CN109832397A - Sweet wormwood pressed candy and preparation method thereof - Google Patents
Sweet wormwood pressed candy and preparation method thereof Download PDFInfo
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- CN109832397A CN109832397A CN201711212744.XA CN201711212744A CN109832397A CN 109832397 A CN109832397 A CN 109832397A CN 201711212744 A CN201711212744 A CN 201711212744A CN 109832397 A CN109832397 A CN 109832397A
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- sweet wormwood
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- early teens
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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Abstract
A kind of sweet wormwood pressed candy and preparation method thereof, it includes effective component be sweet wormwood, honeysuckle, in one's early teens, cape jasmine and dried orange peel, weight ratio be 40:10:10:10:1~6:2:2:2:1.The present invention can reduce raw material usage amount by synergistic function, reduce side effect;The effect of prevention of malaria, prevention dengue fever, heat-clearing, sunstroke prevention, protect liver, diuresis can be played, and not will lead to drug resistance problems.
Description
Technical field
The present invention relates to a kind of technology of field of health care food, specifically a kind of sweet wormwood tabletting with health-care efficacy
Sugar and preparation method thereof, including primary raw material be sweet wormwood, honeysuckle, in one's early teens, cape jasmine, dried orange peel etc..
Background technique
Prevention of malaria can avoid bite by mosquitos by mosquito net and mosquito repellent liquid, it is also possible to chemoprophylaxis, common prophylactic agent
It is sulfamethoxine/Billy's U.S. amine, but chemoprophylaxis has bigger adverse reaction, the compliance of people is poor.Pass through daily zero
Food prevention has relatively good effect.
Summary of the invention
The present invention In view of the above shortcomings of the prior art, proposes a kind of sweet wormwood pressed candy and preparation method thereof, pass through
Synergistic function can reduce raw material usage amount, reduce side effect;Prevention of malaria can be played, prevention dengue fever, heat-clearing, prevented
The effect of heat, protect liver, diuresis, and not will lead to drug resistance problems.
The present invention is achieved by the following technical solutions:
The present invention relates to a kind of composition for prevention of malaria, comprising effective component be sweet wormwood, honeysuckle, in one's early teens,
Cape jasmine and dried orange peel, further preferred sweet wormwood, honeysuckle, in one's early teens, cape jasmine, dried orange peel weight ratio be 40:10:10:10:1~6:
2:2:2:1;It is furthermore preferred that sweet wormwood in the composition, honeysuckle, in one's early teens, cape jasmine, dried orange peel weight ratio be 20:5:5:5:1.
The present invention relates to a kind of sweet wormwood pressed candy with health-care efficacy, raw material components and mass ratio include: 20-50 parts
Sweet wormwood, 2-20 portions of honeysuckles, 2-20 parts in one's early teens, 2-20 portions of cape jasmines, 0.5-5 parts of dried orange peels, 8-15 parts of dextrin, 8-15 parts of sorboses
Alcohol, 0.08-0.15 part hydroxymethyl-propyl cellulose, 0.08-0.15 parts of magnesium stearates, 0.04-0.08 parts of Aspartames, 0.01-
0.05 part of edible essence.
The sweet wormwood pressed candy, raw material form by percentage to the quality, comprising: 20-50% sweet wormwood, 2-20% gold and silver
Flower, 2-20% in one's early teens, 2-20% cape jasmine, 0.5-5% dried orange peel, 8-15% dextrin, 8-15% D-sorbite, 0.08-0.15%
Hydroxymethyl-propyl cellulose, 0.08-0.15% magnesium stearate, 0.04-0.08% Aspartame, 0.01-0.05% edible essence;
It is preferred that its raw material composition include 40% sweet wormwood, 10% honeysuckle, 10% in one's early teens, 10% cape jasmine, 2% dried orange peel, 13% dextrin,
13% D-sorbite, 0.13% hydroxymethyl-propyl cellulose, 0.13% magnesium stearate, 0.06% Aspartame, 0.03% are eaten
Essence.
The sweet wormwood is derived from sweet wormwood blade;It is preferred that being derived from sweet wormwood cured leaf of the artemislnin content 0.8% or more.
The sweet wormwood, honeysuckle, in one's early teens, cape jasmine, the raw materials such as dried orange peel be processed to granular size at 25-250 microns
Between fine powder, be conducive to preferably be dispersed in pressed candy, also be conducive to human body quickly absorb effective component therein.
