股份有限公司 | One kind chews soft capsule and preparation method thereof |
| CN108041607A (en) * | 2017-12-26 | 2018-05-18 | 广州普正生物科技有限公司 | A kind of shield tooth probiotics chewing soft capsule |
Non-Patent Citations (4)
| Title |
|---|
| 关志宇: "《药物制剂辅料与包装材料》", 31 January 2017, 中国医药科技出版社 * |
| 宁莉等主编: "《公共营养师 上册》", 31 March 2015, 辽宁科学技术出版社 * |
| 李捷玮等主编: "《常用药物辅料手册》", 30 June 2000, 第二军医大学出版社 * |
| 郑坚强: "《食品感官评定》", 31 January 2013, 中国科学技术出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111543624A (en) * | 2020-05-11 | 2020-08-18 | 上海互众药业有限公司 | Anti-adhesion soft rubber, soft capsule and preparation method thereof |
| CN117562868A (en) * | 2024-01-17 | 2024-02-20 | 广东臻品健康科技有限公司 | DHA algae oil soft capsule and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102511720B (en) | Stachyose infant nourishing cereal and its preparation method | |
| CN108618129A (en) | Sarcopenia tailored version clinical nutrition formula and preparation method thereof | |
| CN106962946B (en) | Method for constructing grain-like structure with slow digestibility | |
| CN104366480A (en) | Lipid-lowering and weight-reducing nutritional meal powder and preparation method thereof | |
| CN103519009B (en) | Healthcare sand for pigeons | |
| CN101731622A (en) | Lucid ganoderma spirulina tablet and preparation process thereof | |
| CN105028865A (en) | Moringa oleifera and moringa oleifera dextrose candy and preparation | |
| JP2018519337A (en) | Method for producing fermented mineral raw pills having a function of improving constipation and fatigue recovery, and fermented mineral raw pills produced thereby | |
| CN102987163A (en) | Immune-enhancing feed and preparation method thereof | |
| CN109965073A (en) | A kind of gel candy of stomach strengthening and digestion promoting and preparation method thereof | |
| CN109846849A (en) | A kind of masticable nutritional supplement soft capsule and preparation method thereof | |
| CN104431625A (en) | Feed formula for improving immunities of piglets | |
| CN103947871A (en) | Meet goose compound feed and preparation method thereof | |
| CN104323093A (en) | Stomach-invigorating digestion-helping eight-ingredient porridge and preparation method thereof | |
| CN105266140A (en) | Processing method of hericium erinaceus composite capsule | |
| CN104957474A (en) | Moringa oleifera composition for reducing blood pressure and preparation method of moringa oleifera composition | |
| CN107259135A (en) | A kind of processing method of cattle feed | |
| CN104366054A (en) | Feed of rabbit suitable for diabetics to eat | |
| CN103875969A (en) | Nutrient feed for hairtail and preparation method thereof | |
| CN105166620A (en) | Horseradish tree composition capable of reducing blood lipid and preparation method of horseradish tree composition | |
| CN109497470A (en) | A kind of chlorella pyrenoidosa polypeptide alleviates getting fat composition and preparation method thereof | |
| CN102150779B (en) | Health food for regulating and stabilizing blood sugar and preparation method thereof | |
| CN101797049B (en) | Nutrient eight-treasure soup formula and preparation process thereof | |
| CN109601976A (en) | It is suitble to the functional food of tumor patients | |
| CN101120750A (en) | Method for preparing ginkgo bee product |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190607 |