CN109806183A - A kind of preparation method and photoprotection application of the Essence containing beta glucan - Google Patents
A kind of preparation method and photoprotection application of the Essence containing beta glucan Download PDFInfo
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- CN109806183A CN109806183A CN201910263920.5A CN201910263920A CN109806183A CN 109806183 A CN109806183 A CN 109806183A CN 201910263920 A CN201910263920 A CN 201910263920A CN 109806183 A CN109806183 A CN 109806183A
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- beta glucan
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Abstract
The present invention provides a kind of preparation method containing the Essence for photoprotection, the preparation method includes the following steps: that (1) is described and prepares the aqueous solution that solute is hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol；(2) beta glucan, purple perilla alcohol extract and lucid asparagus water extract are added into step (1) obtained aqueous solution, stir evenly to get.The present invention is under light irradiation, and with technical effect that is anti-oxidant, removing free radical, being used for a long time has sun-proof, whitening function.
Description
Technical field
The present invention relates to skin protection technical fields, and in particular to a kind of preparation method of the Essence containing beta glucan and
The application of skin photoprotection.
Background technique
In daily routines, the ultraviolet radiation of the sun can enable skin prematurely aging.Particularly, under light irradiation, skin
A large amount of free radicals can be generated, the health of skin is unfavorable for.Long period is exposed under burning sun, and strong light loss can be generated to skin
Wound, the expansion of illuminated position dermal vascular, skin may occur in which the symptoms such as redness, bubble, permanent irradiation skin there is also erythema,
Inflammation, skin aging, serious person can cause cutaneum carcinoma.
Currently, general sunscreen products, especially sun-proof Essence, are typically only capable to play a degree of isolation effect, and
Injury of the light irradiation for skin cannot be fundamentally reduced, the generation of free radical is especially reduced.
Therefore, this field needs a kind of skin-protection product with good photoprotection.
Summary of the invention
In view of the shortcomings of the prior art, the purpose of the present invention is to provide a kind of systems containing the Essence for photoprotection
Preparation Method, the preparation method include the following steps:
(1) described to prepare the aqueous solution that solute is hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol；
(2) beta glucan, purple perilla alcohol extract and lucid asparagus water extract are added into step (1) obtained aqueous solution, stirring is equal
It is even to get；
Wherein, the weight ratio of beta glucan, purple perilla alcohol extract and lucid asparagus water extract is 5:1~2:1；
The hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol weight ratio be 4:2:2:1:1；The β-
The weight ratio of glucan and hyaluronic acid is 1:7；
The beta glucan is 200,000 dalton by the macromolecular beta glucan and molecular weight that molecular weight is 1,200,000 dalton
Small molecule beta glucan according to weight ratio 1:0.618 form；
The acquisition methods of the purple perilla alcohol extract are as follows:
Purple perilla is cleaned, is dry, dry grain is then comminuted into, the second of 80%v/v is placed in the ratio of solid and liquid weight ratio 1:5
It is carried out refluxing extraction 1.5 hours in alcohol, filtering discards solid formation, and liquid portion is taken to be rotated, and takes gained solid phase powder after revolving
End to get；
The acquisition methods of the lucid asparagus water body object are as follows:
Fresh lucid asparagus is cleaned, its stem is taken, after homogenate, is placed in water back in the ratio of solid and liquid weight ratio 1:2
Stream extract 2 hours, filtering discard solid formation, take liquid portion to be rotated, take revolving after gained solid phase powder to get.
Preferably, the weight of solute in the aqueous solution of hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol is stated
Score is 8~16%.It is highly preferred that the hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol aqueous solution in
The weight fraction of solute is 12%.
Preferably, when carrying out step (1), by the hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol
It is placed in water, is stirred at 80 DEG C, until being uniformly mixed.
Preferably, when carrying out step (2), temperature is 20~40 DEG C.
Preferably, the weight ratio of beta glucan, purple perilla alcohol extract and lucid asparagus water extract is 5:1.5:1.
Another object of the present invention is to provide Essence prepared by the preparation method.
It is also an object of the present invention to provide application of the above-mentioned Essence in terms of skin photoprotection.
Beneficial effects of the present invention:
The present invention light irradiation under, with it is anti-oxidant, remove free radical technical effect, be used for a long time have it is sun-proof,
The function of whitening.
Specific embodiment
The present invention is specifically described below by embodiment, it is necessary to which indicated herein is that following embodiment is only used
It is further detailed in the present invention, should not be understood as limiting the scope of the invention, which is skilled in technique
Some nonessential modifications and adaptations that personnel are made according to foregoing invention content, still fall within protection scope of the present invention.