The present invention relates to the preparation method of above-mentioned sweet wormwood pressed candy, by will be in the raw material components of the sweet wormwood pressed candy
Effective component is crushed adds water to mix with after dextrin, D-sorbite and Aspartame, and hydroxymethyl-propyl cellulose ethanol solution is added
After particle is made, be dried to obtain after drying with after magnesium stearate and edible essence total mix through tabletting.
The method specifically includes the following steps:
The preparation of step 1) softwood: 20-50 parts of sweet wormwood powders, 2-20 parts of honeysuckle powders, 2-20 parts of powder, 2-20 part in one's early teens are taken
Gardenia powder, 0.5-5 part tangerine peel powder, 8-15 parts of dextrin, 8-15 parts of D-sorbites and 0.04-0.08 parts of Aspartame mixing, add few
Measure water wet mix;The hydroxymethyl-propyl cellulose ethanol solution of 0.08-0.15% is prepared as wetting agent, is mixed with raw material
Object is closed by mixing well in equal volume.
The sweet wormwood, honeysuckle, in one's early teens, cape jasmine and tangerine peel powder cross 200 meshes respectively after low temperature is milled.
The dextrin, D-sorbite, hydroxymethyl-propyl cellulose, magnesium stearate, Aspartame and edible essence are direct
Cross 200 meshes.
Step 2) is granulated and drying: particle is made through 20 meshes in softwood;By particle after 40-60 DEG C of wind-heat is dry, add
Enter 0.08-0.15 parts of magnesium stearates and 0.01-0.05 parts of edible essences and particle carries out total mix, selects whole grain through 60 meshes.
Step 3) compression molding: carrying out compression molding through rotary pelleting machine for total mix particle, make tablet weight 0.25~
0.35g, hardness is suitable for, and disintegration meets the requirements.Shaping is carried out after tabletting, sterilizes and be packaged to be sweet wormwood pressed candy.
Technical effect
Compared with prior art, sweet wormwood pressed candy of the present invention can with prevention of malaria, dengue fever, and can with heat-clearing, sunstroke prevention,
Protect liver and diuresis and other effects.The people for being particularly suitable for the tropical and subtropical region such as Africa, Southeast Asia are edible, or plan enters
This area's travelling, study, the crowd of work are edible.Sweet wormwood, honeysuckle, cape jasmine are cold in nature, in one's early teens warm-natured with dried orange peel in pressed candy,
Several main components complement each other, and can have the function of synergy.D-sorbite and Aspartame in pressed candy replace sugarcane
It is bitter effectively to cover sweet wormwood, while will not cause blood glucose rise for sugar, and suitable population is wide, and the peppermint of addition can increase refrigerant mouthfeel,
It is suitable for being eaten in hot, wet bored area.Above-mentioned sweet wormwood pressed candy, can also add other suitable auxiliary materials be made thoat-soothing drops,
It is coated other candy forms such as sugar, chewing gum.
Detailed description of the invention
Fig. 1 is schematic diagram of the process of the invention.
Fig. 2 is the antiplasmodial cell experiment result figure of sweet wormwood pressed candy.
Specific embodiment
Embodiment 1
The present embodiment the following steps are included:
The crushing of step 1) raw material: take 40 portions of sweet wormwoods, 10 portions of honeysuckles, 10 parts in one's early teens, 10 portions of cape jasmines and 2 parts of dried orange peel originals
Material, is milled through low temperature, crosses 200 meshes;13 parts of dextrin, 13 parts of D-sorbites, 0.13 part of hydroxymethyl-propyl cellulose, 0.13 part it is hard
Fatty acid magnesium, 0.06 part of Aspartame and direct 200 mesh of mistake of 0.03 part of edible essence.
The preparation of step 2) softwood: 40 parts of sweet wormwood powders, 10 parts of honeysuckle powders, 10 parts of powder, 10 parts of gardenia powders, 2 in one's early teens are taken
Part tangerine peel powder, 13 parts of dextrin, 13 parts of D-sorbites and 0.06 part of Aspartame mixing, add a small amount of water wet mix;Preparation
0.13% hydroxymethyl-propyl cellulose ethanol solution is as wetting agent, with mixture of raw material by mixing well in equal volume.
Step 3) is granulated and drying: particle is made through 20 meshes in softwood obtained by step 2);Particle is done through 50 DEG C of wind-heat
After dry, 0.13 part of magnesium stearate and 0.03 part of edible essence is added and particle carries out total mix, selects whole grain through 60 meshes.
