CN109832289A - A kind of composition pesticide containing Picarbutrazox and Metalaxyl-M - Google Patents
A kind of composition pesticide containing Picarbutrazox and Metalaxyl-M Download PDFInfo
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- CN109832289A CN109832289A CN201711225767.4A CN201711225767A CN109832289A CN 109832289 A CN109832289 A CN 109832289A CN 201711225767 A CN201711225767 A CN 201711225767A CN 109832289 A CN109832289 A CN 109832289A
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- picarbutrazox
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Abstract
The present invention relates to a kind of bactericidal composition comprising Picarbutrazox and Metalaxyl-M, the weight ratio of two kinds of effective component is 1-50:50-1, the weight percentage of effective component is 1-70%, preferably 5-50% in fungicide, remaining is the auxiliary agent and carrier allowed in pesticide.Composition of the invention has apparent synergistic effect, can reduce Pesticide use amount, environmentally friendly safety.
Description
Technical field
The invention belongs to technical field of pesticide, and in particular to be a kind of agriculture containing Picarbutrazox and Metalaxyl-M
Drug composition.
Background technique
Picarbutrazox belongs to carbamate fungicide, is a kind of active constituent with completely new binding mode,
It can be used for inhibiting Oomycete fungal disease, such as Bremia, pythium, Peronosporaceae, Pseudoperonospora, Phytophthora disease.Using
Crop includes melon vegetables, cereal, tomato, potato, lawn, romaine lettuce and other leafy vegetables.
。
Picarbutrazox chemical structure
Metalaxyl-M (metalaxyl-M) is the acid amide fungicides developed by Syngenta Co., Ltd, is the R isomery of common metalaxyl
Body is a kind of efficient systemic fungicide.To vegetables caused by downy mildew, phytophthora, pythium spp, fruit tree, tobacco, oil plant, cotton
The crop diseases such as colored and grain have preferable control efficiency.
Downy mildew of garpe (Plasmoparaviticola) is a kind of global disease, it have propagate fast, severe disease,
Crushing strong feature brings huge threat to high-quality pollution-free grape is produced.The general time underproduction 20% ~ 30%, seriously
Time may be up to 80% or more, to affect the yield and quality of grape, cause huge economic loss.It is different in production
Its disease resistance of grape variety has differences, and at present in addition to application cultivation step control, mainly uses chemical prevention, peasant generally adopts
With chemical controls such as Bordeaux mixture, Bravo, metalaxyl, Mancozebs.
Watermelon epidemic disease is one of the Major Diseases in watermelon production, belongs to silborne fungal diseases, watermelon epidemic disease can endanger leaf
Piece, vines and fruit form water soaking mode scab in sick portion, make blade and fruit rot, plant is withered, in rainy season and high temperature and humidity
Under the conditions of occur serious, often bring very big loss to watermelon production, cause the reduction of melon grower's economic well-being of workers and staff.The prevention and treatment of the disease at present
Mainly prevented and treated using the method for chemical agent.
In the prevention and treatment of watermelon epidemic disease and downy mildew of garpe, metalaxyl, dimethomorph and some protectiveness medicines are relied primarily on
Agent.These medicaments have produced different degrees of drug resistance because being used for a long time, and control efficiency reduces.The a large amount of of medicament make simultaneously
With pesticide residue is increased, food safety is endangered, has aggravated environmental pollution.Inventor is found by experiment that, not by the mechanism of action
Bactericide compounded, the active high, work of same Metalaxyl-M and Picarbutrazox prevention and treatment watermelon epidemic disease and downy mildew of garpe
With mechanism is unique, systemic activity is good, the lasting period is long, to crop safety the features such as, be the watermelon epidemic disease and oenin of significant
Mildew pesticide control.
Summary of the invention
The present invention is intended to provide a kind of effective component is the composition pesticide of Picarbutrazox and Metalaxyl-M, it is
The prevention and control of crop fungal disease provide a kind of more efficiently resistance management tool especially for crop downy mildew, epidemic disease.