Embodiment 1
(1) described to prepare the aqueous solution that solute is hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol；
(2) beta glucan, purple perilla alcohol extract and lucid asparagus water extract are added into step (1) obtained aqueous solution, stirring is equal
It is even to get；
Wherein, the weight ratio of beta glucan, purple perilla alcohol extract and lucid asparagus water extract is 5:1.5:1；
The hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol weight ratio be 4:2:2:1:1；The β-
The weight ratio of glucan and hyaluronic acid is 1:7；
The beta glucan is 200,000 dalton by the macromolecular beta glucan and molecular weight that molecular weight is 1,200,000 dalton
Small molecule beta glucan according to weight ratio 1:0.618 form；
The acquisition methods of the purple perilla alcohol extract are as follows:
Purple perilla is cleaned, is dry, dry grain is then comminuted into, the second of 80%v/v is placed in the ratio of solid and liquid weight ratio 1:5
It is carried out refluxing extraction 1.5 hours in alcohol, filtering discards solid formation, and liquid portion is taken to be rotated, and takes gained solid phase powder after revolving
End to get；
The acquisition methods of the lucid asparagus water body object are as follows:
Fresh lucid asparagus is cleaned, its stem is taken, after homogenate, is placed in water back in the ratio of solid and liquid weight ratio 1:2
Stream extract 2 hours, filtering discard solid formation, take liquid portion to be rotated, take revolving after gained solid phase powder to get.
The hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol aqueous solution in the weight fraction of solute be
12%.
When carrying out step (1), the hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol are placed in water
In, it is stirred at 80 DEG C, until being uniformly mixed.
When carrying out step (2), temperature is room temperature, i.e., 20~40 DEG C.
Comparative example 1
Other than lacking purple perilla alcohol extract, remaining is consistent with embodiment 1.
Comparative example 2
Other than lacking lucid asparagus water extract, remaining is consistent with embodiment 1.
Comparative example 3
Other than the weight ratio of beta glucan and hyaluronic acid is adjusted to 1:5, remaining is consistent with embodiment 1.
Experimental example 1
Essence removes DPPH capacity experimental
Material: embodiment 1, comparative example~3 gained Essences, 95% ethyl alcohol, DPPH (analysis is pure), electronic analytical balance,
UV-1600 ultraviolet specrophotometer.
Black purple is presented in DPPH in dehydrated alcohol and ethanol-water system, there is maximum suction at 517nm and 525nm respectively
It receives.Free radical scavenger can make purple gradually retreat, and the content for determining DPPH according to the variation of absorbance and reaction are freely
Scavenging activity of the base scavenger to DPPH.
Precision weighs DPPH3.00mg, and 100ml is dissolved and be settled to 95% ethyl alcohol, and the solubility of DPPH is 20mg/L, is taken
4mlDPPH standard solution, is placed in test tube, be added 1ml it is above-mentioned be diluted to 95% ethyl alcohol 20% Essence, placement
After 30min, absorbance A is measured in 517nm.DPPH clearance rate is measured according to following equation；
The clearance rate of DPPH=[1- (Ai-Aj)/Ac] × 100%
Ai: the absorbance of Essence+4mlDPPH solution
Aj: the absorbance of Essence+4ml95% ethyl alcohol
The absorbance of Ac:1ml95% ethyl alcohol+4mlDPPH solution
DPPH Scavenging activity is indicated with clearance rate, clearance rate is higher, and expression Scavenging activity is stronger, and the results are shown in Table 1.
Table 1
Experimental example 2
20 women are respectively used to using embodiment 1, comparative example~3 gained Essences, under the weather of continuous 5 days fine days
Activity 3 hours in the sun.Application method: first cleaning cutaneous lesion with water, then respectively using embodiment 1, comparative example 1 and right
2 products obtained therefrom of ratio, the 1st day to the 10th day, daily use 1 time, every time uniformly coating 1 time 5 minutes then naturally dry, the 10th
It was used 1 time every other day to 20 days, uniformly coated 1 time 5 minutes then naturally dries every time.
It is observed that being substantially better than the group using comparative example 1,2 or 3 using the sun-proof result of the group of embodiment 1, implementation is used
Crowd's face coloration does not almost find to change with the coloration naked eyes before experiment in the group of example 1, and uses the group of comparative example 1,2 or 3
There is the variable blackening phenomena of naked eyes in coloration before middle crowd's face coloration and experiment.
Experimental example 3
Safety evaluatio: in normal conditions of use, by the application of the subject of experimental example 2, bad thing is determined whether
The generation of part, and exception is checked for according to the degree and vital sign of adverse events, Product Safety is evaluated.
I grades: safety, without any adverse events, vital sign checks without exception.
