CN1098306A

CN1098306A - A kind of plaster sticking on umbilical region for the treatment of constipation and preparation method thereof

Info

Publication number: CN1098306A
Application number: CN 93115719
Authority: CN
Inventors: 齐英天; 商伟; 齐鸣
Original assignee: ANSHAN CITY CENTRAL HOSPITAL
Current assignee: ANSHAN CITY CENTRAL HOSPITAL
Priority date: 1993-08-03
Filing date: 1993-08-03
Publication date: 1995-02-08

Abstract

The present invention relates to a kind of plaster sticking on umbilical region for the treatment of constipation and preparation method thereof.This plaster sticking on umbilical region mainly adopts raw materials such as Radix Et Rhizoma Rhei, Natrii Sulfas, Borneolum Syntheticum and Mel, and each component sum is 1～1.2 with the ratio of the parts by weight of Mel, and wherein the Radix Et Rhizoma Rhei consumption is 30 to 80 parts (weight); The Natrii Sulfas consumption is 10 to 20 parts (weight); The Borneolum Syntheticum consumption is 5 to 10 parts (weight), by select materials, dry, pulverize, grind, and Natrii Sulfas and Mel are dissolved and refines the processing postcooling, steps such as reinforced mixing are made unguentum, and repaste is finished product in patch, and it is easy to use, effect is obvious and lasting, does not have any untoward reaction.

Description

A kind of plaster sticking on umbilical region for the treatment of constipation and preparation method thereof

The present invention relates to a kind of Chinese medicine plaster that is used for the treatment of constipation, belong to the umbilical external application preparation, be applicable to various chronic constipations, especially habitual constipation, functional constipation.

At present, the pharmaceutical preparation that is used for the treatment of constipation is a lot, as Radix Et Rhizoma Rhei clearing stomach ball, Fructus Cannabis Bolus, Folium Sennae, mannitol, magnesium sulfate, glycerin etc.The treatment constipation medicament that the traditional Chinese medical science is traditional has DACHENGQI TANG, Xiao Chengqi Tang, transfer stomach CHENGQI TANG etc., wherein DACHENGQI TANG is one of important prescription in the Ancient Chinese generation treatise on Febrile Diseases of famous medicine scholar Zhang Zhongjing, merit is arrogated to oneself logical stomach knot, rescue stomach-Yin, hold along row under the gastric qi, the eliminating stagnation relieving constipation, it is Radix Et Rhizoma Rhei, Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus, Natrii Sulfas that its prescription is formed.Have purging heat to relax the bowels, cleanse the intestines and stomach, attack effect, be used widely clinically by six internal organs.Yet the above medicine all is by oral or rectal administration, thereby has certain shortcoming, because medicine to the zest effect of intestinal wall, increases intestinal peristalsis promoting, therapeutic process is often with abdominal discomfort or pain symptom as oral administration.Rectally has the zest effect to anus, and prolonged application causes that easily anus is of flaccid muscles.Described medicine is preferable to acute constipation effect, and often only removes symptom for the moment for chronic, habitual constipation, needs long-term prescription, and the dosage of medication also prolongs and increases to some extent along with the medication phase.

In view of this, seek and a kind ofly both can treat chronic, habitual constipation, the application preparation that can overcome oral and rectally shortcoming again is a very important task.

The purpose of this invention is to provide the treatment constipation plaster that a kind of umbilical external application is used, close at last and thinnest part, help the infiltration and the absorption of medicine because umbilical part is a stomach wall.Umbilical part is again the SHENQUE acupoint in the acupuncture-moxibustion acupuncture point, is one of most important acupuncture point of human body, is total pivot of meridians, pasting can stimulate and regulate collaterals of human behind the medicine and make that it is unobstructed, coordinate also scalable abdominal viscera nerve, organ function is strengthened, stool is discharged smoothly, reach the relieving constipation purpose.

For achieving the above object, the technical measures that the present invention takes are for adopting following raw materials according prescription, proportioning by weight: 30～80 parts of Radix Et Rhizoma Rhei, 10～20 parts in Natrii Sulfas, 5～10 parts of Borneolum Syntheticums.Wherein the effect of Borneolum Syntheticum is the absorption that promotes other composition, so the quasi-drugs of available equivalent such as menthol or Camphora replace.