To realize above-mentioned technical problem, the present invention adopts the following technical scheme:
A kind of composition pesticide containing Picarbutrazox and Metalaxyl-M, the Picarbutrazox and Metalaxyl-M
Weight ratio is 1-50:50-1, further preferably 1-20:20-1.
Further, the mass percent that active constituent accounts for composition in the composition pesticide is 1-70%, preferably 5-
50%。
The dosage form agriculturally allowed can be prepared by known methods into bactericidal composition of the invention, and preferable dosage form is
Wettable powder, dispersible oil-suspending agent, suspoemulsion, aqueous suspension agent, aqueous emulsion, microemulsion or water dispersible granules.
Composition pesticide of the invention has excellent preventive effect to downy mildew, the epidemic disease on the crops such as veterinary antibiotics, melon.
Compared with prior art, the invention has the benefit that
1, the preventive effect of corps diseases is greatly improved, quick-acting is obviously reinforced, and also there is certain extension in the lasting period, and dosage is more
It is low, reduce agricultural cost；2, toxicity is smaller, and residual quantity is less, is more conducive to environmental protection, improves the safety to crop
Property.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, present invention following specific embodiments
It is illustrated, but the present invention is limited to absolutely not these examples.The following is only the preferred embodiment of the present invention, is used only for explaining
The present invention, but cannot be therefore understands that being limitations on the scope of the patent of the present invention.It should be pointed out that it is all in spirit of the invention and
Made any modification, equivalent replacement or improvement etc., should all be included in the protection scope of the present invention within principle, therefore,
The scope of protection of the patent of the invention shall be subject to the appended claims.
One, example of formulations
The content of present invention is described further below with reference to embodiment, the effective component in example of formulations is weight after folding hundred
Amount.
One 25%Picarbutrazox Metalaxyl-M suspending agent of example of formulations
Weigh 15% Metalaxyl-M, 10%Picarbutrazox, sodium methylene bis-naphthalene sulfonate 5%, pull open powder 6%, glycerine 3%,
Aluminum magnesium silicate 0.2%, organosilicon 0.8%, water are supplemented to 100%.For above-mentioned raw materials through mixing, high speed shear disperses 30min, uses sand
Grinding machine is sanded to partial size D9025% Metalaxyl-M Picarbutrazox suspending agent is made after less than 10 microns.
Two 22%Picarbutrazox Metalaxyl-M missible oil of example of formulations
Weigh 14% Metalaxyl-M, 8%Picarbutrazox, N-Methyl pyrrolidone 10%, phenyl phenol polyoxyethyl ether 6%, alkane
Base phenolic resin polyoxyethyl ether 4%, vegetable oil are supplemented to 100%.Pesticide active ingredient, cosolvent, emulsifier, solvent are pressed
Ratio mixing, is mixed in modulation kettle, until completely dissolved, then remaining solvent is slowly added into, after being sufficiently stirred
Uniform oily phase is obtained, 22%Picarbutrazox Metalaxyl-M missible oil is made
Three 48%Picarbutrazox Metalaxyl-M water dispersible granules of example of formulations
20% Metalaxyl-M is weighed, 28%Picarbutrazox, spaonin powder 8%, pull open powder 7%, aluminium chloride 5%, White Carbon black are extremely
100%.Then plus the water of 15-20% pesticide activity component, auxiliary agent and filler are mixed in proportion, through air-flow crushing, through pinching
It closes, be granulated, is dry, sieving obtained 48%Picarbutrazox Metalaxyl-M water dispersible granules.
Oil-suspending agent can be dispersed in four 26%Picarbutrazox Metalaxyl-M of example of formulations
Weigh 16% Metalaxyl-M, 10%Picarbutrazox, 7%TERSPERSE2020,6% benzyl xylenol polyoxyethyl ether,
5% phenethyl phenol polyoxyethanyl polypropylene-base ether, 1% polyvinyl alcohol, 0.7% glycerol, 6% isopropanol, dimethylbenzene complement to 100%.On
Raw material is stated through mixing, high speed shear disperses 30min, is sanded with sand mill to partial size D9026% smart first frost is made after less than 10 microns
Clever Picarbutrazox suspending agent.
