CN109806358A - A kind of ten taste reinforcings spleen to promote digestion dissipate and its preparation method and application - Google Patents
A kind of ten taste reinforcings spleen to promote digestion dissipate and its preparation method and application Download PDFInfo
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- CN109806358A CN109806358A CN201811457029.7A CN201811457029A CN109806358A CN 109806358 A CN109806358 A CN 109806358A CN 201811457029 A CN201811457029 A CN 201811457029A CN 109806358 A CN109806358 A CN 109806358A
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Abstract
The present invention provides a kind of ten taste reinforcings spleen to promote digestion to dissipate, it is prepared by the bulk pharmaceutical chemicals of following weight proportion: 50~75 parts of ginseng, 84~126 parts of Poria cocos, 84~126 parts of stir-baked RHIZOMA ATRACTYLDIS MACROCEPHALAE in bran, 84~126 parts of dried orange peel, net 84~126 parts of hawthorn, 84~126 parts of Fructus Hordei Germinatus, 84~126 parts of Endothelium Corneum Gigeriae Galli (parched), 56~84 parts of cardamom, fry 168~252 parts of Semen Lablab Album, 56~84 parts of honey-fried RADIX GLYCYRRHIZAE.The present invention further discloses the help digestion scattered preparation method and purposes.Ten taste provided by the invention, which helps digestion, dissipates energy invigorating the spleen qi-regulating, digesting and appetizing, can be used for treating functional dyspepsia FD, Functional Gastrointestinal Disease, has stronger practical application value.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of ten taste reinforcings spleen to promote digestion dissipate and its preparation method and application.
Background technique
As the improvement of people's living standards, and the accelerating rhythm of life, overeating and the irregular phenomenon of diet
More and more, this causes greatly to injure to our stomach.The disease incidence of the diseases such as indigestion, gastrointestinal disease is higher and higher,
Seriously affect our quality of life.
Clinical application at present is many in the drug of promotion digestion and treatment gastrointestinal disease, but these drugs are mainly Western medicine, west
The toxic side effect of medicine is larger and easy tolerance.Therefore, curative for effect, Small side effects Chinese medicine compositions are needed to treat, are improved
The quality of life of patient.And currently, there is not yet the relevant report scattered about ten taste reinforcings spleen to promote digestion of the invention.
Summary of the invention
Dissipated the purpose of the present invention is to provide a kind of ten taste reinforcings spleen to promote digestion and its preparation method and application.
The present invention provides a kind of Traditional Chinese medicine for reinforcing spleen to promote digestion compositions, it is prepared by the bulk pharmaceutical chemicals of following weight proportion
It forms: 50~75 parts of ginseng, 84~126 parts of Poria cocos, 84~126 parts of stir-baked RHIZOMA ATRACTYLDIS MACROCEPHALAE in bran, 84~126 parts of dried orange peel, net hawthorn 84~
126 parts, 84~126 parts of Fructus Hordei Germinatus, 84~126 parts of Endothelium Corneum Gigeriae Galli (parched), 56~84 parts of cardamom, 168~252 parts of Semen Lablab Album of stir-fry is close sweet
56~84 parts of grass.
Further, aforementioned Chinese medicine composition is prepared by the bulk pharmaceutical chemicals of following weight proportion: 63 parts of ginseng, Fu
105 parts of Siberian cocklebur, 105 parts of stir-baked RHIZOMA ATRACTYLDIS MACROCEPHALAE in bran, 105 parts of dried orange peel, 105 parts of net hawthorn, 105 parts of Fructus Hordei Germinatus, 105 parts of Endothelium Corneum Gigeriae Galli (parched), cardamom 70
Part, fry 210 parts of Semen Lablab Album, 70 parts of honey-fried RADIX GLYCYRRHIZAE.
Further, aforementioned Chinese medicine composition is that by the medicinal powder of bulk pharmaceutical chemicals of the weight proportion, the water of bulk pharmaceutical chemicals or have
Solvent extract is active constituent, in addition the preparation that pharmaceutically acceptable auxiliary material is prepared.
Further, the preparation is oral preparation.
Further, the oral preparation is decoction, electuary, pill, tablet, powder, granule, sublimed preparation or oral solution.
The present invention also provides a kind of methods for preparing aforementioned Chinese medicine composition, it includes the following steps:
A, the raw material of each weight proportion is weighed；
B, raw material directly beaten to powder, or after adding water or organic solvent to extract, pharmaceutically acceptable auxiliary material or auxiliary is added
Property ingredient is prepared.