Step 4) compression molding: carrying out compression molding through rotary pelleting machine for total mix particle, make tablet weight 0.25~
0.35g, hardness is suitable for, and disintegration meets the requirements.After tabletting carry out shaping, sterilize and be packaged to be product, that is, have health care,
The sweet wormwood pressed candy of antimalarial effect.
Embodiment 2
The antiplasmodial cell experiment of sweet wormwood pressed candy
By sweet wormwood, honeysuckle, in one's early teens, the sweet wormwood pressed candy that makes in various combination ratio of cape jasmine, dried orange peel mentions through ultrasound
It takes, 100 μM of mother liquor is configured to DMS, be diluted to 1 μM with culture medium later and filter spare.Medicine sieves 200 μ L of total volume, and 100
μ L is prepared for drug concentration gradient, and 100 μ L are for preparing plasmodium system.Final drug concentration is since 200nm, dilution 10
A gradient, plasmodium starting parasite rate is 1% in total system, hematocrit 2%.Not dosing is used as negative control, is not added
Plasmodium only adds red blood cell as background.After system prepares completion, 37 DEG C of three air culture is supported 72 hours.100 μ L lysates are added
(0.05%SYBR Green) is mixed, and is incubated at room temperature 2 hours, is read fluorescent value (485/535) later.Malaria is calculated according to result
Protozoon survival rate is as shown in Fig. 2.The results show that sweet wormwood, honeysuckle, in one's early teens, cape jasmine, dried orange peel composite components antimalarial effect
Be significantly higher than the antimalarial effect of one-component, wherein sweet wormwood, honeysuckle, in one's early teens, cape jasmine, dried orange peel press its weight ratio 20:5:5:
The component of 5:1 has optimal antimalarial effect.
Embodiment 3
The edible health effect of sweet wormwood pressed candy is tested and assessed
100 people of each age groups of Southeast Asia tourism is gone in selection, wherein the 40 of 6-20 years old, and 30 of 20-55 years old, 55-
40 of 70 years old give the pressed candy for being lower than 1g for each person every day.There is vomiting, fever, loss of appetite phenomenon in effect evaluating standard
It is invalid.
Table 1: the edible health effect evaluating result of sweet wormwood pressed candy
6-20 years old | 20-55 years old | 55-70 years old | |
Effectively | 28 | 30 | 27 |
In vain | 2 | 0 | 3 |
Experimental result is shown, by eating sweet wormwood pressed candy, torrid areas warm and bite by mosquitos can be effectively relieved
The common symptons such as caused heatstroke, fever, vomiting, loss of appetite.
Above-mentioned specific implementation can by those skilled in the art under the premise of without departing substantially from the principle of the invention and objective with difference
Mode carry out local directed complete set to it, protection scope of the present invention is subject to claims and not by above-mentioned specific implementation institute
Limit, each implementation within its scope is by the constraint of the present invention.
Claims (15)
1. a kind of composition for prevention of malaria, which is characterized in that comprising effective component be sweet wormwood, honeysuckle, in one's early teens, Cape jasmine
Son and dried orange peel.
2. composition according to claim 1, it is characterised in that: the sweet wormwood, honeysuckle, in one's early teens, cape jasmine, dried orange peel
Weight ratio is 40:10:10:10:1~6:2:2:2:1.
3. composition according to claim 1, characterized in that sweet wormwood in composition, honeysuckle, in one's early teens, cape jasmine, dried orange peel
Weight ratio be 20:5:5:5:1.
4. a kind of sweet wormwood pressed candy with health-care efficacy, which is characterized in that its raw material components and mass ratio include: 20-50 parts
Sweet wormwood, 2-20 portions of honeysuckles, 2-20 parts in one's early teens, 2-20 portions of cape jasmines, 0.5-5 parts of dried orange peels, 8-15 parts of dextrin, 8-15 parts of sorboses
Alcohol, 0.08-0.15 part hydroxymethyl-propyl cellulose, 0.08-0.15 parts of magnesium stearates, 0.04-0.08 parts of Aspartames, 0.01-
0.05 part of edible essence.
5. sweet wormwood pressed candy according to claim 4, characterized in that its raw material optimized composition and mass ratio are as follows: 40 parts
Sweet wormwood, 10 portions of honeysuckles, 10 parts in one's early teens, 10 portions of cape jasmines, 2 parts of dried orange peels, 13 parts of dextrin, 13 parts of D-sorbites, 0.13 part of hydroxyl first
Base propyl cellulose, 0.13 part of magnesium stearate, 0.06 part of Aspartame, 0.03 part of edible essence.
