CN109789182A - 治疗干眼综合征的方法 - Google Patents
治疗干眼综合征的方法 Download PDFInfo
- Publication number
- CN109789182A CN109789182A CN201780056154.4A CN201780056154A CN109789182A CN 109789182 A CN109789182 A CN 109789182A CN 201780056154 A CN201780056154 A CN 201780056154A CN 109789182 A CN109789182 A CN 109789182A
- Authority
- CN
- China
- Prior art keywords
- subject
- composition
- des
- illness
- eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662363592P | 2016-07-18 | 2016-07-18 | |
| US201662363565P | 2016-07-18 | 2016-07-18 | |
| US62/363,565 | 2016-07-18 | ||
| US62/363,592 | 2016-07-18 | ||
| US201662436727P | 2016-12-20 | 2016-12-20 | |
| US62/436,727 | 2016-12-20 | ||
| PCT/US2017/042382 WO2018017479A1 (en) | 2016-07-18 | 2017-07-17 | Methods of treating dry eye syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109789182A true CN109789182A (zh) | 2019-05-21 |
Family
ID=60992530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780056154.4A Pending CN109789182A (zh) | 2016-07-18 | 2017-07-17 | 治疗干眼综合征的方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10960051B2 (enExample) |
| EP (1) | EP3484497A4 (enExample) |
| JP (1) | JP6889771B2 (enExample) |
| KR (1) | KR102488796B1 (enExample) |
| CN (1) | CN109789182A (enExample) |
| AU (1) | AU2017300268B2 (enExample) |
| CA (1) | CA3031069A1 (enExample) |
| WO (1) | WO2018017479A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7570228B2 (ja) * | 2020-12-25 | 2024-10-21 | ライオン株式会社 | 機械学習実行プログラム、ドライアイ検査プログラム、機械学習実行装置及びドライアイ検査装置 |
| JP2022102757A (ja) * | 2020-12-25 | 2022-07-07 | ライオン株式会社 | 機械学習実行プログラム、ドライアイ検査プログラム、機械学習実行装置及びドライアイ検査装置 |
| JP7570229B2 (ja) * | 2020-12-25 | 2024-10-21 | ライオン株式会社 | 機械学習実行プログラム、ドライアイ検査プログラム、機械学習実行装置及びドライアイ検査装置 |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1638789A (zh) * | 2001-03-15 | 2005-07-13 | 雷金纳克斯生物制药公司 | 用胸腺素β4(Tβ4)、类似物、异构体及其它衍生物治疗眼睛和周围组织失调的方法 |
| CN101102784A (zh) * | 2005-01-13 | 2008-01-09 | 雷金纳克斯生物制药公司 | 对由神经退行性疾病、肌肉退行性疾病、或神经-肌肉退行性疾病所致的组织退化、伤害或损伤进行治疗或预防的方法、或对受到所述疾病的不利影响的组织进行恢复的方法 |
| CN101152568A (zh) * | 2006-09-25 | 2008-04-02 | 宝勒日 | 具有促进血管形成、组织再生及伤口愈合作用的多肽组合制剂 |
| US20080096817A1 (en) * | 1998-07-30 | 2008-04-24 | Regenerx Biopharmaceuticals, Inc. | METHODS OF TREATING DISORDERS OF THE EYE AND SURROUNDING TISSUE WITH THYMOSIN BETA 4 (Tbeta4), ANALOGUES, ISOFORMS AND OTHER DERIVATIVES |
| CN101198344A (zh) * | 2005-06-17 | 2008-06-11 | 雷金纳克斯生物制药公司 | 冻干的或可冻干形式的lkktet和/或lkktnt肽组合物 |
| CN101549148A (zh) * | 2001-08-29 | 2009-10-07 | 雷根内克斯生物制药有限公司 | 多肽在制备用于促进心内膜细胞向间质细胞转化的药物中的应用 |
| CN105106931A (zh) * | 2005-06-17 | 2015-12-02 | 雷金纳克斯生物制药公司 | 冻干的或可冻干形式的lkktet和/或lkktnt肽组合物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05503527A (ja) | 1990-02-22 | 1993-06-10 | マクノート・ピーティーワイ・リミテッド | 人工涙液 |