The present invention also provides purposes of the aforementioned Chinese medicine composition in preparation invigorating the spleen, the drug for helping digestion, whetting the appetite.
Further, the drug is the drug for treating post-prandial fullness, anorexia, belch.
Further, the drug is the drug for treating nausea and vomiting, epigastric pain.
Further, the drug is the drug for treating early satiety.
Ten tastes of the invention help digestion dissipate be by ginseng, Poria cocos, stir-baked RHIZOMA ATRACTYLDIS MACROCEPHALAE in bran, dried orange peel, net hawthorn, Fructus Hordei Germinatus, Endothelium Corneum Gigeriae Galli (parched),
Cardamom fries Semen Lablab Album, ten herbal medicine of honey-fried RADIX GLYCYRRHIZAE composition.
How weakness of the spleen and the stomach functional gastrointestinal patient is, QI stagnating in middle-JIAO, and side's ginseng sweet temperature QI invigorating, strengthening spleen and nourishing stomach, bran is fried white
Art sweetness and bitterness and warm, invigorating the spleen to dry, mutually assist air making-up and spleen enlivening with ginseng；Poria cocos is sweet light, invigorating the spleen excreting dampness, fries Semen Lablab Album invigorating the spleen for eliminating dampness, white
Art, Poria cocos, the dehumidifying of Semen Lablab Album phase 5 help fortune；Net hawthorn, Fructus Hordei Germinatus help digestion stomach function regulating, and not only disappeared the product stopped, but also to close Endothelium Corneum Gigeriae Galli (parched) total
Gather the function of stomach invigorating appetizing；Dried orange peel, cardamom invigorating the spleen for eliminating dampness and with promoting the circulation of qi, promoting of being amusing and remove abdominal fullness and distention；Assistant is with honey-fried RADIX GLYCYRRHIZAE tonifying spleen
QI invigorating, and coordinating the drug actions of a prescription.
Clinical research shows that ten taste provided by the invention helps digestion and dissipates energy invigorating the spleen qi-regulating, digesting and appetizing, can be used for treating function
Energy property indigestion, Functional Gastrointestinal Disease, have stronger practical application value.
Obviously, above content according to the present invention, according to the ordinary technical knowledge and strong hand of relevant art
Section, under the premise of not departing from above-mentioned basic fundamental thought of the invention, can also make the modifications of other diversified forms, replacement or
Change.
The specific embodiment of form by the following examples remakes above content of the invention further detailed
Explanation.But the range that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to example below.It is all above-mentioned interior based on the present invention
Hold realized technology to all belong to the scope of the present invention.
Specific embodiment
Ten tastes of the invention of embodiment 1 help digestion scattered preparation
(1) raw material: ginseng 63g, Poria cocos 105g, stir-baked RHIZOMA ATRACTYLDIS MACROCEPHALAE in bran 105g, dried orange peel 105g, net hawthorn 105g, Fructus Hordei Germinatus
105g, Endothelium Corneum Gigeriae Galli (parched) 105g, cardamom 70g fry Semen Lablab Album 210g, honey-fried RADIX GLYCYRRHIZAE 70g.
(2) bulk pharmaceutical chemicals preparation method: are weighed by above-mentioned weight proportion；Full medicine forced air drying 5 hours under 70 degree, crush,
It sieves with 100 mesh sieve, packing to the every packet of 10g.
Ten tastes of the invention of embodiment 2 help digestion scattered preparation
(1) raw material: ginseng 75g, Poria cocos 84g, stir-baked RHIZOMA ATRACTYLDIS MACROCEPHALAE in bran 84g, dried orange peel 84g, net hawthorn 84g, Fructus Hordei Germinatus 84g fry chicken
Interior gold 84g, cardamom 84g fry Semen Lablab Album 168g, honey-fried RADIX GLYCYRRHIZAE 84g.
(2) bulk pharmaceutical chemicals preparation method: are weighed by above-mentioned weight proportion；Full medicine forced air drying 5 hours under 70 degree, crush,
It sieves with 100 mesh sieve, packing to the every packet of 10g.
Ten tastes of the invention of embodiment 3 help digestion scattered preparation
(1) raw material: ginseng 50g, Poria cocos 126g, stir-baked RHIZOMA ATRACTYLDIS MACROCEPHALAE in bran 126g, dried orange peel 126g, net hawthorn 126g, Fructus Hordei Germinatus
126g, Endothelium Corneum Gigeriae Galli (parched) 126g, cardamom 56g fry Semen Lablab Album 252g, honey-fried RADIX GLYCYRRHIZAE 56g.