Five 34%Picarbutrazox Metalaxyl-M aqueous emulsion of example of formulations
Weigh 14% Metalaxyl-M, 20%Picarbutrazox, DMF6%, dimethylbenzene 25%, glycerol 3%, alkylaryl polyoxy second
Alkene polyethenoxy ether 15%, water is supplemented to 100%.Then above-mentioned raw materials use high shear emulsifying through mixing.Revolving speed 2500
Under the conditions of rev/min, 1 hour is persistently stirred i.e. up to fineness and various material dissolutions uniformly mixed obtained 34%
Picarbutrazox Metalaxyl-M aqueous emulsion.
Six 17%Picarbutrazox Metalaxyl-M microemulsion of example of formulations
Weigh 11% Metalaxyl-M, 6%Picarbutrazox, alkyl pyrrolidone 15%, phenyl phenol polyoxyethanyl ether phosphate
10%, alkylaryl polyoxyethylene poly-oxygen propylene aether 5%, ethylene glycol 3%, water are supplemented to 100%.By each group distribution ratio, will live
Property component be dissolved in solvent and cosolvent, surfactant is added, is uniformly mixed and oily phase is made.Water-soluble component and water are mixed
It closes and water phase is made, then during the oil phase is added to the aqueous phase or water phase is added in oily phase, it is stirring while adding, it is made 17%
Picarbutrazox Metalaxyl-M microemulsion.
Two, raw to survey embodiment
2.1, the indoor toxicity test of test example prevention and treatment downy mildew of garpe and field efficacy are tested
2.1.1 indoor toxicity test
Mixture is combined to understand Metalaxyl-M with Picarbutrazox to the definite virulence of downy mildew of garpe, the present invention for
Its proportion is screened.
Subjects: downy mildew of garpe
Test site: near the side street town of Yunnan Province, Songming County, Kunming
Test method: referring to " NY/T1156.3-2006 farm-chemical indoor determination test rule fungicide third portion: inhibition is yellow
Melon downy mildew germ tests plate blade method " it carries out.
Using in vitro leaf dish moisturizing method measurement Plasmopara viticola to the pesticide combination of Picarbutrazox and Metalaxyl-M
The sensibility of object.I.e. from the identical grape healthy leaves of acquisition leaf age, diameter is broken into punch after being dried with tap water flushing
For 1.2cm leaf dish, blade face is soaked in 1h in different disposal medical fluid upward, then blots the medical fluid in leaf dish with blotting paper, leaf
The back side is placed in bottom upward and is lined in the culture dish with identical medical fluid wetting blotting paper, and 10 μ L spore suspensions are inoculated in each leaf dish
Liquid (1 × 106A sporangium/mL), each culture dish puts 10 leaf dishes, is placed in (22 ± 2) DEG C, the artificial climate that humidity is 80%
In case, 16/8 photoperiod cultivated 7d, 3 repetitions of every processing.According to hypha growth condition in blank control ware, with calliper to measure bacterium
Fall diameter.Each bacterium colony uses crossing method vertical measurement, takes its average value, calculates inhibiting rate according to the following equation, and borrow
DPS Software of Data Statistics is helped to calculate each chemicals treatment to virulence regression equation, related coefficient, EC50And compounding co-toxicity coefficient.
Mycelial growth rate method, EC of the measurement different agents to bacterial strain are used indoors50, using co-toxicity coefficient calculation method, calculate
The co-toxicity coefficient (CTC) of mixture, determines the building performance of mixture, circular is as follows:
(EC is generally selected using certain in mixture-single dose as standard agent50Junior), it is calculated:
Single dose toxicity index=standard agent EC50/ certain single dose EC50×100
Theoretical toxicity index=A single dose toxicity index × A single dose proportion+B single dose in mixture toxicity index × B is mono-
Agent is in mixture proportion
Survey toxicity index=standard single dose EC50Value/mixture EC50Value × 100
Co-toxicity coefficient=survey toxicity index/theoretical toxicity index × 100
Co-toxicity coefficient classification: mixture has synergetic when CTC is greater than 120, is antagonism when CTC is less than 80, CTC is 80 ~ 120
Between be summation action.