| KR101258316B1 (ko) | 2007-07-11 | 2013-04-30 | 화이자 인코포레이티드 | 안구 건조증 치료용 약학 조성물 및 방법 |
-
2017
- 2017-07-17 CA CA3031069A patent/CA3031069A1/en active Pending
- 2017-07-17 EP EP17831632.9A patent/EP3484497A4/en not_active Withdrawn
- 2017-07-17 US US16/318,571 patent/US10960051B2/en active Active
- 2017-07-17 AU AU2017300268A patent/AU2017300268B2/en active Active
- 2017-07-17 CN CN201780056154.4A patent/CN109789182A/zh active Pending
- 2017-07-17 KR KR1020197004640A patent/KR102488796B1/ko active Active
- 2017-07-17 JP JP2019503485A patent/JP6889771B2/ja active Active
- 2017-07-17 WO PCT/US2017/042382 patent/WO2018017479A1/en not_active Ceased
-
2021
- 2021-02-25 US US17/185,583 patent/US20210213103A1/en not_active Abandoned
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080096817A1 (en) * | 1998-07-30 | 2008-04-24 | Regenerx Biopharmaceuticals, Inc. | METHODS OF TREATING DISORDERS OF THE EYE AND SURROUNDING TISSUE WITH THYMOSIN BETA 4 (Tbeta4), ANALOGUES, ISOFORMS AND OTHER DERIVATIVES |
| CN1638789A (zh) * | 2001-03-15 | 2005-07-13 | 雷金纳克斯生物制药公司 | 用胸腺素β4(Tβ4)、类似物、异构体及其它衍生物治疗眼睛和周围组织失调的方法 |
| CN101549148A (zh) * | 2001-08-29 | 2009-10-07 | 雷根内克斯生物制药有限公司 | 多肽在制备用于促进心内膜细胞向间质细胞转化的药物中的应用 |
| CN101102784A (zh) * | 2005-01-13 | 2008-01-09 | 雷金纳克斯生物制药公司 | 对由神经退行性疾病、肌肉退行性疾病、或神经-肌肉退行性疾病所致的组织退化、伤害或损伤进行治疗或预防的方法、或对受到所述疾病的不利影响的组织进行恢复的方法 |
| CN101198344A (zh) * | 2005-06-17 | 2008-06-11 | 雷金纳克斯生物制药公司 | 冻干的或可冻干形式的lkktet和/或lkktnt肽组合物 |
| CN105106931A (zh) * | 2005-06-17 | 2015-12-02 | 雷金纳克斯生物制药公司 | 冻干的或可冻干形式的lkktet和/或lkktnt肽组合物 |
| CN101152568A (zh) * | 2006-09-25 | 2008-04-02 | 宝勒日 | 具有促进血管形成、组织再生及伤口愈合作用的多肽组合制剂 |
Non-Patent Citations (4)
| Title |
|---|
| 《老干部之家》编辑部: "《我不是医生 我是健康老人 260名保健明星养生祛病经验集萃》", 31 January 2009 * |
| 司信喜等: ""胸腺肽β_4研究进展"", 《生物技术通讯》 * |
| 李平余: "《中老年人常见眼病》", 31 October 2014, 金盾出版社 * |
| 陈峥: "《老年病诊疗手册》", 31 May 2012, 中国协和医科大学出版社 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019525923A (ja) | 2019-09-12 |
| WO2018017479A1 (en) | 2018-01-25 |
| AU2017300268B2 (en) | 2024-06-13 |
| AU2017300268A1 (en) | 2019-01-31 |
| CA3031069A1 (en) | 2018-01-25 |
| KR20190031280A (ko) | 2019-03-25 |
| US20210213103A1 (en) | 2021-07-15 |
| US10960051B2 (en) | 2021-03-30 |
| EP3484497A1 (en) | 2019-05-22 |
| JP6889771B2 (ja) | 2021-06-18 |
| EP3484497A4 (en) | 2020-01-01 |
| KR102488796B1 (ko) | 2023-01-13 |
| US20190240294A1 (en) | 2019-08-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Yeu et al. | Lotilaner ophthalmic solution, 0.25%, for the treatment of demodex blepharitis: results of a prospective, randomized, vehicle-controlled, double-masked, pivotal trial (Saturn-1) | |
| AU2019358249B2 (en) | Ophthalmic composition for treatment of dry eye disease | |
| Kheirkhah et al. | Corneal manifestations of ocular demodex infestation | |