(2) bulk pharmaceutical chemicals preparation method: are weighed by above-mentioned weight proportion；Full medicine forced air drying 5 hours under 70 degree, crush,
It sieves with 100 mesh sieve, packing to the every packet of 10g.
Beneficial effects of the present invention are proved below by way of specific clinical test.
Ten tastes of the invention of test example 1 help digestion scattered clinical efficacy
1, clinical data
Observation case totally 45, the age is 18~80 years old.
1.1 patients are included in standard
It is formulated according to document Rome Ⅲ criteria:
1. patient symptom shows as post-prandial fullness, anorexia, belch, nausea and vomiting, epigastric pain, early satiety etc.；
2. the age 18~80 years old；
3. showing do not occur the illnesss such as esophagitis, gastric and duodenal ulcer, tumour, erosion through gastrocopy.
1.2 patient's exclusion criterias
1. the age was less than 18 years old or was greater than 80 years old；
2. merging serious cardiopulmonary hepatic and kidney function obstacle person；
3. drug allergy, nursing period and pregnancy women and being reluctant partner；
4. doubtful, there are malignant change persons.
2, therapeutic scheme
2.1 experimental groups: giving the drug of the preparation of the embodiment of the present invention 1, assesses curative effect after treating 1 course for the treatment of.
2.2 specific medications are as follows: this medicine daily 3 times, 1 time 1 bag, boiled water is taken after mixing it with water, each taking drug weight
Amount is equivalent to 10 grams of crude drugs, and 4 weeks are 1 course for the treatment of.
3, observation of curative effect
3.1 evaluation index
The symptom score: " function promulgated according to Chinese Association of Chinese and Western Medicine disease of digestive system Professional Committee in 2010
Can property dyspeptic combination of Chinese tradiational and Western medicine diagnosis and treatment National Consensus (2010) " in FD Syndrome Scale quantitative criteria formulate, including it is postprandial
Glutted discomfort, early satiety, stomach receive reduction, belch, pharyngeal sense of obstruction, irritable, remember 0 respectively by 0 grade, I grades, II grades, III level,
3,5,7 points, score is higher, shows that symptom is more serious.
FDQOL scoring: referring to Chinese edition functional dyspepsia FD Development of Quality of Life Scale (functional digestive
Disorder quality of life questionnaire, FDQOL) evaluation quality of life, score is higher, shows to live
Quality is higher.
3.2 criterions of therapeutical effect:
Be clearly better (effective): after treating 1 course for the treatment of, the digestion such as patient's early satiety, upper abdomen pain, stomach burning sensation are not
Good illness disappears or completely disappears substantially, and bad digestion time is accumulative less than 30min weekly；
It improves (effective): after treating 1 course for the treatment of, patient's items digestive system illness, such as early satiety, upper abdomen pain, stomach
It is bright etc. to significantly improve, and the indigestion cumulative time is less than weekly 1h；
It is invalid: after treating 1 course for the treatment of, with treatment before comparison, people digest's system condition not be improved significantly.
Total effective rate=(effective+effectively)/total number of cases × 100%.
3.3 treatment results
1 symptom integral of table and FDQOL scoring are compared before and after treatment
Ten tastes of the invention of table 2 help digestion scattered treatment results
| Group | It is clearly better | It improves | In vain | It is efficient |
| Experimental group (45 people) | 26 | 18 | 1 | 97.78% |
Experiment conclusion: after ten tastes help digestion and dissipate treatment, people digest road symptom is obviously improved, and quality of life significantly improves,
Pretherapy and post-treatment comparing difference has statistical significance.Ten tastes, which help digestion, dissipates treatment functional dyspepsia FD effective percentage up to 97.78%；
Obvious effective rate is up to 57.8%.Ten tastes of the invention, which help digestion, to be dissipated for the curative for effect of gastrointestinal disease, and clinical application is worth.
4, typical case
4.1 classical cases 1
Patient Zhang, women, 71 years old, because " upper abdomen secret anguish 10+ repeatedly " is admitted to hospital, main clinical manifestation: upper abdomen
Pain, abdominal distension aggravate after feed, and no Nausea and vomiting, no sour regurgitation is heartburn, no belch, hiccup, poor, difficulty falling asleep of sleeping, and appetite is suitable
Amount decline, pink tongue, greasy and thin fur, veins string.Physical examination: mild tenderness under xiphoid-process, no rebound tenderness, muscle tonue.Gastroscope prompt: stomach is more
Send out polyp.The treatment of patient's the past Multiple Hospitalization, after giving the acid suppressions such as Omeprazole shield stomach treatment, patient's upper abdomen pain is without bright
It is aobvious to alleviate.Give ten tastes after being admitted to hospital to help digestion raw edge clothes, after treatment 2 weeks, patient tells upper abdomen pain, hence it is evident that alleviates, appetite is good
Turn, continues to take 2 weeks after discharge, Effect of follow-up visit by telephone, patient's appetite improves in right amount, without abdominal pain, abdominal distension, no Nausea and vomiting after feed
Etc. discomforts, conditions of patients be clearly better.