Use embodiment 1-6Picarbutrazox (A) and Metalaxyl-M (B) with different ratio to downy mildew of garpe in table 1
Indoor biometrics experiment, as shown in Table 1, composition co-toxicity coefficient of the invention is all larger than 120, i.e., the present composition have compared with
Good synergetic, effect are better than single dose kind.
2.1.2, field control effectiveness test
Test process: the difference of each ingredient of this experimental evidence sets two medicaments dosage respectively, and dosing is that effective component is new
The quality of product (A) and Metalaxyl-M (B) and.Comparison medicament be respectively 20%Picarbutrazox can be dispersed oil-suspending agent and
10% Metalaxyl-M suspending agent and blank clean water experiment.
Test method: plot area is 10 plants of vines of open country.Random alignment, 4 repetitions.It is equal to entire plant when spray
It is even spraying, it is subject to the medical fluid that do not trickle.It will be washed with clear water sprayer 3 times before often changing a kind of processing, it is clear that equivalent is sprayed in blank control
Water;Later water and fertilizer management and farming operations are normally carried out.Investigation method: 10 current year pumpings of every cell random searching are newly climing, often
The tip investigates 20 leaves from top to bottom, records sick series respectively.State of an illness radix is investigated before first time is administered, after last 1 application
10d carries out last investigation, total investigation 3 times of entire test.Grade scale of the downy mildew of garpe on blade: 0 grade: disease-free spot;1
Grade: lesion area accounts for 5% or less entire leaf area;3 grades: lesion area accounts for the 6%~25% of entire leaf area;5 grades: scab face
Product accounts for the 26%~50% of entire leaf area;7 grades: lesion area accounts for the 51%~75% of entire leaf area;9 grades: lesion area accounts for whole
75% or more of a leaf area.
Drug effect calculation method
Test result see the table below:
Field efficacy the result shows that, as shown in Table 2, the present composition has obvious synergistic function, composition it is anti-
Excellent effect is controlled, control efficiency is better than single dose kind, has application value in agricultural application.
2.2, the indoor toxicity test of test example prevention and treatment watermelon epidemic disease and field efficacy are tested
2.2.1 indoor toxicity test
Mixture is combined to the definite virulence of watermelon epidemic disease in order to understand Metalaxyl-M with Picarbutrazox, and the present invention is for it
Proportion is screened.
The watermelon phytophthora colony edge for cultivating 3d in PDA culture medium with punch beats the bacteria cake for taking diameter 0.6cm, will
It is transferred in the PDA culture medium of the concentration containing different agents, and every ware connects a bacteria cake.Every kind of medicine sets 5 concentration processing, each gradient
Various concentration is set.Each processing sets 3 repetitions, sets no medicine processing separately as control.After cultivating 4d under 25 DEG C of constant temperature, using ten
Word interior extrapolation method measures colony diameter, calculates inhibiting rate, and finds out concentration EC in virulence regression equation and inhibition50.Specific calculating side
Method is as follows:
Using single dose a certain in mixture as standard agent, calculated:
Single dose toxicity index=standard agent EC50/ certain single dose EC50×100
Theoretical toxicity index=A single dose toxicity index × A single dose proportion+B single dose in mixture toxicity index × B is mono-
Agent is arranged in mixture institute's accounting
Survey toxicity index=standard single dose EC50Value/mixture EC50Value × 100
Co-toxicity coefficient=survey toxicity index/theoretical toxicity index × 100
Co-toxicity coefficient classification: mixture has synergetic when CTC is greater than 120, is antagonism when CTC is less than 80, CTC is 80 ~ 120
Between be summation action.
Use embodiment 1-6Picarbutrazox (A) and Metalaxyl-M (B) with different ratio to watermelon epidemic disease in table 3
Indoor biometrics experiment, as shown in Table 3, composition co-toxicity coefficient of the invention are all larger than 120, i.e. the present composition has preferable
Synergetic, effect is better than single dose kind.
2.2.2, field control effectiveness test
Test process: the difference of each ingredient of this experimental evidence sets two medicaments dosage respectively, and dosing is that effective component is new
The quality of product (A) and Metalaxyl-M (B) and.Comparison medicament be respectively 20%Picarbutrazox can be dispersed oil-suspending agent and
10% Metalaxyl-M suspending agent and blank clean water experiment.