Above-mentioned prescription can reach the purpose of treatment chronic constipation, but for improving curative effect, can also add the following raw materials according component, proportioning by weight: 0.5～5 part of Radix Angelicae Sinensis, 0.5～5 part of Radix Scrophulariae, 0.5～5 part of interior Herba Cistanches, 0.5～3 part in the Radix Rehmanniae, 0.5～3 part on Flos Carthami, 0.5～3 part of Radix Codonopsis, 0.5～3 part of Cortex Magnoliae Officinalis.No matter be to plant the composition prescription by first three, still by adding next seven kinds of composition prescriptions, 1～1.2 times the Mel that all will add each component summation parts by weight can.

The preparation method of plaster sticking on umbilical region of the present invention is by material component recited above and proportioning prescription, again by following processing step preparation: the Radix Et Rhizoma Rhei during (1) will fill a prescription, Radix Angelicae Sinensis, Radix Scrophulariae, Herba Cistanches, the Radix Rehmanniae, Cortex Magnoliae Officinalis, Radix Codonopsis, Flos Carthami are respectively after under 70～80 ℃ dry 4～5 hours, cross sieve No. six, Borneolum Syntheticum porphyrize in will filling a prescription is again crossed sieve No. five; Natrii Sulfas in will filling a prescription then adds the water of itself parts by weight 1/3rd, is heated to and boils, and makes it dissolving, and Mel is added heat refining to 116～118 ℃.(2) get each component in the ratio branch in the above-mentioned prescription, Natrii Sulfas solution is added in the hot Mel while hot, be chilled to room temperature, add various material components again, stirring and evenly mixing is made unguentum.(3) paste 2～4g in the dimetric patch of 2.5cm is finished product.

The advantage that the present invention is used for the treatment of the plaster of constipation is: owing to be the umbilical external application medication, route of administration is convenient, not dirty linen; Owing to can make stool relatively relax discharge, so do not have the abdominal discomfort symptom and to the anus zest.Medicine is to absorb from umbilical part, owing to the stimulation to collaterals of human and abdominal viscera nerve, can improve gastrointestinal function better, makes lasting medicine.

The treatment constipation with the using method of plaster sticking on umbilical region is: plaster sticking on umbilical region pasted into omphalos portion, and available 2～4 days of every subsides, to the in addition hot compress of subsides medicine position, effect is better, hot compress 2～3 times on the one, each 3～5 minutes after the medication.

The result of use criterion is:

Cure: drug withdrawal after pasting with plaster one subsides or number still can keep free movement of the bowels two months.

Produce effects: through bowel sounds active promptly being arranged with plaster within 1 day, the sense of abdominal part feeling of distension and oppression disappears, and stool is discharged smoothly.

Effectively: through alleviating with the swollen full feeling of distension and oppression sense of abdominal part in the plaster 1 to 3 day or disappearing conscious bowel sounds active, continuous exhaust pneumatic wallop, and defecation.

Invalid: through using plaster more than 3 days, the abdominal part idol is felt has aerofluxus, no defecation by chance by borborygmus.

The invention will be further described below by embodiment and clinical observation result:

Embodiment 1

Prepare the plaster sticking on umbilical region that the treatment constipation of 1.13kg is used by following prescription and proportioning: get Radix Et Rhizoma Rhei 400g, Natrii Sulfas 100g, Borneolum Syntheticum 50g, Mel 550g.At first with preferred Radix Et Rhizoma Rhei in 75～80 ℃ dry 4 hours down, pulverize, cross sieve No. six, again with the Borneolum Syntheticum porphyrize, cross sieve No. five, in Natrii Sulfas, add 30 ml waters then, be heated to and boil, make it dissolving, and Mel added heat refining to 116～118 ℃.Natrii Sulfas solution is added in the hot Mel while hot, is chilled to room temperature, add Radix Et Rhizoma Rhei and Borneolum Syntheticum smalls again, stirring and evenly mixing, make unguentum after, unction 3g on 2.5cm square medical rubber patch cloth is finished product.