| Gaddie et al. | Lotilaner ophthalmic solution 0.25% for Demodex blepharitis: randomized, vehicle-controlled, multicenter, phase 3 trial (Saturn-2) | |
| Mastropasqua et al. | Conjunctival goblet cells density and preservative‐free tafluprost therapy for glaucoma: an in vivo confocal microscopy and impression cytology study | |
| JP7012075B2 (ja) | 眼瞼炎の治療に使用するための医薬組成物 | |
| Mastropasqua et al. | In vivo distribution of corneal epithelial dendritic cells in patients with glaucoma | |
| US20090041855A1 (en) | Therapeutic agent for ophthalmic diseases | |
| JP2020502197A (ja) | ドライアイ疾患の治療のための眼科用組成物 | |
| RU2700927C2 (ru) | Офтальмологическая композиция, содержащая циклоспорин и трегалозу | |
| Yamamoto et al. | Topical isopropyl unoprostone for retinitis pigmentosa: microperimetric results of the phase 2 clinical study | |
| Aung et al. | A randomized double-masked crossover study comparing latanoprost 0.005% with unoprostone 0.12% in patients with primary open-angle glaucoma and ocular hypertension | |
| Ruangvaravate et al. | Ocular surface changes after switching from other prostaglandins to tafluprost and preservative-free tafluprost in glaucoma patients | |
| BR112020003276A2 (pt) | métodos de diagnóstico e tratamento da síndrome do olho seco e composições para tratamento de um olho humano | |
| Cheema et al. | Sodium hyaluronate eye drops in the treatment of dry eye disease: an open label, uncontrolled, multi-centre trial | |
| Yeu et al. | Treatment of Demodex blepharitis: a prospective, randomized, controlled, double-masked clinical trial comparing topical lotilaner ophthalmic solution, 0.25% eyedrops to vehicle | |
| Fan et al. | Anthocyanin oligomer (grape skin extract) administration improves dry eye disease: A randomised, double‐blind, placebo‐controlled study | |
| US20210213103A1 (en) | Methods of treating dry eye syndrome | |
| CN113453686A (zh) | 治疗眼表痛的方法 | |
| Kaldırım et al. | Efficacy of hyperbaric oxygen therapy on central corneal thickness, intraocular pressure, and nerve fiber layer in patients with type 2 diabetes: A prospective cohort study | |
| Sakata et al. | Time course of prostaglandin analog-related conjunctival hyperemia and the effect of a nonsteroidal anti-inflammatory ophthalmic solution | |
| Day et al. | Timolol 0.5%/dorzolamide 2% fixed combination vs timolol maleate 0.5% and unoprostone 0.15% given twice daily to patients with primary open-angle glaucoma or ocular hypertension | |
| Kumar et al. | Efficacy and Adverse Effects of Topical Latanoprost with Respect to Preservative in Patients of POAG. | |
| RU2828769C2 (ru) | Офтальмологические композиции для лечения синдрома сухого глаза | |
| RU2850452C2 (ru) | Способы лечения боли на поверхности глаза |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 40012612 Country of ref document: HK |