II grade: relatively safety has slight adverse events, be not required to do any processing can continual cure, vital sign checks nothing
It is abnormal.
III grade: there is safety issue, there are moderate adverse events, it can continual cure or vital sign inspection after processing
Mile abnormality is looked into.
IV grade: because serious adverse events stop test or the obvious exception of vital sign inspection.
Through evaluating, the safety of embodiment 1 and comparative example 3 is I grades, and the safety of comparative example 1 and comparative example 2 is II grade.
Claims (8)
1. a kind of preparation method containing the Essence for photoprotection, which is characterized in that the preparation method includes following step
It is rapid:
(1) described to prepare the aqueous solution that solute is hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol；
(2) beta glucan, purple perilla alcohol extract and lucid asparagus water extract are added into step (1) obtained aqueous solution, stirs evenly, i.e.,
?；
Wherein, the weight ratio of beta glucan, purple perilla alcohol extract and lucid asparagus water extract is 5:1~2:1；
The hyaluronic acid, allantoin, trehalose, hemp seed oil and propylene glycol weight ratio be 4:2:2:1:1；β-the Portugal is poly-
The weight ratio of sugar and hyaluronic acid is 1:7；
The beta glucan is the small of 200,000 dalton by the macromolecular beta glucan and molecular weight that molecular weight is 1,200,000 dalton
Molecule beta glucan is formed according to weight ratio 1:0.618；
The acquisition methods of the purple perilla alcohol extract are as follows:
Purple perilla is cleaned, is dry, dry grain is then comminuted into, is placed in the ethyl alcohol of 80%v/v in the ratio of solid and liquid weight ratio 1:5
It carries out refluxing extraction 1.5 hours, filtering discards solid formation, and liquid portion is taken to be rotated, and takes gained solid phase powder after revolving, i.e.,
?；
The acquisition methods of the lucid asparagus water body object are as follows:
Fresh lucid asparagus is cleaned, its stem is taken, after homogenate, be placed in water in the ratio of solid and liquid weight ratio 1:2 carry out reflux mention
Take 2 hours, filtering discard solid formation, take liquid portion to be rotated, take revolving after gained solid phase powder to get.
2. preparation method according to claim 1, which is characterized in that the hyaluronic acid, allantoin, trehalose, Chinese fiber crops
The weight fraction of solute is 8~16% in seed oil and the aqueous solution of propylene glycol.
3. preparation method according to claim 1, which is characterized in that when carrying out step (1), by the hyaluronic acid,
Allantoin, trehalose, hemp seed oil and propylene glycol are placed in water, and are stirred at 80 DEG C, until being uniformly mixed.
4. preparation method according to claim 1, which is characterized in that when carrying out step (2), temperature is 20~40 DEG C.
5. preparation method according to claim 1, which is characterized in that beta glucan, purple perilla alcohol extract and lucid asparagus water mention
The weight ratio of object is 5:1.5:1.
6. preparation method according to claim 2, which is characterized in that the hyaluronic acid, allantoin, trehalose, Chinese fiber crops
The weight fraction of solute is 12% in seed oil and the aqueous solution of propylene glycol.
7. the Essence being prepared by any one of claim 1~6 preparation method.
8. application of the Essence described in claim 7 in terms of skin photoprotection.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910263920.5A CN109806183B (en) | 2019-04-03 | 2019-04-03 | Preparation method and photoprotection application of beta-glucan-containing essence |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910263920.5A CN109806183B (en) | 2019-04-03 | 2019-04-03 | Preparation method and photoprotection application of beta-glucan-containing essence |
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| CN109806183A true CN109806183A (en) | 2019-05-28 |
| CN109806183B CN109806183B (en) | 2022-03-04 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101884411B1 (en) * | 2017-07-13 | 2018-08-02 | 주식회사 뷰티채널 | Functional cosmetic composition for brighting and moisturizing cream |
| CN108524372A (en) * | 2018-06-26 | 2018-09-14 | 湖南御家化妆品制造有限公司 | A kind of composition and its application in preparing the cosmetics with safeguard function |
-
2019
- 2019-04-03 CN CN201910263920.5A patent/CN109806183B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101884411B1 (en) * | 2017-07-13 | 2018-08-02 | 주식회사 뷰티채널 | Functional cosmetic composition for brighting and moisturizing cream |
| CN108524372A (en) * | 2018-06-26 | 2018-09-14 | 湖南御家化妆品制造有限公司 | A kind of composition and its application in preparing the cosmetics with safeguard function |
Non-Patent Citations (2)
| Title |
|---|
| 张建春: "《汉麻籽综合利用加工技术》", 31 December 2010, 中国轻工业出版社 * |
| 王建新: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
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