6. any sweet wormwood pressed candy, feature in composition according to claims 1 to 3 or claim 4~5
It is the sweet wormwood, is derived from sweet wormwood cured leaf of the artemislnin content 0.8% or more.
7. a kind of preparation method for preparing any sweet wormwood pressed candy in claim 4~5, which is characterized in that by by institute
Stating the effective component in the raw material components of sweet wormwood pressed candy and crushing adds water to mix with after dextrin, D-sorbite and Aspartame, adds
Particle is made after entering hydroxymethyl-propyl cellulose ethanol solution, after drying with after magnesium stearate and edible essence total mix through tabletting
It is dried to obtain.
8. according to the method described in claim 7, it is characterized in that, specifically includes the following steps:
The preparation of step 1) softwood: 20-50 parts of sweet wormwood powders, 2-20 parts of honeysuckle powders, 2-20 portions of powder, 2-20 portions of cape jasmines in one's early teens are taken
Powder, 0.5-5 part tangerine peel powder, 8-15 parts of dextrin, 8-15 parts of D-sorbites and 0.04-0.08 parts of Aspartame mixing, add a small amount of water
Wet mix;The hydroxymethyl-propyl cellulose ethanol solution of 0.08-0.15% is prepared as wetting agent, with mixture of raw material
By mixing well in equal volume;
Step 2) is granulated and drying: particle is made through 20 meshes in softwood;By particle after 40-60 DEG C of wind-heat is dry, it is added
0.08-0.15 parts of magnesium stearates and 0.01-0.05 parts of edible essences and particle carry out total mix, select whole grain through 60 meshes;
Step 3) compression molding: carrying out compression molding through rotary pelleting machine for total mix particle, make tablet weight 0.25~
0.35g carries out shaping, sterilizes and be packaged to be sweet wormwood pressed candy after tabletting.
9. method according to claim 7 or 8, characterized in that the sweet wormwood, honeysuckle, in one's early teens, cape jasmine and dried orange peel
Powder crosses 200 meshes respectively after low temperature is milled.
10. method according to claim 7 or 8, characterized in that the dextrin, D-sorbite, hydroxymethylpropyl fiber
Element, magnesium stearate, Aspartame and direct 200 mesh of mistake of edible essence.
11. the guarantor that composition according to claims 1 to 3 is used for prevention of malaria, dengue fever and liver protection diuresis in preparation
Purposes in strong product.
12. application of the composition described in claims 1 to 3 in production food, health care product and drug.
13. being used for prevention of malaria, dengue fever, Yi Jibao in preparation according to the sweet wormwood pressed candy any in claim 4~7
Purposes in the health care product of liver diuresis.
14. according to the sweet wormwood pressed candy answering in production food, health care product and drug any in claim 4~10
With.
15. according to the sweet wormwood pressed candy of the preparation method preparation any in claim 4-10 in production food, health care product
With the purposes in drug.
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CN201711212744.XA CN109832397A (en) | 2017-11-28 | 2017-11-28 | Sweet wormwood pressed candy and preparation method thereof |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110293704A (en) * | 2019-07-03 | 2019-10-01 | 蚌埠学院 | A kind of preparation method and its preforming device of Yunnan olive pressed candy |
CN112494590A (en) * | 2020-07-14 | 2021-03-16 | 蚌埠学院 | Traditional Chinese medicine liquor for preventing and treating new coronary pneumonia |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1876045A (en) * | 2003-01-08 | 2006-12-13 | 江苏康缘药业股份有限公司 | A Chinese medicinal composition, its preparation process and quality control method |
CN107372998A (en) * | 2017-08-23 | 2017-11-24 | 苏州唐基生物科技有限公司 | Sweet wormwood sugar with health-care efficacy and preparation method thereof |
-
2017
- 2017-11-28 CN CN201711212744.XA patent/CN109832397A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1876045A (en) * | 2003-01-08 | 2006-12-13 | 江苏康缘药业股份有限公司 | A Chinese medicinal composition, its preparation process and quality control method |
CN107372998A (en) * | 2017-08-23 | 2017-11-24 | 苏州唐基生物科技有限公司 | Sweet wormwood sugar with health-care efficacy and preparation method thereof |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110293704A (en) * | 2019-07-03 | 2019-10-01 | 蚌埠学院 | A kind of preparation method and its preforming device of Yunnan olive pressed candy |
CN112494590A (en) * | 2020-07-14 | 2021-03-16 | 蚌埠学院 | Traditional Chinese medicine liquor for preventing and treating new coronary pneumonia |
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Application publication date: 20190604 |
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