Test method: 5 processing, 3 repetitions, 15 cells, each cell 30m are set altogether2, total 450m2, random between district's groups
Arrangement, using electronic knapsack sprayer dosage 60kg/667m2, uniformly it is sprayed on leave dual sides and vines.
Diseased plant grade scale: 0 grade: disease-free spot;L grades: individual blades have individual scabs;3 grades: 1/3 or less blades have scab
Or petiole has scab;There is scab in 5 grades: 1/3~1/2 blades, stems;There is scab with blade, stem for 7 grades: 1/2,1/2 with
There is scab in lower fruit;There is scab with blade, stem for 9 grades: 1/2, scab occurs in 1/2 or more fruit.
Test result see the table below:
Field efficacy the result shows that, as shown in Table 4, the present composition has obvious synergistic function, composition it is anti-
Excellent effect is controlled, control efficiency is better than single dose kind, has application value in agricultural application.
Claims (7)
1. a kind of composition pesticide, which is characterized in that active constituent includes Picarbutrazox and Metalaxyl-M.
2. composition pesticide according to claim 1, which is characterized in that the Picarbutrazox and Metalaxyl-M
Weight ratio is 1-50:50-1.
3. a kind of bactericidal composition containing Picarbutrazox and Metalaxyl-M, it is characterised in that: effective component is
The parts by weight of Picarbutrazox and Metalaxyl-M, Picarbutrazox and Metalaxyl-M in the composition are as follows: 1 ~ 70%,
The weight percent of Picarbutrazox and Metalaxyl-M weight summation in the composition is 5-50%.
4. composition pesticide described in any one of -2 claims according to claim 1, it is characterised in that: the pesticide combination
Object is aided with Pesticide formulation auxiliary element and is processed into any one dosage form for being suitble to agriculturally use.
5. composition pesticide according to claim 3, which is characterized in that the dosage form of the composition pesticide be missible oil, can
Wet powder, suspending agent, aqueous emulsion, microemulsion, water dispersible granules, dispersible oil-suspending agent, dispersible finish, dispersible
Agent, solvable pulvis, soluble granule, microcapsule suspending agent, suspoemulsion, liquor, it is any in finish in.
6. composition pesticide described in any one of -4 claims is used to prevent and kill off the purposes of corps diseases according to claim 1.
7. purposes according to claim 5, which is characterized in that the corps diseases are preferably downy mildew of garpe and watermelon
Epidemic disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711225767.4A CN109832289A (en) | 2017-11-29 | 2017-11-29 | A kind of composition pesticide containing Picarbutrazox and Metalaxyl-M |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711225767.4A CN109832289A (en) | 2017-11-29 | 2017-11-29 | A kind of composition pesticide containing Picarbutrazox and Metalaxyl-M |
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| CN109832289A true CN109832289A (en) | 2019-06-04 |
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| CN201711225767.4A Pending CN109832289A (en) | 2017-11-29 | 2017-11-29 | A kind of composition pesticide containing Picarbutrazox and Metalaxyl-M |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114342948A (en) * | 2022-01-05 | 2022-04-15 | 安徽丰乐农化有限责任公司 | Bactericidal composition and application thereof |
| CN116602311A (en) * | 2023-05-23 | 2023-08-18 | 青岛瀚生生物科技股份有限公司 | Bactericide for plant growth period and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110159110A1 (en) * | 2008-03-24 | 2011-06-30 | Nippon Soda Co., Ltd. | Plant disease control agent |
-
2017
- 2017-11-29 CN CN201711225767.4A patent/CN109832289A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110159110A1 (en) * | 2008-03-24 | 2011-06-30 | Nippon Soda Co., Ltd. | Plant disease control agent |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114342948A (en) * | 2022-01-05 | 2022-04-15 | 安徽丰乐农化有限责任公司 | Bactericidal composition and application thereof |
| CN116602311A (en) * | 2023-05-23 | 2023-08-18 | 青岛瀚生生物科技股份有限公司 | Bactericide for plant growth period and application thereof |
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