In conclusion ten taste provided by the invention, which helps digestion, dissipates energy invigorating the spleen qi-regulating, digesting and appetizing, can be used for treating functionality
Indigestion, Functional Gastrointestinal Disease have stronger practical application value.
Claims (10)
1. a kind of Traditional Chinese medicine for reinforcing spleen to promote digestion composition, it is characterised in that: it is prepared by the bulk pharmaceutical chemicals of following weight proportion:
50~75 parts of ginseng, 84~126 parts of Poria cocos, 84~126 parts of stir-baked RHIZOMA ATRACTYLDIS MACROCEPHALAE in bran, 84~126 parts of dried orange peel, 84~126 parts of net hawthorn is raw
84~126 parts of malt, 84~126 parts of Endothelium Corneum Gigeriae Galli (parched), 56~84 parts of cardamom, 168~252 parts of Semen Lablab Album are fried, honey-fried RADIX GLYCYRRHIZAE 56~84
Part.
2. according to Chinese medicine composition described in claim 1, it is characterised in that: it be by following weight proportion bulk pharmaceutical chemicals preparation and
At: 63 parts of ginseng, 105 parts of Poria cocos, 105 parts of stir-baked RHIZOMA ATRACTYLDIS MACROCEPHALAE in bran, 105 parts of dried orange peel, 105 parts of net hawthorn, is fried in chicken by 105 parts of Fructus Hordei Germinatus
105 parts of gold, fries 210 parts of Semen Lablab Album, 70 parts of honey-fried RADIX GLYCYRRHIZAE by 70 parts of cardamom.
3. Chinese medicine composition according to claim 1 or 2, it is characterised in that: it is by the bulk pharmaceutical chemicals of the weight proportion
Medicinal powder, bulk pharmaceutical chemicals water or extractive with organic solvent be active constituent, in addition what pharmaceutically acceptable auxiliary material was prepared
Preparation.
4. Chinese medicine composition according to claim 3, it is characterised in that: the preparation is oral preparation.
5. Chinese medicine composition according to claim 4, it is characterised in that: the oral preparation be decoction, electuary, pill,
Tablet, powder, granule, sublimed preparation or oral solution.
6. a kind of method for preparing Chinese medicine composition described in Claims 1 to 5 any one, it is characterised in that: it includes as follows
Step:
A, the raw material of each weight proportion is weighed；
B, raw material directly beaten to powder, or after adding water or organic solvent to extract, be added pharmaceutically acceptable auxiliary material or it is complementary at
Divide and is prepared.
7. purposes of the Chinese medicine composition described in Claims 1 to 5 any one in preparation invigorating the spleen, the drug for helping digestion, whetting the appetite.
8. purposes according to claim 7, it is characterised in that: the drug is treatment post-prandial fullness, anorexia, belch
Drug.
9. purposes according to claim 7, it is characterised in that: the drug is the drug for treating nausea and vomiting, epigastric pain.
10. purposes according to claim 7, it is characterised in that: the drug is the drug for treating early satiety.
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| CN201811457029.7A CN109806358A (en) | 2018-11-30 | 2018-11-30 | A kind of ten taste reinforcings spleen to promote digestion dissipate and its preparation method and application |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105521094A (en) * | 2014-09-29 | 2016-04-27 | 黄乔智 | Decoction for treating infantile malnutrition |
| CN108567936A (en) * | 2018-07-10 | 2018-09-25 | 江西皓宇生物科技有限公司 | Appetite-stimulating and indigestion-relieving Chinese medicine composition, preparation and preparation method thereof |
-
2018
- 2018-11-30 CN CN201811457029.7A patent/CN109806358A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105521094A (en) * | 2014-09-29 | 2016-04-27 | 黄乔智 | Decoction for treating infantile malnutrition |
| CN108567936A (en) * | 2018-07-10 | 2018-09-25 | 江西皓宇生物科技有限公司 | Appetite-stimulating and indigestion-relieving Chinese medicine composition, preparation and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 程青: "中西医结合治疗腹部手术病人术后厌食 ", 《实用临床医学》 * |
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Application publication date: 20190528 |