Embodiment 2

Prepare the plaster sticking on umbilical region that the treatment constipation of 1.47kg is used by following prescription and proportioning: Radix Et Rhizoma Rhei 400g, Natrii Sulfas 100g, Borneolum Syntheticum 50g, Radix Angelicae Sinensis 30g, Radix Scrophulariae 30g, Herba Cistanches 30g, Flos Carthami 20g, Cortex Magnoliae Officinalis 20g, Radix Rehmanniae 20g, Radix Codonopsis 20g, Mel 720g.At first that the Radix Et Rhizoma Rhei in the raw material, Radix Angelicae Sinensis, Radix Scrophulariae, Herba Cistanches, the Radix Rehmanniae, Cortex Magnoliae Officinalis, Flos Carthami, Radix Codonopsis is preferred respectively, in 75～80 ℃ dry 4 hours down, pulverize, cross sieve No. six, again with the Borneolum Syntheticum porphyrize, cross sieve No. five; In Natrii Sulfas, add 30 ml waters then, be heated to and boil, make it dissolving, and Mel is added heat refining to 116～118 ℃.Natrii Sulfas solution is added in the hot Mel while hot, be chilled to room temperature, add Radix Et Rhizoma Rhei, Radix Angelicae Sinensis, Radix Scrophulariae, Herba Cistanches, Flos Carthami, Cortex Magnoliae Officinalis, the Radix Rehmanniae, Radix Codonopsis, Borneolum Syntheticum raw material smalls again, stirring and evenly mixing, make behind the unguentum unction 3g on 2.5cm square medical rubber patch cloth, be finished product.

Treatment constipation prepared among embodiment 1 and the embodiment 2 is observed its effect with plaster sticking on umbilical region after clinical use be:

The plaster sticking on umbilical region that the prescription of Application Example 1 makes is 88% through 130 routine chronic functional constipations, habitual constipation patient's use total effective rate, wherein cures 28 examples, produce effects 66 examples, effective 21 examples, invalid 15 examples.

The plaster sticking on umbilical region that the prescription of Application Example 2 makes, the over thousands of routine chronic functional constipation of nineteen ninety to 1993 year by statistics, the patient of habitual constipation, male 1.5 years old to 87 years old, women 1 years old to 91 years old uses this plaster sticking on umbilical region, cures 260 examples, produce effects 526 examples, effective 201 examples, invalid 18 examples, total effective rate is 98.2%, use plaster sticking on umbilical region except that accidental rubber plaster allergy sufferers, do not have other untoward reaction.

Claims

1, a kind of plaster sticking on umbilical region that is used for the treatment of constipation, it is characterized in that mainly adopting Radix Et Rhizoma Rhei, Natrii Sulfas, Borneolum Syntheticum and Mel is raw material, and the each component sum is 1～1.2 with the ratio of the parts by weight of Mel, and wherein Radix Et Rhizoma Rhei is 30～80 parts, 10～20 parts in Natrii Sulfas, 5～10 parts of Borneolum Syntheticums.

2, plaster sticking on umbilical region as claimed in claim 1 is characterized in that Borneolum Syntheticum wherein can replace with the menthol or the Camphora of equivalent.

3, plaster sticking on umbilical region as claimed in claim 1 or 2, it is characterized in that it also can add the following raw materials according component, added each component ratio of weight and number is: 0.5～5 part of Radix Angelicae Sinensis, 0.5～5 part of Radix Scrophulariae, 0.5～5 part of interior Herba Cistanches, 0.5～3 part on Flos Carthami, 0.5～3 part in the Radix Rehmanniae, 0.5～3 part of Radix Codonopsis, 0.5～3 part of Cortex Magnoliae Officinalis.

4, a kind of preparation method that is used for the treatment of the plaster sticking on umbilical region of constipation, it is characterized in that by above-mentioned prescription and proportioning prescription: 30～80 parts of Radix Et Rhizoma Rhei, 10～20 parts in Natrii Sulfas, 5～10 parts of Borneolum Syntheticums, 0.5～5 part of Radix Angelicae Sinensis, 0.5～5 part of Radix Scrophulariae, 0.5～3 part on Flos Carthami, 0.5～3 part in the Radix Rehmanniae, 0.5～3 part of Radix Codonopsis, 0.5～3 part of Cortex Magnoliae Officinalis, 0.5～3 part of Herba Cistanches, the each component sum is 1～1.2 with the ratio of the parts by weight of Mel;

Its processing step is:

(1) with the Radix Et Rhizoma Rhei in the above-mentioned prescription, Radix Angelicae Sinensis, Radix Scrophulariae, Herba Cistanches, the Radix Rehmanniae, Cortex Magnoliae Officinalis, Radix Codonopsis, Flos Carthami pulverize separately, cross sieve No. six, again with the Borneolum Syntheticum porphyrize, cross sieve No. five, the water that in Natrii Sulfas, adds itself parts by weight 1/3rd, be heated to and boil, make it dissolving, Mel is added heat refining to 116～118 ℃;

(2) get each component in the ratio branch in the above-mentioned prescription, Natrii Sulfas solution is added in the hot Mel while hot, be chilled to room temperature, add various material components again, stirring and evenly mixing is made unguentum;

(3) 2～4g unguentum is coated in the dimetric patch of 2.5cm, is finished product.